ライフサイエンスコーパス: single-strand

1 ielding a DNA:RNA hybrid and a displaced DNA single strand.

2 ngth, and T. brucei telomeres terminate in a single-stranded 3' G-rich overhang.

3 nique ribonuclease activity that cleaves the single-stranded 3'-end from tRNAs that contain guanine d

4 We infused a single-stranded adeno-associated viral (AAV) vector cons

5 We found a 60:40 ratio of double- and single-stranded alpha-helix in the highly rigid hydrogel

6 o activities of 1, 2 and 3 GalNAc conjugated single stranded and duplexed ASOs were studied.

7 es to estimate the spontaneous occurrence of single-strand and double-strand breaks (DSB).

8 but also reporter gene expression from both single-stranded and double-stranded (self-complementary)

9 -alkylguanine and O4-alkylthymine adducts in single-stranded and duplex DNAs.

10 echanisms, homologous recombination (HR) and single strand annealing (SSA), and in conferring resista

11 DNA-single strand annealing proteins (SSAPs) are recombinase

12 shifted DSB repair toward highly deleterious single-strand annealing (SSA) and end-joining processes

13 d DNA ends, we addressed the contribution of single-strand annealing factors HR Rad52 and translesion

14 ew amplicons despite the theoretical lack of single-stranded annealing sites.

15 Two and three GalNAc conjugated single stranded ASOs bind the ASGR with the strongest af

16 SSAPs require the activity of their cognate single strand binding (Ssb) proteins.

17 omere binding protein, has an OB domain like single-strand binding protein (SSB1).

18 Uncovering the mechanisms by which single-stranded binding proteins both protect and expose

19 Here we show the critical role of DNA single-strand break (SSB) in the pathogenesis of pressur

20 o 3' excision by exonuclease 1 (Exo1) from a single-strand break 5' to the mispair, excising the misp

21 mes involved in DNA base excision repair and single-strand break repair (SSBR) and is important for g

22 ith APLF joins repair scaffolds that support single-strand break repair and non-homologous end joinin

23 in XRCC1 exhibited not only reduced rates of single-strand break repair but also elevated levels of p

24 A critical step of DNA single-strand break repair is the rapid recruitment of t

25 bles multi-protein complexes involved in DNA single-strand break repair.

26 nteraction module in the regulation of a key single-strand break resection function of APE2, and also

27 etermined the kinetics and thermodynamics of single-stranded break ligation by LIG3alpha and LIG3beta

28 and breaks, and pronounced susceptibility to single-strand breakage.

29 DP-ribosyltransferases promote repair of DNA single strand breaks and disruption of this pathway by P

30 r near-normal XRCC1 recruitment at oxidative single-strand breaks (SSBs) as indicated by the requirem

31 ng a molecular mechanism by which endogenous single-strand breaks trigger neuropathology.

32 th DNA strands in the ICL without generating single-strand breaks.

33 Under optimised sensing conditions, the single stranded CCCVd RNA oligonucleotide target could b

34 obases at 37 degrees C from both double- and single-stranded circular template DNA using specific pri

35 "Blunt-ended" tiles do not have single-stranded complementary ends, and thus instead of

36 e detected for the telomere repeat TTAGGG in single-stranded configuration, showing that secondary st

37 h-resolution capillary electrophoresis-based single-strand conformation polymorphism (CE-SSCP).

38 To address this, we developed a new single-strand consensus sequencing assay for the determi

39 e-strand breaks, while ATR deals mainly with single-strand damage.

40 educed graphene oxide aerogel labeled with a single strand DNA (ss-HSDNA/rGOae) modified on a rotatin

41 de experimental evidence that ComFA binds to single stranded DNA (ssDNA) and has ssDNA-dependent ATPa

42 ipment and facilitates the immobilization of single stranded DNA (ssDNA) probe sequences on a wide va

43 ed through pH-assisted thiol-gold bonding of single stranded DNA and salt aging, with preconjugated b

44 telomeric G-quadruplex DNA to complementary single stranded DNA and to telomere binding protein POT1

45 An amino-modified single stranded DNA oligonucleotide probe synthesised ba

46 ped AuNPs and the d-AuNPs were stabilized by single stranded DNA probe (ssDNAp).

47 stranded MLPA products and subsequently to a single stranded DNA reporter probe bearing a HRP molecul

48 ch is able to detect hybridization of probe (single stranded DNA-ssDNA) and hybrid (double stranded D

49 Specifically, PtNPs are modified with a single-strand DNA (ssDNA) shell that is complementary to

50 e the identification of RADX as an RPA-like, single-strand DNA binding protein.

51 t are unable to form t-loops or complex with single-strand DNA binding proteins, raising the question

52 y-mediated end-joining requires annealing of single-strand DNA ends, we addressed the contribution of

53 Single-strand DNA molecules are introduced into DNA@ZIF-

54 choice is determined by the generation of 3 single-strand DNA overhangs at the break that are initia

55 , AddAB or AdnAB) generates the requisite 3' single-strand DNA substrate for RecA-mediated strand inv

56 hannel of the N-tier and the unwound leading single-strand DNA traverses the channel through the N-ti

57 ent optical properties and biocompatibility, single-strand DNA-functionalized quantum dots have been

58 s, as well as numerous circular Rep-encoding single-stranded DNA (CRESS DNA) viral genomes, were iden

59 RPA-coated single-stranded DNA (RPA-ssDNA), a nucleoprotein structu

60 ate-free synthesis of high-molecular-weight, single-stranded DNA (ssDNA) and demonstrate that it proc

61 nnealase, a protein that binds complementary single-stranded DNA (ssDNA) and facilitates its annealin

62 A orchestrates these processes by binding to single-stranded DNA (ssDNA) and interacting with several

63 Human RAD52 has been shown to mediate single-stranded DNA (ssDNA) and is synthetic lethal with

64 Single-stranded DNA (ssDNA) and RNA regions that include

65 The bacterial single-stranded DNA (ssDNA) binding protein SSB is a str

66 The 2 single-stranded DNA (ssDNA) binding proteins SSB1 and SS

67 The single-stranded DNA (ssDNA) cytidine deaminase APOBEC3F

68 The APOBEC3B (A3B) single-stranded DNA (ssDNA) cytosine deaminase has impor

69 through the cell cytoplasm, and deliver the single-stranded DNA (ssDNA) genome to the nucleus, where

70 n genome maintenance, binding and organizing single-stranded DNA (ssDNA) intermediates.

71 Single-stranded DNA (ssDNA) is notable for its interacti

72 epsilon has greater contact with the nascent single-stranded DNA (ssDNA) of the leading strand on act

73 nerated DSB ends are processed to yield long single-stranded DNA (ssDNA) overhangs, which are quickly

74 te of cytosine deamination is much higher in single-stranded DNA (ssDNA) than in double-stranded DNA,

75 egy relies on the preferential adsorption of single-stranded DNA (ssDNA) to GO over aptamer-target co

76 ons or by template-directed synthesis with a single-stranded DNA (ssDNA) topological structure.

77 tion and genomic substitution rates, RNA and single-stranded DNA (ssDNA) viruses may be important con

78 gle-stranded DNA binding protein (SSB) wraps single-stranded DNA (ssDNA) with high affinity to protec

79 (AFM) to show that Ver preferentially binds single-stranded DNA (ssDNA) with no sequence specificity

80 ate containing RNA:DNA hybrids and displaced single-stranded DNA (ssDNA), has emerged as a major sour

81 on of the DNA damage signal, accumulation of single-stranded DNA (ssDNA), sensitivity to replication

82 sitive coactivator of transcription (PC4), a single-stranded DNA (ssDNA)-binding protein, as a novel

83 Strikingly, the addition of the single-stranded DNA (ssDNA)-binding replication protein

84 ly 2 helicase Hel308 during translocation on single-stranded DNA (ssDNA).

85 rand synthesis leads to accumulation of long single-stranded DNA (ssDNA).

86 sive processing, producing long stretches of single-stranded DNA (ssDNA).

87 PF and ERCC-XPF and show that the binding to single-stranded DNA (ssDNA)/dsDNA junctions is dependent

88 rial strategies (1) , especially small lytic single-stranded DNA (the microviruses) and RNA phages (t

89 The microbial target, single-stranded DNA amplified with asymmetric PCR, was q

90 lyzed, radical reaction process that cleaves single-stranded DNA and requires only redox-inactive met

91 nzymes, dimerization enables processivity on single-stranded DNA and results in higher levels of muta

92 exed, expanded proteomic technique that uses single-stranded DNA aptamers to assay 4783 human protein

93 RNA or single-stranded DNA aptamers with 2'-F pyrimidines have

94 hods for autonomously synthesizing arbitrary single-stranded DNA are limited.

95 iring lesions using double-stranded, but not single-stranded DNA as a template.

96 Here the authors show that APOBEC3G binds single-stranded DNA as an active deaminase monomer, subs

97 We have investigated the dynamics of single-stranded DNA as it translocates through charge-mu

98 nthetic sequence that mimics freshly unwound single-stranded DNA at replication fork showed that RPA

99 when recombinantly expressed had the general single-stranded DNA binding activity of RPA complexes, u

100 Here we measure the single-stranded DNA binding and oligomerization kinetics

101 ralogous to the large subunit of the general single-stranded DNA binding heterotrimer replication pro

102 The bacterial single-stranded DNA binding protein (SSB) acts as an org

103 The single-stranded DNA binding protein (SSB) of Escherichia

104 During DNA replication, the single-stranded DNA binding protein (SSB) wraps single-s

105 The nascent DNA colocalized with the VACV single-stranded DNA binding protein I3 in multiple punct

106 factor IIH prevented the accumulation of the single-stranded DNA binding protein replication protein

107 hairpin RNA (shRNA) screening, we identified single-stranded DNA binding protein replication protein

108 loader, the PCNA sliding clamp, and the RPA single-stranded DNA binding protein.

109 These results reveal the role of single-stranded DNA binding proteins in controlling Exo1

110 ains to distinguish the PriA interaction and single-stranded DNA binding.

111 Human APOBEC3H and homologous single-stranded DNA cytosine deaminases are unique to ma

112 APOBEC3s (A3s) are single-stranded DNA cytosine deaminases that provide inn

113 -CRISPR), a targeting strategy in which long single-stranded DNA donors are injected with pre-assembl

114 A double-strand breaks (DSBs) to generate 3'-single-stranded DNA facilitates DSB repair via error-fre

115 The separation and partitioning of large single-stranded DNA fragments of the homologous chromoso

116 We demonstrated that Brca2 protein prevents single-stranded DNA gap accumulation at replication fork

117 tions arise through the aberrant repair of a single-stranded DNA gap, in a process that is dependent

118 RarA ATPase activity is stimulated by single-stranded DNA gaps and double-stranded DNA ends.

119 determine how they contribute to duplex and single-stranded DNA handling, and test the cellular cons

120 ded binding proteins both protect and expose single-stranded DNA has important implications for our u

121 uble-stranded DNA in its ATP-bound state and single-stranded DNA in its apo state.

122 unequivocally establishes the existence of a single-stranded DNA incorporation pathway in human cells

123 zes synthesis-dependent strand annealing and single-stranded DNA incorporation pathways.

124 ude that ROS contribute to TLD by converting single-stranded DNA lesions into double-stranded DNA bre

125 NA hybridized to the complementary DNA and a single-stranded DNA loop, are formed in switch regions o

126 pose that these contigs correspond to linear single-stranded DNA molecules that fold onto themselves

127 olecule arrays by electrostatically adhering single-stranded DNA of gene-like length onto positively

128 ce receptor of interest is conjugated with a single-stranded DNA oligonucleotide, which hybridizes to

129 tutions via HDR following co-delivery with a single-stranded DNA oligonucleotide.

130 Single-stranded DNA oligonucleotides have unique, and in

131 ins for Proteomics) is an approach that uses single-stranded DNA oligonucleotides to capture specific

132 and diffusion constants of several different single-stranded DNA oligonucleotides trapped in an MspA

133 hydrolysis, although they both cleave simple single-stranded DNA oligonucleotides.

134 fficient covalent immobilization of purified single-stranded DNA probe oligomers on cleaned gold micr

135 ine starvation leads to accumulation of both single-stranded DNA regions and intracellular ROS, and i

136 ivery of CRISPR/Cpf1 ribonucleoproteins with single-stranded DNA repair templates results in precise

137 nd resection, which generates long tracts of single-stranded DNA required for checkpoint activation a

138 High-throughput single-stranded DNA sequencing (ssDNA-seq) of cell-free

139 gents, to prime second strand synthesis of a single-stranded DNA template and generate millions of pa

140 d both must remodel onto opposite strands of single-stranded DNA to do so.

141 In the case of the ubiquitous human circular single-stranded DNA virus family Anelloviridae, there is

142 Circular single-stranded DNA viruses infect archaea, bacteria, an

143 The relatively recent emergence of single-stranded DNA viruses, such as chicken anemia viru

144 o reach up to 22 hours, whereas unconjugated single-stranded DNA was degraded within minutes.

145 ore, the measurements of thermally denatured single-stranded DNA were carried out and the value of (G

146 Elevated levels of single-stranded DNA were necessary but insufficient for

147 eir destinations allows for a simple robot a single-stranded DNA with one leg and two foot domains fo

148 reaction (PER) cascades, which grow nascent single-stranded DNA with user-specified sequences follow

149 tional R-loops (RNA/DNA duplex and displaced single-stranded DNA) and DNA double-strand breaks (DSBs)

150 on associated with increased accumulation of single-stranded DNA, a substrate of APOBEC3A, triggering

151 bustly with specific sequences of unmodified single-stranded DNA, and we have identified five tags th

152 an essential replisome component that binds single-stranded DNA, has a role in replication-coupled n

153 sequence, the proteinosome payload (dextran, single-stranded DNA, platinum nanoparticles) is traffick

154 ese mutants compared with wild type DnaC for single-stranded DNA, suggesting that the substitutions a

155 tides, called staple strands, to fold a long single-stranded DNA, which is called a scaffold strand,

156 for deaminating cytosine bases to uracil in single-stranded DNA, with characteristic sequence prefer

157 ethods, this amplification requires only the single-stranded DNA-binding protein gp32 from bacterioph

158 nal proteins, including the telomeric repeat single-stranded DNA-binding protein Teb1 and its heterot

159 Single-stranded DNA-binding proteins (SSBs) play a key r

160 d of telomeric sequence-specific double- and single-stranded DNA-binding proteins, Taz1 and Pot1, res

161 Here, we present a study of surfactant and single-stranded DNA-wrapped SWNTs suspended in aqueous s

162 s comprise an RNA/DNA hybrid and a displaced single-stranded DNA.

163 ation of transcription from both double- and single-stranded DNA.

164 First, we modified a glass surface with single-stranded DNA.

165 ish this task, RAD51 must be loaded onto the single-stranded DNA.

166 hrough deaminating cytosine (C) to uracil on single-stranded DNA/RNA.

167 nctionalized and codified with two different single stranded-DNA (ssDNA) chains.

168 We recently demonstrated that long single-stranded DNAs (ssDNAs) serve as very efficient do

169 on ssDNA facilitates 5' flap cleavage near a single-strand-double strand junction while attenuating 3

170 We found that XPA binds different single-stranded/double-stranded junction DNA substrates

171 s comprised of double-stranded DNA with a 3' single-stranded extension.

172 delocalized phonon-like modes in DNA provide single-stranded "flexible hinges" to assist in loop form

173 Agrobacterium strains transfer a single-strand form of T-DNA (T-strands) and Virulence (V

174 s is formation of a heteroduplex, in which a single-strand from the broken DNA molecule pairs with a

175 rand DNA by facilitating Exo1 loading onto a single strand gap at the stalled replication fork.

176 processing nucleases, in order to close the single-stranded gap and terminate further resection.

177 Instead, we detected R-gaps, single-strand gaps containing rNs, in the chromosomal DN

178 We also identify single-stranded gaps as plausible deletion precursors, p

179 ble-stranded DNA breaks (SSBs and DSBs), and single-stranded gaps can block progression of the DNA re

180 ite having vastly different propensities for single-stranded helical stacking.

181 adruplexes formed by folding of GGG(TTAGGG)3 single strands in buffered solutions containing Na(+) ca

182 tes that the folding landscapes of short DNA single strands is much more complex than previously assu

183 sulting in the exposure of long stretches of single-stranded leading-strand template.

184 This method combines an ultra-sensitive single-stranded library construction with barcoding erro

185 cing System of Digitalized Barcode Encrypted Single-stranded Library from Extremely Low (quality and

186 tructures (duplex, hairpin, G-quadruplex and single-stranded), ligand types (ion, small organic molec

187 stabilized by specific insertion of a short single-stranded linker.

188 Single-stranded miRNAs inhibitors were used to block sel

189 manufactured electrode array and exposed to single-stranded MLPA products and subsequently to a sing

190 tem is composed of two nanoconjugates: (1) a single-stranded morpholino oligonucleotide (MORF1) attac

191 Alternatively, hUPF1 binds to single-stranded NAs (ssNA) with apparent affinity increa

192 Mononegaviruses have non-segmented, single-stranded negative-sense RNA genomes that are enca

193 ion of U:G mismatches is translated into the single-strand nick required for error-prone synthesis is

194 signal (a hemi-methylated d(GATC) site or a single-stranded nick) and the replication error after th

195 avirales is composed of viruses that possess single-stranded, non-segmented negative-sense (NNS) RNA

196 spindle tuber viroid (PSTVd) is a circular, single-stranded, noncoding RNA plant pathogen that is a

197 Single-stranded nucleic acids (ssNAs) are ubiquitous in

198 semble of flexible polyelectrolytes, such as single-stranded nucleic acids (ssNAs), is complicated by

199 tic domain (CD2) alone is capable of binding single-stranded nucleic acids and is important for deami

200 to enable them to bind a variable number of single-stranded nucleotides depending on the salt and pr

201 eat to transfer G-quadruplex conformation to single strand of DNA sequence and release thrombin.

202 of a commercial Cas9 protein:crRNA:tracrRNA:single-strand oligodeoxynucleotide (ssODN) complex into

203 a CRISPR plasmid expressing Cas9/gRNA and a single-stranded oligodeoxynucleotide HDR donor template

204 ization of FOXO protein via CRISPR-assisted, single-stranded oligodeoxynucleotide-mediated homology-d

205 ADAPT employs an enriched library of single-stranded oligodeoxynucleotides (ssODNs) to profil

206 onversion with either double-stranded DNA or single-stranded oligonucleotide donors by up to 5.6-fold

207 DNA logic gate circuits typically provide a single-stranded oligonucleotide output, limiting the abi

208 and internalization of highly polar anionic single stranded oligonucleotides into cells and tissues.

209 overhangs in opposite orientations to which (single-strand) oligos rather than (double-stranded) adap

210 d this pattern held true whether the DNA was single-stranded or duplex.

211 strate recognition by capturing two adjacent single-stranded overhangs simultaneously.

212 Hepatitis C virus (HCV) is a single-stranded positive-sense RNA hepatotropic virus.

213 Hepatitis E virus (HEV), a single-stranded positive-sense RNA virus, generally caus

214 Fluorescently labeled single stranded probe strands and graphene oxide nanoass

215 sively copied, and regenerated by release of single-stranded product DNA.

216 ransduced by the double-stranded but not the single-stranded recombinant AAV2 vectors progressed thro

217 unds, and that motifs are found in a loop or single stranded region of the potential RNA secondary st

218 e many different aspects of RNA ranging from single stranded regions to discrete secondary or tertiar

219 Single-stranded regions in such RNAs contribute to bindi

220 expressed COL1A gene, and co-injected with a single-stranded repair template into porcine zygotes.

221 xygen species, NOX2 oxidase, is activated by single stranded RNA and DNA viruses in endocytic compart

222 or the replication of various positive-sense single stranded RNA viruses, which hijack this cellular

223 ate that M. tuberculosis RpsA interacts with single stranded RNA, but not with POA.

224 ssential host factor for many positive-sense single-stranded RNA (+RNA) viruses including human patho

225 important roles in inhibiting positive-sense single-stranded RNA (+ssRNA) viral infection, especially

226 Higher ratios of HCV double-stranded to single-stranded RNA (ssRNA) correlated positively with I

227 show that topological structures containing single-stranded RNA (ssRNA) free of strong base pairing

228 ata from a competition assay between SLA and single-stranded RNA (ssRNA) indicate that SLA competes w

229 ndicates that small phages, particularly the single-stranded RNA (ssRNA) leviviruses, have a previous

230 The recent discovery of the positive-sense single-stranded RNA (ssRNA) Orsay virus (OV) as a natura

231 ly for adenoviruses, which resembles that of single-stranded RNA (ssRNA) viruses but differs from the

232 h pump their genome into a preformed capsid, single-stranded RNA (ssRNA) viruses, such as bacteriopha

233 rified human PRC2 recognizes G > C,U >> A in single-stranded RNA and has a high affinity for folded g

234 In single-stranded RNA bacteriophages (ssRNA phages) a sing

235 tion motif, domains are the largest class of single-stranded RNA binding domains in the human proteom

236 s a protein conformational change induced by single-stranded RNA binding.

237 the HIV-1 genome, which is in the form of a single-stranded RNA enclosed inside a capsid shell, must

238 The virus possesses a negative-sense single-stranded RNA genome of approximately 13.3 kb enca

239 nonenveloped icosahedral virions containing single-stranded RNA genomes.

240 the transcription of the relatively flexible single-stranded RNA into a more rigid filamentous struct

241 70) is a demethylase that removes m(6)A from single-stranded RNA molecules in vitro.

242 (CCMV) is capable of packaging both purified single-stranded RNA molecules of normal composition (com

243 se H activity that act in concert to convert single-stranded RNA of the viral genome to double-strand

244 Aptamers are single-stranded RNA or DNA molecules that have recently

245 A virus (IAV) genomes are composed of eight single-stranded RNA segments that are coated by viral nu

246 lex RNA regardless of the orientation of the single-stranded RNA tail, it preferred a 5' to 3' polari

247 Previously, a stochastic model of single-stranded RNA virus assembly was created to model

248 arainfluenza virus (PIV) is a negative-sense single-stranded RNA virus in the Paramyxoviridae family.

249 With Coxsackievirus B3 (CVB3) being a single-stranded RNA virus, and the recent evidence that

250 n is a common strategy among positive-sense, single-stranded RNA viruses for bypassing the host cell

251 Flaviviruses are positive-sense, single-stranded RNA viruses responsible for millions of

252 stroviruses are nonenveloped, positive-sense single-stranded RNA viruses that cause gastrointestinal

253 ity of identified viruses are positive-sense single-stranded RNA viruses.

254 DNA data is transcribed into single-stranded RNA, which folds into specific molecular

255 ng others responsible for the recognition of single-stranded RNA.

256 esis is potently inhibited by the binding of single-stranded RNA.

257 kinase is not activated by and does not bind single-stranded RNA.

258 the Grc3 kinase activity exclusively toward single-stranded RNA.

259 Single-stranded RNAs also activate PKR constructs lackin

260 Here, we demonstrate that single-stranded RNAs bind to PKR with micromolar dissoci

261 Circular RNAs (circRNAs) are single-stranded RNAs that are joined head to tail with l

262 the 5'-phosphate and 3'-hydroxyl termini of single-stranded RNAs.

263 of a uridine two nucleotides downstream in a single-stranded segment, which we rationalize structural

264 ically binding the terminal loop near the 3' single-stranded segment.

265 active as nucleoprotein filaments formed on single-stranded segments of DNA.

266 tiated by uracil-DNA glycosylase (UNG) or by single-strand selective monofunctional uracil DNA glycos

267 we report a method, which is dubbed SISSOR (single-stranded sequencing using microfluidic reactors),

268 oplex destabilization to release double- and single-strand siRNA and/or smaller siRNA-lipid complexes

269 E. coli single strand (ss) DNA binding protein (SSB) is an essen

270 sequence the three-dimensional structures of single stranded (ss) DNA required for aptamer applicatio

271 RICE proteins specifically degraded single-strand (ss) RNAs in vitro; but neither miRNAs nor

272 FEN1 precisely cleaves single-stranded (ss) 5'-flaps one nucleotide into duplex

273 lular RNAs inhibits A3G binding to substrate single-stranded (ss) DNA and CDA activity.

274 at an icosahedral fivefold vertex and induce single-stranded (ss) DNA genome ejection.

275 DNA replication forks generates stretches of single-stranded (ss) DNA on both strands that are expose

276 Such studies often embed a single-stranded (ss) DNA region within a longer double-s

277 of these activities is its ATP-driven 3'-5' single-stranded (ss) DNA translocation activity.

278 eless preserve closed circular DNA in either single-stranded (SS) or double-stranded (DS) form.

279 for the first time, the interaction of long single-stranded (ss) RNAs with cognate homologous double

280 We have established single-stranded (ss)DNA curtain assays for measuring ind

281 ch we find to be similar to that of the pure single-stranded state.

282 perimentally construct diverse multikilobase single-stranded structures, including a 10,000-nucleoti

283 mportant for the processing of DNA ends into single-stranded substrates for homologous recombination.

284 lization of CpG oligodeoxynucleotide 1826, a single-stranded synthetic DNA adjuvant, eliciting an enh

285 r, G4-T-oligo has similar cellular uptake as single-stranded T-oligo, as shown by FACS analysis.

286 ased antiproliferative effects compared with single-stranded T-oligo.

287 G4-T-oligo was found to be more stable than single-stranded T-oligo.

288 yeast, these breaks are resected to form 3' single-strand tails that participate in a homology searc

289 With the exception of the single-stranded telomeric DNA, all genomic G-rich sequen

290 c mutations in hPOT1 OB-fold fail to bind to single-stranded telomeric DNA, eliciting a DNA damage re

291 lted out into a transcription bubble and the single-stranded template DNA is delivered to the RNAP ac

292 leolytic resection of DNA ends to generate a single-stranded template for the recruitment of another

293 NAP-promoter open complex (RPo) containing a single-stranded 'transcription bubble,' and selects a tr

294 sylase that only acts on double-stranded and single-stranded uracil-containing DNA.

295 signature sequence, a GAUC repeat framed by single-stranded uridines.

296 Here, we created site-specifically modified single-stranded vectors for replication in primate (COS7

297 The viruses, all positive sense single-stranded, were classified into diverse orders/fam

298 e the biomolecular interplay that G-rich DNA single-strands with one-end confined on graphene surface

299 g and protein capture of the displaced 3'-OH single strand, without a need for extensive end-resectio

300 Experimentally, a single-stranded zig-zag chain of phosphorus atoms was ob