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1 First, we modified a glass surface with single-stranded DNA.
2 ish this task, RAD51 must be loaded onto the single-stranded DNA.
3 yed as the redox indicator binding better to single-stranded DNA.
4 as the experimental approaches used to pull single-stranded DNA.
5 een the unwinding substrate and a homologous single-stranded DNA.
6 of the MCM work in concert to translocate on single-stranded DNA.
7 mplex that is required for loading DnaB onto single-stranded DNA.
8 ' oriented laying out of hRPA subunits along single-stranded DNA.
9 ated NPH I acts as a 5' to 3' translocase on single-stranded DNA.
10 ction, via its BRCT2 domain, with RPA-coated single-stranded DNA.
11 asize the lesser-known elastic properties of single-stranded DNA.
12 igh levels of hyperphosphorylated RPA-loaded single-stranded DNA.
13 1 protease is accelerated in the presence of single-stranded DNA.
14 d magnetic beads and macromolecular coils of single-stranded DNA.
15 ATPase activity of MtRecD was stimulated by single-stranded DNA.
16 rameters resembling enzymes translocating on single-stranded DNA.
17 bound to a parallel quadruplex compared with single-stranded DNA.
18 s comprise an RNA/DNA hybrid and a displaced single-stranded DNA.
19 ation of transcription from both double- and single-stranded DNA.
20 on associated with increased accumulation of single-stranded DNA, a substrate of APOBEC3A, triggering
22 CNA-related trimer is loaded onto RPA-coated single stranded DNA and interacts with ATR kinase to med
23 ed through pH-assisted thiol-gold bonding of single stranded DNA and salt aging, with preconjugated b
24 telomeric G-quadruplex DNA to complementary single stranded DNA and to telomere binding protein POT1
25 lyzed, radical reaction process that cleaves single-stranded DNA and requires only redox-inactive met
26 nzymes, dimerization enables processivity on single-stranded DNA and results in higher levels of muta
27 e selectivity of such a system in binding to single-stranded DNA and RNA is quadratically better than
28 e and reveals new interactions between short single-stranded DNA and the vestibule of a biological po
29 orts as to whether the enzyme also possesses single-stranded DNA and/or RNA 3'-5' exonuclease activit
30 tional R-loops (RNA/DNA duplex and displaced single-stranded DNA) and DNA double-strand breaks (DSBs)
31 H, which fills the Pol II active center with single-stranded DNA, and subsequent scanning downstream,
32 bustly with specific sequences of unmodified single-stranded DNA, and we have identified five tags th
33 binding of the human thrombin and its 15-mer single stranded DNA aptamer, under the application of ex
34 , and high-affinity PET radioligand based on single-stranded DNA aptamer to address this challenge.
36 exed, expanded proteomic technique that uses single-stranded DNA aptamers to assay 4783 human protein
38 eve accurate annealing when large regions of single-strand DNA are unpaired has remained unclear desp
41 Here the authors show that APOBEC3G binds single-stranded DNA as an active deaminase monomer, subs
45 nthetic sequence that mimics freshly unwound single-stranded DNA at replication fork showed that RPA
48 by the reliance of separation in DQAMmiR on single-strand DNA binding protein (SSB) whose native str
50 t are unable to form t-loops or complex with single-strand DNA binding proteins, raising the question
51 when recombinantly expressed had the general single-stranded DNA binding activity of RPA complexes, u
54 ralogous to the large subunit of the general single-stranded DNA binding heterotrimer replication pro
60 The nascent DNA colocalized with the VACV single-stranded DNA binding protein I3 in multiple punct
61 terize the role of filament formation by the single-stranded DNA binding protein ICP8 in the formatio
63 lymerase gamma holoenzyme, the mitochondrial single-stranded DNA binding protein mtSSB, the replicati
64 factor IIH prevented the accumulation of the single-stranded DNA binding protein replication protein
65 hairpin RNA (shRNA) screening, we identified single-stranded DNA binding protein replication protein
72 ethods, this amplification requires only the single-stranded DNA-binding protein gp32 from bacterioph
73 A (RPA) is a highly conserved heterotrimeric single-stranded DNA-binding protein involved in DNA repl
75 nal proteins, including the telomeric repeat single-stranded DNA-binding protein Teb1 and its heterot
79 d of telomeric sequence-specific double- and single-stranded DNA-binding proteins, Taz1 and Pot1, res
81 fferentiation was observed, due to increased single-strand DNA breaks that likely occur due to hetero
82 Moreover, a predominant binding of PARP1 to single-strand DNA breaks, occluding its Erk binding site
83 ive solvent environment that can concentrate single-stranded DNA but largely exclude double-stranded
87 pecificity of anti-lipid A antibodies toward single-stranded DNA combined with observed homology of S
89 ion and emission shift of up to 120 nm for a single-stranded DNA construct, and (3) a sequence robust
90 s, as well as numerous circular Rep-encoding single-stranded DNA (CRESS DNA) viral genomes, were iden
93 ng proteins, initiating the cell response to single-strand DNA damage, was also required for long-ter
94 -CRISPR), a targeting strategy in which long single-stranded DNA donors are injected with pre-assembl
95 mbination of alternating double-stranded and single-stranded DNA (dsDNA and ssDNA) regions of varying
96 y-mediated end-joining requires annealing of single-strand DNA ends, we addressed the contribution of
98 f TER in the TERT-TER-p65 catalytic core and single-stranded DNA exit; extensive subunit interactions
99 A double-strand breaks (DSBs) to generate 3'-single-stranded DNA facilitates DSB repair via error-fre
100 applied directional deep sequencing of short single-stranded DNA fragments enriched for RNA-primed na
101 The separation and partitioning of large single-stranded DNA fragments of the homologous chromoso
102 on of the structure of S1-15 in complex with single-stranded DNA fragments, which may provide clues a
103 ent optical properties and biocompatibility, single-strand DNA-functionalized quantum dots have been
105 We demonstrated that Brca2 protein prevents single-stranded DNA gap accumulation at replication fork
106 tions arise through the aberrant repair of a single-stranded DNA gap, in a process that is dependent
109 phosphate, and also for cytosine residues in single-stranded DNA generated from a phagemid, in which
112 determine how they contribute to duplex and single-stranded DNA handling, and test the cellular cons
113 ded binding proteins both protect and expose single-stranded DNA has important implications for our u
114 an essential replisome component that binds single-stranded DNA, has a role in replication-coupled n
115 yme that specifically modifies thymidines on single-stranded DNA in a sequence-specific manner by a n
116 nduced DSBs are efficiently resected into 3' single-stranded DNA in cells and the major nuclease for
120 unequivocally establishes the existence of a single-stranded DNA incorporation pathway in human cells
123 rmation and maintenance of the double-strand/single-strand DNA junction at the upstream edge of the -
124 e adapters; subsequent PCR steps amplify the single-stranded DNA junction library in preparation for
125 gy presented by the upstream double-stranded/single-stranded DNA junction of the transcription bubble
127 ude that ROS contribute to TLD by converting single-stranded DNA lesions into double-stranded DNA bre
128 The aptamers were selected in vitro from a single-stranded DNA library of 1.8 x 10(15) oligonucleot
129 NA hybridized to the complementary DNA and a single-stranded DNA loop, are formed in switch regions o
130 cancer (PCa) that specifically binds to the single-stranded DNA molecule from a 277-nt fragment that
133 pose that these contigs correspond to linear single-stranded DNA molecules that fold onto themselves
134 ate recombination (SPDIR), facilitates short single-stranded DNA molecules to invade and replace geno
135 eads by measuring changes in ionic flow when single-stranded DNA molecules translocate through the po
136 mine the thermal motion of a voltage-clamped single-stranded DNA-NeutrAvidin complex in a Mycobacteri
137 olecule arrays by electrostatically adhering single-stranded DNA of gene-like length onto positively
139 nal DNA origami, the DNR scaffold is a long, single-stranded DNA of tandem repeats, originating from
140 BAC simultaneously by co-transformation of a single-stranded DNA oligo and a double-stranded selectio
142 ce receptor of interest is conjugated with a single-stranded DNA oligonucleotide, which hybridizes to
147 ins for Proteomics) is an approach that uses single-stranded DNA oligonucleotides to capture specific
148 and diffusion constants of several different single-stranded DNA oligonucleotides trapped in an MspA
153 ination (HR) requires the generation of a 3' single-strand DNA overhang by exonuclease activities in
154 choice is determined by the generation of 3 single-strand DNA overhangs at the break that are initia
155 sequence, the proteinosome payload (dextran, single-stranded DNA, platinum nanoparticles) is traffick
156 and Rad52 to promote nucleation of Rad51 on single-stranded DNA pre-occupied by replication protein
158 which is able to detect the hybridization of single stranded DNA probe with its complementary target
159 fficient covalent immobilization of purified single-stranded DNA probe oligomers on cleaned gold micr
160 orters we conjugated it to one terminus of a single-stranded DNA "probe" that was attached by its oth
162 ate in methylated regions involving frequent single-stranded DNA processing as part of DSB repair.
163 ine starvation leads to accumulation of both single-stranded DNA regions and intracellular ROS, and i
164 by facilitating the generation of RPA-bound single-stranded DNA regions upon replication stress in a
165 ivery of CRISPR/Cpf1 ribonucleoproteins with single-stranded DNA repair templates results in precise
166 stranded MLPA products and subsequently to a single stranded DNA reporter probe bearing a HRP molecul
167 nd resection, which generates long tracts of single-stranded DNA required for checkpoint activation a
170 lection of high-affinity reagents based upon single-stranded DNA scaffolding of peptide fragments.
173 lity through the introduction of an unpaired single-stranded DNA spacer in the middle of each duplex.
175 y of S1-15 and A6 and the reports of several single-stranded DNA-specific mAbs prompted the determina
177 educed graphene oxide aerogel labeled with a single strand DNA (ss-HSDNA/rGOae) modified on a rotatin
178 ions in the lattices using responsiveness of single-stranded DNA (ss-DNA), far less work has been don
179 de experimental evidence that ComFA binds to single stranded DNA (ssDNA) and has ssDNA-dependent ATPa
181 fication, hybridisation between short 25-mer single stranded DNA (ssDNA) fragments and a complementar
182 ipment and facilitates the immobilization of single stranded DNA (ssDNA) probe sequences on a wide va
186 Specifically, PtNPs are modified with a single-strand DNA (ssDNA) shell that is complementary to
187 quantities of DNA sequence to align and pair single-strand DNA (ssDNA) with a homologous double-stran
188 ultiple target DNAs causes the corresponding single-stranded DNA (ssDNA) amplicons to be generated an
189 ich forms helical nucleoprotein filaments on single-stranded DNA (ssDNA) and catalyzes strand invasio
190 ate-free synthesis of high-molecular-weight, single-stranded DNA (ssDNA) and demonstrate that it proc
191 anine (G), Cytosine (C), and Thymine (T)) on single-stranded DNA (ssDNA) and double-stranded DNA (dsD
192 nnealase, a protein that binds complementary single-stranded DNA (ssDNA) and facilitates its annealin
193 A orchestrates these processes by binding to single-stranded DNA (ssDNA) and interacting with several
196 or surface of hexameric helicases to protect single-stranded DNA (ssDNA) and stabilize the complex in
197 s a nucleoprotein filament that assembles on single-stranded DNA (ssDNA) at the sites of DNA damage.
199 his process is driven by the essential viral single-stranded DNA (ssDNA) binding protein ICP8, which
201 cation protein A (RPA), the major eukaryotic single-stranded DNA (ssDNA) binding protein, is essentia
203 divergent bacteria can recognize and cleave single-stranded DNA (ssDNA) by an RNA-guided, PAM-indepe
209 through the cell cytoplasm, and deliver the single-stranded DNA (ssDNA) genome to the nucleus, where
210 to track the population of unlabeled target single-stranded DNA (ssDNA) hybridized with probe DNA im
212 search begins after RecA binds an initiating single-stranded DNA (ssDNA) in the primary DNA-binding s
217 advances in paleogenomics, we have applied a single-stranded DNA (ssDNA) library preparation method t
218 unwind double-stranded DNA (dsDNA) to reveal single-stranded DNA (ssDNA) needed for many biological p
219 old nanoparticles (GNPs) self-assembled with single-stranded DNA (ssDNA) of nheA gene immobilized wit
220 epsilon has greater contact with the nascent single-stranded DNA (ssDNA) of the leading strand on act
222 nerated DSB ends are processed to yield long single-stranded DNA (ssDNA) overhangs, which are quickly
225 her hand, BLM and RECQ5 demonstrated similar single-stranded DNA (ssDNA) reeling activities that were
226 f an archaeal MCM N-terminal domain bound to single-stranded DNA (ssDNA) revealed ssDNA associating a
227 totype hydrogel array which can analyze only single-stranded DNA (ssDNA) targets, the device is the f
228 t and the stronger interaction of SWNTs with single-stranded DNA (ssDNA) than double-stranded DNA (ds
229 te of cytosine deamination is much higher in single-stranded DNA (ssDNA) than in double-stranded DNA,
230 egy relies on the preferential adsorption of single-stranded DNA (ssDNA) to GO over aptamer-target co
232 tion and genomic substitution rates, RNA and single-stranded DNA (ssDNA) viruses may be important con
233 gle-stranded DNA binding protein (SSB) wraps single-stranded DNA (ssDNA) with high affinity to protec
234 (AFM) to show that Ver preferentially binds single-stranded DNA (ssDNA) with no sequence specificity
237 ate containing RNA:DNA hybrids and displaced single-stranded DNA (ssDNA), has emerged as a major sour
238 on of the DNA damage signal, accumulation of single-stranded DNA (ssDNA), sensitivity to replication
239 are factors that regulate the generation of single-stranded DNA (ssDNA), the enzymatic substrate of
240 rize the temperature-dependent elasticity of single-stranded DNA (ssDNA), where we find a significant
241 monly used recombinant AAV vectors contain a single-stranded DNA (ssDNA), which is transcriptionally
242 or the detections of metal ion, dopamine and single-stranded DNA (ssDNA), with detection limits of 1.
244 sitive coactivator of transcription (PC4), a single-stranded DNA (ssDNA)-binding protein, as a novel
252 PF and ERCC-XPF and show that the binding to single-stranded DNA (ssDNA)/dsDNA junctions is dependent
253 ch is able to detect hybridization of probe (single stranded DNA-ssDNA) and hybrid (double stranded D
255 rogrammability of DNA base pairing to direct single-stranded DNAs (ssDNAs) to assemble into desired 3
256 architectures of Watson-Crick complementary single-stranded DNA ("sticky end") linking strategies.
257 n alkaline solutions; whereas, the denatured single-stranded DNA strands readily reform duplexes at n
258 , AddAB or AdnAB) generates the requisite 3' single-strand DNA substrate for RecA-mediated strand inv
259 f neither non-compatible ends nor protruding single strand DNA sufficiently warranted the action of n
260 ese mutants compared with wild type DnaC for single-stranded DNA, suggesting that the substitutions a
262 is modulated by the nature of the 3'-ssDNA (single-stranded DNA) tail of the substrate and its effec
267 r displays good discrimination between three single-stranded DNA targets studied: fully complementary
268 gents, to prime second strand synthesis of a single-stranded DNA template and generate millions of pa
270 activation, overresection produces excessive single-stranded DNA that could lead to genomic instabili
271 rial strategies (1) , especially small lytic single-stranded DNA (the microviruses) and RNA phages (t
272 plification processing for the generation of single stranded DNA, thus presenting an assay that can f
273 re we report the use of intrinsically chiral single-stranded DNA to achieve simultaneous handedness a
276 D/APOBEC family enzymes convert cytosines in single-stranded DNA to uracils, causing base substitutio
278 hannel of the N-tier and the unwound leading single-strand DNA traverses the channel through the N-ti
280 rminal ATPase of MCM is compact and contacts single-stranded DNA, via a set of pre-sensor 1 hairpins
281 In the case of the ubiquitous human circular single-stranded DNA virus family Anelloviridae, there is
286 ore, the measurements of thermally denatured single-stranded DNA were carried out and the value of (G
289 uble-strand breaks creates long stretches of single-stranded DNA, which are rapidly bound by replicat
290 ecombination (HR) are first resected to form single-stranded DNA, which binds replication protein A (
291 e-stranded breaks that are processed to form single-stranded DNA, which can invade a homologous chrom
292 tides, called staple strands, to fold a long single-stranded DNA, which is called a scaffold strand,
293 sion of the DSB ends from double-stranded to single-stranded DNA, which is necessary to initiate DSB
294 an intrinsic preference for 5'-TC motifs in single-stranded DNA, which is the most frequently mutate
295 t preparations lacking DNA were able to bind single-stranded DNA with high affinity (Kd approximately
296 eir destinations allows for a simple robot a single-stranded DNA with one leg and two foot domains fo
297 different nucleic acids shows that it binds single-stranded DNA with three-fold lower affinity than
298 reaction (PER) cascades, which grow nascent single-stranded DNA with user-specified sequences follow
299 for deaminating cytosine bases to uracil in single-stranded DNA, with characteristic sequence prefer
300 Here, we present a study of surfactant and single-stranded DNA-wrapped SWNTs suspended in aqueous s
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