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1 affinity for RNA duplexes compared with the single strand RNA.
2 alone (apo) and in complex with a nonameric single-stranded RNA.
3 bits growth by sequence-specific cleavage of single-stranded RNA.
4 ng others responsible for the recognition of single-stranded RNA.
5 ding preferences of NPH-II for duplex versus single-stranded RNA.
6 esis is potently inhibited by the binding of single-stranded RNA.
7 equential packaging of its three segments of single-stranded RNA.
8 he respective RNA structures, and amounts of single-stranded RNA.
9 kinase is not activated by and does not bind single-stranded RNA.
10 age large, defined fragments of its genomic, single-stranded RNA.
11 replicative intermediate is represented by a single-stranded RNA.
12 ize the duplex by preferentially binding the single-stranded RNA.
13 ression and/or function of TLR7, a sensor of single-stranded RNA.
14 inding domain confers a general affinity for single-stranded RNA.
15 Argonaute-bound siRNA duplex is converted to single-stranded RNA.
16 the Grc3 kinase activity exclusively toward single-stranded RNA.
17 RNA and how this differs from its action on single-stranded RNA.
18 r by preventing the association of Dbp2 with single-stranded RNA.
19 are monomers that induce tight compaction of single-stranded RNA.
20 uble-stranded DNA, type III complexes target single-stranded RNA.
21 disposes of or processes viral and cellular single-stranded RNAs.
22 a segmented genome of eight negative-sense, single-stranded RNAs.
23 gher affinity to SL3 RNA than to double- and single-stranded RNAs.
24 tic Hen1 in their ability to methylate small single-stranded RNAs.
25 f these arises by Piwi-catalysed cleavage of single-stranded RNAs.
26 ressed the basic physical properties of long single-stranded RNAs.
27 the 5'-phosphate and 3'-hydroxyl termini of single-stranded RNAs.
28 the single-stranded DNA Microviridae and the single-stranded RNA Alloleviviridae, accomplish lysis by
30 xygen species, NOX2 oxidase, is activated by single stranded RNA and DNA viruses in endocytic compart
31 ows direct visualization of the encapsidated single-stranded RNA and coat protein (CP) N-terminal reg
32 rocessive DExH group often translocate along single-stranded RNA and displace paired strands (or prot
33 he pre-steady-state P(i) release kinetics on single-stranded RNA and DNA substrates of different leng
36 rified human PRC2 recognizes G > C,U >> A in single-stranded RNA and has a high affinity for folded g
37 ct sensitivity to pyrimidine-rich regions of single-stranded RNA and is able to process tRNA precurso
38 dered to be linked to the affinity of S1 for single-stranded RNA and its corresponding destabilizatio
39 association was dependent on the presence of single-stranded RNA and mediated by an N-terminal region
40 ts showed that both SUD-C and SUD-MC bind to single-stranded RNA and recognize purine bases more stro
42 and mutational analyses show how it threads single-stranded RNA, and structural features suggest how
43 x binds nucleic acids, with a preference for single-stranded RNA, and the Tex S1 domain is required f
46 itor the in vitro co-assembly of CCMV CP and single-stranded RNA as a function of the strength of CP-
47 ed and characterized two R-plasmid-dependent single-stranded RNA bacteriophages (RPD ssRNA phages), C
49 P L binding were blocked by preannealing the single-stranded RNA bait with miR-122, indicating that t
51 tion motif, domains are the largest class of single-stranded RNA binding domains in the human proteom
56 equence specifically to mRNA targets using a single-stranded RNA-binding domain comprising eight Pumi
58 his gene modifier screen identified EndoU, a single-stranded RNA-binding protein of ancient origin, a
60 binding miRNAs function as agonists of these single-stranded RNA-binding TLRs, leading to NF-kappaB s
62 that RNase BN is active on both double- and single-stranded RNA but that duplex RNA is preferred.
64 ed molecular patterns, including double- and single-stranded RNA, by pattern recognition receptors in
65 Top3beta is capable of converting two such single-stranded RNA circles into a double-stranded RNA c
66 olism, we designed an assay by annealing two single-stranded RNA circles with complementary sequences
68 an component has little or no influence over single-stranded RNA cleavage, RI evasion or cytotoxicity
69 response to cytosolic double-stranded RNA or single-stranded RNA containing 5'-triphosphate (5'-ppp).
70 ne motif to mediate high-affinity binding to single-stranded RNAs containing the transcriptional regu
74 Pase, one of the major enzymes with 3' to 5' single-stranded RNA degradation and processing activitie
76 the HIV-1 genome, which is in the form of a single-stranded RNA enclosed inside a capsid shell, must
79 West Nile virus (WNV), a mosquito-borne, single-stranded RNA flavivirus, causes significant human
81 S1 promotes RNA unwinding by binding to the single-stranded RNA formed transiently during the therma
83 l protocols, one involving direct capture of single-stranded RNA fragments and one involving circular
85 NA copying to proceed, while also protecting single-stranded RNA from Mg(2+)-catalyzed degradation.
86 ifferential scanning calorimetry showed that single-stranded RNA from satellite tobacco mosaic virus
87 nsation and found that ectopic expression of single-stranded RNAs from 1.688(X) repeats enhanced the
88 re critical for reverse transcription of the single-stranded RNA genome into double-stranded DNA.
90 s C, platelets replicated the positive sense single-stranded RNA genome of DENV by up to approximatel
91 talyses a series of reactions to convert the single-stranded RNA genome of HIV into double-stranded D
92 virus particles containing a negative-sense, single-stranded RNA genome packaged within a helical nuc
94 idae family of nonsegmented, negative-sense, single-stranded RNA genome viruses, is a leading cause o
98 ining feature of these viruses is that their single-stranded RNA genomes are of opposite polarity to
99 uses replicate by reverse transcribing their single-stranded RNA genomes into double-stranded DNA usi
103 ase, P4, uses chemical energy to translocate single-stranded RNA genomic precursors into the procapsi
106 iviral immune responses by recognizing viral single-stranded RNA in endosomes, but the biosynthetic p
108 rchange in the average probabilities to form single-stranded RNA in the optimal PPT and branch site l
109 al infections and cleaves cellular and viral single-stranded RNAs, including rRNAs in ribosomes.
111 Moreover, L-RNA complex formation depends on single-stranded RNA, indicating that inter-termini dsRNA
112 the transcription of the relatively flexible single-stranded RNA into a more rigid filamentous struct
115 l functional effects from a seemingly simple single-stranded RNA junction and suggest that junction s
117 with or without a 5'-triphosphate (ppp), by single-stranded RNA marked by a 5'-ppp and by polyuridin
118 e KWKK ((+)NH(3)-Lys-Trp-Lys-Lys-NH(2)) to a single-stranded RNA model, polyuridylate (polyU), by cha
121 As (miRNAs) are small (20-23 nt), non-coding single stranded RNA molecules that act as post-transcrip
122 ng a group of more than 1500 short noncoding single-strand RNA molecules of approximately 22 nucleoti
125 (CCMV) is capable of packaging both purified single-stranded RNA molecules of normal composition (com
126 inflammatory condition, is a class of short single-stranded RNA molecules termed microRNAs (miRNAs).
127 MicroRNAs (miRNAs) are naturally occurring single-stranded RNA molecules that post-transcriptionall
128 MicroRNAs (miRNAs) are a class of short single-stranded RNA molecules that posttranscriptionally
129 miRNAs are a class of 17- to 27-nucleotide single-stranded RNA molecules that regulate gene express
130 (miRNA) are a novel class of small noncoding single-stranded RNA molecules that regulate gene express
133 amer, whose interaction depended mainly on a single-stranded RNA motif, but not that of the GFP aptam
134 e junction between the stem and the flanking single-stranded RNA of the pri-miRNA hairpin by DGCR8 fo
135 se H activity that act in concert to convert single-stranded RNA of the viral genome to double-strand
137 es to study 3C alone and in complex with two single-stranded RNA oligonucleotides derived from the or
138 We also present modelling of pyrimidine-rich single-stranded RNA onto the highly conserved surface of
140 e RdRp can initiate de novo from the ends of single-stranded RNA or extend a primed RNA template.
141 8 may be activated by their native ligands, single-stranded RNA, or by small molecules of the imidaz
142 ther TLRs (poly(I.C), flagellin, loxoribine, single-stranded RNA, or CpG DNA) in macrophages and HEK-
143 viruses distantly related to members of the single-stranded RNA picorna-like virus superfamily were
146 ependent RNA endonuclease activity targeting single-stranded RNA regions and demonstrate the function
147 ome, we accurately and simultaneously mapped single-stranded RNA regions in multiple ncRNAs with know
151 ur NMR spectroscopic investigations on short single-stranded RNA revealed a strong preference for C2'
152 ssential host factor for many positive-sense single-stranded RNA (+RNA) viruses including human patho
156 A virus (IAV) genomes are composed of eight single-stranded RNA segments that are coated by viral nu
157 6) and identified two conserved, putatively single-stranded RNA segments, upstream of S1 (nt 2 and 3
159 s of Mss116p in complex with ATP analogs and single-stranded RNA show that the helicase core induces
161 serve that ATM silencing results in enhanced single-strand RNA (ssRNA) replication of RSVand Sendai v
164 Higher ratios of HCV double-stranded to single-stranded RNA (ssRNA) correlated positively with I
165 est Nile virus (WNV), a mosquito-transmitted single-stranded RNA (ssRNA) flavivirus, causes human dis
166 show that topological structures containing single-stranded RNA (ssRNA) free of strong base pairing
168 ata from a competition assay between SLA and single-stranded RNA (ssRNA) indicate that SLA competes w
169 ndicates that small phages, particularly the single-stranded RNA (ssRNA) leviviruses, have a previous
170 All RNA interference pathways use small single-stranded RNA (ssRNA) molecules that guide protein
171 A ligase to capture various short 20-24 base single-stranded RNA (ssRNA) oligonucleotides from a targ
173 The recent discovery of the positive-sense single-stranded RNA (ssRNA) Orsay virus (OV) as a natura
174 ose genome is packaged sequentially as three single-stranded RNA (ssRNA) segments into an icosahedral
175 ) binds with 20nM dissociation constant to a single-stranded RNA (ssRNA) sequence adjacent to the bra
176 d protein structures are the active sites of single-stranded RNA (ssRNA) synthesis; (v) at late times
177 e show that Cas9 binds with high affinity to single-stranded RNA (ssRNA) targets matching the Cas9-as
178 ed rotavirus double-layer particles, nascent single-stranded RNA (ssRNA) transcripts (termed in vitro
179 ontal gene transfer may have occurred from a single-stranded RNA (ssRNA) virus (hypovirus) to a dsRNA
180 ly for adenoviruses, which resembles that of single-stranded RNA (ssRNA) viruses but differs from the
183 h pump their genome into a preformed capsid, single-stranded RNA (ssRNA) viruses, such as bacteriopha
185 en the rates of double-stranded DNA (dsDNA), single-stranded RNA (ssRNA), and ssDNA/reverse-transcrib
186 recognizes guanosine- and uridine-rich viral single-stranded RNA (ssRNA), including influenza virus s
187 zyme Argonaute 2 (hAgo2) and Cryptosporidium single-stranded RNA (ssRNA), we induced specific slicing
188 x measures either ~22 nt from the upper stem-single-stranded RNA (ssRNA, terminal loop) junction or ~
189 ruses, especially those with positive-sense, single-stranded RNA (+ssRNA) genomes, are abundant in tr
190 important roles in inhibiting positive-sense single-stranded RNA (+ssRNA) viral infection, especially
192 CCHF) virus is a tick-borne, negative-sense, single-stranded RNA [ssRNA(-)] nairovirus that produces
193 sent in all three pathogenic positive-sense, single-stranded RNA [(+)ssRNA] virus families which carr
194 cinating features of these highly structured single stranded RNAs (ssRNAs) with emphasis on their pre
196 Chemical shift changes upon the addition of single-stranded RNAs (ssRNAs) identified a group of resi
197 bstantially higher affinity as compared with single-stranded RNA structures unless they contain a 5'-
198 w that Rho unidirectionally translocates the single-stranded RNA substrate via a population shift of
200 minus resemble those seen in the presence of single-stranded RNA suggesting similarities in binding.
201 signaling induced by NOD2 over-expression or single stranded RNA, suggesting specificity for the MDP-
202 Ape1 was found to cleave AP-site-containing single-stranded RNA, suggesting a novel "cleansing" func
203 strand scission in double-stranded RNA over single-stranded RNA suggests that this chemistry may be
204 lex RNA regardless of the orientation of the single-stranded RNA tail, it preferred a 5' to 3' polari
205 e CRISPR RNA and can be programmed to cleave single-stranded RNA targets carrying complementary proto
206 a unique biochemical activity: the use of a single-stranded RNA template for the synthesis of single
207 es the ability of VP1 to replicate synthetic single-stranded RNA templates containing the 3' untransl
211 roRNAs (miRNAs) are small approximately 22nt single stranded RNAs that negatively regulate protein ex
215 NAs (miRNAs) are 19 to 25nt non-coding small single-stranded RNAs that negatively regulate gene expre
217 unusually long, high-affinity interface with single-stranded RNA, that this interface provides a func
218 e also show that TRBP can bind 21-nucleotide single-stranded RNAs, though with far lower affinity tha
219 lex dynamics associated with transition of a single stranded RNA to its secondary and tertiary struct
220 atalyzes intramolecular ligation of 5'-PO(4) single-strand RNA to form a covalently closed circular R
221 capsidation and reverse transcription from a single-stranded RNA to a double-stranded DNA through the
222 MthRnl) catalyzes intramolecular ligation of single-stranded RNA to form a closed circular RNA via co
223 ay represent a conserved scaffold that binds single-stranded RNA to regulate transcription in both eu
225 ed by the complementary association of three single-stranded RNA units, was optimized for improved ge
226 with 10-bp RNA-RNA duplexes and was aided by single-stranded RNA upstream of the duplex but was signi
227 he strength of attraction between CP and the single-stranded RNA viral genome is controlled by ionic
232 arainfluenza virus (PIV) is a negative-sense single-stranded RNA virus in the Paramyxoviridae family.
233 xin (EMR) family have been shown to modulate single-stranded RNA virus infection through regulating s
234 netics and mechanisms of inactivation of the single-stranded RNA virus MS2 under temperature, pH and
235 ect experimental evidence that assembly of a single-stranded RNA virus occurs via a packaging signal-
236 amyxovirus type 1 (APMV-1), a negative-sense single-stranded RNA virus of the genus Avulavirus, famil
237 ry syncytial virus (RSV) is a negative-sense single-stranded RNA virus responsible for lower respirat
238 ry syncytial virus (RSV) is a negative-sense single-stranded RNA virus responsible for lower respirat
239 Human respiratory syncytial virus (RSV) is a single-stranded RNA virus that causes acute, and occasio
241 d the RNA content of a purified nonenveloped single-stranded RNA virus, flock house virus (FHV).
246 or the replication of various positive-sense single stranded RNA viruses, which hijack this cellular
247 stroviruses are nonenveloped, positive-sense single-strand RNA viruses associated with self-limiting
250 r mechanisms controlling genome packaging by single-stranded RNA viruses are still largely unknown.
252 n is a common strategy among positive-sense, single-stranded RNA viruses for bypassing the host cell
254 he members of this family of positive-sense, single-stranded RNA viruses have limited coding capacity
256 potentially profound implications for other single-stranded RNA viruses known to have RNA PSs, inclu
257 that the screened ISGs target positive-sense single-stranded RNA viruses more effectively than negati
262 eny, experimental evidence on positive sense single-stranded RNA viruses suggests that the CP also re
263 ain evolutionary dynamics closer to those of single-stranded RNA viruses than to those of double-stra
264 y of enveloped, negative-sense, nonsegmented single-stranded RNA viruses that account for a significa
265 s (HAstVs) are nonenveloped, positive-sense, single-stranded RNA viruses that are a leading cause of
269 stroviruses are nonenveloped, positive-sense single-stranded RNA viruses that cause gastrointestinal
271 link between platelets and their response to single-stranded RNA viruses that involves activation of
273 a large family of enveloped, negative-sense, single-stranded RNA viruses with significant economic an
274 double-stranded RNA viruses, positive-sense single-stranded RNA viruses, and the reverse-transcribin
275 hibit the replication of many negative-sense single-stranded RNA viruses, as well as double-stranded
276 We found that during sickness behavior, single-stranded RNA viruses, double-stranded RNA ligands
278 Alphavirus consists of a group of enveloped, single-stranded RNA viruses, many of which are transmitt
279 ation of selected nonenveloped and enveloped single-stranded RNA viruses, retroviruses, bacteriophage
280 ve roles of viral genomes in the assembly of single-stranded RNA viruses, we have developed a new ana
288 small, spherical, enveloped, positive-sense, single-stranded, RNA viruses responsible for considerabl
289 efective in signaling with triphosphorylated single-stranded RNAs were perfectly capable of signaling
290 structural homology, wild-type MAB21L2 bound single-stranded RNA, whereas this activity was lost in a
292 roaches for estimating hydrodynamic radii of single-stranded RNAs, which use generic RNA structure pr
294 c SAMHD1 was found to bind preferentially to single-stranded RNA, while the tetrameric form required
295 receptors (RLRs), RIG-I and MDA5, recognize single-stranded RNA with 5' triphosphates and double-str
297 The influenza virus genome is an 8-segment single-stranded RNA with high potential for in situ reco
299 It displays unusual specificity in vitro for single-stranded RNAs with at least one adenosine at the
300 is triggered by either single strand DNA or single strand RNA, yet the apparent affinity for a DNA a
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