ライフサイエンスコーパス: single-stranded

1 ngth, and T. brucei telomeres terminate in a single-stranded 3' G-rich overhang.

2 nique ribonuclease activity that cleaves the single-stranded 3'-end from tRNAs that contain guanine d

3 We infused a single-stranded adeno-associated viral (AAV) vector cons

4 We found a 60:40 ratio of double- and single-stranded alpha-helix in the highly rigid hydrogel

5 o activities of 1, 2 and 3 GalNAc conjugated single stranded and duplexed ASOs were studied.

6 but also reporter gene expression from both single-stranded and double-stranded (self-complementary)

7 -alkylguanine and O4-alkylthymine adducts in single-stranded and duplex DNAs.

8 between the empty and full capsids for both single-stranded and self-complementary AAV vectors indic

9 ew amplicons despite the theoretical lack of single-stranded annealing sites.

10 Two and three GalNAc conjugated single stranded ASOs bind the ASGR with the strongest af

11 ound in both double-stranded (symmetric) and single-stranded (asymmetric) genomic contexts.

12 Single-stranded azide-labelled DNA was conveniently prep

13 Uncovering the mechanisms by which single-stranded binding proteins both protect and expose

14 etermined the kinetics and thermodynamics of single-stranded break ligation by LIG3alpha and LIG3beta

15 umerically study the thermal conductivity of single-stranded carbon-chain polymers with multiple subs

16 Under optimised sensing conditions, the single stranded CCCVd RNA oligonucleotide target could b

17 obases at 37 degrees C from both double- and single-stranded circular template DNA using specific pri

18 "Blunt-ended" tiles do not have single-stranded complementary ends, and thus instead of

19 e detected for the telomere repeat TTAGGG in single-stranded configuration, showing that secondary st

20 de experimental evidence that ComFA binds to single stranded DNA (ssDNA) and has ssDNA-dependent ATPa

21 ipment and facilitates the immobilization of single stranded DNA (ssDNA) probe sequences on a wide va

22 zyme which selectively digests the 3'-end of single stranded DNA (ssDNA).

23 ed through pH-assisted thiol-gold bonding of single stranded DNA and salt aging, with preconjugated b

24 telomeric G-quadruplex DNA to complementary single stranded DNA and to telomere binding protein POT1

25 An amino-modified single stranded DNA oligonucleotide probe synthesised ba

26 ped AuNPs and the d-AuNPs were stabilized by single stranded DNA probe (ssDNAp).

27 which is able to detect the hybridization of single stranded DNA probe with its complementary target

28 stranded MLPA products and subsequently to a single stranded DNA reporter probe bearing a HRP molecul

29 ch is able to detect hybridization of probe (single stranded DNA-ssDNA) and hybrid (double stranded D

30 s, as well as numerous circular Rep-encoding single-stranded DNA (CRESS DNA) viral genomes, were iden

31 mbination of alternating double-stranded and single-stranded DNA (dsDNA and ssDNA) regions of varying

32 RPA-coated single-stranded DNA (RPA-ssDNA), a nucleoprotein structu

33 ich forms helical nucleoprotein filaments on single-stranded DNA (ssDNA) and catalyzes strand invasio

34 ate-free synthesis of high-molecular-weight, single-stranded DNA (ssDNA) and demonstrate that it proc

35 nnealase, a protein that binds complementary single-stranded DNA (ssDNA) and facilitates its annealin

36 A orchestrates these processes by binding to single-stranded DNA (ssDNA) and interacting with several

37 Human RAD52 has been shown to mediate single-stranded DNA (ssDNA) and is synthetic lethal with

38 Single-stranded DNA (ssDNA) and RNA regions that include

39 The bacterial single-stranded DNA (ssDNA) binding protein SSB is a str

40 The 2 single-stranded DNA (ssDNA) binding proteins SSB1 and SS

41 The single-stranded DNA (ssDNA) cytidine deaminase APOBEC3F

42 The APOBEC3B (A3B) single-stranded DNA (ssDNA) cytosine deaminase has impor

43 By rationally designing single-stranded DNA (ssDNA) donors of the optimal length

44 NA repair restores the resulting 5'-Flap and single-stranded DNA (ssDNA) gap.

45 through the cell cytoplasm, and deliver the single-stranded DNA (ssDNA) genome to the nucleus, where

46 n genome maintenance, binding and organizing single-stranded DNA (ssDNA) intermediates.

47 Single-stranded DNA (ssDNA) is notable for its interacti

48 epsilon has greater contact with the nascent single-stranded DNA (ssDNA) of the leading strand on act

49 nerated DSB ends are processed to yield long single-stranded DNA (ssDNA) overhangs, which are quickly

50 her hand, BLM and RECQ5 demonstrated similar single-stranded DNA (ssDNA) reeling activities that were

51 te of cytosine deamination is much higher in single-stranded DNA (ssDNA) than in double-stranded DNA,

52 egy relies on the preferential adsorption of single-stranded DNA (ssDNA) to GO over aptamer-target co

53 ons or by template-directed synthesis with a single-stranded DNA (ssDNA) topological structure.

54 tion and genomic substitution rates, RNA and single-stranded DNA (ssDNA) viruses may be important con

55 gle-stranded DNA binding protein (SSB) wraps single-stranded DNA (ssDNA) with high affinity to protec

56 (AFM) to show that Ver preferentially binds single-stranded DNA (ssDNA) with no sequence specificity

57 ate containing RNA:DNA hybrids and displaced single-stranded DNA (ssDNA), has emerged as a major sour

58 on of the DNA damage signal, accumulation of single-stranded DNA (ssDNA), sensitivity to replication

59 or the detections of metal ion, dopamine and single-stranded DNA (ssDNA), with detection limits of 1.

60 sitive coactivator of transcription (PC4), a single-stranded DNA (ssDNA)-binding protein, as a novel

61 Strikingly, the addition of the single-stranded DNA (ssDNA)-binding replication protein

62 rand synthesis leads to accumulation of long single-stranded DNA (ssDNA).

63 sive processing, producing long stretches of single-stranded DNA (ssDNA).

64 ly 2 helicase Hel308 during translocation on single-stranded DNA (ssDNA).

65 PF and ERCC-XPF and show that the binding to single-stranded DNA (ssDNA)/dsDNA junctions is dependent

66 rial strategies (1) , especially small lytic single-stranded DNA (the microviruses) and RNA phages (t

67 The microbial target, single-stranded DNA amplified with asymmetric PCR, was q

68 lyzed, radical reaction process that cleaves single-stranded DNA and requires only redox-inactive met

69 nzymes, dimerization enables processivity on single-stranded DNA and results in higher levels of muta

70 e and reveals new interactions between short single-stranded DNA and the vestibule of a biological po

71 exed, expanded proteomic technique that uses single-stranded DNA aptamers to assay 4783 human protein

72 RNA or single-stranded DNA aptamers with 2'-F pyrimidines have

73 hods for autonomously synthesizing arbitrary single-stranded DNA are limited.

74 iring lesions using double-stranded, but not single-stranded DNA as a template.

75 Here the authors show that APOBEC3G binds single-stranded DNA as an active deaminase monomer, subs

76 We have investigated the dynamics of single-stranded DNA as it translocates through charge-mu

77 nthetic sequence that mimics freshly unwound single-stranded DNA at replication fork showed that RPA

78 when recombinantly expressed had the general single-stranded DNA binding activity of RPA complexes, u

79 Here we measure the single-stranded DNA binding and oligomerization kinetics

80 ralogous to the large subunit of the general single-stranded DNA binding heterotrimer replication pro

81 The bacterial single-stranded DNA binding protein (SSB) acts as an org

82 The single-stranded DNA binding protein (SSB) of Escherichia

83 During DNA replication, the single-stranded DNA binding protein (SSB) wraps single-s

84 The nascent DNA colocalized with the VACV single-stranded DNA binding protein I3 in multiple punct

85 The T7 single-stranded DNA binding protein increases primer for

86 lymerase gamma holoenzyme, the mitochondrial single-stranded DNA binding protein mtSSB, the replicati

87 factor IIH prevented the accumulation of the single-stranded DNA binding protein replication protein

88 hairpin RNA (shRNA) screening, we identified single-stranded DNA binding protein replication protein

89 loader, the PCNA sliding clamp, and the RPA single-stranded DNA binding protein.

90 und by replication protein A (RPA) and other single-stranded DNA binding proteins (SSBs).

91 These results reveal the role of single-stranded DNA binding proteins in controlling Exo1

92 ains to distinguish the PriA interaction and single-stranded DNA binding.

93 Human APOBEC3H and homologous single-stranded DNA cytosine deaminases are unique to ma

94 APOBEC3s (A3s) are single-stranded DNA cytosine deaminases that provide inn

95 -CRISPR), a targeting strategy in which long single-stranded DNA donors are injected with pre-assembl

96 A double-strand breaks (DSBs) to generate 3'-single-stranded DNA facilitates DSB repair via error-fre

97 The separation and partitioning of large single-stranded DNA fragments of the homologous chromoso

98 We demonstrated that Brca2 protein prevents single-stranded DNA gap accumulation at replication fork

99 tions arise through the aberrant repair of a single-stranded DNA gap, in a process that is dependent

100 RarA ATPase activity is stimulated by single-stranded DNA gaps and double-stranded DNA ends.

101 orporates ribonucleotides and/or accumulates single-stranded DNA gaps during replication.

102 phosphate, and also for cytosine residues in single-stranded DNA generated from a phagemid, in which

103 determine how they contribute to duplex and single-stranded DNA handling, and test the cellular cons

104 ded binding proteins both protect and expose single-stranded DNA has important implications for our u

105 uble-stranded DNA in its ATP-bound state and single-stranded DNA in its apo state.

106 unequivocally establishes the existence of a single-stranded DNA incorporation pathway in human cells

107 zes synthesis-dependent strand annealing and single-stranded DNA incorporation pathways.

108 ude that ROS contribute to TLD by converting single-stranded DNA lesions into double-stranded DNA bre

109 NA hybridized to the complementary DNA and a single-stranded DNA loop, are formed in switch regions o

110 Our data suggests that single-stranded DNA molecules may influence DNA junction

111 pose that these contigs correspond to linear single-stranded DNA molecules that fold onto themselves

112 ate recombination (SPDIR), facilitates short single-stranded DNA molecules to invade and replace geno

113 olecule arrays by electrostatically adhering single-stranded DNA of gene-like length onto positively

114 ce receptor of interest is conjugated with a single-stranded DNA oligonucleotide, which hybridizes to

115 tutions via HDR following co-delivery with a single-stranded DNA oligonucleotide.

116 Single-stranded DNA oligonucleotides have unique, and in

117 ins for Proteomics) is an approach that uses single-stranded DNA oligonucleotides to capture specific

118 and diffusion constants of several different single-stranded DNA oligonucleotides trapped in an MspA

119 hydrolysis, although they both cleave simple single-stranded DNA oligonucleotides.

120 fficient covalent immobilization of purified single-stranded DNA probe oligomers on cleaned gold micr

121 ine starvation leads to accumulation of both single-stranded DNA regions and intracellular ROS, and i

122 ivery of CRISPR/Cpf1 ribonucleoproteins with single-stranded DNA repair templates results in precise

123 nd resection, which generates long tracts of single-stranded DNA required for checkpoint activation a

124 We have screened over 300 short single-stranded DNA sequences with palindrome symmetry,

125 High-throughput single-stranded DNA sequencing (ssDNA-seq) of cell-free

126 ollowed by resection to generate invasive 3' single-stranded DNA tails.

127 gents, to prime second strand synthesis of a single-stranded DNA template and generate millions of pa

128 d both must remodel onto opposite strands of single-stranded DNA to do so.

129 D/APOBEC family enzymes convert cytosines in single-stranded DNA to uracils, causing base substitutio

130 In the case of the ubiquitous human circular single-stranded DNA virus family Anelloviridae, there is

131 Circular single-stranded DNA viruses infect archaea, bacteria, an

132 The relatively recent emergence of single-stranded DNA viruses, such as chicken anemia viru

133 o reach up to 22 hours, whereas unconjugated single-stranded DNA was degraded within minutes.

134 ore, the measurements of thermally denatured single-stranded DNA were carried out and the value of (G

135 Elevated levels of single-stranded DNA were necessary but insufficient for

136 eir destinations allows for a simple robot a single-stranded DNA with one leg and two foot domains fo

137 reaction (PER) cascades, which grow nascent single-stranded DNA with user-specified sequences follow

138 tional R-loops (RNA/DNA duplex and displaced single-stranded DNA) and DNA double-strand breaks (DSBs)

139 on associated with increased accumulation of single-stranded DNA, a substrate of APOBEC3A, triggering

140 bustly with specific sequences of unmodified single-stranded DNA, and we have identified five tags th

141 an essential replisome component that binds single-stranded DNA, has a role in replication-coupled n

142 sequence, the proteinosome payload (dextran, single-stranded DNA, platinum nanoparticles) is traffick

143 ese mutants compared with wild type DnaC for single-stranded DNA, suggesting that the substitutions a

144 rminal ATPase of MCM is compact and contacts single-stranded DNA, via a set of pre-sensor 1 hairpins

145 uble-strand breaks creates long stretches of single-stranded DNA, which are rapidly bound by replicat

146 tides, called staple strands, to fold a long single-stranded DNA, which is called a scaffold strand,

147 for deaminating cytosine bases to uracil in single-stranded DNA, with characteristic sequence prefer

148 ethods, this amplification requires only the single-stranded DNA-binding protein gp32 from bacterioph

149 nal proteins, including the telomeric repeat single-stranded DNA-binding protein Teb1 and its heterot

150 The replication protein A (RPA) is a single-stranded DNA-binding protein that plays an essent

151 Single-stranded DNA-binding proteins (SSBs) play a key r

152 d of telomeric sequence-specific double- and single-stranded DNA-binding proteins, Taz1 and Pot1, res

153 Here, we present a study of surfactant and single-stranded DNA-wrapped SWNTs suspended in aqueous s

154 ation of transcription from both double- and single-stranded DNA.

155 First, we modified a glass surface with single-stranded DNA.

156 ish this task, RAD51 must be loaded onto the single-stranded DNA.

157 yed as the redox indicator binding better to single-stranded DNA.

158 s comprise an RNA/DNA hybrid and a displaced single-stranded DNA.

159 hrough deaminating cytosine (C) to uracil on single-stranded DNA/RNA.

160 nctionalized and codified with two different single stranded-DNA (ssDNA) chains.

161 We recently demonstrated that long single-stranded DNAs (ssDNAs) serve as very efficient do

162 We found that XPA binds different single-stranded/double-stranded junction DNA substrates

163 tedly that PGL-1 DD is a guanosine-specific, single-stranded endonuclease.

164 s comprised of double-stranded DNA with a 3' single-stranded extension.

165 1 (hFEN1) catalyzes the essential removal of single-stranded flaps arising at DNA junctions during re

166 delocalized phonon-like modes in DNA provide single-stranded "flexible hinges" to assist in loop form

167 processing nucleases, in order to close the single-stranded gap and terminate further resection.

168 We also identify single-stranded gaps as plausible deletion precursors, p

169 ble-stranded DNA breaks (SSBs and DSBs), and single-stranded gaps can block progression of the DNA re

170 ite having vastly different propensities for single-stranded helical stacking.

171 thod employs molecular beacons (MBs) and two single-stranded helper DNA probes.

172 sulting in the exposure of long stretches of single-stranded leading-strand template.

173 This method combines an ultra-sensitive single-stranded library construction with barcoding erro

174 cing System of Digitalized Barcode Encrypted Single-stranded Library from Extremely Low (quality and

175 tructures (duplex, hairpin, G-quadruplex and single-stranded), ligand types (ion, small organic molec

176 stabilized by specific insertion of a short single-stranded linker.

177 ate that introducing anti-GAA duplex RNAs or single-stranded locked nucleic acids into patient-derive

178 Single-stranded miRNAs inhibitors were used to block sel

179 manufactured electrode array and exposed to single-stranded MLPA products and subsequently to a sing

180 tem is composed of two nanoconjugates: (1) a single-stranded morpholino oligonucleotide (MORF1) attac

181 Alternatively, hUPF1 binds to single-stranded NAs (ssNA) with apparent affinity increa

182 Mononegaviruses have non-segmented, single-stranded negative-sense RNA genomes that are enca

183 signal (a hemi-methylated d(GATC) site or a single-stranded nick) and the replication error after th

184 avirales is composed of viruses that possess single-stranded, non-segmented negative-sense (NNS) RNA

185 spindle tuber viroid (PSTVd) is a circular, single-stranded, noncoding RNA plant pathogen that is a

186 Single-stranded nucleic acids (ssNAs) are ubiquitous in

187 semble of flexible polyelectrolytes, such as single-stranded nucleic acids (ssNAs), is complicated by

188 tic domain (CD2) alone is capable of binding single-stranded nucleic acids and is important for deami

189 ltaneously structures formed from regulatory single-stranded nucleic acids are stabilized.

190 to enable them to bind a variable number of single-stranded nucleotides depending on the salt and pr

191 a CRISPR plasmid expressing Cas9/gRNA and a single-stranded oligodeoxynucleotide HDR donor template

192 ization of FOXO protein via CRISPR-assisted, single-stranded oligodeoxynucleotide-mediated homology-d

193 ADAPT employs an enriched library of single-stranded oligodeoxynucleotides (ssODNs) to profil

194 urrent article, we demonstrate that RNAs and single-stranded oligonucleotide analogs, or xeno nucleic

195 een restricted to using invasive intrathecal single-stranded oligonucleotide delivery.

196 onversion with either double-stranded DNA or single-stranded oligonucleotide donors by up to 5.6-fold

197 DNA logic gate circuits typically provide a single-stranded oligonucleotide output, limiting the abi

198 and internalization of highly polar anionic single stranded oligonucleotides into cells and tissues.

199 precision genome editing in plants that uses single-stranded oligonucleotides (ssODNs) to precisely a

200 Because of difficulties of delivering single-stranded oligonucleotides to the CNS, current app

201 d this pattern held true whether the DNA was single-stranded or duplex.

202 strate recognition by capturing two adjacent single-stranded overhangs simultaneously.

203 In piRNA biogenesis, single-stranded piRNA intermediates are loaded into PIWI

204 Hepatitis C virus (HCV) is a single-stranded positive-sense RNA hepatotropic virus.

205 Hepatitis E virus (HEV), a single-stranded positive-sense RNA virus, generally caus

206 Fluorescently labeled single stranded probe strands and graphene oxide nanoass

207 sively copied, and regenerated by release of single-stranded product DNA.

208 ransduced by the double-stranded but not the single-stranded recombinant AAV2 vectors progressed thro

209 unds, and that motifs are found in a loop or single stranded region of the potential RNA secondary st

210 e many different aspects of RNA ranging from single stranded regions to discrete secondary or tertiar

211 Single-stranded regions in such RNAs contribute to bindi

212 expressed COL1A gene, and co-injected with a single-stranded repair template into porcine zygotes.

213 xygen species, NOX2 oxidase, is activated by single stranded RNA and DNA viruses in endocytic compart

214 or the replication of various positive-sense single stranded RNA viruses, which hijack this cellular

215 ate that M. tuberculosis RpsA interacts with single stranded RNA, but not with POA.

216 ssential host factor for many positive-sense single-stranded RNA (+RNA) viruses including human patho

217 important roles in inhibiting positive-sense single-stranded RNA (+ssRNA) viral infection, especially

218 Higher ratios of HCV double-stranded to single-stranded RNA (ssRNA) correlated positively with I

219 show that topological structures containing single-stranded RNA (ssRNA) free of strong base pairing

220 ata from a competition assay between SLA and single-stranded RNA (ssRNA) indicate that SLA competes w

221 ndicates that small phages, particularly the single-stranded RNA (ssRNA) leviviruses, have a previous

222 The recent discovery of the positive-sense single-stranded RNA (ssRNA) Orsay virus (OV) as a natura

223 ly for adenoviruses, which resembles that of single-stranded RNA (ssRNA) viruses but differs from the

224 h pump their genome into a preformed capsid, single-stranded RNA (ssRNA) viruses, such as bacteriopha

225 rified human PRC2 recognizes G > C,U >> A in single-stranded RNA and has a high affinity for folded g

226 In single-stranded RNA bacteriophages (ssRNA phages) a sing

227 tion motif, domains are the largest class of single-stranded RNA binding domains in the human proteom

228 s a protein conformational change induced by single-stranded RNA binding.

229 tion that is distinct from its RNA-activated single-stranded RNA degradation activity.

230 the HIV-1 genome, which is in the form of a single-stranded RNA enclosed inside a capsid shell, must

231 The virus possesses a negative-sense single-stranded RNA genome of approximately 13.3 kb enca

232 nonenveloped icosahedral virions containing single-stranded RNA genomes.

233 the transcription of the relatively flexible single-stranded RNA into a more rigid filamentous struct

234 70) is a demethylase that removes m(6)A from single-stranded RNA molecules in vitro.

235 (CCMV) is capable of packaging both purified single-stranded RNA molecules of normal composition (com

236 se H activity that act in concert to convert single-stranded RNA of the viral genome to double-strand

237 Aptamers are single-stranded RNA or DNA molecules that have recently

238 A virus (IAV) genomes are composed of eight single-stranded RNA segments that are coated by viral nu

239 lex RNA regardless of the orientation of the single-stranded RNA tail, it preferred a 5' to 3' polari

240 e CRISPR RNA and can be programmed to cleave single-stranded RNA targets carrying complementary proto

241 MthRnl) catalyzes intramolecular ligation of single-stranded RNA to form a closed circular RNA via co

242 Previously, a stochastic model of single-stranded RNA virus assembly was created to model

243 arainfluenza virus (PIV) is a negative-sense single-stranded RNA virus in the Paramyxoviridae family.

244 With Coxsackievirus B3 (CVB3) being a single-stranded RNA virus, and the recent evidence that

245 n is a common strategy among positive-sense, single-stranded RNA viruses for bypassing the host cell

246 Flaviviruses are positive-sense, single-stranded RNA viruses responsible for millions of

247 stroviruses are nonenveloped, positive-sense single-stranded RNA viruses that cause gastrointestinal

248 a large family of enveloped, negative-sense, single-stranded RNA viruses with significant economic an

249 We found that during sickness behavior, single-stranded RNA viruses, double-stranded RNA ligands

250 ity of identified viruses are positive-sense single-stranded RNA viruses.

251 DNA data is transcribed into single-stranded RNA, which folds into specific molecular

252 ng others responsible for the recognition of single-stranded RNA.

253 esis is potently inhibited by the binding of single-stranded RNA.

254 kinase is not activated by and does not bind single-stranded RNA.

255 the Grc3 kinase activity exclusively toward single-stranded RNA.

256 RNA and how this differs from its action on single-stranded RNA.

257 Single-stranded RNAs also activate PKR constructs lackin

258 Here, we demonstrate that single-stranded RNAs bind to PKR with micromolar dissoci

259 On the other hand, Cap-0 and 5'ppp single-stranded RNAs did not bind RIG-I and are signalin

260 Circular RNAs (circRNAs) are single-stranded RNAs that are joined head to tail with l

261 ressed the basic physical properties of long single-stranded RNAs.

262 the 5'-phosphate and 3'-hydroxyl termini of single-stranded RNAs.

263 of a uridine two nucleotides downstream in a single-stranded segment, which we rationalize structural

264 ically binding the terminal loop near the 3' single-stranded segment.

265 active as nucleoprotein filaments formed on single-stranded segments of DNA.

266 we report a method, which is dubbed SISSOR (single-stranded sequencing using microfluidic reactors),

267 sequence the three-dimensional structures of single stranded (ss) DNA required for aptamer applicatio

268 FEN1 precisely cleaves single-stranded (ss) 5'-flaps one nucleotide into duplex

269 lular RNAs inhibits A3G binding to substrate single-stranded (ss) DNA and CDA activity.

270 Gene 32 protein (gp32) is the single-stranded (ss) DNA binding protein of the bacterio

271 y critical roles in controlling infection of single-stranded (ss) DNA geminiviruses and ssRNA viroids

272 at an icosahedral fivefold vertex and induce single-stranded (ss) DNA genome ejection.

273 DNA replication forks generates stretches of single-stranded (ss) DNA on both strands that are expose

274 Such studies often embed a single-stranded (ss) DNA region within a longer double-s

275 of these activities is its ATP-driven 3'-5' single-stranded (ss) DNA translocation activity.

276 RAD51 first forms a presynaptic filament on single-stranded (ss) DNA, which catalyses pairing with h

277 eless preserve closed circular DNA in either single-stranded (SS) or double-stranded (DS) form.

278 for the first time, the interaction of long single-stranded (ss) RNAs with cognate homologous double

279 Single-stranded (ss)DNA binding (SSB) proteins bind with

280 We have established single-stranded (ss)DNA curtain assays for measuring ind

281 ch we find to be similar to that of the pure single-stranded state.

282 perimentally construct diverse multikilobase single-stranded structures, including a 10,000-nucleoti

283 mportant for the processing of DNA ends into single-stranded substrates for homologous recombination.

284 lization of CpG oligodeoxynucleotide 1826, a single-stranded synthetic DNA adjuvant, eliciting an enh

285 r, G4-T-oligo has similar cellular uptake as single-stranded T-oligo, as shown by FACS analysis.

286 ased antiproliferative effects compared with single-stranded T-oligo.

287 G4-T-oligo was found to be more stable than single-stranded T-oligo.

288 riggers the consumption of fuel strands with single-stranded tails for HCR.

289 piezophila Argonaute (MpAgo) protein cleaves single-stranded target sequences using 5'-hydroxylated g

290 cific proteins that bind as a heterodimer to single-stranded telomere DNA to prevent illicit DNA dama

291 With the exception of the single-stranded telomeric DNA, all genomic G-rich sequen

292 c mutations in hPOT1 OB-fold fail to bind to single-stranded telomeric DNA, eliciting a DNA damage re

293 lted out into a transcription bubble and the single-stranded template DNA is delivered to the RNAP ac

294 leolytic resection of DNA ends to generate a single-stranded template for the recruitment of another

295 NAP-promoter open complex (RPo) containing a single-stranded transcription bubble, and selects a temp

296 NAP-promoter open complex (RPo) containing a single-stranded 'transcription bubble,' and selects a tr

297 sylase that only acts on double-stranded and single-stranded uracil-containing DNA.

298 signature sequence, a GAUC repeat framed by single-stranded uridines.

299 Here, we created site-specifically modified single-stranded vectors for replication in primate (COS7

300 The viruses, all positive sense single-stranded, were classified into diverse orders/fam

301 Experimentally, a single-stranded zig-zag chain of phosphorus atoms was ob