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   1      First, we modified a glass surface with single-stranded DNA.                                    
     2 ish this task, RAD51 must be loaded onto the single-stranded DNA.                                    
     3 yed as the redox indicator binding better to single-stranded DNA.                                    
     4  as the experimental approaches used to pull single-stranded DNA.                                    
     5 een the unwinding substrate and a homologous single-stranded DNA.                                    
     6 of the MCM work in concert to translocate on single-stranded DNA.                                    
     7 mplex that is required for loading DnaB onto single-stranded DNA.                                    
     8 ' oriented laying out of hRPA subunits along single-stranded DNA.                                    
     9 ated NPH I acts as a 5' to 3' translocase on single-stranded DNA.                                    
    10 ction, via its BRCT2 domain, with RPA-coated single-stranded DNA.                                    
    11 asize the lesser-known elastic properties of single-stranded DNA.                                    
    12 igh levels of hyperphosphorylated RPA-loaded single-stranded DNA.                                    
    13 1 protease is accelerated in the presence of single-stranded DNA.                                    
    14 d magnetic beads and macromolecular coils of single-stranded DNA.                                    
    15  ATPase activity of MtRecD was stimulated by single-stranded DNA.                                    
    16 rameters resembling enzymes translocating on single-stranded DNA.                                    
    17 bound to a parallel quadruplex compared with single-stranded DNA.                                    
    18 e that informs a multistep model for binding single-stranded DNA.                                    
    19 s comprise an RNA/DNA hybrid and a displaced single-stranded DNA.                                    
    20 ation of transcription from both double- and single-stranded DNA.                                    
    21 on associated with increased accumulation of single-stranded DNA, a substrate of APOBEC3A, triggering
  
    23 CNA-related trimer is loaded onto RPA-coated single stranded DNA and interacts with ATR kinase to med
    24 ed through pH-assisted thiol-gold bonding of single stranded DNA and salt aging, with preconjugated b
    25  telomeric G-quadruplex DNA to complementary single stranded DNA and to telomere binding protein POT1
    26 ys revealed that MtRecD binds efficiently to single-stranded DNA and linear duplexes containing 5' ov
    27 lyzed, radical reaction process that cleaves single-stranded DNA and requires only redox-inactive met
    28 nzymes, dimerization enables processivity on single-stranded DNA and results in higher levels of muta
    29 e selectivity of such a system in binding to single-stranded DNA and RNA is quadratically better than
    30 e and reveals new interactions between short single-stranded DNA and the vestibule of a biological po
    31 orts as to whether the enzyme also possesses single-stranded DNA and/or RNA 3'-5' exonuclease activit
    32 tional R-loops (RNA/DNA duplex and displaced single-stranded DNA) and DNA double-strand breaks (DSBs)
    33 H, which fills the Pol II active center with single-stranded DNA, and subsequent scanning downstream,
    34 bustly with specific sequences of unmodified single-stranded DNA, and we have identified five tags th
    35 binding of the human thrombin and its 15-mer single stranded DNA aptamer, under the application of ex
    36 , and high-affinity PET radioligand based on single-stranded DNA aptamer to address this challenge.  
  
    38 exed, expanded proteomic technique that uses single-stranded DNA aptamers to assay 4783 human protein
  
  
  
  
    43    Here the authors show that APOBEC3G binds single-stranded DNA as an active deaminase monomer, subs
  
  
  
    47 nthetic sequence that mimics freshly unwound single-stranded DNA at replication fork showed that RPA 
  
    49 when recombinantly expressed had the general single-stranded DNA binding activity of RPA complexes, u
  
  
    52 ralogous to the large subunit of the general single-stranded DNA binding heterotrimer replication pro
    53 ibria of cooperatively-bound clusters of the single-stranded DNA binding protein (gp32) of the T4 DNA
  
  
  
  
  
    59    The nascent DNA colocalized with the VACV single-stranded DNA binding protein I3 in multiple punct
    60 terize the role of filament formation by the single-stranded DNA binding protein ICP8 in the formatio
  
    62 lymerase gamma holoenzyme, the mitochondrial single-stranded DNA binding protein mtSSB, the replicati
    63 hairpin RNA (shRNA) screening, we identified single-stranded DNA binding protein replication protein 
    64 factor IIH prevented the accumulation of the single-stranded DNA binding protein replication protein 
  
  
  
  
  
  
  
    72 ethods, this amplification requires only the single-stranded DNA-binding protein gp32 from bacterioph
    73 A (RPA) is a highly conserved heterotrimeric single-stranded DNA-binding protein involved in DNA repl
    74 ressing cells also have higher levels of the single-stranded DNA-binding protein SSB1, which has a cr
  
    76 nal proteins, including the telomeric repeat single-stranded DNA-binding protein Teb1 and its heterot
  
  
  
    80 d of telomeric sequence-specific double- and single-stranded DNA-binding proteins, Taz1 and Pot1, res
  
    82 ication forks with topoisomerase I-generated single-stranded DNA breaks resulted in the generation of
    83 ive solvent environment that can concentrate single-stranded DNA but largely exclude double-stranded 
  
  
  
    87 pecificity of anti-lipid A antibodies toward single-stranded DNA combined with observed homology of S
  
    89 ion and emission shift of up to 120 nm for a single-stranded DNA construct, and (3) a sequence robust
    90 s, as well as numerous circular Rep-encoding single-stranded DNA (CRESS DNA) viral genomes, were iden
  
  
    93 -CRISPR), a targeting strategy in which long single-stranded DNA donors are injected with pre-assembl
    94 mbination of alternating double-stranded and single-stranded DNA (dsDNA and ssDNA) regions of varying
  
    96 f TER in the TERT-TER-p65 catalytic core and single-stranded DNA exit; extensive subunit interactions
    97 A double-strand breaks (DSBs) to generate 3'-single-stranded DNA facilitates DSB repair via error-fre
    98 applied directional deep sequencing of short single-stranded DNA fragments enriched for RNA-primed na
    99     The separation and partitioning of large single-stranded DNA fragments of the homologous chromoso
   100 on of the structure of S1-15 in complex with single-stranded DNA fragments, which may provide clues a
  
   102  We demonstrated that Brca2 protein prevents single-stranded DNA gap accumulation at replication fork
   103 tions arise through the aberrant repair of a single-stranded DNA gap, in a process that is dependent 
  
  
   106 phosphate, and also for cytosine residues in single-stranded DNA generated from a phagemid, in which 
  
  
   109  determine how they contribute to duplex and single-stranded DNA handling, and test the cellular cons
   110 ded binding proteins both protect and expose single-stranded DNA has important implications for our u
   111  an essential replisome component that binds single-stranded DNA, has a role in replication-coupled n
   112 yme that specifically modifies thymidines on single-stranded DNA in a sequence-specific manner by a n
   113 nduced DSBs are efficiently resected into 3' single-stranded DNA in cells and the major nuclease for 
  
  
  
   117 unequivocally establishes the existence of a single-stranded DNA incorporation pathway in human cells
  
   119 e adapters; subsequent PCR steps amplify the single-stranded DNA junction library in preparation for 
   120 gy presented by the upstream double-stranded/single-stranded DNA junction of the transcription bubble
  
   122 ude that ROS contribute to TLD by converting single-stranded DNA lesions into double-stranded DNA bre
   123   The aptamers were selected in vitro from a single-stranded DNA library of 1.8 x 10(15) oligonucleot
   124 NA hybridized to the complementary DNA and a single-stranded DNA loop, are formed in switch regions o
   125  cancer (PCa) that specifically binds to the single-stranded DNA molecule from a 277-nt fragment that
   126 enzymatically synthesize a micrometer-sized, single-stranded DNA molecule with only boranephosphonate
  
   128 pose that these contigs correspond to linear single-stranded DNA molecules that fold onto themselves 
   129 ate recombination (SPDIR), facilitates short single-stranded DNA molecules to invade and replace geno
   130 eads by measuring changes in ionic flow when single-stranded DNA molecules translocate through the po
   131 A1-RFA3) function as a complex that can bind single-stranded DNA molecules, promoting the repair of g
   132 mine the thermal motion of a voltage-clamped single-stranded DNA-NeutrAvidin complex in a Mycobacteri
   133 olecule arrays by electrostatically adhering single-stranded DNA of gene-like length onto positively 
  
   135 nal DNA origami, the DNR scaffold is a long, single-stranded DNA of tandem repeats, originating from 
   136 BAC simultaneously by co-transformation of a single-stranded DNA oligo and a double-stranded selectio
  
   138 ce receptor of interest is conjugated with a single-stranded DNA oligonucleotide, which hybridizes to
  
   140 n shown that MRN activity can generate short single-stranded DNA oligonucleotides (ssO) that may also
  
  
  
   144 ins for Proteomics) is an approach that uses single-stranded DNA oligonucleotides to capture specific
   145 and diffusion constants of several different single-stranded DNA oligonucleotides trapped in an MspA 
  
  
  
  
  
   151 sequence, the proteinosome payload (dextran, single-stranded DNA, platinum nanoparticles) is traffick
   152  and Rad52 to promote nucleation of Rad51 on single-stranded DNA pre-occupied by replication protein 
  
   154 which is able to detect the hybridization of single stranded DNA probe with its complementary target 
   155 fficient covalent immobilization of purified single-stranded DNA probe oligomers on cleaned gold micr
   156 orters we conjugated it to one terminus of a single-stranded DNA "probe" that was attached by its oth
  
   158 ate in methylated regions involving frequent single-stranded DNA processing as part of DSB repair.   
   159 ine starvation leads to accumulation of both single-stranded DNA regions and intracellular ROS, and i
   160  by facilitating the generation of RPA-bound single-stranded DNA regions upon replication stress in a
   161 ivery of CRISPR/Cpf1 ribonucleoproteins with single-stranded DNA repair templates results in precise 
   162 stranded MLPA products and subsequently to a single stranded DNA reporter probe bearing a HRP molecul
   163 nd resection, which generates long tracts of single-stranded DNA required for checkpoint activation a
  
  
   166 lection of high-affinity reagents based upon single-stranded DNA scaffolding of peptide fragments.   
  
  
   169 lity through the introduction of an unpaired single-stranded DNA spacer in the middle of each duplex.
   170 y of S1-15 and A6 and the reports of several single-stranded DNA-specific mAbs prompted the determina
   171 ions in the lattices using responsiveness of single-stranded DNA (ss-DNA), far less work has been don
   172 de experimental evidence that ComFA binds to single stranded DNA (ssDNA) and has ssDNA-dependent ATPa
  
   174 fication, hybridisation between short 25-mer single stranded DNA (ssDNA) fragments and a complementar
   175 ipment and facilitates the immobilization of single stranded DNA (ssDNA) probe sequences on a wide va
  
  
  
   179 ultiple target DNAs causes the corresponding single-stranded DNA (ssDNA) amplicons to be generated an
   180 ich forms helical nucleoprotein filaments on single-stranded DNA (ssDNA) and catalyzes strand invasio
   181 ate-free synthesis of high-molecular-weight, single-stranded DNA (ssDNA) and demonstrate that it proc
   182 anine (G), Cytosine (C), and Thymine (T)) on single-stranded DNA (ssDNA) and double-stranded DNA (dsD
   183 nnealase, a protein that binds complementary single-stranded DNA (ssDNA) and facilitates its annealin
   184 A orchestrates these processes by binding to single-stranded DNA (ssDNA) and interacting with several
  
  
   187 or surface of hexameric helicases to protect single-stranded DNA (ssDNA) and stabilize the complex in
   188 s a nucleoprotein filament that assembles on single-stranded DNA (ssDNA) at the sites of DNA damage. 
  
  
   191 his process is driven by the essential viral single-stranded DNA (ssDNA) binding protein ICP8, which 
  
   193 n protein A (RPA) is a ubiquitous eukaryotic single-stranded DNA (ssDNA) binding protein that serves 
   194 cation protein A (RPA), the major eukaryotic single-stranded DNA (ssDNA) binding protein, is essentia
  
   196  divergent bacteria can recognize and cleave single-stranded DNA (ssDNA) by an RNA-guided, PAM-indepe
   197 the stripping peak currents and logarithm of single-stranded DNA (ssDNA) concentrations in the range 
  
  
  
   201 DNA stretches, as in stem-loop structures of single-stranded DNA (ssDNA) derived from human immunodef
  
  
   204  through the cell cytoplasm, and deliver the single-stranded DNA (ssDNA) genome to the nucleus, where
   205  to track the population of unlabeled target single-stranded DNA (ssDNA) hybridized with probe DNA im
  
   207 search begins after RecA binds an initiating single-stranded DNA (ssDNA) in the primary DNA-binding s
  
  
  
  
  
   213 advances in paleogenomics, we have applied a single-stranded DNA (ssDNA) library preparation method t
  
   215 unwind double-stranded DNA (dsDNA) to reveal single-stranded DNA (ssDNA) needed for many biological p
   216 old nanoparticles (GNPs) self-assembled with single-stranded DNA (ssDNA) of nheA gene immobilized wit
   217 epsilon has greater contact with the nascent single-stranded DNA (ssDNA) of the leading strand on act
  
   219 nerated DSB ends are processed to yield long single-stranded DNA (ssDNA) overhangs, which are quickly
  
   221 RNA virus, and minute virus of mice (MVM), a single-stranded DNA (ssDNA) parvovirus, but not hepatiti
  
   223 her hand, BLM and RECQ5 demonstrated similar single-stranded DNA (ssDNA) reeling activities that were
   224 f an archaeal MCM N-terminal domain bound to single-stranded DNA (ssDNA) revealed ssDNA associating a
   225 totype hydrogel array which can analyze only single-stranded DNA (ssDNA) targets, the device is the f
   226 t and the stronger interaction of SWNTs with single-stranded DNA (ssDNA) than double-stranded DNA (ds
   227 te of cytosine deamination is much higher in single-stranded DNA (ssDNA) than in double-stranded DNA,
   228 egy relies on the preferential adsorption of single-stranded DNA (ssDNA) to GO over aptamer-target co
   229 d here shows how the C-terminal domains bind single-stranded DNA (ssDNA) to recognize the accumulatio
  
   231 tion and genomic substitution rates, RNA and single-stranded DNA (ssDNA) viruses may be important con
   232 gle-stranded DNA binding protein (SSB) wraps single-stranded DNA (ssDNA) with high affinity to protec
   233  (AFM) to show that Ver preferentially binds single-stranded DNA (ssDNA) with no sequence specificity
  
  
   236 ate containing RNA:DNA hybrids and displaced single-stranded DNA (ssDNA), has emerged as a major sour
   237 on of the DNA damage signal, accumulation of single-stranded DNA (ssDNA), sensitivity to replication 
   238  are factors that regulate the generation of single-stranded DNA (ssDNA), the enzymatic substrate of 
   239 rize the temperature-dependent elasticity of single-stranded DNA (ssDNA), where we find a significant
   240 monly used recombinant AAV vectors contain a single-stranded DNA (ssDNA), which is transcriptionally 
   241 or the detections of metal ion, dopamine and single-stranded DNA (ssDNA), with detection limits of 1.
   242 ing the ATR-dependent phosphorylation of the single-stranded DNA (ssDNA)-binding complex replication 
  
   244 sitive coactivator of transcription (PC4), a single-stranded DNA (ssDNA)-binding protein, as a novel 
  
  
  
  
  
  
  
  
   253 PF and ERCC-XPF and show that the binding to single-stranded DNA (ssDNA)/dsDNA junctions is dependent
   254 ch is able to detect hybridization of probe (single stranded DNA-ssDNA) and hybrid (double stranded D
  
   256 rogrammability of DNA base pairing to direct single-stranded DNAs (ssDNAs) to assemble into desired 3
   257  architectures of Watson-Crick complementary single-stranded DNA ("sticky end") linking strategies.  
   258 n alkaline solutions; whereas, the denatured single-stranded DNA strands readily reform duplexes at n
   259 ese mutants compared with wild type DnaC for single-stranded DNA, suggesting that the substitutions a
  
   261  is modulated by the nature of the 3'-ssDNA (single-stranded DNA) tail of the substrate and its effec
  
  
  
  
   266 r displays good discrimination between three single-stranded DNA targets studied: fully complementary
   267 gents, to prime second strand synthesis of a single-stranded DNA template and generate millions of pa
   268  is a robust assembly technique that folds a single-stranded DNA template into a target structure by 
  
   270 activation, overresection produces excessive single-stranded DNA that could lead to genomic instabili
   271 rial strategies (1) , especially small lytic single-stranded DNA (the microviruses) and RNA phages (t
   272 plification processing for the generation of single stranded DNA, thus presenting an assay that can f
   273 re we report the use of intrinsically chiral single-stranded DNA to achieve simultaneous handedness a
  
  
   276 D/APOBEC family enzymes convert cytosines in single-stranded DNA to uracils, causing base substitutio
  
  
   279 rminal ATPase of MCM is compact and contacts single-stranded DNA, via a set of pre-sensor 1 hairpins 
   280 In the case of the ubiquitous human circular single-stranded DNA virus family Anelloviridae, there is
  
  
  
  
   285 ore, the measurements of thermally denatured single-stranded DNA were carried out and the value of (G
  
  
   288 uble-strand breaks creates long stretches of single-stranded DNA, which are rapidly bound by replicat
   289 ecombination (HR) are first resected to form single-stranded DNA, which binds replication protein A (
   290 e-stranded breaks that are processed to form single-stranded DNA, which can invade a homologous chrom
   291 tides, called staple strands, to fold a long single-stranded DNA, which is called a scaffold strand, 
   292 sion of the DSB ends from double-stranded to single-stranded DNA, which is necessary to initiate DSB 
   293  an intrinsic preference for 5'-TC motifs in single-stranded DNA, which is the most frequently mutate
   294 t preparations lacking DNA were able to bind single-stranded DNA with high affinity (Kd approximately
   295 eir destinations allows for a simple robot a single-stranded DNA with one leg and two foot domains fo
   296  different nucleic acids shows that it binds single-stranded DNA with three-fold lower affinity than 
   297  reaction (PER) cascades, which grow nascent single-stranded DNA with user-specified sequences follow
   298 ocedure, subsets of hundreds or thousands of single-stranded DNAs with different lengths can selectiv
   299  for deaminating cytosine bases to uracil in single-stranded DNA, with characteristic sequence prefer
   300   Here, we present a study of surfactant and single-stranded DNA-wrapped SWNTs suspended in aqueous s
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