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1 amilies with only a single affected proband (singleton).
2 entifically described and many are rare (29% singletons).
3 00 variants at the targeted exons; >57% were singletons.
4 paralogs with identical exon structures and singletons.
5 om the reaction times to find other types of singletons.
6 of the reaction time in a visual search for singletons.
7 thods without the need for a large number of singletons.
8 sub-Saharan Africa is lagging behind that of singletons.
9 oided if ART twins and HOMs had been born as singletons.
10 the promoters of duplicates than at those of singletons.
11 ates--mainly small-scale duplicates--than in singletons.
12 r becomes similar to that of random pairs of singletons.
13 tinguishing hotspots from mono-modal H3K4me1 singletons.
14 22 exons of the KIF11 gene was performed on singletons.
15 horionic twins than in dichorionic twins and singletons.
16 lightly shorter in early adulthood than were singletons.
17 We also analyzed the subgroup restricted to singletons.
18 selection pressure to preserve such genes as singletons.
19 ant association when restricting analysis to singletons.
20 R STs (n = 109) were identified as unrelated singletons.
21 years, three times the mortality rate among singletons.
22 hemically classified into 57 clusters and 33 singletons.
23 lies, 97 were multiply affected, and 96 were singletons.
24 developing human infant sample including 58 singletons, 132 dizygotic twins, and 98 monozygotic twin
25 ton, 6941 twin, and 285 HOM infants, 1.0% of singletons, 15.4% of twins, and 34.7% of HOM children we
28 rs) of 151 healthy FT infants (50% male; 149 singletons, 2 multiples; mean [SD] birth weight, 3503 [4
29 6.4] years) of 149 VPT infants (49% male; 84 singletons, 65 multiples; mean [SD] birth weight, 1021 [
31 und within this collection; 26 isolates were singletons (a unique TLST sequence type [ST(T)]), some S
32 ce interval: 0.4, 0.7) shorter than were the singletons after adjustment for a series of background f
34 common Alu polymorphisms, but the density of singleton Alu insertions is constant across exonic and n
37 udy period was 3.6 per 10,000 live births in singletons and 5.1 per 10,000 live births in multiples.
38 semination (aOR, 1.00; 95% CI, 0.57-1.77 for singletons and aOR, 1.30; 95% CI, 0.76-2.21 for twins) o
39 ns) or ART (aOR, 1.38; 95% CI, 0.78-2.43 for singletons and aOR, 1.58; 95% CI, 0.94-2.65 for twins).
40 clustering at 97% similarity, and removal of singletons and chimeras, a total of 2741 (V4) and 2606 (
41 tion for this study includes 83,389 liveborn singletons and mothers enrolled in the Danish National B
44 iling any developmental domain but only when singletons and twins were evaluated together (aOR, 1.81;
46 erval: 1.15, 1.53) for twins or triplets vs. singletons) and lower gestational age (adjusted hazard r
47 heart defect is more common in twins than in singletons, and the increased occurrence is not restrict
49 higher rates of a vaginal birth of a healthy singleton at term within 24 months after randomization.
50 y outcome was the vaginal birth of a healthy singleton at term within 24 months after randomization.
51 ta occurred >3 times as often in twins as in singletons, at 3.9 (95% confidence interval, 2.6-5.8) an
52 ablished in Butajira, Ethiopia, and the 1006 singleton babies born were followed up at ages 1, 3, and
53 53 pregnant women who had a Medicaid-insured singleton birth between January 1 and December 31, 2010,
54 ental history of psychiatric disorders, twin/singleton birth, urbanicity, province of birth, and mate
57 healthy appropriately growing fetuses (e.g., singleton, birth weight appropriate for their gestationa
61 turned at 2 years for 891 (88%) of 1010 live singleton births (445 of (88%) 503 given NRT and 446 (88
63 es] and birth outcomes in a cohort of 64,705 singleton births (from 1999-2002) in Vancouver, British
65 tion-based cohort study was conducted on all singleton births at 22 or more completed gestational wee
68 Of 1536482 children born in Florida from singleton births from 1994 to 2002 with complete demogra
69 ections of US natality files with 16,198,654 singleton births from 28 states and Washington, DC, betw
70 lation-based case-control study of 1,510,064 singleton births from the Taiwanese birth registry durin
71 pulation-based retrospective cohort study of singleton births greater than 39 weeks gestation, in wom
77 ort study included all 2421284 children from singleton births in Sweden from January 1, 1973, to Dece
80 s a nationally representative sample of 5362 singleton births to married parents in England, Scotland
82 011), we included all primiparous women with singleton births who also had a sister with a first birt
84 records from 1998 to 2013 and found 1442590 singleton births with 37 to 41 weeks' gestation in the F
86 nrolled in the study, there were 224 preterm singleton births, of which 201 (90%) were enrolled in th
92 natal growth standards, we selected all live singletons born between 26 and before 37 weeks' gestatio
94 defect occurrence in all twins and 5% of all singletons born in Denmark in 1977-2001 and followed thr
95 lation-based birth cohort, consisting of all singletons born in Sweden in 1973-2003, was followed unt
96 a population-based cohort of 388,422 Danish singleton boys born alive (1997-2008), we studied the as
99 litus (GDM).The analysis included 918 mother-singleton child dyads from the Danish National Birth Coh
103 h Morbidity Record 02) databases for 801,592 singleton children attending Scottish schools in 2006-20
104 n this large, multiethnic clinical cohort of singleton children born at 28 to 44 weeks' gestation, ex
105 opment, a socially stratified sample of 5362 singleton children born in 1 week in March 1946 in Engla
106 longitudinal cohort study including 322 323 singleton children born in 1995-2009 at Kaiser Permanent
107 sed retrospective cohort study of women with singleton children born in Sweden from 1997 through 2011
108 -based cohort study comprising all live-born singleton children in Denmark from pregnancies overlappi
111 Survivors were assessed and compared with singleton control infants who were born at term and matc
112 population), 88 non-twins with autism and 84 singleton controls, we find high monozygotic twin-twin c
113 tness significantly more than deleting their singleton counterpart in S. pombe, revealing post-duplic
117 udy population included 74 178 women who had singleton deliveries between Feb 11, 1994, and June 2, 2
119 nter, population-based birth cohort study of singleton deliveries from 1996 to 2011 in Belgium, Franc
121 sing medical records of the first and second singleton deliveries in 25,820 Utah women (2002-2010).
122 ide, sulfur dioxide, and ozone among 223,375 singleton deliveries in the Air Quality and Reproductive
123 pective cohort (2002-2008), included 223,512 singleton deliveries of which 0.2% had hyperthyroidism,
128 traits (FWERacross), an increased burden of singleton disruptive variants in the Regulome was associ
129 urden that was prominent for large (> 1 Mb), singleton events (OR = 2.28, 95% CI [1.39-3.79], p = 1.2
130 including nearly every missense mutation as singleton events for the yeast transcription factor Gal4
134 ed a multicenter trial in which women with a singleton fetus who were attempting vaginal delivery at
135 age, 29.6 years) with an eligible sample, a singleton fetus without aneuploidy, results from cfDNA t
136 ed, randomised study, we included women with singleton fetuses at 26-32 weeks of gestation who had ve
137 ion-based data-linkage study of 321,287 term singleton first-born offspring born in Scotland, United
139 nd that these movements were directed to the singleton for both prosaccade and antisaccade trials.
140 February 2010 and December 2014, all with a singleton full-term birth (>/=37 weeks of gestation).
143 s of duplicate genes and deleting individual singleton genes from the yeast genome, leading to the co
144 e properties that distinguish duplicate from singleton genes, and the evolutionary impact of gene dup
147 ir relevant to LEC1, pseudogenization of the singleton GmLEC2 relevant to LEC2, and the rise of the L
148 iven medicinal chemistry optimization from a singleton hit against a cell-based pathway assay without
149 population-based cohort study including all singleton hospital births in Washington State, 2004-2013
155 of 856 children (85.1% of the 1006 original singletons in a population-based birth cohort) were foll
157 nd can lead to the same number of identified singletons in both Europeans and non-Europeans without a
158 national coverage about 75%), 610 live-born singletons in CKD, and 1418 low-risk controls recruited
160 of preeclampsia for women who delivered live singletons in Denmark in 1978-2008 (almost 1.4 million p
161 peans have significantly fewer nonsynonymous singletons in Online Mendelian Inheritance in Man (OMIM)
165 mappability as measured by the proportion of singletons increases steadily up to the length scale aro
166 We then measured the performance outcomes of singleton individuals of either phenotype at each task t
167 arous women aged 35 to 50 years delivering a singleton infant, 33.1% had labour induced: these women
172 of 422 appropriate for gestational age white singleton infants enrolled in the Fels Longitudinal Stud
173 of gestation in a random subcohort of term, singleton infants in the Collaborative Perinatal Project
175 European countries in 2011 and 2012 on 4594 singleton infants with gestational ages between 24 and 3
180 eaths, were documented for 888 of (88%) 1010 singleton infants; 445 (88%) of 503 infants in NRT group
182 uded 10,095 nonsmoking women who delivered a singleton live birth was carried out in Lanzhou, China,
184 es were used to select women who had vaginal singleton live births at least twice in Connecticut duri
187 included 845,345 offspring, representing all singleton live births in Finland between 1996 and 2010.
188 health region, and year of delivery) who had singleton live births in Quebec, Canada (1990-2007).
189 pulation-based cohort study consisted of all singleton live births in Sweden from January 1, 1982, th
190 verse birth outcomes, using natality data on singleton live births in the United States during 1990-2
191 Among 527 singleton stillbirths and 1,821 singleton live births studied, stillbirth was associated
193 hs, we selected 29,175 women who had vaginal singleton livebirths at least twice in Connecticut in 20
197 ree groups according to binding occupancy as singletons (low-occupancy), combinatorials (mid-occupanc
198 ch famine birth cohort consists of 2414 term singleton men and women who were born between 1943 and 1
199 motifs can lead to the multi-system disorder Singleton-Merten Syndrome (SMS) and increased interferon
204 IGRs using two independent the proportion of singleton mutations and the dI/dS ratio, where dI is the
205 ly in a twin cohort (n = 30) and age-matched singletons (n = 14) born at National Taiwan University C
206 score) damage in 1,671 twin pairs and 1,745 singletons (N = 5,087) drawn from three independent coho
207 h weight percentile was examined between the singleton neonates in the exposed group and a randomly c
208 d group and a randomly chosen subset of 1805 singleton newborns of the nonexposed group by performing
209 n became pregnant, 1962 women delivered live singleton newborns, and 1360 newborns were measured.
211 egisters, we constructed a cohort of 675,379 singletons, of which 15,014 children were born to asthma
213 ame includes 845345 pregnant women and their singleton offspring with data on maternal use of antidep
216 cades to the correct end point location: the singleton on prosaccade trials and the opposite distract
218 awa was characterised by a high frequency of singletons possibly due to constant additions from an ac
219 To test whether in asymptomatic women with singleton pregnancies and no prior spontaneous preterm b
221 ontaneous preterm birth who had asymptomatic singleton pregnancies and short transvaginal cervical le
222 rom three states, we constructed a cohort of singleton pregnancies at or beyond 20 weeks of gestation
223 mputer allocation (1:1) to assign women with singleton pregnancies between 22 weeks and 0 days' gesta
225 uid (AF) and cord blood (CB) samples from 36 singleton pregnancies complicated by preterm birth (PTB)
227 pulation-based linkage study of 979,912 term singleton pregnancies in Scotland, United Kingdom, betwe
229 estimated air pollution exposures for 6,074 singleton pregnancies in which GH was present and 199,98
230 preeclampsia in the short term in women with singleton pregnancies in whom preeclampsia was suspected
231 ngitudinal study of fetal growth in low-risk singleton pregnancies of women of high or middle socioec
237 from normal-weight women with uncomplicated, singleton pregnancies who delivered at the Magee-Womens
239 trial, we randomly assigned 1776 women with singleton pregnancies who were at high risk for preterm
240 we measured serum 25(OH)D in 5109 women with singleton pregnancies who were attending first-trimester
241 , we collected blood samples from women with singleton pregnancies who were undergoing standard aneup
242 imed to establish whether immediate birth in singleton pregnancies with ruptured membranes close to t
244 and women who were pregnant with singletons (singleton pregnancies) and who had a cervical length of
246 ional cohort study of nulliparous women with singleton pregnancies, from 8 clinical sites across the
247 rural Kenyan women aged 15 to 45 years with singleton pregnancies, gestational age of 13 to 23 weeks
253 ter, randomized trial involving women with a singleton pregnancy at 34 weeks 0 days to 36 weeks 5 day
254 ort study of nulliparous women with a viable singleton pregnancy at the time of the dating ultrasound
256 ive cohort study of nulliparous women with a singleton pregnancy in Cambridge, United Kingdom (2008-2
257 ized controlled trial, in which women with a singleton pregnancy were provided with DHA-rich fish-oil
258 ited States, we studied 2013 women who had a singleton pregnancy with a gestation of 24 weeks or more
259 articipants were older than 18 years, with a singleton pregnancy, gestation of less than 17 weeks, an
263 are identical to each other, saliency at the singleton's location can be measured by the shortness of
264 lad contaminated with Listeria monocytogenes singleton sequence type 382 (ST382), a serotype IVb-v1 c
265 l) in girls and women who were pregnant with singletons (singleton pregnancies) and who had a cervica
268 ed significantly from genes that reverted to singleton state in function, sequence composition, expre
270 ultimately appear to be largely restored to singleton status, suggesting that these genes may be dos
272 mpound-heterozygous RNASEH1 mutations in two singleton subjects and a homozygous mutation in four sib
274 AA exposures and birth weight of up to 7,438 singleton term babies using multiple linear regression,
275 the Medical Birth Register included all live singleton term births in Sweden between 1992 and 2010.
276 ected consecutively if they had at least one singleton term delivery with head presentation and if th
277 y population was restricted to nonanomalous, singleton, term pregnancies with no prepregnancy hyperte
282 an antenatal clinic in Northern Ireland with singleton uncomplicated pregnancies and reported taking
283 n in the duplicates' expression than that of singletons under a range of stress conditions, sparking
284 distribution of the reaction times to find a singleton unique in color, orientation, and motion direc
285 y ranged from 1.3 to 6.6 d: 0.5 to 6.2 d for singleton vaginal deliveries and 2.5 to 9.3 d for cesare
286 mulated genes we identify two siblings and a singleton variably demonstrating severe neonatal anemia,
287 owed a significant association with damaging singleton variants in a Cav2-adaptor gene set (odds rati
292 cluding sex, age at diagnosis, birth weight, singleton versus multiple birth, parity, parental age, t
294 ister, whereas the corresponding numbers for singletons were 648 of 74 473 (0.87%; P<0.001; ie, a 63%
299 rom 3 independent cohorts: brother pairs and singletons with and without a history of inhibitors, as
300 thout major complications and delivered live singletons without congenital malformations (the analysi
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