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1 colonies performed poorly at the flower poor site).
2 l peptides and residues of the ACE catalytic site.
3 independently regulated, co-agonist-binding site.
4 ting the neutralizing epitope (NE) antigenic site.
5 espect to the substrate in the enzyme active site.
6 blocks of 3 and 6), and stratified by study site.
7 proximately 100-300 mum away from the injury site.
8 a pyridine-like nitrogen across the vacancy site.
9 ly to beta-tubulin at the colchicine binding site.
10 s reduced after mutation of the Sp-1-binding site.
11 as progesterone, likely binding to the same site.
12 the number of intergenic SNPs per intergenic site.
13 ther sites, and below a factor of 1.3 at one site.
14 fectively disassemble the adenylation active site.
15 oglycan-synthesizing enzymes to the division site.
16 ajor autolysin LytA and occurs at the septal site.
17 -ring for recruitment to the future division site.
18 of the COX2 C-tail that contains the apo-CuA site.
19 4 per 100000 in NETs with an unknown primary site.
20 or are immediately upstream of the cleavage site.
21 on's disease but not in controls at a single site.
22 lysis revealed four resolved factors at each site.
23 gatively affected by herbivores in subarctic sites.
24 or under-represented among different cancer sites.
25 enation and moderate to strong Bronsted acid sites.
26 are adapted to colonize different metastatic sites.
27 , 11.2% in the oral cavity, and 8.8% at both sites.
28 e able to identify six T-bet phosphorylation sites.
29 opic bone formation above the mesh in 72% of sites.
30 nts in pockets of enzymes stabilizing active sites.
31 he stabilizing effect at many of the mutated sites.
32 conversion of amines to quaternary ammonium sites.
33 r targeting amplicons with conserved priming sites.
34 maximize CO2 uptake within and above storage sites.
35 ott scenario without real charge order on Ni sites.
36 , AU-rich sequences, and Pumilio recognition sites.
37 ing a mutation(s) at the transmitter-binding sites.
38 eractions and identify their genomic binding sites.
39 ent of the strength and number of competitor sites.
40 can bind pre-acetylated nucleosome-depleted sites.
41 o GAS pathogenesis at multiple host anatomic sites.
42 d more likely to contain nonconsensus splice sites.
43 alter metal uptake by blocking key reactive sites.
44 tchener), including three upstream reference sites.
46 were created in healed maxillary extraction sites 1) by drilling or 2) by drilling followed by stepw
51 d the functional importance of S-nitrosation sites across the mammalian proteome, remain largely unch
52 of 39 kb that contains DNAse hypersensitive sites active at a restricted time window during retinal
53 t evident upon re-inspection of one of these sites after 18 months, indicating how evidence of distur
54 he impact was more marked at the flower-rich site (all colonies performed poorly at the flower poor s
55 y AXO from unplanned explosions at munitions sites, although the grey literature suggests that AXO is
57 Transcriptome and genome-wide GABP-binding site analyses identify GABP direct targets encoding prot
58 (NMDAR) is controlled by a glutamate-binding site and a distinct, independently regulated, co-agonist
60 nese and cobalt can bind to the same nonheme site and confer HCO activity in a heme-nonheme biosynthe
62 potential existence of an additional binding site and provide new insights into GB1:IgG complex struc
64 eless, the evolution of the receptor-binding site and the stem region on HA is severely constrained b
65 ation under O2 to open a cobalt coordination site and to oxidize Co(II) to Co(III), as evidenced by o
67 eting of Fli1 to favour nearby Sox consensus sites and enhances the vascular function of converted ce
69 reduced editing at 38 mitochondrial editing sites and increased editing at 24 sites; therefore the a
70 predict the CO binding at a large number of sites and select four exhibiting CO binding stronger tha
71 NFkappaB dimers bind to a myriad of genomic sites and switch the targeted genes on or off with preci
72 s in the methyl esterification of all acidic sites and the conversion of amines to quaternary ammoniu
74 acid protein containing five F-actin-binding sites and two G-actin-binding sites, and interacts with
75 markably, the glycan patterns, glycosylation site, and their occupancy by N-glycans are all detected
76 g, 3.56 per 100000 in gastroenteropancreatic sites, and 0.84 per 100000 in NETs with an unknown prima
78 -actin-binding sites and two G-actin-binding sites, and interacts with wheat (Triticum aestivum) Acti
79 distinct kinetic profiles, even for proximal sites, and this suggests that target sequence and chroma
80 region abolishing the N-linked glycosylation site; and 2 variants represented the head domain, 1 comp
81 Nase-seq, DNase hypersensitive site mapping, site annotation and motif identification for DNase-seq,
85 a shared core protein fold but whose active sites are located in entirely different regions, illustr
86 uired for efficient Ede1 localization at CME sites are the third EH domain, the proline-rich region,
87 ccurs through an unusual ground state active site arrangement or by thermally sampling conformational
90 tein adducts requires ATP hydrolysis at both sites, as does the stimulation of ATM kinase activity.
91 We further identify a naturally polymorphic site at Nef position 9 that contributes to the MHC-B dow
93 e transmembrane helices and effector docking sites at the intracellular surface of the beta1AR, but t
94 heostoma caeruleum) were collected from nine sites at varying distances from two major municipal wast
95 h/branch-site models and unrestricted branch-site-based models (BS-REL, BUSTED and RELAX)), our resul
96 ide of a membrane system and seal the defect site because of increased hydraulic drag through damage
97 r to T1 closure such that the U5-A6 cleavage site becomes embraced to achieve its cleavage competent
98 are naturally curved at each of the cellular sites believed to engage in autophagosome formation, rev
99 biased low by more than a factor of 2 at six sites, between a factor of 1.5 and 1.8 at six other site
101 1 in APP from the Glu(11) site to the Asp(1) site both in male and female transgenic mice in vivo and
103 nzyme, CNbeta1, is autoinhibited at a single site by either of two inhibitory regions, CBD and LAVP,
104 on and the core H-bond network in the active site by relocating to replace the missing Arg85' sidecha
106 the hetero-tetramer interface and the active sites can abolish Pseudomonas aeruginosa growth in a def
108 nd identifies surface features, H(+) binding sites, Ce(3+) locations, and O vacancies on (100) facets
110 ly Treatment Program (RAISE-ETP) study, a 34-site cluster-randomized trial, compared NAVIGATE, a coor
111 ompared to controls across single- and multi-site cohorts, and increased over 1 year in Parkinson's d
113 Free-energy simulations elucidate the active site conformations in the AppA (activation of photopigme
114 We also mapped phage 9 g DNA packaging (pac) site containing two 21-bp direct repeats and a major ter
116 FR tyrosine phosphorylation, particularly of sites corresponding to the binding specificity of the ov
117 op is relocated by pressure was validated by site-directed mutagenesis and by inhibition by small pep
118 sible spectroscopy, heme quantification, and site-directed mutagenesis of histidine residues, we demo
120 t and its implications for heme transfer via site-directed mutagenesis, resonance Raman (RR), hydroge
122 The discovery of Neandertals at open-air sites during the late MP reinforces the view that Neande
127 nd divisive, to split groups when functional site features suggest distinct functionally-relevant clu
128 add sequences containing similar functional site features, and divisive, to split groups when functi
129 all NMR parameters: Starting as a nucleation site for monomer-monomer contacts, this six-residue sequ
130 on to the Orai C terminus, the main coupling site for STIM1, the Orai N terminus is indispensable for
132 a conserved kinase, DDK, provides a binding site for the Scc2/4 cohesin loading complex, thereby dir
133 was predicted to disrupt a consensus binding site for the transcription factor ETS within an enhancer
136 on, we identified transcriptome-wide binding sites for RNA polymerase II and the exosome cofactors Mt
137 ifs enriched in the PREs are cognate binding sites for the identified transcription factors and are n
140 s and support the use of tonsils as lymphoid sites for the study of germinal center reactions after v
141 predominantly in liver and small intestine, sites for triglyceride-rich lipoprotein biogenesis and e
142 ciated lymph nodes (LNs), and other lymphoid sites from 78 individuals ranging from less than 1 year
143 fy canonical and non-canonical miRNA-binding sites from peaks identified by Ago2 Cross-Linked ImmunoP
145 e based on DNA methylation at 329 unique CpG sites, has a median absolute error of 3.33 weeks and has
146 proteins from the scPDB database of binding sites have been evaluated using both a distance and a vo
147 nism of cyclization within the enzyme active site; however, there is evidence that conformational res
149 ensed antibody palivizumab, which recognizes site II on both the pre-F and post-F proteins, is restri
150 izing a compound known to block the H3K27me3 site in EED discovered by in-house screening, Novartis s
152 the complete glycosylation profile at every site in multiple HIV-1 Env trimers, accomplishing two go
155 econd (-)3TC-TP molecule bound to the active site in the absence of PPi, suggests that nucleotide bin
156 analysis indicated Lys-72 as an acetylation site in the ERK1 N terminus, adjacent to Lys-71, which b
159 s consistent with coalescence of the 5 and 3 sites in a complex (I, initial), but if this cannot form
160 ar factor kappa B (NFkappaB) from DNA target sites in a process we have termed molecular stripping.
163 location frequency to IGH and AID off-target sites in human chronic lymphocytic leukaemia and mantle
164 (MAbs) that recognize known major antigenic sites in MeV-H, we identified a D4 genotype variant that
167 to identify pathways and their postsynaptic sites in the amygdala in rhesus monkeys, we found that t
168 y, we found that methylation at multiple CpG sites in the HOXA4 promoter region was associated with h
170 of enriched transcription factor DNA-binding sites in the promoters of differentially expressed genes
172 species between peri-implant and periodontal sites in the same individuals, suggesting similar pathog
173 studies of the beta1AR define ligand-binding sites in the transmembrane helices and effector docking
178 ther nutrient starvation or use of an active site inhibitor reduces Skp2 levels and stabilizes LT, le
180 l adenosine generated by cells at the injury site is critical for protection from IRI through bone ma
181 Results demonstrated that a miR398 binding site is eliminated in AhCSD1-2.2 as a consequence of alt
182 ylation of STAT5B on the JAK2-dependent Y699 site is significantly reduced in the liver and skeletal
183 n immediately downstream of the S2' cleavage site is the FP (amino acids 798-818 SFIEDLLFNKVTLADAGFMK
186 from multiple interdependent phosphorylation sites is required for a GC-A conformation capable of tra
187 revealed subspecies clades specific to body sites; it also quantified species with phylogenetic dive
189 PtdInsPs interact with the polyanion-binding site located on an inner chamber wall of the enzyme.
190 wly created islands and five nearby mainland sites located in the Brazilian Cerrado, a biodiversity h
191 rthritis (RA) infiltrate non-lymphoid tissue sites, maneuver through extracellular matrix and form la
192 itioning for MNase-seq, DNase hypersensitive site mapping, site annotation and motif identification f
193 athrin-mediated endocytosis (CME), endocytic-site maturation can be divided into two stages correspon
194 mulation, acupuncture at local versus distal sites may improve median nerve function at the wrist by
196 iety of approaches (restricted branch/branch-site models and unrestricted branch-site-based models (B
197 sion was affected by CNOT3 loss, and also at sites modulated in certain types of colorectal cancers.
199 ly, analysis of transcription factor-binding site motifs of differentially dysregulated genes uncover
200 te recessive allele is due to a splice donor site mutation in the scavenger receptor B1 (SCARB1; also
202 on energy is weak because only a few binding sites near the collision point contribute significantly
203 efractory disease, mediastinal primary tumor site, nonseminoma histology, intermediate- or poor-risk
204 f chronic pain can also induce a generalized site-nonspecific enhancement in the aversive response to
206 minus of chECL1, suggesting that the binding site of ALV-J gp85 on chNHE1 is probably located on the
207 tion, shifted the preferential beta-cleavage site of BACE1 in APP from the Glu(11) site to the Asp(1)
209 cells and their progenitors are an important site of HCMV latency, and one viral gene expressed by la
210 olonization of the lower airways, the actual site of inflammation in asthma, which is hardly accessib
211 of EGP during a clamp, reaffirming that the site of insulin action to control EGP is extrahepatic.
218 ssibly other microorganisms and form EETs at sites of airway epithelial damage to protect the host fr
219 e as important as platelets to thrombosis at sites of arterial injury and that platelets contribute t
222 ground in many important tissues that may be sites of infection such as the lungs and soft tissues.
223 d the function of APC and TC accumulating at sites of inflammation after segmental allergen challenge
225 alf the identified proteins possess multiple sites of phosphorylation that are often clustered, where
226 -mediated endonucleolytic cleavage of DNA at sites of protein adducts requires ATP hydrolysis at both
231 ive in liver cells, enriched for the binding sites of the FOXA1, FOXA2 and HNF4A transcription factor
233 ally identifying the ampullae as the primary sites of viral persistence, combined with the fact that
234 DNA backbone specifically near the mismatch site on a 27-mer fragment, consistent with mismatch targ
236 activity, and colocated with AR at specific sites on chromatin to regulate genes relevant to disease
237 ect of fuel loads (fat) acquired at stopover sites on the subsequent pace of migration has not been q
239 H2 is unable to process an abasic rNMP (rAP site) or a ribose 8oxoG (r8oxoG) site embedded in DNA.
241 equencing analysis reveals that LSD1 binding sites overlap significantly with those bound by the S-ph
243 ng Ska complex, which enriches at attachment sites prior to anaphase onset to dampen chromosome motio
244 erTAD have a high enrichment of CTCF binding sites, promoter-related marks, and enhancer-related hist
245 and the higher number of hydrogen bond donor sites provides a remarkable enhancement of its binding e
249 e lack of an appropriately positioned active site residue as a catalytic base leads us to propose an
250 manuscript, we have focused on OleTJE active site residues Phe(79), His(85), and Arg(245) to interrog
252 complex hydrogen bond network of four active site residues, which was installed in the late stages of
253 and -230 mV, respectively, in the Q-binding site, respectively, suggesting that release of the Q tow
254 d constitutively phosphorylates a downstream site (S719) that accounts for 40% of basal NHE3 activity
256 ic X-ray response can be explained with the "site-selective" Mott scenario without real charge order
261 ely small samples in the dyadic analysis and site-specific analysis call for caution in interpreting
271 bility of neurotrophic factors in the lesion site, thereby promoting axonal regeneration and locomoto
272 al editing sites and increased editing at 24 sites; therefore the absence of MEF8 affects 11% of the
274 e alternating tropomyosin- and actin-binding sites (TMBS1, ABS1, TMBS2, ABS2), Lmods lack TMBS2 and h
275 eavage site of BACE1 in APP from the Glu(11) site to the Asp(1) site both in male and female transgen
276 f the study include the exclusivity of study sites to India, lack of prior HIV/HCV diagnosis confirma
278 inding, CTCF quickly rebinds another cognate site unlike cohesin for which the search process is long
281 r prediction of transcription factor binding sites using an integrative energy function that combines
282 SNPs associated with DNase I-hypersensitive sites was also found in many tissue types, including bra
287 In 15 non-Hodgkin lymphomas, many more sst2 sites were labeled with the antagonist than with the ago
288 L3 regions, which flank the di-Zn(II) active site, were selectively (19) F-labeled using 3-bromo-1,1,
289 f the cofactor transiently enters the active site where it displaces the pterin ring of the THF produ
293 in the more recently designated Natura 2000 sites, which are subject to high human accessibility.
294 ce differences were revealed among the three sites, while specificity and NPV of MALDI-TOF MS for mal
296 l electrograms had corresponding endocardial sites with BV <1.50 mV, and the remaining could be ident
297 rmed by neighboring tetrahedral interstitial sites, with analytical solutions for basin exiting time
299 The apparent diffusion coefficients of these sites within PEC films of poly(diallyldimethylammonium),
300 e protein scaffold that surrounds the active site, yet the exact nature of catalytically relevant pro
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