ライフサイエンスコーパス: skeleton

1 e, suggesting a crucial role for SHP2 in the skeleton.

2 t forged the azetidine ring on the okaramine skeleton.

3 the most vascularized regions of the growing skeleton.

4 jection of human cancer cells into the mouse skeleton.

5 ally difficult or impossible to apply to the skeleton.

6 us) with a closely associated small theropod skeleton.

7 on with 4-bromobutanal to give the tricyclic skeleton.

8 able for diagnosing chronic infection of the skeleton.

9 ity of the endo-2-substituted-5,6-norbornene skeleton.

10 ole alkaloids that have a complex polycyclic skeleton.

11 in a ciliopathy with primary effects on the skeleton.

12 edented tetracylic anvilane terpenoid carbon skeleton.

13 els must decline substantially to impact the skeleton.

14 a), remain regionally expressed in the adult skeleton.

15 acts with ankyrin complex at the erythrocyte skeleton.

16 5-17] are expressed throughout Eunotosaurus' skeleton.

17 anges at key points of our lead compound SG2 skeleton.

18 ntagonists based on the 1,3-dioxoisoindoline skeleton.

19 ere is a remarkable recovery of the maternal skeleton.

20 ocalize with And1, a component of the dermal skeleton.

21 nd the specific anatomic location within the skeleton.

22 high bone mass in the appendicular and axial skeleton.

23 ubstitution on the C7 of the pyrrolocytosine skeleton.

24 ble ectopic bone in their hyoid craniofacial skeleton.

25 ve synthesis of diterpenes with the halimane skeleton.

26 mensionally ordered macroporous (3DOM) Mn2O3 skeleton.

27 cesses underlying the development of the fin skeleton.

28 deformed bones in one or more regions of the skeleton.

29 (DNP), lowers the symmetry of the porphyrin skeleton.

30 ps) assembly of a functionalized cardenolide skeleton.

31 ical defects to the pouches and craniofacial skeleton.

32 e throughout the ancestral vertebrate dermal skeleton.

33 res, DPT shows a curved pi-conjugated carbon skeleton.

34 homeostasis are unclear in the healthy adult skeleton.

35 translocates to the unique cortical membrane skeleton.

36 alpha-chiral centers from this abundant C-4 skeleton.

37 ting appropriate tissue architecture of limb skeleton.

38 magnetic resonance (MR) imaging of the axial skeleton.

39 , which the organisms incorporate into their skeleton.

40 ased on humulane, amorphene, and himachalane skeletons.

41 bout how stony corals build their calcareous skeletons.

42 the efficient synthesis of spiro-indandione skeletons.

43 dular inputs and divergence of two different skeletons.

44 ntact, but this is seldom achievable for all skeletons.

45 anage this without the use of hard, internal skeletons.

46 talyzed synthesis of cyclopenta[b]benzofuran skeletons.

47 e generated, which we cluster into 74 cyclic skeletons.

48 es of interest are based primarily on carbon skeletons.

49 rphology and, potentially, function of coral skeletons.

50 aromatic carbazole (i.e., [2,3]-benzoindole) skeletons.

51 ymer composite equipped with 3D interlocking skeleton (3D IL) is developed through a simple freeze-ca

52 [7] and remain occluded and preserved in the skeleton [8-10].

53 The most common sites involved were the skeleton (90.6% of patients, including 47% with axial an

54 This concept requires only a compressible skeleton, a flexible skin, and a fluid medium.

55 asily accessible 2-bromo-3-aminopyridizinone skeleton, a tandem Sonogashira coupling-cycloisomerizati

56 may lead to abnormal growth of the orofacial skeleton, affecting the overall structure of the face.

57 and rapid entry to bridged tricyclic tropane skeletons, allowing for five contiguous carbon stereocen

58 ox9-13) are critical for patterning the limb skeleton along the proximodistal axis during embryonic d

59 tion of the prenyl group within the phenolic skeleton also influenced the antibacterial activity.

60 re used to compare FA along the white matter skeleton among the three subject groups.

61 n that facilitates communication between the skeleton and adipose tissue.

62 failure load and stiffness of the peripheral skeleton and dietary protein intake, which is mainly rel

63 ied from histological sections using Image J skeleton and fractal analysis procedures at three time p

64 ing eye, heart, ear, craniofacial nerves and skeleton and genital organs.

65 is the most common primary malignancy of the skeleton and is prevalent in children and adolescents.

66 d tetrazines showed negligible uptake in the skeleton and joints when administered in the absence of

67 ecies with electron deficiency in the carbon skeleton and negative charge at the oxygen end that upon

68 xpression in specific structures in the eye, skeleton and other organs, where it may regulate the fib

69 dy population, (18)F-FLT uptake in the axial skeleton and proximal limbs assessed by SUVmax correlate

70 l, which cause mineralization defects in the skeleton and teeth (osteomalacia/odontomalacia).

71 n the level of coupling between the membrane skeleton and the plasma membrane.

72 ticles (around 200 nm) mainly located in the skeleton and toward the outer surface of the sponge.

73 s a programmed cell fate change in postnatal skeleton and unravels a regulatory mechanism underlying

74 Amines with a wide scope of skeletons and functional groups are tolerated.

75 al composition, including different types of skeletons and substitutions, and antibacterial propertie

76 r or proximal humerus vs other limb vs axial skeleton); and presence of metastases (no vs yes or poss

77 s-Alder reaction to generate the cis-decalin skeleton, and a late-stage large fragment union exploiti

78 complex systems biology between the kidney, skeleton, and cardiovascular system in native and transp

79 ing involving the C12OH group of the steroid skeleton, and the acidic function of some bile salts, mi

80 uid is under-saturated with respect to their skeleton, and the skeleton of their primary spines is in

81 ether other structural forms of the membrane skeleton are present in neurons.

82 Five of the 74 skeletons are found in known natural products; some of t

83 growth of coral colonies and contraction of skeletons, are extremely limited.

84 n of peripheral neurons and the craniofacial skeleton as previously reported.

85 mutants showing changes in the shape of the skeleton as well as defects in pigmentation.

86 P for the tailoring of the cucurbitacin core skeleton as well as two other CYPs responsible for the k

87 ern, however, reflects organisms with robust skeletons, as only one exceptionally preserved Hirnantia

88 f varying length and attached to the steroid skeleton at C3, the difference in potency between tonic

89 Our model also includes detail of the skeleton attachment to the fluidlike lipid bilayer membr

90 features that include global, contour-based, skeleton-based, and PC-specific object descriptors.

91 and compared across the entire white matter skeleton between groups, and correlated with cognitive m

92 mong the most common cell types in the adult skeleton; both mature adipocytes and preadipocytes serve

93 bserve a decline in the (15)N/(14)N of coral skeleton-bound organic matter, which signals increased d

94 the bonding interactions in the Sc-OCPPCO-Sc skeleton but also to compare to the linear mode observed

95 two chiral spiro compounds with very similar skeletons but showing almost mirror-image electronic cir

96 Bone marrow stromal cells maintain the adult skeleton by forming osteoblasts throughout life that reg

97 Clec11a thus maintains the adult skeleton by promoting the differentiation of mesenchymal

98 Terpenoid synthases create diverse carbon skeletons by catalyzing complex carbocation rearrangemen

99 Do corals form their skeletons by precipitation from solution or by attachmen

100 The study of genetic disorders of the skeleton can yield insights that fuel experimental thera

101 ies of the endo-2-substituted-5,6-norbornene skeleton, can be prepared using Mo(N-2,6-Me2C6H3)(CHCMe2

102 is a plasma cell cancer that develops in the skeleton causing profound bone destruction and fractures

103 notype in the appendicular but not the axial skeleton compared to the littermate controls.

104 5), from the Hamann-Todd collection of human skeletons compiled from 1912 to 1938, and 15 individuals

105 We describe a highly organized knob skeleton composed of a spiral structure coated by an ele

106 ve different morphologies, but have the same skeleton composed of F-actin.

107 e extravascularly and form a unique membrane skeleton, composed of spectrin, 4.1R-complex, and ankyri

108 sils, suggesting that this taxon possessed a skeleton comprised of spicules.

109 The vertebrate axial skeleton comprises regions of specialized vertebrae, whi

110 rks and skates) possess a postcranial dermal skeleton consisting of tooth-like "denticles" embedded w

111 d tail forms a blastema, and the regenerated skeleton consists of a cartilage tube (CT) surrounding t

112 Its tetracyclic skeleton contains three quaternary carbons and is marked

113 , such as peripheral substituents, molecular skeleton, coordinated metal, allows creating a vast libr

114 The volume and surface area of dead skeletons decreased by 52% and 47%, respectively, corres

115 semi-automated method was used to calculate skeleton density (SD), vessel density (VD), fractal dime

116 ng of the Australopithecus afarensis partial skeleton DIK-1-1, from Dikika, Ethiopia, provides the on

117 the oldest and most complete fossil hominin skeletons discovered.

118 , reports on chiral beta-ketoester molecular skeletons display a steady increase.

119 egion, peaking at (d=0.42) for the entire WM skeleton, driven more by peripheral areas as opposed to

120 ad to a permanent disruption of the membrane skeleton due to the inability of spectrin filaments to s

121 ques exerted on, and motion of the syringeal skeleton during song.

122 multiple organs, including the craniofacial skeleton, ear, branchial arches, heart, lungs, diaphragm

123 We report on a juvenile partial skeleton (El Sidron J1) preserving cranio-dental and pos

124 one of the most complete Cretaceous sauropod skeletons ever found in Australia, whereas a new specime

125 sopressin (Avp) have opposing actions on the skeleton exerted through high-affinity G protein-coupled

126 The morphology of the vertebrate skeleton exhibits tremendous plasticity in evolution, al

127 The developing skeleton experiences mechanical loading resulting from e

128 ually intact, comprising a fully articulated skeleton exposed in dorsal view.

129 encapsulating iodine while the porous carbon skeleton facilitates redox reactions of iodine and ion i

130 Prx1-Cre;KL(fl/fl) mice but not their axial skeleton failed to increase FGF23 expression as observed

131 kaloid noteworthy for its unique pentacyclic skeleton featuring a 3-azabicyclo[3.1.0]hexane substruct

132 ering of biological actuators and 3D-printed skeletons for any design application.

133 re increased for providing energy and carbon skeletons for cellular metabolism.

134 osynthetically derived sugar provides carbon skeletons for lipid biosynthesis.

135 rch for the asymmetric construction of these skeletons for which enantioselective syntheses are still

136 nside reduced graphene oxide (rGO) nanosheet skeletons, for high-performance flexible SCs.

137 cles are formed inside tissue may make coral skeleton formation less susceptible to ocean acidificati

138 b) a one-pot construction of the tetracyclic skeleton from an omega-isocyano-gamma-oxo-aldehyde via a

139 complete mitochondrial genomes of 52 ancient skeletons from present-day Armenia and Artsakh spanning

140 ratios of strontium for 84 radiocarbon-dated skeletons from seven archaeological sites of the Late Ne

141 ive erythroblasts express the major membrane skeleton genes present in similarly staged definitive er

142 Over the past decade, the hexaphyrin skeleton has emerged as a multifaceted frame exhibiting

143 Several partial skeletons have revealed that the thoracolumbar transitio

144 involved in construction of the basic carbon skeleton, have been identified in insects to date.

145 s act on bone or where these WNTs act in the skeleton; however, loss-of-function mutations in WNT1 ca

146 Because flexibility of the molecular skeleton impaired full characterization of relative ster

147 SMOC2 disruption affects the facial skeleton in a dose-dependent manner.

148 of the ceratohyal angle of the craniofacial skeleton in bptf F0 mutants, indicating abnormal craniof

149 in ecdysozoan invertebrates and the internal skeleton in Deuterostomia, including vertebrates.

150 highly functionalized sesquiterpene lactone skeleton in five steps via an enantioselective ketone al

151 current clinical practice for staging of the skeleton in patients at risk of bone metastases.

152 he formation and composition of the membrane skeleton in primitive erythroblasts, which progressively

153 iloring enzymes that modify the aminoquinone skeleton in the biosynthesis pathway of Streptomyces spe

154 ral crest can contribute to the craniofacial skeleton in vivo.

155 ton is the model for spectrin-based membrane skeletons in all cells, and because defects in the red c

156 Using craniometric evidence from the skeletons in conjunction with archaeological data, we di

157 Multiple oxazole skeletons in the aryl periphery are constructed in a sin

158 ramines B (1) and D (2) contain a polycyclic skeleton, including an azocine ring and an unprecedented

159 Patterning of the facial skeleton involves the precise deployment of thousands of

160 The red cell membrane skeleton is a pseudohexagonal meshwork of spectrin, acti

161 A five-membered ring indene skeleton is also prepared via olefin isomerization, 1,2-

162 g a new type PARP inhibitor with distinctive skeleton is alternatively promising strategy for TNBC th

163 id-specific, protein 4.1R-dependent membrane skeleton is an important feature not only of definitive,

164 This knob skeleton is connected by multiple links to the erythrocy

165 The craniofacial skeleton is derived from both neural crest cells and mes

166 The molecular skeleton is formed using the first examples of two criti

167 nsitive to ocean acidification (OA) as their skeleton is made of high-magnesium calcite, one of the m

168 Although the skeleton is one of the predominant sites for breast canc

169 The calcium carbonate skeleton is secreted by primary mesenchyme cells (PMCs)

170 ke the soma and dendrites, the axon membrane skeleton is structured as a series of actin rings connec

171 At 3.3 million years ago, the DIK-1-1 skeleton is the earliest example of this distinctive and

172 e is important because the red cell membrane skeleton is the model for spectrin-based membrane skelet

173 nt of biological sex to archaeological human skeletons is a fundamental requirement for the reconstru

174 The metal ion in the center of the DPP skeletons is strongly coordinated with the nitrogens of

175 d access to unprecedented diverse fused THIQ skeletons, is metal/catalyst free, has a cleaner reactio

176 s demonstrate the importance of IFT81 in the skeleton, its role in the anterograde transport complex,

177 cord itself: compression fossils surrounding skeletons lack the finest morphological details and seld

178 tetracoordinated boron atoms with semiplanar skeleton ligands.

179 tes are responsible for the formation of the skeleton long bones.

180 In arthritis of the axial skeleton, mainly spondyloarthropathies, whole-body MR im

181 The spectrin-based membrane skeleton maintains the biconcave shape of erythrocytes,

182 Skeleton mean diffusivity showed the closest correlation

183 (euechinoids), but the impact of etching on skeleton mechanical properties is almost unknown.

184 chor density and thereby the strength of the skeleton/membrane attachment.

185 We define a negative pressure between the skeleton/membrane connection that promotes separation; c

186 th cranial and postcranial elements from two skeletons, Mierasaurus bobyoungi gen.

187 ology allows for quantification of syringeal skeleton motion and forces, acoustic effects of muscle r

188 the alpha-benzo positions of the macrocycle skeleton, MPc(OBu)8, have strong near-infrared absorptio

189 olecules form a membrane-associated periodic skeleton (MPS) in neurons.

190 tanding of this membrane-associated periodic skeleton (MPS), it is important to address how prevalent

191 nset, severe developmental defects involving skeleton muscle, brain and eye, such as the muscle-eye-b

192 y the connective tissues of the craniofacial skeleton, namely, bone and dentin with high expression l

193 reduce the rate at which corals build their skeletons, next-century acidification will also modify t

194 udies have investigated effects of OA on the skeleton of "classical" sea urchins (euechinoids), but t

195 and lactone subunits to assemble the complex skeleton of (-)-actinophyllic acid; and an unprecedented

196 The rigid bicyclic skeleton of 2,4-methanoprolines allowed us to follow the

197 om angiosperms, Pin p 1 contains the typical skeleton of 8 cysteine residues, important for its alpha

198 at a large number of sites within the axial skeleton of adult zebrafish.

199 a framework to consistently extract the main skeleton of an urban system and to further classify each

200 and chiral separation to form 27c, the core skeleton of cap piece 1.

201 Furthermore, the integrity of the skeleton of cidaroids has never been assessed, although

202 e the exquisitely preserved, nearly complete skeleton of Diandongosuchus fuyuanensis from the Middle

203 The [3,5,5,7] tetracyclic skeleton of echinopines has been stereoselectively acces

204 The synthesis of the carbon skeleton of filipin III, a polyenic macrolactone possess

205 uction of the 1,3-diazaspiro[4.4]nonane core skeleton of massadine and related dimeric pyrrole-imidaz

206 erate tumors after independently seeding the skeleton of mice.

207 This species has a reticulate, tufted skeleton of minute monaxon spicules, characteristic of t

208 bered aromatic heterocycles are a ubiquitous skeleton of pi-conjugated organic compounds, and their i

209 ric construction of the useful and important skeleton of the bicyclic N,O-acetals is described.

210 The skeleton of the compounds was synthesized by condensatio

211 ly preserved and mostly articulated juvenile skeleton of the diapsid reptile, Eusaurosphargis dalsass

212 rganic template structure within a carbonate skeleton of the foraminifera Orbulina universa using bot

213 atures of the ligand and metal composing the skeleton of the host framework are analyzed and shown to

214 olymeric core acting as a drug reservoir and skeleton of the nanoconstruct, phospholipid monolayer co

215 in which a thiophene ring is fused with the skeleton of the naturally occurring dye isatin.

216 xane (POSS) as the silica source to form the skeleton of the porous structure.

217 on conditions, which yielded the tetracyclic skeleton of the target compound with complete diastereos

218 ated with respect to their skeleton, and the skeleton of their primary spines is in direct contact wi

219 otably, compounds 8, 10, and 12 resemble the skeletons of 3-phenylisoindolin-1-ones.

220 cts dihydrobenzofuran, indoline, and chroman skeletons of biological significance in good to excellen

221 we undertook radiographic examination of the skeletons of Dolly and her contemporary clones.

222 as remained controversial because the distal skeletons of limbs and fins differ structurally, develop

223 ged ring systems, all of which are important skeletons of numerous biologically active natural produc

224 al structure of knobs in detergent-insoluble skeletons of P falciparum 3D7 schizonts.

225 e in the United States using cadaver-derived skeletons of people aged >/=50 y whose BMI at death was

226 was also assessed in archeologically derived skeletons of prehistoric hunter-gatherers and early farm

227 lete chemical space for the potential carbon skeletons of products from monoterpenoid synthases.

228 The carbon skeletons of terpenoids are generated through carbocatio

229 The sea urchin larval skeleton offers a simple model for formation of developm

230 xceptionally well, even when the rest of the skeleton or DNA in the organic fraction has decayed.

231 marrow stromal cells, but not from the axial skeleton or hypothalamic neurons, using Prx1-Cre.

232 in osteogenic lineage fate determination and skeleton patterning.

233 The mammalian skeleton performs a diverse range of vital functions, re

234 If this is how other corals form their skeletons, perhaps this is how a few corals survived pas

235 Position 6 of the morphinan skeleton plays a key role in the mu-opioid receptor (MOR

236 ced actin rings termed the periodic membrane skeleton (PMS).

237 gated the association between the peripheral skeleton-predicted failure load and stiffness, bone micr

238 used on dietary protein's role in the mature skeleton, prompted partly by an interest in nonpharmacol

239 assessment score of the uptake in the axial skeleton, proximal and distal limbs, liver, and spleen.

240 C control to give unknown fused heterocyclic skeletons, pyrrolo[3,2-c][1,2,4]triazolo[5,1-a] or [3,4-

241 )-dependent enzyme that catalyzes the carbon skeleton rearrangement of isobutyryl-CoA to butyryl-CoA.

242 We studied wing and pectoral skeleton reduction leading to flightlessness in the Gala

243 ed calcium carbonate mineralization for bulk skeleton reinforcement.

244 and that they attach to the surface of coral skeletons, remain amorphous for hours, and finally, crys

245 ne of the shortest routes to the full carbon skeleton reported to date.

246 carbonate fossils, well-preserved acroporid skeletons represent material with very high potential fo

247 in 20 of 25 regions of interest within a WM skeleton representing all major WM fasciculi.

248 compounds with a common decahydronaphthalene skeleton representing both cisoid and transoid enones we

249 3D printing of the injection molds and skeletons requires 3 h, seeding the muscle actuators tak

250 comparable fashion with the osteocyte in the skeleton, responding to changing tooth functions and end

251 However, almost nothing is known of the skeleton's physiology, and myriad questions about its st

252 the calicoblastic ectoderm and pre-existing skeleton, separated from the overlying seawater [2].

253 Voxelwise analysis of the brain white matter skeleton showed an average decrease of 0.0082 (Pmean = .

254 Strikingly, one Roman skeleton shows a clear signal of exogenous origin, with

255 Second, clonal composition in the skeleton significantly differed from extramedullary site

256 osis correlated with the SUVmax in the axial skeleton (spine and iliac crests) and proximal limbs.

257 The membrane skeleton strengthens the lipid bilayer and endows the me

258 ciparum infection contain a highly organized skeleton structure underlying a specialized region of me

259 resembling the expanded erythrocyte membrane skeleton structure, in the somatodendritic compartment.

260 These results suggest membrane skeleton structures are differentially regulated across

261 in these challenging movements, the internal skeleton, tendons and muscles involved were reconstructe

262 ged to sidestep the acquisition of the rigid skeleton that appears essential to the evolution of othe

263 bending specialised elements of the thoracic skeleton that are composites of the rubbery protein resi

264 ounting for the expansion/contraction of the skeleton that may occur via anchor protein diffusive mot

265 olecular dynamics model of the axon membrane skeleton that reproduces the structure identified by sup

266 propose, on the basis of close study of her skeleton, that her cause of death was a vertical deceler

267 Due to the bicyclo[2.2.2]octane skeleton, the steric environment around the carbene cent

268 e building units are integrated into the COF skeletons, the interlayer stacking becomes weak, resulti

269 hen coupled to a 3D printed flexible bio-bot skeleton, these actuators drive directional locomotion (

270 eletal structure that connects the flagellum skeleton through two membranes to the cytoskeleton.

271 n nanotubes (CNTs) were used as a conductive skeleton to anchor highly electrolytic manganese nanopar

272 DIK-1-1 is the only known Australopithecus skeleton to preserve all seven cervical vertebrae and pr

273 erse scaffolds, ranging from simple bicyclic skeletons to complex polycyclic systems and natural-prod

274 n be coupled to a wide variety of 3D-printed skeletons to power complex output behaviors such as cont

275 blocks in organic synthesis and an essential skeleton ubiquitously found in ligands, agrochemicals, a

276 eling, the physiological process whereby the skeleton undergoes continual cycles of formation and res

277 and because defects in the red cell membrane skeleton underlie multiple hemolytic anemias.

278 ated muscles and the spectrin-based membrane skeleton, use barbed and pointed-end capping proteins to

279 Ossification of the cranial skeleton varies from 20% in the smallest neonates to 90%

280 The chain lengths of isoprenoid carbon skeletons vary widely from neryl pyrophosphate (C10) to

281 an < .001) on average in 79% of white matter skeleton voxels.

282 ase of 0.0082 (Pmean = .002) in FA in 57% of skeleton voxels.

283 Among these organ groups, the skeleton was produced by fused deposition modeling (FDM)

284 ce the first primitive model of the red cell skeleton was proposed, many additional proteins have bee

285 oselective biosynthesis of over 50 diterpene skeletons was demonstrated, including natural variants a

286 ylates, including unprecedented heterocyclic skeletons, was performed by the transformation of methyl

287 s of these factors on the avian craniofacial skeleton, we conducted morphometric analyses on raptors,

288 omparison with strain maps of the developing skeleton, we identify canonical Wnt signalling as a cand

289 omeric body enclosing a microfabricated gold skeleton, we replicated fish morphology at 1/10 scale an

290 Improvements to the axial and appendicular skeletons were noticeable after 10 days of treatment and

291 e membrane is assembled, the dynamics of the skeleton when the membrane is deformed or perturbed by p

292 a dual origin: a strongly saddled porphyrin skeleton, which alleviates electrostatic repulsion betwe

293 ,1-a]pyrrolo[3,4-c]isoquinoline heterocyclic skeletons, which were further transformed into thermodyn

294 mosponges possessed biomineralized siliceous skeletons, which were subsequently lost and replaced by

295 14 patients with suspected infection of the skeleton who underwent (68)Ga-pentixafor PET/CT between

296 nsitivity and specificity for staging of the skeleton with either bone-specific PET/CT tracers, such

297 f new functionalities onto the resorcinarene skeleton with simultaneous generation of new stereogenic

298 ents, each involving a 1,2,4,6-heptatetraene skeleton with two variously located oxygen and/or nitrog

299 otential to afford complex polycyclic carbon skeletons with impressive efficiency, which are of high

300 G PET/MRI to assess malignant disease in the skeleton, with the possibility of taking advantage of th