ライフサイエンスコーパス: skip

1 e and function (e.g., intron retention, exon skipping).

2 action with the transcriptional co-regulator SKIP.

3 omain are important for the interaction with SKIP.

4 where the exon is normally almost completely skipped.

5 n the other two genotypes, where the exon is skipped.

6 sease course than those amenable to any exon skipping.

7 ic orientation that are favourable for water-skipping.

8 n to matched HC (n = 13) amenable to exon 51 skipping.

9 toring functional dystrophin protein by exon skipping.

10 annot compensate for SMN1 loss due to exon 7 skipping.

11 und that the majority resulted in total exon skipping.

12 proteins are synthesized by way of ribosomal skipping.

13 g domain, with alternative splicing and exon skipping.

14 y mimic those that would be achieved by exon skipping.

15 nscription rate causes an increase of exon 5 skipping.

16 exons 6 and 9 closer, thereby promoting exon skipping.

17 the transcriptional elongation rate and exon skipping.

18 alysis of clinical trials for exon 44 and 45 skipping.

19 n, and Sudemycins more acute effects on exon skipping.

20 on with these exonic sequences promotes exon skipping.

21 s to changes in stimulus duration) or period skipping.

22 current silent third base change, cause exon skipping.

23 lignancies to estimate the rate of said exon skipping.

24 ficient hDBR1 leads to a higher rate of exon skipping.

25 with different specificities to promote exon skipping.

26 ble precursors giving valuable, enantio-pure skipped 1,4-diene esters (with two configurationally def

27 gressed to the consecutive stage rather than skipping a stage.

28 No similar functional prion, skipping a stop codon, has been found in Escherichia col

29 dical problem (OR, 3.0; 95% CI, 1.6 to 5.9); skipping a test, treatment, or follow-up (OR, 2.1; 95% C

30 > C), previously described to cause exon 10 skipping (a truncating alteration), displays characteris

31 exons is widespread and correlates with exon skipping, a feature that adds considerably to the regula

32 , elastic spheres demonstrate superior water-skipping ability, but little is known about the effect o

33 istic explanation for the variations in exon-skipping activity and restoration of dystrophin protein

34 oligomers (PMOs) with glucose enhances exon-skipping activity in Duchenne muscular dystrophy (DMD) m

35 igher expression of hDBR1 only affected exon-skipping activity in malignant cells.

36 xpense of the inherent leading strand lesion skipping activity of the replisome, indicating that they

37 Exon skipping adds to the unexpected outcomes that must be ac

38 ted, c.[594-2A > C; 641A > G] caused exon 10 skipping, albeit not due to c.594-2A > C impairing the a

39 directing group) cascade transformations of skipped alkynes where the reactivity of the key radical

40 for two different Etaa1 mutations: an exon 2 skipping allele that deletes Gly78-Leu119, and a Cys166S

41 Antisense-oligonucleotide-induced exon skipping allows synthesis of partially functional dystro

42 ntly, a longer fasting period with breakfast skipping also increased the inflammatory potential of pe

43 ield lower levels of dystrophin than exon 51 skipping, although the resulting protein is functional e

44 across years was extremely high, even after skipping an entire seasonal migration.

45 19, CDC5, PRL1, and SPF27, as well as PRP17, SKIP and PPIL1.

46 studies revealed that it leads to mRNA exon skipping and ABCA4 protein truncation.

47 pre-mRNA is differentially spliced, via exon skipping and alternate 5'-splice donor sites, to yield f

48 ing in minigene assays, and resulted in exon skipping and an in-frame deletion of 40 amino acids in p

49 The mutation leads to exon skipping and deletion of 52-amino acid residues of a PX

50 The ASOs promote aberrant exon skipping and generation of premature termination codon (

51 I editing demonstrate that both the Alu exon skipping and inclusion isoforms encode active enzymes.

52 of novel transcriptomic events such as exon skipping and novel indels towards accurate downstream an

53 eotide conjugate designed to induce Dmd exon skipping and recover dystrophin protein expression cause

54 from variable (V) Igkappa exons promote exon-skipping and synthesis of V domain-less kappa light chai

55 Regulation of exon skipping and tandem alternative 3' splice sites (NAGNAGs

56 FLT3 resulted from complete or partial exon skipping and utilization of cryptic splice sites.

57 f MICA intron 4 leading to exon 3 and exon 4 skipping and/or deletions.

58 Here we show that an ensemble of BORC, Arl8, SKIP, and kinesin-1, previously shown to mediate centrif

59 correction of many genetic diseases via exon skipping, and the first AON-based drugs have entered cli

60 tation produce exon 33 skipping, exons 33-34 skipping, and WT VWF transcripts.

61 We report a pattern of skip-and-resurgence behavior between the years 2011 and

62 ryonic dystrophin in zebrafish using an exon-skipping approach severely impairs the mobility and musc

63 th other diseases that are eligible for exon-skipping approaches requiring whole-body treatment.

64 utations within the repeat that abolish exon skipping are corrected by compensatory mutations in the

65 The antisense oligonucleotides used for exon skipping are designed to bypass premature stop codons in

66 but alternative donor/acceptor site and exon skipping are mainly induced, indicating differential reg

67 ssing, alternative 5 and 3'ss usage and exon skipping are marked by distinct patterns of ordered intr

68 vascularization, capillary nonperfusion, and skip areas from previous laser treatment.

69 GCA-positive TAs contained viral antigen in skip areas, mostly in the adventitia and media and least

70 ns of key genes, including invected and even-skipped as markers for different stages of segment forma

71 ty, LaSSO identified both canonical and exon-skipping branch points.

72 A recommendation to eat or skip breakfast for weight loss was effective at changing

73 effectiveness of a recommendation to eat or skip breakfast on weight loss in adults trying to lose w

74 570 inconsistent breakfast consumers ate or skipped breakfast.

75 ut downstream eating behaviors subsequent to skipping breakfast in free-living individuals.

76 Skipping breakfast is associated with an increased odds

77 Skipping breakfast is considered a frequent and unhealth

78 ompared with high-energy breakfast, habitual skipping breakfast was associated with a higher prevalen

79 health effects of specific eating patterns: skipping breakfast, intermittent fasting, meal frequency

80 y energy intake (70% of the population); and skipping breakfast, when consuming <5% of total daily en

81 likely to reach adulthood, recruit late and skip breeding often but have the highest adult survival

82 Exon skipping by ASOs is gaining traction as a therapeutic st

83 alpha-chain mRNA splicing and favors exon 9 skipping by reducing the binding of the splicing enhance

84 We have now expanded the potential for exon skipping by testing whether an internal, in-frame trunca

85 These pathways include lesion skipping by the replisome, replication fork regression f

86 expressed by cancer cells with MSI, via exon skipping caused by somatic deletions in the T(17) intron

87 found that rs10401969 regulates SUGP1 exon 8 skipping, causing non-sense-mediated mRNA decay.

88 entral striatum in rats encountering wait or skip choices for delayed delivery of different flavors u

89 H-binding GGGGG motif are predisposed to be skipped compared to those carrying the SRSF1-binding GGA

90 subpg/mL sensitivities to be reached and to skip conventional and time-consuming chromatographic sep

91 muscle disease and showed that multiple exon skipping could be induced in RNA that encodes a mutant h

92 but also increased expression of an exon 10-skipped CYP24A1 splice variant; in a minigene model the

93 ar trafficking correspond well with the exon-skipping data, with higher activity in myotubes than in

94 fat, and protein, respectively): a breakfast skipping day (BSD) and a dinner skipping day (DSD) separ

95 a breakfast skipping day (BSD) and a dinner skipping day (DSD) separated by a conventional 3-meal-st

96 , 24-h energy expenditure was higher on both skipping days (BSD: +41 kcal/d; DSD: +91 kcal/d; both P

97 s with deletions amenable to exons 44 and 46 skipping declined at a slower rate over 2 years (9 units

98 e muscular dystrophy, the rationale for exon skipping derived from observations in patients with natu

99 lkoxide reductants provides direct access to skipped diene products.

100 d internal alkynes leads to the formation of skipped dienes containing trisubstituted alkenes.

101 Synthesis of skipped dienes through the hydroallylation of terminal a

102 This was utilized to synthesize a series of skipped dienes, a class of compounds that are prevalent

103 tely 80% cis), whereas species-specific exon skipping differences are driven by both cis- and trans-r

104 to be useful synthetic handles, and 3-amino skipped diynes are convenient building blocks for enanti

105 Cu-catalyzed synthesis of nonracemic 3-amino skipped diynes via an enantiodetermining C-C bond format

106 d stereoselectivity inherent to these chiral skipped diynes, the reaction tolerates an extremely broa

107 less likely to complete wP and ddAC without skipped doses, dose modification, or early discontinuati

108 aucoma who reported taking smaller doses and skipping doses owing to cost dropped from 9.4% and 8.2%

109 on because gene splicing analysis shows exon skipping due to loss of the ESE.

110 ircuit of sense-antisense pairs and the exon skipping during alternative splicing, through interactin

111 We find that the skipping dynamics are governed by the wave propagation s

112 n normal adult tissues as a result of exon 6 skipping, enhanced exon 6 inclusion leads to expression

113 expression of the spider orthologues of even-skipped (eve) and runt-1 (run-1), at least in part via c

114 targets for Islet (Isl), Lim3, Hb9, and Even-skipped (Eve) identifies both ion channel genes and gene

115 e, we explore how the Drosophila erecta even-skipped (eve) locus has evolved by testing its activity

116 ds to examine the dynamic regulation of even-skipped (eve) stripe 2 expression in the precellular Dro

117 ed that Hb bifunctionally regulates the even-skipped (eve) stripe 3+7 enhancer (eve3+7) in Drosophila

118 PESE is also repressed by Even-skipped (Eve), but, of interest, this repression involve

119 Particularly, exon-skipping event in Enhancer of Zeste Homologue 2 (EZH2) a

120 omplex PRC2, and the down-regulation of exon-skipping event may lead to the regain of functional EZH2

121 Both transcript isoforms from this skipping event site, i.e. in which the exon is either in

122 ing scanner (GESS), for de novo detection of skipping event sites from raw RNA-seq reads without prio

123 One particular mode of AS is the skipping event where an exon may be alternatively exclud

124 plice variants of KV10.1 resulting from exon-skipping events (E65 and E70) in human brain and cancer

125 ew target function for AS prediction in exon skipping events and show it significantly improves model

126 identified by CoSREM may play a role in exon skipping events in several tumor samples.

127 Exon-skipping events increased in cells deficient for the nuc

128 Interestingly, 29 exon-skipping events induced by treatment were identified and

129 On the other hand, exon skipping events were rare in coding regions (1%) but enr

130 ll annotated introns, hundreds of novel exon-skipping events, and thousands of novel introns.

131 s, but also pinpointed novel, but rare, exon-skipping events, which may reflect aberrantly spliced tr

132 force algorithms to detect all possible exon-skipping events, which were widespread but rare compared

133 xon-intron boundary establishment leading to skipping events.

134 in pre-mRNA splicing with prevalence of exon skipping events.

135 Cell types other than photoreceptors skip exon 2A from the mature BBS8 transcript, which rend

136 cantly identified protein-coding genes, with skipped exon and alternative first exon being the most f

137 Examination of splice isoforms revealed skipped exon and retained intron to be the most abundant

138 Sequences surrounding cassette exons of skipped exon events are enriched for motifs bound by the

139 DTNA gene produces a novel splice site which skips exon 21 and leads to a shorter alternative transcr

140 essed as an alternative spliced isoform that skips exon 9, resulting in a premature stop codon predic

141 pausing signatures that differ markedly from skipped exons, indicating an intrinsic capacity for Pol

142 r non-functional 'minus beta' isoform, which skips exons 7 and 8.

143 for the c.5842+1G>C mutation produce exon 33 skipping, exons 33-34 skipping, and WT VWF transcripts.

144 lly, we also show that PLEKHM1 competes with SKIP for Arl8b binding, which dictates lysosome position

145 of CD46 cassette exon 13, whose inclusion or skipping generates different cytoplasmic tails with dist

146 Meal skipping has become an increasing trend of the modern li

147 n for populations to recover than 'hop' and 'skip' (high or medium frequency stopover) migrants.

148 s.We investigated whether the timing of meal skipping impacts these risks by affecting circadian regu

149 iation (that is, more insolation peaks were 'skipped'), implying that the energy threshold for deglac

150 nscripts by both directly increasing exon 13 skipping in an allele-related manner and specifically st

151 were shown to cause intron retention or exon skipping in an allele-specific manner, with approximatel

152 Given the success of exon skipping in clinical trials to treat genetic diseases su

153 idespread intron retention and cassette exon skipping in leukemic cells regardless of Srsf2 genotype,

154 t these CD33 SNPs are associated with exon 2 skipping in leukocytes from AML patients and with a nove

155 n by antisense oligonucleotide-mediated exon-skipping in mdx mice and (2) stable restoration of alpha

156 equence and is tightly regulated in favor of skipping in neurons; however, its biological function is

157 ce site recognition and contributing to exon skipping in nonneural cells.

158 : the novel PSEN1 variant resulted in exon 9 skipping in patient's RNA, leading to a pathogenic misse

159 to a silencer (ESS), causing frequent exon7 skipping in SMN2 pre-mRNA and yielding a truncated prote

160 n a reduction of dystrophin protein and exon skipping in the diaphragm.

161 binding site could efficiently induce exon 9 skipping in the presence of the G allele, and thereby re

162 mic outbreak in 2011/12 failed to occur (or "skipped") in many countries across the globe, although a

163 hing and differential exon usage (i.e., exon-skipping), in addition to its effects on gene expression

164 involved in the regulation of HMGCR exon 13 skipping, in a founder population and in two distinct mi

165 ls after lunch.Compared with 3 meals/d, meal skipping increased energy expenditure.

166 herapeutic restoration of dystrophin by exon skipping induced widespread shifts in protein and mRNA e

167 deglaciation threshold and in the number of skipped insolation peaks.

168 identified the evolutionarily conserved Even-skipped(+) interneurons (Eve/Evx).

169 can be placed into four major classes: exon skipping, intron retention, alternative 5' splice sites,

170 Exon skipping is a promising therapeutic strategy for Duchenn

171 mprove this therapeutic approach to DMD.Exon skipping is a strategy for the treatment of Duchenne mus

172 Exon skipping is considered a principal mechanism by which eu

173 Exon skipping is currently being tested in humans with dystro

174 Although SMN2 exon skipping is the principal contributor to SMA severity, m

175 er included (inclusion isoform) or excluded (skipping isoform), are typically present in one cell, an

176 We show that Even-skipped lateral interneurons (ELs) are sensory processin

177 d that the c.893-1G>A mutation causes exon 7 skipping leading to deletion of 65bp, predicted to resul

178 ndings of extensive aphthous ulceration with skip lesions extending to the terminal ileum, and histol

179 involvement, and the presence or absence of skip lesions.

180 ecific CPP-PMOs demonstrated comparable exon skipping levels for both pre-mRNA targets when compared

181 nt recombination events, and using augmented skip lists to represent tracked genetic segments.

182 r meals are difficult to distinguish because skipping meals and snacking have become more prevalent.

183 urrent in lung adenocarcinoma and cause exon skipping (METDelta14).

184 If adaptation depends on proximity, hop and skip migrants' populations can recover but jump migrants

185 hese insights, we explain why softer spheres skip more easily than stiffer ones.

186 To correct DMD by skipping mutant dystrophin exons in postnatal muscle tis

187 d family with a heterozygous in-frame exon 9 skipping mutation (c.835+2T>G) and in a CVID-affected fa

188 hogenic allele in exon 41, including an exon-skipping mutation that induced an in-frame deletion.

189 er, 12 to 21 per cent of enhancers appear to skip non-expressed neighbours and regulate a more distal

190 ion mechanism, we synthesized conjugated and skipped nonconjugated cholestadienols that would give on

191 aries and explains the aetiology of the even-skipped null mutant phenotype.

192 However, the Nasonia pair-rule genes even-skipped, odd-skipped, runt and hairy are all expressed a

193 lear ribonucleoprotein H-dependent inclusion/skipping of a PRKCA alternative exon 3*.

194 ults in alternative splicing (AS), including skipping of an exon in amyotrophic lateral sclerosis (AL

195 e of PRRC2C, SRSF1 downregulation led to the skipping of an exon overexpressed in primary lung tumors

196 ly shown that these SNPs are associated with skipping of CD33 exon 2 in brain mRNA.

197 ice with morpholino oligomers to induce exon skipping of dystrophin exon 23 (that results in function

198 45 (Delta45)-may theoretically be treated by skipping of either flanking exon (44 or 46).

199 that results in a splicing defect leading to skipping of exon 11 (p.Lys333Lysfs*3).

200 In the absence of ELAVL1, skipping of exon 11 of Eif4enif1 forms the stable, short

201 the frameshift p.Lys645AlafsTer12 and/or the skipping of exon 11 that results in deletion of 30 highl

202 erited a splice-site variant that results in skipping of exon 13, p.Ile459Profs( *)4 (not reported in

203 th endplate AChE deficiency causes exclusive skipping of exon 16.

204 KBKAP gene that results in a tissue-specific skipping of exon 20 and a corresponding reduction of the

205 o additional novel transcripts involving the skipping of exon 3 or exons 3, 4, and 5 and are referred

206 Patient-derived PPCs showed skipping of exon 39 or exons 39 and 40 in the mRNA.

207 conclude that in DMD patients with Delta45, skipping of exon 44 and multiexon skipping of exons 46 a

208 s 46-48) are better potential therapies than skipping of exon 46 alone.

209 to those of full-length channels (Cav1.4FL), skipping of exon 47 dramatically alters Cav1.4 function.

210 ense oligonucleotide-mediated (ASO-mediated) skipping of exon 6 decreased MDM4 abundance, inhibited m

211 a duplicate gene (SMN2) primarily results in skipping of exon 7 and production of an unstable protein

212 ompensate for this deficiency because of the skipping of exon 7 during pre-messenger RNA (mRNA) proce

213 h causes premature protein truncation due to skipping of exon 7.

214 ls to compensate for the loss of SMN1 due to skipping of exon 7.

215 site mutation (c.730+4A>G), causing in-frame skipping of exon 8.

216 h Delta45, skipping of exon 44 and multiexon skipping of exons 46 and 47 (or exons 46-48) are better

217 g cDNA showed the splice site variant led to skipping of exons 6 of the FHL1A isoform, equivalent to

218 nne muscular dystrophy, we propose that exon skipping of FcepsilonRIbeta is a potential approach for

219 Consistently, we show that skipping of MKK7 exon 2 enhances JNK pathway activity, a

220 disrupted the developmentally regulated exon skipping of Ndel1 mRNA, which is bound by MBNL1 and crit

221 scination and engineering application, water-skipping of rigid stones and spheres has received consid

222 calcium levels induce robust and reversible skipping of several alternative exons from endogenously

223 euron 1 (SMN1) gene coupled with predominant skipping of SMN2 exon 7.

224 The skipping of some exons may be more efficacious than othe

225 s significantly on those genes, resulting in skipping of the alternative exons.

226 sing antisense oligonucleotide-mediated exon skipping of the beta-subunit of the high-affinity IgE re

227 in a PTBP1-binding site that disrupts normal skipping of the FLNA poison exon in NPCs and causes a br

228 es an autoinhibitory domain, induces partial skipping of the in-frame exon and nuclear accumulation o

229 on induced by histone depletion promotes the skipping of variable exons in the CD44 gene.

230 pproach for the controlled transformation of skipped oligoalkynes into polycyclic ribbons of tunable

231 nd regioselectivity of the initial attack in skipped oligoalkynes is controlled by propargyl OR moiet

232 Here using exon skipping oligonucleotides we predominantly restored dyst

233 talizations and emergency department visits; skipped or delayed medical care; usual source of care; d

234 near the 3' splice site promoted either exon skipping or inclusion.

235 e single-guide RNAs (sgRNAs) can induce exon skipping or large genomic deletions that delete exons.

236 uencing regulatory elements, leading to exon skipping, or by creating a new cryptic splice site.

237 At low temperatures, we observed caustics of skipping orbits extending over hundreds of superlattice

238 ation dynamics, we further observed both the skipping orbits of excited atoms traveling down the syst

239 ced adhesions sequentially without having to skip over gaps in adhesive area, biases protrusion forma

240 nuniform sampling (NUS) obtained by randomly skipping points in the first dimension corresponding to

241 Drug-induced exon skipping preferentially affects shorter alternatively sp

242 cing modulator-induced intron-retention/exon-skipping profile, which correlates with the differential

243 as extent of spread, with silencing able to skip regions.

244 Odd-skipped related 1 (Osr1) encodes a zinc finger transcrip

245 Previous studies have identified the odd-skipped related 2 (Osr2) transcription factor as a key i

246 sion synthesis came at the expense of lesion-skipping replication restart.

247 shows that the functional importance of each skip residue is associated with rod position and reveals

248 In contrast, the last skip residue region constitutes a true molecular hinge,

249 SH3-binding region of paramyosin contains a "skip residue," which is likely to locally unwind the coi

250 olecular characterization of the four myosin skip residues also provides a guide to modeling the effe

251 Assembly of myosin with mutated skip residues in cardiomyocytes shows that the functiona

252 that the regions surrounding the first three skip residues share high structural similarity despite t

253 nd is characterized by the insertion of four skip residues that introduce discontinuities in the coil

254 Near each of these skip residues, the coiled-coil transitions to a nonclose

255 AON-induced exon skipping resulted in specific Alk4 down-regulation, inhi

256 he Nasonia pair-rule genes even-skipped, odd-skipped, runt and hairy are all expressed as early blast

257 novel computational method, graph-based exon-skipping scanner (GESS), for de novo detection of skippi

258 site are imprecise as reverse transcriptase skips several nucleotides while traversing a 2-5 linkage

259 l not capture the fitness benefits gained by skipping sexual reproduction.

260 tations at splice junctions often cause exon skipping, short deletions, or insertions in the mature m

261 The subset of patients amenable to exon 51 skipping showed a more severe disease course than those

262 sortium and experimentally validated several skipping site predictions by RT-PCR.

263 polyphosphate-5-phosphatase K, also known as SKIP (skeletal muscle and kidney enriched inositol phosp

264 fish are spawning in an alternate location, skip-spawning, or not spawning until an older age affect

265 identical trains of stimuli, except for one skipped stimulus, and found that EPSC amplitude was affe

266 amplitude was affected for 60 ms following a skipped stimulus.

267 (ii) Base-level errors can be skipped; structural errors need to be detected and corre

268 s and increased fat oxidation with breakfast skipping suggest the development of metabolic inflexibil

269 f shelterin components, which allows CLRC to skip telomeric repeats to internal regions.

270 in patients with mutations amenable to exon skipping than in those not amenable.

271 xhibited consolidated locomotor activity and skipped the timed rest period (siesta) present in wild-t

272 role is to funnel a rough folding landscape, skipping the accumulation of kinetic traps, providing a

273 striking contrast to Pol lambda, Pol micro "skips" the first available template nucleotide, instead

274 three families and was shown to induce exon skipping; the other mutations were frameshift mutations

275 Exon-skipping therapies aim to convert Duchenne muscular dyst

276 eletions and insertions are targeted by exon-skipping therapies.

277 mers (PMOs) has shown great promise for exon-skipping therapy of Duchenne Muscular Dystrophy (DMD).

278 deno-associated virus (AAV)-U7-mediated exon-skipping therapy was shown to decrease drastically after

279 implications for the development of DMD exon-skipping therapy.

280 Although very effective in correcting exon skipping, they also induced retention of the short downs

281 also affects splicing by facilitating exon 2 skipping, thus also being in effect a loss-of-function a

282 lement, the subjects completed 6 min of rope-skipping to stimulate collagen synthesis.

283 We introduce suffix skips to traverse several suffix links simultaneously an

284 These exon-skipping transcripts are therefore unlikely to be functi

285 The pervasive exon-skipping transcripts were stochastic, did not increase i

286 pe 1 VWD through mRNA degradation of exon 38 skipping transcripts.

287 nistration was initiated, the TAC dosage was skipped until trough levels began to decline; it was the

288 Exon skipping uses antisense oligonucleotides (ASOs) to alter

289 Exon skipping uses antisense oligonucleotides as a treatment

290 corresponding to LBD to produce namely exon-skipping variants.

291 The average splicing rate by exon skipping was approximately 0.24% in wild type and approx

292 ly from on-target integration, and ribosomal skipping was highly efficient.

293 To prevent exon-skipping, we have targeted an intronic repressor, Elemen

294 mitant with T cell activation-induced exon 5 skipping, we observed a downregulation of SRSF1.

295 polymerase chain reaction to detect exon 14 skipping were performed where sufficient tissue was avai

296 were >/=7 years old and amenable to exon 51 skipping were randomized to eteplirsen (30/50mg/kg) or p

297 regulated exons PTBP1 tends to promote their skipping, whereas binding to downstream sites often stim

298 d reading frame upstream of the IRES by exon skipping, which led to synthesis of a functional N-trunc

299 Exon 44 or 45 skipping will likely yield lower levels of dystrophin th

300 ion of Osr1, a homolog of the Drosophila odd-skipped zinc-finger transcription factor, in the undiffe