ライフサイエンスコーパス: sleep deprivation

1 ep, spontaneous wake, and forced wake (acute sleep deprivation).

2 behavioral adjustment to a novel task after sleep deprivation.

3 ignore neutral distracting information after sleep deprivation.

4 during sleep, wake, and after short or long sleep deprivation.

5 s the elevated Abeta accumulation induced by sleep deprivation.

6 in phagocytosis, are upregulated after acute sleep deprivation.

7 inhibition and antisaccades-that occur after sleep deprivation.

8 heir active period and in response to forced sleep deprivation.

9 bserved with respect to both time of day and sleep deprivation.

10 ants and also in wild type animals following sleep deprivation.

11 IP cannot recover sleep after the night-time sleep deprivation.

12 restriction, and following subsequent acute sleep deprivation.

13 pus-dependent learning tasks associated with sleep deprivation.

14 e for the memory impairments associated with sleep deprivation.

15 r their membrane excitability in response to sleep deprivation.

16 elevated arousal threshold and resistance to sleep deprivation.

17 s wake, chronic sleep restriction, and acute sleep deprivation.

18 activity, and food, during a period of total sleep deprivation.

19 Both involve short-term sleep deprivation.

20 ferent from those observed after acute total sleep deprivation.

21 , and intensifies the effects of acute total sleep deprivation.

22 as television watching, alcohol intake, and sleep deprivation.

23 way secretions, gastroesophageal reflux, and sleep deprivation.

24 eep, and reduced the homeostatic response to sleep deprivation.

25 rodents subjected to 1 night of paradoxical sleep deprivation.

26 aintain optimal cognitive functioning during sleep deprivation.

27 icits in short-term memory following 12 h of sleep deprivation.

28 reased in response to normal wakefulness and sleep deprivation.

29 d REM sleep duration following selective REM sleep deprivation.

30 when methylphenidate was administered after sleep deprivation.

31 r modafinil 200 mg (n = 20) after 1 night of sleep deprivation.

32 ndeed, dopamine release was increased during sleep deprivation.

33 tant dim light, hourly isocaloric meals, and sleep deprivation.

34 ufficient to prevent learning deficits after sleep deprivation.

35 amine the clinical and behavioral effects of sleep deprivation.

36 ly, prevents learning impairments induced by sleep deprivation.

37 account of one-choice RT under conditions of sleep deprivation.

38 hapes of RT distributions over the course of sleep deprivation.

39 isplaying diminished sleep rebound following sleep deprivation.

40 of the cognitive/behavioral consequences of sleep deprivation.

41 sleep-induced ATP surge than during wake or sleep deprivation.

42 ective fatigue-related measures during total sleep deprivation.

43 eep and in cognitive impairments that follow sleep deprivation.

44 o compensatory or "homeostatic" responses to sleep deprivation.

45 g, whereas this was not observed after acute sleep deprivation.

46 tributes to REM sleep recovery following REM sleep deprivation.

47 attentional strategy and/or compensation to sleep deprivation.

48 the circadian clock but is also affected by sleep deprivation.

49 d with sleep pressure induced by 2 or 4 h of sleep deprivation.

50 ring sleep and this decline was prevented by sleep deprivation.

51 ssions, including a session after full-night sleep deprivation.

52 arousal in flies counteracts the effects of sleep deprivation.

53 m potentiation (LTP) due to saturation after sleep deprivation.

54 naptic plasticity phenotypes associated with sleep deprivation.

55 aling and cognitive deficits associated with sleep deprivation.

56 account for the increase in SWA that follows sleep deprivation.

57 evoked potential and memory formation) after sleep deprivation.

58 TP-like plasticity in humans after sleep and sleep deprivation.

59 nitive susceptibility to, and recovery from, sleep deprivation.

60 nd impairments in long-term memory caused by sleep deprivation.

61 uestionnaire-based) across 10 hours of acute sleep deprivation (10:00 PM to 8:00 PM.

62 estricted sleep (n = 13) or 1 night of total sleep deprivation (24 hours of wakefulness) (n = 13).

63 During sleep deprivation, 27 metabolites (tryptophan, serotonin

64 Furthermore, the response to acute sleep deprivation (6 h) was significantly attenuated in

65 episodic memory traces in REM sleep, and REM sleep deprivation affecting hippocampus-independent emot

66 We asked if sleep deprivation affects advice taking.

67 Sleep deprivation affects phosphorylation of regulatory

68 These results suggest that a night of total sleep deprivation affects the neural mechanisms underlyi

69 EG and fMRI tasks, we were able to show that sleep deprivation alters emotional reactivity by trigger

70 nce imaging (fMRI), here we demonstrate that sleep deprivation amplifies reactivity throughout human

71 eduled sleep - and this was followed by 40 h sleep deprivation and 8 h scheduled recovery sleep.

72 /or sleep duration or performed experimental sleep deprivation and assessed inflammation by levels of

73 Both sleep deprivation and caffeine treatment potentiated lig

74 Both sleep deprivation and caffeine treatment potentiated lig

75 Contrary to nocturnal rodents, both sleep deprivation and caffeine-induced arousal potentiat

76 irst of metabolic profiling during sleep and sleep deprivation and characterization of 24 h rhythms u

77 pite mounting evidence that both acute total sleep deprivation and chronically restricted sleep degra

78 Sleep deprivation and circadian disruption underlie mood

79 during the day and its deterioration during sleep deprivation and circadian misalignment.

80 nipulation of glymphatic activity, including sleep deprivation and cisternotomy, suppressed or elimin

81 ter spontaneous wake and short-term (3-24 h) sleep deprivation and decreases during sleep.

82 y explain the antidepressive effect of acute sleep deprivation and deserve further study.

83 Here, we provide direct evidence linking sleep deprivation and false confessions.

84 Sleep deprivation and fatigue are common subjective comp

85 lity in 15 healthy male adults after 52 h of sleep deprivation and following 14 h of recovery sleep.

86 or lapses in performance under conditions of sleep deprivation and for changes in the shapes of RT di

87 in lysolipids were found both in vivo after sleep deprivation and in vitro after stimulation, strong

88 ep-promoting MB microcircuit is increased by sleep deprivation and is necessary for homeostatic rebou

89 Additionally, the association between sleep deprivation and metabolic disorders such as diabet

90 ed to irregular sleep schedules resulting in sleep deprivation and misalignment of circadian rhythms,

91 ribute to the brain's coping mechanisms with sleep deprivation and point to a novel target to improve

92 Sleep deprivation and rebound were accompanied by signif

93 We quantified effects of sleep, sleep deprivation and recovery sleep on whole-body total

94 al activation throughout the neuraxis during sleep deprivation and recovery.

95 is upregulated already after a few hours of sleep deprivation and shows a further significant increa

96 ehavioral manifestations of sleep, wake, and sleep deprivation and specific measurable changes in the

97 Sleep deprivation and stress are known to alter immune f

98 systematically manipulating the durations of sleep deprivation and subsequent recovery sleep, we show

99 f altered metabolic signaling in response to sleep deprivation and suggest that these signaling pathw

100 ger for enhanced adenosine release following sleep deprivation and suggest that this induction may co

101 by approximately 7% during the first 24 h of sleep deprivation and was significantly decreased by app

102 nscriptome data were collected under normal, sleep-deprivation and abnormal sleep-timing conditions t

103 llect articles relating television watching, sleep deprivation, and alcohol consumption to food intak

104 M transitions, hindered recovery sleep after sleep deprivation, and impaired memory.

105 , endogenous ecdysone levels increased after sleep deprivation, and mutants defective for ecdysone si

106 sleep duration and intensity following total sleep deprivation, and rebounds in both NREM sleep inten

107 gnaling transmits changes in aggression upon sleep deprivation, and reduced aggression places sleep-d

108 well-established negative health outcomes of sleep deprivation, and the suggestion that availability

109 ebo) did not differ between rested sleep and sleep deprivation, and were associated with the increase

110 ermine brain mechanisms of action underlying sleep deprivations antidepressant effects, we examined i

111 ether the cognitive deficits associated with sleep deprivation are caused by attenuated cAMP signalin

112 Lifestyles involving sleep deprivation are common, despite mounting evidence

113 sual or hearing impairment, dehydration, and sleep deprivation are effective for delirium prevention

114 ence or absence of sleep and the response to sleep deprivation are highly relevant when identifying b

115 hat television watching, alcohol intake, and sleep deprivation are not merely correlated with obesity

116 processes restore learning ability following sleep deprivation are similarly unknown.

117 he single neuron level, we find that chronic sleep deprivation, as well as Abeta expression, enhances

118 Sleep and sleep deprivation bidirectionally alter molecular signal

119 ride after rested sleep and after 1 night of sleep deprivation; both after placebo and after methylph

120 Moreover, sleep deprivation brings about vehicle accidents and med

121 tial deficits in short-term memory following sleep deprivation but retain their ability to learn afte

122 lects every-day sleep loss better than acute sleep deprivation, but its effects and particularly the

123 port non-specific triggers such as stress or sleep deprivation, but only rarely do seizures occur as

124 We simulate sleep deprivation by introducing a drive to the MA, whic

125 ila melanogaster males, sleep pressure after sleep deprivation can be counteracted by raising their s

126 w that a brief period (3 h) of selective REM sleep deprivation caused REM sleep rebound associated wi

127 sely fit group-average PVT data during acute sleep deprivation, chronic sleep restriction, and recove

128 ing more significant (Cohen's d = 1.03) than sleep deprivation (Cohen's d = 0.49) and television watc

129 sleep restriction and after 1 night of acute sleep deprivation compared to a regular sleep condition

130 t metabolites significantly increased during sleep deprivation compared with sleep (taurine, formate,

131 or availability in the ventral striatum with sleep deprivation (compared with rested sleep) that was

132 Together, these findings establish that sleep deprivation compromises the faithful signaling of,

133 The state of sleep deprivation continues to be associated with malada

134 , and homeostatic sleep-pressure response to sleep deprivation correlated negatively with the decreas

135 g/mL (95% CI [0.94, 49.6], P = .04), whereas sleep deprivation counteracted this decrease.

136 3 consecutive days, the second day being the sleep deprivation day.

137 In mice, we find that five hours of sleep deprivation decreases dendritic spine numbers sele

138 Five hours of total sleep deprivation directly following training impaired t

139 We demonstrate that sleep deprivation downregulates the expression of microR

140 Sleep deprivation during the night facilitates MIP secre

141 ith the perplexing antidepressant benefit of sleep deprivation, elevating mood in a proportion of pat

142 esting state human EEG data during a 40-hour sleep deprivation experiment by evaluating the decay in

143 ates of sleep homeostasis in sheep through a sleep deprivation experiment.

144 of genes that responded to subsequent total sleep deprivation from 122 to 856.

145 vicanthis ansorgei, were aroused at night by sleep deprivation (gentle handling) or caffeine treatmen

146 was shown between the unrestricted sleep and sleep deprivation group (95% CI [3.4, 148.4], P = .04).

147 In the sleep deprivation group, BMI and central distribution of

148 differed between the unrestricted sleep and sleep deprivation groups (P = .04) in contrast to stable

149 Moreover, the adolescents with sleep deprivation had a lower median (interquartile rang

150 ors-television watching, alcohol intake, and sleep deprivation-had significant short-term effects on

151 Sleep deprivation has been shown recently to alter emoti

152 Sleep and sleep deprivation have long been recognized to influence

153 During sleep deprivation, homeostatic and circadian processes i

154 or delirium, including cognitive impairment, sleep deprivation, immobility and visual and hearing imp

155 Here, we demonstrate in humans that sleep deprivation impairs both viscerosensory brain (ant

156 At the cellular level, sleep deprivation impairs cellular excitability necessar

157 Although previous work has indicated that sleep deprivation impairs hippocampal cAMP signaling, it

158 Sleep deprivation impairs many cognitive abilities, but

159 Sleep deprivation impairs the formation of new memories.

160 rpret variation in performance levels during sleep deprivation in a way that is qualitatively consist

161 manic or hypomanic symptoms to emerge after sleep deprivation in bipolar disorder raises questions a

162 Sleep deprivation in early night, but not late night, po

163 eview data on the psychotomimetic effects of sleep deprivation in healthy human beings and provide ev

164 nces alone may worsen pain, and experimental sleep deprivation in humans supports this claim.

165 We explored the effects of 10 days of sleep deprivation in rats on the expression of striatal

166 iurnal rodent, the Grass rat, indicates that sleep deprivation in the early rest period induces phase

167 1 neurons are still activated in response to sleep deprivation in these mice but, in the absence of n

168 cific Nlg1 transcript variants is changed by sleep deprivation in three mouse strains.

169 induced increase in alpha power by means of sleep deprivation increased the average duration of indi

170 reduced and fragmented sleep, while chronic sleep deprivation increases Abeta burden.

171 for a scientific commentary on this article.Sleep deprivation increases amyloid-beta, suggesting tha

172 We hypothesize that chronic sleep deprivation increases cerebral Abeta42 levels, whi

173 Sleep deprivation increases the excitability of dorsal F

174 othesis that sleep conserves energy and that sleep deprivation increases total daily EE in humans.

175 intenance of sleep amount or depth following sleep deprivation, indicates that sleep and sleep-like s

176 n of GS and innexin2 are increased following sleep deprivation, indicating that GS and innexin2 genes

177 Sleep deprivation induced a global increase in mGluR5 bi

178 Early night, but not late night, sleep deprivation induced a significant phase shift.

179 results suggest a possibility of normalizing sleep deprivation-induced abnormal reward seeking by tar

180 s at understanding the mechanisms underlying sleep deprivation-induced enhancement of reward seeking.

181 s increase correlated significantly with the sleep deprivation-induced increase in subjective sleepin

182 Finally, the sleep deprivation-induced increase in well established n

183 IMK-cofilin activation-signaling pathway for sleep deprivation-induced memory disruption and reductio

184 ogether, these results reveal a novel set of sleep deprivation-induced transcriptional changes in rew

185 Sleep deprivation induces changes in brain metabolism an

186 Sleep deprivation is a major source of morbidity with wi

187 ns, one of the most profound consequences of sleep deprivation is imprecise or irrational communicati

188 Rebound sleep following sleep deprivation is reduced by activation of sNPF neuro

189 e in the decreased alertness associated with sleep deprivation is unclear.

190 ough it does not involve circadian shifts or sleep deprivation, it markedly alters feeding behaviors

191 the clinic: electroconvulsive shock therapy, sleep deprivation, ketamine, scopolamine, GLYX-13 and pi

192 Sleep deprivation leads to increased hippocampal express

193 In unaffected sheep, sleep deprivation led to increased EEG delta (0.5-4 Hz)

194 Sleep deprivation (<8 hours of sleep per night) is assoc

195 e population into 2 groups: adolescents with sleep deprivation (<8 hours/night) and adolescents with

196 s in some frequency bands over the course of sleep deprivation may falsely indicate LRTC changes that

197 As such, it has been suggested that sleep deprivation may reduce posttraumatic stress disord

198 These data support the use of the sleep deprivation model in combination with biomarkers w

199 These findings suggest that prolonged sleep deprivation modifies inflammatory and cholesterol

200 The adolescents with sleep deprivation (n = 257) compared with those with ade

201 cantly increased by approximately 32% on the sleep deprivation night and significantly decreased by a

202 Neither experimental sleep deprivation nor sleep restriction was associated w

203 Together, these data support a view that sleep deprivation not only is associated with enhanced r

204 nterrelationship among circadian disruption, sleep deprivation, obesity, and diabetes and implication

205 Sleep deprivation of HD model flies results in exacerbat

206 urs (sleep control) and once after 33 hours (sleep deprivation) of controlled wakefulness.

207 t frequent reasons for wanting to leave were sleep deprivation on a specific rotation (50.0%), an und

208 experimental study to examine the effects of sleep deprivation on advice taking in an estimation task

209 However, a clear effect of sleep deprivation on aggressive behaviors remains unclea

210 However, the detrimental impact of sleep deprivation on central brain mechanisms governing

211 may underlie some of the negative effects of sleep deprivation on cognitive performance and is consis

212 e effects of 3 consecutive nights of partial sleep deprivation on components of energy balance.

213 e, we examine the impact of brief periods of sleep deprivation on dendritic structure.

214 extremes of sleep duration, and experimental sleep deprivation on genomic, cellular, and systemic mar

215 lecular mechanisms underlying the effects of sleep deprivation on HSCs, emphasizing the potentially c

216 nderlie some of the negative consequences of sleep deprivation on memory and other cognitive function

217 and conversely, resilience) to the impact of sleep deprivation on memory formation.

218 metabolomics to examine the effect of acute sleep deprivation on plasma metabolite rhythms.

219 This study demonstrates the impact of sleep deprivation on signaling in a eusocial animal.

220 One of the major effects of sleep deprivation on the brain is to produce memory defi

221 Therefore, we explored the influence of sleep deprivation on the human brain using two different

222 ise time-of-day variation and the effects of sleep deprivation on urinary metabolite profiles.

223 hanges in cognitive performance during acute sleep deprivation (one prolonged wake episode), chronic

224 odents, behavioral arousal induced either by sleep deprivation or caffeine during the sleeping period

225 ntions with a rapid onset of action--such as sleep deprivation or intravenous drugs (e.g., ketamine o

226 ration of circulating TNF-alpha after either sleep deprivation or sleep fragmentation (SF) appear to

227 iants of the foraging gene (for) with either sleep deprivation or starvation.

228 Sleep deprivation, or prolonged wakefulness, interferes

229 any patients with major depressive disorder, sleep deprivation, or wake therapy, induces an immediate

230 d by tissue hypoxia, catecholamine infusion, sleep deprivation, pain, anxiety, and/or excess noise.

231 erving spontaneous eyelid closures following sleep deprivation permits nonintrusive arousal monitorin

232 Chronic sleep deprivation perturbs the circadian clock and incre

233 in hippocampal neurons during the course of sleep deprivation prevented these memory consolidation d

234 er transiently increasing cAMP levels during sleep deprivation prevents memory consolidation deficits

235 nal time at which the animal was sacrificed; sleep deprivation prior to sacrifice greatly increased b

236 We find that acute sleep deprivation profoundly suppresses aggressive behav

237 ind with both measures that LRTCs decline as sleep deprivation progresses.

238 eding in mammals are tightly interconnected: sleep deprivation promotes feeding, whereas starvation s

239 of TMS-evoked responses recorded over a 29 h sleep deprivation protocol conducted in young and health

240 d body temperature variations during two 72h sleep deprivation protocols are reproduced by the model.

241 ifferential vulnerability to chronic partial sleep deprivation (PSD), a condition distinct from total

242 We had shown that sleep deprivation reduced dopamine D2/D3 receptor availa

243 Our findings show that sleep deprivation reduced functional connectivity betwee

244 Here we show in mice that donor sleep deprivation reduces the ability of its haematopoie

245 imates and rodents it was found that, during sleep deprivation, regional 'sleep-like' slow and theta

246 rapid eye movement (REM) sleep following REM sleep deprivation remain unknown.

247 nd sex in the multivariate regression model, sleep deprivation remained an independent predictor for

248 ein, we argue that experimentally controlled sleep deprivation represents a translational model syste

249 Recovery of sleep after sleep deprivation restored the reconstitution potential

250 g behavioral impairments under conditions of sleep deprivation/restriction.

251 Sleep deprivation resulted in a higher A1AR availability

252 As a consequence, sleep deprivation resulted in similar processing of neut

253 However, only sleep deprivation resulting from activation of cholinerg

254 In contrast, sleep deprivation resulting from activation of octopamin

255 Sleep deprivation results in a sleep rebound.

256 remained constant throughout a 6 h period of sleep deprivation, returning to baseline levels immediat

257 Drug administration was preceded by 6 h of sleep deprivation (SD) ('high sleep pressure') or undist

258 x after 6-8 h of sleep, spontaneous wake, or sleep deprivation (SD) and after chronic ( approximately

259 Sleep deprivation (SD) can have a negative impact on cog

260 Acute sleep deprivation (SD) can trigger or exacerbate psychos

261 mpaired memory consolidation associated with sleep deprivation (SD) could be compensated by increased

262 A single night of sleep deprivation (SD) evoked a strategy shift during ri

263 Sleep deprivation (SD) has detrimental effects on cognit

264 Consequently, sleep deprivation (SD) is associated with adverse conseq

265 Sleep deprivation (SD) might be such a model as it has p

266 Yet the effect of sleep deprivation (SD) on decision making and performanc

267 ersely, changes in behavioral state, such as sleep deprivation (SD) or arousal, can phase shift the c

268 ssant strategies, low-dose ketamine (KT) and sleep deprivation (SD) therapies, dramatically reduce de

269 ressant interventions, low-dose ketamine and sleep deprivation (SD) therapy, act within hours to robu

270 that whereas Hcrt(ko/ko) mice respond to 6-h sleep deprivation (SD) with a slow-wave sleep (SWS) EEG

271 Although different studies associated sleep deprivation (SD) with systemic inflammatory change

272 cellular source of iNOS-generated NO during sleep deprivation (SD), we used intracerebroventricular

273 e resistant to the antidepressant effects of sleep deprivation (SD).

274 ers at baseline and during and after 12 h of sleep deprivation (SD).

275 examine the electrophysiological effects of sleep deprivation (SD).

276 ice during undisturbed 24 h, and after a 6-h sleep deprivation (SD).

277 s at understanding the mechanisms underlying sleep deprivation (SDe)-induced enhancement of reward se

278 Here we report that sleep deprivation significantly decreases activity in ap

279 Moreover, sleep deprivation significantly degrades the normally re

280 cognitive deficits, that typically accompany sleep deprivation, such as the loss of mental flexibilit

281 of D2/D3 receptors in ventral striatum with sleep deprivation that may contribute to the associated

282 -gain promoting high-calorie foods following sleep deprivation, the extent of which is predicted by t

283 as some sleep pressure correlates respond to sleep deprivation, the strongest electroencephalogram (E

284 s with the chronotherapeutic intervention of sleep deprivation therapy (SDT).

285 The example of sleep deprivation thus demonstrates the ability of physi

286 ompared participants with one night of total sleep deprivation to participants with a night of regula

287 Total sleep deprivation (TSD) exerts strong modulatory effects

288 table with repeated exposures to acute total sleep deprivation (TSD) within a short-time interval (we

289 and neurocognitive performance during total sleep deprivation (TSD).

290 Here, we subjected C57BL/6 mice to 6 h of sleep deprivation using two different methods: gentle ha

291 ne by blocking dopamine transporters) during sleep deprivation versus rested sleep, with the assumpti

292 Sleep deprivation (wake therapy) provides rapid clinical

293 Recovery from sleep deprivation was associated with a decrease in A1AR

294 In addition, the homeostatic response to sleep deprivation was greatly attenuated with disease pr

295 nosine release and basal tone resulting from sleep deprivation was reversed by the inducible nitric o

296 participants who underwent a night of total sleep deprivation were replicated in an independent data

297 This becomes particularly evident during sleep deprivation, when the interplay between these stat

298 igh-density EEG after normal sleep and after sleep deprivation while participants observed a Necker c

299 sion is selectively weakened following acute sleep deprivation, whose restoration normalizes reward s

300 We conducted a 2 (sleep deprivation: yes vs. no) x2 (competency of advisor