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1 , implementing nighttime routines to address sleep disturbances).
2 able to a positive energy balance because of sleep disturbance.
3 life, an association not explained by VMS or sleep disturbance.
4 ain, poor nutrition, sensory impairment, and sleep disturbance.
5 oth the subjective and objective measures of sleep disturbance.
6               The PPND kindred showed severe sleep disturbance.
7          None had a history of depression or sleep disturbance.
8 nce of a prior depressive episode along with sleep disturbance.
9 stem-mediated symptoms including fatigue and sleep disturbance.
10 llowed by fatigue, chest pain, headache, and sleep disturbance.
11  motivated behavior, psychosis, anxiety, and sleep disturbance.
12 en implicated in narcolepsy, correlated with sleep disturbance.
13  disorder exhibited a clinically significant sleep disturbance.
14 associated with behavioral abnormalities and sleep disturbance.
15 he strongest relationship with the degree of sleep disturbance.
16 antly higher levels of depression, pain, and sleep disturbance.
17 ological states, often in association with a sleep disturbance.
18 abuse in accounting for different domains of sleep disturbance.
19 nic disease may underlie the pathogenesis of sleep disturbance.
20 er such association is related to fatigue or sleep disturbance.
21 mor and symptoms of fatigue, depression, and sleep disturbance.
22  a questionnaire including information about sleep disturbances.
23 attention deficits, affective disorders, and sleep disturbances.
24 retardation, loss of motor coordination, and sleep disturbances.
25 s, daytime sleepiness, and elevated risk for sleep disturbances.
26 nt treatment research has targeted these two sleep disturbances.
27 e generation of BSAEP and VEP, as well as in sleep disturbances.
28  on the VAS for pain, global well-being, and sleep disturbances.
29 e disease accompanied by atopy, fatigue, and sleep disturbances.
30 al disorder whose non-motor symptoms include sleep disturbances.
31  (ISI), a validated instrument for assessing sleep disturbances.
32 ) have impaired receptor function and showed sleep disturbances.
33  with normal sleep-wake regulation and cause sleep disturbances.
34  earliest abnormalities in premanifest HD is sleep disturbances.
35 accompanied by fatigue, memory problems, and sleep disturbances.
36 to new treatment strategies for a variety of sleep disturbances.
37 fatigue or somnolence (35 patients [41.1%]), sleep disturbance (12 [14.1%]), and urinary symptoms (8
38  research and has been regarded as a typical sleep disturbance [2-4].
39 depression, 40.7% anxiety, 15.0% pain, 36.7% sleep disturbance, 33.3% morning fatigue, and 30.0% even
40 nth before AMI were unusual fatigue (70.7%), sleep disturbance (47.8%), and shortness of breath (42.1
41 n, 51.4) and cervical cancer (anxiety, 53.2; sleep disturbance, 53.4).
42 t symptoms/signs were radicular pain (100%), sleep disturbances (75.3%), erythema migrans (59.7%), he
43 l disabilities, behavioral abnormalities and sleep disturbances, a majority of children with SMS also
44 ncluded positive symptoms, bizarre thinking, sleep disturbances, a schizotypal disorder, level of fun
45  This study is the first to demonstrate that sleep disturbance acts as an independent risk factor for
46 ple mechanisms have been identified by which sleep disturbances adversely affect cardiovascular struc
47 ext day in healthy subjects, suggesting that sleep disturbances alone may worsen pain, and experiment
48 nd insomnia and to identify risk factors for sleep disturbance among patients with asthma, in a large
49 lth workers may consider routinely assessing sleep disturbances among HIV-infected patients, especial
50                                        While sleep disturbance and circadian dysregulation are critic
51               Risk is highest for those with sleep disturbance and co-occurring anxiety disorders or
52                        Treatment options for sleep disturbance and future directions for research are
53 e and autonomic neural underpinnings linking sleep disturbance and immunity and the reciprocal links
54 l melatonin were found to be associated with sleep disturbance and increased disease severity in chil
55                                              Sleep disturbance and long sleep duration, but not short
56 e events such as weight gain, skin thinning, sleep disturbance and neuropsychiatric disorders may occ
57                                              Sleep disturbance and other symptoms that are diagnostic
58      Eczema is associated with high rates of sleep disturbance and quality-of-life impairment.
59 iver exhaustion is a frequent consequence of sleep disturbance and rest-activity rhythm disruption th
60 A users may be related, at least in part, to sleep disturbance and suggest that cognitive deficits in
61 r and their FCs experience similar levels of sleep disturbance and that both groups could benefit fro
62 ied the association between adult eczema and sleep disturbance and their impact on overall health and
63 ogic study has examined the relation between sleep disturbance and thyroid cancer risk.
64 primary research articles that characterized sleep disturbance and/or sleep duration or performed exp
65 regiver stress can lead to psychological and sleep disturbances and changes in caregivers' physical h
66 inical studies suggest a correlation between sleep disturbances and cognitive dysfunction in patients
67                                              Sleep disturbances and cognitive impairment are common i
68 rapies to treat and potentially prevent both sleep disturbances and cognitive impairment.
69 Parkinson's disease (PD) display significant sleep disturbances and daytime sleepiness.
70 ated VS activity increases, the link between sleep disturbances and depression decreases.
71     Most research on the association between sleep disturbances and depression has looked at cross-se
72 S activity increased the association between sleep disturbances and depressive symptoms decreased.
73  These children also displayed more frequent sleep disturbances and episodes of aggression.
74  major depression and exhibited appetite and sleep disturbances and fatigue (somatic depression) and
75 indecisiveness and less likely to experience sleep disturbances and feelings of worthlessness or exce
76 ent fish consumption is associated with less sleep disturbances and higher IQ scores in schoolchildre
77             However, it is not known whether sleep disturbances and metabolic abnormalities underlyin
78 robust evidence for the relationship between sleep disturbances and psychiatric outcomes and symptoms
79 hronic inflammatory disorder associated with sleep disturbances and quality-of-life impairment.
80 tudies have examined the association between sleep disturbances and semen quality.
81 the first study to find associations between sleep disturbances and semen quality.
82 ssion spectrum, psychosis spectrum, anxiety, sleep disturbances and stress) across community-dwelling
83  to study the relation between self-reported sleep disturbances and subsequent clinical depression an
84                      The interaction between sleep disturbances and VS activity was robust to the inc
85 terest-muscle-related, erectile dysfunction, sleep disturbance, and cognitive impairment-and analysed
86           Results also suggest that fatigue, sleep disturbance, and depression may stem from distinct
87 ties, including self-injurious behaviors and sleep disturbance, and distinct craniofacial and skeleta
88 e and severity of depression, anxiety, pain, sleep disturbance, and fatigue; determine the relationsh
89 onding to manic activation, depressed state, sleep disturbance, and irritability/paranoia.
90 igher levels of depression, morning fatigue, sleep disturbance, and lower levels of evening fatigue r
91 essure (BP), including chronic inflammation, sleep disturbance, and mental health comorbidity.
92 ort the efficacy of prazosin for nightmares, sleep disturbance, and other PTSD symptoms.
93 o evaluate prazosin efficacy for nightmares, sleep disturbance, and overall posttraumatic stress diso
94 bivalence over expressing negative emotions, sleep disturbance, and poorer social functioning.
95 es for pain, functional disability, fatigue, sleep disturbance, and psychological status, and these v
96 er adjustment for delusions, hallucinations, sleep disturbance, and severity of cognitive impairment.
97 ression, mania or agitation, hallucinations, sleep disturbance, and suicidal ideation.
98            Headache, gastrointestinal upset, sleep disturbance, and sympathetic nervous system arousa
99 lings of threat, restlessness, irritability, sleep disturbance, and tension, and symptoms such as pal
100 , asthma), major quality-of-life impairment, sleep disturbance, and the use of potent topical and som
101 sion, depression recurrence was predicted by sleep disturbance, and this association was independent
102    Major exposures were depressive, anxiety, sleep disturbance, and vasomotor symptoms and menopause
103  The authors found that depressive, anxiety, sleep disturbance, and vasomotor symptoms did not accoun
104 followed by baseline anxiety level, baseline sleep disturbance, and--for a minority of patients--the
105 used and identified five classes of fatigue, sleep disturbances, and allergic disorders.
106 an association between short sleep duration, sleep disturbances, and circadian desynchronisation of s
107 lterations that include depression, fatigue, sleep disturbances, and cognitive dysfunction.
108 more than just pain; depression and anxiety, sleep disturbances, and decision-making abnormalities al
109 f bladder disorders, including hyperarousal, sleep disturbances, and disruption of sensorimotor integ
110 g tasks reminiscent of the deceased, unusual sleep disturbances, and maladaptive levels of loss of in
111           The relationship among nightmares, sleep disturbances, and PTSD symptoms is discussed.
112 SD have yielded mixed findings regarding REM sleep disturbances, and they generally suggest modest an
113 r patients age 65 to 84 years reported lower sleep disturbance, anxiety, and depression, and better c
114 , but still positive, therapeutic benefit on sleep disturbance, anxiety, appetite loss, physical symp
115  measures of pain, global severity, fatigue, sleep disturbance, anxiety, depression, and health statu
116 res, delayed language and motor development, sleep disturbances, anxiety-like behaviour, severe cogni
117                                              Sleep disturbance appears to be a less important predict
118 ss, headache, cognitive processing speed and sleep disturbance are associated with tinnitus.
119                     Fatigue, depression, and sleep disturbance are common adverse effects of cancer t
120 e risk for depression.SIGNIFICANCE STATEMENT Sleep disturbances are a common risk factor for depressi
121 ms such as repetitive speech, wandering, and sleep disturbances are a core clinical feature of Alzhei
122            Prompt diagnosis and treatment of sleep disturbances are advocated and may improve quality
123                                              Sleep disturbances are among the most prominent correlat
124                    We propose that circadian sleep disturbances are an important pathological feature
125                                              Sleep disturbances are associated with hormonal imbalanc
126                                              Sleep disturbances are associated with poor health outco
127                                              Sleep disturbances are increasingly recognized as a comm
128                                              Sleep disturbances are known to occur in both schizophre
129                                              Sleep disturbances are recognized as a common nonmotor c
130                                              Sleep disturbances are reportedly common among persons i
131 The hypothesis that rapid eye movement (REM) sleep disturbances are the hallmark of posttraumatic str
132 leep, abnormal sleep-wake transition and non-sleep disturbances as well as lab tests in Chinese fatal
133 ry treatment with corticosteroids, pain, and sleep disturbance, as well as psychosocial factors inclu
134 ndings may also be relevant to understanding sleep disturbances associated with psychopathology.
135                                      Chronic sleep disturbances, associated with cardiometabolic dise
136 nd 24 months, by loss of sexual interest and sleep disturbance at 6 months, and by vaginal dryness up
137 e measures of the occurrence and severity of sleep disturbance at the initiation of RT.
138 n was used to assess the association between sleep disturbance because of worry and the risk for inci
139                                              Sleep disturbance because of worry predicted the develop
140                      Survey respondents with sleep disturbances because of worry at the time of the b
141                                              Sleep disturbances because of worry may increase risk fo
142 roblems among individuals with self-reported sleep disturbances because of worry.
143                                      Despite sleep disturbance being a common complaint in individual
144 currence of clinically significant levels of sleep disturbance between patients and their FCs that ra
145  and resulted in a small benefit in terms of sleep disturbance but no benefit in terms of the other q
146                                              Sleep disturbance, but not VMS, was independently associ
147 tion to routine and systematic assessment of sleep disturbance by oncology clinicians, interventions
148 eep measures are needed to determine whether sleep disturbance causes or accelerates Alzheimer diseas
149                                              Sleep disturbances characterize depression and may refle
150 e in women when vasomotor symptoms (VMS) and sleep disturbance commonly disrupt QOL.
151 up (26%) (P =.047), as well as a decrease in sleep disturbance compared with the placebo group on the
152                                              Sleep disturbance correlated positively with metabolism
153 elopmental delays, behavioral abnormalities, sleep disturbance, craniofacial and skeletal abnormaliti
154 l sequelae of breast cancer, namely fatigue, sleep disturbance, depression, and cognitive impairment.
155              Older adults have high rates of sleep disturbance, die by suicide at disproportionately
156 se events (self-reported breathing problems, sleep disturbances, drowsiness or tiredness, nausea, swe
157              Nonocular risk factors included sleep disturbances (eg, sleep apnea and insomnia), menta
158            We propose that psychosis and the sleep disturbances experienced by Parkinsonian patients
159 chronic pain commonly experience depression, sleep disturbance, fatigue, and decreased overall physic
160 aracterized by chronic musculoskeletal pain, sleep disturbance, fatigue, and difficulty with daily fu
161 gy mechanisms underscore the implications of sleep disturbance for inflammatory disease risk, and pro
162 oms (fatigue, shortness of breath, headache, sleep disturbance, forgetfulness, and impaired concentra
163 a, loss of appetite, depression, anxiety, or sleep disturbance) >/= 4 of 10 on the Edmonton Symptom A
164 rch over the past decade has documented that sleep disturbance has a powerful influence on the risk o
165                                              Sleep disturbance has been found to be associated with n
166                                              Sleep disturbances have been shown to cause headaches in
167  depression and emotional lability, fatigue, sleep disturbance, head drop, prevention of deep venous
168 kinson's disease, global polyuria, insomnia, sleep disturbances, heart failure, anxiety, and depressi
169 o probe biological phenotypes of PTSD (e.g., sleep disturbances, hippocampal and fear-circuit dysfunc
170 d the prevalence and factors associated with sleep disturbance in a large cohort of HIV-infected pati
171 public health problem and is the most common sleep disturbance in both adults and children.
172                                          The sleep disturbance in cirrhosis was not associated with c
173 occurrence rates for and severity ratings of sleep disturbance in patient-family caregiver (FC) dyads
174 er, appropriate evaluation and management of sleep disturbance in patients with bipolar illness is fu
175                                              Sleep disturbance in patients with epilepsy is frequentl
176 study aims to characterize the nature of the sleep disturbance in PPND and compare these findings to
177       Tests of mediation implicated baseline sleep disturbance in the cognitive decline seen during s
178 polysomnography, we found that the temporary sleep disturbance in the first sleep experimental sessio
179 l and longitudinal analyses, as well as with sleep disturbances in cross-sectional analyses.
180                                              Sleep disturbances in Huntington's disease may be delete
181  promote increased sleep drive may alleviate sleep disturbances in individuals with AS.
182 ssociations were observed between reports of sleep disturbances in medical school and psychiatric dis
183                                              Sleep disturbances in neurological disorders have a deva
184 ty and a potential mechanism contributing to sleep disturbances in Parkinson's disease.
185 s among rhythm disturbances, sundowning, and sleep disturbances in patients with Alzheimer's disease.
186 o objective evidence for clinically relevant sleep disturbances in PTSD.
187      We therefore evaluated polysomnographic sleep disturbances in PTSD.
188                                   Persistent sleep disturbances in remitted patients may have ominous
189 perceived effect of environmental stimuli on sleep disturbances in the ICU.
190  duration, motor severity and complications, sleep disturbances, in particular excessive daytime somn
191 ociated symptom (pains, dizziness, headache, sleep disturbance, inability to relax, irritability) tha
192                                              Sleep disturbances including insomnia independently cont
193       Suicidal psychiatric patients had more sleep disturbances including insomnia, hypersomnia, or n
194                Depression is associated with sleep disturbances, including alterations in non-rapid e
195                Depression is associated with sleep disturbances, including alterations in rapid eye m
196 inical manifestations in all 5 patients were sleep disturbances, including insomnia, laryngeal strido
197 zard ratios and 95% confidence intervals for sleep disturbance (insomnia and sleep duration) and risk
198                                              Sleep disturbances interact with common mental disorders
199                                              Sleep disturbance is a classic sign of hepatic encephalo
200                                              Sleep disturbance is associated with activation of syste
201                                              Sleep disturbance is associated with inflammatory diseas
202                                              Sleep disturbance is common in bipolar disorder.
203                                              Sleep disturbance is common in children with atopic derm
204                             In conclusion, a sleep disturbance is frequent in cirrhotic patients with
205                                Prevalence of sleep disturbance is high in this large Chinese cohort.
206                                              Sleep disturbance is important because it impairs qualit
207 transfusions, gastrointestinal symptoms, and sleep disturbance items, as well as with low serum hemog
208              For the depression-alone group, sleep disturbance may partially explain the negative imp
209                      Similarly, treatment of sleep disturbance may serve as both a target of treatmen
210  spindle, and ripple events, indicating that sleep disturbances may be associated with state-dependen
211 n patients with Parkinson's disease but that sleep disturbances may first need to be corrected.
212 operative ileus, anxiety/mood disorders, and sleep disturbance) met all inclusion criteria.
213               The nightmare is the domain of sleep disturbance most related to exposure to war zone t
214                                              Sleep disturbances negatively impact numerous functions
215                      On standard measures of sleep disturbance, no differences were detected between
216                                      Neither sleep disturbances nor sleep duration was associated wit
217  insight into epigenetic-based regulation of sleep disturbances observed in neurodegenerative disease
218    Paradoxically, headache, facial pain, and sleep disturbance occurred significantly more frequently
219                                              Sleep disturbance occurs in most patients with delusions
220 ted problem, relative to those without these sleep disturbances (odds ratio=2.32, 95% confidence inte
221 ted syndromes are depression, psychosis, and sleep disturbance of Alzheimer's disease.
222                           The characteristic sleep disturbances of depression may reflect this dysreg
223 ted VS activity would moderate the effect of sleep disturbances on depression in a large cohort of yo
224 e increasingly points to the large impact of sleep disturbances on public health.
225 ther symptoms, for symptoms such as profound sleep disturbance or psychotic symptoms may dominate the
226 children (OR = 5.80; 95% CI, 1.30 to 25.82), sleep disturbances (OR = 6.15; 95% CI, 2.33 to 16.22), p
227 es would also be helpful to identify whether sleep disturbances (or improvement of sleep quality) can
228 cortisol were not related to medication use, sleep disturbance, or disability levels.
229 rted experiencing pain, discomfort, anxiety, sleep disturbance, or unsatisfied hunger or thirst that
230                                     In acute sleep disturbance, oral administration of glycine-induce
231  the development of nonspecific symptoms and sleep disturbances over time.
232 chophysiological insomnia) or may complicate sleep disturbance owing to other causes.
233 ymptom scores (p = 0.388, 0.179, and 0.215), sleep disturbance (p = 0.101), morning or afternoon peak
234  CPM levels might be attributed, in part, to sleep disturbance (P=0.04).
235 atigue were also associated with depression: sleep disturbances, pain, obesity, and cognitive impairm
236 rom observational studies support a role for sleep disturbances (particularly for sleep duration, sle
237  interference, fatigue, anxiety, depression, sleep disturbance, physical function, ability to partici
238 ot clinically meaningful benefit in terms of sleep disturbance, physical functioning, and bodily pain
239 by examining the inter-relationships between sleep disturbance, physical symptoms, emotional problems
240 ent study sought to test the hypothesis that sleep disturbance plays a role in cognitive deficits in
241 with prior depression, it is unclear whether sleep disturbance predicts depression recurrence indepen
242 alyses controlling for age, sex, depression, sleep disturbance, recent traumatic life events, and pai
243                                         Mild sleep disturbance reduced sleep and increased c-fos expr
244                                   The type 1 sleep disturbances (reduced rapid eye movement latency,
245                                              Sleep disturbance remains an independent correlate of lo
246 were two-fold: 1) to describe the pattern of sleep disturbances reported in a large sample of childre
247 tributing to the increased susceptibility to sleep disturbances reported in women.
248 ics were used to characterize the pattern of sleep disturbances reported, while structural equation m
249                                              Sleep disturbances represent one risk factor for depress
250 h Sleep Quality Index (PSQI) and the General Sleep Disturbance Scale (GSDS) and wore wrist actigraphs
251                     Men with a high level of sleep disturbance (score >50) had a 29% (95% confidence
252                                              Sleep disturbances showed an inverse U-shaped associatio
253 men (2008-2011), Jensen et al. reported that sleep disturbances showed inverse U-shaped associations
254 t several hours later generates a pattern of sleep disturbances similar to that observed in stress-in
255 s a numerically greater incidence of nausea, sleep disturbance, skin reactions, constipation, and dep
256      Here, we assess global evidence linking sleep disturbance, sleep duration, and inflammation in a
257 unity, with consideration of the dynamics of sleep disturbance, sleep restriction, and insomnia on (a
258 ssion and exhibited fatigue and appetite and sleep disturbance ("somatic depression") and those who m
259  significant interactions between eczema and sleep disturbances such that eczema associated with fati
260  in the LH and ameliorated the ppDIO-induced sleep disturbances, suggesting the therapeutic potential
261 ia, problems with gastrointestinal motility, sleep disturbances, sympathetic denervation, anxiety, an
262 esia in intensive care units associated with sleep disturbances, tachycardia, pulmonary complications
263 essive phase of bipolar illness is marked by sleep disturbance that may be amenable to somatic therap
264 the states of sleep is responsible for those sleep disturbances that arise as a consequence of hypoxi
265           However, little is known about the sleep disturbances that occur in adult eczema.
266 rt neurons is likely to produce the multiple sleep disturbances that occur in narcolepsy.
267  Finally, we review the latest literature on sleep disturbances that persist or develop after critica
268 dividuals with Angelman syndrome (AS) suffer sleep disturbances that severely impair quality of life.
269                 After adjustment for VMS and sleep disturbance, the comorbid group continued to have
270 h levels of fatigue, poor concentration, and sleep disturbance; the latter was more marked in women (
271 but no significant differences were found in sleep disturbance, Tinel sign, and median nerve motor an
272 ch include discussion of the contribution of sleep disturbance to depression and especially inflammat
273  Other common symptoms such as mood changes, sleep disturbances, urinary incontinence, cognitive chan
274 after one year (the mean benefit in terms of sleep disturbance was 0.4 point on a 20-point scale, in
275                                              Sleep disturbance was associated with higher levels of C
276                       The rate of reports of sleep disturbance was significantly lower among particip
277 ability (anger), concentration deficits, and sleep disturbance were found.
278 l; 6 = very much), nonspecific symptoms, and sleep disturbances were assessed by questionnaire.
279                                              Sleep disturbances were assessed on the basis of a modif
280                                              Sleep disturbances were associated with several factors
281                                              Sleep disturbances were observed in 43.1% of patients.
282 lating evidence indicates that circadian and sleep disturbances, which have long been considered symp
283 ions in adenoid size and respiratory-related sleep disturbances, which were absent in 16 children wit
284                         FFI is manifested by sleep disturbances with insomnia, autonomic disorders an
285 uces opioid consumption, pain, vomiting, and sleep disturbance, with improved knee range of motion af
286      As many as 10% of humans suffer chronic sleep disturbances, yet the genetic mechanisms that regu

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