ライフサイエンスコーパス: sleep fragmentation

1 ty (hypoxemia, respiratory disturbances, and sleep fragmentation).

2 ith hypoxemia, respiratory disturbances, and sleep fragmentation.

3 e-movement (REM) sleep, as well as increased sleep fragmentation.

4 long with changes in cerebral blood flow and sleep fragmentation.

5 sed night sleep and day activity and reduced sleep fragmentation.

6 individual, and related this to ante-mortem sleep fragmentation.

7 sive function, and appears to correlate with sleep fragmentation.

8 nd separate it from nonrespiratory causes of sleep fragmentation.

9 central apneas, adding dead space decreased sleep fragmentation: 44 +/- 6 versus 83 +/- 12 arousals

10 akefulness, narcoleptic mammals also display sleep fragmentation, a less understood phenotype recapit

11 cases showed reduction in total sleep time, sleep fragmentation, abnormal short non-rapid eye moveme

12 of CP-AMPARs in the NAc, whereas increasing sleep fragmentation accelerated NAc CP-AMPAR accumulatio

13 In contrast, experimentally increasing sleep fragmentation after cocaine self-administration ex

14 ent hypoxemia, hemodynamic fluctuations, and sleep fragmentation, all of which could damage cerebral

15 to both increased daytime blood pressure and sleep fragmentation, all participants with an apnea-hypo

16 comprised sleep episodes during daytime and sleep fragmentation and a reduction of sleep efficiency

17 a valuable model for studying age-associated sleep fragmentation and breakdown of rhythm strength, an

18 ection of respiratory disturbance may reduce sleep fragmentation and excessive daytime sleepiness.

19 f obstruction of the upper airway leading to sleep fragmentation and intermittent hypoxia during slee

20 t is not responsible for the majority of the sleep fragmentation and may therefore not be as disrupti

21 SD mPrP(0/0) mice showed a larger degree of sleep fragmentation and of latency to enter rapid eye mo

22 ar target for interventions that may prevent sleep fragmentation and the attendant cardiovascular and

23 Measures of hypoxia, sleep fragmentation, and sleep duration were investigate

24 sturbances (particularly for sleep duration, sleep fragmentation, and sleep-disordered breathing) in

25 of literature suggesting that sleep loss and sleep fragmentation are associated with blunted hypercap

26 apnea, the relative roles of hypoxia versus sleep fragmentation are difficult to separate in apneic

27 s suggest that AHI, nocturnal hypoxemia, and sleep fragmentation are independent determinants of hype

28 Measures of sleep fragmentation (arousal index and wake after sleep

29 Sleep fragmentation, as assessed by the distribution of

30 Such sleep fragmentation, as well as abnormalities evident in

31 In adjusted analyses, greater sleep fragmentation associated with increased ESRD risk

32 Sleep fragmentation caused hyperalgesia in volunteers, w

33 h the effects of intermittent hypoxaemia and sleep fragmentation, could contribute independently to t

34 characterized by prolonged sleep latencies, sleep fragmentation, decreased sleep efficiency, frequen

35 pressure score (SPS), a surrogate measure of sleep fragmentation emerged (p = 0.02, r = -0.51) emerge

36 We found that sleep fragmentation enhanced tumor size and weight compa

37 fulness drive can lead to central apneas and sleep fragmentation, especially in patients with heart f

38 for pharmacological treatment of age-related sleep fragmentation in humans.

39 termediate nucleus neurons is accompanied by sleep fragmentation in older adults with and without Alz

40 We demonstrate that sleep loss, but not sleep fragmentation, in healthy mice increases sensitivi

41 age 1 sleep divided by the total sleep time (sleep fragmentation index: SFI).

42 n-based study, we tested the hypothesis that sleep fragmentation is associated with elevated awake bl

43 st that sleep difficulties, specifically REM sleep fragmentation, may play a mechanistic role in post

44 Sleep fragmentation, measured as the number of arousals

45 similar between ventilator groups, including sleep fragmentation (number of arousals and awakenings/h

46 -reported mean (SD) sleep metrics, including sleep fragmentation (number of overnight awakenings, 1.5

47 geing in diverse organisms, could rescue the sleep fragmentation of ageing Drosophila.

48 esign, we compared mice that were exposed to sleep fragmentation one week before engraftment of synge

49 es 1 and 2) without significant increases in sleep fragmentation or decreases in rapid eye movement (

50 odone/ L-tryptophan dose-dependently reduced sleep fragmentation, p = 0.03, increased sleep efficienc

51 Sleep fragmentation, particularly reduced and interrupte

52 r sleep duration (per hour less) and greater sleep fragmentation (per 1% more) each associated with g

53 ts, the more aggressive features produced by sleep fragmentation persisted.

54 Sleep fragmentation predicted approximately twice the va

55 this study, we examined the hypothesis that sleep fragmentation promotes tumor growth and progressio

56 th delayed sleep onset latency and increased sleep fragmentation (reduced sleep state percentages, nu

57 leep time, which is accompanied by increased sleep fragmentation resembling chronic insomnia.

58 TNF-alpha after either sleep deprivation or sleep fragmentation (SF) appear to underlie excessive da

59 Chronic sleep fragmentation (SF) commonly occurs in human popula

60 Sleep fragmentation (SF) is a common condition among pre

61 Sleep fragmentation (SF) is a highly prevalent condition

62 duced (1) sleep-induced hypoxia (SIH) or (2) sleep fragmentation (SF) without hypoxia for 5 days (12-

63 Sleep fragmentation (SF), a primary feature of obstructi

64 ated macrophages (TAM) were more numerous in sleep fragmentation tumors, where they were distributed

65 Increased invasiveness was apparent in sleep fragmentation tumors, which penetrated the tumor c

66 lept an average of 6.5 hours per night; mean sleep fragmentation was 21%.

67 with right amygdala volume, and more severe sleep fragmentation was associated with increased thickn

68 Sleep fragmentation was defined as the total number of a

69 , these more aggressive features produced by sleep fragmentation were abolished completely in TLR4(-/