ライフサイエンスコーパス: slowing

1 pair but also by preventing replication fork slowing.

2 ionships between CRP and anhedonia and motor slowing.

3 negativity (ERN) and consecutive behavioural slowing.

4 These effects were absent on post-conflict slowing.

5 rature dependence characteristic of critical slowing.

6 ing errors, a phenomenon known as post-error slowing.

7 o expend effort for rewards; and psychomotor slowing.

8 amplitude did not correlate with post-error slowing across participants.

9 s, but the impact of this activity-dependent slowing (ADS) is unknown.

10 C fibers display activity-dependent slowing (ADS), whereby repetitive stimulation (>/=1 Hz)

11 d TGF-beta1 signaling axis holds promise for slowing age- and disease-related degeneration of NMJs.

12 t provide evidence of a beneficial effect on slowing AMD progression.

13 hibit behavioral modifications with ideation slowing and aggressiveness, sometimes contrasting with m

14 ng, yet a direct relationship between neural slowing and brain atrophy is yet to be established in he

15 ted perceptual events-and they lead to motor slowing and cognitive distraction.

16 cient (Mpo(-/-)) mice showed less pronounced slowing and decreased heterogeneity of electric conducti

17 oop accumulation results in replication fork slowing and DNA damage.

18 Significant heart rate slowing and frequent sinus pauses are observed in iNICD

19 ti-ion channel block, with significant sinus slowing and increased PR, QRS, QT, and QTc intervals, as

20 c sodium channelopathy, including conduction slowing and increased susceptibility to ventricular arrh

21 ile polar sterols produced a more pronounced slowing and inhibition of fusion.

22 High doses (40-55 Gy) caused slowing and interruption of cardiac impulse propagation.

23 suggesting fork remodeling as a global fork slowing and protection mechanism.

24 ble to a combination of DNA replication fork slowing and reduced replication origin firing.

25 Motor slowing appears in preclinical Alzheimer disease (AD), p

26 ese structures, which upend traditional wave-slowing approaches based on resonances or on periodic co

27 the UV hypersensitivity and replication fork slowing are reversed by expression of H3.3 and require t

28 outflow and by measuring activity-dependent slowing at 2 Hz stimulation.

29 h task to differentiate potential sources of slowing at separable levels of processing: the posterior

30 choking, vertical supranuclear gaze palsy or slowing, balance difficulties with falls and urinary inc

31 amics of coupling between ERN and post-error slowing between men and women is comparable.

32 o increase apparent viscosity significantly, slowing blood flow velocity at arterial oxygen tension e

33 importance of vitamin B12 supplementation on slowing brain aging in older adults.

34 Females showed more post-error slowing, but both samples did not differ in regard to re

35 hydration shell remains remarkably dynamic, slowing by less than a factor of 2, if at all, compared

36 g promotes adhesion to HA by both physically slowing cells and enabling them to position proximal to

37 on by increasing single-channel conductance, slowing channel gating, increasing calcium permeability,

38 itigation policies specifically derived from slowing climate change.

39 veness of physical activity interventions in slowing cognitive decline and delaying the onset of cogn

40 pid initial rates of H2O2 disproportionation slowing concomitantly with the accumulation of ferryl-li

41 The faster phase of voltage-sensor return slowing correlated with the kinetics of pore opening.

42 alter voltage sensor-pore coupling, thereby slowing current deactivation.

43 C6) activity, have hence proven effective in slowing cyst progression.

44 ing the voltage dependence of activation and slowing deactivation, similar to perfusion of isoprotere

45 ementia risk by improving memory function or slowing decline.

46 income had the largest estimated benefit for slowing declines (for 10-year memory change, beta = 0.35

47 by attenuating microglial activation and by slowing degradation of neuronal cell bodies and termini

48 ortactin cooperate to stabilize filaments by slowing depolymerization.

49 In compliment, we show that slowing detachment from this vulnerable state by strengt

50 Slowing diffusion with dextran prolonged the rise and re

51 increasing rate of antibiotic resistance and slowing discovery of novel antibiotic treatments present

52 ursodeoxycholic acid that are aimed at both slowing disease course and improving quality of life.

53 This may be important in slowing disease progression and provides insight into th

54 E supports the continued efficacy of A1PI in slowing disease progression during 4 years of treatment.

55 E supports the continued efficacy of A1PI in slowing disease progression during 4 years of treatment.

56 y may be an effective therapeutic target for slowing disease progression.

57 plication stress, including replication fork slowing, DNA damage and senescence.

58 For instance, critical slowing down (declining rate of recovery from small pert

59 on points suggests that symptoms of critical slowing down (i.e., the slowed recovery of the system fr

60 ational and experimental support of critical slowing down along natural stress gradients in tidal mar

61 indicators of tipping points, like critical slowing down and flickering.

62 ts by incorporating scaling laws of critical slowing down as a strategy applicable to other complex s

63 lts indicate that the phenomenon of critical slowing down can provide a powerful tool to probe the re

64 re we show experimentally that tree shade is slowing down changes in below-canopy communities due to

65 ion at warm temperatures, rather than simply slowing down deterioration by cooling.

66 ies, but only kinetically stabilizes them by slowing down gravitational creep to ~2 months.

67 the first report of scaling laws of critical slowing down in an experiment.

68 gue that such slow system response resembles slowing down in recovery rates prior to a critical trans

69 We find critical slowing down in the data at the level of California and

70 it as the length of the bridge is increased, slowing down iSF relative to analogous symmetric dimers.

71 approach remembers old tasks by selectively slowing down learning on the weights important for those

72 back-to-front gradient of the motor protein, slowing down locomotion but promoting antigen capture.

73 dopaminergic sensory neurons, in addition to slowing down locomotion upon sensing a potential bacteri

74 Cells quickly responded to Cu(2+) stress by slowing down metabolism.

75 ease fidelity of transcription elongation by slowing down misincorporation events.

76 that while SAC protects mitotic accuracy by slowing down mitosis, 53BP1 and USP28 function in parall

77 her pro-inflammatory mediators, consequently slowing down muscle stem cell depletion.

78 recise predictions on signatures of critical slowing down near the bifurcation to spiking, quantitati

79 gs 9-13) in the tail-bud correlates with the slowing down of axis elongation.

80 ld potentially reverse the observed trend of slowing down of North Pacific climate variability and it

81 rone to more frequent "regime shifts." Thus, slowing down of North Pacific climate variability can he

82 climate, and systems biology has shown that slowing down of recovery upon perturbations can indicate

83 In addition, a significant slowing down of response speed depending on the warning

84 eleconnections' we hypothesise that observed slowing down of sea surface temperature variability cont

85 Moreover, we find a significant slowing down of the alpha-relaxation time.

86 y for correct nucleotide incorporation, 2) a slowing down of the replication rate after misincorporat

87 The recently studied scaling of critical slowing down offers a refined path to understand critica

88 a magnetic white dwarf, which we find to be slowing down on a 10(7)-year timescale.

89 There have been many attempts at slowing down or even reversing the neurodegenerative pro

90 mediate and the second to stabilise it, thus slowing down or speeding up, respectively, product relea

91 itch is intrinsically temperature sensitive, slowing down PER2 degradation as a result of faster reac

92 plasmonic tapers to generate hot carriers by slowing down plasmons at the taper apex.

93 indered the formation of Fe(II)-Al(III)-LDH, slowing down precipitation at low As(V) concentrations a

94 Despite slowing down precursor conversion rate by multiple order

95 Critical slowing down starts growing appreciably several years be

96 nti-inflammatory diet on aging and health by slowing down telomere shortening.

97 ion factor, reducing mesoderm ingression and slowing down the elongation process.

98 This instability can be prevented by slowing down the homeostatic control.

99 votal role played by ferrotoroidic states in slowing down the magnetic relaxation, in spite of large

100 interaction between NPs and substrate, thus slowing down the Ostwald ripening process during post-ox

101 with nitrogen gas proved to be effective in slowing down the oxidation rate after frying with sunflo

102 that enhancing the accuracy should result in slowing down the process, leading to the so-called speed

103 the apical loop reduce binding affinities by slowing down the rate of complex formation.

104 pproach of a kinetic network by dramatically slowing down the relaxation to the designed ground state

105 g the dispersion in the optical fiber, thus, slowing down the ultrafast signal to time scales easily

106 rmational dynamic plays an important role in slowing down this reaction.

107 a: see text] at the beginning and eventually slowing down to the diffusive spread [Formula: see text]

108 in the pool of active ribosomes, instead of slowing down translational elongation as commonly though

109 "expanding", "shrinking", "speeding up" and "slowing down" ecological processes and interactions, and

110 tical and laboratory studies, this 'critical slowing down' remains largely untested in the complex se

111 responds to a critical transition exhibiting slowing down, 2) the scaling laws suggest a saddle-node

112 suggest a saddle-node bifurcation governing slowing down, and 3) these precise scaling laws can be u

113 The recent progress, however, has been slowing down, and many important drug delivery problems

114 l assumption of indicators based on critical slowing down, can break down in this system when multipl

115 Cancer prevention occurs by arresting, slowing down, or reversing the carcinogenic process befo

116 ic episodic diseases, indicators of critical slowing down, such as rising variance and temporal corre

117 the transition--a phenomenon called critical slowing down.

118 ng of low-abundance proteins by mechanically slowing-down their diffusion within the cytoplasm of liv

119 s, repressing internal cryptic promoters and slowing elongation.

120 ening surface lifetimes by pharmacologically slowing endocytosis was sufficient to increase arrestin-

121 Despite their importance for preventing or slowing extinctions and preserving biodiversity, conserv

122 ce, improving glucose tolerance and modestly slowing fat mass gain.

123 with Alzheimer disease and the difficulty in slowing functional decline.

124 ide reduces postprandial glycemia, partly by slowing gastric emptying, although its impact on small i

125 ective than increasing the energy density in slowing gastric emptying.

126 le by epoxidation of the OND linkers without slowing gelation.

127 Consistent with conduction slowing, genes encoding molecular determinants of atrial

128 e male sex workers within the context of the slowing global HIV pandemic.

129 bow trapping is related to the progressively slowing group velocity, and the extremely low group velo

130 receptor depleted cholesterol in GBM cells, slowing growth of GBM xenografts.

131 ough the PSM, although the dynamics of clock slowing have not been well characterized.

132 The exact origins of this slowing, however, have not been established.

133 regional activations to p(Stop) to response slowing in a stop signal task.

134 on into myofibroblasts and rescue conduction slowing in an in vitro model of cardiac interstitial fib

135 s, thermal hypoalgesia, and nerve conduction slowing in diverse rodent models of diabetes.

136 Notably, OM induced a slowing in krel with 1.0 mumol/L OM but not with 0.5 mum

137 based learning (P = 0.028) and (2) a general slowing in processing speed (P < 0.001) and a shift in p

138 unexpected infant death has contributed to a slowing in the decline of these deaths.

139 nly slight (and statistically insignificant) slowing in the rate of MgADP release.

140 ventricular myocytes, as well as conduction slowing in the right ventricular outflow tract region.

141 videnced by a greater enhancement in Pdf and slowing in the time course of cooperative XB recruitment

142 Slowing is a common feature of ageing, yet a direct rela

143 R258C filaments more slowly than WT, and the slowing is exacerbated by smooth muscle tropomyosin.

144 , we show that activity-dependent conduction slowing is produced by the accumulation of intraaxonal s

145 over time, but the mechanism governing this slowing is unclear.

146 the properties of a tension-sensing anchor, slowing its actin-detachment kinetics by two orders of m

147 e of glutamate in the extracellular space by slowing its clearance by astrocytes.

148 Arsenite also stabilized GADD34 protein, slowing its degradation.

149 cyclin-B1 stability in the nucleus, thereby slowing its nuclear accumulation.

150 stance evolution, delaying its emergence and slowing its spread.

151 This slowing may be of importance in enhancing chemical decon

152 Prematurely slowing MCM loading in pluripotent cells not only length

153 as associated with anhedonia and psychomotor slowing measured by the finger-tapping test, simple reac

154 tibiotic and other environmental stresses by slowing metabolism.

155 Overnight orthokeratology was effective in slowing myopia progression over a twelve-year follow-up

156 ropine 0.01% eyedrops were more effective in slowing myopia progression with less visual side effects

157 ting Angpt1, reducing vascular leakiness but slowing niche recovery.

158 Indeed, slowing NMD by inhibiting late-acting factors triggers U

159 nd/or alter relative state energies, thereby slowing nonradiative loss of charge-transfer energy.

160 ent inhibition of proton release but rather, slowing of a previously unrecognized kinetic phase invol

161 myloidosis, which may be owing to a dramatic slowing of Abeta turnover, increasing the likelihood of

162 vity, the increase in F-actin resulting from slowing of actin disassembly, and the increased Arp2/3 r

163 imulation (>/=1 Hz) results in a progressive slowing of action potential conduction velocity, which m

164 The behavioral RT slowing of adult ADHD patients was based on a summation

165 rmination (n=1), organization (n=3), or >10% slowing of AF cycle length (n=8).

166 progenitor cell-secreted exosomes led to the slowing of ageing.

167 d the experimentally observed mass-dependent slowing of barrier crossing.

168 these results demonstrate that inhibition or slowing of canonical pre-mRNA processing events shifts t

169 projected C stock changes indicate a gradual slowing of carbon accumulation with anticipated forest a

170 site annihilation and reordering, and thus a slowing of cation transport.

171 eled cellulose synthase complexes revealed a slowing of cellulose synthase complexes in shv3svl1 comp

172 However, there has been a slowing of cessation rates in the United States during r

173 u) dependence, impact on NMDAR Glu EC50, and slowing of channel deactivation.

174 The spine-dependent slowing of Cl(-) diffusion affected the amount and spati

175 Should the slowing of clinical decline be confirmed in ongoing phas

176 This is accompanied by a slowing of clinical decline measured by Clinical Dementi

177 ccount the baseline B vitamin status, show a slowing of cognitive decline and of atrophy in critical

178 negative voltages (p.A749G) or by pronounced slowing of current inactivation during depolarizing stim

179 that this occurs through Dispatched-mediated slowing of cytoneme retraction rates.

180 The slowing of deactivation by RPR was proportional to the n

181 polarizing shift in voltage sensitivity, and slowing of deactivation in response to a depolarizing pr

182 by several different mechanisms, including a slowing of deactivation, an increase in single channel o

183 pe subunits were required to achieve maximal slowing of deactivation.

184 undaries change, which results in post-error slowing of decisions.

185 oxidation of Pol delta reveal a significant slowing of DNA synthesis that can be fully reversed by r

186 fusive dynamics, and the drastic exponential slowing of DNA, up to approximately 300x, arise from the

187 Slowing of dopamine transients is observed with age in l

188 Rg3 also induced slowing of ERG1, ERG3, and ELK1 channel deactivation and

189 vity with gain-of-function, characterized by slowing of fast inactivation, acceleration of its recove

190 There was a protein load-dependent slowing of gastric emptying, an increase in concentratio

191 The slowing of glutamate uptake depends on the frequency and

192 Interestingly, the slowing of glutamate uptake is specific to activated syn

193 Activity-induced slowing of glutamate uptake, and the increased persisten

194 y fellowships (34 per year) will result in a slowing of growth after 2025, a rate of 56 will generate

195 times were selected covering the progressive slowing of growth and induction of oil synthesis between

196 ities decrease, which causes the progressive slowing of growth rates.

197 it exhibit a phenotype including unexplained slowing of heart rate (bradycardia).

198 nnels play a central role in parasympathetic slowing of heart rate.

199 RPR) induces a pronounced, voltage-dependent slowing of hERG1 deactivation.

200 ced concurrent Kv3.4 current attenuation and slowing of inactivation.

201 hKCNE4 slowing of Kv4.2 inactivation and positive-shifted stead

202 ived position, perceptual slow-speed biases, slowing of motions shown in visual periphery, and the we

203 the behavioural level, we observed a marked slowing of movement preparation and selection when patie

204 glycolytic enzymes in muscle that mediates a slowing of muscle glycogen depletion and lactic acid acc

205 pment revealed an unexpected and substantial slowing of parasite maturation in acutely infected mice,

206 ro at nonzero momentum, indicating dynamical slowing of plasma fluctuations and crystallization of th

207 Potentiation was also accompanied by slowing of receptor desensitization and an increase in p

208 nt block was best explained by a significant slowing of recovery from fast and slow inactivation with

209 CK-2066260 induced a slowing of relaxation, which was markedly larger at 26 d

210 results in accumulation of RNA-DNA hybrids, slowing of replication forks, and increased DNA damage.

211 Behaviorally, TMS caused a relative slowing of response times to targets contralateral to st

212 away from on-beat times was expressed in the slowing of responses to on-beat targets, but not in the

213 This quiescence is characterized by a slowing of S phase, a block to M-phase entry, and the ab

214 s and signs (changes in volition/motivation, slowing of speech, anxiety, other physical symptoms, and

215 However, due to the slowing of the antibiotic pipeline and the rapid emergen

216 nges in kinetic properties, most notably the slowing of the apparent ATP hydrolysis step (reduced 5-9

217 This gradual slowing of the clock in the anterior PSM creates peaks o

218 rneurons caused an increase in amplitude and slowing of the delta rhythm until each period became the

219 he primary proton acceptor residue (D97) and slowing of the light-driven conformational change.

220 Treated animals showed a significant slowing of the progression of disease with weight loss a

221 hough HCC incidence continues to increase, a slowing of the rate of increase occurs around 2006.

222 sociation with AMPARs inhibits CNIH2-induced slowing of the receptors in heterologous cells.

223 barrier of the Dy2 nodes, but rather from a slowing of the relaxation rate of incoherent quantum tun

224 Since the slowing of the trend of increasing surface air temperatu

225 olves decreased intrinsic excitability and a slowing of TIDA network rhythms.

226 This slowing of visual processing would increase light sensit

227 doxically, with ageing and falls, initiation slowing of voluntary stepping is observed together with

228 f this decline has raised the possibility of slowing or delaying age-related kidney disease.

229 didates for modification in drugs capable of slowing or even preventing the onset of PD.

230 thought to interfere with DNA replication by slowing or impeding replication fork progression.

231 s inhibition could be a promising option for slowing or preventing progression of the condition to en

232 leptiform activity on EEG, and developmental slowing or regression.

233 munosuppression is occasionally effective in slowing or reversing the progression of disease though a

234 comes at a time when yield improvements are slowing or stagnating as the approaches of the Green Rev

235 This recruitment drives slowing or stalling of DNA replication at transcriptiona

236 n the face of errors, measured as post-error slowing (PES), and whether this is represented in electr

237 s often slow down after mistakes (post-error slowing [PES]), but the neural mechanism and adaptive ro

238 ting both pathways will be more effective at slowing photoreceptor cell death caused by elevated cGMP

239 ses by 1 A, elevating the energy barrier and slowing polymerization compared with dNTP.

240 Systemic sunitinib malate may be useful in slowing progression of ocular disease from VHL-associate

241 ive in controlling plaque and gingivitis and slowing progression of periodontitis; however, its influ

242 s as both a tumor suppressor and promoter in slowing proliferation while orchestrating a metastatic p

243 1 to 0.45, P<0.05) and increased psychomotor slowing (R=-0.35, P=0.015).

244 ng in Hospital Compare was associated with a slowing, rather than an improvement, in the ongoing decl

245 it the visual cycle isomerase RPE65, thereby slowing regeneration of 11-cis-retinal and reducing prod

246 behavioral inhibition and levodopa reducing slowing related to being responsible for another's fate.

247 ) is safe and more effective than placebo in slowing renal function loss in patients with diabetic ne

248 raquine by increasing cure rates and thereby slowing resistance development.

249 orting antibiotic susceptibility profiles on slowing resistance spread.

250 ygen (O2 ) consumption in a paracrine way by slowing respiration at the mitochondrial electron transp

251 Findings suggest that slowing responses of spreading flames to sudden changes

252 The slowing responses of well-fed and food-deprived animals

253 on to reproductive isolation and potentially slowing speciation.

254 By slowing substrate delivery to lysosomes, autophagosome m

255 nsory evoked potentials demonstrated central slowing supporting myelopathy (96%).

256 nosine-sensitivity (termination or transient slowing/suppression) in response to adenosine was 100% s

257 imers at physiological ATP concentrations by slowing the actin-independent release of Pi.

258 ces by maintaining dead-wood habitats and by slowing the atmospheric contribution of CO2 from the wor

259 S may provide an arrhythmogenic substrate by slowing the Ca(2+) transient decline, as well as by ampl

260 nts, we provide an outline of the mechanisms slowing the cell cycle at and around the time of MBT.

261 tion, which can be used to determine whether slowing the dimerization of vitamin A can prevent vision

262 Slowing the evolution of antimicrobial resistance is ess

263 A segregation prevents cell division without slowing the exponential elongation rate.

264 ent efforts to increase healthspan centre on slowing the fundamental biological processes of ageing s

265 doses of antibody; reactions were reduced by slowing the infusion rate for later patients.

266 est of damaged mitochondria and consequently slowing the initiation of mitophagy.

267 f the samplers might have acted as sorbents, slowing the migration of the dissolved species into the

268 thin individual DNA chains at the expense of slowing the overall rate of damaged base removal from a

269 made in characterizing and pharmacologically slowing the progression of AML and LAM with rapamycin, o

270 f clinical studies testing RAS inhibitors in slowing the progression of cystic disease in ADPKD are i

271 decreasing HIF1A levels while simultaneously slowing the progression of HIF3A expression until the mi

272 rmacological therapies that are effective in slowing the progression of idiopathic pulmonary fibrosis

273 zheimer's disease, effectively preventing or slowing the progression of the disease.

274 Despite the overall success of HAART in slowing the progression to AIDS in HIV-infected subjects

275 Na by altering steady-state inactivation and slowing the rate of Nav1.5 inactivation.

276 ow failure, are believed to drive disease by slowing the rate of protein synthesis.

277 e sheets, glaciers, and groundwater pumping, slowing the rate of sea level rise by 0.71 +/- 0.20 mill

278 to become an increasingly major obstacle to slowing the rate of species extinctions.

279 No polymorphisms were associated with slowing the rate of worsening in Parkinson symptoms from

280 PP plays a multifaceted role, slowing the reaction by complexing both Mn(II) and Mn(II

281 tance might need deliberate tactics aimed at slowing the reduction in ACT effectiveness.

282 also stabilizes the phenolate intermediate, slowing the release of fluoride ions.

283 creased or increased sleep, respectively, by slowing the repetitive discharge of dFB neurons in the O

284 idual-level behavioral phenotype is unclear, slowing the search for functional neuroimaging biomarker

285 in the right ear (50% lower than the voltage slowing the sinus rate).

286 We find that slowing the spread of P. ramorum is now not possible, an

287 The hairpin acts as a road block slowing the translocation rate.

288 alogram findings progressed from generalized slowing to bilateral periodic lateralized epileptiform d

289 outcomes that matter most to patients, thus slowing transformation to higher-value team-based care.

290 No disease-slowing treatment exists for Huntington's disease, but i

291 e infiltration of leukocytes into the tumor, slowing tumor growth and preventing metastasis in poorly

292 ncreasing the anti-tumor T-cell response and slowing tumor growth.

293 wing radiation to have increased efficacy in slowing tumor growth.

294 a slow transporter, generating power without slowing under 1-pN loads that would stall Myo1b.

295 Activity-induced latency slowing was in contrast the most pronounced in Nav 1.8 K

296 en coated on human skin, they are capable of slowing water evaporation and keeping the tissue hydrate

297 lly low water potential (Psiplant ), thereby slowing water loss, stabilizing Psiplant and protecting

298 behavioral indices of distraction-filtering (slowing when distracters might occur) and negatively wit

299 rmality depended on the degree of conduction slowing which in turn depends upon the frequency of stim

300 at the ERN predicted consecutive behavioural slowing within subjects, whereas its overall amplitude d