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1 enterocolitis, but the absolute reduction is small.
2 fficacy between antidepressant therapies are small.
7 bunit that noncovalently associates with the small alpha subunit on the intermembrane space side of t
8 beta2 activation because trimming the Phe by small amino acid substitutions abolished alphaLbeta2 bin
15 and Assembly Based ReAlignment are used for small and large indel detection, and results are present
16 selectively eliminated enteric glia from the small and large intestines, but caused no defects in epi
17 on of the complete RNA cargo, including both small- and long-RNAs, in a single library preparation st
20 ion are analysed by simultaneous synchrotron small-angle X-ray scattering and Raman spectroscopy in a
21 ar weight of the complex was calculated from small-angle X-ray scattering data and was in good agreem
22 ate the RNA secondary structure information, small-angle X-ray scattering data, and any readily avail
23 tional profiling of LmnaH222P/H222P mouse, a small animal model of LMNA cardiomyopathy, suggested dec
31 aliana) have demonstrated that auxin-induced SMALL AUXIN UP RNA (SAUR) genes promote elongation growt
32 ile stoichiometric Ga2FeO4 NCs are intrinsic small bandgap semiconductors, off-stoichiometric GFO NCs
35 morphological alterations in and around the small bowel, MDCTE seems to be an attractive modality fo
40 ent protein fusions to the amino terminus of small capsid protein VP26 are the most widely used metho
41 of the most frequently mutated genes in non-small cell lung cancer (NSCLC) and is commonly comutated
44 ntly in clinical trials for the treatment of small cell lung carcinoma, was synthesized using this st
46 ly or histologically confirmed limited-stage small-cell lung cancer, Eastern Cooperative Oncology Gro
47 nd endowed all dendritic varicosities with a small-center, strong-surround receptive field, which var
49 uld be near a tipping point where relatively small changes to their fire regimes or their postfire fo
51 ed effect of urban form on NO2 is larger for small cities (beta x IQR = -0.46 for cities < approximat
53 ing delayed rectifier current (IKs ) and the small conductance Ca(2+) -activated potassium (SK) curre
54 inematic (e.g., velocity), but also showed a small contribution from the other motion kinematic (e.g.
57 ts that show that proteins are assemblies of small cooperative units called foldons and that a number
65 PFAS were cross-sectionally associated with small differences in markers of insulin secretion and be
66 bronchoalveolar lavage, large proximal, and small distal airway brushings were collected from patien
67 s to the light guiding in optical fibers and small distance between the fiber tips and trapped partic
69 determination of ligand selectivity both for small drugs and large proteins with nearly base-pair res
70 d from nonlinear mixed-effects models showed small early favorable changes in the first few months po
71 for primary care in rural Gambia had a very small effect on linear growth and did not reduce morbidi
77 In addition, the model results suggest that small external electrical signals play a greater role in
79 hese effects and the characterization of the small F508del-CFTR subpopulation might be crucial for CF
80 se of a genome-wide analysis of members of a small family of immunoglobulin domain proteins, we found
81 crop essential to the food security of many small farmers in Asia and Africa and is a model system f
82 lp in screening patients for the presence of small fibre neuropathy and to assess disease progression
84 f of Thailand, Bryde's whales, which feed on small fish species [3], predominantly anchovies, demonst
86 with preterm birth (ARR, 1.16) but not with small for gestational age (ARR, 1.19), stillbirth (ARR,
87 (OR, 1.34 [95% CI, 1.18-1.52]) but not with small for gestational age (OR, 1.01 [95% CI, 0.81-1.25])
88 l nutritional status is a key determinant of small for gestational age (SGA), but some knowledge gaps
89 2.2 weeks; P<0.001), with increased rates of small for gestational age births (15% versus 8%; P=0.03)
90 evalence of preterm birth, low birth weight, small-for-gestational-age births, cesarean delivery, and
91 lation of selected candidate genes or a very small fraction of genomic CpG sites in human pancreatic
93 th will inevitably be appropriated by a very small fraction of the population unless effective wealth
95 100x higher than generic statins, and only a small fraction of their higher cost is likely to be reco
96 ditions were found to be concerted involving small free activation energies and are all exoenergonic.
101 nder conditions promoting protein unfolding, small heat shock proteins (sHsps) prevent the irreversib
102 nsistent with STEMI at primary care clinics, small hospitals, and PCI hospitals in the southern state
103 was found although the sample size used was small; however, the results excluded greater than a smal
104 c telomere-length measurements in relatively small human cardiac samples and offers an attractive tec
106 0.65 for not worsening, 0.68 for at least a small improvement, 0.69 for at least a moderate improvem
107 ation in QoL, 9.2% had no change, 9.2% had a small improvement, 13.5% had a moderate improvement, and
109 techniques, cataract surgery has evolved to small-incisional surgery with rapid visual recovery, goo
110 enatal exposure to PFASs was associated with small increases in adiposity measurements in mid-childho
112 scribed here to identify enhancer-associated small insertion variants provides a foundation for furth
113 de variants (SNVs), with the contribution of small insertions and deletions (indels) less well charac
114 of extreme facial features (e.g., very large/small inter-eye distance), and reduction of the gain of
116 ajor histocompatibility complex molecules by small interfering RNA targeting of class II transactivat
117 h as nonsteroidal anti-inflammatory drugs or small interfering RNAs (siRNAs) against COX-1 and COX-2,
122 enterocyte surface in the mid-region of the small intestine and translocate through the epithelial c
123 provides a noninvasive option to assess the small intestine, but its use with respect to endoscopic
124 6SF2 is expressed predominantly in liver and small intestine, sites for triglyceride-rich lipoprotein
127 deltaN/N for CP-AFM junctions is remarkably small (</=2%) and that the largest contributions to delt
128 iron (<0.025 mum) at pH 4 but principally as small (<0.45 mum) iron oxyhydroxide particles at pH 8 wi
129 n addition, it remains challenging to access small luminal organs or pass through narrow luminal sect
130 ents with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) that was maintained at
131 the underlying lattice, as evidenced by the small magnitude of the magnetostriction anomaly at H*.
132 ed tight UF hollow fibers not only possess a small mean pore diameter of 1.0-1.3 nm with a molecular
133 l modification of cellular proteins with the small modifier, ubiquitin (Ub), regulates virtually ever
134 nts an advancement toward the development of small molecule activators of tumor suppressor proteins.
139 ver fibrosis, we sought to identify improved small molecule functional mimetics of H2-RLX with select
140 tion, and support the further development of small molecule Gas6-TAM interaction inhibitors as a nove
141 ion of the drebrin/EB3 pathway using BTP2, a small molecule inhibitor of drebrin binding to actin fil
142 between GAS6 and AXL and the promiscuity of small molecule inhibitors represent important challenges
144 ated that extracellular matrix organization, small molecule metabolic process, cell adhesion (GO IDs:
150 y-enabled high-throughput screen to identify small-molecule agonists of TFEB and discover three novel
153 he molecular effects of a recently developed small-molecule inhibitor of the KDM5 family of proteins
154 , summarizes the current status of exogenous small-molecule inhibitors of RAGE and concludes by ident
156 The discovery of nonnucleoside, reversible, small-molecule inhibitors with greater specificity again
157 Advances in the synthesis and screening of small-molecule libraries have accelerated the discovery
160 erent types of amphiphiles (both polymer and small-molecule surfactants) were guided to form hetero-v
162 y was to develop and characterize a specific small-molecule tracer for PET imaging that binds with hi
165 compounds and efforts toward development of small molecules and biologics that could be of therapeut
166 sults establish potent Sirt6 activation with small molecules and provide a structural basis for furth
168 ptors, was optimized using CCS values of 205 small molecules and validated using a set of 131 pestici
170 ing mass spectrometry, we generated a map of small molecules differentially expressed in the Drosophi
171 ) as a label-free approach to chemically map small molecules in aggregated and single Escherichia col
172 icularly in the gut, and at least 20% of the small molecules in human blood are products of the micro
173 e efforts also determined that many of these small molecules inhibit the protein-protein interactions
174 raises the possibility that HMBA or related small molecules may be explored as therapeutic adjuvants
176 y accurate quantifications of the effects of small molecules on specific microscopic steps in Abeta42
178 Together, these observations establish that small molecules that bind to the interface between TAM I
179 ruggable targets and identify a new class of small molecules that may be further optimized for the re
182 roperties (e.g., self-assembling ability) of small molecules with the efficacy of a molecule process
183 d be used to screen for structural elements, small molecules, and host factors that alter these relat
184 ervations indicate that the self-assembly of small molecules, as multifaceted entities and processes
185 ilizing specific 14-3-3 protein complexes by small molecules, peptide mimetics, and natural products.
186 d by oxidative oligomerization of catecholic small molecules, the physical properties of melanins are
188 broaden sequence recognition of DNA-targeted-small-molecules to include both A.T and G.C base pairs,
191 ly, this elastic behavior is transferable to small networks, where we found the surprising effect tha
194 NAs) are 26-30-nucleotide germ line-specific small non-coding RNAs that have evolutionarily conserved
198 RNA splicing.IMPORTANCE The Parvovirinae are small nonenveloped icosahedral viruses that are importan
200 omes, all mRNAs, and non-coding RNAs such as small nucleolar RNAs (snoRNAs) and long non-coding RNAs
202 funding of career development grants, only a small number of early-career American College of Cardiol
203 se included, in particular, tuning to only a small number of facial features that were often related
204 jor predictor of transcriptomic variation; a small number of genes (n = 263) were differentially regu
209 roach we demonstrate that the frequency of a small number of linear motifs three amino acids in lengt
210 olution structures available, leaving only a small number of protein-ssNA crystal structures, while f
214 we use computational methods to investigate small numbers of bonds at the interface between two memb
215 tatistical power, most studies identify only small numbers of candidate genes that pass the conventio
216 n most natural infections or after recovery, small numbers of Leishmania parasites remain indefinitel
218 and microencapsulate lipid fraction, so that small oil droplets are entrapped within a dry matrix of
219 erates short peptides, some of which are too small or uninformative for optimal analysis and which po
221 ploring an ionization method that can ionize small organics and large biomolecules with different pro
226 n reduce sensitivity, such as probing only a small percentage of the nanoprobes present in the sample
227 advertising for mates by taking advantage of small, periodic decreases in the overall noise structure
228 of the hybrid mimic lines, whereas in the F6 small phenotype line, the 12 segments were each derived
229 with Lewy bodies cases mainly in the form of small phosphorylated alpha-synuclein aggregates that are
230 s developing disease in their twenties and a small portion of carriers surviving to their ninth decad
232 sis, although conventional regression gave a small positive association (0.02 higher grade, 95% CI: 0
234 ed strain sensors are incapable of resolving small pressure changes in the few kPa range, making them
238 S1 (EXCESS MICROSPOROCYTES1) LRR-RLK and its small protein ligand TPD1 (TAPETUM DETERMINANT1) play a
240 o be radical in nature, with the addition of small quantities of a radical initiator (azobis(isobutyr
241 double-blind randomised controlled trial of small-quantity lipid-based nutrient supplements (SQ-LNS)
245 ce on the electrical transport behavior of a small-resistance GaSb sample and explained the discontin
246 th most patients; however, some GBCAs have a small risk of adverse effects, including nephrogenic sys
247 The nict-1 locus contains a Piwi-interacting small RNA (piRNA) cluster; we observe that the Piwi Argo
248 EMB-4 as a direct and essential link between small RNA pathways and the transcriptional machinery in
251 t deep sequencing technology to sequence all small RNAs and degradome of sweetpotato for systematical
252 eir mechanism of action and show that mobile small RNAs generate sharply defined domains of target ge
254 ysis of gene expression, DNA methylation and small RNAs in the rice endosperm and functional tests of
255 NMR metabolite profiling was achieved from a small sample of intact sausage after 0, 2, 4, 7, 11 and
257 irculating tumor cells requires manipulating small sample volumes without loss of rare disease-causin
264 ove cross-cultural life history datasets for small-scale societies for which reliable age records are
266 e cardioverter-defibrillator (ICD) shocks in small series of patients with structural heart disease (
267 here is necessarily an imbalance between the small set of available disease-associated and the much l
274 Arctic fish communities, mainly composed of small-sized bottom-dwelling benthivores, are being rapid
279 producible heat-dependent gene expression in small sublineages (one to four cells) without radiation
280 ed rapid and transient NPAS4 expression in a small subpopulation of FOS-positive neurons in the NAc.
282 its a very high level of selectivity towards small substrates including the natural indole-3-acetic a
285 as well as the energy density extracted from small synthetic samples allows planning potential uses o
288 ations for low back pain are associated with small to moderate, primarily short-term effects on pain.
292 cellular proteins through the conjugation of small ubiquitin-related modifier (SUMO) and comprises an
294 beetles (Nicrophorus vespilloides) breed on small vertebrate carcasses, which they shave and smear w
296 non-demyelinating disorders such as chronic small vessel disease and other inflammatory, granulomato
299 m the Vif-A3G and Vif-A3F interfaces, with a small Vif region being important for recognition of both
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