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1 stitutes of Health (NIH) Clinical Collection small molecule library.
2 eestatin using a high-throughput screen of a small molecule library.
3 h pocket was identified and screened using a small molecule library.
4 omers through high-throughput screening of a small-molecule library.
5 hat was recently isolated from a DNA-encoded small-molecule library.
6 s platform to screen the 300,000+ member NIH small-molecule library.
7 activity, we screened 114,752 compounds of a small-molecule library.
8 robust and flexible biologically synthesized small-molecule library.
9 ter plates and treated with compounds from a small-molecule library.
10 n, and structure-activity relationships of a small molecules library.
11 y used in drug discovery, using a variety of small molecule libraries.
12 p75NTR was applied to in silico screening of small molecule libraries.
13 of an OBOC combinatorial peptidomimetic and small molecule libraries.
14 s of food contaminants and drug screening of small-molecule libraries.
15 oric model for searching new drug leads from small-molecule libraries.
16 nable direct in vivo phenotypic screening of small-molecule libraries.
17 eactions starting from a large collection of small-molecule libraries.
18 screening of a diverse set of mixture-based small-molecule libraries.
19 s can be identified through the screening of small-molecule libraries.
20 fication of DNA sequences encoding synthetic small-molecule libraries.
21 synthesis of much larger (>10,000-membered) small-molecule libraries.
22 to assess the quality of large DNA-templated small-molecule libraries.
23 ully exploit the power of OBOC combinatorial small molecule libraries, a robust and high throughput e
24 dy serves as a cautionary tale for screening small molecule libraries and provides insights into the
26 We screened RIP1 against GSK's DNA-encoded small-molecule libraries and identified a novel highly p
27 ategy in the construction and selection of a small molecule library, and successfully identified inhi
28 and effectors of biological reactions using small molecule libraries are often hampered by interfere
30 n the combinatorial synthesis of peptide and small-molecule libraries, as catalyst and reagent suppor
31 a cell-based high-throughput screening of a small-molecule library based on TLR3-mediated NF-kappaB
32 h the creation of a natural product-inspired small-molecule library bearing protein-reactive elements
34 s identified by virtual screening from a NCI small molecule library, but no data were available about
35 method to screen an epigenetically targeted small molecule library by evaluating regions of aberrant
36 synthesis minimizes the effort to synthesize small-molecule libraries by labelling the molecules rath
37 , two on the RNA and one on the S15 protein, small-molecule libraries can be screened for potential i
38 Ebola proteins with human proteins and with small-molecule libraries, computational modeling of the
39 ry against the entire druggable genome and a small-molecule library consisting of 691,200 compounds u
40 ed by the synthesis and screening of a model small molecule library containing 84 672 member compound
45 te that cell-based high-content screening of small molecule libraries for their ability to block bind
46 mal and malignant T lymphoblasts to screen a small molecule library for activity against immature T c
47 idate the method by successfully screening a small molecule library for compounds capable of inhibiti
48 ssible therapeutic agents, we have assayed a small molecule library for in vitro inhibition of Cdc25.
49 hological settings, we previously screened a small molecule library for novel autophagy-enhancing fac
50 c domain (MUC1-CD) was established to screen small-molecule libraries for compounds that block its di
53 an HDAC inhibitor as an enhancer to screen a small-molecule library for compounds inducing neuroblast
54 ilding on this foundation, we interrogated a small-molecule library for compounds that prevent DEPTOR
56 ospho-specific flow cytometry, we screened a small-molecule library for inhibitors of T cell-receptor
58 aign was conducted to interrogate a 380,000+ small-molecule library for novel D2 dopamine receptor mo
62 Advances in the synthesis and screening of small-molecule libraries have accelerated the discovery
65 uracil recognition mechanism to build large small-molecule libraries in which uracil is tethered via
66 f one bead-one compound (OBOC) combinatorial small molecule libraries is described here, whereby libr
69 high-throughput screening of 39,000-compound small molecule libraries, leading to identification of f
73 vae to in vivo high-throughput screenings of small molecule libraries makes these models a valuable t
74 proach, we identified several molecules in a small molecule library of 10 000 compounds that could in
78 luciferase complementation assay to screen a small molecule library of kinase inhibitors against the
79 ds were obtained from commercially available small-molecule libraries (Prestwick and Chembridge).
80 interest, while high-throughput screening of small molecule libraries provides potential inducers.
81 cal approach by synthesizing and screening a small molecule library, reminiscent of the polycyclic in
82 differentiation assay was screened against a small molecule library resulting in a 1,4-dihydropyridin
83 failed to reveal any druggable targets, the small-molecule library screen identified a class of alky
84 acetate HIF-1 inhibitors identified from the small-molecule library screen were also found to target
85 K-3alpha) in AML by performing 2 independent small-molecule library screens and an shRNA screen for p
86 translation of DNA sequences into synthetic small-molecule libraries suitable for in vitro selection
87 by high-throughput screening of fluorescent small-molecule libraries synthesized with a diversity-or
89 imetic library as an integral component of a small-molecule library targeting protein-protein interac
90 turn mimetic library as a key component of a small-molecule library targeting the major recognition m
91 fficient construction of performance-diverse small-molecule libraries that are enriched in bioactives
92 SC668036) from the National Cancer Institute small-molecule library that can bind to the Dvl PDZ doma
93 oughput screening of synthetic combinatorial small molecule libraries to identify inhibitors of arena
94 rformed structure-based virtual screening of small-molecule libraries to seek inhibitors of the Pfn1-
96 he virus life cycle and enables screening of small-molecule libraries under biosafety containment lev
97 identify AML1-ETO modulators, we screened a small molecule library using a chemical genomic approach
100 MR-based screening approach on a preselected small-molecule library, we identified several compounds
101 e database and seven computationally derived small molecule libraries were used to evaluate this appr
102 een of the National Cancer Institute 140,000 small-molecule library were tested in a 96-well plate EL
104 challenge by creating a fully functionalized small-molecule library whose membership is endowed with:
105 To validate this methodology, a model OBOC small molecule library with 12,288 members was synthesiz
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