ライフサイエンスコーパス: small nuclear RNA

1 hylation at cap 1 on substrate SL RNA and U1 small nuclear RNA.

2 huttling, we demonstrate the shuttling of U1 small nuclear RNA.

3 tional regulation of the expression of an Sm small nuclear RNA.

4 in but with a 10-fold lower affinity than U1 small nuclear RNA.

5 binding to an RNA hairpin (U1hpII) in the U1 small nuclear RNA.

6 that alter either the protein U1-C or the U1 small nuclear RNA.

7 oncanonical mechanisms of base pairing to U1 small nuclear RNA.

8 A' protein complex and hairpin-loop IV of U2 small nuclear RNA.

9 ks generated with P120-4SU+2 contain the U11 small nuclear RNA.

10 ox C/D and H/ACA small nucleolar RNAs and U4 small nuclear RNA.

11 ting its association with the inhibitory 7SK small nuclear RNA.

12 and an H/ACA guide RNA, modify ribosomal and small nuclear RNAs.

13 P structure that contains the U2, U5, and U6 small nuclear RNAs.

14 ike Sm and like-Sm core peptides, which coat small nuclear RNAs.

15 the modification of ribosomal RNA and other small nuclear RNAs.

16 ing frames, 236 transfer RNAs (tRNAs) and 12 small nuclear RNAs.

17 e base-pairing interaction between U4 and U6 small nuclear RNAs.

18 able base pairing between the transcript and small nuclear RNAs.

19 cumulation of pre-tRNAs, pre-rRNAs, and some small nuclear RNAs.

20 rocessing of U6 RNA, one of the spliceosomal small nuclear RNAs.

21 5S and cytoplasmic 7SL as well as U2 and U6 small nuclear RNAs.

22 uclear pre-mRNAs, as well as the majority of small nuclear RNAs.

23 se II transcribes messenger RNAs and several small nuclear RNAs.

24 reading frames (ORFs) plus 13 tRNAs and four small nuclear RNAs.

25 roteins of RNA elements within pre-mRNAs and small nuclear RNAs.

26 enes encoding the messenger RNAs and several small nuclear RNAs.

27 S and 28S rRNAs and levels of the U-class of small nuclear RNAs.

28 it complex required for 3'-end processing of small nuclear RNAs.

29 rimethylguanosine (TMG) caps on spliceosomal small nuclear RNAs.

30 ng RNAs, which share some of the features of small nuclear RNAs.

31 d structural features with cellular Sm-class small nuclear RNAs.

32 vertebrates the export of mRNA, like that of small nuclear RNA, 5S rRNA, and transport factors such a

33 negatively regulated by association with the small nuclear RNA 7SK and the HEXIM1 protein.

34 iation of the large inactive P-TEFb:7SK RNP (small nuclear RNA 7SK ribonucleoprotein) complex and the

35 s inhibited by the coordinate actions of 7SK small nuclear RNA (7SK snRNA) and hexamethylene bisaceta

36 rt that LARP7, BCDIN3, and the noncoding 7SK small nuclear RNA (7SK) are vital for the formation and

37 7), methyl phosphate capping enzyme, and 7SK small nuclear RNA (7SK).

38 two ncRNAs implicated in RNA processing: U1 small nuclear RNA, a component of the spliceosome, and M

39 for catalysis by unwinding base-paired U4/U6 small nuclear RNAs, a step that must be precisely timed.

40 ticular, both types of promoters utilize the small nuclear RNA activating protein complex (SNAP(c)) a

41 C-4, the Myb-like DNA-binding subunit of the small nuclear RNA activating protein complex, binds piRN

42 We identified a zebrafish snapc4 (small nuclear RNA-activating complex polypeptide 4) muta

43 e 57-kDa subunit is orthologous to the human small nuclear RNA-activating protein (SNAP)50, which is

44 scription factors, a partially characterized small nuclear RNA-activating protein complex (SNAP(c)) a

45 sphorylates the general transcription factor small nuclear RNA-activating protein complex (SNAP(C)) t

46 wo of the three TAFs in the pol III-specific small nuclear RNA-activating protein complex (SNAPc).

47 n a unique transcription factor known as the small nuclear RNA-activating protein complex (SNAPc).

48 The small nuclear RNA-activating protein complex SNAP(c) is

49 A, TFIIB, and TFIIH which, together with the small nuclear RNA-activating protein complex, form a tra

50 ll four hypertrophic signals dissociated 7SK small nuclear RNA, an endogenous inhibitor, from cyclin

51 ~160-nt-long RNAs, including spliceosomal U6 small nuclear RNA and a cyclic-di-AMP binding riboswitch

52 The SL RNA is a small nuclear RNA and a trans splicing substrate for the

53 'Sm' sequence motif, form a complex with U6 small nuclear RNA and are required for pre-mRNA splicing

54 partmentalization by fluorophore-labeling U1 small nuclear RNA and observing its distribution in the

55 recursor, proper 3'-end processing of the U4 small nuclear RNA and some small nucleolar RNAs, and deg

56 tein particles (snRNPs), which consist of U1 small nuclear RNA and ten proteins, recognize the 5' spl

57 Any RNA sequence including tRNAs, small nuclear RNAs and 5'ends of mRNAs can become POLADS

58 me, a macromolecular machine containing five small nuclear RNAs and numerous proteins.

59 ent within snatched fragments and found that small nuclear RNAs and small nucleolar RNAs contributed

60 results in the misexpression of a variety of small nuclear RNAs and small nucleolar RNAs, an effect t

61 increases the levels of spliceosomal and U7 small-nuclear RNAs and corrects RNA processing defects i

62 oplasmic fraction, whereas Pem pre-mRNAs, U6 small nuclear RNA, and a spliced intron from another gen

63 The large complex is composed of P-TEFb, 7SK small nuclear RNA, and hexamethylene bisacetamide-induci

64 e the potential to pair with sequences in U1 small nuclear RNA, and mutations disrupting this pairing

65 nd metabolism, including processing of rRNA, small nuclear RNA, and small nucleolar RNA, and mRNA dec

66 nucleolar RNA, natural antisense transcript, small nuclear RNA, and small RNA using published dataset

67 an intricate network formed by U5, U2 and U6 small nuclear RNAs, and a pre-messenger-RNA substrate.

68 small RNAs, including the Epstein-Barr virus small nuclear RNAs, and newly synthesized progeny DNA.

69 ely block nuclear transport of spliced mRNA, small nuclear RNAs, and small nuclear ribonucleoproteins

70 clear organelles that are highly enriched in small nuclear RNAs, and that have long been thought to b

71 Small nuclear RNAs are involved in splicing pre-mRNA, wh

72 r components required to form the 3' ends of small nuclear RNAs are unknown.

73 ade by pol II, including small nucleolar and small nuclear RNAs, are not known.

74 the spliceosome, a macromolecule composed of small nuclear RNAs associated with proteins.

75 EAP (Epstein-Barr virus-encoded small nuclear RNA-associated protein) binds to small non

76 omplexes between the large subunit of the U2 small nuclear RNA auxiliary factor (U2AF65) with the spl

77 thylguanosine (TMG) cap found in many U-like small nuclear RNAs, but a subpopulation of nut-1 RNAs ca

78 esvirus saimiri (HVS) encodes seven Sm-class small nuclear RNAs, called HSURs (for Herpesvirus saimir

79 particular spliceosome components, including small nuclear RNAs, cause reproducible uniquely distribu

80 of three fluorescently tagged molecules: U7 small nuclear RNA, coilin, and TATA-binding protein (TBP

81 exon and a 'U1 domain' that binds to the U1 small nuclear RNA component of the U1 small nuclear ribo

82 ription factor SNAP(C), which binds to human small nuclear RNA core promoter elements and nucleates p

83 NA for post-transcriptional modification and small nuclear RNA duplexes for splicing.

84 nts of the mRNA splicing machinery, comprise small nuclear RNAs, each complexed with a set of protein

85 n strain to screen a collection of mutant U2 small nuclear RNAs, each containing a point mutation nea

86 m albumin, are potent inhibitors of mRNA and small nuclear RNA export.

87 structure of a homologous stem-loop from U2 small nuclear RNA fits closely to the electron density o

88 least two multisubunit protein complexes, a small nuclear RNA-free structure similar to what was rep

89 is is, however, required for displacement of small nuclear RNAs from the Gemin5-containing subunits a

90 uide chemical modifications of ribosomal and small nuclear RNAs, functions that are carried out in th

91 reviously isolated a variant of the human U6 small nuclear RNA gene (87U6) and demonstrated that tran

92 mologous to SNAP50, a component of the human small nuclear RNA gene activation protein complex (SNAPc

93 t is transcribed from the optimized mouse U7 small nuclear RNA gene and contains the 5' stem-loop (p7

94 ne in Leptomonas seymouri is a member of the small nuclear RNA gene family.

95 sequence element (PSE) for the sea urchin U6 small nuclear RNA gene has been defined.

96 sses TAR-2 under the control of the human U6 small nuclear RNA gene promoter and here show that the U

97 Many small nuclear RNA gene promoters are activated by SphI p

98 Many vertebrate small nuclear RNA gene promoters contain an SPH motif in

99 in both RNA polymerase II- and III-dependent small nuclear RNA gene promoters.

100 Human U6 small nuclear RNA gene transcription by RNA polymerase I

101 Human small nuclear RNA gene transcription by RNA polymerases

102 Unlike most protein-coding genes, small nuclear RNA gene transcription starts predominantl

103 mary start site determinant for the yeast U4 small nuclear RNA gene, SNR14.

104 ion assay in which Ty3 is targeted to the U6 small nuclear RNA gene, SNR6.

105 lex SNAP(c) is required for transcription of small nuclear RNA genes and binds to a proximal sequence

106 s a dyad symmetry region located between two small nuclear RNA genes and is located upstream of the d

107 on mechanism differs from that of vertebrate small nuclear RNA genes and the SL RNA homologue in Asca

108 IIIB)-alpha governs basal transcription from small nuclear RNA genes by RNA polymerase III (pol III).

109 e evolutionary distance in the regulation of small nuclear RNA genes in eukaryotes.

110 scription from yeast small nucleolar RNA and small nuclear RNA genes into adjacent genes is prevented

111 and deletion analyses of mammalian class III small nuclear RNA genes transcribed by RNA polymerase (p

112 denylated, RNAPII-dependent, uridylate-rich, small nuclear RNA genes.

113 on factor that is required for expression of small nuclear RNA genes.

114 cript; the RNA polymerase III-transcribed U1 small nuclear RNA has the same first four nucleotides as

115 etween group II introns and the spliceosomal small nuclear RNAs, however, have left this proposal in

116 te snoRNA, small Cajal body RNA (scaRNA) and small nuclear RNA in human and mouse cells by convention

117 nscribed nucleotide of spliced leader and U1 small nuclear RNAs in the kinetoplastid protozoan Trypan

118 uide covalent modifications of ribosomal and small nuclear RNAs in the nucleus.

119 But whether splicing is catalysed by small nuclear RNAs in the spliceosome is unresolved.

120 show that a base-paired complex of U6 and U2 small nuclear RNAs, in the absence of the approximately

121 how that the Gemin5-containing subunits bind small nuclear RNA independently of the SMN complex and w

122 sequesters the 5'ss residues involved in U1 small nuclear RNA interactions, thereby inhibiting excis

123 abilize U6 ACAGAGA stem-pre-mRNA and Brr2-U4 small nuclear RNA interactions.

124 ibonucleoprotein (U1-snRNP) that includes U1-small nuclear RNA is a highly conserved intranuclear mol

125 The 7SK small nuclear RNA is a highly conserved non-coding RNA t

126 e branch site recognition region of yeast U2 small nuclear RNA is absolutely conserved in all eukaryo

127 The U6 small nuclear RNA is post-transcriptionally processed by

128 anism, through which over-accumulation of U6 small nuclear RNA is prevented.

129 The spliceosomal U4 snRNA (small nuclear RNA) is synthesized from a 3' extended pre

130 plex often signals nuclear import for U-rich small nuclear RNAs, it is unclear how this Sm binding si

131 inding protein La recognizes UUU-3'OH on its small nuclear RNA ligands and stabilizes them against 3'

132 teins in the cytoplasm; these RNAs resembled small nuclear RNAs like U1 and U5 RNAs in their bi-direc

133 1 and the SLA1 snoRNP but does not affect U1 small nuclear RNA methylation.

134 deletion strain, but can be suppressed by U2 small nuclear RNA mutations that hyperstabilize U2 stem

135 Seven small nuclear RNAs of the Sm class are encoded by Herpes

136 for full-length U2 than for any of the other small nuclear RNAs or nonspecific RNAs tested.

137 Cus2p and stem IIa-destabilized forms of U2 small nuclear RNA places high demands on the ATP-driven

138 l of motor neuron (SMN) complex delivers pre-small nuclear RNAs (pre-snRNAs) to the heptameric Sm rin

139 The human U6 small nuclear RNA promoter, located 5' of the transcript

140 ngle-guide RNAs that are expressed from a U6 small nuclear RNA promoter.

141 The RNA polymerase II and III human small nuclear RNA promoters have a common basal element,

142 tween ciliate telomerase RNA and metazoan U6 small nuclear RNA promoters.

143 The Brr2 RNA helicase disrupts the U4/U6 di-small nuclear RNA-protein complex (di-snRNP) during spli

144 t contains two Sm motifs found in the common small nuclear RNA proteins and the LSm (like-Sm) family

145 of nucleotides in ribosomal and spliceosomal small nuclear RNAs, respectively.

146 tides 78 to 95, but not other regions, of U6 small nuclear RNA resulted in an inhibition of the depho

147 eview focuses on transport of messenger RNA, small nuclear RNA, ribosomal RNA, and transfer RNA betwe

148 rons has revealed haunting similarities with small nuclear RNA sequences in the spliceosome.

149 ntergenic ncRNAs, small cytoplasmic RNAs and small nuclear RNAs show less consistent patterns.

150 erestingly, these three nucleolus-associated small nuclear RNAs (signal recognition particle RNA, tel

151 regions and the small RNAs, including tRNA, small nuclear RNA, small nucleolar RNA, and microRNA.

152 ed abundant small, noncoding RNAs, including small nuclear RNAs, small nucleolar RNAs (snoRNAs), cryp

153 box of the RNA polymerase III-transcribed U6 small nuclear RNA (SNR6) gene.

154 The small nuclear RNA (snRNA) activating protein complex (SN

155 snRNP) by the coordinated actions of the 7SK small nuclear RNA (snRNA) and hexamethylene bisacetamide

156 uborganelles that nonrandomly associate with small nuclear RNA (snRNA) and histone gene loci in human

157 RNA) splicing requires multiple spliceosomal small nuclear RNA (snRNA) and pre-mRNA rearrangements.

158 The human small nuclear RNA (snRNA) and small cytoplasmic RNA (scR

159 Base pairing between the 5' end of U7 small nuclear RNA (snRNA) and the histone downstream ele

160 d clones spanning the Pol III-transcribed U2 small nuclear RNA (snRNA) and U3 snRNA/7SL RNA gene loci

161 U4 small nuclear RNA (snRNA) and U6 snRNA form a base-paire

162 ed in unwinding the 5' splice site (5'ss)-U1 small nuclear RNA (snRNA) base-pairing, to allow replace

163 es along with the Pol IV subunit NRPD1b; the small nuclear RNA (snRNA) binding protein SmD3; and two

164 fficiency, the ribozyme was inserted into U1 small nuclear RNA (snRNA) by engineering the U1 snRNA ex

165 with U1 and U2 gene loci, which produce the small nuclear RNA (snRNA) component of the respective sn

166 The small nuclear RNA (snRNA) components of the spliceosome

167 Yeast U2 small nuclear RNA (snRNA) contains three pseudouridines

168 Approximately 90% of human U6 small nuclear RNA (snRNA) contains uridine cyclic phosph

169 Approximately 65% of mature human U2 small nuclear RNA (snRNA) ends in 3'-terminal CCA, as do

170 The distal control region of a human U6 small nuclear RNA (snRNA) gene promoter contains two sep

171 Vertebrate U6 small nuclear RNA (snRNA) gene promoters are among the f

172 Human U6 small nuclear RNA (snRNA) gene transcription by RNA poly

173 es of metaphase chromosome fragility: the U1 small nuclear RNA (snRNA) genes (the RNU1 locus), the U2

174 osomal fragile sites corresponding to the U1 small nuclear RNA (snRNA) genes (the RNU1 locus), the U2

175 Most small nuclear RNA (snRNA) genes are transcribed by RNA p

176 RNA polymerase III transcription of human U6 small nuclear RNA (snRNA) genes both negatively and posi

177 Promoters for vertebrate small nuclear RNA (snRNA) genes contain a relatively sim

178 The small nuclear RNA (snRNA) genes have been widely used as

179 The RNA polymerase (pol) II and III human small nuclear RNA (snRNA) genes have very similar promot

180 ty of eukaryotic organisms, transcription of small nuclear RNA (snRNA) genes is dependent upon a prox

181 re highly enriched at RNA Pol II-transcribed small nuclear RNA (snRNA) genes, and the loss of LEC res

182 and RNA polymerase III-transcribed mammalian small nuclear RNA (snRNA) genes, is essential for their

183 case of the human RNA polymerase II and III small nuclear RNA (snRNA) genes, whose core promoters co

184 mRNA-encoding genes and the majority of the small nuclear RNA (snRNA) genes.

185 ed for the transcription of Pol II-dependent small nuclear RNA (snRNA) genes.

186 The viral small nuclear RNA (snRNA) Herpesvirus saimiri U RNA 1 (H

187 2'-O-methylation and pseudouridylation of U6 small nuclear RNA (snRNA) hypothesize that these posttra

188 air with a complementary sequence in the U12 small nuclear RNA (snRNA) in a manner analogous to the p

189 We probe the structure of low-abundance U12 small nuclear RNA (snRNA) in Arabidopsis thaliana and pr

190 The multigene family encoding human U2 small nuclear RNA (snRNA) is organized as a single large

191 editing in mitochondria of trypanosomes and small nuclear RNA (snRNA) maturation in humans.

192 thyl-oligoribonucleotide complementary to U5 small nuclear RNA (snRNA) nucleotides 68 to 88 (BU5Ae) d

193 SK, an abundant and evolutionarily conserved small nuclear RNA (snRNA) of unknown function, as a spec

194 oduct levels is achieved by using a human U6 small nuclear RNA (snRNA) promoter to drive nuclear expr

195 The RNA polymerase II and III small nuclear RNA (snRNA) promoters contain a common bas

196 se structure resembles RNA polymerase III U6 small nuclear RNA (snRNA) promoters.

197 new strategy: expressing a 5' end-mutated U1 small nuclear RNA (snRNA) to inhibit maturation of cypin

198 subunit of a protein complex that regulates small nuclear RNA (snRNA) transcription.

199 for the endonucleolytic cleavage of primary small nuclear RNA (snRNA) transcripts within the nucleus

200 Previously, we showed that spliceosomal U6 small nuclear RNA (snRNA) transiently passes through the

201 se to the catalytic Mg(2+) site in the U2/U6 small nuclear RNA (snRNA) triplex, and the 5'-phosphate

202 vivo association between coilin and rRNA, U small nuclear RNA (snRNA), and human telomerase RNA, whi

203 cleosides from the 3' end of spliceosomal U6 small nuclear RNA (snRNA), directly catalyzing terminal

204 assembled spliceosomal complex comprising U5 small nuclear RNA (snRNA), extensively base-paired U4/U6

205 all nuclear RNP (snRNP), composed of the 7SK small nuclear RNA (snRNA), MePCE, and Larp7, regulates t

206 RNAP II-transcribed cellular RNAs, including small nuclear RNA (snRNA), small nucleolar RNA (snoRNA),

207 pecifically interacts with stem-loop I of U2 small nuclear RNA (snRNA), that C protein disrupts U4:U6

208 , U-rich sequence called the Sm site in each small nuclear RNA (snRNA), to form the core domain of th

209 the survival motor neuron (SMN) protein, U2 small nuclear RNA (snRNA), U5 snRNA, and the small CB-sp

210 ryotic ribosomal RNA (rRNA) and spliceosomal small nuclear RNA (snRNA), uridines at specific sites ar

211 ng requires 5' splice site recognition by U1 small nuclear RNA (snRNA), which is replaced by U5 and U

212 proximal sequence element that recruits the small nuclear RNA (snRNA)-activating protein complex (SN

213 The small nuclear RNA (snRNA)-activating protein complex (SN

214 The small nuclear RNA (snRNA)-activating protein complex (SN

215 ) protein is essential for the biogenesis of small nuclear RNA (snRNA)-ribonucleoproteins (snRNPs), t

216 it is not involved in transcription from the small nuclear RNA (snRNA)-type, TATA-containing, RNA pol

217 at interact with Saccharomyces cerevisiae U1 small nuclear RNA (snRNA).

218 d adenosine triphosphate, magnesium, and U12 small nuclear RNA (snRNA).

219 teraction that involves base pairing with U2 small nuclear RNA (snRNA).

220 (RRM1) to bind RNA stemloops in U1 and/or U2 small nuclear RNA (snRNA).

221 wn methyltransferase for the U6 spliceosomal small nuclear RNA (snRNA).

222 lysed at a single catalytic metal site in U6 small nuclear RNA (snRNA).

223 y canonical base-pairing to the 5' end of U1 small nuclear RNA (snRNA).

224 Expression of modified U1 small nuclear RNAs (snRNA) complementary to the splice d

225 Small nuclear RNAs (snRNA), cofactors in the splicing of

226 ) hairpins immediately downstream from viral small nuclear RNAs (snRNA).

227 3, +4, and +6) that do not base-pair with U1 small-nuclear RNA (snRNA), the molecule responsible for

228 pecially dependent on a functional U2 snRNP (small nuclear RNA [snRNA] plus associated proteins), as

229 no oligonucleotide [MO] and an engineered U7 small nuclear RNA [snRNA]) to correct this splicing defe

230 Most of the major spliceosomal small nuclear RNAs (snRNAs) (i.e. U1, U2, U4 and U5) are

231 the spliceosome, a complex assembly of five small nuclear RNAs (snRNAs) and a large number of protei

232 , conditional production of 3'-extensions of small nuclear RNAs (snRNAs) and biogenesis of novel tran

233 The 5'-cap structure of most spliceosomal small nuclear RNAs (snRNAs) and certain small nucleolar

234 ear organelles involved in the metabolism of small nuclear RNAs (snRNAs) and histone messages.

235 U small nuclear RNAs (snRNAs) and mRNAs are both transcrib

236 It assembles from five U-rich small nuclear RNAs (snRNAs) and over 200 proteins in a h

237 assembles the heptameric Sm protein core on small nuclear RNAs (snRNAs) and plays a critical role in

238 Small nuclear RNAs (snRNAs) are essential factors in mes

239 In animals, most small nuclear RNAs (snRNAs) are synthesized by RNA polym

240 Most small nuclear RNAs (snRNAs) are synthesized by RNA polym

241 Most small nuclear RNAs (snRNAs) are synthesized by RNA polym

242 Uridine-rich small nuclear RNAs (snRNAs) are the basal components of

243 Because spliceosomal small nuclear RNAs (snRNAs) bind the substrate, snRNA st

244 ng genes requiring RNAPII for transcription, small nuclear RNAs (snRNAs) display a further requiremen

245 risingly, we found that TOE1 associated with small nuclear RNAs (snRNAs) incompletely processed splic

246 osynthesis of U1, U2, U4 and U5 spliceosomal small nuclear RNAs (snRNAs) involves the nuclear export

247 Transcription of genes coding for the small nuclear RNAs (snRNAs) is dependent upon a unique t

248 mRNAs and of precursors to the spliceosomal small nuclear RNAs (snRNAs) is the result of an essentia

249 All small nuclear RNAs (snRNAs) of the [U4/U6.U5] tri-snRNP

250 noRNAs, was identified with the spliceosomal small nuclear RNAs (snRNAs) over 30 years ago, its funct

251 Cross-links identified in the U4 and U6 small nuclear RNAs (snRNAs) suggest U4/U6 stem I as a Br

252 An exception are the small nuclear RNAs (snRNAs) transcribed by RNA polymeras

253 lass of ubiquitously expressed, uridine-rich small nuclear RNAs (snRNAs) transcribed by RNA polymeras

254 ly involves effects of SmD3 on the levels of small nuclear RNAs (snRNAs) U4 and U5.

255 During their biogenesis small nuclear RNAs (snRNAs) undergo multiple covalent mo

256 es at their termini, features reminiscent of small nuclear RNAs (snRNAs) which are abundant and stabl

257 dvantage of our previous observation that U1 small nuclear RNAs (snRNAs) which bind upstream or downs

258 the cytoplasm, precursors to specific tRNAs, small nuclear RNAs (snRNAs), and small nucleolar RNAs (s

259 mitations, we previously proposed the use of small nuclear RNAs (snRNAs), especially U7snRNA to shutt

260 role in melting the duplex between U4 and U6 small nuclear RNAs (snRNAs), leading to the formation of

261 As (miRNAs), small nucleolar RNAs (snoRNAs), small nuclear RNAs (snRNAs), piwi-associated RNAs (piRNA

262 As compared to the metazoan small nuclear RNAs (snRNAs), relatively little is known

263 n tandemly repeated genes encoding U1 and U2 small nuclear RNAs (snRNAs), respectively; the PSU1 locu

264 ssing of a variety of RNAs, including tRNAs, small nuclear RNAs (snRNAs), small nucleolar RNAs (snoRN

265 ection of fluorescently labeled spliceosomal small nuclear RNAs (snRNAs), target the nascent transcri

266 previously unidentified, low-abundance human small nuclear RNAs (snRNAs), U4atac and U6atac, were cha

267 e assembly of heptameric Sm protein rings on small nuclear RNAs (snRNAs), which are essential for snR

268 es (CBs)-subnuclear compartments enriched in small nuclear RNAs (snRNAs)-and promotes efficient splic

269 del comprising 30 proteins plus U4/U6 and U5 small nuclear RNAs (snRNAs).

270 bes genes that encode proteins and noncoding small nuclear RNAs (snRNAs).

271 ins for assembly of Sm cores on the abundant small nuclear RNAs (snRNAs).

272 nscription and processing of RNAPII-mediated small nuclear RNAs (snRNAs).

273 rticipates in the 3' processing of U4 and U5 small nuclear RNAs (snRNAs).

274 te present in four of the major spliceosomal small nuclear RNAs (snRNAs).

275 isruption of 24 base pairs between U4 and U6 small nuclear RNAs (snRNAs).

276 ynamic machine composed of both proteins and small nuclear RNAs (snRNAs).

277 hat the 27-nt repeats could be the source of small nuclear RNA specifically regulating eNOS expressio

278 tain essential spliceosome factors including small nuclear RNAs, splicing proteins, and endogenous pr

279 uired for precursor mRNA splicing through U6 small nuclear RNA stabilization.

280 inhibit the export of both Rev protein and U small nuclear RNAs, suggesting that these nucleoporins p

281 irtually any RNA (e.g., mRNA, ribosomal RNA, small nuclear RNA, telomerase RNA and so on).

282 exon can be prevented by coexpression of U1 small nuclear RNAs, termed shift-U1s, with complementari

283 enzymes and a revised model for CTD-mediated small nuclear RNA termination.

284 th and without the association of 7SK RNA, a small nuclear RNA that is bound to approximately 50% of

285 U85 small CB-specific RNA, U2 small nuclear RNA, the survival of motor neurons protein

286 O-methyl oligonucleotide complementary to U2 small nuclear RNA to study interactions between the UACU

287 transcription factor SNAP(c), which directs small nuclear RNA transcription.

288 rmational rearrangements of the spliceosomal small nuclear RNAs (U snRNAs) are essential for proper a

289 ll known cis-spliceosomal uridylic acid-rich small nuclear RNAs (U snRNAs), suggesting the existence

290 Although uridine-rich small nuclear RNAs (U-snRNAs) are essential for pre-mRNA

291 iking similarities to the cis-spliceosomal U small nuclear RNAs U1, U2, U4 and U5; for example, the S

292 The spliceosomal small nuclear RNAs U1, U2, U4, and U5 are transcribed by

293 Using hairpin II of U1 small nuclear RNA (U1hpII) or the 3' stem loop of histon

294 The auxiliary factor of U2 small nuclear RNA (U2AF) is a heterodimer consisting of

295 promoters (tRNA(Met), tRNA(Val)), the human small nuclear RNA U6 gene (U6) and the adenovirus virus-

296 ound in HEXIM1 immunoprecipitates, while the small nuclear RNAs, U6 and U2, were not.

297 f noncoding RNAs, including the uridine-rich small nuclear RNA (UsnRNA) and enhancer RNA (eRNA), and

298 ffects of the mutants on the synthesis of U5 small nuclear RNA were analyzed.

299 te the suppression of 3' end formation by U1 small nuclear RNA, which is known to bind pre-mRNA at th

300 order to facilitate better association of U1 small nuclear RNA with the intron 5' splice site.