ライフサイエンスコーパス: small nuclear ribonucleoprotein

1 lation site, independent of the U1 snRNP (U1 small nuclear ribonucleoprotein).

2 rs such as Lsm11, a core component of the U7 small nuclear ribonucleoprotein.

3 PRP8 (R1753K), a protein component of the U5 small nuclear ribonucleoprotein.

4 of the 70-kDa subunit of U1 snRNP (U1-70kDa) small nuclear ribonucleoprotein.

5 of the 5' splice site of pre-mRNAs by the U1 small nuclear ribonucleoprotein.

6 ily, interact with the 70k protein of the U1 small nuclear ribonucleoprotein.

7 licing is mediated by the proteins of the U2 small nuclear ribonucleoprotein.

8 ndent conformational change in the intact U2 small nuclear ribonucleoprotein.

9 ding proteins (RBPs): lupus La and 70-kDa U1 small nuclear ribonucleoprotein.

10 which contain mostly nonoverlapping sets of small nuclear ribonucleoproteins.

11 pliceosome type resides in the U6 and U6atac small nuclear ribonucleoproteins.

12 omponent complex involved in the assembly of small nuclear ribonucleoproteins.

13 ated with the Sm core domain of spliceosomal small nuclear ribonucleoproteins.

14 a spliceosome that contains U11, U12, and U5 small nuclear ribonucleoproteins.

15 ex required for the assembly of spliceosomal small nuclear ribonucleoproteins.

16 e complexes with stably bound U2, U5, and U6 small nuclear ribonucleoproteins.

17 that are suppressed, at least in part, by U1 small nuclear ribonucleoproteins.

18 The U1 small nuclear ribonucleoprotein 70-kDa protein, a U1 sma

19 he present study, we characterized U1-70-kDa small nuclear ribonucleoprotein (70-kDa) autoantigen-spe

20 It exists in inactive small nuclear ribonucleoprotein (7SK snRNP) and active (

21 ) kinase, which is suppressed within the 7SK small nuclear ribonucleoprotein (7SK snRNP).

22 To determine whether U1 small nuclear ribonucleoprotein, a multicomponent splici

23 antibodies, including those directed against small nuclear ribonucleoproteins, also arose in CD40L-de

24 ex functions in the assembly of spliceosomal small nuclear ribonucleoproteins and probably other ribo

25 ceosome from analysis of individual purified small nuclear ribonucleoproteins and salt-stable spliceo

26 ort of spliced mRNA, small nuclear RNAs, and small nuclear ribonucleoproteins and slow the nuclear tr

27 uclear domain important to the biogenesis of small nuclear ribonucleoproteins and telomerase, complex

28 nts, FLICE-associated huge protein, Mute, U7 small nuclear ribonucleoprotein, and MPM-2 phosphoepitop

29 ) were found in two other human proteins, U5 small nuclear ribonucleoprotein, and transcription facto

30 globulinemia, autoantibodies against DNA and small nuclear ribonucleoproteins, and immune deposits in

31 erved previously in myelin basic protein, Sm small nuclear ribonucleoproteins, and other polypeptides

32 In contrast, trimethylguanosine-capped small nuclear ribonucleoproteins are predominantly local

33 evidence indicates that U1-70K and other U1 small nuclear ribonucleoproteins are Sarkosyl-insoluble

34 NAs can associate with Sm protein-containing small nuclear ribonucleoproteins, as judged by immunopre

35 ressed in metazoan cells and plays a role in small nuclear ribonucleoprotein assembly and pre-mRNA sp

36 to understand the mechanism of SMN-assisted small nuclear ribonucleoprotein assembly and the underly

37 Here we show that GEMIN2, a spliceosomal small nuclear ribonucleoprotein assembly factor conserve

38 pICln, SMN and Gemin5, which are involved in small nuclear ribonucleoprotein assembly, have an import

39 well characterized function in spliceosomal small nuclear ribonucleoprotein assembly.

40 -COP protein co-immunoprecipitates with SMN, small nuclear ribonucleoprotein-associated assembly fact

41 SFPS colocalizes with U2 small nuclear ribonucleoprotein-associated factors inclu

42 r for plasmid DNA, exon-1 from the imprinted small nuclear ribonucleoprotein-associated polypeptide N

43 Small nuclear ribonucleoprotein-associated polypeptide N

44 at sequential addition of the U4/U6 proteins small nuclear ribonucleoprotein-associated protein 1 (Sn

45 ive, varied immune response against multiple small nuclear ribonucleoprotein autoantigens similar to

46 hanced complex A formation and binding of U2 small nuclear ribonucleoprotein auxiliary factor 65 kDa

47 We reveal that the splicing factor U2 small nuclear ribonucleoprotein auxiliary factor 65-kilo

48 U2AF (U2 small nuclear ribonucleoprotein auxiliary factor) is an

49 eukaryotic pre-mRNA splicing factor U2AF (U2 small nuclear ribonucleoprotein auxiliary factor) is req

50 onucleoprotein polypeptide N), and U2af1 (U2 small nuclear ribonucleoprotein auxiliary factor), remai

51 es assembled on pre-mRNA, blocking U1 snRNP (small nuclear ribonucleoprotein) binding and exon inclus

52 PID in the liberation of P-TEFb from the 7SK small nuclear ribonucleoprotein complex (7SK snPNP).

53 ibitor (PSI) and its interaction with the U1 small nuclear ribonucleoprotein complex (snRNP) control

54 -B, that are physically associated in the U1-small nuclear ribonucleoprotein complex and that are fre

55 rays revealed that serum anti-Smith and anti-small nuclear ribonucleoprotein complex autoantibodies,

56 clin T1 and CDK9 are incorporated in the 7SK small nuclear ribonucleoprotein complex containing the i

57 Its release from the inactive 7SK small nuclear ribonucleoprotein complex is a critical st

58 ncode core components of the spliceosomal U6 small nuclear ribonucleoprotein complex, regulate circad

59 r complexes, or associated with the U4/U6.U5 small nuclear ribonucleoprotein complex.

60 end prior to incorporation into the U4 x U6 small nuclear ribonucleoprotein complex.

61 ltimeric complex involved in the assembly of small nuclear ribonucleoprotein complexes (snRNPs).

62 ckdown of proteins associated with different small nuclear ribonucleoprotein complexes and by using t

63 es are capable of immunoprecipitating native small nuclear ribonucleoprotein complexes.

64 osophila homologue of Prp38p (dPrp38), a tri-small nuclear ribonucleoprotein component, and is requir

65 findings imply that these two genes encoding small nuclear ribonucleoprotein components are subject t

66 tein complex with the methylosome components small nuclear ribonucleoprotein D3b (SmD3b) and protein

67 Brr2 enzyme, which is essential for U4/U6 di-small nuclear ribonucleoprotein disruption during splice

68 ntial role in the biogenesis of spliceosomal small nuclear ribonucleoproteins in all tissues.

69 cts with several Sm proteins of spliceosomal small nuclear ribonucleoproteins, in particular, with Sm

70 The U1 and U11 small nuclear ribonucleoproteins interact with sequences

71 erlying the conversion of soluble nuclear U1 small nuclear ribonucleoproteins into insoluble cytoplas

72 mammalian 70K protein, a component of the U1 small nuclear ribonucleoprotein involved in pre-mRNA spl

73 The U6 small nuclear ribonucleoprotein is a critical component

74 proteins found in the U1 and U2 spliceosomal small nuclear ribonucleoproteins is highly conserved.

75 ts some novel functions for Snp1p and the U1 small nuclear ribonucleoprotein late in spliceosome deve

76 of PWS carrying a paternal (p) deletion from small nuclear ribonucleoprotein N (Snrpn (S)) to ubiquit

77 n, t(15;19)(q12;q13.41), which disrupted the small nuclear ribonucleoprotein N (SNRPN) locus.

78 and humans, the locus encoding the gene for small nuclear ribonucleoprotein N (SNRPN/Snrpn), as well

79 tends approximately 450 kb to UBE3A from the small nuclear ribonucleoprotein N (SNURF/SNRPN) promoter

80 otein that is found in the U1 and U2 snRNPs (small nuclear ribonucleoproteins) of Drosophila.

81 e 3' splice site and promotes assembly of U2 small nuclear ribonucleoprotein on the upstream branch p

82 x, SF3B3 and SF3B5, that form part of the U2 small nuclear ribonucleoprotein particle (snRNP) are als

83 The mobile U2 small nuclear ribonucleoprotein particle (snRNP) associa

84 snRNP and the polypyrimidine tract by the U2 small nuclear ribonucleoprotein particle (snRNP) auxilia

85 The U2 small nuclear ribonucleoprotein particle (snRNP) auxilia

86 Prp24 is a component of the free U6 small nuclear ribonucleoprotein particle (snRNP) but not

87 he 5' splice site, and a component of the U2 small nuclear ribonucleoprotein particle (snRNP) complex

88 k9-cyclin T modules from large, inactive 7SK small nuclear ribonucleoprotein particle (snRNP) complex

89 In this investigation, we made use of anti-small nuclear ribonucleoprotein particle (snRNP) Ig tran

90 The current model for the function of the U5 small nuclear ribonucleoprotein particle (snRNP) in the

91 t dephosphorylated SRp38 interacts with a U1 small nuclear ribonucleoprotein particle (snRNP) protein

92 s shown to promote the recruitment of the U1 small nuclear ribonucleoprotein particle (snRNP) to the

93 This requires the interaction of the U7 small nuclear ribonucleoprotein particle (snRNP) with a

94 Previous work demonstrated that U1 small nuclear ribonucleoprotein particle (snRNP), bound

95 Coiled bodies also contain the U7 small nuclear ribonucleoprotein particle (snRNP), which

96 odes a protein factor that contributes to U1 small nuclear ribonucleoprotein particle (snRNP)-pre-mRN

97 r RNA (pre-mRNA) splicing, as part of the U1 small nuclear ribonucleoprotein particle (snRNP).

98 early intron recognition factors U2AF and U1 small nuclear ribonucleoprotein particle (snRNP).

99 The U1 small nuclear ribonucleoprotein particle (U1 snRNP) 70K

100 The product of the U1 small nuclear ribonucleoprotein particle (U1 snRNP) 70K

101 ) domain of spliceosomal A protein of the U1 small nuclear ribonucleoprotein particle (U1A) interacti

102 The pre-mRNA splicing factor U2AF (U2 small nuclear ribonucleoprotein particle [snRNP] auxilia

103 was detected in association with a subset of small nuclear ribonucleoprotein particle and Ser-Arg pro

104 esidues 885-2413) in complex with Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor

105 This focused attention on the U2 small nuclear ribonucleoprotein particle auxiliary splic

106 Targeting a lupus autoantigen, the small nuclear ribonucleoprotein particle D protein, to t

107 and trans-splicing using the specialized SL2 small nuclear ribonucleoprotein particle for downstream

108 thereby promoting the dissociation of the U1 small nuclear ribonucleoprotein particle from the 5' spl

109 hat SmD1, a core component of the Drosophila small nuclear ribonucleoprotein particle implicated in s

110 40, indicating that Prp40 is bound to the U1 small nuclear ribonucleoprotein particle in vivo.

111 the 5' splice site, cross-linking of the U5 small nuclear ribonucleoprotein particle protein, U5(200

112 been shown to encode a Drosophila U1 and U2 small nuclear ribonucleoprotein particle protein.

113 ates that these complexes contain additional small nuclear ribonucleoprotein particle proteins and th

114 l nuclear ribonucleoprotein (snRNP) is a 25S small nuclear ribonucleoprotein particle similar in size

115 The U1 small nuclear ribonucleoprotein particle U1C protein has

116 which facilitates the interaction of the U2 small nuclear ribonucleoprotein particle with the branch

117 ceosome assembly within the mature U2 snRNP (small nuclear ribonucleoprotein particle), and its displ

118 Prp8, a component of the U5 small nuclear ribonucleoprotein particle, crosslinks ext

119 The A protein of the U1 small nuclear ribonucleoprotein particle, interacting wi

120 ose) polymerase, the 70-kD protein of the U1 small nuclear ribonucleoprotein particle, lamin B, the n

121 IIF (TFIIF), TFIIS, splicing factors, the U7 small nuclear ribonucleoprotein particle, the stem-loop

122 nd in a manner independent of Prp16p, the U5 small nuclear ribonucleoprotein particle-associated prot

123 component that associates with the yeast U1 small nuclear ribonucleoprotein particle.

124 icing in C. merolae may occur without the U1 small nuclear ribonucleoprotein particle.

125 -B7.2 Abs expressed significantly lower anti-small nuclear ribonucleoprotein particles (snRNP) and an

126 of these introns requires a different set of small nuclear ribonucleoprotein particles (snRNPs) (U11,

127 When Prp24 is absent, unpaired U4 and U6 small nuclear ribonucleoprotein particles (snRNPs) accum

128 functions in the biogenesis of spliceosomal small nuclear ribonucleoprotein particles (snRNPs) and p

129 The U1, U2, U4, U5 and U6 small nuclear ribonucleoprotein particles (snRNPs) are e

130 The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) invol

131 site for the Sm proteins, both hallmarks of small nuclear ribonucleoprotein particles (snRNPs) that

132 cipitation (ChIP) analysis of U1, U2, and U5 small nuclear ribonucleoprotein particles (snRNPs) to in

133 e interactions between the five spliceosomal small nuclear ribonucleoprotein particles (snRNPs) U1, U

134 r messenger RNA substrate bound to U1 and U2 small nuclear ribonucleoprotein particles (snRNPs), and

135 Sm proteins form the core of small nuclear ribonucleoprotein particles (snRNPs), maki

136 tion as an assembly machine for spliceosomal small nuclear ribonucleoprotein particles (snRNPs), the

137 Human spliceosomal U1 small nuclear ribonucleoprotein particles (snRNPs), whic

138 a complex that functions in the assembly of small nuclear ribonucleoprotein particles (snRNPs).

139 B" and is an integral component of U1 and U2 small nuclear ribonucleoprotein particles (snRNPs).

140 mplex containing U1, U2, U5 and duplex U4/U6 small nuclear ribonucleoprotein particles (snRNPs).

141 nucleotides, a method that was developed for small nuclear ribonucleoprotein particles (snRNPs).

142 organization of antigens associated with the small nuclear ribonucleoprotein particles (snRNPs).

143 by the spliceosome, a complex of five major small nuclear ribonucleoprotein particles (snRNPs).

144 of Sm core structures of spliceosomal U-rich small nuclear ribonucleoprotein particles (UsnRNPs) requ

145 strictive temperature (39.5 degrees C), both small nuclear ribonucleoprotein particles and a general

146 ke proteins are stable components of several small nuclear ribonucleoprotein particles that function

147 autoreactive B cells that recognize self-Ag small nuclear ribonucleoprotein particles with activated

148 important for the biogenesis of spliceosomal small nuclear ribonucleoprotein particles, but downstrea

149 tion occurred after inactivation of U1 or U2 small nuclear ribonucleoprotein particles, compatible wi

150 d the spliceosome, which is composed of five small nuclear ribonucleoprotein particles, U1, U2, U4/U6

151 Prp18 forms a bridge between Slu7 and the U5 small nuclear ribonucleoprotein particles.

152 o alpha-helices and may interact with the U5 small nuclear ribonucleoprotein particles.

153 l microdeletions within the 5' region of the small nuclear ribonucleoprotein polypeptide N ( SNRPN )

154 The gene for the small nuclear ribonucleoprotein polypeptide N (SNRPN) is

155 bserved at maternally methylated ICs such as small nuclear ribonucleoprotein polypeptide N (SNRPN), S

156 The human SNRPN (small nuclear ribonucleoprotein polypeptide N) gene is o

157 nscript), Sgce (epsilon-sarcoglycan), Snrpn (small nuclear ribonucleoprotein polypeptide N), and U2af

158 3), insulin-like growth factor 2 (IGF2), and small nuclear ribonucleoprotein polypeptide N, and the l

159 mplicated in the biogenesis of several other small nuclear ribonucleoproteins required for processing

160 nting stable recruitment of the U4/U5/U6 tri-small nuclear ribonucleoprotein, resulting in accumulati

161 rs include histone, a protein component of a small nuclear ribonucleoprotein, ribosomal proteins, and

162 aled that these structures contained the non-small nuclear ribonucleoprotein RNA processing factor, S

163 We show that newly assembled small nuclear ribonucleoprotein (RNP [snRNP]) particles,

164 he CB, such as the SMN complex, spliceosomal small nuclear ribonucleoproteins (RNPs), small nucleolar

165 l domain has a protein fold similar to human small nuclear ribonucleoprotein Sm D3 and Haloarcula mar

166 ted with B7 blocking Abs exhibit strong anti-small nuclear ribonucleoprotein (snRNP) and anti-DNA aut

167 splicing pathway through association with U1 small nuclear ribonucleoprotein (snRNP) and non-snRNP sp

168 duction, as seen in serum Ig, anti-DNA, anti-small nuclear ribonucleoprotein (snRNP) and rheumatoid f

169 pathway and involves interactions between U1 small nuclear ribonucleoprotein (snRNP) and the pre-mRNA

170 The SMN protein is important in small nuclear ribonucleoprotein (snRNP) assembly and int

171 which were associated with an improvement in small nuclear ribonucleoprotein (snRNP) assembly.

172 compared with SMN likely leading to loss of small nuclear ribonucleoprotein (snRNP) assembly.

173 esting an unknown quality control system for small nuclear ribonucleoprotein (snRNP) assembly.

174 SMN is critical for small nuclear ribonucleoprotein (snRNP) assembly.

175 We previously showed that U1 small nuclear ribonucleoprotein (snRNP) associates with

176 RE consists of a single 9-nucleotide (nt) U1 small nuclear ribonucleoprotein (snRNP) base pairing sit

177 Definition occurs by U1 small nuclear ribonucleoprotein (snRNP) binding the 5' S

178 class 5' splice site and is required for U11 small nuclear ribonucleoprotein (snRNP) binding to the N

179 and Gemin4, and it plays important roles in small nuclear ribonucleoprotein (snRNP) biogenesis and i

180 N has been shown to function in spliceosomal small nuclear ribonucleoprotein (snRNP) biogenesis and p

181 tein plays an important role in spliceosomal small nuclear ribonucleoprotein (snRNP) biogenesis and t

182 U6 small nuclear ribonucleoprotein (snRNP) biogenesis is es

183 urney to the spliceosome.The mechanism of U6 small nuclear ribonucleoprotein (snRNP) biogenesis is no

184 SMN functions in small nuclear ribonucleoprotein (snRNP) biogenesis, but

185 s (CBs) are subnuclear domains implicated in small nuclear ribonucleoprotein (snRNP) biogenesis.

186 Nuclear import is an essential step in small nuclear ribonucleoprotein (snRNP) biogenesis.

187 trates within Cajal bodies (CBs) and impacts small nuclear ribonucleoprotein (snRNP) biogenesis.

188 stered into a transcriptionally inactive 7SK small nuclear ribonucleoprotein (snRNP) by the coordinat

189 Interestingly, canonical CB foci and coilin/small nuclear ribonucleoprotein (snRNP) co-localization

190 Sera known to recognize the U1-small nuclear ribonucleoprotein (snRNP) complex (confirm

191 eoli and bound what we believe to be a novel small nuclear ribonucleoprotein (snRNP) complex composed

192 Autoantibody response against the small nuclear ribonucleoprotein (snRNP) complex is a cha

193 binds 7SK RNA and, as a component of the 7SK small nuclear ribonucleoprotein (snRNP) complex, is recr

194 atalytically inactive state bound to the 7SK small nuclear ribonucleoprotein (snRNP) complex.

195 ol II) once released from the inhibitory 7SK small nuclear ribonucleoprotein (snRNP) complex.

196 se mice do not develop autoantibodies to the small nuclear ribonucleoprotein (snRNP) complex.

197 ) complex is essential for the biogenesis of small nuclear ribonucleoprotein (snRNP) complexes in euk

198 many splicing factors, including the key U2 small nuclear ribonucleoprotein (snRNP) component SF3B1

199 spliceostatin A, sudemycin E binds to the U2 small nuclear ribonucleoprotein (snRNP) component SF3B1.

200 The small nuclear ribonucleoprotein (snRNP) core domain, act

201 otor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles.

202 Pre-mRNA binding to the yeast U2 small nuclear ribonucleoprotein (snRNP) during presplice

203 In eukaryotes, U1 small nuclear ribonucleoprotein (snRNP) forms spliceosom

204 The yeast U4/U6.U5 pre-mRNA splicing small nuclear ribonucleoprotein (snRNP) is a 25S small n

205 The initial steps of spliceosomal small nuclear ribonucleoprotein (snRNP) maturation take

206 U1 small nuclear ribonucleoprotein (snRNP) may function dur

207 8p is a unique component of the U4/U6.U5 tri-small nuclear ribonucleoprotein (snRNP) particle and is

208 association of PSI with the spliceosomal U1 small nuclear ribonucleoprotein (snRNP) particle in soma

209 thway of subunit addition that includes both small nuclear ribonucleoprotein (snRNP) particles and no

210 In addition to La and Ro52, proteins in the small nuclear ribonucleoprotein (snRNP) particles such a

211 ous nuclear ribonucleoproteins (hnRNPs), and small nuclear ribonucleoprotein (snRNP) particles throug

212 The 7SK small nuclear ribonucleoprotein (snRNP) plays a central

213 novo motif analysis shows PAS signals and U1 small nuclear ribonucleoprotein (snRNP) recognition site

214 The 7SK small nuclear ribonucleoprotein (snRNP) sequesters and i

215 ing protein 1, and with several spliceosomal small nuclear ribonucleoprotein (snRNP) Sm proteins.

216 Stable addition of U2 small nuclear ribonucleoprotein (snRNP) to form the pres

217 ds to exon 3 of the pre-mRNA and recruits U1 small nuclear ribonucleoprotein (snRNP) to the F1 pseudo

218 The Ul small nuclear ribonucleoprotein (snRNP), a complex of ni

219 nisms that regulate P-TEFb involving the 7SK small nuclear ribonucleoprotein (snRNP), factors that co

220 splicing factor compartment (SFC) [e.g. the small nuclear ribonucleoprotein (snRNP), U2B, and serine

221 p80-coilin, which is colocalized with the U7 small nuclear ribonucleoprotein (snRNP), whereas the att

222 is inhibited by HEXIM1 or HEXIM2 in the 7SK small nuclear ribonucleoprotein (snRNP), which contains,

223 m a duplex formed with the low abundance U12 small nuclear ribonucleoprotein (snRNP), which we confir

224 U1 small nuclear ribonucleoprotein (snRNP)-70K (U1-70K), a

225 ctions of individual SR proteins with the U1 small nuclear ribonucleoprotein (snRNP)-associated 70-kD

226 In Caenorhabditis elegans, the small nuclear ribonucleoprotein (snRNP)-associated prote

227 Both the BBR and BPS interact with the U2 small nuclear ribonucleoprotein (snRNP)-associated SF3b

228 U1C is one of the three human U1 small nuclear ribonucleoprotein (snRNP)-specific protein

229 loop by an endonuclease dependent on the U7 small nuclear ribonucleoprotein (snRNP).

230 eins or release P-TEFb from the inactive 7SK small nuclear ribonucleoprotein (snRNP).

231 ylating the RNA, likely by competing with U1 small nuclear ribonucleoprotein (snRNP).

232 functions only if it is assembled into an Sm small nuclear ribonucleoprotein (snRNP).

233 a regions, with those from autoantibodies to small nuclear ribonucleoproteins (snRNP).

234 spliceosome is a complex machine composed of small nuclear ribonucleoproteins (snRNPs) and accessory

235 olyadenylation and was recognized by both U1 small nuclear ribonucleoproteins (snRNPs) and alternativ

236 clear organelles that are highly enriched in small nuclear ribonucleoproteins (snRNPs) and certain ba

237 ntial role in the production of spliceosomal small nuclear ribonucleoproteins (snRNPs) and likely oth

238 mportant role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs) and likely oth

239 dynamic RNA-protein machinery consisting of small nuclear ribonucleoproteins (snRNPs) and non-snRNP

240 a key role in the biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) and other ribo

241 nslational modification in the biogenesis of small nuclear ribonucleoproteins (snRNPs) and pre-mRNA s

242 s a role in the assembly and regeneration of small nuclear ribonucleoproteins (snRNPs) and spliceosom

243 Small nuclear ribonucleoproteins (snRNPs) are core compo

244 rine-arginine (SR) proteins, U1snRNP, and U6 small nuclear ribonucleoproteins (snRNPs) are implicated

245 tterns of autoantibody reactivities with the small nuclear ribonucleoproteins (snRNPs) are observed i

246 essential for the biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) as it binds to

247 splicing factors SF2/ASF and U1, U2, and U11 small nuclear ribonucleoproteins (snRNPs) bind the NRS,

248 The U1, U2, U4, U5, and U6 small nuclear ribonucleoproteins (snRNPs) form essential

249 d are associated with defects in assembly of small nuclear ribonucleoproteins (snRNPs) in vitro.

250 The spliceosomal U small nuclear ribonucleoproteins (snRNPs) interact with

251 5), which are required for the biogenesis of small nuclear ribonucleoproteins (snRNPs) involved in mR

252 Cytoplasmic assembly of Sm-class small nuclear ribonucleoproteins (snRNPs) is a central p

253 The assembly of metazoan Sm-class small nuclear ribonucleoproteins (snRNPs) is an elaborat

254 machinery including SR proteins, U1 and U2, small nuclear ribonucleoproteins (snRNPs) of the major s

255 sequential recruitment and rearrangement of small nuclear ribonucleoproteins (snRNPs) on a pre-mRNA

256 rected cross-linking with in vitro assembled small nuclear ribonucleoproteins (snRNPs) or spliceosome

257 lear domains important for the biogenesis of small nuclear ribonucleoproteins (snRNPs) which function

258 ct with the Sm core proteins of spliceosomal small nuclear ribonucleoproteins (snRNPs), and they play

259 onents of the spliceosome, U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), contain seven

260 ing production of IgG autoantibodies against small nuclear ribonucleoproteins (snRNPs), dsDNA, and se

261 Because MAH does not bind small nuclear ribonucleoproteins (snRNPs), it appears to

262 N complex is essential for the biogenesis of small nuclear ribonucleoproteins (snRNPs), the major con

263 cle, the spliceosome which contains the five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U

264 Small nuclear ribonucleoproteins (snRNPs), which are ess

265 E, F, and G, shared by U1, U2, U4-6, and U5 small nuclear ribonucleoproteins (snRNPs), while anti-nu

266 at functions in the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs).

267 x required for biogenesis of the Sm class of small nuclear ribonucleoproteins (snRNPs).

268 x that is required for biogenesis of various small nuclear ribonucleoproteins (snRNPs).

269 olism that accumulate high concentrations of small nuclear ribonucleoproteins (snRNPs).

270 suborganelles involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs).

271 on of SMN is as an assembler of spliceosomal small nuclear ribonucleoproteins (snRNPs).

272 splicing, forming the cores of spliceosomal small nuclear ribonucleoproteins (snRNPs).

273 The human small nuclear ribonucleoprotein SNRPB ' /B gene is alter

274 clear ribonucleoprotein 70-kDa protein, a U1 small nuclear ribonucleoprotein-specific protein, has be

275 re we report that U1C, one of three human U1 small nuclear ribonucleoprotein-specific proteins, inter

276 d with an antibody to SC35, an essential non-small nuclear ribonucleoprotein splicing factor.

277 ormation of aberrant U11- and U12-containing small nuclear ribonucleoproteins that impair the efficie

278 mic acid, which releases P-TEFb from the 7SK small nuclear ribonucleoprotein, they turned green.

279 intron polypyrimidine tract and recruits U2 small nuclear ribonucleoprotein to the branch site.

280 as a base-paired complex within the U4/U6.U5 small nuclear ribonucleoprotein (tri-snRNP).

281 in the assembly of spliceosomal uridine-rich small nuclear ribonucleoprotein (U snRNP) complexes coul

282 Uridine-rich small nuclear ribonucleoproteins (U snRNPs) are involved

283 for novel peptide sequences in either p53 or small nuclear ribonucleoprotein-U (snRNP-U) and substant

284 R proteins but does not interact with the U1 small nuclear ribonucleoprotein U1-70K or the 35-kDa sub

285 he early spliceosome assembly begins with U1 small nuclear ribonucleoprotein (U1 snRNP) binding to th

286 n the disease, including U1-70K and other U1 small nuclear ribonucleoprotein (U1 snRNP) spliceosome c

287 the U1 small nuclear RNA component of the U1 small nuclear ribonucleoprotein (U1 snRNP) splicing fact

288 components of the spliceosomal subcomplex U1 small nuclear ribonucleoprotein (U1 snRNP).

289 ng factors (SR splicing factors) with the U1-small nuclear ribonucleoprotein (U1-snRNP) and U3-small

290 The U1-small nuclear ribonucleoprotein (U1-snRNP) that includes

291 Binding of U1 small nuclear ribonucleoprotein (U1snRNP) to DM20 is gre

292 me proteins associated with the uridine-rich small nuclear ribonucleoproteins U2, U5, and U6 and the

293 SF3B1), a key spliceosomal protein of the U2 small nuclear ribonucleoprotein (U2 snRNP).

294 The auxiliary factor of U2 small nuclear ribonucleoprotein (U2AF) facilitates branc

295 g in mammalian cell extracts requires the U7 small nuclear ribonucleoprotein (U7 snRNP) and an uniden

296 The U1A/U2B''/SNF family of small nuclear ribonucleoproteins uses a phylogenetically

297 bly of RNA-protein complexes of uridine-rich small nuclear ribonucleoproteins (UsnRNPs).

298 the latter, it is incorporated into the 7SK small nuclear ribonucleoprotein, which contains hexameth