ライフサイエンスコーパス: so many

1 eventing a disease that touches the lives of so many.

2 xoribonucleases, raising the question of why so many activities are present in the complex.

3 le reason why a single drug is indicated for so many age-related diseases is that it inhibits the agi

4 With so many agents available for the treatment of indolent l

5 H) are distinct, but converge when there are so many alleles that traits fluctuate close to their exp

6 f the tendency of this disease to present in so many and diverse patterns.

7 ed activated in a number of cancers in which so many antagonists are surrounded.

8 osmolarity, but we lack explanations for why so many antiporters are needed and for the value added b

9 Furthermore, the availability of so many approved treatments raises questions about the e

10 However, as in so many areas of molecular biology, the advent of archae

11 chemical science and for its applications in so many aspects of everyday life.

12 ht on the mechanisms that have given rise to so many bacterial and viral ORFans.

13 nly a short period during the lytic cascade, so many cells with HHV-8 in the lytic phase responded to

14 st a possible structural explanation for how so many commonly used medications block HERG but not oth

15 Why do brains have so many connections?

16 known about why insulin resistance occurs in so many contexts.

17 ediate states and accounts for why there are so many controversies about intermediates versus compact

18 ding its role in cell biology: why are there so many copies of Ter, why are they distributed over suc

19 amily evolution and clues about the need for so many CPR genes.

20 Current mapping algorithms cannot handle so many data without building hierarchies of framework m

21 The role of ethylene in so many deficiencies suggests that, to confer specificit

22 How does auxin affect so many different aspects of plant growth and developmen

23 gs that identify a single reliable change in so many different cancers.

24 h identical DNA sequences differentiate into so many different cell types.

25 consistency between mass balance results on so many different days and in two different seasons, ena

26 nations of transcription factors can silence so many different donor programs.

27 g question of how a single gene can manifest so many different effects.

28 for the ability of HNP-1 to HNP-3 to inhibit so many different exotoxins is proposed.

29 taxias suggest a rational hypothesis for how so many different genes lead to predominantly cerebellar

30 However, there are so many different hydrogen bonding patterns that a descr

31 tly been incriminated, and it is unclear how so many different infections may play a role.

32 The fact that APC is an integral part of so many different pathways makes it an ideal target for

33 The fact that so many different primary transforming events give rise

34 this small domain play such a large role for so many different proteins?

35 training regimen may induce improvements in so many different skills is notable because the majority

36 l surface receptors which allow infection of so many different species and cell types are still incom

37 y explain why trait exaggeration has evolved so many different times in the context of sexual selecti

38 eries of neuroscience is why neurons express so many different types of ion channels with such wide-r

39 tools that helped the discipline develop in so many different ways began to appear in the late thirt

40 oubled by a technology that causes Europeans so many difficulties?

41 volve high affinity, selective receptors for so many distinct chemical structures.

42 asts, chemoreceptors), but perhaps none show so many distinct patterns in terms of number and localiz

43 n a single lipid in a fluid bilayer regulate so many distinct physiological processes?

44 The concordance of this defect among so many diverse autoimmune-prone strains suggests that t

45 our knowledge, this is the first case where so many diverse morphologic forms were manifested in a s

46 Because PP2A is involved in so many diverse processes, it is highly regulated by bot

47 roblem of how a master regulator can control so many diverse receptors.

48 the reasons that might justify the need for so many DNA polymerases, describe their function and mod

49 itration of any soluble reductants involving so many electrons.

50 It is not clear why so many extracellular domains need to be evolved through

51 Thus, unlike so many facets of modern cardiovascular practice and CAD

52 nally progressed beyond phase 2 trials after so many failures on other targets.

53 ILC1s are developmentally distinct but share so many features that they are difficult to distinguish,

54 fundamental process and has been studied by so many for so long that skeptics might ask what more th

55 However, the question remains why so many functional domains cluster together in one relat

56 How this single motor protein performs so many functions has remained a major outstanding quest

57 hy nature endowed this specific protein with so many functions may remain a mystery.

58 n important issue in parametric modeling for so many gene expression levels is the control of the num

59 onent, not least of which is why plants have so many genes for the cellulose synthase catalytic subun

60 es, raises the question of why bacteria need so many GGDEF enzymes.

61 The presence of so many highly related signaling proteins in individual

62 ilure to focus efforts on the IFIs that kill so many HIV patients has led to fundamental flaws in the

63 How it avoids innate immune defenses in so many hosts is not understood.

64 ndard Rapid Response Team activation and did so many hours in advance.

65 The two chlorine dioxide treatments each had so many HPC counts of 0 that a meaningful statistical di

66 o predict how a law of such complexity, with so many human variables, will work out in the end.

67 one reason for the conservation of Ile51 in so many Ig VH.

68 euroscientists because it is associated with so many important cognitive functions.

69 r terrestrial genus of animals has sponsored so many independent aquatic invasions, and no other inse

70 w to appropriately care for, and respond to, so many individuals and families coping with the exigenc

71 Because so many individuals die from starvation, disease and pre

72 We are grateful to have received so many insightful commentaries from interested colleagu

73 With so many interesting papers presented, it is impossible t

74 se I did not expect that varphi29 would give so many interesting results, but I worked hard, with a l

75 The late Pleistocene extinction of so many large-bodied vertebrates has been variously attr

76 The observation of so many long-range interactions in a small, rigid system

77 rt period variability values between groups, so many LSI patients could be incorrectly classified as

78 How and why so many materials choose dramatic non-crystallographic d

79 ght to understand why gestating parents have so many mates and such high incidences of successful mul

80 ental variables that follow a random walk or so many mechanisms were affecting these variables, in di

81 Even so, many medical school-based radiology departments have

82 in phospholipid structure and why there are so many membrane lipids.

83 oduce syndromes like bipolar disorder or why so many mental illnesses co-occur together.

84 Actually, during the last two decades or so, many methods in this regard have been established in

85 microbial recovery yet the real reasons why so many microbes do not grow on artificial media remain

86 e in transendothelial migration and asks why so many molecules seem to be involved.

87 It is unclear why there are so many more neurons in sensory cortex than in the senso

88 out the same number of genes as mice and not so many more than worm, what makes us more complex?

89 to origins, providing an explanation for why so many mutants in DNA replication show checkpoint defec

90 career path are seen as being outweighed by so many negative factors, as to prompt the question, "Is

91 nature of this network helps to explain why so many neurological conditions produce dysphagia.

92 pled receptors will lead to the discovery of so many new neuropeptides that it may well double their

93 The finding of so many new plant viruses that do not cause any obvious

94 e two routes to exaggeration and suggest why so many of the most exaggerated insect structures scale

95 auto-catalytic and cross-catalytic nature of so many of the putative processes associated with self-r

96 Our extraordinary ability to retrieve so many of them at a later time is due in no small part

97 cterizing RXLR-EER effectors and discuss why so many of these rapidly evolving proteins are encoded b

98 of free integrins on the cell surface since so many of these receptors are bound to the surface liga

99 m may explain why they are still retained in so many organisms.

100 diseases is its ability to infect and affect so many other family members, not just the child.

101 laser that is not specific to the molecule, so many other molecular ions, including polyatomic speci

102 man and environmental health for which, like so many other small molecules, no suitable biorecognitio

103 transport of tubulin has eluded detection in so many other studies.

104 My path, like those of so many others, had too many idiosyncratic twists and tu

105 ing the 1950s, and his influence on me-as on so many others-has persisted ever since.

106 termed 2-oxoglutarate) as a co-substrate in so many oxidation reactions throughout much of nature is

107 Most importantly, because so many parents are unaware of the potential risk of ina

108 hat we call "the macrophage paradox:" why do so many pathogenic bacteria replicate in the very cells

109 question of why vitamin A deficiency causes so many pathologies that are independent of retinoic aci

110 A question is why, with so many people consuming contaminated raw oysters, the i

111 But so many people, especially younger scientists, want to k

112 it would not be possible to sustain herds if so many pocket Bibles were produced from fetal skins, ar

113 Biological networks have so many possible states that exhaustive sampling is impo

114 Never before have so many potential targets been studied.

115 Why so many precursor types are needed to produce neurons ha

116 Because of the importance of tarsiers in so many primatological problems, there has been particul

117 iding translational research is fraught with so many problems that the validity of research conclusio

118 Why does calcium have so many regulatory functions?

119 With so many research groups generating their own data, the a

120 A broader goal is to illustrate why so many researchers are enthusiastic about the SEM appro

121 ible for the oceanic anoxia that has puzzled so many researchers for so many years.

122 As so many sepsis survivors succumb later to persistent, re

123 nalities of a replicase complex in producing so many sgRNAs, we examined initiating nucleotides of th

124 cations for how such a tiny protein can send so many signals.

125 The discrepancies between so many simulations and subsequent experimental testing

126 sources and to dominate them may explain how so many species apparently dependent on similar resource

127 some groups of organisms, like beetles, have so many species, and others, like the tuataras, so few?

128 his apparently ubiquitous system to initiate so many specific and appropriate end responses.

129 seful in disease association studies because so many STR elements manifest multiallelic polymorphism.

130 It is unclear why so many structurally diverse compounds block HERG channe

131 osed motion of IgE-Fc(3-4) was possible with so many structures, and the new structures allow a more

132 size 2-5(A), the reason for the existence of so many synthetase isozymes is unclear.

133 Because cI is used in so many synthetic biology projects, the new set of varia

134 With so many therapeutic options in sight and the ongoing elu

135 Why are there so many transmitters?

136 undation for the cognitive modeling embodies so many underlying implications that the subject is far

137 are more computationally costly and may have so many unknown parameters that their results are not as

138 sons provided clues toward understanding how so many variants of these multigenic loci could have evo

139 elucidate how bats serve as a reservoir for so many viruses.

140 lable for both these common cancers, yet for so many women access to these is beyond reach.

141 One might wonder after so many years of detailed poking at such a seemingly sim

142 xia that has puzzled so many researchers for so many years.

143 r biological functions, have been hidden for so many years.

144 ains 13 ZFs, but it is unknown why Miz-1 has so many ZFs and whether they recognize and bind DNA sequ