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1 e article and the article is being withdrawn so that a corrected manuscript can be submitted for publ
2 s with a relatively low identity requirement so that a long read region can be aligned to at least on
3 ghly efficient Cas9-directed genome editing, so that a parental line can be expeditiously engineered
4     This heterogeneity needs to be evaluated so that a personalized management approach can be provid
5 c input range into its limited output range, so that a signal is neither buried in noise in darkness
6 r the reaction is conducted intramolecularly so that a specific C-H bond is favoured.
7 d that is encoded by two disjoint codon sets so that a tandem substitution of two nucleotides is requ
8 ombat newly arising influenza virus strains, so that a universal vaccine is highly desirable.
9                                      So much so, that a general method for the direct asymmetric alky
10 uations, these conditions are not fulfilled, so that accumulations with time are nonlinear.
11 oward and behavior regarding climate change, so that across these studies conservatives and liberals
12 ike state, poxviruses remodel host ribosomes so that adenosine repeats erroneously generated by slipp
13 and how long the duration of ischemia can be so that adjunct cardioprotection by postconditioning at
14 11 levels also detected many other molecules so that age-dependent changes in GDF11 are still not wel
15 dels genome-wide patterns of DNA methylation so that age-related changes are profoundly delayed, whil
16  of clinical presentations of ZIKV infection so that agents to prevent and treat this devastating dis
17 selection, data export and R code generation so that all analyses are reproducible.
18 on nanoscale polymer brushes on glass chips, so that all reagents are "on-chip," and these chips show
19 at potential to be repurposed as antibiotics so that an old drug can learn new tricks.
20 tegy, where HIV transcription is reactivated so that antiretroviral therapy and the immune system cle
21 tuting nodes for each input node in the MIS, so that any node in the set can replace the latter.
22 after completion of cancer-directed therapy, so that appropriate interventions can be initiated to ha
23 ntial loss to follow-up should be considered so that appropriate statistical methods can be incorpora
24 ly expose the alpha-arrestin-targeted region so that Art1 activation via TORC1 is sufficient to trigg
25  is proposed to direct the stochastic search so that, as a result of the randomly generated associati
26 251 from salt bridges with Arg186 and Lys178 so that Asp251 can participate in a proton relay network
27 r neural activity patterns to similar odors, so that behaviors learned from one odor can be applied w
28 ally exposes myosin binding sites on F-actin so that binding of rigor myosin is required to fully act
29  prepared as a fusion to the relevant enzyme so that binding of the receptor to the immobilized ligan
30  Psychological well-being improved over time so that both groups of women eventually converged.
31  of multiferroic phases develop subsequently so that both large polarization and significant magnetoe
32  one postnatal month and declines thereafter so that by about 3 months of age MD has little effect.
33 n, serum cystatin C and creatinine diverged, so that by ICU discharge, almost twice as many patients
34 ecessary to ensure sufficient Akt activation so that cancer cells are able to grow under anchorage-in
35 NH and these hearing-impaired (HI) listeners so that central effects in multisource listening can be
36 tratospheric ozone returns to normal levels, so that climate conditions conducive to widespread fire
37 es must be characterized and planned for now so that clinical trials can progress expediently and eff
38 e the data required for the planned analyses so that combined with low event rates for some important
39 ton energy exceeds the electronic bandwidth, so that completely filled or completely empty bands must
40 favour some, and suppress other, transitions so that completion of a mechanical cycle in a direction
41 derscores that LOI phenotypes are multigenic so that complex interactions will contribute to disease
42 e set up to perform focused library screens, so that compound labeling is not required anymore.
43 need for careful modelling of nonlinearities so that conclusions are not driven by unrecognised model
44 submission of identified substrate cleavages so that conservation of the cleavage site can be assesse
45 ic real-time assessment of tumor vascularity so that contrast enhancement can be identified regardles
46 ion evolves under a wide range of conditions so that cooperation becomes "instinctive." Norm internal
47  haploidy was shown to be an unstable state, so that cultures of mammalian haploid cells rapidly beco
48 cation of electrical biosensors with BD-UNCD so that dielectrophoretic preconcentration can be perfor
49 nces in patient populations across providers so that differences in outcomes are truly attributable t
50 seudo-exposed" and "pseudo-unexposed" groups so that differences on observed covariates resemble diff
51 tion programs need to be tightly coordinated so that different cell types are generated in the correc
52 ed to include multiple separate compartments so that differing active ingredients or formulations may
53  drugs have limited specificity and efficacy so that direct evidence for Panx1 contribution to pain h
54 t must be identified as rapidly as possible, so that directed patient treatment and/or contact precau
55 le simultaneously achieving high specificity so that diverse bitter toxins can be detected without al
56 ayer would be disrupted by laser irradiation so that drug release would be triggered remotely at the
57  and how they function in normal conditions, so that dysregulations in patients with respiratory dise
58 me environmental cue to regulate development so that each life stage is matched to its appropriate se
59          We have optimized the FISH protocol so that each round is complete in 1 min, demonstrating t
60 te stimuli that we used ultimately diverged (so that each route contained overlapping and non-overlap
61 -planar ring that interacts with the origin, so that each subunit makes unique contacts with the DNA.
62 y children who are at high risk for deficits so that early intervention can be initiated to mitigate
63 to establish a faster and accurate diagnosis so that early vitamin supplementation is considered.
64 nomas should be identified at an early stage so that effective treatment can be implemented.
65 nd closing two pinch valves interchangeably, so that either sample or solvent can enter the mixing zo
66 l potentials of both sides of the QDs layer, so that electrical current causing energy loss on the sa
67 pling between the substrate and the catalyst so that electron injection from the electrode and transp
68 duction and inverting the desalination cycle so that energy discharge coincides with salt removal (1.
69  were hidden from the challenge participants so that ENTHUSE 33 could be used for independent validat
70 es a universal positioning system for indels so that equivalent indels can be uniquely determined by
71          Optimized conjugate 16 was designed so that esterase activity will liberate 5 and cathepsin
72 e of next-generation sequencing is decreased so that even low-frequency viral variants can be accurat
73 ion, such as interpreting the visual signals so that evidence for a decision can be accumulated elsew
74 n state is inefficient in the product region so that excited-state (4) Fe(+) is the dominant product.
75 rat hippocampus displays a slow oscillation (SO) that follows "up-and-down" state transitions in the
76  adulterants make their detection difficult, so that food authentication often poses a challenge.
77 ers, the Gibbs phase rule can be generalized so that four phases can coexist even in single-component
78 hich craniofacial anomalies can be corrected so that function, esthetics, and the sense of well-being
79 a and identify the current gaps of knowledge so that future research heads toward better defining the
80 hat direct the selective expression of genes so that genetically identical cells can differentiate an
81 raction is directly sensitive to Ca(2+) ions so that high [Ca(2+)]free reduces PICK1 binding to Ago2.
82 adds an enantioselective term to the forces, so that homochiral interaction energies differ from hete
83  stepwise order of rearrangements is blocked so that IgLlambda gene rearrangements predominate in ear
84       They are complementary in fibrinolysis so that in combination, their effect is synergistic.
85 ains are contributed by two different dimers so that IN forms an open polymer mediated by inhibitor-b
86 ated a J-shaped relationship with mortality, so that in the majority of patients, there was no signif
87 pproaches to reactivate the latent reservoir so that infected cells can be recognized and targeted, w
88 sed on inducing the expression of latent HIV so that infected cells may be recognized and eliminated
89 ated (ie, uncoupled from glucose metabolism) so that insulin secretion persists in the presence of lo
90 rate a current of ions instead of electrons, so that ions can be used for potential applications in b
91 c stimulus is transferred across the saccade so that it becomes quickly available and influences proc
92 circuit supporting the trace-trained memory, so that it better reflects the circuit supporting delay
93 neralized bone that increases its compliance so that it can be embedded and easily section in paraffi
94  proposals for development of the TBARS test so that it can be used as a rapid and robust antioxidant
95 oach the performance of its individual units so that it can be used for the economical conversion of
96 sisting the release of Asp251 from ion pairs so that it can participate in proton-coupled electron tr
97 otic specific regions of the protein evolved so that it can serve as a platform for other elongation
98 s engineered to produce an epoxide hydrolase so that it efficiently removes the environmental polluta
99 populations, to shape the policy environment so that it facilitates implementation at scale with high
100    A gene drive biases inheritance of a gene so that it increases in frequency within a population ev
101  single H7 epitope by changing 3 amino acids so that it is homologous with a known H3 immunogenic epi
102 ters, such as infection and production rate, so that it is not possible to extract drug efficacy from
103 pporting the social and physical environment so that it is one in which children and their families c
104 al factors may sensitize the dopamine system so that it is vulnerable to acute stress, leading to pro
105 +) binding to Tn releases the Tpm from actin so that it moves azimuthally around the filament axis to
106 he array was randomly shuffled across trials so that it occasionally appeared in the RF, then such se
107 have been changed in its secondary structure so that it provided an enzyme like activity attributing
108 ce, where noise is added to the input signal so that it randomly exceeds the sensor threshold.
109  present only at low levels in human islets, so that it reads (GALR3) and galanin inhibited insulin s
110 hanical, metabolic, and biocultural grounds, so that it remains unclear which factors are responsible
111 o enhance epidermal nerve fiber regeneration so that it was complete within 7 days compared with 14 d
112 to a hardware system which can be engineered so that its intrinsic physics is described by the genera
113 the magnetic selection of the infected cells so that levels of background expression due to uninfecte
114 :C), suggesting that LGP2 oligomers disperse so that LGP2 can bind MDA5.
115 ion enables targeting of endosomal membranes so that light-triggered cytosolic release of an entrappe
116 odates both un-stranded and stranded RNA-seq so that lncRNAs overlapping with other genes can be pred
117 e immobilization of the bait is very stable, so that many cycles of prey injection and subsequent pre
118 er regime, experimental data are very scarce so that many theoretical models remain untested.
119 method to rank signature-projection pairings so that meaningful associations can be quickly identifie
120 tion and initiate specific voiding behaviors so that micturition occurs in environmentally and social
121                   This structure reorganizes so that minus ends are sorted to the periphery of the ar
122 generalization to the afore-mentioned method so that more adjacent SNPs can be incorporated.
123 d contraction of the variability timescales, so that most blazars appear as luminous sources characte
124 ons insert between pre-existing nucleosomes, so that multiple nearby insertions generate nucleosome-s
125 defined and controllable manner are valuable so that new modes of multiparticle dynamics can be studi
126  depend very strongly on the individual RNAs so that no general rule can be inferred.
127 strategies aim to reprogram the genetic code so that noncanonical biopolymers can be synthesized and
128 radation in CatS(-/-) B cells is incomplete, so that NTF levels are significantly lower than in SPPL2
129 importance to identify malnourished patients so that nutritional therapy can be instituted.
130 ediction rules for use in clinical practice, so that older persons' hearing help-seeking journey can
131 r initiates learning in our brain, making it so that on the very next attempt our motor commands part
132  would be sequenced by two different methods so that one assembly serves as confirmation of the other
133 te large interactions between single photons so that one photon can strongly modify the state of anot
134 tionally been treated as independent events, so that only data from an ongoing episode are considered
135 requires high levels of sequence specificity so that only molecules with very high sequence identity
136  differ in developmental potential and fate, so that only the cranial neural crest can contribute to
137  sources are relatively difficult to access, so that only the proper orchestration of many distinct c
138 rials and molecular profiling of individuals so that opportunities for targeted therapy can be exploi
139  the Ising, the XY or the Heisenberg models, so that optimization problems are reduced to finding the
140 ak NMR and MRI responses into strong signals so that ordinarily impractical measurements become possi
141 o the surface and contract to liberate space so that other polymer chains can graft onto the surface
142             We have now extended this method so that out-of-plane orientation angles can be determine
143 urface goes from hole-like to electron-like, so that p* </= p FS.
144 ng the binding properties of its miRNA guide so that pairing to the seed region is exquisitely fast a
145 and illusion, we manipulated hand ownership, so that participants embodied a rubber hand placed next
146 nt to be able to detect CVD biomarkers early so that patients can be diagnosed properly and begin tre
147 nagement is now becoming a major goal in CLL so that patients can best benefit from the increasingly
148 appropriately restrict microtubule movements so that polarity sorting by cytoplasmic dynein can occur
149              These effects offset each other so that population activity had little effect on total i
150  release decreased to approximately 58 s(-1) so that PPi release became the rate-limiting step.
151 ir functionality employ different algorithms so that predictions may vary markedly between tools.
152 ls, which remained confined within the ducts so that primary cancer did not develop.
153 unication between a NSC and its descendants, so that progeny can send feedback signals to the 'mother
154  of key questions that require our attention so that progress can be achieved in neuroscience beyond
155 weights to interaction edges in PPI networks so that protein complexes can be identified more accurat
156  the concentration of the expressed protein, so that protein purification can be avoided.
157 ight is correlated with higher isohydricity (so that rainforests are mostly isohydric).
158 ergy gap (exchange energy) is close to zero, so that rapid interconversion is possible.
159  the nature of and evidence for CAMs for IBD so that rational advice can be offered to patients who i
160 hese pairs might behave, generally speaking, so that reasonable predictions may be made regarding mol
161 Set-point adaptation balances tonic activity so that reciprocally acting, agonist and antagonist musc
162  to the metabolic dysfunction in cholecardia so that reducing serum bile acid concentrations may be b
163 he appropriate Model Organism Database (MOD) so that researchers can readily access these data alongs
164 d to effectively visualize genome structures so that researchers may better analyze genomic data.
165 degraded rapidly and in a nonlinear fashion, so that reserves are exhausted 2 h prior to dawn.
166 have shown that this matrix can be optimized so that sequence similarity scores correlate well with s
167 relates positively with the elongation rate, so that sequences using fast codons are expected to be l
168 about 1 year of allograft lifespan is traded so that sicker patients, that is, SLK transplant recipie
169  to modify the output of Robo/Slit complexes so that signaling is no longer repulsive.
170  to the diffraction peak profile broadening, so that size and strain contributions can be easily sepa
171 e suppressed by inhibitory mechanisms [3-6], so that small changes across blinks are generally not no
172 oe mass and microencapsulate lipid fraction, so that small oil droplets are entrapped within a dry ma
173 aracterizes age-related effects on the brain so that some older individuals evince clear neurocogniti
174 ect is not observed for any individual unit, so that standard approaches to cross-validation must be
175 potential to act as a source of information, so that stressed individuals could themselves act as str
176 relates with the spectral strength of water, so that strong water absorption lines are seen in clear-
177 to define parameters to standardize the AECs so that studies may be extrapolated for driving basic im
178 face oxidation under the reaction conditions so that surface Zn transforms into ZnO and allows ZnCu t
179        Motor switching events are identified so that swimming trajectories are deconstructed into a s
180 rtant for spindle integrity in mitotic cells so that tensile forces generated at kinetochores do not
181 gged sequence-matched probe DNA strand only, so that the amount of free dye removed from the probe DN
182 presumed persecutor, voiced by the therapist so that the avatar responds by becoming less hostile and
183 nsist of four short binding domains arranged so that the bricks can interlock.
184 reated congruent and incongruent situations, so that the calls of a predator were followed by playbac
185  degree of plastic strain on each shear band so that the catastrophic failure is prevented or delayed
186    These properties are spatially organized, so that the cell is most excited by clutter rather than
187 e, and marked changes in cellular morphology so that the cells resemble mesocyclic trypomastigotes.
188 amp loaders place the open clamps around DNA so that the clamps encircle DNA.
189 antibiotics (ampicillin and chloramphenicol) so that the coculture can survive in antibiotic concentr
190 es non-specific immunity to other infections so that the consequences of this transition can be effec
191  while running at an average speed of 1 m/s, so that the contact with the stimulus lasted <1 typical
192 ; however, randomisation was done in batches so that the control group and participants not yet rando
193 ing of how non-native disulfides are reduced so that the correct or native disulfides can form is poo
194  and to scale the observed expression values so that the coverage of spike-in transcripts is constant
195 te off-centering of the neighboring Nb ions, so that the Curie temperature and spontaneous polarizati
196 g the "stereoscopic correspondence problem") so that the depth of objects in the world can be triangu
197 hese assays use "pairs" of affinity reagents so that the detection signal is generated only when both
198 ha appears to twist the NFkappaB heterodimer so that the DNA can no longer bind.
199 e thicknesses of AlN barriers and GaN wells, so that the effective energy gap can be engineered from
200 iple mouse and parasite strain combinations, so that the epilepsy observed retained universality with
201 aluation of the current drug delivery field, so that the factors inhibiting rapid progress can be ide
202  simplex virus 1 (HSV-1) glycoprotein D (gD) so that the first 40 amino acids of gp120 were replaced
203 ation effect, we modify the power flow model so that the influence of time varying perturbation can b
204 a collimation of electrons across each GPNJ, so that the lack of substantial overlap between transmis
205  between the wave functions can be maximized so that the lifetime of the carrier is greatly reduced.
206 s greatly enhanced by microwave irradiation, so that the longest oxidative stability was found in MW-
207 term PPIs should be periodically reevaluated so that the lowest effective PPI dose can be prescribed
208 hrough 2003-2004, but subsequently decreased so that the mean in 2009-2010 did not differ from that i
209 ion of a structure is lost outside the cell, so that the mechanism can be understood only by observat
210 omplications should continue to be reported, so that the medical community will be better equipped to
211 model and empirical functional connectivity, so that the model's effective connectivity was a veridic
212 ipid catabolism are transcribed before birth so that the neonatal liver has a prompt capacity to extr
213 t] there exists a finite [Formula: see text] so that the observer obtains such an inference after [Fo
214 ronmentally friendly, simple, and very fast, so that the overall extraction time is only 7min.
215 ut of the cell associated with H(+) binding, so that the overall reaction is electroneutral.
216 ele that arrests female meiosis in diploids, so that the plant produces diploid egg cells that can de
217 selected by Bartlett's likelihood-ratio test so that the populations attain homogeneous variances.
218  and electronic structure theory are coupled so that the potential energy, gradient, and Hessian requ
219 r dosing followed by an "inhibition holiday" so that the potential for hypothalamic-pituitary-adrenal
220 o a sequence of convex optimization problems so that the problem can be solved by any standard optimi
221 nt cascades can be fused in a controlled way so that the products of incompatible reactions can be br
222 d in the early stage of the binding process, so that the protein is able to approach, encounter, and
223        In this Review, we address key issues so that the psychiatric clinician can better understand
224 peat domes where they are bounded by rivers, so that the rate of carbon uptake accompanying their gro
225  of the hydrocarbon and of the metal system, so that the reaction can be directed exclusively toward
226 n and deletion (indel) parameters to choose, so that the resulting sequences mimic biological data.
227 starch in broken white rice to less than 2%, so that the resulting starch can be classified to that o
228 lusion and exclusion criteria were specified so that the sample would represent healthy appropriately
229 of the protein are similar to crystal grains so that the string-like collective atomic motion is conc
230 genome dynamics and diffusion between cells, so that the synthesis of the two gives rise to the emerg
231 sible throughout the task, or by masking it, so that the task had to be performed "in the mind's eye"
232 ionability and identify potential "drivers," so that the treating physician can prioritize what clini
233 the Atlantic, SST and VWS co-vary inversely, so that the two factors act in concert to either enhance
234 n analyzing the physiology of such organisms so that the underlying physiology/pathogenesis of the or
235 g is limited by the maximum force of muscle, so that the upper chewing frequency scales as the -1/3 p
236               Ndc80 recruits the Ska complex so that the V shape of the Ska dimer interacts along pro
237 2+) ]i ) must be sufficently low in diastole so that the ventricle is relaxed and can refill with blo
238 ia the balance of gain modulation is altered so that the weaker, amblyopic eye has little effect whil
239 on of the established unweighted model above so that the weighted evolving hypergraph exhibits a scal
240 , are intrinsically chiral at a local scale, so that their activity involves torque dipoles alongside
241 s where they go through nonlinear resonance, so that their amplitude-dependent frequencies become com
242 also display such resonance Raman scattering so that their content in hydroxycinnamic acids may be qu
243  show that contact interactions are resolved so that their contribution to clock shifts is orders of
244 ES cycling by a wide range of microorganisms so that their contributions to shaping microbial communi
245 on, but in many cases areas cannot be folded so that their enlargement is constrained by anatomy, pre
246                               Plants evolved so that their flowering is triggered by seasonal changes
247 t juveniles die during the first dry season, so that their harvest just before migration has limited
248 controlling the 2D motion of active colloids so that their path has a nontrivial topology.
249 t cloud have been decoupled from each other, so that their resources are controlled independently.
250            We give methods to "program" CRNs so that their steady state is chosen from some desired t
251  elderly asthmatics in large clinical trials so that therapy may be better tailored to this at-risk a
252 natural source of antioxidant/nutraceuticals so that these antioxidants can be used for supplementing
253 e, challenging environment, driving adaption so that these can then become favorable.
254  in part by the external load on the muscle, so that these heads only attach to actin and hydrolyze A
255 uss how it can be conceptualized and managed so that these KPD innovations programs are ultimately su
256 se basal cells to neighbouring basal mitoses so that they align their horizontal division plane along
257 atively low risk of exposure to disturbances so that they are likely to provide replenishment when ot
258 e expression levels of therapeutic molecules so that they are produced locally and in direct response
259  tools are extensible, modular and flexible, so that they are tunable to particular use cases, and th
260 ere only rewarded if they chose differently, so that they benefited from hiding their actions.
261 o refine our assessment of dental phenotypes so that they better represent how the underlying genetic
262  the magnetic flux passing through the ring, so that they can be changed from diatropic ('aromatic')
263 red without being stably bound to a scaffold so that they can be efficiently recruited to release sit
264 ivate the latent reservoirs in an individual so that they can be eliminated by the immune response or
265 interoperate with existing analysis software so that they can be embedded in established work flows.
266 ware of the current status of this treatment so that they can better inform their patients who may be
267 -specific chimeric antigen receptors (CARs), so that they can combat tumour cells once they are reinf
268 ts at the selected time after administration so that they can reach their intracellular targets.
269 ces of complex syncopated drumbeats designed so that they contain no net energy at the pulse frequenc
270 ausing the torn particles to be amphiphillic so that they contribute to the formation of massive OPAs
271           One would like to choose sentinels so that they discover the outbreak as early as possible.
272 the retention of all analytes can be reduced so that they elute within their respective modulation pe
273 ofilaments and microtubules in Sertoli cells so that they failed to support cell adhesion and transpo
274 bers regulate the intrafusal fiber's stretch so that they retain proper tension and sensitivity durin
275 gn interactions between the protein subunits so that they specifically assemble into the desired stru
276 ructure in current forecast models is needed so that this growth can be corrected and forecast skill
277 of sorafenib that inhibits RVFV propagation, so that this information can be used as a tool for the f
278 the disorder from those who probably did not so that those people with a probable disorder could be r
279 th considerable turnover of membrane lipids, so that total lipid rather than TAG is the appropriate m
280  positioned as an early biomarker of disease so that treatment may be initiated earlier, resulting in
281  to two groups, stratified by serum ferritin so that two groups with similar iron statuses could be f
282 etic than the other two hexagonal materials, so that unconventional magnetically-mediated superconduc
283     Insulin secretion is precisely regulated so that, under normal physiological conditions, fasting
284 les, and therefore it erodes local diversity so that understanding the coexistence of multiple adapti
285 ggests that expected features are suppressed so that unexpected features of the speech input (Predict
286 d to an acyl carrier protein, are classified so that unusual reactions can be compared and underlying
287 , colonies derived from LAP+ cells increased so that up to 35% of the liver was repopulated by donor-
288  the jQuery and vis.js JavaScript libraries, so that users are able to interactively visualize and ed
289 ing of two cartilages (thyroid and cricoid), so that vocal fold length change is maximized.
290 eract with arousal and attentional processes so that voiding occurs under appropriate conditions.
291      The membrane acts as a low-pass filter, so that voltage and spiking mainly track the vibration e
292 lysis promotes disassembly at the other end, so that Vps4 'walks' along ESCRT-III until it encounters
293 esign and estimates of parameter uncertainty so that we can reformulate a standard cell proliferation
294  V1 neurons spanning all six cortical layers so that we could characterize the laminar position and p
295 ng inducible CDX2 embryonic stem (ES) cells, so that we could predict which CDX2-bound genes are acti
296 l the formation of fiber bundles and domains so that we explore the mechanism that causes fiber branc
297  understand the drivers of population health so that we may intervene, paving the way for healthier p
298 t angle measurement) and appropriately large so that wettability is not influenced by the presence of
299 egrated with the memory of the event itself, so that what actually occurred, and what was discussed l
300 (-1.1 mm per week of gestation; P < 0.0001), so that women who were born very preterm were on average

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