ライフサイエンスコーパス: soleus

1 nhanced insulin-stimulated glucose uptake in soleus.

2 re types with the greatest loss (55%) in the soleus.

3 iglyceride glycerol in the gastrocnemius and soleus.

4 p-regulation of fast-twitch fiber program in soleus.

5 The same was observed for ccl9 and cxcl13 in soleus.

6 much higher extent than was observed in the soleus.

7 w fibers was increased in PLN-overexpressing soleus.

8 ut did not differ significantly in the TA or soleus.

9 alpha (PGC1alpha) were investigated only in soleus.

10 inase 4 mRNA abundance in the heart, EDL and soleus.

11 ction, Y was similar to the resting value in soleus (0.34 +/- 0.14), RG (0.20 +/- 0.04) and WG (0.15

12 In resting muscle, Y was higher in soleus (0.41 +/- 0.22) versus white gastrocnemius (WG) (

13 )) were 0.034 +/- 0.001 and 0.064 +/- 0.001 (soleus), 0.031 +/- 0.001 and 0.060 +/- 0.001 (vastus), a

14 The lipid content of both the soleus (2.99 +/- 0.37 g/dL) and the MHG (3.80 +/- 0.68 g

15 s on slow fibers, precedes wasting of mutant soleus; (3) denervation is likely to drive this wasting,

16 trocnemius (24 +/- 5 versus 21 +/- 2) or the soleus (54 +/- 6 versus 70 +/- 7).

17 cific insulin-stimulated glucose uptake (71% soleus, 58% gastrocnemius) and peripheral glucose cleara

18 3 +/- 4% (mean +/-s.e.m.) of total fibres in soleus, 59 +/- 3% in vastus lateralis and 22 +/- 2% in t

19 rocnemius (39 +/- 7 versus 22 +/- 6) and the soleus (98 +/- 13 versus 65 +/- 13).

20 nscription factor, fail to accumulate in the soleus, a slow muscle, compared with fast muscles (e.g.,

21 he liver (where SIRT1 rises) or heart or the soleus, a type I muscle (where SIRT1 is unchanged).

22 ) revealed the surface-recorded amplitude of soleus action potentials was 6% of that of gastrocnemius

23 type composition (vastus lateralis, triceps, soleus) after an overnight fast and during infusion of a

24 rophy was initiated by bilateral ablation of soleus agonists 1 week before sacrifice.

25 ated an alteration in myofiber number in the soleus, an oxidative/slow-type muscle.

26 ted glucose uptake in mouse muscle by 55% in soleus and by 20-58% in extensor digitorum longus (EDL;

27 Intriguingly, the soleus and diaphragm muscles are spared of any abnormal

28 eventing the loss of function of slow-twitch soleus and diaphragm muscles.

29 Here we first show that denervation in adult soleus and EDL muscles reverses the postnatal increase i

30 Based on the similar findings in soleus and EDL muscles, fibre type does not appear to de

31 eased by 27% (P = 0.1) and 40% (P < 0.05) in soleus and EDL muscles, respectively, of muscle-specific

32 glucose uptake by 100% and 62% (P < 0.01) in soleus and EDL muscles, respectively.

33 amplitudes were significantly reduced in the soleus and extensor carpi radialis muscles at 8-11 weeks

34 action-stimulated glucose transport in mouse soleus and extensor digitorum longus (EDL) muscle.

35 ransport, and increased insulin signaling in soleus and extensor digitorum longus (EDL) muscles from

36 nsulin-stimulated glucose transport in mouse soleus and extensor digitorum longus muscles ex vivo.

37 imulated glucose uptake into the slow-twitch soleus and fast-twitch extensor digitorum longus (EDL)mu

38 In humans, during standing the calf muscles soleus and gastrocnemius actively prevent forward toppli

39 We show that soleus and gastrocnemius do indeed move paradoxically, s

40 uscle hypertrophy by surgically removing the soleus and gastrocnemius muscles in rats.

41 lipid, glucose metabolism and fiber size in soleus and gastrocnemius muscles of aged rats.

42 -stress in the feed arteries perforating the soleus and gastrocnemius muscles.

43 joint which is prevented by activity in the soleus and gastrocnemius muscles.

44 Arterioles were isolated from the soleus and gastrocnemius muscles; luminal diameter chang

45 ted to the 21 and 18% decline in V(0) in the soleus and gastrocnemius type I fibres.

46 of ultrasound images to resolve calf muscle (soleus and gastrocnemius) length changes as small as 10

47 eptive information than the active agonists (soleus and gastrocnemius).

48 tor spinae, gluteus maximus, biceps femoris, soleus and intrinsic foot (toe flexor) muscles.

49 (P < 0.05) compared to the control, whereas soleus and liver glycogen contents were less (P < 0.01 a

50 ty both increased, whereas in the shortening soleus and plantaris (PLN) muscles the increase was sign

51 The morphology of the soleus and quadriceps muscles from MGSKO mice appeared n

52 ections showed gamma2 immunostaining in both soleus and TA motoneurons and astrocytes.

53 gamma2 immunoreactivity on the soma of soleus and TA motoneurons in spinal rats was differentia

54 monitored single motor unit contractions in soleus and vastus lateralis muscles of healthy individua

55 gh significant statistically (triceps versus soleus and vastus lateralis, P < 0.05), were within appr

56 f Bcl-2, HSP70, and Mn-SOD increased in both soleus and ventricle muscles of TR animals when compared

57 in weight of the quadriceps, gastrocnemius, soleus, and even the heart itself.

58 s of interest in the tibialis anterior (TA), soleus, and medial head of the gastrocnemius (MHG) muscl

59 time to peak perfusion in the gastrocnemius, soleus, and peroneus muscles, and in the anterior compar

60 or group of hindlimb muscles (gastrocnemius, soleus, and plantaris) were evaluated in mice after comp

61 Soleus (ankle extensor) and tibialis anterior (TA, ankle

62 n quadriceps, extensor digitorum longus, and soleus approximately 10-fold, and approximately 100-fold

63 bly action potentials from gastrocnemius and soleus are represented in surface EMGs detected with dif

64 nsion in the calf muscles (gastrocnemius and soleus) are unlikely to signal postural sways on account

65 Expression of endothelial NOS (eNOS) mRNA in soleus arterioles was unaltered by ageing, whereas eNOS

66 fect how locomotion was produced: it changed soleus burst amplitude and may have induced compensatory

67 H-reflex up-conditioning increased the right soleus burst and corrected the locomotor asymmetry.

68 acking exon 15 shared this morphology in the soleus, but not other muscles.

69 Also in soleus, ccl2, interleukin (il)6, il1beta, and cluster of

70 therapy in heart, quadriceps, diaphragm, and soleus, compared with vector alone.

71 activity without substantial attenuation of soleus crosstalk.

72 Anatomical analysis indicated that 50% of soleus end plates were completely denervated 1-4 weeks p

73 licit H-reflex in leg muscles other than the soleus, especially during movement.

74 Rat soleus feed arteries were isolated, removed and mounted

75 are shown to be resistant to the decrease in soleus fiber cross-sectional area that results from 10 d

76 e cycling and MgADP release rates in skinned soleus fibers using stochastic length-perturbation analy

77 er physiological conditions in relaxed human soleus fibers, Ig domains are more stable than predicted

78 We conclude that in human soleus fibers, Ig unfolding cannot solely explain stress

79 tion and after substitution into rat skinned soleus fibers.

80 n did not increase insulin sensitivity in m. soleus from either genotype.

81 soleus from either genotype.

82 a larger increase in HSP70 expression in the soleus, gastrocnemius and lung of the WPH-fed rats than

83 At 150 min, soleus, gastrocnemius, and superficial vastus lateralis

84 Soleus H-reflex conditioning did not affect the duration

85 Over the 30 sessions, the soleus H-reflex decreased in two-thirds of the DC subjec

86 Further, the soleus H-reflex depression did not vary with the contral

87 ic and antagonistic group I afferents on the soleus H-reflex during imposed sinusoidal hip movements.

88 e swing phase of walking as observed for the soleus H-reflex elicited by tibial nerve stimulation.

89 In rats in which the soleus H-reflex elicited in the conditioning protocol (i

90 studied the impact of down-conditioning the soleus H-reflex in people with impaired locomotion cause

91 After a baseline period in which soleus H-reflex size was measured and locomotion was ass

92 The soleus H-reflex was also conditioned by medial gastrocne

93 The soleus H-reflex was conditioned by stimulating the commo

94 The soleus H-reflex was evoked every 4 s during bilateral sy

95 In each conditioning session, the soleus H-reflex was measured while the subject was or wa

96 The ipsilateral soleus H-reflex was profoundly depressed in all conditio

97 sor muscles was measured by conditioning the soleus H-reflex with stimulation of the common peroneal

98 eciprocal and pre-synaptic inhibition of the soleus H-reflex, respectively.

99 ount of inhibition acting on the ipsilateral soleus H-reflex, supporting cross-leg reflex and heteron

100 onditioned increase or decrease in the right soleus H-reflex-and examined an old behavior-locomotion.

101 alateral hip oscillations on the ipsilateral soleus H-reflex.

102 - and post-alpha motoneuronal control of the soleus H-reflex.

103 Furthermore, the PLN-overexpressing soleus had smaller muscle size, mass, and cross-sectiona

104 l selection were differentially expressed in soleus in meldonium vs. control, and a number of cellula

105 expression of class II HDAC proteins in the soleus in vivo.

106 This study compared soleus intramyocellular lipid (IMCL) concentrations afte

107 rrelated with change in the amplitude of the soleus locomotor burst, and the correlation was consiste

108 the primary findings from the work on rabbit soleus MHC-II-1.

109 ioning protocol that greatly increased right soleus motoneuron response to primary afferent input, an

110 levels of gamma2 in TA, and lower levels in soleus motoneurons.

111 Furthermore, the soleus motor responses were inhibited during the swing p

112 ll exercise failed to induce PGC-1a fully in soleus muscle (1.9- vs. 2.8-fold; P < 0.05), and in prim

113 ontent (+48%, p < 0.001) was observed in the soleus muscle (predominantly type I fibers).

114 In soleus muscle (SOL; 58 % type I fibres) total PV express

115 ssTnT-deficient soleus muscle also contains significant numbers of small

116 genesis in response to T3 was similar in the soleus muscle and heart of the young and old animals, bu

117 Fatty acid oxidation rates in the soleus muscle and in hepatocytes of Acc2-/- mice were si

118 in indirect calorimetry chambers after which soleus muscle and liver were harvested.

119 d in fibres isolated from predominantly slow soleus muscle and maintained for 4 days in culture, we n

120 s PGC-1a mRNA levels (1.5- to 5-fold) in rat soleus muscle and white gastrocnemius muscle and in mous

121 The soleus muscle and, in particular, oxidative fibres were

122 ce, increased m-calpain levels in dystrophic soleus muscle are associated with loss of Tmod1 from the

123 required for flow-induced vasodilatation in soleus muscle arterioles from young and old rats.

124 ) and l-arginine content, were determined in soleus muscle arterioles.

125 nitric oxide (NO)-mediated vasodilatation of soleus muscle arterioles.

126 sodilatation and levels of NO and O(2)(-) in soleus muscle arterioles.

127 n in endothelium-dependent vasodilatation in soleus muscle arterioles.

128 Counts of motor units to the soleus muscle as well as of axons in the soleus muscle n

129 Added foot stiffness also altered soleus muscle behaviour, leading to greater peak force (

130 ltaneous hind limb bone marrow aspiration or soleus muscle biopsy.

131 NAs regulating fuel selection was altered in soleus muscle by meldonium, highlighting the modulation

132 Na(+) and Cl(-) were quantified in the soleus muscle by using three phantoms that contained 10-

133 , with comparable expressions in slow-twitch soleus muscle containing type I and IIa fibers.

134 Surprisingly, overexpression of skMLCK in soleus muscle did not recapitulate the fast-twitch poten

135 Not surprisingly, T32KO soleus muscle expressed an elevated type I slow myosin i

136 and immunolabeling studies on relaxed human soleus muscle fibers and Monte Carlo simulations.

137 Permeabilized rat soleus muscle fibers were subjected to rapid shortening/

138 During the unloading period, soleus muscle fibre cross-section decreased by 38%.

139 rkC in the lumbar spinal cord and associated soleus muscle following 3 and 7 days of voluntary wheel

140 3.0 T of L4 for bone marrow fat content, of soleus muscle for intramyocellular lipids (IMCL), and li

141 lated glucose uptake is elevated in isolated soleus muscle from Hfe(-/-) mice (p < 0.03).

142 sitivity and reduced proinflammatory tone in soleus muscle from obese Zucker rats fed a 2DG-supplemen

143 hronic hypoxia and pulmonary inflammation on soleus muscle hypertrophic capacities, we challenged mal

144 ype 1 skeletal muscle fibers, we studied the soleus muscle in mice genetically deficient for myofiber

145 tial changes in gene expression in atrophied soleus muscle induced by hindlimb immobilization in youn

146 Using a rat strain whose soleus muscle is innervated by two nerves, we chronicall

147 tion profile of sMyBP-C in mouse slow-twitch soleus muscle isolated from fatigued or non-fatigued you

148 Slow oxidative soleus muscle maintained muscle mass, whereas fast glyco

149 the soleus muscle as well as of axons in the soleus muscle nerve showed no loss of motor neurons.

150 reased the proportion of fast-type fibers in soleus muscle of both control and LLC-bearing mice.

151 tor binding protein, was up-regulated in the soleus muscle of high sucrose diet (HSD) induced insulin

152 creased the proportion of fast-type fiber in soleus muscle of mice.

153 nd IIx mRNAs during atrophy may exist in the soleus muscle of old animals.

154 d IIx mRNAs were suppressed in the atrophied soleus muscle of old rats as opposed to the large increa

155 ne whether electrotransfer of Hsp27 into the soleus muscle of rats, prior to skeletal muscle disuse,

156 mid-mediated overexpression of Hsp70, in the soleus muscle of rats, was sufficient to regulate specif

157 ed alterations of calcium homeostasis in the soleus muscle of SHRs occurred with changes of some func

158 chain (MHC) phenotype are observed in EDL or soleus muscle of the FKBP12-deficient mice, but diaphrag

159 irst-order arterioles were isolated from the soleus muscle of young (6 months old) and old (24 months

160 hronic exercise training (6 weeks) increased soleus muscle PGC-1a mRNA levels ( approximately 25%) an

161 The soleus muscle PGC-1a response to chronic exercise was al

162 ely stimulated glucose transport in isolated soleus muscle strips of WKY rats.

163 In addition, ex vivo study of soleus muscle strips showed decreased glucose transport

164 Soleus muscle was taken for measurement of mitochondrial

165 Soleus muscle was used to determine maximal rates of ATP

166 Thus, we measured body and soleus muscle weight, food intake, and diaphragm contrac

167 ivities were derived specifically within the soleus muscle with PET images and magnetic resonance ima

168 Pretreatment of the soleus muscle with the phosphatidylinositol (PI) 3-kinas

169 t insulin sensitivity was improved in heart, soleus muscle, adipose tissue, and liver of BTBR SCD1-de

170 ease in the time to peak T2* measured in the soleus muscle, and (3) a prolongation of the posterior t

171 ional assessments of TAG levels in serum and soleus muscle, hepatic levels of adenosine triphosphate,

172 In the soleus muscle, NT-3 mRNA levels and its receptor TrkC we

173 In rats, CP-640186 lowered hepatic, soleus muscle, quadriceps muscle, and cardiac muscle mal

174 In isolated soleus muscle, recombinant CTRP1 activated AMPK signalin

175 ression by 80% and 154% in the plantaris and soleus muscle, respectively.

176 , whereas Tmod4 additionally disappears from soleus muscle, resulting in thin filament length increas

177 However, in the treated mdx soleus muscle, the percentage of slow fibers was signifi

178 In soleus muscle, we reported a greater capacity to cultiva

179 y observable in the non-weight-bearing (NWB) soleus muscle, which undergoes a slow-to-fast fiber type

180 and white gastrocnemius muscle and in mouse soleus muscle, which was prevented by pretreatment with

181 aracterized the resulting changes in in vivo soleus muscle-tendon mechanics using ultrasonography.

182 in mitochondria isolated from the liver and soleus muscle.

183 and Akt (Ser(473) and Thr(308)) in liver and soleus muscle.

184 or (BDNF) in both the lumbar spinal cord and soleus muscle.

185 force production in the mutant diaphragm or soleus muscle.

186 muscle yet had no effect on the slow-twitch soleus muscle.

187 ary densities (angiogenesis) in the ischemic soleus muscle.

188 ficantly reduced the tolerance to fatigue in soleus muscle.

189 d concentrations of TAG in liver, serum, and soleus muscle.

190 used male rats and induced an injury of the soleus muscle.

191 nd mitochondrial biogenesis in the oxidative soleus muscle.

192 contractile force (30%) in adult slow twitch soleus muscles (SOL) with no effect on fast twitch exten

193 esulted in significant protection of EDL and soleus muscles against a normally damaging contraction p

194 ated glucose uptake in tibialis anterior and soleus muscles and brown adipose tissue, suggesting that

195 an index of vasoconstriction in slow-twitch soleus muscles and fast-twitch extensor digitorum longus

196 ections did not affect macrophage numbers in soleus muscles at 2 days of reloading, macrophages were

197 tion in fast-twitch muscle were activated in soleus muscles by treatment with the nitric oxide (NO) d

198 Overexpression of dominant negative Nedd4 in soleus muscles completely reversed the unloading-induced

199 t confirmed increased mRNA expression in rat soleus muscles due to 1-14 days of hind limb unloading.

200 In both mdx and mdx/mTR mice, both TA and soleus muscles exhibit normal localization of alpha-acti

201 f intact extensor digitorum longus (EDL) and soleus muscles from Mtm1delta4 mice, which produce no my

202 les from WT mice was completely abolished in soleus muscles from Nfkb1 knockout mice.

203 activation of the NF-kappaB reporter gene in soleus muscles from WT mice was completely abolished in

204 vation was explored by partially denervating soleus muscles in mice lacking presynaptic NCAM (Hb9(cre

205 HGF significantly enhanced DOGU in mouse soleus muscles in vitro.

206 Fibers (n = 16) were obtained from the soleus muscles of adult male rats and the middle portion

207 Bundles of intact fibres from soleus muscles of adult mice were isolated by dissection

208 Soleus muscles of constitutive Orai-KO mice exhibited a

209 Extensor digitorum longus and soleus muscles of MSTN(Delta/Delta) rats demonstrated 20

210 The soleus muscles of Myo-Cre/Flox-MCIP1 mice fatigued more

211 ies were obtained from the gastrocnemius and soleus muscles of nine International Space Station crew

212 Soleus muscles of non-transgenic mice showed significant

213 nd IIx mRNA with micoarrays in the atrophied soleus muscles of old rats, but they were found to incre

214 In addition, soleus muscles of SHR showed reduced activity of the sar

215 lar calcium of extensor digitorum longus and soleus muscles of SHRs were differently altered with res

216 In diaphragm and soleus muscles of the knockdown and knockout mouse model

217 expression was elevated in the plantaris and soleus muscles of the trained animals compared to the se

218 mRNA levels increased in both ventricle and soleus muscles of TR animals, and Bax mRNA levels decrea

219 Overexpression of wild-type Nedd4 in soleus muscles of weight bearing rats caused a decrease

220 We observed that MPO-/-soleus muscles showed a significant 52% reduction in mem

221 a dominant negative (d.n.) IKKbeta into rat soleus muscles showed complete inhibition of 7-day disus

222 ormed global gene expression analysis of rat soleus muscles using Affymetrix GeneChips at 1, 4, 7 and

223 d extensor digitorum longus muscle (EDL) and soleus muscles were collected.

224 Rat soleus muscles were electroporated with green fluorescen

225 Subsequently, the gastrocnemius complex and soleus muscles were excised and all feed arteries were c

226 trocnemius, superficial vastus lateralis and soleus muscles were excised at 120 min to determine 2-(3

227 When atrophied soleus muscles were injected intramuscularly with M-CSF,

228 or 12 h, extensor digitorum longus (EDL) and soleus muscles were removed and subjected to a (normally

229 re and capillary density in the fetal TB and soleus muscles, and mRNA levels in the TB of insulin rec

230 months, vastus lateralis, rectus femoris and soleus muscles, from AL-fed rats, had significant muscle

231 le function in extensor digitorum longus and soleus muscles, including peak stress and time to fatigu

232 In soleus muscles, incubation with phenylephrine (PE) or UK

233 Js in partially denervated Hb9(cre)NCAM(flx) soleus muscles, one with high (mature) quantal content,

234 Like the soleus muscles, plantaris muscles from Nfkb1(-/-) and Bc

235 sites in old wild type and young or old mdx soleus muscles, respectively.

236 ic sites in young fatigued wild type and mdx soleus muscles, respectively.

237 oximately 10 and approximately 12% in TA and soleus muscles, respectively.

238 nted ends in both tibialis anterior (TA) and soleus muscles, whereas Tmod4 additionally disappears fr

239 d a decrease in fiber size of weight-bearing soleus muscles, while muscles overexpressing w.t. IKKbet

240 lin (450 microU/ml) was measured in isolated soleus muscles.

241 terior and extensor digitorum longus but not soleus muscles.

242 rts tetanic force development in slow twitch soleus muscles.

243 ays of reloading, compared with PBS-injected soleus muscles.

244 of flexor (tibialis anterior) and extensor (soleus) muscles associated with a fixed-trajectory and a

245 tus lateralis and rectus femoris but not the soleus of AL-fed rats.

246 d mitochondrial biogenesis were increased in soleus of apelin-treated mice.

247 ivo T2 relaxation data was acquired from the soleus of eight healthy volunteers using a localized Car

248 The soleus of the immobilized-reambulated hindlimb was found

249 he TR group decreased by 15% whereas that in soleus of the TR group tended to decrease (P=0.058) when

250 Apaf-1 protein content in the soleus of TR animals was lower than that of CON animals.

251 nimals, and Bax mRNA levels decreased in the soleus of TR animals when compared with CON animals.

252 densities were lower in the TB, but not the soleus, of PI and L fetuses.

253 diaphragm of the mutant mice but not in the soleus or EDL.

254 243 patients (63.2%) and a muscular branch (soleus or gastrocnemius) in 215 (56.0%).

255 ot in quadriceps, extensor digitorum longus, soleus, or ventricle.

256 ent was lower in skeletal muscles, including soleus (P<0.01), extensor digitorum longus (EDL; P<0.001

257 , starvation, and diabetes led to atrophy of soleus, plantaris, and gastrocnemius muscles, but only u

258 On the seventh day, the gastrocnemius-soleus-plantaris muscle group was isolated and snap froz

259 and DNA fragmentation) were investigated in soleus (predominately Type I fiber), and superficial vas

260 e ankle extensors, medial gastrocnemius, and soleus, remained intact, with little pre- or postsynapti

261 res were prepared from the gastrocnemius and soleus, respectively, mounted between a force transducer

262 Gastrocnemius and soleus Rg were greater in exercising compared with seden

263 ce and their wild-type (WT) littermates: the soleus (S and FR MU); and the extensor digitorum longus

264 the number of mitochondria in white and red (soleus) skeletal muscle.

265 ii (TB, slow- and fast-twitch myofibres) and soleus (slow-twitch myofibres) muscles.

266 f any, muscle fascicles of denervated feline soleus (SO) change length during stance of walking when

267 Isolated soleus (SOL) and gastrocnemius (GAS) muscle arterioles w

268 nd electromyographic (EMG) activity from the soleus (SOL) and medial gastrocnemius (MG).

269 y, we assessed the effect of up-conditioning soleus (SOL) H-reflex on SOL and tibialis anterior (TA)

270 cacy at the synapse between Ia afferents and soleus (Sol) motoneurones.

271 recorded from the tibialis anterior (TA) and soleus (Sol) muscles during treadmill locomotion and kin

272 isolated extensor digitorum longus (EDL) and soleus (SOL) muscles.

273 elevated in gastrocnemius (GA), but not the soleus (SOL) or plantaris (PLT) muscles, of D14 mice.

274 extensor digitorum longus muscle (EDL) than soleus (SOL), but we find these rates are not distinguis

275 52 m/s), we measured the EMG activity of the soleus (SOL), medial gastrocnemius (MG), tibialis anteri

276 high intensities (Hi, 4.5 V) in rat (n = 20) soleus (Sol, slow-twitch, type I), mixed gastrocnemius (

277 scle comprising predominately type I fibres (soleus, Sol, 86 % type I) would, based on demonstrated b

278 Electromyographic responses recorded in soleus (standing patients) and the erectores spinae (all

279 the left E-box actually raised expression in soleus, suggesting a possible repressor role for this co

280 and apparent AS160 PAS phosphorylation among soleus, tibialis anterior, and extensor digitorum longus

281 ralis, rectus femoris, medial gastrocnemius, soleus, tibialis anterior, extensor digitorum brevis and

282 w during early postnatal development and, in soleus, to a reduction in number of fibers generated.

283 inhibitory effects of PLN on the transgenic soleus twitch kinetics.

284 ower with the hierarchy of the effects being soleus type I > soleus type II > gastrocnemius type I >

285 the loss of peak force (P(0)), which for the soleus type I fibre declined 35% from 0.86 to 0.56 mN.

286 was fibre atrophy, which averaged 20% in the soleus type I fibres (98 to 79 mum diameter).

287 erarchy of the effects being soleus type I > soleus type II > gastrocnemius type I > gastrocnemius ty

288 ponent Hill-type model of the human Achilles-soleus unit.

289 .04) and WG (0.15 +/- 0.08); Y was higher in soleus versus both RG and WG during contraction.

290 muscle (WG) during rest and in slow-twitch (soleus) versus fast-twitch (RG and WG) muscle during con

291 gher relative anaplerotic flux in oxidative (soleus) versus glycolytic muscle (WG) during rest and in

292 Young adult mutant soleus was drastically wasted, with highly atrophied typ

293 Myopathic alterations in soleus were apparent by 12 mo, including abnormally dist

294 vels and the PLN/SERCA2a ratio in transgenic soleus were comparable with those in cardiac muscle.

295 Gastrocnemius and soleus were usually (duration 71 +/- 23 and 81 +/- 16%,

296 nic mice with PLN-specific overexpression in soleus, which is largely composed of slow-muscle fibers.

297 uscular EMGs detected from gastrocnemius and soleus while five participants stood upright.

298 [Ca(2+)](rest), and present muscle damage in soleus with a strong sex bias.

299 rest was similar between young and old rats (soleus: Y, 65 +/- 5; O, 64 +/- 5 dynes cm(-2); gastrocne

300 additional feed artery perforating both the soleus (young, 3.3 +/- 0.2; old, 2.6 +/- 0.2 vessels; P