ライフサイエンスコーパス: soleus muscle

1 and Akt (Ser(473) and Thr(308)) in liver and soleus muscle.

2 or (BDNF) in both the lumbar spinal cord and soleus muscle.

3 force production in the mutant diaphragm or soleus muscle.

4 or SB203580 in the predominantly slow-twitch soleus muscle.

5 bed, to assess the IMCL content of isolated soleus muscle.

6 ally insulin-stimulated 3MG transport in the soleus muscle.

7 adenine translocator is lost in desmin-null soleus muscle.

8 cle or in small bundles from the slow-twitch soleus muscle.

9 s and was longer than average for units from soleus muscle.

10 ary densities (angiogenesis) in the ischemic soleus muscle.

11 ficantly reduced the tolerance to fatigue in soleus muscle.

12 d concentrations of TAG in liver, serum, and soleus muscle.

13 used male rats and induced an injury of the soleus muscle.

14 nd mitochondrial biogenesis in the oxidative soleus muscle.

15 in mitochondria isolated from the liver and soleus muscle.

16 muscle yet had no effect on the slow-twitch soleus muscle.

17 and soleus muscles and for absolute power of soleus muscles.

18 rts tetanic force development in slow twitch soleus muscles.

19 them in in situ hybridization studies of rat soleus muscles.

20 3 when overexpressed in electroporated adult soleus muscles.

21 transport in isolated rat epitrochlearis and soleus muscles.

22 ions and decreased cytosolic fractions of GK soleus muscles.

23 ls were not changed in either fraction in GK soleus muscles.

24 en studied in the isolated white EDL and red soleus muscles.

25 m content of fibres from rabbit masseter and soleus muscles.

26 ays of reloading, compared with PBS-injected soleus muscles.

27 lin (450 microU/ml) was measured in isolated soleus muscles.

28 terior and extensor digitorum longus but not soleus muscles.

29 1 +/- 0.34 vs. 0.68 +/- 0.11, P = 0.002) and soleus muscles (0.31 +/- 0.07 vs. 0.09 +/- 0.02, P = 0.0

30 ll exercise failed to induce PGC-1a fully in soleus muscle (1.9- vs. 2.8-fold; P < 0.05), and in prim

31 fy IMCL and EMCL triglyceride content of the soleus muscle, 2) a 2-h euglycemic-hyperinsulinemic clam

32 and caused a reduction in expression in the soleus muscle (a muscle with many slow fibers) but did n

33 t insulin sensitivity was improved in heart, soleus muscle, adipose tissue, and liver of BTBR SCD1-de

34 esulted in significant protection of EDL and soleus muscles against a normally damaging contraction p

35 ssTnT-deficient soleus muscle also contains significant numbers of small

36 bserved in insulin-induced glucose uptake in soleus muscle and epididymal fat; insulin inhibition of

37 genesis in response to T3 was similar in the soleus muscle and heart of the young and old animals, bu

38 Fatty acid oxidation rates in the soleus muscle and in hepatocytes of Acc2-/- mice were si

39 in indirect calorimetry chambers after which soleus muscle and liver were harvested.

40 d in fibres isolated from predominantly slow soleus muscle and maintained for 4 days in culture, we n

41 ignificant reduction of type I fibers in the soleus muscle and type IIa fibers in the plantaris muscl

42 s PGC-1a mRNA levels (1.5- to 5-fold) in rat soleus muscle and white gastrocnemius muscle and in mous

43 The soleus muscle and, in particular, oxidative fibres were

44 ated glucose uptake in tibialis anterior and soleus muscles and brown adipose tissue, suggesting that

45 an index of vasoconstriction in slow-twitch soleus muscles and fast-twitch extensor digitorum longus

46 l values for absolute force for both EDL and soleus muscles and for absolute power of soleus muscles.

47 ease in the time to peak T2* measured in the soleus muscle, and (3) a prolongation of the posterior t

48 stent translocation and activation of PKC in soleus muscles, and (2) this persistent PKC activation m

49 re and capillary density in the fetal TB and soleus muscles, and mRNA levels in the TB of insulin rec

50 ce, increased m-calpain levels in dystrophic soleus muscle are associated with loss of Tmod1 from the

51 required for flow-induced vasodilatation in soleus muscle arterioles from young and old rats.

52 n in endothelium-dependent vasodilatation in soleus muscle arterioles.

53 ) and l-arginine content, were determined in soleus muscle arterioles.

54 nitric oxide (NO)-mediated vasodilatation of soleus muscle arterioles.

55 sodilatation and levels of NO and O(2)(-) in soleus muscle arterioles.

56 Counts of motor units to the soleus muscle as well as of axons in the soleus muscle n

57 of flexor (tibialis anterior) and extensor (soleus) muscles associated with a fixed-trajectory and a

58 ections did not affect macrophage numbers in soleus muscles at 2 days of reloading, macrophages were

59 ormation, were examined in rat gastrocnemius-soleus muscles at rest and during contractions induced b

60 Added foot stiffness also altered soleus muscle behaviour, leading to greater peak force (

61 ltaneous hind limb bone marrow aspiration or soleus muscle biopsy.

62 In the absence of flow restriction, soleus muscle blood flow increased from 18.9 +/- 3.8 to

63 In the stenosis group, soleus muscle blood flow increased from 9.8 +/- 2.3 to 2

64 In the stenosis group, soleus muscle blood flow increased from 9.8 +/- 2.3 to 2

65 on of an NF-kappaB-dependent reporter in rat soleus muscle but not the atrophy-resistant extensor dig

66 rmal resting 2-deoxy-glucose (2DG) uptake in soleus muscles but had no significant response to insuli

67 ncrease in rigor tension in both gizzard and soleus muscles, but a decrease in psoas muscle.

68 NAs regulating fuel selection was altered in soleus muscle by meldonium, highlighting the modulation

69 Na(+) and Cl(-) were quantified in the soleus muscle by using three phantoms that contained 10-

70 ncreased glucose uptake in gastrocnemius and soleus muscles by 44 and 47%, respectively.

71 tion in fast-twitch muscle were activated in soleus muscles by treatment with the nitric oxide (NO) d

72 ificantly reduced in desmin-null cardiac and soleus muscle compared with controls.

73 Overexpression of dominant negative Nedd4 in soleus muscles completely reversed the unloading-induced

74 , with comparable expressions in slow-twitch soleus muscle containing type I and IIa fibers.

75 Inhibition declined during soleus muscle contraction in sitting, standing and bicyc

76 Surprisingly, overexpression of skMLCK in soleus muscle did not recapitulate the fast-twitch poten

77 t confirmed increased mRNA expression in rat soleus muscles due to 1-14 days of hind limb unloading.

78 In both mdx and mdx/mTR mice, both TA and soleus muscles exhibit normal localization of alpha-acti

79 Not surprisingly, T32KO soleus muscle expressed an elevated type I slow myosin i

80 In contrast, insulin decreased soleus muscle FA oxidation by 40% (P < 0.001) and increa

81 Leptin increased soleus muscle FA oxidation by 42% (P < 0.001) and decrea

82 and immunolabeling studies on relaxed human soleus muscle fibers and Monte Carlo simulations.

83 Permeabilized rat soleus muscle fibers were subjected to rapid shortening/

84 Permeabilized rat soleus muscle fibers were subjected to repeated triangul

85 e made from dually innervated neonatal mouse soleus muscle fibers, and quantal content and paired-pul

86 For comparison, we also tested psoas and soleus muscle fibers.

87 nloaded shortening velocity of human skinned soleus muscle fibers.

88 During the unloading period, soleus muscle fibre cross-section decreased by 38%.

89 maximum shortening velocity (V0) observed in soleus muscle fibres expressing the beta/slow MyHC isofo

90 Isolated soleus muscle fibres from aged rats contract more slowly

91 rkC in the lumbar spinal cord and associated soleus muscle following 3 and 7 days of voluntary wheel

92 3.0 T of L4 for bone marrow fat content, of soleus muscle for intramyocellular lipids (IMCL), and li

93 lated glucose uptake is elevated in isolated soleus muscle from Hfe(-/-) mice (p < 0.03).

94 ase I, II, and total activity were normal in soleus muscle from high-fat-fed mice.

95 were decreased by 30-60% but were normal for soleus muscle from male IRAP-/- mice.

96 sitivity and reduced proinflammatory tone in soleus muscle from obese Zucker rats fed a 2DG-supplemen

97 GLUT4 expression in soleus muscle from the high-fat-fed mice was also normal

98 Soleus muscles from male Glut 4-null mice took up twice

99 f intact extensor digitorum longus (EDL) and soleus muscles from Mtm1delta4 mice, which produce no my

100 les from WT mice was completely abolished in soleus muscles from Nfkb1 knockout mice.

101 Heart and soleus muscles from these animals are depigmented, but f

102 Soleus muscles from transgenic animals exhibited a great

103 activation of the NF-kappaB reporter gene in soleus muscles from WT mice was completely abolished in

104 months, vastus lateralis, rectus femoris and soleus muscles, from AL-fed rats, had significant muscle

105 in stimulated whole-body glucose disposal or soleus muscle glucose transport activity.

106 ional assessments of TAG levels in serum and soleus muscle, hepatic levels of adenosine triphosphate,

107 hronic hypoxia and pulmonary inflammation on soleus muscle hypertrophic capacities, we challenged mal

108 Presynaptic inhibition of soleus muscle Ia afferent fibres, produced by stimulatio

109 ype 1 skeletal muscle fibers, we studied the soleus muscle in mice genetically deficient for myofiber

110 patients (1.4%), and partial rupture of the soleus muscle in one patient (0.7%).

111 vation was explored by partially denervating soleus muscles in mice lacking presynaptic NCAM (Hb9(cre

112 Incubation of isolated soleus muscles in vitro with epinephrine (10(-5) mol/l)

113 HGF significantly enhanced DOGU in mouse soleus muscles in vitro.

114 le function in extensor digitorum longus and soleus muscles, including peak stress and time to fatigu

115 nges in malonyl CoA and ACC were observed in soleus muscle incubated with gACRP30 (2.5 micro g/ml), a

116 lucose (2DG) uptake was measured in isolated soleus muscles incubated in vitro in the presence or abs

117 sed insulin effects on glycogen synthesis in soleus muscles incubated in vitro.

118 In soleus muscles, incubation with phenylephrine (PE) or UK

119 tial changes in gene expression in atrophied soleus muscle induced by hindlimb immobilization in youn

120 Using a rat strain whose soleus muscle is innervated by two nerves, we chronicall

121 tion profile of sMyBP-C in mouse slow-twitch soleus muscle isolated from fatigued or non-fatigued you

122 Slow oxidative soleus muscle maintained muscle mass, whereas fast glyco

123 In the soleus muscle, mRNA for both beta-myosin heavy chains an

124 using in vivo somatic gene transfer into rat soleus muscles (n = 804) to identify region(s) that are

125 the soleus muscle as well as of axons in the soleus muscle nerve showed no loss of motor neurons.

126 In the soleus muscle, NT-3 mRNA levels and its receptor TrkC we

127 ral patterning of motor unit activity in the soleus muscle of awake, behaving neonatal mice, and that

128 reased the proportion of fast-type fibers in soleus muscle of both control and LLC-bearing mice.

129 e white adipose tissue (WAT) and slow-twitch soleus muscle of both sexes of MLC-GLUT4-null mice.

130 tor binding protein, was up-regulated in the soleus muscle of high sucrose diet (HSD) induced insulin

131 creased the proportion of fast-type fiber in soleus muscle of mice.

132 In contrast, 2-DOG uptake in slow-twitch soleus muscle of MLC-GLUT4-null mice was not normalized.

133 nd IIx mRNAs during atrophy may exist in the soleus muscle of old animals.

134 d IIx mRNAs were suppressed in the atrophied soleus muscle of old rats as opposed to the large increa

135 ne whether electrotransfer of Hsp27 into the soleus muscle of rats, prior to skeletal muscle disuse,

136 mid-mediated overexpression of Hsp70, in the soleus muscle of rats, was sufficient to regulate specif

137 As that were expressed differentially in the soleus muscle of sham-operated vs. gastrocnemius-ablated

138 ed alterations of calcium homeostasis in the soleus muscle of SHRs occurred with changes of some func

139 The fatty acid oxidation rate in the soleus muscle of the Acc2-/- mice was 30% higher than th

140 chain (MHC) phenotype are observed in EDL or soleus muscle of the FKBP12-deficient mice, but diaphrag

141 irst-order arterioles were isolated from the soleus muscle of young (6 months old) and old (24 months

142 Fibers (n = 16) were obtained from the soleus muscles of adult male rats and the middle portion

143 Bundles of intact fibres from soleus muscles of adult mice were isolated by dissection

144 were increased, and PKC was translocated, in soleus muscles of both (1) normoglycemic hyperinsulinemi

145 Soleus muscles of constitutive Orai-KO mice exhibited a

146 ation, membrane PKC levels were decreased in soleus muscles of hyperglycemic streptozotocin (STZ)-ind

147 glycogen synthesis and insulin resistance in soleus muscles of hyperinsulinemic type II diabetic Goto

148 ange in the decline in the masses of EDL and soleus muscles of mdx and control mice was from 16 to 28

149 nd, even at 28 months, the masses of EDL and soleus muscles of mdx mice were 17 % and 22 % greater th

150 Extensor digitorum longus and soleus muscles of MSTN(Delta/Delta) rats demonstrated 20

151 The soleus muscles of Myo-Cre/Flox-MCIP1 mice fatigued more

152 ies were obtained from the gastrocnemius and soleus muscles of nine International Space Station crew

153 Soleus muscles of non-transgenic mice showed significant

154 nd IIx mRNA with micoarrays in the atrophied soleus muscles of old rats, but they were found to incre

155 e fibre segments (n = 16) were obtained from soleus muscles of rats.

156 In addition, soleus muscles of SHR showed reduced activity of the sar

157 lar calcium of extensor digitorum longus and soleus muscles of SHRs were differently altered with res

158 mary afferents from medial gastrocnemius and soleus muscles of the cat to study the modulating effect

159 In diaphragm and soleus muscles of the knockdown and knockout mouse model

160 expression was elevated in the plantaris and soleus muscles of the trained animals compared to the se

161 mRNA levels increased in both ventricle and soleus muscles of TR animals, and Bax mRNA levels decrea

162 Overexpression of wild-type Nedd4 in soleus muscles of weight bearing rats caused a decrease

163 Js in partially denervated Hb9(cre)NCAM(flx) soleus muscles, one with high (mature) quantal content,

164 s with high oxidative capacities such as red soleus muscle or liver, while transcript levels were red

165 hronic exercise training (6 weeks) increased soleus muscle PGC-1a mRNA levels ( approximately 25%) an

166 The soleus muscle PGC-1a response to chronic exercise was al

167 Like the soleus muscles, plantaris muscles from Nfkb1(-/-) and Bc

168 ontent (+48%, p < 0.001) was observed in the soleus muscle (predominantly type I fibers).

169 ar brown adipose tissue and in gastrocnemius/soleus muscle preparations from the obesity-resistant A/

170 In rats, CP-640186 lowered hepatic, soleus muscle, quadriceps muscle, and cardiac muscle mal

171 In isolated soleus muscle, recombinant CTRP1 activated AMPK signalin

172 was decreased 35-45% (P < 0.001) in isolated soleus muscle, regardless of diet duration.

173 We found that, in rat epitrochlearis and soleus muscles, removing adenosine with adenosine deamin

174 yceride/h for quadriceps, gastrocnemius, and soleus muscle, respectively).

175 ression by 80% and 154% in the plantaris and soleus muscle, respectively.

176 sites in old wild type and young or old mdx soleus muscles, respectively.

177 ic sites in young fatigued wild type and mdx soleus muscles, respectively.

178 oximately 10 and approximately 12% in TA and soleus muscles, respectively.

179 , whereas Tmod4 additionally disappears from soleus muscle, resulting in thin filament length increas

180 We observed that MPO-/-soleus muscles showed a significant 52% reduction in mem

181 a dominant negative (d.n.) IKKbeta into rat soleus muscles showed complete inhibition of 7-day disus

182 on the solid surface, the gastrocnemius and soleus muscles showed peak responses at latencies of 53

183 In soleus muscle (SOL; 58 % type I fibres) total PV express

184 contractile force (30%) in adult slow twitch soleus muscles (SOL) with no effect on fast twitch exten

185 mulated transport of [3H]2-deoxyglucose into soleus muscle strips confirmed the insulin resistance fo

186 ely stimulated glucose transport in isolated soleus muscle strips of WKY rats.

187 In addition, ex vivo study of soleus muscle strips showed decreased glucose transport

188 aracterized the resulting changes in in vivo soleus muscle-tendon mechanics using ultrasonography.

189 However, in the treated mdx soleus muscle, the percentage of slow fibers was signifi

190 We found that exposure of soleus muscles to 6 nmol/l TNF-alpha for 45 min in vitro

191 ormed global gene expression analysis of rat soleus muscles using Affymetrix GeneChips at 1, 4, 7 and

192 0 for slow-twitch fibres from rabbit and rat soleus muscle was 0.08 +/- 0.02 and 0.10 +/- 0.04 pCa un

193 mulated 3-O-methylglucose uptake in isolated soleus muscle was 54% greater in C/EBPbeta(-/-) mice (p

194 The soleus muscle was cast-immobilized in a shortened positi

195 n between calmodulin and IRS proteins in rat soleus muscle was enhanced when insulin resistance was i

196 lin-stimulated glucose oxidation in isolated soleus muscle was significantly augmented in pioglitazon

197 Soleus muscle was taken for measurement of mitochondrial

198 ion of HOE 140, functional hyperaemia in the soleus muscle was unaffected (blood flow, 17.8 +/- 2.2 m

199 ion of HOE 140, functional hyperaemia in the soleus muscle was unaffected (blood flow, 17.8 +/- 2.2 m

200 Soleus muscle was used to determine maximal rates of ATP

201 into rat extensor digitorum longus (EDL) and soleus muscles was facilitated by the sodium ionophore m

202 In soleus muscle, we reported a greater capacity to cultiva

203 ulinemia contributed to PKC activation in GK soleus muscles, we found that DAG levels were increased,

204 nrichment in extracts of individual hindlimb soleus muscles weighing approximately 150 mg and contain

205 Thus, we measured body and soleus muscle weight, food intake, and diaphragm contrac

206 Both the IMCL and EMCL content of the soleus muscle were significantly greater in the obese ad

207 that while EDL muscles behaved as expected, soleus muscles were able to take up a large amount of gl

208 d extensor digitorum longus muscle (EDL) and soleus muscles were collected.

209 Rat soleus muscles were electroporated with green fluorescen

210 Subsequently, the gastrocnemius complex and soleus muscles were excised and all feed arteries were c

211 trocnemius, superficial vastus lateralis and soleus muscles were excised at 120 min to determine 2-(3

212 When atrophied soleus muscles were injected intramuscularly with M-CSF,

213 or 12 h, extensor digitorum longus (EDL) and soleus muscles were removed and subjected to a (normally

214 nted ends in both tibialis anterior (TA) and soleus muscles, whereas Tmod4 additionally disappears fr

215 Introduction of EDTA into rat soleus muscle, which has low [PA], increased the relaxat

216 y observable in the non-weight-bearing (NWB) soleus muscle, which undergoes a slow-to-fast fiber type

217 and white gastrocnemius muscle and in mouse soleus muscle, which was prevented by pretreatment with

218 d a decrease in fiber size of weight-bearing soleus muscles, while muscles overexpressing w.t. IKKbet

219 ivities were derived specifically within the soleus muscle with PET images and magnetic resonance ima

220 Pretreatment of the soleus muscle with the phosphatidylinositol (PI) 3-kinas

221 Incubation of epitrochlearis and soleus muscles with 6 nmol/l TNF-alpha for 45 min or 4 h

222 aponeuroses of the medial gastrocnemius and soleus muscles without muscle rupture in 30 patients (21