ライフサイエンスコーパス: solid-phase peptide synthesis

1 synthesis and chemically incorporated using solid phase peptide synthesis.

2 JB3 was generated by solid phase peptide synthesis.

3 carboxylic acid as a building block for Fmoc solid phase peptide synthesis.

4 mmunoaffinity chromatography and prepared by solid phase peptide synthesis.

5 the preparation of derivatives suitable for solid phase peptide synthesis.

6 onto the N-terminus of a peptide segment by solid phase peptide synthesis.

7 ogenes as effectively as melittin created by solid phase peptide synthesis.

8 nd analogs were generated through Fmoc-based solid phase peptide synthesis.

9 ur peptide fragments, themselves prepared by solid phase peptide synthesis.

10 internalization and are compatible with Fmoc solid phase peptide synthesis.

11 orporated into the peptides by standard Fmoc solid phase peptide synthesis.

12 ral Fmoc-d-Hot horizontal lineTap-ketals for solid-phase peptide synthesis.

13 acetate (TFA) is a strong anion byproduct of solid-phase peptide synthesis.

14 ave been synthesized in a modular fashion by solid-phase peptide synthesis.

15 2 by 9-fluorenylmethoxycarbonyl (Fmoc)-based solid-phase peptide synthesis.

16 which can be readily used in subsequent Fmoc solid-phase peptide synthesis.

17 ptide on a solid support in conjunction with solid-phase peptide synthesis.

18 gue bearing N(alpha)-protection suitable for solid-phase peptide synthesis.

19 d particles and applied to reactions used in solid-phase peptide synthesis.

20 ide by fluorenylmethoxycarbonyl (Fmoc)-based solid-phase peptide synthesis.

21 used to cleave and deprotect peptides after solid-phase peptide synthesis.

22 trained substance P analogue with the use of solid-phase peptide synthesis.

23 from influenza B was synthesized by standard solid-phase peptide synthesis.

24 -Arg-Thr-Pen]-Thr-NH(2), 1) were prepared by solid-phase peptide synthesis.

25 ral imaging spectrometer was used to monitor solid-phase peptide synthesis.

26 le, supports is an attractive alternative to solid-phase peptide synthesis.

27 ragments and have used them as units in Fmoc solid-phase peptide synthesis.

28 obtained compounds are suitable for standard solid-phase peptide synthesis.

29 ype primary sequence, themselves obtained by solid-phase peptide synthesis.

30 AM analogs were synthesized through solid-phase peptide synthesis.

31 blocks, fully compatible with standard Fmoc solid-phase peptide synthesis.

32 purified uPLB and pPLB standards produced by solid-phase peptide synthesis.

33 igopeptides site-specifically using standard solid-phase peptide synthesis.

34 amide bond is compatible with Fmoc-chemistry solid-phase peptide synthesis.

35 yl chloride resin by conventional Fmoc-based solid-phase peptide synthesis.

36 a suitably protected analogue for Fmoc-based solid-phase peptide synthesis.

37 rategy that is compatible with standard Fmoc solid-phase peptide synthesis.

38 H (1c) as ordinary amino acids in Fmoc-based solid-phase peptide synthesis.

39 y be incorporated into peptides via standard solid-phase peptide synthesis.

40 as incorporated into VM(11)VVQTK by standard solid-phase peptide synthesis.

41 hesized appropriately protected for Fmoc/Boc solid-phase peptide synthesis.

42 been recognized as a challenging target for solid-phase peptide synthesis.

43 , we find that this fragment, synthesized by solid-phase peptide synthesis, also forms fibrillar stru

44 We have thus demonstrated that using solid phase peptide synthesis and chemical ligation it i

45 ully carboxylated Gla domain of Factor IX by solid phase peptide synthesis and crystallized Factor IX

46 re synthesized by a tandem combination using solid phase peptide synthesis and microwave-assisted rea

47 The protein is synthesized using Fmoc-based solid-phase peptide synthesis and assembled using combin

48 he protein, a 22-mer peptide, is prepared by solid-phase peptide synthesis and contains the F(n)Y at

49 and PLA2-(59-124) were prepared by stepwise solid-phase peptide synthesis and ligated to yield a pep

50 pHis analogues were successfully utilized in solid-phase peptide synthesis and semi-synthesis of hist

51 ic fragment LLELI[13C615N1]R was prepared by solid-phase peptide synthesis and was used as an interna

52 ated into peptides using Boc-chemistry-based solid-phase peptide synthesis, and in three of the four

53 ted into peptides using Fmoc-chemistry-based solid-phase peptide synthesis, and the resulting peptide

54 ith varying cation-pi binding energies using solid-phase peptide synthesis, and these analogues were

55 ng groups mostly adopted in the solution and solid-phase peptide synthesis, are compatible to the ado

56 Abeta(x-16), and Abeta(5-38(D23S)) by using solid phase peptide synthesis as internal standards for

57 pplications of this chemistry to reiterative solid-phase peptide synthesis as well as solid-phase fra

58 These approaches include solid-phase peptide synthesis based on an adaption of na

59 we synthesize DDMs using solution phase and solid phase peptide synthesis chemistry.

60 (Arg(11)) was synthesized using conventional solid-phase peptide synthesis chemistry and a rhenium cy

61 make our first-generation cross-linker using solid-phase peptide synthesis chemistry.

62 ng that it can be manipulated under standard solid-phase peptide synthesis conditions.

63 -ReCCMSH-Asp-OH (10), were synthesized using solid phase peptide synthesis followed by rhenium cycliz

64 These building blocks are compatible with solid-phase peptide synthesis following the 9-fluorenylm

65 s bearing amide carbonyl derivatives rely on solid-phase peptide synthesis for amide functionalizatio

66 Solid-phase peptide synthesis has been an attractive met

67 Solid-phase peptide synthesis has been applied to the pr

68 d psoriasin of 100 amino acid residues using solid phase peptide synthesis in combination with native

69 can be used as the detection method for the solid-phase peptide synthesis in combinatorial chemistry

70 acid building blocks, suitably protected for solid-phase peptide synthesis, in 2-3 steps starting fro

71 The application of microwave irradiation to solid-phase peptide synthesis increases product purity a

72 hese redox modules were incorporated through solid-phase peptide synthesis into a 13-residue helical

73 acids appropriately protected for Fmoc-based solid-phase peptide synthesis is described.

74 hniques, including the Fmoc/tBu strategy for solid phase peptide synthesis, is stable under mild acid

75 PNA synthesis employs protocols derived from solid-phase peptide synthesis, making the methodology st

76 A solid-phase peptide synthesis methodology that allows fo

77 Cys)n-NH2, n = 2-6) have been synthesized by solid-phase peptide synthesis methods and characterized

78 Using solid-phase peptide synthesis methods, two units of the

79 denotes N-isobutylglycine), were prepared by solid-phase peptide synthesis methods.

80 describe five of the main techniques, namely solid phase peptide synthesis, native chemical ligation,

81 The heterogeneous reaction medium in solid-phase peptide synthesis necessitates the use of la

82 We show here the first full stepwise solid phase peptide synthesis of mambalgin-1 and confirm

83 lar beta-sheets" are synthesized by standard solid-phase peptide synthesis of a linear precursor foll

84 nd identification of the products during the solid-phase peptide synthesis of glycine, alanine, and v

85 1 linker is applied in the manual Fmoc-based solid-phase peptide synthesis of Leu-enkephalin and in m

86 Solid-phase peptide synthesis of several flavopeptin spe

87 ation step can be carried out as part of the solid-phase peptide synthesis, or it can be undertaken i

88 ating that residue into peptides by standard solid-phase peptide synthesis procedures.

89 do-5-hydroxylysine derivative can be used in solid-phase peptide synthesis, providing access to prote

90 The conjugates were synthesized by solid-phase peptide synthesis, purified by reversed-phas

91 ed amino acid building blocks, followed by a solid-phase peptide synthesis sequence, featuring two re

92 To prove the usefulness of this strategy in solid-phase peptide synthesis, several bioactive peptide

93 alpha-Azido acids have been used in solid phase peptide synthesis (SPPS) for almost 20 years

94 4S)-methyldecanoic acid) required to support solid phase peptide synthesis (SPPS) for structure-activ

95 GlcNAc-Asn building blocks during automated solid phase peptide synthesis (SPPS), followed by orthog

96 native chemical ligation (NCL) reaction with solid phase peptide synthesis (SPPS).

97 orm for convenient use as building blocks in solid phase peptide synthesis (SPPS).

98 lysine residues, which are incompatible with solid-phase peptide synthesis (SPPS) due to the intrinsi

99 Solid-phase peptide synthesis (SPPS) is a widely used te

100 The semisynthetic approach relies on the solid-phase peptide synthesis (SPPS) of N-terminal thioe

101 They are prepared by solid-phase peptide synthesis (SPPS) or biosynthetically

102 a-Ile-Asp-Tyr-Ile-Asn-Gly-OH), following the solid-phase peptide synthesis (SPPS) protocol and Amyloi

103 The use of solid-phase peptide synthesis (SPPS) to prepare four suc

104 Solid-phase peptide synthesis (SPPS) using tert-butyloxy

105 fluorophores are directly incorporated after solid-phase peptide synthesis (SPPS) via on-resin deriva

106 lows this chelator to be incorporated during solid-phase peptide synthesis (SPPS) with total site spe

107 ted to linear thiopeptide cores prepared via solid-phase peptide synthesis (SPPS), giving an efficien

108 Gla), appropriately protected for Fmoc-based solid-phase peptide synthesis (SPPS), is described.

109 mma-glutamate 20, suitable for Fmoc-strategy solid-phase peptide synthesis (SPPS), was achieved in fo

110 ically to KTag, available via semi-automated solid-phase peptide synthesis (SPPS), while equipping th

111 Here we describe a simple and efficient Fmoc solid-phase peptide synthesis (SPPS)-based method for sy

112 dard N(alpha)-fluorenylmethoxycarbonyl-based solid-phase peptide synthesis (SPPS).

113 ell as full compatibility with standard Fmoc solid-phase peptide synthesis (SPPS).

114 osphopeptides from the crude preparations of solid-phase peptide synthesis step.

115 synthesis has been developed on the basis of solid-phase peptide synthesis techniques and is accompli

116 ently incorporated into peptides by standard solid-phase peptide synthesis techniques.

117 oresis (SDS-PAGE) with peptides produced via solid-phase peptide synthesis that correspond to the TM

118 Standard solid-phase peptide synthesis then resulted in the desir

119 ogues with a lactam linkage were prepared by solid phase peptide synthesis to explore possible biolog

120 lable starting materials and was employed in solid-phase peptide synthesis to afford the desired cycl

121 and tyrosine building blocks for Fmoc-based solid-phase peptide synthesis to allow convenient incorp

122 the theoretical methods, taking advantage of solid-phase peptide synthesis to incorporate approximate

123 Peptides are synthesized by standard solid-phase peptide synthesis to incorporate Fmoc-hydrox

124 the alpha-hemolysin (alphaHL) pore by using solid-phase peptide synthesis to make the central segmen

125 e used Fmoc (N-(9-fluorenyl)methoxycarbonyl) solid-phase peptide synthesis to prepare alpha-amino-n-b

126 tically replaced with diaminopimelate during solid-phase peptide synthesis to produce several analogu

127 onding to histone N termini were prepared by solid phase peptide synthesis using an acid labile Boc/H

128 The method is based on solid-phase peptide synthesis using 2-chlorotrityl resin

129 for introducing an N-Me group during regular solid-phase peptide synthesis using Boc protection.

130 /chymotrypsin proteolysis was synthesized by solid-phase peptide synthesis using known mixtures of na

131 ublished and conjugated to bombesin(7-14) by solid-phase peptide synthesis using standard Fmoc chemis

132 ini has been challenging in the past because solid-phase peptide synthesis usually starts from the C-

133 A preselected synthetic sequence via solid phase peptide synthesis was designed to produce 2,

134 Fmoc-protected DOTAla suitable for solid phase peptide synthesis was synthesized and integr

135 Solid-phase peptide synthesis was employed to elaborate

136 beled ADM analogues synthesized by Fmoc/t-Bu solid phase peptide synthesis were used to analyze their

137 g residues 354-375 of R2 was generated using solid-phase peptide synthesis where 354, a serine in the

138 was accomplished through the combination of solid-phase peptide synthesis with detailed liquid chrom

139 These peptides were prepared using solid-phase peptide synthesis with Fmoc alpha-amino prot