コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 ave investigated how they maintain substrate solubility.
2 both ligand complexation and increased solid solubility.
3 C, which was related to the much-enhanced QC solubility.
4 omains independently from their structure or solubility.
5 n-Sol is a web server for predicting protein solubility.
6 ar interactions, directly related to protein solubility.
7 suspension, STAT3 phosphorylation and water solubility.
8 ctivity and improved in vitro metabolism and solubility.
9 -level properties influencing expression and solubility.
10 real reservoir conditions would have on CO2 solubility.
11 lection, as well as protein localization and solubility.
12 rare mutations that improve both fitness and solubility.
13 activities with significantly improved water solubility.
14 nces in hydrogen bonding networks on mineral solubility.
15 oid gaining protein stability at the cost of solubility.
16 ater, while nitrone 4 exhibited a poor water solubility.
17 eability of the films without changing their solubility.
18 -predicted from chemical properties, such as solubility.
19 e ability to use light to change a protein's solubility.
20 as melting and sublimation temperatures, and solubility.
21 roperties such as particle size, charge, and solubility.
22 op optimized versions of 10E8 with increased solubility.
23 hydrophilic germ line counterparts increased solubility.
24 erlooked clusters because of their anomalous solubility.
25 ulmonary delivery of drugs with poor aqueous solubility.
26 l temperatures and demonstrated high aqueous solubility.
27 s that retain potency and have much improved solubility.
28 s extraction buffers to separate proteins by solubility.
29 d amide-aromatic hydrocarbon interactions by solubility.
30 and 1.3 +/- 0.22 muM, respectively) but poor solubility.
31 the role of SDS to be beneficial for protein solubility.
32 site-specific phosphorylation augmented its solubility.
33 latform for delivery of drugs with different solubilities.
34 centrations significantly greater than their solubilities.
35 eld (51.6% with 15% of moisture) and protein solubility (24.8% with 15% of moisture) with increased e
36 mpounds in BALB/c mice because of their high solubility (510 microg/ml for compound I and 82.9 microg
37 the most promising prodrugs a better aqueous solubility, a favorable hydrolysis in human and murine s
41 -oxidized oxygenated OA has the lowest water-solubility among all secondary OA factors, which agrees
43 igning soft semiconductors that exhibit high solubility and a tendency to provide stable organized st
44 es [color, porosimetry, crystallinity, water solubility and absorption, pasting properties, reconstit
48 indicated only minor differences in protein solubility and antibody binding following processing ste
49 The prepared systems improved the stability, solubility and antioxidant activity of curcumin and addi
50 into the symbiosome space would increase the solubility and availability of Fe(III) for rhizobial bac
52 cific sites in the GI tract, increasing drug solubility and bioavailability, and providing sustained
54 Hg, factors and conditions in control of the solubility and chemical speciation of Hg(II) and MeHg ne
55 se dendrimers show no toxicity and have good solubility and chemical stability in aqueous solutions.
56 er on the surface to facilitate their organo-solubility and compatibility in a liquid-crystal host.
57 in a convergent manner to better understand solubility and complexation structure/activity function
59 molecular shape impacts the tradeoff between solubility and crystallization tendencies in molecular s
60 reased crystallinity, but only WPC increased solubility and decrease the retrogradation tendency.
61 e compounds exhibited significantly improved solubility and decreased lipophilicity and were potent a
62 e allosteric modulator (PAM) with good water solubility and demonstrating consistent activity across
63 rodrugs (1a-8a and 9a-e) with higher aqueous solubility and enhanced pharmacokinetic and therapeutic
65 hange is also shown to selectively alter the solubility and film surface energy of the resulting mole
66 al the biophysical basis of enhanced protein solubility and function, we determined the crystallograp
69 membrane proteins (IMPs), where poor aqueous solubility and ionization of peptide-ligand adducts and
73 This efflux is necessary to ensure Fe(III) solubility and mobility in the apoplasm and uptake into
75 Iron (Fe) bioavailability depends upon its solubility and oxidation state, which are strongly influ
80 ty against mammalian cell lines was reduced, solubility and plasma-protein binding were improved whil
81 enhance hydrolysis included increased water solubility and polyester hydrophilicity as well as short
82 yl by pyridine or pyrimidine showed improved solubility and potency, whereas more hydrophilic side ch
83 paign was maintaining a balance between good solubility and potent cellular activity (suppression of
85 ntial structural features, aiming to improve solubility and safety without compromising activity agai
87 olyvinylpyrrolidone, due to its high aqueous solubility and solubility enhancement properties, using
88 cation is limited because of its low aqueous solubility and stability; this could be resolved by enca
91 dramatic effect on catalysis, increasing N2 solubility and the thermodynamic N2 binding affinity at
92 cognized as an effective strategy to enhance solubility and thus effectiveness in lipid based food.
93 -beta-cyclodextrin (HPbetaCD) to improve its solubility and to enable subcutaneous administration.
97 titration method enhanced this polypeptide's solubility and, with the aid of </=5D NMR, permitted the
98 MgCl2 -NaCl, which still retains high CaSiO3 solubility, and a supporting electrolyte of CaO, which f
100 series gave improvements in potency, aqueous solubility, and metabolic stability, which combined to g
102 However, the strong coupling between doping, solubility, and morphology can be harnessed to control c
103 s to improve the physicochemical properties, solubility, and off-target profile of 1, an inhibitor of
104 n quinoa protein gelation were attributed to solubility, and the flexibility of proteins secondary st
105 carotenoids, such as synergistic effects and solubility, are sometimes overlooked, and a greater numb
106 solution time under different conditions and solubility as well as content and speciation of selenium
107 n vitro IC50 (0.056 nM) and improved aqueous solubility as well as good efficacy in a mouse model of
108 n filament assembly, as assessed by a Triton solubility assay and a proximity ligation assay aiming t
109 discretely folded regions of human DISC1 via solubility assessment of tens of thousands of fragments
110 agement of disease is barred by poor aqueous solubility, bioavailability, tumour accumulation and ski
113 potency for the PCAF/GCN5 bromodomain, high solubility, cellular target engagement, and >/=18000-fol
116 ng antitumor activity but suboptimal aqueous solubility, consequently worth being further optimized.
117 show that different Abeta oligomers vary in solubility, consistent with distinct localization, and i
119 itation of fluorohydroxyapatite with reduced solubility could be one of the main factors for arrest o
122 ange in UV absorbance showed loss of protein solubility depending on heat treatments parameters.
125 but enhances the oxygen transport parameter (solubility-diffusion product) near the membrane center.
126 scribe optimized variants of 1 with improved solubility, druglike properties, and in vivo activity.
128 , GPC, color, FT-IR, DSC, thermal stability, solubility, emulsifying, foaming and antioxidant activit
129 of hydrolysis (DH), amino acid composition, solubility, emulsion and foaming properties were evaluat
130 done, due to its high aqueous solubility and solubility enhancement properties, using a MNP design pr
132 ion models were developed that could predict solubility-enhancing mutations that maintain wild-type f
133 ld observations were reproduced with generic solubility equilibrium controls on Fe(III) and Al and a
134 damage of the carbon basal plane can impart solubility, film-forming capability, and electrocatalyti
135 which we compare the predicted and measured solubilities finding a very close match, and we further
140 e, as their poor pharmacokinetic profile and solubility has prevented implementation as therapeutic a
141 ivity, color, moisture, water activity (aw), solubility, hygroscopicity, glass transition temperature
142 %) across a wide pH range in water and their solubility improved further within a vitamin-tea beverag
144 to measure the temperature dependence of gas solubilities in situ and to estimate the local enthalpy
145 available data for Escherichia coli protein solubility in a cell-free expression system, 35 sequence
146 d under ambient conditions, compared with CO solubility in a commonly used IL [Bmim][Tf2 N] (2x10(-3)
149 ersatility of selenocadmate by improving its solubility in a variety of polar and nonpolar solvents w
150 d delivery of compounds such as 19 with high solubility in aqueous media, an acceptable toxicological
151 zobenzene-based dark quencher with excellent solubility in aqueous media, which represents a superior
154 tion, the SiPcs 1-7 exhibit moderate-to-good solubility in chlorinated solvents, such as 1,2-dichloro
155 ceed the potential limits of water, (2) high solubility in nonaqueous media, and (3) high stability t
156 In both series, a dramatic enhancement of solubility in organic solvents (CH2Cl2, CHCl3) is observ
159 fact that charged clusters display a higher solubility in polar solvents than their neutral counterp
160 rugs to the inside of the eye; however, drug solubility in silicone oil is poor and release from this
162 usually involve a one-time reduction in oil solubility in the continuous medium via changing tempera
163 with an alloyed negative electrode, calcium solubility in the electrolyte is suppressed and operatin
164 ical conductivity and work function, reduced solubility in the processing solvent, and improved photo
168 production is highly dependent on Cr-mineral solubility; increasing Fe-substitution (x = 0 to x = 0.7
171 smaller than predicted variability in Hg(II) solubility is discussed in light of possible formation o
172 ; they can operate up to 75 degrees C (where solubility is enhanced) and can synthesize enantiopure T
174 The resulting solid has very low aqueous solubility (Ksp =1.0(4)x10(-8) ), which facilitates its
175 ume stability and conserved matrix compounds solubility leading to enhanced hyphenation robustness wh
176 only contains 50 times more barium than the solubility limit in calcite but also displays the rotati
180 gaps, i.e., the distance between the crystal solubility line and the liquid-liquid coexistence curve,
181 s to predict the approximate location of the solubility line of IgG antibodies with respect to their
182 PBDEs were inversely correlated with aqueous solubility [log KBC sediments(water) = -log Cw(sat) * 0.
184 10% of all single missense mutations improve solubility, matching theoretical predictions of global p
185 The developed strategy enables precise gas solubility measurements within 2-5 min compared with 4-5
187 concentrations confirm the NC concentration/solubility mediated nucleation and growth of superlattic
188 ' interaction with transitional states of F, solubility, membrane insertion kinetics, and protease se
196 ntropy-stabilized materials is the increased solubility of elements, which opens a broad compositiona
197 issues should be addressed, including a poor solubility of fatty acid and a substantial loss in the t
198 enhanced FBs and PHFBs reduction, due to the solubility of fumonisins in water during the steeping pr
199 ntly in Escherichia coli, the expression and solubility of hFGF21 were tested and optimised by fusing
200 of thermodynamic models to simulate measured solubility of Hg(II) and MeHg in different types of bore
206 xperimental data on aggregation hotspots and solubility of mutational variants of one of these antibo
210 direct and online characterization of water-solubility of organic aerosol (OA) by coupling a Particl
211 oferlin KO phenotype, the large size and low solubility of otoferlin have prohibited direct biochemic
212 simulations, cholesterol reduces the overall solubility of oxygen within the membrane but enhances th
214 bility of milk protein to bind vitamin A and solubility of protein and vitamin A as affected by compl
215 ion for 10min at 40% amplitude increased the solubility of purified kafirin from 6.5mug/mL to 173.3mu
216 h various PG to QC ratios were prepared; the solubility of QC reached 241.76mug/mL at PG/QC ratio of
218 characterized by low melting points and high solubility of rare earth elements and volatile molecules
219 x is generally and critically needed for the solubility of retrotranslocated ERAD-M intermediates.
221 erature not influence the swelling power and solubility of starch isolated from grains with brown per
222 rp there was reduction in swelling power and solubility of starches isolated of grains stored at 40 d
223 nerated radical with the Dha 'acceptor', the solubility of the alkyl halide precursors in aqueous sol
226 However, the acetylation did not affect acid solubility of the films, regardless of the amylose conte
227 a successful strategy for improving aqueous solubility of the parental drugs, determining a positive
228 were tested, MBP significantly enhanced the solubility of the protein also in the culture condition
230 tions of chaperones and client proteins, the solubility of the proteome can be increased by tuning th
232 oronic acid causing drastic reduction in the solubility of the resulting product (TPE-HgCl/TPE-HgMe)
234 bstitution (x = 0 to x = 0.75) decreases the solubility of the solid and concomitantly decreases tota
236 lock copolymer as nanoreactor, imparting the solubility of UCNPs and the tunability of film porosity
239 vides immediate information on the identity, solubility, oligomeric state, overall structure, and sta
241 play a role beyond modulating global protein solubility or stability, the thermodynamic properties of
243 ever, Symlin still has some issues including solubility, oral bioavailability and cost of preparation
244 ophilic analogues displayed improved aqueous solubility, particularly at low pH, although stability t
245 ents is the necessary interaction of two low-solubility phases-Cr(III) silicates or (hydr)oxides and
247 encapsulation in cyclodextrins (CDs) on the solubility, photostability and antifungal activities of
248 amount had biggest impacts on product water solubility, pigments degradation and yield, respectively
249 iated with the cytotoxicity, as well as poor solubility, processability, and biodegradability of thei
251 g another small molecule drug with different solubility profiles compared to risperidone; and 2) to d
254 (MMP) inhibitors that also possess favorable solubility properties has proved to be especially challe
257 tivity, surface hydrophobicity (H0), protein solubility (PS)) and emulsifying (emulsion capacity (EC)
259 s reported to date have insufficient aqueous solubility relative to their cellular potency to be comp
260 ated ERAD-M substrates is required for their solubility; removal of the polyubiquitin chains or compe
263 influence nanocolloid surface reactivity and solubility, should be considered in the context of mercu
264 PbS NC assembly (e.g., NC concentration and solubility, solvent type, evaporation rate, seed mediati
265 as ideal functional molecules to improve the solubility, stability, and bioavailability of inorganic
266 better suited due to their small size, high solubility/stability and extensive homology to human VH3
267 rion structure is tailored to decrease water solubility, stabilize emulsion droplets, and promote int
268 d the encapsulation of NO by CDs using phase solubility studies, Isothermal Titration Calorimetry, Nu
270 al efficacy in thrombosis models and aqueous solubility suitable for intravenous administration.
273 is group isolates were subjected to our bile solubility test (which measures and calculates the diffe
279 arches had higher moisture content and water solubility than the native high amylose starch film.
280 of Abeta42 is more downhill, with a computed solubility that is about 10 times smaller than that of A
281 itated by a fast computational prediction of solubility that requires only the amino acid sequence as
282 ever, almost all mutations decreased protein solubility, the most common cause of protein design fail
283 ach enabled us to diagnose an issue with TXS solubility, the resolution of which yielded a 25-fold im
284 hysicochemical properties, basically aqueous solubility, two different approaches were followed, enta
286 ers, which utilizes the reduction in polymer solubility upon p-type doping to provide direct, optical
287 ess of improving other properties (affinity, solubility, viscosity, etc.) and suggest changes at othe
293 concentrations were controlled by Ca3(VO4)2 solubility, which demonstrate an inverse relationship be
294 ruption of the crystal packing would improve solubility, which led to a change from N-methylpyridone
296 ally balances monomer, polymer, and catalyst solubility while eliminating transesterification as a de
299 distance, the nanofibers exhibit high water solubility, without any signs of intramolecular triple h
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。