戻る
「早戻しボタン」を押すと検索画面に戻ります。

今後説明を表示しない

[OK]

コーパス検索結果 (1語後でソート)

通し番号をクリックするとPubMedの該当ページを表示します
1 ave investigated how they maintain substrate solubility.
2 both ligand complexation and increased solid solubility.
3 C, which was related to the much-enhanced QC solubility.
4 omains independently from their structure or solubility.
5 n-Sol is a web server for predicting protein solubility.
6 ar interactions, directly related to protein solubility.
7  suspension, STAT3 phosphorylation and water solubility.
8 ctivity and improved in vitro metabolism and solubility.
9 -level properties influencing expression and solubility.
10  real reservoir conditions would have on CO2 solubility.
11 lection, as well as protein localization and solubility.
12 rare mutations that improve both fitness and solubility.
13 activities with significantly improved water solubility.
14 nces in hydrogen bonding networks on mineral solubility.
15 oid gaining protein stability at the cost of solubility.
16 ater, while nitrone 4 exhibited a poor water solubility.
17 eability of the films without changing their solubility.
18 -predicted from chemical properties, such as solubility.
19 e ability to use light to change a protein's solubility.
20 as melting and sublimation temperatures, and solubility.
21 roperties such as particle size, charge, and solubility.
22 op optimized versions of 10E8 with increased solubility.
23 hydrophilic germ line counterparts increased solubility.
24 erlooked clusters because of their anomalous solubility.
25 ulmonary delivery of drugs with poor aqueous solubility.
26 l temperatures and demonstrated high aqueous solubility.
27 s that retain potency and have much improved solubility.
28 s extraction buffers to separate proteins by solubility.
29 d amide-aromatic hydrocarbon interactions by solubility.
30 and 1.3 +/- 0.22 muM, respectively) but poor solubility.
31 the role of SDS to be beneficial for protein solubility.
32  site-specific phosphorylation augmented its solubility.
33 latform for delivery of drugs with different solubilities.
34 centrations significantly greater than their solubilities.
35 eld (51.6% with 15% of moisture) and protein solubility (24.8% with 15% of moisture) with increased e
36 mpounds in BALB/c mice because of their high solubility (510 microg/ml for compound I and 82.9 microg
37 the most promising prodrugs a better aqueous solubility, a favorable hydrolysis in human and murine s
38                                   A ratio of solubility (activity) difference between tree wood and o
39 ensure both analytes and matrix constituents solubility after mobile phase decompression.
40 r water stability, bulk density, and protein solubility, along with a smoother surface.
41 -oxidized oxygenated OA has the lowest water-solubility among all secondary OA factors, which agrees
42              eCF506 exhibits excellent water solubility, an optimal DMPK profile and oral bioavailabi
43 igning soft semiconductors that exhibit high solubility and a tendency to provide stable organized st
44 es [color, porosimetry, crystallinity, water solubility and absorption, pasting properties, reconstit
45      To address the trade-off between enzyme solubility and activity, we performed deep mutational sc
46  the identified lead 4ab demonstrated a good solubility and an acceptable in vivo PK profile.
47                The model returns a predicted solubility and an indication of the features which devia
48  indicated only minor differences in protein solubility and antibody binding following processing ste
49 The prepared systems improved the stability, solubility and antioxidant activity of curcumin and addi
50 into the symbiosome space would increase the solubility and availability of Fe(III) for rhizobial bac
51 means to form aoQMs, independent of the salt solubility and base strength.
52 cific sites in the GI tract, increasing drug solubility and bioavailability, and providing sustained
53 heless, its use is limited by its poor water-solubility and chemical instability.
54 Hg, factors and conditions in control of the solubility and chemical speciation of Hg(II) and MeHg ne
55 se dendrimers show no toxicity and have good solubility and chemical stability in aqueous solutions.
56 er on the surface to facilitate their organo-solubility and compatibility in a liquid-crystal host.
57  in a convergent manner to better understand solubility and complexation structure/activity function
58                        Changes in structure, solubility and content of arabinoxylan (AX) was determin
59 molecular shape impacts the tradeoff between solubility and crystallization tendencies in molecular s
60 reased crystallinity, but only WPC increased solubility and decrease the retrogradation tendency.
61 e compounds exhibited significantly improved solubility and decreased lipophilicity and were potent a
62 e allosteric modulator (PAM) with good water solubility and demonstrating consistent activity across
63 rodrugs (1a-8a and 9a-e) with higher aqueous solubility and enhanced pharmacokinetic and therapeutic
64                Thermal stability, viscosity, solubility and experimental density are determined.
65 hange is also shown to selectively alter the solubility and film surface energy of the resulting mole
66 al the biophysical basis of enhanced protein solubility and function, we determined the crystallograp
67  redox species, which exhibit relatively low solubility and inadequate redox potentials.
68                              The kinetics of solubility and ionic calcium concentration during in vit
69 membrane proteins (IMPs), where poor aqueous solubility and ionization of peptide-ligand adducts and
70          The FLI tag adds charge to increase solubility and ionization, and utilizes stable isotope l
71         However, issues surrounding the poor solubility and low stability of enzymes in truly anhydro
72                      However, poor intrinsic solubility and low to moderate oral bioavailability made
73   This efflux is necessary to ensure Fe(III) solubility and mobility in the apoplasm and uptake into
74 nzothiazole scaffold and endowed with better solubility and oral bioavailability.
75   Iron (Fe) bioavailability depends upon its solubility and oxidation state, which are strongly influ
76                           However, their low solubility and permeability make their application in th
77 ic compounds, especially for drugs with poor solubility and permeability.
78  phosphoramide prodrug (29) with an improved solubility and pharmacokinetic profile.
79 lar groups at inhibitor scaffolds to improve solubility and pharmacokinetic properties.
80 ty against mammalian cell lines was reduced, solubility and plasma-protein binding were improved whil
81  enhance hydrolysis included increased water solubility and polyester hydrophilicity as well as short
82 yl by pyridine or pyrimidine showed improved solubility and potency, whereas more hydrophilic side ch
83 paign was maintaining a balance between good solubility and potent cellular activity (suppression of
84              Although glycosylation improves solubility and renders the metabolites suitable for tran
85 ntial structural features, aiming to improve solubility and safety without compromising activity agai
86 g efficacious backup compounds with improved solubility and safety.
87 olyvinylpyrrolidone, due to its high aqueous solubility and solubility enhancement properties, using
88 cation is limited because of its low aqueous solubility and stability; this could be resolved by enca
89 icroparticles, substantially increased their solubility and swelling power.
90  a significant improvement of both the water solubility and the microsomal stability.
91  dramatic effect on catalysis, increasing N2 solubility and the thermodynamic N2 binding affinity at
92 cognized as an effective strategy to enhance solubility and thus effectiveness in lipid based food.
93 -beta-cyclodextrin (HPbetaCD) to improve its solubility and to enable subcutaneous administration.
94                                           Fe solubility and transport within and between plant tissue
95                      At 160 degrees C color, solubility and UV/Vis absorption change characteristical
96  the production of DDGS lead to an increased solubility and viscosity of water-extractable AX.
97 titration method enhanced this polypeptide's solubility and, with the aid of </=5D NMR, permitted the
98 MgCl2 -NaCl, which still retains high CaSiO3 solubility, and a supporting electrolyte of CaO, which f
99            The structural heterogeneity, low solubility, and high aggregation propensity of Ascl1 in
100 series gave improvements in potency, aqueous solubility, and metabolic stability, which combined to g
101 , M tuberculosis H37Rv), selective activity, solubility, and metabolic stability.
102 However, the strong coupling between doping, solubility, and morphology can be harnessed to control c
103 s to improve the physicochemical properties, solubility, and off-target profile of 1, an inhibitor of
104 n quinoa protein gelation were attributed to solubility, and the flexibility of proteins secondary st
105 carotenoids, such as synergistic effects and solubility, are sometimes overlooked, and a greater numb
106 solution time under different conditions and solubility as well as content and speciation of selenium
107 n vitro IC50 (0.056 nM) and improved aqueous solubility as well as good efficacy in a mouse model of
108 n filament assembly, as assessed by a Triton solubility assay and a proximity ligation assay aiming t
109 discretely folded regions of human DISC1 via solubility assessment of tens of thousands of fragments
110 agement of disease is barred by poor aqueous solubility, bioavailability, tumour accumulation and ski
111               Optimization focused mainly on solubility, brain penetration, and the search for an ami
112                                      The gas solubility can be determined by performing steady-state
113  potency for the PCAF/GCN5 bromodomain, high solubility, cellular target engagement, and >/=18000-fol
114 nal step enhanced polyphenols and flavonoids solubility coming from the fruit and fibres.
115                      Compound 35 had notable solubility compared to 29 and showed good tolerability i
116 ng antitumor activity but suboptimal aqueous solubility, consequently worth being further optimized.
117  show that different Abeta oligomers vary in solubility, consistent with distinct localization, and i
118                               Doping-induced solubility control is a patterning technique for semicon
119 itation of fluorohydroxyapatite with reduced solubility could be one of the main factors for arrest o
120 plate for analysis of further expression and solubility datasets.
121 wn that many mutations that increase protein solubility decrease catalytic activity.
122 ange in UV absorbance showed loss of protein solubility depending on heat treatments parameters.
123 -CDs provided AL type and gamma-CDs BS phase solubility diagrams.
124                                   Within the solubility-diffusion model of passive membrane permeatio
125 but enhances the oxygen transport parameter (solubility-diffusion product) near the membrane center.
126 scribe optimized variants of 1 with improved solubility, druglike properties, and in vivo activity.
127 ility after processing and their release and solubility during digestion.
128 , GPC, color, FT-IR, DSC, thermal stability, solubility, emulsifying, foaming and antioxidant activit
129  of hydrolysis (DH), amino acid composition, solubility, emulsion and foaming properties were evaluat
130 done, due to its high aqueous solubility and solubility enhancement properties, using a MNP design pr
131                                  For a given solubility-enhancing mutation, the probability that it w
132 ion models were developed that could predict solubility-enhancing mutations that maintain wild-type f
133 ld observations were reproduced with generic solubility equilibrium controls on Fe(III) and Al and a
134  damage of the carbon basal plane can impart solubility, film-forming capability, and electrocatalyti
135  which we compare the predicted and measured solubilities finding a very close match, and we further
136 ens/selections that purport to gauge protein solubility for two full-length enzymes.
137                                              Solubility (from 3 to 41%, at pH 7), emulsifying activit
138 ual domains may not be optimised for greater solubility, giving scope for fragment engineering.
139                     The powders all had high solubility (&gt;80%) across a wide pH range in water and th
140 e, as their poor pharmacokinetic profile and solubility has prevented implementation as therapeutic a
141 ivity, color, moisture, water activity (aw), solubility, hygroscopicity, glass transition temperature
142 %) across a wide pH range in water and their solubility improved further within a vitamin-tea beverag
143 ped for the rapid in situ measurement of gas solubilities in liquids.
144 to measure the temperature dependence of gas solubilities in situ and to estimate the local enthalpy
145  available data for Escherichia coli protein solubility in a cell-free expression system, 35 sequence
146 d under ambient conditions, compared with CO solubility in a commonly used IL [Bmim][Tf2 N] (2x10(-3)
147 ovides a link between anesthetic potency and solubility in a lipid-like, non-polar medium.
148 o afford materials which exhibited excellent solubility in a range of nonchlorinated solvents.
149 ersatility of selenocadmate by improving its solubility in a variety of polar and nonpolar solvents w
150 d delivery of compounds such as 19 with high solubility in aqueous media, an acceptable toxicological
151 zobenzene-based dark quencher with excellent solubility in aqueous media, which represents a superior
152 described as less efficient due to their low solubility in aqueous media.
153                     Helium has a much higher solubility in CaZrF6 than silica glass or crystobalite.
154 tion, the SiPcs 1-7 exhibit moderate-to-good solubility in chlorinated solvents, such as 1,2-dichloro
155 ceed the potential limits of water, (2) high solubility in nonaqueous media, and (3) high stability t
156    In both series, a dramatic enhancement of solubility in organic solvents (CH2Cl2, CHCl3) is observ
157 th a high chemical and thermal stability and solubility in organic solvents.
158 pophilicity (clogP = 7.1) with no measurable solubility in PBS buffer.
159  fact that charged clusters display a higher solubility in polar solvents than their neutral counterp
160 rugs to the inside of the eye; however, drug solubility in silicone oil is poor and release from this
161 iquid oil proportions resulted in higher CO2 solubility in the AMF.
162  usually involve a one-time reduction in oil solubility in the continuous medium via changing tempera
163  with an alloyed negative electrode, calcium solubility in the electrolyte is suppressed and operatin
164 ical conductivity and work function, reduced solubility in the processing solvent, and improved photo
165             Proanthocyanidins reduced gluten solubility in urea and decreased surface hydrophobicity
166            Known correlations between log D, solubility, in vitro clearance, and plasma protein bindi
167 itial conversion rate increased as substrate solubility increased.
168 production is highly dependent on Cr-mineral solubility; increasing Fe-substitution (x = 0 to x = 0.7
169 enaturation as shown by decrease in nitrogen solubility index.
170                                      Protein solubility is an important property in industrial and th
171 smaller than predicted variability in Hg(II) solubility is discussed in light of possible formation o
172 ; they can operate up to 75 degrees C (where solubility is enhanced) and can synthesize enantiopure T
173 e sequence determinants for improved protein solubility is highly desired.
174     The resulting solid has very low aqueous solubility (Ksp =1.0(4)x10(-8) ), which facilitates its
175 ume stability and conserved matrix compounds solubility leading to enhanced hyphenation robustness wh
176  only contains 50 times more barium than the solubility limit in calcite but also displays the rotati
177 oyed with SrTe well beyond its thermodynamic solubility limit of <1 mol%.
178                                          The solubility limitations of phenolic acids in many lipidic
179 prodrug designed to address dissolution- and solubility-limited absorption issues.
180 gaps, i.e., the distance between the crystal solubility line and the liquid-liquid coexistence curve,
181 s to predict the approximate location of the solubility line of IgG antibodies with respect to their
182 PBDEs were inversely correlated with aqueous solubility [log KBC sediments(water) = -log Cw(sat) * 0.
183  for vaccine development are limited by poor solubility, low yield, and protein misfolding.
184 10% of all single missense mutations improve solubility, matching theoretical predictions of global p
185   The developed strategy enables precise gas solubility measurements within 2-5 min compared with 4-5
186               Based on thermal stability and solubility measurements, it is found that GAA is more th
187  concentrations confirm the NC concentration/solubility mediated nucleation and growth of superlattic
188 ' interaction with transitional states of F, solubility, membrane insertion kinetics, and protease se
189                                  Data on the solubilities of gases in liquids are foundational for as
190 his work, we report a method to estimate the solubility of antibodies at various temperatures.
191                 Furthermore, the theoretical solubility of apigenin in the supercritical fluid system
192 erns are explained by the different apparent solubility of calcite in free drift systems.
193               This study aims to examine the solubility of CO2 in anhydrous milk fat (AMF) as functio
194                                      Aqueous solubility of copper phthalocyanine-3,4',4'',4'''-tetras
195 nd precise coverage of factors governing the solubility of different classes of polymers.
196 ntropy-stabilized materials is the increased solubility of elements, which opens a broad compositiona
197 issues should be addressed, including a poor solubility of fatty acid and a substantial loss in the t
198 enhanced FBs and PHFBs reduction, due to the solubility of fumonisins in water during the steeping pr
199 ntly in Escherichia coli, the expression and solubility of hFGF21 were tested and optimised by fusing
200 of thermodynamic models to simulate measured solubility of Hg(II) and MeHg in different types of bore
201                                      Protein solubility of hydrolysates improved (p<0.05) over a rang
202                                          The solubility of jarosite at near-neutral pH and biogeochem
203                                     With low solubility of LiF in water, this protection layer also a
204             The volatility and limited water solubility of linalool is a critical issue to be solved.
205 g advantage of the DP-dependent differential solubility of MOS in aqueous-ethanol solutions.
206 xperimental data on aggregation hotspots and solubility of mutational variants of one of these antibo
207                      This study on the water-solubility of OA factors provides insights for interpret
208                                    The water-solubility of OA factors, resolved with Positive Matrix
209               Tyrosinase greatly reduced the solubility of oat protein despite limited crosslinking.
210  direct and online characterization of water-solubility of organic aerosol (OA) by coupling a Particl
211 oferlin KO phenotype, the large size and low solubility of otoferlin have prohibited direct biochemic
212 simulations, cholesterol reduces the overall solubility of oxygen within the membrane but enhances th
213 conjugation yield likely due to the enhanced solubility of palmitic acid analog.
214 bility of milk protein to bind vitamin A and solubility of protein and vitamin A as affected by compl
215 ion for 10min at 40% amplitude increased the solubility of purified kafirin from 6.5mug/mL to 173.3mu
216 h various PG to QC ratios were prepared; the solubility of QC reached 241.76mug/mL at PG/QC ratio of
217 y of phytoglycogen (PG) to improve the water solubility of quercetin (QC).
218 characterized by low melting points and high solubility of rare earth elements and volatile molecules
219 x is generally and critically needed for the solubility of retrotranslocated ERAD-M intermediates.
220                            Due to poor water solubility of SMART compounds, co-solvent delivery is re
221 erature not influence the swelling power and solubility of starch isolated from grains with brown per
222 rp there was reduction in swelling power and solubility of starches isolated of grains stored at 40 d
223 nerated radical with the Dha 'acceptor', the solubility of the alkyl halide precursors in aqueous sol
224  tag, which might alter the localization and solubility of the associated protein.
225 ing and often dependent on the structure and solubility of the domains.
226 However, the acetylation did not affect acid solubility of the films, regardless of the amylose conte
227  a successful strategy for improving aqueous solubility of the parental drugs, determining a positive
228  were tested, MBP significantly enhanced the solubility of the protein also in the culture condition
229                           Each tag increased solubility of the protein when the expression temperatur
230 tions of chaperones and client proteins, the solubility of the proteome can be increased by tuning th
231 tion of molecular chaperones that ensure the solubility of the proteome.
232 oronic acid causing drastic reduction in the solubility of the resulting product (TPE-HgCl/TPE-HgMe)
233 amylose content, the swelling power, and the solubility of the rice flour.
234 bstitution (x = 0 to x = 0.75) decreases the solubility of the solid and concomitantly decreases tota
235 e bonds affects the structural stability and solubility of these minerals.
236 lock copolymer as nanoreactor, imparting the solubility of UCNPs and the tunability of film porosity
237  mouse model of cystinuria by increasing the solubility of urinary cystine.
238 ns provided complementary information on the solubility of V under various conditions.
239 vides immediate information on the identity, solubility, oligomeric state, overall structure, and sta
240 small enough not to significantly affect the solubility or size.
241 play a role beyond modulating global protein solubility or stability, the thermodynamic properties of
242 quantitative protein transfer, denaturation, solubility, or stability.
243 ever, Symlin still has some issues including solubility, oral bioavailability and cost of preparation
244 ophilic analogues displayed improved aqueous solubility, particularly at low pH, although stability t
245 ents is the necessary interaction of two low-solubility phases-Cr(III) silicates or (hydr)oxides and
246                                   NO aqueous solubility, photo- and thermal stability were enhanced a
247  encapsulation in cyclodextrins (CDs) on the solubility, photostability and antifungal activities of
248  amount had biggest impacts on product water solubility, pigments degradation and yield, respectively
249 iated with the cytotoxicity, as well as poor solubility, processability, and biodegradability of thei
250                                          The solubility profile of 5 in solvents commonly used for al
251 g another small molecule drug with different solubility profiles compared to risperidone; and 2) to d
252                             Based on protein solubility profiles, the optimal DSI processing conditio
253  these proteins according to their detergent solubility profiles.
254 (MMP) inhibitors that also possess favorable solubility properties has proved to be especially challe
255                             Control over the solubility properties of container molecules is a centra
256 py studies show that these solvents have the solubility properties of heptane.
257 tivity, surface hydrophobicity (H0), protein solubility (PS)) and emulsifying (emulsion capacity (EC)
258 es with different compositions and increased solubility relative to the initial solid phases.
259 s reported to date have insufficient aqueous solubility relative to their cellular potency to be comp
260 ated ERAD-M substrates is required for their solubility; removal of the polyubiquitin chains or compe
261                     However, the low aqueous solubility rendered them undesirable drug candidates.
262 ric point shift, which itself is linked to a solubility shift.
263 influence nanocolloid surface reactivity and solubility, should be considered in the context of mercu
264  PbS NC assembly (e.g., NC concentration and solubility, solvent type, evaporation rate, seed mediati
265 as ideal functional molecules to improve the solubility, stability, and bioavailability of inorganic
266  better suited due to their small size, high solubility/stability and extensive homology to human VH3
267 rion structure is tailored to decrease water solubility, stabilize emulsion droplets, and promote int
268 d the encapsulation of NO by CDs using phase solubility studies, Isothermal Titration Calorimetry, Nu
269 e determined from separation of low and high solubility subsets.
270 al efficacy in thrombosis models and aqueous solubility suitable for intravenous administration.
271                                          The solubility, swelling properties and amylose leaching of
272 and 10 protein-localization, degradation and solubility tags.
273 is group isolates were subjected to our bile solubility test (which measures and calculates the diffe
274             This study assesses a novel bile solubility test and MALDI-TOF for the differentiation of
275                           Combining the bile solubility test and the MALDI-TOF spectra results provid
276                                     The bile solubility test based on spectrophotometric reading desc
277                   Racemates often have lower solubility than enantiopure compounds, and the mixing of
278 gates displayed comparable or superior water solubility than native betaLg and betaLg/CA.
279 arches had higher moisture content and water solubility than the native high amylose starch film.
280 of Abeta42 is more downhill, with a computed solubility that is about 10 times smaller than that of A
281 itated by a fast computational prediction of solubility that requires only the amino acid sequence as
282 ever, almost all mutations decreased protein solubility, the most common cause of protein design fail
283 ach enabled us to diagnose an issue with TXS solubility, the resolution of which yielded a 25-fold im
284 hysicochemical properties, basically aqueous solubility, two different approaches were followed, enta
285  into NPM with significantly increased water solubility (up to 500 times).
286 ers, which utilizes the reduction in polymer solubility upon p-type doping to provide direct, optical
287 ess of improving other properties (affinity, solubility, viscosity, etc.) and suggest changes at othe
288                                  The highest solubility was found for E-FPC followed by A-FPC at neut
289                             As expected, CO2 solubility was found to linearly decrease with temperatu
290                                      The CO2 solubility was measured using a home-made experimental a
291                                      Minimum solubility was observed at pH 4, confirming the isoelect
292  typically polymer formulations, that change solubility when illuminated with ultraviolet light.
293  concentrations were controlled by Ca3(VO4)2 solubility, which demonstrate an inverse relationship be
294 ruption of the crystal packing would improve solubility, which led to a change from N-methylpyridone
295                  In particular, insufficient solubility, which may lead to aggregation under typical
296 ally balances monomer, polymer, and catalyst solubility while eliminating transesterification as a de
297            We predict protein expression and solubility with accuracies of 70% and 80%, respectively,
298 pigment yield ( approximately 90%) with good solubility with the least color loss.
299  distance, the nanofibers exhibit high water solubility, without any signs of intramolecular triple h
300                                      Protein solubility, zeta potential, circular dichroism and gel s

WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。
 
Page Top