ライフサイエンスコーパス: solution structure

1 ESI process, rather than a genuine memory of solution structure.

2 toxins (TFT) or from the kappa-bungarotoxin solution structure.

3 rmations only slightly more compact than the solution structure.

4 mited degree of inter-SCR flexibility in its solution structure.

5 extent electrosprayed proteins retain their solution structure.

6 at arise from a heterogeneous mixture of RNA solution structures.

7 he MD results and the experimentally derived solution structures.

8 ns initially adopt their biologically active solution structures.

9 Both a solution structure (2a) and a possible binding mode for

10 in (Ntd), which prompted us to elucidate the solution structure and activity of both the full-length

11 xperimental and computational studies on the solution structure and aggregation properties of both si

12 and potential function, we characterized the solution structure and binding distribution of the MBD3

13 Combining the solution structure and biochemical data, a model of ComA

14 The solution structure and dynamic ensembles of the duplexes

15 Here, we probe the solution structure and dynamics of active and inactive T

16 Here, we report the high-resolution solution structure and dynamics of such an active SCI.

17 ine-labeled protein were used to compare the solution structure and dynamics of wild-type and Gly64Se

18 The results provide insights into polyQ solution structure and fibril formation while also sugge

19 tational model to predict the large-scale 3D solution structure and flexibility of nucleic acid nanos

20 X-ray interferometry technique to probe the solution structure and fluctuations of B-form DNA on a l

21 search approach for getting insight into the solution structure and function of carbohydrates at all

22 in the determination of the high-resolution solution structure and further structure-function studie

23 Here we report the solution structure and in vitro activity for the cross-l

24 We report here the solution structure and mechanism of novel iron-mediated

25 The average solution structure and microscopic elasticity measured b

26 To probe the solution structure and oligomerization properties of HD5

27 The effect of lysine substitution on solution structure and on ligand binding was investigate

28 PolyQ solution structure and properties are important not only

29 s indispensable for proper function, yet its solution structure and role in catalysis remain elusive.

30 Here, we present the high-resolution solution structure and structural dynamics of the D' reg

31 small angle neutron scattering to study the solution structure and subunit organization of a holoenz

32 diferric state does not represent the frozen solution structure and that a mono-mu-hydroxo diferrous

33 mall angle x-ray scattering to determine the solution structure and to analyze the conformational fle

34 nal studies shed light on the details of the solution structures and afford a highly predictive stere

35 Our three-dimensional solution structures and biochemical analysis of DPF3b hi

36 Solution structures and biochemical data have provided a

37 s at very low temperatures aimed at defining solution structures and dynamics and some kinetic studie

38 Infrared evaluation of solution structures and multivariate analysis of the vib

39 We have determined the solution structures and thermodynamic properties of Baci

40 binding region that characterize its compact solution structure are diminished.

41 cesses, but their mechanisms of assembly and solution structures are difficult to define.

42 ons produced from modeling suggests that the solution structures are largely preserved in the gas pha

43 Here we present the first solution structures based on data from NMR spectroscopy

44 der what conditions, and to what extent, can solution structure be retained without solvent?"

45 binds to C3d and C3b, we determined the TT30 solution structure by a combination of analytical ultrac

46 e determined its monomeric three-dimensional solution structure by NMR and characterized its binding

47 We purified OmcA and characterized its solution structure by small angle x-ray scattering (SAXS

48 Furthermore, its solution structure closely matched (backbone rmsd 1.21 A

49 The solution structure confirms that PASGtYybT adopts the ch

50 rearrangement of the active site, leading to solution structures consistent with available functional

51 Small angle x-ray scattering defines solution structures consistent with the interdomain comm

52 tructures were compared to the corresponding solution structures derived from measured proton chemica

53 ormation, which is remarkably similar to its solution structure determined by NMR.

54 hia coli, solved by NMR, represent the first solution structures determined for the type III class of

55 ramolecular hydrogen bonding observed in the solution structures determined in the low-dielectric sol

56 It was found that the solution structure differs from the crystal structure in

57 We report the solution structure, dynamics, and energetics of three tr

58 ta are ubiquitous and most routinely used in solution structure elucidation, this fast and efficient

59 However, their solution-structure elucidation by NMR presents several c

60 ion and employ this to evaluate the accurate solution structure for each [LnL(1)].

61 Solution structures for antibodies are critical to under

62 g modeling revealed predominantly asymmetric solution structures for both antibodies with extended hi

63 cture was used to identify 10-12 near-planar solution structures for each of the MBL dimers, trimers,

64 ently used for heparin, we have analyzed the solution structures for eight purified HS fragments dp6-

65 tron scattering modeling revealed asymmetric solution structures for IgG4(Ser(222)) with extended hin

66 eproducibly revealed very similar asymmetric solution structures for monomeric rabbit IgG in differen

67 can lead to disparities between gaseous and solution structures for partially unfolded proteins.

68 y NMR standards (42 kDa) and illuminates the solution structure, free from crystal-packing constraint

69 actions were analyzed in the 113 crystal and solution structures from the lipocalin family.

70 for MeTr and CFeSP both free and in complex, solution structures have not been established.

71 ects, particularly the relationships between solution structure, interfacial forces, and particle mot

72 entrifugation studies confirmed that the ADC solution structure is a tetramer.

73 The solution structure is an unusual H-type pseudoknot featu

74 The NDQ10 beta-sheet solution structure is essentially identical to that foun

75 The DQ10 PPII and 2.5(1)-helix solution structure is essentially identical to that in t

76 These near-planar fan-like solution structures joined at an N-terminal hub clarifie

77 Antigen solution structures, MAIT cell activation potencies (EC5

78 The methods developed here for N-mtMCM solution structure modeling should be suitable for other

79 ns in Asp157 on heat-induced changes in PsbO solution structure, O(2) release kinetics, and PSII redo

80 1.25 A) crystal structure of proMPO and its solution structure obtained by small-angle X-ray scatter

81 NOE Rosetta program was used to generate the solution structure of a 27-kDa fragment of the Escherich

82 cinia graminis f. sp. tritici We present the solution structure of a coiled-coil (CC) fragment from S

83 Here, we report the NMR solution structure of a complex between PEP-19 and the C

84 We determined the solution structure of a complex between the AML1-ETO NHR

85 present the first nuclear magnetic resonance solution structure of a DB[a,l]P-derived adduct, the 14R

86 altered recognition, we have determined the solution structure of a DNA duplex with a 5'CalphaAG-3'

87 Here we report on the NMR solution structure of a G-quadruplex formed by the CEB1

88 solved the high resolution three-dimensional solution structure of a Gla/Hyp-containing 18-residue co

89 Here, we investigated the solution structure of a minimal lambda5-UR motif that in

90 )-microglobulin (beta(2)m), to determine the solution structure of a nonnative amyloidogenic intermed

91 Here, we report the first NMR solution structure of a photoswitchable peptide derived

92 We reveal the solution structure of a short, antiparallel, myosin-10 c

93 The solution structure of a stabilized form of the active CP

94 The solution structure of a ubiquitin-UIM fusion protein des

95 Solution structure of AbpA determined by NMR reveals a n

96 Here, we examined the solution structure of AIPL1 by small angle x-ray scatter

97 diffraction methods, were used to probe the solution structure of alpha-aryl lithium enolates of bis

98 Here, we present the solution structure of an analog of muO section sign-GVII

99 ng NMR spectroscopy, we determined the first solution structure of an interaction between eIF3 subuni

100 We report on the first solution structure of an intramolecular G-quadruplex con

101 ing was used to determine the low resolution solution structure of apo-IRP1 and to characterize its b

102 ere we report the nuclear magnetic resonance solution structure of APOBEC3A and show that the critica

103 Here, we describe the NMR-derived solution structure of apoMlcB, which displays a globular

104 The solution structure of astexin-1 was determined revealing

105 ides, astexin-2 and astexin-3, and solve the solution structure of astexin-3.

106 The pseudo-atomic solution structure of BH0236 determined by small-angle X

107 Here, we determined the NMR solution structure of Blo t 21, which represents the fir

108 Here we present the solution structure of calcium-calmodulin bound to a pept

109 nding site on CCP 1 and visualized it with a solution structure of CCPs 1-3 derived by NMR and small

110 Here, we report the solution structure of CDK2AP1 by combined methods of sol

111 To probe the response of the solution structure of Cel7A to changes in pH, we measure

112 The solution structure of complement C3b is crucial for the

113 The solution structure of covalently modified GlbN was deter

114 We have determined the solution structure of DBPA and studied DBPA's interactio

115 The solution structure of domains 18-19 showed a similar dom

116 We report the solution structure of Escherichia coli beta-galactosidas

117 Therefore, the solution structure of Escherichia coli TsaC was characte

118 and modeling clearly enabled us to infer the solution structure of FhaC, with H1 inside the pore as i

119 The solution structure of FhuA agrees with its crystal struc

120 esidues map to a beta-sheet in the published solution structure of FtsN(SPOR).

121 determined the small angle x-ray scattering solution structure of full-length IRF4, which, together

122 his work, we report the determination of the solution structure of Gfi-1 zinc fingers 3-5 in complex

123 The NMR solution structure of HD5(ox), solved at pH 4.0 in 90:10

124 olipoprotein A-I plays a central role in the solution structure of high-density lipoproteins.

125 action between HMGA2 and RFs, we studied the solution structure of HMGA2, free and in complex with RF

126 Here, we report the 3D NMR solution structure of homodimeric CC MBS in which amino

127 d in Escherichia coli, the three-dimensional solution structure of hPgn K3 was determined via NMR spe

128 we have used NMR spectroscopy to obtain the solution structure of human DYNLT1 forming a complex wit

129 The NMR solution structure of IreB was determined, revealing tha

130 The three-dimensional solution structure of KYE28 in LPS is characterized by a

131 Solution structure of LANA complexes revealed that while

132 We determined the solution structure of LEDGF PWWP and monitored binding t

133 The solution structure of LIMD2 that was determined using nu

134 To determine the solution structure of MBL, synchrotron x-ray scattering

135 Probing the solution structure of membrane proteins represents a for

136 We have determined the solution structure of mouse IL-6 to assess the functiona

137 c basis for these differences, we solved the solution structure of MVN free and in complex with its l

138 Here, we present the First low resolution solution structure of myostatin-free and myostatin-bound

139 First, we solved the solution structure of OspE by NMR, revealing a fold that

140 NMR spectroscopy was used to determine the solution structure of p68N and map its interface with th

141 Here, the solution structure of Pdc and its interaction with the 1

142 contrast variation was used to determine the solution structure of protein and lipid components of re

143 The aqueous solution structure of protoxin II (ProTx II) indicated t

144 The stability of the solution structure of rabbit IgG in different buffers an

145 Here we report the solution structure of RbpA and identify the principle si

146 The solution structure of Rbx1/ROC1 revealed a globular RING

147 We refined a three-dimensional solution structure of recombinant FH1-3 based on nuclear

148 Here we report the solution structure of SecB, a chaperone that exhibits st

149 We report here the solution structure of several repetitive DNA sequences c

150 ction at a molecular level by solving both a solution structure of Sgt2_NT, which adopts a unique hel

151 Here, we report the solution structure of sigma1.1 from the Gram-positive ba

152 The nuclear magnetic resonance (NMR) solution structure of SpoIIID in complex with DNA reveal

153 We determined the NMR solution structure of the 1:2:1 parallel-stranded loop i

154 ere we report the nuclear magnetic resonance solution structure of the 2:1 complex of XR5944 with the

155 scattering studies allow for modeling of the solution structure of the activation domain in the absen

156 The three-dimensional NMR solution structure of the allosteric site revealed an al

157 The three-dimensional solution structure of the alpha-conotoxin Lo1a was deter

158 Herein, we present the solution structure of the amino-terminal portion of mous

159 the high-affinity HM binding, we solved the solution structure of the apo form and the crystal struc

160 ort the crystal structure and low resolution solution structure of the BARPH domains of APPL2.

161 Here we describe the three-dimensional solution structure of the bilin-binding domain as Pfr, u

162 We report the NMR-derived solution structure of the Brd4 ET domain bound to a cons

163 ing NMR spectroscopy, the high-resolution 3D solution structure of the C-terminal DNA-binding domain

164 We have determined the solution structure of the C-terminal domain of human SRA

165 In addition, the dynamic 3D solution structure of the C-terminal heptapeptide of the

166 Here, we report the solution structure of the C-terminal zinc-binding domain

167 NMR spectroscopy, we have characterized the solution structure of the C-terminus of MBD1 (MBD1-c, re

168 Here we present and interpret the solution structure of the C-type lectin-like domain of N

169 company Ca(2+) binding, we have obtained the solution structure of the Ca(2+)-free protein using NMR

170 A low-resolution solution structure of the closed conformation of PKCbeta

171 Here we describe the solution structure of the complex formed by the interact

172 The solution structure of the complex of enzyme IIA of the N

173 The solution structure of the construct was determined in do

174 We reevaluated the solution structure of the CR2-C3d complex that confirmed

175 This binding surface can accommodate the 3D solution structure of the cross-linked cell wall.

176 xperimental studies are yet to determine the solution structure of the Cu site and how this relates t

177 The NMR solution structure of the d(TTGTGGTGGGTGGGTGGGT) sequenc

178 binding sites (EBS1 to -3).We solved the NMR solution structure of the d3' hairpin of the Sc.ai5gamma

179 In this work, the solution structure of the deuterated Ca(2+)-CIB1 protein

180 Here we present the NMR solution structure of the Drosophila Smo CRD, and descri

181 Indeed, our NMR solution structure of the EHD1 EH-domain in complex with

182 tidine phosphotransfer (DHp) domains and the solution structure of the entire cytosolic domain of ETR

183 ts these perturbations to be mapped onto the solution structure of the enzyme.

184 We have determined the solution structure of the FliT chaperone in the free sta

185 ils of this activity, we have determined the solution structure of the Fpr4 C-terminal PPIase domain

186 ural changes upon binding, we determined the solution structure of the free dsRBD used in the previou

187 report the nuclear magnetic resonance (NMR) solution structure of the full-length CR4/5 domain from

188 ufficient for interaction and solved the NMR solution structure of the globular domain of M2AP.

189 Here, we describe the high-resolution solution structure of the Gp2-Ec beta' jaw domain comple

190 , we present unprecedented insights into the solution structure of the Hauser base (i)Pr2NMgCl 1 and

191 tivity by cAMP/TRIP8b, we determined the NMR solution structure of the HCN2 channel CNBD in the cAMP-

192 Here we report the solution structure of the Hox homeodomain in complex wit

193 Here, we report the solution structure of the HR domain of OutC and explore

194 The nuclear magnetic resonance (NMR) solution structure of the I domain revealed the presence

195 LTag hexameric helicases, we determined the solution structure of the intact hexameric E1 helicase b

196 we have determined the three-dimensional NMR solution structure of the intracellular domain of p45 an

197 We have determined the solution structure of the isolated F1 TnC C-terminal dom

198 t the use of NMR spectroscopy to analyze the solution structure of the isolated regulatory domain of

199 The solution structure of the KvAP VSD solubilized within ph

200 Here we provide the solution structure of the latter component of the RelA:C

201 sion proteins in leukemia, we determined the solution structure of the MLL-IBD complex.

202 Unexpectedly, the solution structure of the most potent stapled peptide, D

203 We determined the solution structure of the myristoylated protein and foun

204 port on the nuclear magnetic resonance (NMR) solution structure of the N-terminal domain of betaGRP (

205 he present study, we have determined the NMR solution structure of the N-terminal ectodomain of human

206 In this work we determined the solution structure of the N-terminal portion of the MCM

207 pling (RDC) measurements to characterize the solution structure of the non-glycosylated form.

208 Here we report the solution structure of the norsolorinic acid synthase (NS

209 The solution structure of the NOXO1beta PX domain shows grea

210 Here we present the solution structure of the NPM1-C70 domain and NMR analys

211 g and x-ray crystallography, we describe the solution structure of the oligomers formed during the ir

212 The low-resolution solution structure of the open Munc18:Syntaxin binding m

213 We determined the solution structure of the PAS domain of GtYybT from Geob

214 show that IcsA is monomeric and describe the solution structure of the passenger domain obtained by s

215 Herein, we present the NMR solution structure of the phylogenetically conserved ISS

216 The solution structure of the reduced form of the MAL TIR do

217 A solution structure of the relevant LIP5-CHMP5 complex re

218 Therefore, here we investigated the solution structure of the retinoschisin monomer and the

219 We report here the solution structure of the RNA recognition motifs (RRM) d

220 Here we solve the solution structure of the RNF126 zinc finger domain in c

221 nformation compared to the unbound NMR-based solution structure of the same PG-fragment.

222 We have determined the solution structure of the Specifier Loop domain of the t

223 ronuclear, multidimensional NMR spectroscopy solution structure of the STAS domain from the SulP/SLC2

224 Furthermore, the solution structure of the switch I region is analyzed by

225 The NMR solution structure of the zinc-finger (ZnR) domain from

226 an inferred PREVIOUSLY: Here we describe the solution structure of the ZmPPR10: ATPH: complex using s

227 nsemble modeling analysis to investigate the solution structure of these linkers, extending from the

228 In this study, the solution structure of this domain was determined by smal

229 This is the first solution structure of this domain, and our investigation

230 lations show the B/P pair in the most stable solution structure of this FLP to have an unfavorable or

231 pe reconstruction provides insights into the solution structure of this previously unreported complex

232 The NMR solution structure of this trimeric domain, designated g

233 Here, we present the solution structure of TpbA in the ligand-free open confo

234 Finally, we elucidated the solution structure of TraI using small angle x-ray scatt

235 The NMR solution structure of TriA1 in dodecylphosphocholine mic

236 small-angle X-ray scattering to examine the solution structure of Trim5alpha BCC, the dimerization d

237 utron scattering (SANS) is used to probe the solution structure of two protein therapeutics (monoclon

238 hroughput scattering methods, we studied the solution structure of wild-type IgG4(Ser(222)) and a hin

239 The solution structure of YAP WW2 confirms that it has a can

240 nd (13)C NMR study was used to determine the solution structures of 1-methoxyallenyllithium.

241 structural motifs to predict the equilibrium solution structures of 45 DX-based DNA origami nanoparti

242 The solution structures of [(6)Li]-i-PrLi complexed to (-)-s

243 opy is used in this work to characterize the solution structures of bound anion receptors for the fir

244 Here, we report the solution structures of F0, F1 and of the F0F1 double dom

245 e dependence of stability, we report the NMR solution structures of five RNA duplexes: (rGACGAGCGUCA)

246 The solution structures of free Enzyme I (EI, approximately

247 Here, we present the solution structures of GDP-bound and apo-IF2-G2 of Bacil

248 The solution structures of highly active Ir water-oxidation

249 Here, we provide the solution structures of its two RNA recognition motifs (R

250 f NADPH, we have determined and compared NMR solution structures of L. casei apo DHFR and its binary

251 The solution structures of nucleocapsid (NC)-like CCHC zinc-

252 ethod (RosettaOligomers) for determining the solution structures of oligomeric systems using only che

253 We have concatenated new high-resolution solution structures of overlapping recombinant CCP pairs

254 Here we report the use of solution structures of Pol X in the free, binary (Pol X:

255 N in the absence or presence of RNAP and the solution structures of RapA and RapADeltaN either ligand

256 In this work, we present detailed solution structures of rat amylin using a combination of

257 First, NMR solution structures of reduced and Hg(2+)-bound forms of

258 directed spin labeling was used to probe the solution structures of REs involved in p53 regulation of

259 e report here high quality three-dimensional solution structures of SCP-2 from Aedes aegypti determin

260 The NMR solution structures of several of the monosaccharide-con

261 Analysis of crystal and solution structures of several of the products reveal th

262 SAXS solution structures of SNX20 and SNX21 show that these p

263 In this article, we present the crystal and solution structures of the 195-kDa C4b.

264 The solution structures of the 34-kDa apo- and holo-FepB fro

265 report the nuclear magnetic resonance (NMR) solution structures of the A20-like zinc finger (A20 Znf

266 tructures of the ASL(Arg1,2) showed that the solution structures of the ASLs were nearly identical.

267 We report the solution structures of the C-terminal UBM of human pol i

268 The solution structures of the dilithiated diamino diethers

269 We report here the solution structures of the free and arginine-bound forms

270 ic labeling ((2)H and (13)C) has allowed the solution structures of the freely exchanging major and m

271 used small-angle X-ray scattering to obtain solution structures of the full-length proteins and a se

272 the expected alpha-beta-alpha fold, but the solution structures of the major conformation of Nhp2p w

273 Furthermore, solution structures of the MLL3 core complex assembled w

274 scattering data, we report the pseudoatomic solution structures of the monomer and dimer forms of th

275 We report the first solution structures of the mouse Rev1 CTD and its comple

276 The solution structures of the phosphorylated and unphosphor

277 Solution structures of the proteins are based on NMR dat

278 Here we report crystal and solution structures of the resting and activated states

279 We solved the solution structures of the RRM in complex with poly(U) o

280 Here, we describe the solution structures of the two central complexes of the

281 Here, crystallographic and solution structures of the UVR8 homodimer, together with

282 We report the solution structures of the VPg proteins from feline cali

283 The solution structures of three mixed aggregates dissolved

284 To rectify this, we have studied the solution structures of two human IgG1 6a and 19a monoclo

285 Crystal and solution structures plus mutations characterize alternat

286 contrast to other reported PDZ domains, the solution structure previously reported for IL-16 reveals

287 ermined by small-angle x-ray scattering, the solution structures reveal a new conformation of RapA, d

288 he NMR-restrained molecular-dynamics-derived solution structure revealed that the modifications provi

289 ized and characterized in terms of their NMR solution structures, serum and thermal stabilities, and

290 The solution structures, stabilities, physical properties, a

291 tion W165T causes destabilization of protein solution structure, strongest for domain D1, which inter

292 To reveal its solution structure that underlies such a dynamic and com

293 In X-ray solution structures, the CARDs in unliganded MDA5 are fl

294 of Bc28.1 and determined its high resolution solution structure using NMR spectroscopy.

295 pressed and purified to homogeneity, and its solution structure was found to be dimeric.

296 Based on NMR and CD data, its solution structure was solved and is a long bent, interr

297 triplex maintains an excellent memory of the solution structure, well-preserved helicity, and a signi

298 Solution structures were determined by NMR, activity ass

299 High-resolution NMR solution structures were determined for one mutant and o

300 (octapa)](-) complex revealed a 7-coordinate solution structure, which forms a single isomer and exhi