ライフサイエンスコーパス: solvolysis

1 ivergence away from rearrangement and toward solvolysis.

2 ophile facilitated by a Lewis-acid-catalysed solvolysis.

3 ete mechanistic scheme for allyl carboxylate solvolysis.

4 Free R1P undergoes both C-OP and CO-P solvolysis.

5 complete esterification without substantial solvolysis.

6 ediately loses chloride ion in an S(N)1-like solvolysis.

7 C5 methyl ester modestly slowed the rate of solvolysis (1.8x, pH 3) without altering the inherent re

8 -based probes, PVSN and PVS are resistant to solvolysis and are cell-permeable and thus hold promise

9 been reflected in their faster rates of both solvolysis and enzymatic hydrolysis.

10 te, sialyl-galactose, in both acid-catalyzed solvolysis and enzymatic transfer reactions.

11 s were found to be much more reactive toward solvolysis and hydrolysis, much less effective DNA alkyl

12 It is demonstrated that solvolysis and internal return can be explained by the s

13 (2) in hydroxylic solvents proceed with both solvolysis and rearrangement.

14 2), CN, or CO(2)R) can be induced to undergo solvolysis and substitution reactions through an elimina

15 such as solubility, solvent complexation, or solvolysis, and makes the resulting process highly envir

16 Solvolysis/dehydrohalogenation rates of 2-chloro-2-methy

17 Observations of unexpected silane solvolysis distributions in the HAT-initiated hydrogenat

18 analogues proved remarkably reactive toward solvolysis even at pH 7, where the reaction is uncatalyz

19 A sequential solvolysis/hydride shift/intramolecular reduction cascad

20 motes either the formation of an N-B bond or solvolysis if 1 equiv of water is present.

21 in (PCB), was cleaved from the apoprotein by solvolysis in alcohols and alcoholic aqueous solutions.

22 The rate of solvolysis in aqueous buffer of analogue 1S was 50-fold

23 hylsilyl-endo-2-norbornyl mesylate undergoes solvolysis in CD3CO2D only 2.6 times faster than endo-2-

24 The latter undergo rapid solvolysis in hydroxylic solvents even at room temperatu

25 es dramatically accelerated 6 activation and solvolysis in methanolic solutions ("pH 7.4") compared w

26 developed here is that 1-adamantyl chloride solvolysis is assisted by hydrogen bond donation departi

27 3))(HOCH(3))), and the rate constant for its solvolysis is k(max) = 1.5 x 10(-4) s(-1).

28 ater extent than that of tert-butyl chloride solvolysis, most likely due to lessened steric interacti

29 Solvolysis of 1-(trimethylsilylmethyl)cyclopropyl mesyla

30 ain the increased sensitivity of the rate of solvolysis of 1-adamantyl chloride over tert-butyl chlor

31 lore the nature of the cations formed in the solvolysis of 2-bicyclo[3.2.1]octanyl tosylate the 2-bic

32 on has been applied to the specific rates of solvolysis of 2-phenyl-2-ketoethyl bromide and tosylate

33 Comparisons with the specific rates of solvolysis of 2-phenylethyl bromide and methyl tosylate

34 arge Et3P-mediated rate enhancements for the solvolysis of 6 compared with 13 and a N(7)-substituted

35 Solvolysis of 6-OMs and 18-OMs effected skeletal rearran

36 The rate of nonenzymatic acid-catalyzed solvolysis of 8-vinyladenine from the stem-loop RNA is d

37 is divergent synthetic approach involves the solvolysis of a transient and highly labile tertiary-pro

38 by visible light because of the photoinduced solvolysis of acetonitrile or py ligands.

39 In solvolysis of alkyl halides Hal-(CH(2))(n)-C(BCH(3))(11)

40 The solvolysis of alpha-d-glucopyranosyl fluoride in hexaflu

41 ic bromopolyene cyclization initiated by the solvolysis of an enantiomerically enriched vicinal bromo

42 dagger) vs approximated DeltarG degrees for solvolysis of benzhydryl aryl/alkyl carbonates and benzh

43 The specific rates of solvolysis of benzoyl fluoride have been determined at 2

44 The rate constants for solvolysis of CH(3)SCH(2)Cl, a model for GS-CH(2)Cl, ran

45 of KIEs is quite different than observed for solvolysis of CMP-NeuAc.

46 monium and chloronium ions are generated (by solvolysis of enantiomerically enriched precursors) and

47 The solvolysis of exo-7-isodeltacyclyl brosylate generates t

48 Solvolysis of exo-8-deltacyclyl brosylate proceeds direc

49 Solvolysis of kallolide A and isokallolide A in [(18)O]-

50 The specific rates of solvolysis of N,N,N',N'-tetramethyldiamidophosphorochlor

51 n the reaction mixtures was a Mg2+-dependent solvolysis of nerolidyl diphosphate.

52 as studied theoretically for the case of the solvolysis of norborn-2-en-7-ylmethyl-X systems by defin

53 Subsequent solvolysis of organotrifluoroborates in the presence of

54 The mechanism of the heterolytic solvolysis of p-tolyldiazonium cation in water was studi

55 By comparing the SQase-catalyzed solvolysis of PSPP in the absence of NADPH3 to the react

56 Solvolysis of pure Z-trifluoroacetate (p-CH3) gives smal

57 m is proposed involving (a) rate-determining solvolysis of RCN by THF followed by rapid oxygenation o

58 By comparison, the difference in rates of solvolysis of structurally related tosylates were nearly

59 utilized to suggest that the higher rate of solvolysis of tert-butyl chloride in aqueous ethanol is

60 Undesired solvolysis of the amide group in the side chain of Asn o

61 The solvolysis of the endo epimer presents a more complex pi

62 tylinosine by a modified Appel reaction, and solvolysis of the glycosyl linkage gave 6-(imidazol-1-yl

63 alculations of the activation free energy of solvolysis of the pyrophosphate bond in a conformational

64 Solvolysis of the S-(halomethyl)glutathione intermediate

65 Solvolysis of the urea products generates alpha-alkenyla

66 cates neighboring-group participation in the solvolysis of tosylates but not in the hydrolysis of ace

67 The solvolysis of two diastereomers may give the same two pr

68 ls-Alder reaction, which following an S(N)2' solvolysis process to displace the iodo group affords a

69 eventually trapped by water to form the sole solvolysis product 12b.

70 ported data are consistent with the retained solvolysis product being formed in an S(N)i (D(N)(++)*A(

71 eported for the reactions of 2 proceeding to solvolysis products and 3.

72 Reactions of 1 proceed to solvolysis products and both 2 and 3; since 2 slowly und

73 The ratio of cyclized to solvolysis products decreases with the increase in ring

74 vent demonstrated that the C2 alkoxyl of the solvolysis products originated from the solvent, suggest

75 e C2 hydroxyl with an alkoxyl group to yield solvolysis products that display net retention of config

76 conversion of alcohols 1 and 8 into various solvolysis products, including dimeric ethers 2 and 9, w

77 These compounds are the expected "solvolysis" products from PSPP.

78 First-order solvolysis rate constants are reported for solvolyses of

79 B) leaving groups have been derived from the solvolysis rate constants of X,Y-substituted benzhydryl

80 the following trends when compared with the solvolysis rate constants: (i) electron-rich sulfonyl ch

81 Substituents on the phenyl ring affect the solvolysis rate of benzhydryl benzoates by both field an

82 t pH 7), a pH-independent (H(+) independent) solvolysis rate profile at pH 3/4-7, and a much reduced

83 for the acyl series (RCOCl), for which both solvolysis rates and HBDEs increase in the order R = Bu

84 sis of the kinetic data and comparisons with solvolysis rates for the structurally related silphin-1b

85 Solvolysis rates of 2-trimethylsilylbenzocyclobutyl deri

86 ree triazoles have also been determined from solvolysis rates of substituted cumyl trifluoroacetates.

87 The activation parameters for the solvolysis reaction are as follows: DeltaH(++) = 81.4 +/

88 rect SN2Ar process is the best model for the solvolysis reaction for dynamic reasons, and its Gibbs f

89 pe effect (KIE) measurements, the TS for the solvolysis reaction in hexafluoro-2-propanol, we synthes

90 step in the formation of photo-Favorskii or solvolysis reaction products in water.

91 The transition state for the solvolysis reaction was modeled computationally using th

92 ontrolling the temperature and pressure of a solvolysis reaction.

93 benzhydrylium ion (Ph)2CH(+), even though in solvolysis reactions (80% aqueous ethanol at 25 degrees

94 hylsilyl-anti-7-norbornyl triflate undergoes solvolysis reactions 1.8 x 10(4) faster than 7-norbornyl

95 3-diarylalyl cations are generated faster in solvolysis reactions and also react faster with nucleoph

96 en shown to undergo clean pseudo-first-order solvolysis reactions in DMSO-d(6) to give products deriv

97 of this reaction to the Winstein scheme for solvolysis reactions is noted.

98 Complete Gibbs energy profiles for the solvolysis reactions of benzhydryl fluorides are constru

99 In solvolysis reactions, all of these processes follow firs

100 uoromethanes) were prepared and subjected to solvolysis reactions, which were followed conductometric

101 anions led to ultrafast half-lives for these solvolysis reactions.

102 tance of external and internal return in the solvolysis reactions.

103 A study of the solvolysis reactivity and regioselectivity of N-BOC-C5-C

104 th 2 and 3; since 2 slowly undergoes further solvolysis, specific rates are obtained by a modified Gu

105 here benzoyl chloride also shows bimolecular solvolysis, the appreciable k(Cl)/k(F) values are propos

106 t with imidazoles at C6 followed by glycosyl solvolysis to provide 2-chloro-6-(substituted-imidazol-1

107 rom classical physical-organic chemistry and solvolysis to self-assembly and supramolecular chemistry

108 rgies of transfer of the tert-butyl chloride solvolysis transition state is that there is no change i

109 ucts of the 2-bicyclo[3.2.2]nonanyl tosylate solvolysis were found to have nonclassical structures.

110 Compound 1 is inert to solvolysis with alcohols, even at elevated temperatures,