ライフサイエンスコーパス: somatic cell reprogramming

1 ation along with active transcription during somatic cell reprogramming.

2 ferentiation (TD) is a recent advancement in somatic cell reprogramming.

3 ripotency of embryonic stem cells (ESCs) and somatic cell reprogramming.

4 ternative splicing regulatory network during somatic cell reprogramming.

5 he DKC1 complex in stem cell maintenance and somatic cell reprogramming.

6 t signaling has been implicated in promoting somatic cell reprogramming.

7 sed translation of p21, a known inhibitor of somatic cell reprogramming.

8 epair-related molecular mechanisms affecting somatic cell reprogramming.

9 understand the molecular pathways governing somatic cell reprogramming.

10 s of modeling of dementia disorders based on somatic cell reprogramming.

11 r embryonic stem cell (ESC) self-renewal and somatic cell reprogramming.

12 nisms controlling stem cell pluripotency and somatic cell reprogramming.

13 al derivation of embryonic stem cells or via somatic cell reprogramming.

14 stablishing ground state pluripotency during somatic cell reprogramming.

15 an epigenetic barrier during the process of somatic cell reprogramming.

16 repression presents a roadblock to efficient somatic cell reprogramming.

17 no p53 activity favors the entire process of somatic cell reprogramming.

18 for the maintenance of ESC self-renewal and somatic cell reprogramming.

19 issecting mechanisms of ESC pluripotency and somatic cell reprogramming.

20 tional induction at pluripotency loci during somatic cell reprogramming.

21 enerate them from embryonic stem cells or by somatic cell reprogramming.

22 SETSIP) was indentified to be induced during somatic cell reprogramming.

23 owed the examination of mechanisms governing somatic cell reprogramming.

24 lation of self-renewal, differentiation, and somatic cell reprogramming.

25 s hsa-miR-302b and hsa-miR-372 promote human somatic cell reprogramming.

26 s pluripotency factors with the capacity for somatic cell reprogramming.

27 the maintenance of ES cell self-renewal and somatic cell reprogramming.

28 govern self-renewal and differentiation and somatic cell reprogramming.

29 ruppel-like factor 4 (Klf4) is essential for somatic cell reprogramming.

30 Pluripotency can be recreated by somatic cell reprogramming.

31 ction is recapitulated in the culmination of somatic cell reprogramming.

32 iation and, conversely, acts as a barrier to somatic-cell reprogramming.

33 Somatic cell reprogramming also has been achieved more r

34 pluripotency, because its depletion inhibits somatic cell reprogramming and blastocyst development.

35 enhancers in biological processes including somatic cell reprogramming and guided differentiation.

36 e isolation of true hiPSCs immediately after somatic cell reprogramming and involves column-based pos

37 mental genes, cell differentiation, stem and somatic cell reprogramming and response to environmental

38 as FBXL10) controls stem cell self-renewal, somatic cell reprogramming and senescence, and tumorigen

39 drive cellular plasticity in the context of somatic cell reprogramming and tumorigenesis.

40 ly chromatin remodeler, in ESC self-renewal, somatic cell reprogramming, and blastocyst development.

41 onal regulator in embryonic stem (ES) cells, somatic cell reprogramming, and cancer.

42 Finally, Rif1 acts as a barrier during somatic cell reprogramming, and its depletion significan

43 ects of RNA metabolism, the roles of RBPs in somatic cell reprogramming are poorly understood.

44 ctivation of the pluripotency network during somatic cell reprogramming by exogenous transcription fa

45 evelopment in vitro and, increasingly due to somatic cell reprogramming, cellular and molecular mecha

46 Somatic cell reprogramming, directed differentiation of

47 Because somatic cell reprogramming during induced pluripotent st

48 ers of nine transcription factors, including somatic cell reprogramming factors (Oct4, Sox2, Klf4, an

49 nces in stem and progenitor cell biology and somatic cell reprogramming for applications directed to

50 7 depletion compromises ESC self-renewal and somatic cell reprogramming, globally increases m(6)A RNA

51 Somatic cell reprogramming has generated enormous intere

52 ming block of cell intermediates and enables somatic cell reprogramming in absence of otherwise essen

53 enhanced the ability of ES cells to initiate somatic cell reprogramming in heterokaryons.

54 Nanog enables somatic cell reprogramming in serum-free medium suppleme

55 MicroRNAs (miRNAs) are critical to somatic cell reprogramming into induced pluripotent stem

56 ently discovered an unexpected phenomenon of somatic cell reprogramming into pluripotent cells by exp

57 Somatic cell reprogramming involves epigenomic reconfigu

58 of induced pluripotent stem cells (iPSCs) by somatic cell reprogramming involves global epigenetic re

59 These findings indicate that somatic cell reprogramming is associated with marked inc

60 Patient-specific somatic cell reprogramming is likely to have a large imp

61 tors modulate this process and contribute to somatic cell reprogramming is not clear.

62 hromatin architecture is reconfigured during somatic cell reprogramming is poorly understood.

63 how Klf4 regulates ES cell self-renewal and somatic cell reprogramming is still poorly understood.

64 licated in bypass of cellular senescence and somatic cell reprogramming, is markedly overexpressed in

65 the comprehension of the complex process of somatic cell reprogramming, many questions regarding the

66 Somatic cell reprogramming may afford models of nonfamil

67 However, during somatic cell reprogramming, mesenchymal-epithelial trans

68 ompromised both pluripotency in ES cells and somatic cell reprogramming of fibroblasts to induced plu

69 whether such abnormalities are intrinsic to somatic cell reprogramming or secondary to the reprogram

70 tablishment of early epigenetic marks during somatic cell reprogramming: Parp1 functions in the regul

71 we describe an early and essential stage of somatic cell reprogramming, preceding the induction of t

72 or cytoskeletal remodeling in modulating the somatic cell reprogramming process.

73 in-specific protease 26 negatively regulates somatic cell-reprogramming process by stabilizing chromo

74 Even though different methods of somatic cell reprogramming result in stem cell lines tha

75 further enhanced global demethylation during somatic cell reprogramming (SCR) of hHFCs.

76 The advent of somatic cell reprogramming technologies-which enables th

77 temporarily arrested in mitosis can support somatic cell reprogramming, the production of embryonic

78 Somatic cell reprogramming to a pluripotent state contin

79 The recent description of somatic cell reprogramming to an embryonic stem (ES) cel

80 Although somatic cell reprogramming to generate inducible pluripo

81 of DNA double-strand breaks, is required for somatic cell reprogramming to induced pluripotent stem c

82 d analysis to identify kinases that regulate somatic cell reprogramming to iPSCs.

83 Somatic cell reprogramming to pluripotency requires an i

84 luripotency of embryonic stem cells, and for somatic cell reprogramming to the pluripotent state.

85 udy we found that during the early stages of somatic cell reprogramming toward a pluripotent state, s

86 Directed somatic cell reprogramming, which does not pass through

87 critical importance of the NHEJ pathway for somatic cell reprogramming, with a major role for LIG4 a