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1 tem that metabolizes the hexitol D-glucitol (sorbitol).
2 were negative for L-rhamnose and D-glucitol (sorbitol).
3 enome), and biochemical tests (trehalose and sorbitol).
4 ose and trehalose) and polyols (glycerol and sorbitol).
5 r blackberry samples contained no detectable sorbitol).
6 yeasts to overproduce xylitol, mannitol, and sorbitol.
7 interleukin-1beta, but not by ansiomycin or sorbitol.
8 is decreased by increasing concentrations of sorbitol.
9 ts), including sodium chloride, sucrose, and sorbitol.
10 ictive temperature by the osmotic stabilizer sorbitol.
11 ed a major contribution to JNK activation by sorbitol.
12 th induced by environmental staurosporine or sorbitol.
13 athways in addition to converting glucose to sorbitol.
14 hydrogen from ethylene glycol, glycerol, and sorbitol.
15 ng alcohols, including converting glucose to sorbitol.
16 tissues that accumulate large quantities of sorbitol.
17 M) containing 50 mg/mL dispase II and 100 mM sorbitol.
18 than twofold after exposure to hyperosmolar sorbitol.
19 od pressure (ABP) than equi-osmotic mannitol/sorbitol.
20 se cells in media containing 1 m NaCl or 2 m sorbitol.
21 re rescued by osmotic stabilization with 1 m sorbitol.
22 uronal discharge frequency than equi-osmotic sorbitol.
23 ith sodium chloride, potassium chloride, and sorbitol.
24 ge and ABP than icv infusion of equi-osmotic sorbitol.
25 rogenase, the key enzyme for biosynthesis of sorbitol.
26 sure to high concentrations of congo red and Sorbitol.
27 ng species such as hemoglobin, fructose, and sorbitol.
28 esponse than infusion of hypertonic mannitol/sorbitol.
29 d that the product of the LXR4 reaction is D-sorbitol.
30 zes the conversion of L-xylo-3-hexulose to D-sorbitol.
31 include galactitol, L-xylo-3-hexulose, and d-sorbitol.
32 PVP but the same sense in the presence of D-sorbitol.
33 in urea, and this effect was counteracted by sorbitol.
34 plemented with either NaCl (0.4 or 0.5 m) or sorbitol (0.8 or 1.0 m) enhanced the subsequent growth o
35 sorbitol, 1,3:2,4-bis-O-(p-methylbenzylidene)sorbitol, 1,3:2,4-bis-O-(3,4-dimethylbenzylidene)sorbito
36 larifying agents (1,3:2,4-bis-O-(benzylidene)sorbitol, 1,3:2,4-bis-O-(p-methylbenzylidene)sorbitol, 1
37 pple leaf tissue exposed to exogenous [(14)C]sorbitol, [(14)C]Suc, or (14)CO(2) did not accumulate ra
40 oreover, the API was able to form films when sorbitol (30% (w/w)) was used as plasticizer and to form
41 1 from osmotically stressed HEK cells (0.2 M sorbitol; 30 min) revealed a persistent, 3.9 +/- 0.4-fol
42 ple plants were silenced or up-regulated for sorbitol-6-phosphate dehydrogenase by using the CaMV35S
44 fructose and formate, and overexpression of sorbitol-6-phosphate dehydrogenase in lactate dehydrogen
49 lective uptake in S. aureus and E. coli; and sorbitol, accumulating only in E. coli None accumulated
50 mice also exhibited an impressive defect in sorbitol accumulation (88 +/- 9% less than wild type, p
52 to NO donors also inhibited AR and prevented sorbitol accumulation in rat aortic vascular smooth musc
53 schemia-induced AR activation and myocardial sorbitol accumulation in rat hearts subjected to global
54 o-L-arginine methyl ester (L-NAME) increased sorbitol accumulation in the aorta of nondiabetic and di
55 th L-arginine did not inhibit AR activity or sorbitol accumulation in the tissues of nondiabetic anim
56 or of NO synthesis, enhanced AR activity and sorbitol accumulation in tissues of nondiabetic rats.
58 When incubated ex vivo with high glucose, sorbitol accumulation was increased by L-NAME and preven
60 hypothesis that these sugars (trehalose and sorbitol) act primarily as stress protectants for protei
66 vising against concomitant administration of sorbitol, an osmotic cathartic used to prevent SPS-induc
68 rbinil prevented AR-mediated accumulation of sorbitol and abrogated the infarct-sparing effect of lat
70 re distinct with respect to motility and the sorbitol and beta-glucuronidase markers appear to have d
72 d by PcSOT1 and PcSOT2 plays a major role in sorbitol and dry matter accumulation in sour cherry frui
74 coupled with the strain's ability to ferment sorbitol and express beta-glucuronidase have complicated
75 when compared with rats, did not accumulate sorbitol and fructose in the retina and were protected f
77 ted cataract development, normalized retinal sorbitol and fructose, and protected the retina from abn
78 n +/- SD) showed increased retinal levels of sorbitol and fructose, attenuation of GFAP immunostainin
79 described (IC50, 1 nM; ED90 vs sciatic nerve sorbitol and fructose, respectively, 0.8 and 4.0 mg/kg).
84 tol have a tendency toward self-association; sorbitol and most other nonrenal osmolytes have a relati
85 components, decreased activation of OSR1 by sorbitol and reduced activity of the OSR1 substrate, the
89 the molecule, whereas for larger osmolytes, sorbitol and sucrose, Deltax(u) remains the same as that
90 accumulation of two cryoprotective polyols, sorbitol and threitol, is integral to the extraordinary
92 tions were modulated using ligands (glucose, sorbitol and trehalose) and a thickener (maltodextrin).
93 We found that protecting osmolytes such as sorbitol and trimethylamine N-oxide can counteract the d
94 ind that two unrelated protective osmolytes, sorbitol and trimethylamine-n-oxide, function by margina
95 ormulations showed a variety of crystalline (sorbitol) and amorphous (sucrose, trehalose) structures,
97 ydration increased inner medullary inositol, sorbitol, and betaine concentrations in vivo by 85 +/- 1
98 umulation of the organic osmolytes inositol, sorbitol, and betaine in cultured mouse medullary inters
100 /- 5, 66 +/- 15, and 81 +/- 9% for inositol, sorbitol, and betaine, respectively, p < 0.05) by pretre
102 luxes for sodium chloride, ammonium sulfate, sorbitol, and galactose are used to calculate droplet wa
103 s can bind OSR1, block activation of OSR1 by sorbitol, and prevent the OSR1-induced enhancement of io
105 ning flies on media containing NaCl, KCl, or sorbitol, and that this hypersensitivity is completely r
106 were osmotically challenged with 100-200 mm sorbitol, and the intranuclear distribution of nucleolin
107 cally sucrose, but not glucose, mannitol, or sorbitol, antiAtGLR1.1 seeds did not germinate, but germ
111 itol, 1,3:2,4-bis-O-(3,4-dimethylbenzylidene)sorbitol) are presented for the native and trimethylsily
115 mixture of ethylglycerol, gulonolactone, and sorbitol (at 10, 1, and 1 mg/mL, respectively, in the in
116 e electron ionization mass spectra for three sorbitol-based nuclear clarifying agents (1,3:2,4-bis-O-
117 here is the mass spectral identification of sorbitol-based nuclear clarifying agents (NCAs) and the
119 ein hydrolysate (FPH-2, FPH-8) or 8% sucrose-sorbitol blend (SuSo) were compared to control NAM befor
120 ter cryoprotection compared to an 8% sucrose-sorbitol blend, and a stabilizing effect of FPH on myosi
121 Millimolar added K(+), but not Na(+) or sorbitol, blocks the initiation or continuation of mutan
122 in organ culture increased the production of sorbitol by a degree similar to that observed in the rat
125 nce of these transporters and the high fruit sorbitol concentrations suggest that there is an apoplas
127 increased aldose reductase activity, higher sorbitol content and less accumulation of the toxic meta
129 ves for the real-time monitoring of sucrose, sorbitol, d-glucose and d-fructose concentrations gave u
130 uencies for real-time monitoring of sucrose, sorbitol, d-glucose and d-fructose concentrations is rep
131 plied to the elaboration of biosensors for D-sorbitol, D-glucose and L-lactate with using D-sorbitol
132 bling system based on 1,3:2,4-dibenzyldene-D-sorbitol (DBS) derivatives which form gels as the pH is
133 ibed to be a potential negative regulator of sorbitol dehydrogenase (SDH) in hippocampal cells, we ex
134 disclosed hypothesis centered on the role of sorbitol dehydrogenase (SDH) in the second step of the p
137 acological inhibition of aldose reductase or sorbitol dehydrogenase blocked JAK2 and STAT5 activation
138 and pharmacology efforts to provide a potent sorbitol dehydrogenase inhibitor (SDI) as a tool to prob
141 rbitol, D-glucose and L-lactate with using D-sorbitol dehydrogenase, D-glucose dehydrogenase and L-la
142 led and found to be a selective inhibitor of sorbitol dehydrogenase, with excellent pharmacodynamic/p
145 mined the kinetic parameters of mannitol and sorbitol dehydrogenases encoded in the yeast genome, sho
150 hat hyperosmotic stress signaling induced by sorbitol disrupts the Ran protein gradient and reduces t
153 Binding studies of sugar alcohols mannitol, sorbitol, erythritol, adonitol, arabitol, galactitol, an
154 sses chosen, arsenite, hydrogen peroxide and sorbitol, exert their effects in quite different ways.
155 apoptosis induced by exogenous agents (e.g., sorbitol, Fas ligand, and BAD protein) or replication-in
156 ss of physiological characteristics, such as sorbitol fermentation ability and beta-glucuronidase pro
157 Escherichia coli (EHEC) O157:H7 that are non-sorbitol fermenting (NSF) and beta-glucuronidase negativ
158 tor, enteropathogenic E. coli (EPEC) O55:H7 (sorbitol fermenting [SOR(+)] and beta-glucuronidase posi
159 cally similar to the O157:H7 serotype as non-sorbitol fermenting and negative for beta-glucuronidase
160 pO157 (>90,000 bp), whereas closely related sorbitol-fermenting (SF) E. coli O157:H(-) strains carry
161 ed that the loss of motility in these German sorbitol-fermenting (SF) O157 strains is due to a 12-bp
163 logenetic relationship to populations of non-sorbitol-fermenting, beta-glucuronidase negative O157:H7
164 tinct subpopulations of the contemporary non-sorbitol-fermenting, beta-glucuronidase-negative O157:H7
165 polyols (glycerol, mannitol, erythritol, and sorbitol), five amino acids (glycine, alanine, sarcosine
167 es such as poly(vinylpyrrolidone) (PVP) or D-sorbitol, form ring-banded spherulites composed of hande
169 tions (8-12GPa compared to 0.05-11GPa), with sorbitol formulations showing a bimodal distribution of
170 trations of mannitol, sucrose, trehalose and sorbitol from 1:1 to 30:1 with carboxymethylcellulose (C
172 nder six well-studied conditions: high salt, sorbitol, galactose, pH 8, minimal medium and nystatin t
175 motic stress induced by the organic osmolyte sorbitol, heat shock, ultraviolet irradiation, oxidative
176 j 30, Span 20, Ecosurf EH-3, polyoxyethylene sorbitol hexaoleate, and R-95 rhamnolipid) were evaluate
178 both PGA1 and PGE1 reduced the formation of sorbitol in an ex-vivo model of diabetic cataract to an
179 s at 4 degrees C in 15 mg/mL dispase II with sorbitol in defined keratinocyte serum-free medium (KSFM
180 ide (NO) donors prevent ex vivo synthesis of sorbitol in erythrocytes obtained from diabetic or nondi
181 We also suggest that apple leaves transport sorbitol in high concentrations to avoid the feedback li
182 ermination of glucose, fructose, sucrose and sorbitol in leaf and/or apple peel samples from nine app
183 articularly partitioning and accumulation of sorbitol in sink tissues, we have cloned two sorbitol tr
185 one) and a pathological stress (hyperosmolar sorbitol) in Xenopus laevis oocytes, a cell type that is
186 nd glucose plateaued at the fourth week, but sorbitol increased 40% to the seventh harvest week.
187 anion cells did not plasmolyze even in 1.2 M sorbitol, indicating that solute accumulates in the phlo
191 ratinocyte growth, and to cellular stresses (sorbitol-induced hyperosmotic shock, UV irradiation, and
192 Hyperosmotic stress caused by NaCl, LiCl, or sorbitol induces an immediate and short duration ( appro
194 locatable photosynthate in Rosaceae species, sorbitol is a widespread compatible solute and cryoprote
195 accumulation of polyols such as xylitol and sorbitol is associated with MI depletion in diabetic com
196 he exclusion limit for Cx46 channels whereas sorbitol is at the exclusion limit for Cx32E(1)43 channe
198 We further characterize the impacts of NaCl, sorbitol, KCl and alkaline pH stresses on the cellular p
199 potent oral activity in normalizing elevated sorbitol levels and, more significantly, fructose levels
202 ct plating of dilutions of bovine feces onto sorbitol MacConkey agar containing cefixime and tellurit
203 ess treated at a tertiary care center, i.e., sorbitol-MacConkey (SMAC) agar culture, enzyme immunoass
204 E. coli O157 can be detected by culture with sorbitol-MacConkey agar (SMAC), but non-O157 STEC cannot
205 d with LD-PCR findings in 25 (89%) of the 28 sorbitol-MacConkey agar culture-negative STEC cases.
206 ts (n = 132) were randomized: controls (G1) (sorbitol/maltitol), or combinations giving xylitol 3.44
208 furfural, 5-hydroxymethylfurfural, xylitol, sorbitol, mannitol, and gluconic acid as biorefinery pla
209 ased expression of MIOX, which is induced by sorbitol, mannitol, and xylitol in a porcine renal proxi
210 e hypothesize that osmolytes such as urea or sorbitol may modulate PC1 mechanical properties and may
211 th single PSAC patch-clamp recordings and in sorbitol-mediated osmotic lysis measurements, confirming
212 rowth of sto1 mutant plants on NaCl, but not sorbitol, medium was associated with a reduction in both
214 ogenase on a surface support displaying poly(sorbitol methacrylate) chains resulted in approximately
217 reated with various organic osmolytes, e.g., sorbitol, myoinositol, and glycerolphosphoryl-choline an
218 mmonly used stress-inducing agents mannitol, sorbitol, NaCl, and hydrogen peroxide impact shoot growt
219 lates of the M. fortuitum third biovariant D-sorbitol-negative group and porcine strains of M. porcin
220 solates of the M. fortuitum third biovariant sorbitol-negative group, of which 48 (70%) had the same
221 c transporters with similar affinities (K(m) sorbitol of 0.81 mM for PcSOT1 and 0.64 mM for PcSOT2).
226 t it is resistant to molar concentrations of sorbitol or KCl, indicating that it has normal osmoregul
227 wing in medium that is not supplemented with sorbitol or NaCl, providing evidence that transcription
228 g cell integrity with the osmotic stabilizer sorbitol or via genetic suppression with the kre5(W1166X
229 with NaCl, an equi-osmolar concentration of sorbitol, or ABA, whereas AtNHX5 transcript abundance in
230 w in the presence of trimethoprim plus added sorbitol parallels the catalytic efficiency of the DHFR
231 hyperglycemia, the mice displayed augmented sorbitol pathway activity in the peripheral nerve, as we
233 is, doses that completely inhibit increased sorbitol pathway activity) is an effective approach for
235 without diabetes, suggesting a role for the sorbitol pathway and the potential for ARIs to reduce in
236 oses that partially and completely inhibited sorbitol pathway hyperactivity) arrested diabetes-induce
240 n glycolysis, pentose phosphate pathway, and sorbitol pathway, which may further exacerbate oxidative
243 mutagenesis of RMC26 produced defects in the sorbitol phosphotransferase system that prevented the tr
244 ing strategies of two species that transport sorbitol (Plantago major and apple [Malus domestica]), a
246 acterium fortuitum third biovariant complex (sorbitol positive), isolates of M. mageritense are likel
248 hondrial uncoupler), muscle contraction, and sorbitol (producing hyperosmolar shock) did not increase
250 me) with saline or various cell impermeants (sorbitol, raffinose, trehalose, gluconate, and polyethyl
251 lls with the non-permeant solutes sucrose or sorbitol, rapidly and robustly stimulated endogenous foc
252 ociated with a weakened cell wall, including sorbitol-remedial temperature sensitivity and sensitivit
254 omeostasis, but had no effect on the NaCl or sorbitol sensitivity of the osmotic hypersensitive hog1D
255 er), 1, 3, 5, 10, 20 and 30% w/w glycerol or sorbitol solution for 24h and adjusting the moisture con
260 zation signal reporter protein revealed that sorbitol stress decreases the rate of nuclear import.
264 MAO), sarcosine, betaine, proline, glycerol, sorbitol, sucrose, trehalose, and urea, using cyclic gly
265 ents with 154 mM NaCl and either 0 or 300 mM sorbitol suggested that the changes in light scattering
267 inhibition of the CWI pathway by addition of sorbitol, suppresses the ER inheritance defect in the pt
268 ic 'Greensleeves' apple trees with decreased sorbitol synthesis had abnormal stamen development, a de
269 SAGE: PpeS6PDH gene is postulated to mediate sorbitol synthesis in flower buds of peach concomitantly
270 in the acetate buffer solution containing 5% sorbitol than in the acetate buffer solution with 200-mM
272 orodeoxysorbitol ((18)F-FDS) is an analog of sorbitol that is reported to be freely filtered at the r
273 in; however, a premixed suspension of SPS in sorbitol, the only preparation stocked by many hospital
274 that they discriminate between mannitol and sorbitol to a much higher degree than the transporters.
279 Hyperosmotic stress, produced by addition of sorbitol to the incubation buffer, increased p38 phospho
280 of rat brain slices, produced by addition of sorbitol to the incubation buffer, produced prolonged ph
281 ing effective turgor pressure by addition of sorbitol to the media significantly accelerates early st
282 nimals or humans and no evidence that adding sorbitol to the resin increases its effectiveness as a t
284 viously for parasite-induced anion currents, sorbitol transport in infected RBCs was found to be sens
285 sorbitol in sink tissues, we have cloned two sorbitol transporter genes (PcSOT1 and PcSOT2) from sour
287 VA and MEP reprogrammed upon osmotic stress (sorbitol treatment) in Arabidopsis (Arabidopsis thaliana
288 lutamic Acid, m- Erythritol, D-Melezitose, D-Sorbitol) triggered the fungal metabolism in the co-inoc
292 .49 g/kg dry mass [DM], respectively), while sorbitol was predominant in leaves (40.66 g/kg DM).
295 sotonic to 154 mM NaCl by supplementing with sorbitol were progressively more transparent as NaCl inc
300 t two major hexitols in nature, mannitol and sorbitol, with moderate affinities, by a facilitative me
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