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   1 " "fruit," "burnt," "spices," "flower," and "sour").                                                 
     2  qualities (sweet, bitter, umami, salty, and sour).                                                  
     3 ncluding sugars, bitter compounds, NaCl, and sour.                                                   
     4 y traits classified as sweet, sweet-sour and sour.                                                   
     5 categories such as sweet, salty, bitter, and sour.                                                   
     6 ted to the subset of taste cells that detect sour.                                                   
     7 e identity of cells that respond directly to sour (acid) tastants has only been inferred from recordi
  
     9 itter, sweet, umami (amino acid), salty, and sour (acid), are detected by animals as diverse as fruit
    10 otonin (5-HT) in response to the presence of sour (acidic) tastants and this released 5-HT activates 
  
  
  
    14 thresholds for detection of salt, sweet, and sour and for recognition of bitter, salt, sweet, and sou
  
  
  
  
    19 in juice qualities in different sweet, sweet-sour and sour cultivars, grown in California, compared w
  
  
  
  
  
    25  detectors of sweet, bitter, umami, salt and sour, and recapitulate the molecular differentiation pro
    26 rmulas (HCFs), which have pronounced bitter, sour, and savory tastes compared with breast milk (BM) a
    27 rons, bitter TRCs to bitter neurons, sour to sour, and so on), we examined how new connections are sp
  
  
  
    31 scription of functional genes may supplement sOUR based assays as early warning indicators of upsets 
    32 bility to taste; that is, to perceive sweet, sour, bitter and salty sensations via CN VII, IX, and X.
    33 our of the five basic taste qualities-sweet, sour, bitter and umami-are mediated by separate taste-re
    34 g of the five primary flavors (sweet, salty, sour, bitter, and savory) has been extensively studied, 
  
  
  
  
    39  central integration of taste (salty, sweet, sour, bitter, umami), retronasal olfaction (i.e. smellin
    40 ctic, acetic, propionic and butyric acids in sour cassava starch wastewater using reversed-phase high
    41 e created genetically modified mice in which sour cells were marked by expression of YFP under the co
    42 entify acid-sensitive conductances unique to sour cells, we created genetically modified mice in whic
  
    44  was to optimize the vacuum-drying of frozen sour cherries in order to preserve health-beneficial phy
  
  
  
    48     Genistein compounds in twelve commercial sour cherry (Prunus cerasus L.) cultivars grown in Hunga
  
    50 l transporter genes (PcSOT1 and PcSOT2) from sour cherry (Prunus cerasus) fruit tissues that accumula
  
    52 tural pollen-part and stylar-part mutants in sour cherry along with other natural S-haplotype mutants
    53 prevalence of non-functional S-haplotypes in sour cherry but not in sweet cherry (a diploid) suggests
    54 etected in black and green tea, sour cherry, sour cherry concentrate, kefir (a fermented milk drink) 
  
  
  
  
    59 el demonstrating that the breakdown of SI in sour cherry is due to the accumulation of a minimum of t
  
    61 E) and green tea extract (GTE) were added to sour cherry juice concentrates (SCJCs) to enhance the co
    62 meric anthocyanin content of eleven types of sour cherry juice obtained from different varieties of s
  
    64 rthermore, we demonstrate that heteroallelic sour cherry pollen is self-incompatible, which is counte
  
    66 lic compounds were assessed in the following sour cherry puree by LC-MS-QTof analysis, before and aft
    67 ompounds, antioxidant activity and colour of sour cherry puree supplemented with different natural sw
  
    69 of strawberry, American cranberry, bilberry, sour cherry, black grape, orange, and apple, were analys
    70 in could be detected in black and green tea, sour cherry, sour cherry concentrate, kefir (a fermented
  
  
  
  
  
  
  
  
    79 lbit and two conventional crude oils, medium sour composite and mixed sweet blend, to developing zebr
  
    81 h soft and semi-hard cheeses, butter, cream, sour cream, buttermilk, yoghurt and low-fat milk always 
  
  
    84 qualities in different sweet, sweet-sour and sour cultivars, grown in California, compared with Wonde
  
  
  
    88 onjunction with specific oxygen uptake rate (sOUR) for nitrifying enrichment cultures exposed to diff
    89 100 g(-1) of edible portion of the sweet and sour fruits, and 84.8+/-0.2 to 87.2+/-0.2 g 100 g(-1) fo
  
    91 austively compile the existing literature on sour gas sweetening and to identify promising areas for 
  
    93 g and testing our understanding of reservoir-souring generation, prevention, and remediation processe
  
    95   We find that most tarsal sensilla harbor a sour GRN that is specifically activated by carboxylic an
    96 ablish that IR25a and IR76b are essential in sour GRNs of females for oviposition preference on acid-
  
  
  
  
   101  changes to the specific oxygen uptake rate (sOUR) in the absence and presence of Cu ions and CuNPs. 
  
  
   104 c ablation experiments have established that sour is detected by a subset of taste cells that express
   105  have been reported to be raised (bitter and sour), lowered (salt), or unchanged (sweet) in obese adu
  
   107 eatures such as consistency, stale odor, and sour odor, increased their intensity during storage.    
  
   109 Desulfovibrio vulgaris Hildenborough, cause "souring" of petroleum reservoirs through produced sulfid
  
  
  
  
  
   115 p33 gene was required to systemically infect sour orange and lemon trees, whereas either the p33 or t
   116 pring of previously admixed individuals, but sour orange is an F1 hybrid of pure C. maxima and C. ret
  
   118 ntial citrus species, Citrus macrophylla and sour orange, revealed that in the more-susceptible host 
   119 nome and mandarin, pummelo, sweet-orange and sour-orange genomes--and show that cultivated types deri
   120 , salty (p < 0.005), bitter (p < 0.005), and sour (p< 0.001) during radiation therapy that were resto
   121 ed the pheromone system of the gonochoristic sour paste nematode Panagrellus redivivus, which produce
   122 express the protein PKD2L1, which is not the sour receptor but nonetheless serves as a useful marker 
   123 aste transduction have been hindered because sour responsive cells represent only a small fraction of
  
   125 ently unknown transducer elements underlying sour, salt, and other taste qualities, given the staged 
  
  
   128 n taste modalities in humans: sweet, bitter, sour, salty and umami (the taste of monosodium glutamate
   129  five basic taste modalities: sweet, bitter, sour, salty and umami (the taste of monosodium glutamate
   130 ptual qualities (e.g., sweet, umami, bitter, sour, salty) are detected by dedicated subpopulations of
  
  
  
  
  
  
   137 ste receptor cells, we demonstrated that the sour-sensing cells act as the taste sensors for carbonat
   138 ose (sweet), caffeine (bitter), citric acid (sour), sodium chloride (salty) and monosodium glutamate 
  
   140 g these methods, we report that responses to sour stimuli are not mediated by Na(+) permeable channel
  
  
  
  
  
   146 release 5-HT directly in response to acidic (sour) stimuli and indirectly in response to bitter and s
  
   148 n times to four basic taste qualities (salt, sour, sweet, and bitter) and found that certain taste qu
   149 robial control, which is usually required in sour systems, may be counterproductive under these condi
  
  
  
   153 el suggests a mechanism for amplification of sour taste and may explain why weak acids that produce i
  
   155  samples were prepared to resemble the sweet/sour taste balance of juice from mandarin oranges in whi
   156 singly, acid sensitivity is not conferred on sour taste cells by the specific expression of Kir2.1, b
   157 rescent protein, we previously reported that sour taste cells from circumvallate papillae in the post
   158 itive proton conductance that is specific to sour taste cells has been shown to be the initial event 
  
  
   161 KIR2.1 as the acid-sensitive K(+) channel in sour taste cells using pharmacological and RNA expressio
   162 dification generates excitatory responses in sour taste cells, which can be attributed to block of a 
  
   164  these findings suggest that transmission of sour taste information involves communication between Ty
  
  
  
  
  
  
  
  
  
  
   175 (TRCs) that were previously suggested as the sour taste sensors also mediate taste responses to water
  
   177 t to differentiate between events related to sour taste transduction per se and unrelated effects of 
  
   179 on profiling and confirm its contribution to sour taste with tissue-specific knockout of the Kcnj2 ge
  
   181 ique set of taste cells largely dedicated to sour taste, and they indicate that both pH/proton concen
  
  
  
  
  
   187 s widely believed to be a receptor for acid (sour) taste in mammals on the basis of its physiological
  
  
   190 n contrast, gustatory detection of salty and sour tastes may involve direct gating of sodium channels
   191 ate significantly more savory-, bitter-, and sour-tasting and plain cereals than did the BM or MF gro
  
   193 weet neurons, bitter TRCs to bitter neurons, sour to sour, and so on), we examined how new connection
  
   195  for recognition of bitter, salt, sweet, and sour, together with a higher overall median gustatory sc
  
  
  
   199 blish a correlation between this current and sour transduction, we examined its distribution by patch
  
   201 ental taste qualities (sweet, bitter, salty, sour, umami) are sensed by dedicated taste cells (TCs) t
  
  
   204  in transducing stimuli reported as salty or sour, whereas the second messenger systems cyclic AMP an
  
  
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