ライフサイエンスコーパス: spaceflight

1 blem identified in the past decade of manned spaceflight.

2 icate that CMV may further reactivate during spaceflight.

3 seline values, was also found 10 days before spaceflight.

4 bone ECM and osteoblast cell shape occur in spaceflight.

5 45 days before and within 2 h after a 17 day spaceflight.

6 trix accumulation after growth activation in spaceflight.

7 based bed rest can serve as a model of human spaceflight.

8 considered the greatest human health risk of spaceflight.

9 ar system of the astronauts before and after spaceflight.

10 sponse that was induced during the course of spaceflight.

11 ing that tolerance induction was impaired by spaceflight.

12 f sleep-promoting drugs was pervasive during spaceflight.

13 ormation of this biofilm architecture during spaceflight.

14 t diminished vasoconstrictor responses after spaceflight.

15 ppression of immune function observed during spaceflight.

16 vations in brain blood flow may occur during spaceflight.

17 irment of visual acuity in astronauts during spaceflight.

18 molecular basis for how organisms respond to spaceflight.

19 n-microbe interactions may be altered during spaceflight.

20 ted measures ANOVA), but not during or after spaceflight.

21 nd possibly even improved, by short-duration spaceflight.

22 cantly from preflight values during or after spaceflight.

23 were not different before, during and after spaceflight.

24 ward fluid shift and axial body unloading of spaceflight.

25 lenge of upright tilt and were unaffected by spaceflight.

26 2) during tilt after spaceflight than before spaceflight.

27 ciceptors is preserved during short duration spaceflight.

28 sa was monitored in constant darkness during spaceflight.

29 anges of confluent human fibroblast cells in spaceflight.

30 ealth and well-being during future long-term spaceflights.

31 ound in urine samples from astronauts before spaceflight (10.6%) than in urine from the healthy contr

32 were not different before, during, and after spaceflight (41 +/- 4, 38 +/- 5 and 46 +/- 6 bursts min(

33 light (6.09 h [0.67]), in the 11 days before spaceflight (5.86 h [0.94]), and during the 2-week inter

34 ons obtained significantly less sleep during spaceflight (6.09 h [0.67]), in the 11 days before space

35 eek interval scheduled about 3 months before spaceflight (6.41 h [SD 0.65]) compared with in the firs

36 96 h [0.56] obtained), in the 11 days before spaceflight (7.35 h [0.51], 6.04 h [0.72]), and about 3

37 ], 6.04 h [0.72]), and about 3 months before spaceflight (7.40 h [0.59], 6.29 h [0.67]) compared with

38 upright tilt were smaller after than before spaceflight (absolute, -4 +/- 3 cm s(-1) after versus -1

39 e findings represent the first evidence that spaceflight affects community-level behaviors of bacteri

40 Spaceflight also reduced arterial ryanodine receptor-3 m

41 headward fluid shifting in microgravity, as spaceflight analogues.

42 caffeine were reduced immediately following spaceflight and 1 d postflight.

43 tional unloading was achieved during orbital spaceflight and following unilateral sciatic neurotomy.

44 V reactivation occurred in astronauts before spaceflight and indicate that CMV may further reactivate

45 Experimental mice destined for spaceflight and mice that remained on the ground receive

46 uring the prolonged isolation of exploration spaceflight and the need to ensure maintenance of circad

47 n culture (FTOC), we examined the effects of spaceflight and vector-averaged gravity on T cell develo

48 dio-acceleration during standing than before spaceflight, and in some, orthostatic hypotension and pr

49 sks of a dysregulated immune response during spaceflight are important to understand as plans emerge

50 otential was observed in measurements of the spaceflight bulk agar.

51 nic cultures of microbes have indicated that spaceflight can lead to increases in growth and virulenc

52 We tested the hypothesis that spaceflight causes changes in microRNA (miRNA) expressio

53 rmine whether the roots of plants exposed to spaceflight conditions may be experiencing hypoxia.

54 increased vulnerability to infection during spaceflights dating back to Apollo and Skylab.

55 n has been demonstrated in astronauts during spaceflights dating back to Apollo and Skylab; this coul

56 In conclusion, 17 days of spaceflight decreased force and increased shortening vel

57 is study, we tested the null hypothesis that spaceflight does not impair human baroreflex mechanisms.

58 hese results may have implications for human spaceflight, e.g., a Mars mission, and clinical medicine

59 ave illuminated fundamental issues regarding spaceflight effects on plant growth and development.

60 In the history of manned spaceflight, environmental monitoring has relied heavily

61 Moreover, the biofilms formed during spaceflight exhibited a column-and-canopy structure that

62 Spaceflight experiments over the past few decades have r

63 Spaceflight exposure appears to effect a hypoxic respons

64 ADH activity increased by 89% as a result of spaceflight exposure for both CHROMEX-03 and -05 experim

65 ere grown in agar medium during 6 or 11 d of spaceflight exposure on shuttle missions STS-54 (CHROMEX

66 The authors report that prenatal spaceflight exposure shapes vestibular-mediated behavior

67 suggest that after a total period of 43 h of spaceflight FN transcription, translation, or altered ma

68 Exposure to spaceflight for 16 days resulted in a loss of precursors

69 ular distensibility greater in arteries from spaceflight group (SF) mice (n=7) relative to ground-bas

70 examined medication use during long-duration spaceflights (>30 d).

71 yte activation with mitogenic lectins during spaceflight have shown a dramatic inhibition of activati

72 In this study, we tested the hypothesis that spaceflight impairs cerebral autoregulation.

73 Spaceflight imposes numerous adaptive challenges for ter

74 signaling is impaired in spaceflight or that spaceflight inappropriately induces Adh/GUS activity for

75 Collectively, spaceflight-induced reductions in myogenic vasoconstrict

76 The neural correlates of spaceflight-induced sensorimotor impairments are unknown

77 een MTRR 66 and SHMT1 1420 polymorphisms and spaceflight-induced vision changes.

78 to address specifically the possibility that spaceflight induces the plant hypoxia response and to as

79 ndbreaking flight will be the longest rodent spaceflight investigation and the first to explore the e

80 Spaceflight is known to diminish bone mass and reduce im

81 educed growth response in lymphocytes during spaceflight is linked to apoptosis.

82 We conclude that sleep quality during spaceflight is not degraded by sleep-disordered breathin

83 how that immune tolerance may be impaired in spaceflight, leading to excessive inflammatory responses

84 sympathetic nervous system occurring during spaceflight may be responsible for these postflight alte

85 ring the first 24 h of activation using both spaceflight microgravity culture and a ground-based mode

86 vous system and neuromuscular function after spaceflight might contribute to this problem.

87 It seems likely that alterations in spaceflight mission operations (schedule-shifting and li

88 Medication use during spaceflight missions was similar to that noted on the Sp

89 sleep aids was about 10 times higher during spaceflight missions.

90 uts on both short-duration and long-duration spaceflight missions.

91 We conclude that after 16 days of spaceflight, muscle sympathetic nerve responses to uprig

92 Any mission involving prolonged human spaceflight must be carefully planned to minimize vulner

93 ne (n = 6), 2) ground control (n = 12) or 3) spaceflight (n = 12).

94 that the impaired vasoconstriction following spaceflight occurs through the ryanodine receptor-mediat

95 ases in growth and virulence, the effects of spaceflight on biofilm development and physiology remain

96 s study investigated the effects of a 14-day spaceflight on bone mass, density and microarchitecture

97 In summary, the effect of spaceflight on bone microarchitecture in ovariectomized

98 , investigating the effects of long-duration spaceflight on CBT at rest and during exercise are clear

99 Understanding the effects of spaceflight on microbial communities is crucial for the

100 p quality in space, we studied the effect of spaceflight on sleep-disordered breathing.

101 ght experiments and to assess the effects of spaceflight on the growth and function of a model muscul

102 The effects of spaceflight on the infectious disease process have only

103 Effects of spaceflight on the muscles of the murine shoulder.

104 ngs (PSGs) from five healthy subjects before spaceflight, on four occasions per subject during either

105 Upon return from spaceflight or resumption of normal posture after bed re

106 al hypoxia response signaling is impaired in spaceflight or that spaceflight inappropriately induces

107 g lower body suction were significant before spaceflight (P < 0.05, repeated measures ANOVA), but not

108 t apex, no apex staining was observed in the spaceflight plants.

109 trix is a factor in causing these changes in spaceflight, quiescent osteoblasts were launched into mi

110 This is the first report that spaceflight regulates miRNA expression.

111 Many spaceflight-related medication uses (at least 10%) were

112 t hypoxia response and to assess whether any spaceflight response was similar to control terrestrial

113 Spaceflight resulted in lower cortical bone accrual in t

114 increase in ADH activity associated with the spaceflight roots was realized by a 28% decrease in oxyg

115 es are largely unknown, particularly for the spaceflight (SF) microgravity environment.

116 Two of 4 astronauts studied during spaceflight shed CMV in urine.

117 tudy was to test the hypothesis that 13 d of spaceflight [Space Transportation System (STS)-135 shutt

118 beats min(-1), P = 0.002) during tilt after spaceflight than before spaceflight.

119 Prolonged human spaceflight to another planet or an asteroid will introd

120 Spaceflight triggers long-term neuroplastic changes refl

121 when astronauts return to Earth: after brief spaceflight, up to two-thirds are unable to remain stand

122 Spaceflight was observed to increase the number of viabl

123 and STS-135, and the biofilms formed during spaceflight were characterized.

124 e formation of the novel architecture during spaceflight were observed to be independent of carbon so

125 soleus fibre diameter and function following spaceflight were similar to those observed after 17 days

126 anges in microbial virulence associated with spaceflight which may impact the probability of in-fligh

127 The success of interplanetary human spaceflight will depend on many factors, including the b