ライフサイエンスコーパス: spatial memory

1 gnificant deficits in object recognition and spatial memory.

2 eral assays related to episodic, working and spatial memory.

3 al neurons is a key component of working and spatial memory.

4 -term potentiation and hippocampus-dependent spatial memory.

5 episodic memory generally but to allocentric spatial memory.

6 to the processing of wake and SWS-associated spatial memory.

7 VGF knock-out mice have impaired fear and spatial memory.

8 may be associated with improvement in visual-spatial memory.

9 directly mediated actions of inflammation on spatial memory.

10 ocampus, which could account for deficits of spatial memory.

11 normal performance in hippocampus-dependent spatial memory.

12 splay impairments in contextual learning and spatial memory.

13 is that are linked to age-related decline in spatial memory.

14 on in hippocampal long-term potentiation and spatial memory.

15 ecially important for spatial processing and spatial memory.

16 deleted mice, which also display deficits in spatial memory.

17 IC1a is not required for hippocampal LTP and spatial memory.

18 for the maintenance of reactivated long-term spatial memory.

19 ficits and dysfunction in working memory and spatial memory.

20 activity, and object placement, a measure of spatial memory.

21 l septum alters hippocampal theta rhythm and spatial memory.

22 otentiation and causes selective deficits in spatial memory.

23 sure did not significantly impair adolescent spatial memory.

24 al role in various cognitive tasks including spatial memory.

25 d deficits in synaptic plasticity but not in spatial memory.

26 eurons from FUS toxicity and preserved rats' spatial memory.

27 ribution of the ReRh to the persistence of a spatial memory.

28 brain glucose uptake, GLUT4 expression, and spatial memory.

29 tion deficits and impaired context-dependent spatial memory.

30 bnormal REM sleep propensity and deficits in spatial memory.

31 p, is essential for the proper expression of spatial memory.

32 on measures of immediate and delayed visual spatial memory.

33 e iCA1-->mPFC pathway deactivation disrupted spatial memory.

34 working memory but did not affect long-term spatial memory.

35 ith the strength of the sigmoidal pattern in spatial memory.

36 CTNNB1 in parvalbumin-interneurons enhanced spatial memory.

37 four conceptually different dynamic maps of spatial memory.

38 , including episodic memory, navigation, and spatial memory.

39 receptor to regulate object recognition and spatial memory.

40 overty predicts deficits in adult short-term spatial memory.

41 rhinal region improved the accuracy of human spatial memory.

42 wed treated eFSE rats to encode and retrieve spatial memories.

43 n and/or retrieval of precise contextual and spatial memories.

44 on and therefore prevents them from encoding spatial memories.

45 r encoding or storing long-term, associative spatial memories.

46 and in the encoding of hippocampal-dependent spatial memories.

47 and are associated with the consolidation of spatial memories.

48 or ethanol challenge, followed by a test of spatial memory 30 min after administration.

49 ppocampal ACSS2 expression impairs long-term spatial memory, a cognitive process that relies on histo

50 SF) to understand how resource selection and spatial memory affect space use of feral hogs (Sus scrof

51 activation in turn prevented impairments in spatial memory after RSD but did not prevent deficits in

52 lammatory cytokine production and subsequent spatial memory alteration.

53 y considered crucial substrates of long-term spatial memory, although their precise role remains unce

54 opeptidase (IRAP) enhance fear avoidance and spatial memory and accelerate spatial learning in a numb

55 Echolocating bats have excellent spatial memory and are able to navigate to salient locat

56 Significant improvements in immediate spatial memory and driving performance were observed aft

57 Depolarization of MECII impaired spatial memory and elicited drastic changes in CA1 place

58 ce [5-7] in the spatial domain to compromise spatial memory and evaluated the impact of adding an olf

59 The modest impairments in spatial memory and hippocampal long-term potentiation di

60 Testing spatial memory and hippocampal long-term potentiation re

61 histone acetylation, and display deficits in spatial memory and impaired contextual fear extinction.

62 entorhinal cortex (mEC) plays a key role in spatial memory and is one of the first areas to express

63 from dorsal hippocampal networks involved in spatial memory and navigation to neocortical networks in

64 In mammals, spatial memory and nonspatial memory depend upon the hip

65 We found that mutants exhibited improved spatial memory and reduced anxiety.

66 n an area implicated in long-term multimodal spatial memory and representation, even in the absence o

67 ed fear conditioning and have impairments in spatial memory and sensory gating.

68 hort term, low-dose BPA exposure on anxiety, spatial memory and sucrose preference in adolescent rats

69 he previously demonstrated erasure of stored spatial memory and the disruption of place cell firing a

70 mice were impaired in locomotor activity and spatial memory and were resistant to seizure induction.

71 n more demanding tasks that assess long-term spatial memory and working memory.

72 play a role in the offline consolidation of spatial memories, and in the generation of vivid percept

73 KO) exhibit defects in synaptic plasticity, spatial memory, and increased anxiety-related behaviors-

74 scent development increases anxiety, impairs spatial memory, and increases sucrose consumption indepe

75 on system, we investigated anxious behavior, spatial memory, and metabolic functions of conditional k

76 phisticated behaviors relating to predation, spatial memory, and visual recognition comparable to tho

77 ampus computes diverse information involving spatial memory, anxiety, or reward and directly projects

78 model, hippocampal place fields that support spatial memories are abnormal at old age (7-9 months) wh

79 Olfactory and spatial memory are resistant to interference from the ad

80 Recognition and spatial memory are typically associated with the perirhi

81 Both directional coding and flexible use of spatial memory are upended, however, when a rat has to f

82 These deficits coincided with impaired spatial memory, as measured in water maze tasks.

83 number of background strains and found that spatial memory assayed by the water maze and contextual

84 els in both cortical regions, the effects on spatial memory, assessed by spontaneous alternation, wer

85 sed reactivation events toward replaying the spatial memory associated with that cue.

86 e the spatial specificity of place cells and spatial memories at vastly different running speeds.

87 ronic study, IL-1Ra-TBI mice showed improved spatial memory at 4 months post-injury.

88 the ReRh in the long-term consolidation of a spatial memory at the system level.

89 lexibility and diversity have been linked to spatial memory, attention and task performance, the cell

90 ylase inhibitor vorinostat not only restored spatial memory, but also exerted antiinflammatory action

91 ed G-1 from enhancing object recognition and spatial memory, but the ERK inhibitor U0126 did not.

92 nd of Broca (MSDB) have been associated with spatial memory, but the relationship between the two neu

93 prefrontal cortex, are important for rodent spatial memory, but their potential role in executive fu

94 Hippocampal neurons encode spatial memories by firing at specific locations.

95 d Physarum polycephalum constructs a form of spatial memory by avoiding areas it has previously explo

96 In the dentate gyrus - a key component of spatial memory circuits - granule cells (GCs) are known

97 r basal conditions and impaired retention of spatial memory compared with control mice.

98 ted place-cell reactivations are crucial for spatial memory consolidation during sleep and rest.

99 and neuronal morphology lead to a deficit in spatial memory consolidation.

100 s in CA1 long-term synaptic potentiation and spatial memory consolidation.

101 ishment in CD3zeta(-/-) mice did not restore spatial memory defects, suggesting that the cognitive de

102 +) microglial activation correlates with the spatial memory deficit and spread of tau pathology in th

103 the acute compensation of EC lesion-induced spatial memory deficit before a slower glutamatergic rei

104 TgCRND8 mice exhibited spatial memory deficits and altered anxiety that were re

105 s old) rescued the early contextual fear and spatial memory deficits and decreased subsequent plaque

106 virus-mediated PGRN overexpression prevented spatial memory deficits and hippocampal neuronal loss in

107 roaggregant Tau transgenic mice restores the spatial memory deficits and normalizes the basic synapti

108 ing of APP/PS1 transgenic mice fully rescues spatial memory deficits and synaptic depletion, without

109 d, in a large sample of wild sea lions, that spatial memory deficits are predicted by the extent of r

110 A53T mice also exhibit spatial memory deficits at 6 and 12 months, as demonstra

111 (+/+) mice had a reduced survival, developed spatial memory deficits at 6 months and motor impairment

112 t acute stresses, which might be relevant to spatial memory deficits described in posttraumatic stres

113 We show that 14 prevents manifestation of spatial memory deficits in chimeric EcoHIV-infected mice

114 R192Q mice showed significant spatial memory deficits in contextual fear-conditioning

115 548G>T(KI/KI);Psen2(-/-) mice exhibited mild spatial memory deficits in the Morris water maze task.

116 ocampal inflammatory processes contribute to spatial memory deficits in the rodent social defeat mode

117 y found that daily scheduled feeding rescued spatial memory deficits in these arrhythmic animals.

118 aE9 mice that preceded previously identified spatial memory deficits in this model.

119 ion of S6K1 improved synaptic plasticity and spatial memory deficits, and reduced the accumulation of

120 e model of Alzheimer's disease, JM6 prevents spatial memory deficits, anxiety-related behavior, and s

121 cluding sensory disturbances, and verbal and spatial memory deficits, not only in complicated HSP but

122 athology in the aged mice was accompanied by spatial memory deficits.

123 t that is crucial for correct performance in spatial memory-dependent tasks.

124 The extent to which navigational spatial memory depends on hippocampal integrity in human

125 However, the extent to which navigational spatial memory depends on hippocampal integrity in human

126 o enhance hippocampal object recognition and spatial memory depends on rapid activation of extracellu

127 Our data suggest that olfactory and spatial memory draw on independent working memory system

128 subsequent ripple-mediated consolidation of spatial memory during sleep.

129 tual memory during aversive conditioning and spatial memory during spontaneous exploration.

130 n hippocampal acetylcholine (ACh) efflux and spatial memory during tasks that varied in memory demand

131 ute stresses, with potential implications to spatial memory dysfunction in, for example, posttraumati

132 This implies that spatial memory effects in the medium with a heterogeneou

133 iences, hogs were able to discriminate among spatial memories encoded at different circadian phases o

134 ug-place preference, showing that recoding a spatial memory engram can alleviate associated maladapti

135 ns with the allatostatin system occludes the spatial memory enhancement.

136 consolidation in other circuits, results in spatial memory enhancements.

137 Spatial memory enhances an organism's navigational abili

138 Our data show that spatial memory enhances the organism's ability to naviga

139 gh dose caused bees to make more and earlier spatial memory errors and take longer to complete the ta

140 Verbal and spatial memory, executive function, attention, blood pre

141 rments of synaptic plasticity and defects in spatial memory exhibited by the Alzheimer's disease mode

142 Nestin-Cre mice exhibit a severe deficit in spatial memory extinction, whereas acquisition and long

143 a antagonist LY367385 blocked the object and spatial memory facilitation induced by E2, PPT, and DPN,

144 d inflammatory pain and opioid medication on spatial memory for a well-learned task in male Sprague-D

145 we found that TMS to the right OPA impaired spatial memory for boundary-tethered, but not landmark-t

146 condition placed a greater demand on visual-spatial memory for motion extrapolation, and thus partic

147 the MT1-MMP cytoplasmic domain in imprinting spatial memory for podosome reformation via assembly in

148 on of retinotopic to egocentric mappings, 2) spatial memory for the purposes of medium-term inhibitio

149 cal role of Crtc1-dependent transcription on spatial memory formation and provide the first evidence

150 ilarly propose that the known sparing of new spatial memory formation depends on the sparing of new m

151 t DBS of the entorhinal cortex (EC) enhances spatial memory formation in normal (wild-type) mice.

152 n vivo, and have deleterious consequences on spatial memory formation.

153 ) of the hippocampus, a region important for spatial memory formation.

154 ry for the action of cannabinoids on LTP and spatial memory formation.

155 ry inputs, long-term potentiation (LTP), and spatial memory formation.

156 self-stress regulation on the development of spatial memory function in Long-Evans hooded rats, we sh

157 ring showed a novelty-induced enhancement in spatial memory function, whereas for mothers with poor s

158 implicated in hippocampal CA3 cell-dependent spatial memory functions that likely rely on dynamic cel

159 Spatial memory, hippocampal long-term potentiation, and

160 as long been implicated in both episodic and spatial memory, however these mnemonic functions have be

161 r1 KO) mice, an animal model of FXS, exhibit spatial memory impairment and synapse malfunctioning in

162 e effect against beta-amyloid (1-40)-induced spatial memory impairment in mice.

163 y provides a new murine model of WNV-induced spatial memory impairment, and identifies a potential me

164 y heterozygous BDNF Val66Met females exhibit spatial memory impairment, regardless of acute stress.

165 city in vivo, resulting in hyperactivity and spatial memory impairment.

166 aberrant encoding of spatial information and spatial memory impairment.

167 oring the novel arm of the Y maze because of spatial memory impairments (P < .05).

168 nimals (both male and female) displayed mild spatial memory impairments and disrupted cingulate netwo

169 1beta-HSD1 deficient mice are protected from spatial memory impairments with aging, but the underlyin

170 e deposition, as well as contextual fear and spatial memory impairments.

171 s alone do not fully explain ethanol-induced spatial memory impairments.

172 did not alter dose-dependent ethanol-induced spatial memory impairments.

173 -guided focused ultrasound treatments led to spatial memory improvement in a Tg mouse model of AD Alz

174 A wide variety of insects use spatial memories in behaviours like holding a position i

175 inhibition of DeltaFosB signaling, improves spatial memory in a mouse model of AD.

176 impairments of pattern separation-associated spatial memory in AD mice are in part caused by degenera

177 s related to poorer attention, cognition and spatial memory in controls and people with PD for single

178 nd CA1 dendritic and/or spine morphology and spatial memory in female rats.

179 Disruptions in circadian timing impair spatial memory in humans and rodents.

180 nt a role for hippocampus in nonnavigational spatial memory in macaques and demonstrate the efficacy

181 ed with the Y5R are involved in retention of spatial memory in male and female mice.

182 duced alterations in synaptic plasticity and spatial memory in male rats.

183 regulates histone acetylation in neurons and spatial memory in mammals.

184 n protein synthesis, synaptic plasticity and spatial memory in mice that express familial Alzheimer's

185 Spatial memory in mice was impaired enduringly after acu

186 pal proliferation, leading to improved adult spatial memory in mice.

187 f hippocampal volume and impairment in adult spatial memory in mice.

188 navigation across species, but its role for spatial memory in nonnavigational tasks is uncertain.

189 agonist G-1 enhanced object recognition and spatial memory in ovariectomized female mice, whereas th

190 iota/lambda-antagonist disrupts late-LTP and spatial memory in PKMzeta-null mice but not in wild-type

191 General anesthesia has been shown to impair spatial memory in rats and this performance is dependent

192 d neurogenesis interferes with the recall of spatial memory in rats.

193 eptide load in the brain, alpha-MSH improves spatial memory in TgCRND8 mice and prevents alterations

194 e hippocampus hinders retention of long-term spatial memory in the Morris water maze.

195 textual fear conditioning test and long-term spatial memory in the Morris water maze.

196 the reduced expression prevents retention of spatial memory in the water maze.

197 Aged C57BL/6J control mice showed impaired spatial memory in the Y-maze; this improved with GR bloc

198 that have been implicated in landmark-driven spatial memory in walking flies and memory for visual pa

199 Moreover, LPS injection impaired spatial memory in WT mice, whereas interestingly, the Fa

200 at systemic pools of TIMP2 are necessary for spatial memory in young mice, while treatment of brain s

201 quisition of select types of associative and spatial memories increases the number of these cells tha

202 Interestingly, synaptic activity and spatial memory induces Crtc1 dephosphorylation (Ser151),

203 ransformation of a new hippocampal-dependent spatial memory into a remote one also depending on corti

204 approach has shown how the incorporation of spatial memory into animal movement models can improve e

205 Here, we incorporated spatial memory into step selection functions (SSF) to un

206 behavioral tests reveal that in PC7 KO mice spatial memory is intact and plasticity of responding is

207 eptiles, birds, and mammals, its function in spatial memory is said to be highly conserved.

208 ctivation did enhance object recognition and spatial memory, it did so by activating different cell-s

209 ce to impair radial maze performance despite spatial memory itself being normal.

210 us and CA1 subfields of the hippocampus form spatial memories just as well as wild-type mice, but the

211 er 5 days of testing, providing evidence for spatial memory lasting 24 hr.

212 w onto cognitive processing in tasks such as spatial memory, linguistic processing, and decision maki

213 s that rely on flexible navigation, impaired spatial memory may affect survival in the wild.

214 , supporting the theory that an externalized spatial memory may be the functional precursor to the in

215 ssment demonstrated impaired recognition and spatial memory, measured by novel object recognition and

216 (Rey Auditory-Verbal Learning Test), visual-spatial memory (Medical College of Georgia Complex Figur

217 Hippocampal NMDA receptors may influence spatial memory more subtly than previously thought.

218 lthough CFA, by itself, had little effect on spatial memory, morphine administered to pain-free anima

219 of cognitive function, including deficits in spatial memory, object recognition, and fear conditionin

220 henylethynyl)pyridine hydrochloride impaired spatial memory of old Pdyn(-/-) mice.

221 neurons in brain structures that instantiate spatial memory often exhibit firing fields that are stro

222 portance of land cover type, time of day and spatial memory on the animals' space use.

223 a deterioration in working memory and visual spatial memory over a period of up to 5 years.

224 ic topology, how such a network can maintain spatial memory over time.

225 This study describes a novel spatial memory paradigm for monkeys and reports the effe

226 mining the role of theta phase precession in spatial memory, particularly sequence retrieval, are als

227 restored phosphorylation of beta-CaMKII and spatial memory performance in APP/PS1 Ear2(-/-) mice.

228 activation after psychosocial stress impairs spatial memory performance independent of deficits in ne

229 Spatial memory performance was partly improved by treatm

230 EB signaling in the hippocampus and impaired spatial memory performance, while optoA2AR activation in

231 functional impairment in the form of reduced spatial memory performance.

232 rmore, DSP-8658-treated mice showed improved spatial memory performance.

233 y floors, and also crucially by columns - on spatial memory performances.

234 the gene avpr1a) in brain regions related to spatial memory predict male space use and sexual fidelit

235 Here we identified significant, enduring spatial memory problems in male rats following experimen

236 n individual theta cycles for more efficient spatial memory processing.

237 n of memory processes, selectively modulates spatial memory recall of stressful experiences.

238 ere that RSD caused transient impairments in spatial memory recall that resolved within 28 d.

239 These results indicate that spatial memory reconsolidation depends on the functional

240 beta + EB) groups failed to improve episodic spatial memory relative to oil-treated animals, indicati

241 hat interfere with one another to synthesize spatial memory representations.

242 ze tests, which measure short- and long-term spatial memory, respectively.

243 loss of Lphn2 from the CA1 region increased spatial memory retention but decreased learning of seque

244 ed to their sham controls without exhibiting spatial memory retention deficits.

245 Impairments in object recognition, spatial memory retention, and network stability followin

246 ys a key role in the selective regulation of spatial memory retrieval of stressful experience, sheddi

247 nduces major deficits in a strategy shifting/spatial memory retrieval task.

248 endent BDNF expression significantly impairs spatial memory reversal and contextual memory extinction

249 ted in tasks that do not require navigation, spatial memory seems unaffected by lesions of the hippoc

250 ffects of LCPUFAs were not found on tasks of spatial memory, simple inhibition, or advanced problem s

251 shifting structure), the hippocampus (as the spatial memory substrate), and the ventral midline thala

252 We provide a unique demonstration of a spatial memory system in a nonneuronal organism, support

253 on, participants performed a virtual reality spatial memory task analogous to the Morris water maze a

254 vity in rats trained to perform a "standard" spatial memory task in a plus maze and in two new task v

255 nisms, we trained rats to perform a standard spatial memory task in a plus maze and tested how traini

256 ted mice performed a classical goal-directed spatial memory task in a rectangular chamber.

257 al epilepsy patients performing a self-paced spatial memory task in a virtual environment.

258 f performance in a working memory task and a spatial memory task in rodents and nonhuman primates, re

259 inactivation impaired recall in a classical spatial memory task in the Morris water maze.

260 Despite learning a spatial memory task normally and displaying normal brain

261 Here we trained rats on a spatial memory task, and showed that subsequent sleep pe

262 In the spatial memory task, rats searched for a depleting food

263 Animals were tested on a self-ordered spatial memory task, the Hamilton Search Task.

264 Additional effects of HT-0712 were seen in a spatial memory task.

265 xercise enables strong discrimination in the spatial memory task.

266 campal region of rats while they performed a spatial memory task.

267 Both effects predict rat performance in a spatial memory task.

268 common approach that approaches nonspecific spatial memory tasks to evaluate cognition, but also wou

269 linically relevant given that the object and spatial memory tasks used in monkeys are often translate

270 In goal-directed spatial memory tasks, some place fields differentiate be

271 ficant improvements in performing short-term spatial memory tasks, which upon continued suppression t

272 red long-term depression and performances on spatial memory tasks.

273 tention but decreased learning of sequential spatial memory tasks.

274 However, a spatial memory test in the forms of the Morris water maz

275 well as dysfunctional hippocampus-dependent spatial memory tested in the object-placement and the Y-

276 n, novel object recognition, and Barnes maze spatial memory tests.

277 als produced profound detrimental effects on spatial memory that persisted longer than the analgesic

278 cement in long-term depression, and weakened spatial memory, these changes were not observed in oxyto

279 ovide the first evidence that tPA influences spatial memory through its preferential interaction with

280 control hippocampal synaptic plasticity and spatial memory through the hyperpolarization-activated c

281 ve evolved life-histories requiring reliable spatial memories to support the task of provisioning the

282 ells are engaged during the consolidation of spatial memories to the neocortex.

283 s, restored both postnatal proliferation and spatial memory to normal levels.

284 data suggests that vision, echolocation, and spatial memory together with the possible exercise of an

285 y in the hippocampus of APPSw,Ind mice after spatial memory training.

286 rmining excitatory neuronal architecture and spatial memory via their ability to regulate Arc/Arg3.1.

287 Rat hippocampus-dependent spatial memory was evaluated on postnatal days 49-60.

288 Spatial memory was examined 48 h after EB/oil treatment.

289 Spatial memory was impaired on the object recognition ta

290 Spatial memory was investigated on a radial arm maze.

291 lucocorticoid receptors (GRs)] are involved, spatial memory was measured in aged 11beta-HSD1(-/-) mic

292 After 1 month, spatial memory was tested in the Y maze with the novel a

293 sensory input from echolocation, vision, and spatial memory, we conducted an experiment in which bats

294 Despite decades of research on spatial memory, we know surprisingly little about how th

295 hippocampus is necessary for nonnavigational spatial memory, we selected a technique that avoids long

296 essing FKBP1b showed dramatic enhancement of spatial memory, which correlated with marked reduction o

297 ing a suite of sensory modalities that blend spatial memory with input from vision, tactile sensing,

298 engaging higher cognitive functions such as spatial memory, with significance for the "nature versus

299 drawn from self-administration and underwent spatial memory (Y-maze) and working memory (T-maze) test

300 .54 [1.67], p = 0.010, respectively), visual-spatial memory (z score = -1.65 [1.37], p = 0.008; z sco