ライフサイエンスコーパス: spatiotemporal

1 ulate and downregulate such forces with high spatiotemporal accuracy.

2 lize and quantify the production of ROS with spatiotemporal accuracy.

3 c in polycystic kidney disease; however, its spatiotemporal actions are unclear.

4 cally linked to enhanced RhoA but restricted spatiotemporal activation of Cdc42.

5 patterned by inductive cues that control the spatiotemporal activities of transcription factors.

6 hifting neurons exists in two subtypes, with spatiotemporal activity profiles that suggest different

7 ics towards a special regime with scale-free spatiotemporal activity, after an initial large-scale tr

8 ive adhesions are necessary to reproduce the spatiotemporal adhesion patterns.

9 e plasma membrane tension induce significant spatiotemporal alterations in endocytic clathrin coat dy

10 In this work, a spatiotemporal analysis of HMPV replication and transcri

11 To provide a detailed spatiotemporal analysis of kidney vascularisation, we co

12 l and temporal cortices, permitting detailed spatiotemporal analysis of word retrieval processes.

13 Spatiotemporal analysis revealed these asymmetrical BP n

14 We found that this spatiotemporal association of the fusion proteins select

15 We applied this new algorithm to construct a spatiotemporal atlas from MRI of 81 normal fetuses scann

16 Water is a fundamental resource, yet its spatiotemporal availability in East Africa is poorly und

17 Spatiotemporal balancing of cellular proliferation and d

18 cy further highlights the reliability of the spatiotemporal brain activation pattern as a measure of

19 These data reveal that the spatiotemporal cell expansion events driving this transi

20 Our purpose was to define the spatiotemporal changes in microglia morphology over 28 d

21 tex after laser nano-ablation, we assess the spatiotemporal changes of actomyosin-dependent force and

22 Here we characterize spatiotemporal changes of the elastic stiffness of the i

23 d of complex natural scenes from this set of spatiotemporal channels [6-14].

24 5, 16] that simultaneously activate multiple spatiotemporal channels.

25 Spatiotemporal characteristics of recombination events a

26 Next, we conducted a detailed spatiotemporal characterization of these cells before, d

27 omosome dynamics allows the investigation of spatiotemporal chromatin organization and its role in ge

28 vents carry the signature of scale-invariant spatiotemporal clusters, neuronal avalanches.

29 Here we show that spatiotemporal CNNs accurately categorize video stimuli

30 veals the key factors that underlie the high spatiotemporal complexity of their interactions.

31 Our kinetic results are consistent with spatiotemporal concepts where embedding the amide group

32 Three Bayesian spatiotemporal conditional autoregressive models were fi

33 In addition, the spatiotemporal configuration of forage resources that pr

34 Thus, it is important to understand the spatiotemporal consequences of the super-Mendelian popul

35 intuitive tools are needed to visualize the spatiotemporal context of expression data and help eluci

36 Progress on understanding spatiotemporal contextual processes in humans has been s

37 perinatal and neonatal stages, with precise spatiotemporal control but without surgical intervention

38 drug molecules from nanoscale carriers with spatiotemporal control is a key challenge in modern medi

39 Light-inducible systems allow spatiotemporal control of a variety of biological activi

40 id crystalline networks (LCNs) to facilitate spatiotemporal control of alignment, domain structure, a

41 esis of unicellular organisms depends on the spatiotemporal control of cell polarity.

42 n-to-colorless), leading to trackability and spatiotemporal control of CO release.

43 Thus, precise spatiotemporal control of developmental gene expression

44 eration in planarians is mediated by precise spatiotemporal control of gene expression and is crucial

45 rotein, i.e., CD2AP, to allow a balanced and spatiotemporal control of its adhesive function.

46 To study the spatiotemporal control of mitotic progression, we develo

47 We demonstrate the spatiotemporal control of oncogene expression in live ze

48 roadly, this approach introduces the precise spatiotemporal control of optogenetics to the molecular

49 We propose that polarity-induced spatiotemporal control of Rok and Pkn is important for u

50 Spatiotemporal control of the cAMP signaling pathway is

51 There is growing interest in designing spatiotemporal control over enzyme activities using noni

52 er bioorthogonal conditions enables accurate spatiotemporal control over protein or drug activity.

53 Spatiotemporal control over the release or activation of

54 iological and material systems with the high spatiotemporal control provided by pulsed laser irradiat

55 olding promise as light-activated agents for spatiotemporal controlled delivery of therapeutics.

56 Prefrontal-dependent deficits in the spatiotemporal coordination of NREM sleep oscillations t

57 ng data that exhibit both seasonal trend and spatiotemporal correlation, using an application to resp

58 rthogonal function analysis shows consistent spatiotemporal correspondence between OCO-2 SIF and GPP

59 r than initiating coarse-to-fine processing, spatiotemporal coupling in the early visual pathway buil

60 hin 100 m of each location when it was open (spatiotemporal coverage) for Toronto overall and downtow

61 ded for precise assessment of the underlying spatiotemporal CSD profiles.SIGNIFICANCE STATEMENT Despi

62 spread of gypsy moth has produced unrivalled spatiotemporal data across the invasion front.

63 Studying Eph activation kinetics requires spatiotemporal data on the number and distribution of re

64 These spatiotemporal differences enhanced the contrast between

65 us, distinct mechanisms operate in different spatiotemporal dimensions of J-RGC dendritic patterning

66 This spatiotemporal disordered flow radically changes nutrien

67 ring of intracardiac electrograms exhibiting spatiotemporal dispersion is indicative of AF drivers.

68 To establish the mechanism underlying spatiotemporal dispersion of AF electrograms, the author

69 The authors evaluated the usefulness of spatiotemporal dispersion, a visually recognizable elect

70 e tight control of its endogenous levels and spatiotemporal distribution a necessity.

71 ll brain regions simultaneously and that its spatiotemporal distribution is due to heterogeneous regi

72 The in vivo spatiotemporal distribution of Abeta in AD can be mathem

73 ed mechanical inference method to obtain the spatiotemporal distribution of cellular stresses from me

74 vely associated with high abundance and wide spatiotemporal distribution of cod eggs.

75 tal stages and environmental conditions, the spatiotemporal distribution of GA in vivo remains unclea

76 ologic studies collecting information of the spatiotemporal distribution of rotavirus VP7 (G) and VP4

77 ffect is limited by the uncertainties of its spatiotemporal distribution, especially over remote ocea

78 ason temperature shift, CTI shift, and their spatiotemporal divergence - the local climatic debt.

79 functions to each CRM, i.e. to determine the spatiotemporal domains or cell-types where it drives exp

80 and integration of network processes across spatiotemporal domains.

81 Our study supports an altered spatiotemporal dynamic of NMDAR-DeltaCa(2+) signalling i

82 Inducing this spatiotemporal dynamic using closed-loop optogenetic sti

83 ysis, Monte Carlo simulations and continuous spatiotemporal dynamical evolution from partial differen

84 network enables mechanistic analysis of its spatiotemporal dynamics and evolutionary diversification

85 Interestingly, large-scale spatiotemporal dynamics are revealed in HGA, but less ap

86 However, their spatiotemporal dynamics during behavior are poorly under

87 The reasons behind this complex spatiotemporal dynamics have yet to be clarified.

88 , and how topology can enrich the collective spatiotemporal dynamics in inherently non-equilibrium sy

89 lticomponent nature of these systems and the spatiotemporal dynamics involved as proteins interact an

90 s provide evidence that targeting endogenous spatiotemporal dynamics is a potential therapeutic appro

91 opy, we determined in vivo stoichiometry and spatiotemporal dynamics of a GFP tagged repressor, Mig1,

92 we present a mechanistic model in which the spatiotemporal dynamics of GapR are primarily driven by

93 we use a synthetic system to understand the spatiotemporal dynamics of growth and to study acquired

94 sights on the relative contributions and the spatiotemporal dynamics of GWET and BWET, which could le

95 Understanding the multi-scale, spatiotemporal dynamics of human seizures-and connecting

96 extensive stocking records, we evaluate the spatiotemporal dynamics of hybridization between native

97 Here we characterized the spatiotemporal dynamics of molecular activity levels in

98 We propose that the spatiotemporal dynamics of mRNAs can give rise to protei

99 Here, we examined the spatiotemporal dynamics of Mtb-containing phagosomes and

100 ing a beamforming approach to illuminate the spatiotemporal dynamics of neuronal activity.

101 arization microscopy approach to measure the spatiotemporal dynamics of order and disorder of the des

102 actor as a robust metric for quantifying the spatiotemporal dynamics of order and disorder.

103 To measure quantitatively the spatiotemporal dynamics of protein synthesis in growth c

104 igh-resolution live imaging, we examined the spatiotemporal dynamics of RNA and LPS in retinal axons

105 Thus, altered spatiotemporal dynamics of the NMDAR-DeltaCa(2+) respons

106 We examined the spatiotemporal dynamics of these complementary processes

107 Here, we test for the first time the spatiotemporal dynamics of these processes by collecting

108 emergence of periodic changes in length and spatiotemporal dynamics of traction forces measured in c

109 The spatiotemporal dynamics of vacuolar EhRab35 and its exch

110 ical systems analysis to measure whole-brain spatiotemporal dynamics while subjects make decisions re

111 Engineered tumor models recapitulating these spatiotemporal dynamics will permit assessing the functi

112 core molecular circuitry, circuit design and spatiotemporal dynamics.

113 In this study, we report that spatiotemporal enrichment of actin monomers (G-actin) in

114 ch appropriately captures and integrates the spatiotemporal events occurring at the cellular level in

115 We imaged the subsequent spatiotemporal evolution in fluorescence intensity and o

116 hips, structure, gene flow barriers, and the spatiotemporal evolution of populations.

117 -diffraction resolution, thus characterizing spatiotemporal exciton migration on its native nanometre

118 mya), suggesting that the differentiation in spatiotemporal expression between the duplicated genes i

119 To experimentally address the spatiotemporal expression information associated with th

120 anization that was induced by changes in the spatiotemporal expression of actin binding/regulatory pr

121 tion of MT polymerization via changes in the spatiotemporal expression of EB1 (end-binding protein 1)

122 tudy, immunohistochemical analysis reveals a spatiotemporal expression of GPR64 in the uterus during

123 ments and noncoding RNAs in controlling this spatiotemporal expression of Hox genes, but disentanglin

124 del can accurately recapitulate the observed spatiotemporal expression of the pair-rule genes, but on

125 We compared the spatiotemporal expression patterns of CorTFL1, CorAP1 an

126 Analysis of spatiotemporal expression showed that Irf6 and Twist1 ar

127 networks exhibited distinct and recognizable spatiotemporal-expression patterns in human brains and l

128 ious studies did not control for confounding spatiotemporal factors or investigate the relationship b

129 ures and MVD, and also demonstrated that the spatiotemporal features extracted from DCE-MRI provided

130 Thus, although many spatiotemporal features of neural population activity, o

131 at this coarse-to-fine sequence results from spatiotemporal filtering by neurons in the early visual

132 fringes that are analyzed using an efficient spatiotemporal filtering method, which allows us to asse

133 pes, create structural maps, and resolve the spatiotemporal flow dynamics.

134 This approach provides a quantitative spatiotemporal follow-up of disease course in relation t

135 al-like breast cancer, where Ror2 provides a spatiotemporal function to regulate the balance of Wnt s

136 s suggest that the regulatory foundation for spatiotemporal gene expression evolved prior to the dive

137 HSS shows highly diverse spatiotemporal gene expression in various PA-producing s

138 d transcription factor binding in regulating spatiotemporal gene expression is essential for embryoge

139 ge determination, morphogenesis, and dynamic spatiotemporal gene expression patterns.

140 s a fundamental regulatory mechanism driving spatiotemporal gene expression programs during animal de

141 Systematic analyses of spatiotemporal gene expression trajectories during organ

142 Precise spatiotemporal gene regulation is paramount for the esta

143 ed an image-guided genomics technique termed spatiotemporal genomic and cellular analysis (SaGA) that

144 rical activity in primary L-cells to include spatiotemporal glucose and Ca(2+) dynamics, and GLP-1 se

145 isotropic culture fails to recapitulate the spatiotemporal gradients present during native developme

146 Spatiotemporal heterogeneities of eco-exergy and specifi

147 ng due to their architectural complexity and spatiotemporal heterogeneity.

148 indicating that IL1B2 may be involved in the spatiotemporal increase in conceptus estrogen synthesis

149 n rates from two Colorado basins to create a spatiotemporal industrial activity model to develop an i

150 stage of the cerebellar cortex and processes spatiotemporal information transmitted by mossy fiber in

151 The importance of this spatiotemporal interaction between these distinct feedba

152 spatial differentiation of fibroblasts, ii) spatiotemporal interactions between breast cancer cells

153 optical control of kinases would enable fine spatiotemporal interrogation or manipulation of these va

154 novel R26-LSL-JAG1 mouse model that enables spatiotemporal Jagged1 expression.

155 More importantly, NIR-controlled spatiotemporal knockdown of GFP expression is successful

156 lines, consistent results were observed with spatiotemporal knockdown of miR-8 and luciferase assays.

157 This strategy thus greatly expands the spatiotemporal length scales of live-cell single-molecul

158 ontextual manner, more information about the spatiotemporal localization, deposition, and function of

159 mechanical actuators and allows quantitative spatiotemporal measurements of mechanical properties in

160 ture, Herault et al. (2017) uncover a unique spatiotemporal mechanism of granulocyte-macrophage proge

161 We used complementary time series and spatiotemporal methods (synthetic controls and hierarchi

162 from each other and from priorities based on spatiotemporal metrics such as climatic velocity.

163 ypothesis that different Mn entry routes and spatiotemporal Mn distributions can reflect different me

164 before the onset of PD was estimated using a spatiotemporal model by linking each participant's place

165 We developed a multiscale spatiotemporal model for the interaction of a T cell and

166 based distance to a major roadway and used a spatiotemporal model to estimate the annual mean concent

167 cted at each participant's residence using a spatiotemporal model.

168 s; daily PM2.5 estimates were obtained using spatiotemporal models.

169 Recent research has explored the spatiotemporal modulation of permittivity to break Loren

170 s that are highly active ('hot') in specific spatiotemporal niches, and the evolutionary selection of

171 provides an overview of arguments as to how spatiotemporal nutritional fluxes influence the successi

172 and municipal locations were then ranked by spatiotemporal OHCA coverage.

173 sitizing proteins, such as KillerRed, permit spatiotemporal optogenetic ablation with low-power laser

174 in achieving a robust T-cell response is the spatiotemporal orchestration of antigen cross-presentati

175 unidirectional differentiation in a precise spatiotemporal order.

176 We investigated the spatiotemporal organization of SPN ensemble activity in

177 However, little is known about the spatiotemporal organization of this activity.

178 ntra- and interday fine-scale variability of spatiotemporal oxygen dynamics under varying hydrologica

179 g a naturalistic route-learning paradigm and spatiotemporal pattern analysis of human fMRI data, we f

180 Each variant showed a distinct spatiotemporal pattern of altered functional connectivit

181 ent, as well as the precise moment-to-moment spatiotemporal pattern of fixations during viewing of co

182 The results indicate either a dynamic spatiotemporal pattern whereby low and high POMC synthes

183 The expression data revealed a complex spatiotemporal patterning of events starting with neural

184 ctive control of specific targets depends on spatiotemporal patterning of the calcium signal and deco

185 eous activity are organized into stereotyped spatiotemporal patterns across the entire brain.

186 Here we report dynamic spatiotemporal patterns and new regulators of RNA editin

187 We further find that spatiotemporal patterns differ between licking and bruxi

188 nsic neural coupling, which reveals specific spatiotemporal patterns in the form of resting state net

189 ior and mental states must be implemented by spatiotemporal patterns of activity across neuronal popu

190 h reproductive success, which, combined with spatiotemporal patterns of bill length, suggested ongoin

191 Therefore, distinct spatiotemporal patterns of brain activity were observed

192 n sleep cycle is characterised by changes in spatiotemporal patterns of brain activity.

193 t temperature has a significant influence on spatiotemporal patterns of branching coral growth, and h

194 ysis also provides two key insights into the spatiotemporal patterns of drought recovery time: first,

195 However, the mechanisms by which spatiotemporal patterns of gene expression modify cellul

196 d, we used magnetoencephalography to measure spatiotemporal patterns of neural activity with high tem

197 The unique spatiotemporal patterns of neuronal synchrony signify di

198 orting these predictions, the generation and spatiotemporal patterns of propagation were most variabl

199 ion of interest-based analyses comparing the spatiotemporal patterns of variant-specific regions of i

200 one of the most important processes shaping spatiotemporal patterns of variation in genetic, morphol

201 receptor (GPCR) signaling occurs in complex spatiotemporal patterns that are difficult to probe usin

202 In cortex, these transients form widespread spatiotemporal patterns with largely unknown statistical

203 les in response to inputs approximating real spatiotemporal patterns, we constructed a large-scale 3D

204 tivities of these proteins have a variety of spatiotemporal patterns, which orchestrate signaling act

205 timing of 22 plant species based on >200 000 spatiotemporal phenological observations from across the

206 ological functions, due to the high level of spatiotemporal precision achievable with light.

207 ogenetic system for activating Erk with high spatiotemporal precision in vivo.

208 rlying complex mammalian behaviors with high spatiotemporal precision.

209 gene activity via epigenetic modulation with spatiotemporal precision.

210 ammalian tissue development is an intricate, spatiotemporal process of self-organization that emerges

211 o create ultrashort pulses with a variety of spatiotemporal profiles.

212 A new spatiotemporal projection (STP) technique that is free o

213 These findings have revealed fundamental spatiotemporal properties of individual release sites in

214 Furthermore, the spatiotemporal properties of the release sites were acti

215 Moreover, how neural activity regulates the spatiotemporal properties of the release sites within in

216 plex brain disorders are distributed through spatiotemporal protein complexes.

217 The small G protein Arf1 regulates the spatiotemporal recruitment of AP-1 and also drives a con

218 ing in parallel imaging readout, followed by spatiotemporal registration and entropy-based retrospect

219 er, the molecular mechanisms determining its spatiotemporal regulation are largely unknown.

220 Spatiotemporal regulation during induction in vitro reca

221 o from self-assembling hMSCs by implementing spatiotemporal regulation during induction.

222 c maturation and synaptic formation and that spatiotemporal regulation of CARM1 activity modulates ne

223 cess to DNA-binding proteins for the correct spatiotemporal regulation of gene expression.

224 nt and independent branches enables distinct spatiotemporal regulation of germ cell migration.

225 Here, we provide evidence for spatiotemporal regulation of glycolysis in the posterior

226 To parse out the spatiotemporal regulation of islet cell differentiation,

227 review covers recent findings concerning the spatiotemporal regulation of motility and cell division

228 Using immunohistochemistry, we observed spatiotemporal regulation of Nogo-A and NgR in cell bodi

229 To determine the spatiotemporal relationships among intrinsic networks of

230 he anterior hypothalamus and may mediate the spatiotemporal release of neuropeptides and their intera

231 r mechanisms by which c-Myb achieved precise spatiotemporal repression of Rag expression remained obs

232 es from mice by taking advantage of the high spatiotemporal resolution afforded by genetically encode

233 re we describe a technique that improves the spatiotemporal resolution and collection efficiency of L

234 afish, offers a powerful combination of high spatiotemporal resolution and higher vertebrate relevanc

235 gradients in vitro is challenging due to low spatiotemporal resolution and poor longevity of gradient

236 development of ten C. elegans larvae at high spatiotemporal resolution from hatching to adulthood ( a

237 electron diffraction (UED) with atomic-scale spatiotemporal resolution has been employed to study the

238 We used assays with spatiotemporal resolution in Drosophila melanogaster (fr

239 lity to dissect infection dynamics at a high spatiotemporal resolution makes this zebrafish model a u

240 Here, we use high spatiotemporal resolution neuromagnetic recordings to ex

241 0-nm-wide shaft of live primary cilia with a spatiotemporal resolution of 2 ms and <16 nm.

242 se in unrestrained animals has combined high spatiotemporal resolution with large volume coverage.

243 e activation of PLCs in live cells with high spatiotemporal resolution.

244 of axonal morphology and activity with high spatiotemporal resolution.

245 cellular structures and organelles with high spatiotemporal resolution.

246 ies and acquires viscoelastic data with high spatiotemporal resolution.

247 eins may be coordinately regulated with high spatiotemporal resolution.

248 mage micrometastases in multiple organs with spatiotemporal resolution.

249 elivery of small signaling compounds at high spatiotemporal resolution.

250 sses with light, which can be delivered with spatiotemporal resolution.

251 toring of the near surface often has limited spatiotemporal resolutions because dense seismic arrays

252 -time PDGFR activity in live cells with high spatiotemporal resolutions.

253 experimental approach can determine the full spatiotemporal response of an electron system.

254 h the goal of visualizing, in real-time, the spatiotemporal response of the cell milieu to electrophi

255 Our results indicate that the spatiotemporal restriction of BR biosynthesis at boundar

256 topological structures that undergo precise spatiotemporal restructuring during healthy development.

257 In this study, we examined the spatiotemporal role of Bim in the thymic selection of CD

258 dicates that understanding the diversity and spatiotemporal role of the inflammatory response and its

259 ensional process with expressions varying by spatiotemporal scale.

260 covariates and decomposition of PM2.5 into 2 spatiotemporal scales.

261 nce in evolutionary dynamics across multiple spatiotemporal scales.

262 iological and ecological interactions across spatiotemporal scales.

263 on and access to meaning in combination with spatiotemporal searchlight representational similarity a

264 ling us to link the informational content of spatiotemporal sensory dynamics to behavior.

265 ate both cluster populations and we observed spatiotemporal separation between immune and growth sign

266 lism and lipid utilization are linked to the spatiotemporal sequence of tissue rehydration.

267 lived mutants regulate autophagy in distinct spatiotemporal-specific manners to extend lifespan.

268 ependent change in GCL localization provides spatiotemporal specificity for RTK degradation and seque

269 le in this process, suggesting potential for spatiotemporal stability of the coastal hybrid form and

270 icrogravity, and we describe novel predicted spatiotemporal states that merit further study.

271 rvating the glabrous skin of the hand to any spatiotemporal stimulus applied to the skin.

272 ation analyses, we identified the particular spatiotemporal stimulus patterns that elicit a stream or

273 but have yielded few insights into the local spatiotemporal structure of endemic transmission.

274 The spatiotemporal structure of the sensory input provides i

275 ndings represent a mechanism for controlling spatiotemporal synaptic integration in SPNs.

276 zing and scaling up snail control, including spatiotemporal targeting, environmental diagnostics, bet

277 ng these data sets to identify and track the spatiotemporal trajectories of genetic variants associat

278 l and systems neuroscience is to relate this spatiotemporal trajectory of maturation to circuit-level

279 oreceptor genes because each gene's distinct spatiotemporal transcription patterns are determined by

280 tification is critical for understanding the spatiotemporal transcriptional regulation during develop

281 tion, we performed RNA sequencing over these spatiotemporal transitions in the AGM region and support

282 y, CBD-tau- and PSP-tau-injected mice showed spatiotemporal transmission of glial tau pathology, sugg

283 ns with different time kinetics and regulate spatiotemporal tumour plasticity.

284 ecology and catchment hydrology to quantify spatiotemporal variability across scales, which we teste

285 ork has shown that balanced networks amplify spatiotemporal variability and account for observed asyn

286 he large dimensionality of the problem (e.g. spatiotemporal variability in flood magnitude and the re

287 ensities-i.e., an Allee effect-combined with spatiotemporal variability in population density behind

288 ace temperature (SST) records to reconstruct spatiotemporal variability in regional and global SSTs d

289 4 in the Eagle Ford basin, Texas, to examine spatiotemporal variability of methane emissions using fo

290 uence of drought and insect outbreaks showed spatiotemporal variability.

291 These include assessment of spatiotemporal variation in fine-root traits, integratio

292 Spatiotemporal variation in immunization performance and

293 assessing risk effects is characterizing the spatiotemporal variation in predation risk.

294 s of the cellular microenvironment and their spatiotemporal variations are thought to play a central

295 However, the extent to which SIF tracks spatiotemporal variations in GPP remains unresolved.

296 We also illustrate spatiotemporal variations of MEFs and explore implicatio

297 Spatiotemporal variations of neurogenesis are thought to

298 ning strategies or analyze cells in a global spatiotemporal video context performed better than other

299 ombinant proteins is developed to allow high spatiotemporal visualization and analysis of gene and pr

300 rate that plateau potentials can broaden the spatiotemporal window for integrating excitatory inputs