ライフサイエンスコーパス: specific autoantibody

1 provided new information about many of these specific autoantibodies.

2 dromes of which many are closely linked with specific autoantibodies.

3 ausally related to the deposition of antigen-specific autoantibodies.

4 creened to identify peptides targeted by MGO-specific autoantibodies.

5 of microarrays was used to identify disease-specific autoantibodies.

6 sting of T1D subjects with and without organ-specific autoantibodies.

7 therothrombotic status, further modulated by specific autoantibodies.

8 solid supports for the selective capture of specific autoantibodies.

9 tion recognized by rheumatoid arthritis (RA)-specific autoantibodies.

10 d spinal cords of MHV-infected mice with CNS-specific autoantibodies.

11 titer of anti-RNA binding protein (anti-RBP)-specific autoantibodies.

12 CVD in APS and SLE; 2) assess the effects of specific autoantibodies.

13 y as demonstrated by the presence of disease-specific autoantibodies.

14 to isolate several dozen unique IgG platelet-specific autoantibodies.

15 haracterized by a variety of circulating SSc-specific autoantibodies.

16 produced lower levels of mouse thyroglobulin-specific autoantibodies after immunization with MTg and

17 patients with chronic prostatitis possessed specific autoantibodies against the human SVS2-like semi

18 Recently, we identified a new SSc-specific autoantibody against portions of fibrillin-1, a

19 re, and have provided evidence that myositis-specific autoantibodies and autoreactive T cells are pre

20 Specific autoantibodies and class II HLA genotypes were

21 e SSc families tend to be concordant for SSc-specific autoantibodies and HLA haplotypes; familial SSc

22 O mice is preceded by the development of OVA-specific autoantibodies and is delayed in B cell-deficie

23 lude recent findings related to the myositis-specific autoantibodies and magnetic resonance imaging o

24 ter criteria is proposed to include myositis-specific autoantibodies and magnetic resonance imaging.

25 n of increased expression of ISGs with lupus-specific autoantibodies and nephritis in humans.

26 treated with anti-CD20 Ab at a time when PG-specific autoantibodies and T cell activation were evide

27 ether IFNalpha induction was associated with specific autoantibodies and/or clinical features of the

28 dependent Ab production, have reduced GM-CSF-specific autoantibody and do not develop PAP.

29 plement-dependent pathogenic role of dry-eye-specific autoantibodies, and suggest autoantibody deposi

30 atched for both genetic ancestry and disease-specific autoantibodies (anti-citrullinated protein anti

31 y index, a history of nephritis, and disease-specific autoantibodies (anti-dsDNA, anti-Smith (Sm), an

32 TMPD did not induce lupus-specific autoantibodies (anti-RNP, anti-Sm, anti-double-

33 Anti-GP2 IgG and IgA, constituting novel CD specific autoantibodies, appear to be associated with di

34 ve been recently associated with the disease-specific autoantibody aquaporin-4, thought to be pathoge

35 cells and the occurrence of certain myositis-specific autoantibodies are striking features.

36 port a role for a complement activating AQP4-specific autoantibody as the initiator of the NMO lesion

37 anding of immunopathogenesis, histology, and specific autoantibody associations has broadened our und

38 subjects, including the presence of pancreas-specific autoantibodies, autoreactive CD4+ and CD8+ T ce

39 e course, with a progressive accumulation of specific autoantibodies before the onset of SLE, while p

40 e, myelin oligodendrocyte glycoprotein (MOG)-specific autoantibodies can initiate disease bouts by co

41 ta demonstrate that a precursor of a disease-specific autoantibody can be present in the preimmune re

42 oma, or both for clinical features and organ-specific autoantibodies characteristic of APS-I patients

43 We hypothesized that the presence of antigen-specific autoantibodies could be used as a "surrogate ma

44 Myositis-specific autoantibodies define clinical phenotypes in JI

45 ce produce high level of serum TNF-alpha and specific autoantibodies deposited onto brain blood vesse

46 en accompanied by the development of disease-specific autoantibodies directed against the SNF2-superf

47 Our data show how beta1AR-specific autoantibodies elicit DCM by agonistically indu

48 SLE-specific autoantibodies emerged in a sequential manner t

49 Less specific autoantibodies for systemic sclerosis and limit

50 he families of SLE probands, suggesting that specific autoantibody formation is partly genetically de

51 Anti-Sm is a common and specific autoantibody found in systemic lupus erythemato

52 t to other inflammatory myopathies, myositis-specific autoantibodies had not been found in sIBM patie

53 specific and sensitive determination of p53-specific autoantibodies has been developed for the first

54 In dogs with inflammatory myopathy, muscle-specific autoantibodies have been found, especially in m

55 nd tested for association with seven disease-specific autoantibodies in a large cross-sectional cohor

56 Organ-specific autoantibodies in motor unit disorders with wea

57 ical activity of SP077 in the recognition of specific autoantibodies in multiple sclerosis patients'

58 Aquaporin 4 (AQP4)-specific autoantibodies in neuromyelitis optica (NMO) ar

59 unlipoylated peptides are able to recognize specific autoantibodies in patients sera.

60 cs-based approach, we identified neurofascin-specific autoantibodies in patients with MS.

61 h unique specificities may represent disease-specific autoantibodies in patients with RA.

62 once disease was evident, we detected heart specific autoantibodies in PD-L1(-/-);MRL-Fas(lpr) mice.

63 inated peptides are major targets of disease-specific autoantibodies in rheumatoid arthritis.

64 Dramatic reductions in 23 myelin-specific autoantibodies in the 0.5 mg BHT-3009 arm were

65 self tolerance, including the deposition of specific autoantibodies in the respective target organs,

66 is extremely sensitive in detecting disease-specific autoantibodies in the sera of bullous pemphigoi

67 AMAs represents the most highly directed and specific autoantibody in autoimmune diseases.

68 In PF, desmoglein-1-specific autoantibodies induce blistering.

69 The concentration of PG-specific autoantibody is similar in mice sufficient or d

70 Here we show that TrkA-, TrkB-, and TrkC-specific autoantibodies isolated from the sera of four i

71 We hypothesized that specific autoantibodies may associate with IPF manifesta

72 Defining additional phenotype-specific autoantibodies may identify such circumstances.

73 we define a causal mechanism whereby beta1AR-specific autoantibodies mediate noninflammatory cardiomy

74 mphigus vulgaris (PV) is a prototypic tissue-specific autoantibody-mediated disease, in which anti-de

75 1, detected by DNA oligotyping) and myositis-specific autoantibodies (MSA) were determined in 224 pat

76 ong correlations between particular myositis-specific autoantibodies (MSAs) and clinical subsets.

77 Myositis-specific autoantibodies (MSAs) are directed against cell

78 IFNalpha production is induced by specific autoantibody-nuclear antigen immune complexes,

79 differences in the proportion of DM- and DM-specific autoantibodies observed around the world are no

80 Myositis-specific autoantibodies or myositis-associated autoantib

81 autoantibodies, revealed the presence of MOG-specific autoantibodies over vesiculated myelin networks

82 e factor in Korean patients without myositis-specific autoantibodies (Pcorr = 0.004, OR 0.046).

83 he treatment of juvenile DM in both myositis-specific autoantibody-positive and -negative patients.

84 , and TrkC, but not T. cruzi, are targets of specific autoantibodies present in the sera of patients

85 attenuate, but did not completely abolish HA-specific autoantibody production in an adoptive transfer

86 llular responses, and with elevated collagen-specific autoantibody production.

87 to PGIA is not due to the suppression of PG-specific autoantibody production.

88 s also limits the potential to identify a CV-specific autoantibody profile.

89 se symptoms and clinical course, scleroderma-specific autoantibody profiles associate strongly with d

90 ations but are more strongly correlated with specific autoantibody profiles.

91 The identification of myositis-specific autoantibodies provides both diagnostic and pro

92 from a multiple sclerosis patient and by MBP-specific autoantibodies purified from multiple sclerosis

93 phy that these glucose-6-phosphate isomerase-specific autoantibodies rapidly localize to distal joint

94 lular staining patterns were determined, and specific autoantibody reactivities were assessed by immu

95 The discovery of increased specific autoantibody reactivity in MDS patients, provid

96 study reveals features of a disease- and Ag-specific autoantibody repertoire with preferred VH:VL us

97 rol sera by ELISA, we found a consistent and specific autoantibody response against Dsg1 and other ke

98 The association of a specific autoantibody response with distinct disease phe

99 IgG are not detectable within the strong Tg-specific autoantibody response.

100 B cell depletion reduced the PG-specific autoantibody response.

101 logy was used to study islet and other organ-specific autoantibody responses in parallel.

102 Patients without myositis-specific autoantibodies showed a significant peak in sum

103 Sjogren's syndrome-specific autoantibodies (SSA/Ro and SSB/La) were detecte

104 l autoimmunity is presented in which epitope-specific autoantibody stimulates de novo autoimmune path

105 Myositis-specific autoantibodies target intracellular proteins in

106 Here, we investigated the feasibility of specific autoantibody targeting in pemphigus.

107 Specific autoantibody testing can help identify these pa

108 ic thrombocytopenic purpura caused by a GPVI-specific autoantibody that mediates clearance of the GPV

109 eth cells and were seropositive for defensin-specific autoantibodies; the presence of autoantibodies

110 highlights the recent work on novel myositis-specific autoantibodies, their autoantigen targets, the

111 n pregnant dams harbored DNA-specific, NMDAR-specific autoantibodies throughout gestation.

112 is the presence of high-titer and extremely specific autoantibodies to the E2 component of the pyruv

113 in-4 (AQP4) antibody (AQP4-antibody), an NMO-specific autoantibody to AQP4, the dominant water channe

114 been described recently in which an epitope-specific autoantibody to murine zona pellucida 3 induces

115 adic IIM, although the frequency of myositis-specific autoantibodies was lower in familial than in sp

116 patterns were seen in 6.1%; the most common specific autoantibodies were anti-Ro (3.9%) and anti-Su

117 MOG-specific autoantibodies were identified in a subset of A

118 Furthermore, HA-specific autoantibodies were induced in the absence of v

119 with active SLE, although the association of specific autoantibodies with chemokine score, a combined

120 l studies have implicated the association of specific autoantibodies with morphea subtype or severity

121 tures, such as autoimmune manifestations and specific autoantibodies, with patients affected by autoi