ライフサイエンスコーパス: specific immune response

1 s to that found following an influenza-virus-specific immune response.

2 the improved efficacy was a result of a Trp2-specific immune response.

3 encoding ovalbumin (MVA-OVA) on the allergen-specific immune response.

4 has been seen as a by-product of the myelin-specific immune response.

5 ated the role of IL-10 in modulating the RSV-specific immune response.

6 of an rNDV vector to induce a potent antigen-specific immune response.

7 by using TLR synergy to enhance the parasite-specific immune response.

8 ing APC recruitment, activation, and antigen-specific immune response.

9 n target organs after the development of the specific immune response.

10 a beneficial host proinflammatory and/or Ag-specific immune response.

11 ion by this vector induces a durable HIV Gag-specific immune response.

12 were 4-fold more likely to acquire a peptide-specific immune response.

13 in C57BL/6) was used to evaluate the antigen-specific immune response.

14 distant tumours by inducing a strong tumour-specific immune response.

15 , which was sufficient to trigger an antigen-specific immune response.

16 the activation of a clinically relevant AML-specific immune response.

17 col chitosan produced the most effective flu-specific immune response.

18 checkpoint of agonist quality necessary for specific immune response.

19 hanges that suggest modulation of the peanut-specific immune response.

20 e of gammadelta T cells in the mycobacterial-specific immune response.

21 al symptoms of the disease and mounted virus-specific immune responses.

22 ften associated with rapid viral escape from specific immune responses.

23 seq technology we identify genes involved in specific immune responses.

24 activation and with absent to minimal HIV-1-specific immune responses.

25 urs independently of T-cell-mediated antigen-specific immune responses.

26 e survival overall survival, and rate of CEA-specific immune responses.

27 ction as immunological adjuvants for antigen-specific immune responses.

28 ed toxins can be administered to mount toxin-specific immune responses.

29 ection in the context of quantifying antigen-specific immune responses.

30 n AMA1 were the targets of protective allele-specific immune responses.

31 tive jawless vertebrates capable of mounting specific immune responses.

32 t it contributes to the induction of antigen-specific immune responses.

33 bioactive cytokines and to initiate pathogen-specific immune responses.

34 ed on the evidence that Tregs suppress virus-specific immune responses.

35 eptional plasticity that characterizes virus-specific immune responses.

36 portant antigens that induce T cell-mediated specific immune responses.

37 ll proliferation, and attenuation of antigen-specific immune responses.

38 nsors are required for induction of pathogen-specific immune responses.

39 ation of adaptive serum and local chlamydial specific immune responses.

40 that can trigger inflammation and induce Ag-specific immune responses.

41 r (GM-CSF) induces follicular lymphoma (FL) -specific immune responses.

42 osuppressive neutrophils and restoring tumor-specific immune responses.

43 ier results in strong and effective pathogen-specific immune responses.

44 itutes an ideal model disease to study tumor-specific immune responses.

45 eclude the development of tumor- and patient-specific immune responses.

46 odies that can stimulate host tumour-antigen-specific immune responses.

47 including human immunodeficiency virus (HIV)-specific immune responses.

48 unique ability to characterize de novo HIV-1-specific immune responses.

49 n and a thorough understanding of early xeno-specific immune responses.

50 ice, and then mice were examined for antigen-specific immune responses.

51 alteration of the cytokine profile and virus-specific immune responses.

52 persists despite eliciting substantial virus-specific immune responses.

53 he presence of TLF promoted Th1-polarized Ag-specific immune responses.

54 conventional dendritic cells can enhance Ag-specific immune responses.

55 ial utility of DNA vaccines in generating Ag-specific immune responses.

56 hat sense danger signals and in turn trigger specific immune responses.

57 rived heat shock proteins can generate tumor-specific immune responses.

58 studies involving subjects with active HSV-2-specific immune responses.

59 e system and evaluated the resulting antigen-specific immune responses.

60 ated with T-cell activation but not with CMV-specific immune responses.

61 y, despite eliciting strong and stable virus-specific immune responses.

62 al products to subvert production of antigen-specific immune responses.

63 chinery necessary to activate potent antigen-specific immune responses.

64 CD279), resulting in dis-inhibition of tumor-specific immune responses.

65 pedition (CHE), as activators of ICS1 during specific immune responses.

66 mphoma cells and its ability to induce tumor-specific immune responses, 11 has the potential to be us

67 Regarding CD8(+) T cell-mediated Ag-specific immune responses, a heterogeneous pattern of re

68 he vaccinated patients, the development of a specific immune response after vaccination was associate

69 We have elicited local genital antigen-specific immune responses after topical application of a

70 PDT can induce a potent antigen- and epitope-specific immune response against a naturally occurring m

71 en challenges, mainly in the form of a human-specific immune response against the vector that poses a

72 se mice become infected with HCV, generate a specific immune response against the virus, and develop

73 e infection we observe what is potentially a specific immune response against the virus; a non-synony

74 ization with OMVs loaded with PhoA induced a specific immune response against this heterologous antig

75 ngs suggest that dysregulation of macrophage-specific immune responses against an otherwise harmless

76 d evaluate their abilities to induce antigen-specific immune responses against CHIKV.

77 Specific immune responses against EBV-infected B cells w

78 efficiently generate integrated and broad Ag-specific immune responses against NY-ESO-1 in cancer pat

79 xpressing the relevant VEGFR-2 CARs mediated specific immune responses against VEGFR-2 protein as wel

80 rate, the strength and efficiency of the non-specific immune response and characteristics affecting t

81 8(+) T cells is a hallmark of an adaptive Ag-specific immune response and constitutes a critical comp

82 that malignancy may initiate the scleroderma-specific immune response and drive disease in a subset o

83 nt in necrotic cells can sometimes provoke a specific immune response and it has been argued that nec

84 egress that allows the development of a CNS-specific immune response and the classical pathological

85 nderlying the modulation of both the malaria-specific immune response and the course of clinical mala

86 mors regardless of the potent systemic tumor-specific immune response and the increases of tumor infi

87 tinued regulation of the low-frequency graft-specific immune response and thus in maintenance of graf

88 y of these vaccines to induce functional HCV-specific immune responses and determine T-cell cross-rea

89 Strong Ag-specific immune responses and homeostatic expansion of h

90 How these isolates drive specific immune responses and how this affects fungally

91 onses evoked by helminths may modify malaria-specific immune responses and increase the risk of malar

92 t this combination significantly enhances Ag-specific immune responses and leads to complete eradicat

93 HIV-1-specific immune responses and longitudinal CD4(+) T cell

94 l unit was further characterized by helminth-specific immune responses and microarray analyses.

95 nnate and human immunodeficiency virus (HIV)-specific immune responses and of the generalized inflamm

96 mokines are critical for establishing tissue-specific immune responses and play key roles in modulati

97 location, and the capacity to elicit antigen-specific immune responses and protection against challen

98 iFT immune complexes, enhances F. tularensis-specific immune responses and protection against F. tula

99 summarise the current understanding of liver-specific immune responses and provide an outlook on futu

100 d LLO(91-99)/CD8(+)- and LLO(189-201)/CD4(+)-specific immune responses and recruited mature dendritic

101 nti-idiotype antibody to monitor a patient's specific immune responses and suggest routes for the imp

102 anticancer vaccines to enhance tumor antigen-specific immune responses and the need to explore dose a

103 f magnetically labeled APCs inducing a tumor-specific immune response, and that these cells can be ma

104 s linked with IgG2c isotype switching, virus-specific immune responses, and humoral autoimmunity.

105 ion, <2 copies/mL), T-cell activation, HIV-1-specific immune responses, and the persistence of cells

106 ysaccharide, they nevertheless initiate TLR4-specific immune responses, and these responses are impor

107 animals are able to develop efficient virus-specific immune responses, and thus can be employed for

108 ges for immunotherapy, measurement of tumour-specific immune responses, and understanding the associa

109 VIN elicited a statistically significant VZV-specific immune response approximately 28 days post-dose

110 d and elicited statistically significant VZV-specific immune responses approximately 28 days post-dos

111 Organ- and cell-specific immune responses are associated with the outcom

112 l IL-10 production and regulation of antigen-specific immune responses are controlled in vivo without

113 not all human immunodeficiency virus (HIV)-1-specific immune responses are equally effective at contr

114 Antigen-specific immune responses are impaired after allogeneic

115 immunological factors that initiate the lung-specific immune responses are unclear.

116 We propose sequence coverage by HIV Gag-specific immune responses as a possible correlate of pro

117 Secondary endpoints were chikungunya virus-specific immune responses assessed by ELISA and neutrali

118 ystemic reaction that includes an acute, non-specific, immune response associated, paradoxically, wit

119 lished EAMG, and that the MDSCs inhibit AChR-specific immune responses at least partially in an Ag-sp

120 its and risks of inducing high levels of SIV-specific immune responses at mucosal sites prior to SIV

121 First, specific immune responses become exhausted if they are s

122 uding the magnitude and quality of influenza-specific immune responses before vaccination.

123 Prior to a detectable virus-specific immune response (before day 5), the estimated h

124 demonstrated better cellular uptake and OVA-specific immune response both in vitro and in vivo.

125 atory T cell function and suppressed antigen-specific immune responses both in vitro and in vivo, inc

126 es not only need to induce a robust tumor Ag-specific immune response but also need to overcome the t

127 human immunodeficiency virus type 1 (HIV-1)-specific immune responses but cannot control immune acti

128 characteristic modifications in the allergen-specific immune response, but a detailed synthesis of OI

129 helminths can not only downregulate parasite-specific immune responses, but also modulate autoimmune

130 tain chemotherapeutic drugs stimulate cancer-specific immune responses by inducing immunogenic cell d

131 status does not affect the generation of GP-specific immune responses by these vaccines.

132 duction of robust and long-lasting transgene-specific immune responses by these vectors.

133 In this report we demonstrate that the Gag-specific immune response can be further enhanced by the

134 cterized by the emergence of efficient virus-specific immune responses capable of restraining mutatio

135 despite CD8+ T cell- and B cell-mediated SIV-specific immune responses comparable to those observed i

136 The ovalbumin-specific immune response correlated with clinical respon

137 This study tested whether donor-derived HIV-specific immune responses could be detected when viral r

138 Impaired T. pallidum-specific immune responses could contribute to difference

139 T), HIV loads and frequencies of HIV epitope-specific immune responses decrease.

140 unclear whether this is a location where Ag-specific immune responses develop or merely a site of ly

141 lesion that should be susceptible to an HPV-specific immune response; disease initiation and persist

142 we report that the particularly strong virus-specific immune response during acute primary infection

143 nged mice survival, and the strong antitumor-specific immune response elicited upon poly A:U administ

144 (IRF) 3 and 7 in type I IFN induction and Ag-specific immune responses elicited by DNA vaccination.

145 We further demonstrated that such Ag-specific immune responses elicited by skin LCs were grea

146 ) play a critical role in modulating antigen-specific immune responses elicited by T cells via engage

147 developed attenuated lesions and reduced Ag-specific immune responses following infection with Leish

148 immune regulatory pathways to enhance tumor-specific immune responses for the treatment of cancer ha

149 We compared the HIV-1-specific immune responses generated by targeting HIV-1 e

150 spite this, patients with evidence of a CTAg-specific immune response had a 53% reduction in mortalit

151 ity of antibodies to initiate tumour-antigen-specific immune responses has received less attention th

152 immunocompetent individuals.IMPORTANCE HCMV-specific immune responses have been extensively document

153 rofiles that affect their ability to mediate specific immune responses, here we generated IL-9-skewed

154 y reduced the LNP's ability to boost DEN-80E specific immune responses, highlighting the crucial role

155 e polymorphic nature of PvDBP induces strain-specific immune responses, however, and the epitopes of

156 t PrEP may also allow for development of HIV-specific immune responses, hypothesized to result from a

157 phospholipids and/or sterols, elicit a lung-specific immune response in Abcg1(-/-) mice.

158 (HIV) and hepatitis C virus (HCV) on the HCV-specific immune response in acute HCV infection are limi

159 OIT favorably modified the peanut-specific immune response in all subjects completing the

160 T-OVA showed limited cellular uptake and OVA specific immune response in contrast to short MWNT-OVA d

161 sciatic nerve and to terminate the P0106-125-specific immune response in EAN.

162 ation and specifically CARD11 in the antigen-specific immune response in human subjects.

163 whether PrEP affects the development of HIV-specific immune response in humans.

164 of NDV expressing HIV Gag to generate a Gag-specific immune response in mice.

165 elicited a balanced cellular and humoral GP-specific immune response in mice.

166 ts of oral uptake of Mal d 1 on the allergen-specific immune response in patients with birch pollen a

167 ver, the impact of chemotherapy on the tumor-specific immune response in the context of the tumor mic

168 r compounds from pollen enhance the allergen specific immune response in the skin and nose.

169 T-lymphocytes were used to study the antigen-specific immune response in vitro and in vivo.

170 limiting bystander cell injury during an Ag-specific immune response in vivo are largely unknown.

171 functioned as an adjuvant to augment antigen-specific immune responses in a dose- and cell type-relat

172 ation, viral population structure, and virus-specific immune responses in a longitudinal cohort of 15

173 m abscess formation, and stimulated pathogen-specific immune responses in a mouse model of staphyloco

174 to elicit potent systemic and mucosal virus-specific immune responses in adult nonhuman primates and

175 a (MVA) as a vaccine model, we characterized specific immune responses in all compartments of the FRT

176 ll intrinsic mechanism of evading metastasis-specific immune responses in breast cancer.

177 ic) T cell receptor (TCR) may supplement HBV-specific immune responses in chronic HBV patients and fa

178 ers either the frequency or magnitude of HIV-specific immune responses in HIV-1-exposed seronegative

179 Studies of influenza-specific immune responses in humans have largely assesse

180 onses at steady-state and on M. tuberculosis-specific immune responses in latent TB (LTB), we examine

181 for this apparent protection, we studied HCV-specific immune responses in long-term IDUs (duration, >

182 FRs as important targets for enhancing tumor-specific immune responses in mice and man.

183 We addressed this question by assessing OVA-specific immune responses in mice following hepatocyte t

184 bility of HIV/SIV strategies to induce virus-specific immune responses in milk has not been studied.

185 Enhancement of mucosal HIV-specific immune responses in milk of HIV-infected mother

186 hat the vaccine is capable of inducing virus-specific immune responses in mouse models of acute and c

187 ir efficacy in generating long-term, antigen-specific immune responses in murine and monkey models.

188 e expansion, HBV antigen expression, and HBV-specific immune responses in patients in the immune-tole

189 their potential for inducing robust antigen-specific immune responses in people with prior exposure

190 s by initiating, controlling, and driving Ag-specific immune responses in RA.

191 rotocols that elicited similar levels of Gag-specific immune responses in rhesus macaques.

192 , Konrad et al. present an example of fungus-specific immune responses in social ants that lead to th

193 nd serologically, with generation of antigen-specific immune responses in some cases.

194 steps of B and T cells and started to define specific immune responses in terms of the binding profil

195 es with disease course and evidence of HHV-6-specific immune responses in the CNS provide compelling

196 apacity in vitro and were able to induce OVA-specific immune responses in the lung draining lymph nod

197 organism, Lactococcus lactis, to elicit HIV-specific immune responses in the mucosal and systemic co

198 with coincident DM, we examined mycobacteria-specific immune responses in the whole blood of individu

199 responses were common but did not impair Env-specific immune responses in this study.

200 ty and results in prolonged, robust, antigen-specific immune responses in treated patients.

201 allow the further investigation of human HIV-specific immune responses in vivo and suggests that thes

202 o had diminished ability to induce bacterium-specific immune responses in vivo, as shown by immunoglo

203 caque skin are capable of inducing antiviral-specific immune responses in vivo.

204 ightens the intensity and breadth of antigen-specific immune responses in young and aged mice through

205 er immunotherapeutic approaches induce tumor-specific immune responses, in particular CTL responses,

206 fferent strategies to mount an efficient JCV-specific immune response including TCR bias, HLA cross-r

207 p had greater circumsporozoite protein (CSP)-specific immune responses, including higher immunoglobul

208 ) T cells are detectable among human antigen-specific immune responses, including pathogens such as i

209 pG-Stat3 siRNA generate potent tumor antigen-specific immune responses, increase the ratio of tumor-i

210 The fetal-specific immune response increased during pregnancy and

211 olerogenic regimens by enhancing alloantigen-specific immune responses independently of the generatio

212 e a proper reflection of the M. tuberculosis-specific immune responses induced at the local site of i

213 HIV-1-specific immune responses induced by a dendritic cell (D

214 y reduces Mycobacterium tuberculosis antigen-specific immune responses, induces apoptosis in activate

215 demonstrated that vaccination-induced tumor-specific immune response is associated with superior cli

216 infectious virus from the CNS, and the virus-specific immune response is implicated as a mediator of

217 cells feedback to APCs to sustain an antigen-specific immune response is not completely clear.

218 fferent receptors are coordinated to yield a specific immune response is poorly understood.

219 A CML-specific immune response is thought to contribute to the

220 ur ability to monitor and manipulate antigen-specific immune responses is in its infancy.

221 comparison of infecting genotype and antigen-specific immune responses is possible.

222 RNA levels (elite controllers) have high HIV-specific immune responses, it is unclear whether they ex

223 allograft steatosis influences post-OLT HCV-specific immune responses leading to an IL-17 T-helper r

224 This suggests that the CD4(+) CTAg-specific immune response may play a role in controlling

225 t target immune activation and improve virus-specific immune responses may be needed.

226 s was that ZVIN would elicit significant VZV-specific immune responses, measured by gpELISA or ELISPO

227 We sought to assess the functional, serotype-specific immune response of 12-month-old infants after i

228 Bet v 1-specific immune responses of 16 patients with birch poll

229 human immunodeficiency virus type 1 (HIV-1)-specific immune responses of patients with the HLA-B*57/

230 the effect of erythrocyte polymorphisms and specific immune responses on half-life variation.

231 duration over which control is maintained by specific immune responses open the door to rational desi

232 However, little is known about HIV-1-specific immune responses or inflammation in foreskin.

233 te the ability to generate pathogenic myelin-specific immune responses peripherally, MIF-deficient mi

234 Tissue-specific immune responses play an important role in the

235 We found that SasX induced a specific immune response predominantly based on IgG1 ant

236 ility of viral isolates from ES to evade HIV-specific immune responses probably does not contribute t

237 n heart valve bioprostheses, recipient graft-specific immune responses remain a significant cause of

238 -lymphoid tertiary organs and sustain tissue-specific immune responses remain undefined.

239 Identification of specific immune responses responsible for pathogen prote

240 sis antigen 85B significantly enhanced r30ML-specific immune responses, substantially more so than bo

241 g inflammation, but it can be detrimental in specific immune responses, such as sepsis and antitumor

242 concurrent approaches to favor tumor antigen-specific immune responses, such as vaccines or adoptive

243 ticles elicited significantly higher antigen-specific immune response than "out" nanoparticles and fr

244 he surrounding stroma reflects an anti-tumor-specific immune response that can be altered by stress.

245 study to demonstrate a pre-infection dengue-specific immune response that correlates specifically wi

246 have the potential to induce a conformation-specific immune response that has a function-enhancing r

247 T-II CD4 T cells to track an in vivo antigen-specific immune response that was induced during the cou

248 vaccines may be explained in part by allele-specific immune responses that are directed against poly

249 hat the human airway epithelium mounts virus-specific immune responses that are likely to determine t

250 CD8(+) T cells mediate antigen-specific immune responses that can induce rejection of s

251 ory mediators and initiate adaptive, antigen-specific immune responses that collectively damage glome

252 2F5-epitope scaffolds showed levels of graft-specific immune responses that correlated with graft fle

253 ficacy depends upon the promotion of antigen-specific immune responses that inhibit reactivation or r

254 Alterations in other HIV-specific immune responses that may assist in eliminating

255 logy using sortase A mutants, raised antigen-specific immune responses that protected leukopenic mice

256 thus a great need to define measures of DENV-specific immune responses that reliably indicate when im

257 al trials as cancer vaccines to induce tumor-specific immune responses that will improve clinical out

258 lasts in the blood may contribute to the HIV-specific immune response, the majority of these cells ar

259 In order to generate specific immune responses, the peptides chaperoned by HS

260 Although Tregs inhibit specific immune responses, their inhibition of HIV repli

261 pies that induce beneficial T(H)1-type tumor-specific immune responses, therefore, are highly desirab

262 icity that is instrumental in shaping the Ag-specific immune response to DNA vaccines.

263 Importantly, acquired specific immune response to M. tuberculosis antigens cou

264 mong birds in the effectiveness of their non-specific immune response to MG, and that the host and pa

265 in determining the magnitude of the antigen specific immune response to vaccination with MVA85A in h

266 cluding efficient small RNA delivery and non-specific immune responses to dsRNA.

267 small-animal model with which to study human-specific immune responses to HIV would greatly facilitat

268 t these antigens to generate faster and more specific immune responses to minimize the P. vivax infec

269 f proinflammatory cytokines and delays graft-specific immune responses to prolong islet allograft sur

270 nd the effect of RIG-I activation on antigen-specific immune responses to the encoded antigen was det

271 ubstudy to determine the relationship of VZV-specific immune responses to vaccination and clinical ou

272 HMGN1 promoted antigen-specific immune response upon co-administration with ant

273 FF levels is able to augment a P. aeruginosa-specific immune response upon immunization with heat-kil

274 including APCs in mice, and promoted antigen-specific immune responses upon coadministration with an

275 Here, we studied the EBNA-1-specific immune response using the EBV-homologous rhesus

276 To measure varicella-zoster virus (VZV)-specific immune responses using glycoprotein enzyme-link

277 MHV68) infection, the generation of an MHV68-specific immune response was altered in the absence of A

278 A specific immune response was detected in the bone marrow

279 ability of Hmgn1(-/-) mice to mount antigen-specific immune responses was accompanied by both defici

280 The effect of filarial infections on malaria-specific immune responses was investigated in Malian vil

281 e TB, but the capacity of D-Mtb to stimulate specific immune responses was not investigated.

282 assess the diagnostic potential of pathogen-specific immune responses, we characterized the local re

283 , as well as the capacity to enhance antigen-specific immune responses, we consider EDN to have the p

284 Herein, we investigated whether specific immune responses were correlated with such symp

285 Measles-specific immune responses were evaluated in 70 children

286 Tumor-specific immune responses were induced with dendritic ce

287 HIV-1 reservoirs indicated that their HIV-1-specific immune responses were insufficient to effective

288 High levels of M2e specific immune responses were observed in the 4M2e-tFli

289 HIV and vector-specific immune responses were quantified post-boost vac

290 en lymphocytic choriomeningitis virus (LCMV)-specific immune responses were quantitated, double-mutan

291 Peanut-specific immune responses were serially analyzed.

292 Immunological analysis revealed that HCV-specific immune responses were similarly induced in both

293 es, HBsAg transgenic mice, which show no HBV-specific immune response, were crossed to animals with h

294 such as cytomegalovirus generate huge virus-specific immune responses, which are further expanded in

295 Serotype-specific immune responses, which could promote diversity

296 these compounds to assist the priming of Ag-specific immune responses while minimizing iNKT cell-dep

297 A paucity of data exist comparing xeno-specific immune responses with alloislet (AI) responses

298 ility and the preferential induction of type-specific immune responses with limited potency against h

299 cal coexistence of spontaneous tumor antigen-specific immune responses with progressive disease in ca

300 nctions as a weak but effective adjuvant for specific immune responses, with preferential effects on