ライフサイエンスコーパス: specific pathogen-free

1 rm-free SAMP1/Fc mice examined compared with specific pathogen-free AKR control mice of similar age.

2 we find a large novel subpopulation in both specific pathogen-free and germ-free mice that has not b

3 ometry data from CD8(+) T cells derived from specific pathogen-free and germ-free mice, and stratify

4 n IECs to LC isolated from mice bred in both specific pathogen-free and germfree conditions also resu

5 Young adult specific-pathogen-free and germ-free mice were used to d

6 unctionally compared between germ-free (GF), specific pathogen-free, and GF mice reconstituted with m

7 ntestinal inflammation when maintained under specific pathogen-free animal facility conditions.

8 r three distinct environmental conditions: a specific pathogen-free animal room (SPF), a general anim

9 ittaci B577 antisera, but not with sera from specific-pathogen-free animals.

10 nounced for wheat and soy and occurred under specific pathogen-free as well as germ-free housing cond

11 and colonic lamina propria was determined in specific pathogen-free B6 and TCR transgenic animals, as

12 .hCD46Tg) pig cardiac xenografts survival in specific pathogen free baboons.

13 pared with littermates conventionalized with specific pathogen-free bacteria.

14 ion by Listeria monocytogenes in susceptible specific pathogen-free BALB/c mice.

15 E- and P-selectin (E(-/-)P(-/-)) kept under specific pathogen-free barrier conditions have high circ

16 In this study, when mice housed in a rodent, specific pathogen-free barrier room were challenged with

17 Sixteen specific-pathogen-free beagles were infected with Borrel

18 Twenty 6-week-old specific-pathogen-free beagles were infected with Borrel

19 Eighteen 12-week-old specific pathogen-free cats, blood culture- and serum an

20 Eighteen adult specific pathogen-free cats, vaccinated against FHV-1 se

21 nic infection following blood transfusion in specific-pathogen-free cats and that Bartonella DNA can

22 of the peripheral blood, and of the serum of specific-pathogen-free cats during the acute phase of FI

23 Two-week-old specific-pathogen-free cats infected with FIV-C36 tissue

24 None of the six age- and sex-matched specific-pathogen-free cats inoculated with only T. gond

25 Two groups of four specific-pathogen-free cats were exposed to PLV via the

26 Eighteen specific-pathogen-free cats were inoculated with Bartone

27 nfectivity and pathogenesis, six young adult specific-pathogen-free cats were inoculated with cell-fr

28 d FIP when inoculated intraperitoneally into specific-pathogen-free cats.

29 When specific-pathogen-free chickens were exposed to a pathog

30 Eighty-five 60-week-old specific-pathogen-free chickens were randomly divided in

31 Vaccination of specific-pathogen-free chickens with these recombinant v

32 7A PT 8 in birds from vaccinated hens and in specific-pathogen-free chickens.

33 a strain which prevents the colonization of specific-pathogen-free chicks by Clostridium perfringens

34 and their wild-type littermates reared under specific pathogen-free condition with aging.

35 This inflammatory disorder occurs under specific pathogen-free conditions and critically involve

36 -negative mice in germ-free (GF), but not in specific pathogen-free conditions develop the disease.

37 antibiotic treatment or breeding mice under specific pathogen-free conditions did not reduce AMP exp

38 antibiotic treatment or breeding mice under specific pathogen-free conditions did not reduce AMP exp

39 e skin of asymptomatic NC/Tnd mice housed in specific pathogen-free conditions induced kallikrein 5 a

40 tly enteric bacteria, even when reared under specific pathogen-free conditions with antibiotics.

41 mdx and wild-type C57BL/10 mice housed under specific pathogen-free conditions with deaths restricted

42 s microbial environment in mice housed under specific pathogen-free conditions, and the lack of pharm

43 When housed in specific pathogen-free conditions, dbh-/- mice had norma

44 mice remained healthy when maintained under specific pathogen-free conditions.

45 Cd1d-/- mice in comparison to WT mice under specific pathogen-free conditions.

46 Fecal transplants from mice reared in specific-pathogen-free conditions into germ-free Nlrp12-

47 infected with H. bilis Missouri strain under specific-pathogen-free conditions, followed by an intrav

48 Although healthy in specific-pathogen-free conditions, Il10(-/-); Nod2(-/-)

49 us carcinogenesis in FVB/N mice housed under specific-pathogen-free conditions.

50 ce on a uniform C57BL/6 background housed in specific-pathogen-free conditions.

51 3L, SCF, and ThPO to the levels displayed by specific pathogen-free control animals.

52 severe hemolytic anemia when inoculated into specific-pathogen-free-derived cats.

53 In specific-pathogen-free dogs experimentally infected with

54 Germfree transgenic rats were colonized with specific-pathogen-free enteric bacteria grown overnight

55 ged by a conventional environment, mice in a specific pathogen-free environment had less IgA depositi

56 DM incidence at 7 months for these mice in a specific pathogen-free environment on the respective die

57 use of antibiotic (Bactrim) prophylaxis in a specific pathogen-free environment, however, impedes inf

58 jugated keyhole limpet hemocyanin (KLH) in a specific pathogen-free environment.

59 with specified bacteria, and mice housed in specific pathogen-free environments.

60 NOD2-/- and C57BL/6J mice, maintained in a specific pathogen-free facility, were given antibiotics,

61 L/lpr genetic background and maintained in a specific pathogen-free facility.

62 colonization of the ferret stomach, ferrets specific pathogen free for H. mustelae were inoculated w

63 e of infection with H. mustelae, 19 ferrets, specific pathogen free for H. mustelae, were given eithe

64 cecum was excluded from the fecal stream in specific pathogen-free HLA-B27 transgenic (TG) rats with

65 body weight as the wild type mice under our specific pathogen-free housing condition and showed no s

66 us ileitis and colitis after 16 mo of age in specific pathogen-free housing conditions.

67 Specific pathogen-free IL-10 KO mice failed to develop i

68 We have previously shown that specific pathogen-free IL-10-deficient (IL-10 KO) mice d

69 Germ-free and specific pathogen-free Il10(-/-) and germ-free Il10(-/-)

70 Specific-pathogen-free Il10(-/-), Nod2(-/-), and Il10(-/

71 een a TH2 response and immune suppression in specific-pathogen-free inbred cotton rats which were inf

72 We have previously shown that specific-pathogen-free interleukin-10 (IL-10)-deficient

73 leukin-17 prevented arthritis development in specific-pathogen-free K/BxN mice resulting from a direc

74 n, suggesting that many, if not most, TCE in specific pathogen-free laboratory mice may be Ag-indepen

75 endent T cell clonal expansions found in old specific pathogen-free laboratory mice.

76 from sheep clinically free of OEA, and from specific-pathogen-free lambs experimentally infected wit

77 inistered to eight cesarean section-derived, specific-pathogen-free macaques 14 to 42 days of age.

78 Specific pathogen-free male Sprague Dawley rats.

79 This hypothesis was tested in alcohol-fed, specific pathogen-free, male Sprague-Dawley rats.

80 thesized that a critical distinction between specific pathogen-free mice and nonhuman primates or hum

81 However, serum IgA of specific pathogen-free mice showed more galactosylation

82 elative increase in PP after PPVL in ASF and specific pathogen-free mice was not significantly differ

83 inal epithelial cells and dendritic cells of specific pathogen-free mice, expressed much lower levels

84 Specific pathogen-free mice, obtained from different ven

85 f resident gammadelta T cells in the SLOs of specific pathogen-free mice.

86 and allergic asthma as compared with that of specific pathogen-free mice.

87 iveness of TCE, which arise spontaneously in specific pathogen-free mice.

88 Alveolar bone resorption can be induced in specific-pathogen-free mice by oral infection with Porph

89 sterix) and Igf1 in bone, and serum IGF1, in specific-pathogen-free mice suggest the commensal microb

90 ogel, whereas exposure to luminal fluid from specific-pathogen-free mice-whose microbiota degrade gut

91 iota, and that exposure to the microbiota of specific pathogen-free MyD88-negative NOD donors attenua

92 d development of eczematous lesions in these specific pathogen-free NC/Tnd mice, which normally do no

93 etin also induced scratching behavior in the specific pathogen-free NC/Tnd mice.

94 enome sequence, and in vivo pathogenicity in specific-pathogen-free newborn cats.

95 Here we show that specific pathogen-free NOD mice lacking MyD88 protein (a

96 e the harboring of Helicobacter species [non-specific-pathogen-free (non-SPF) conditions].

97 In specific pathogen-free nonobese diabetic (NOD) mice, fem

98 We observed that under specific pathogen-free or germ-free conditions, intragas

99 A total of 48 specific-pathogen-free piglets were randomly and equally

100 Forty specific-pathogen-free pigs at 4 weeks of age were rando

101 Furthermore, in a reciprocal experiment, specific-pathogen-free pigs were experimentally infected

102 Specific-pathogen-free pigs were inoculated with one of

103 erimentally characterize the VP120 virus, 31 specific-pathogen-free pigs were randomly divided into t

104 uced by M. bovis BCG vaccination, 4-week-old specific-pathogen-free pigs were vaccinated with M. bovi

105 n an early study, we experimentally infected specific-pathogen-free pigs with two strains of HEV: swi

106 ential of these organisms was evaluated in a specific-pathogen-free rat model in which the feeding pa

107 Specific-pathogen-free rats that were infected with ACUS

108 Four groups of specific-pathogen-free rats were formed: S. mutans 10449

109 ced into a Helicobacter hepaticus-containing specific pathogen-free room, these lesions reappear.

110 mice, although it was attenuated relative to specific pathogen-free SAMP1/Fc mice.

111 Laboratory mice live in abnormally hygienic specific pathogen free (SPF) barrier facilities.

112 fferent microbiota: restricted flora (RF) vs specific pathogen free (SPF).

113 ngredients, nutrients, and the microbiota in specific pathogen-free (SPF) and germ-free (GF) mice giv

114 Specific pathogen-free (SPF) C57BL/6J or germfree 129S6/

115 trosourea (ENU), numerous animals died under specific pathogen-free (SPF) conditions between 6 and 7

116 Also, WT mice raised in specific pathogen-free (SPF) conditions fared better aga

117 e skin of asymptomatic NC/Tnd mice housed in specific pathogen-free (SPF) conditions induced KLK5 and

118 ow (BM-->Tg(epsilon26)) causes colitis under specific pathogen-free (SPF) conditions.

119 mature germ-free (GF) mice with conventional specific pathogen-free (SPF) gut microbiota increases bo

120 lized autoimmunity, similar to those seen in specific pathogen-free (SPF) IL-2(-/-) mice.

121 Microbiota composition of specific pathogen-free (SPF) INS-GAS mice was quantified

122 Specific Pathogen-Free (SPF) layer chickens were infecte

123 n and tumors in GF and conventionally raised specific pathogen-free (SPF) mice treated with azoxymeth

124 inflammation that develops spontaneously in specific pathogen-free (SPF) mice with a targeted disrup

125 We found that, in sharp contrast to specific pathogen-free (SPF) mice, germ-free (GF) mice a

126 However, compared with disease in specific pathogen-free (SPF) mice, ileitis in GF mice is

127 m-free zebrafish embryos were colonized with specific pathogen-free (SPF) microbiota.

128 H pylori-specific pathogen-free (SPF) monkeys were experimentally

129 prone BioBreeding (BBdp) rats were housed in specific pathogen-free (SPF) or germ-free (GF) condition

130 ation of T cells adoptively transferred into specific pathogen-free (SPF) RAG-/- mice, but not in ger

131 Cohorts were transferred from specific pathogen-free (SPF) to conventional (non-SPF) a

132 inhibitor ezetimibe reduces stool output in specific pathogen-free (SPF), but not GF mice.

133 (WT) colonic macrophages from germ-free and specific pathogen-free (SPF)-derived mice produce IL-10,

134 Bile and feces collected from specific-pathogen-free (SPF) chickens experimentally inf

135 d by clinicopathological characterization in specific-pathogen-free (SPF) chickens.

136 inal inflammatory response when reared under specific-pathogen-free (SPF) conditions, suggesting the

137 itions but develop only colitis when kept in specific-pathogen-free (SPF) environments.

138 Five specific-pathogen-free (SPF) Helicobacter-free cats were

139 (IL-10(-/-) mice) and potentiate colitis in specific-pathogen-free (SPF) IL-10(-/-) mice.

140 cattery cats and transferring these fleas to specific-pathogen-free (SPF) kittens housed in a control

141 Germ-free mice, clean specific-pathogen-free (SPF) mice colonized with a micro

142 ent comparisons of germ-free (GF) and normal specific-pathogen-free (SPF) mice have revealed the impa

143 c(Min/+) ;Il10(-/-) mice and exposed them to specific-pathogen-free (SPF) or colorectal cancer-associ

144 Moreover, the development of specific-pathogen-free (SPF) oysters has enabled assessm

145 hogenicities of the mutants, we utilized the specific-pathogen-free (SPF) pig model for HEV and a uni

146 ty of the chimeric infectious DNA clones, 40 specific-pathogen-free (SPF) pigs were randomly assigned

147 in the upper and lower respiratory tracts of specific-pathogen-free (SPF) young turkeys.

148 Male specific pathogen-free Sprague-Dawley rats.

149 Specific pathogen-free Sprague-Dawley rats.

150 re viable and fertile in a controlled-access specific-pathogen-free vivarium, showed no major morphol