ライフサイエンスコーパス: speckle

1 rojection due to coherent artifacts, such as speckle.

2 ntly labeled single molecule from background speckle.

3 ly only after initial contact with a nuclear speckle.

4 sharpness and the temporal coherence to the speckle.

5 patterns: minimal change, focal, patchy, and speckled.

6 on of chromosomes, k-fibers, and microtubule speckles.

7 een them, indicate they associate at nuclear speckles.

8 horylated SC35, which is retained in nuclear speckles.

9 ompartment enriched in SC35-positive nuclear speckles.

10 at1, a large ncRNA that localizes to nuclear speckles.

11 for HSP70 transgenes associated with nuclear speckles.

12 s and in a higher number of enlarged nuclear speckles.

13 and RNA-binding protein localized in nuclear speckles.

14 was exclusively present in nuclear bodies or speckles.

15 taining between PABP1 and markers of nuclear speckles.

16 sembly of mRNA processing factors in nuclear speckles.

17 2 entry into the nucleus and accumulation in speckles.

18 of targeting the resulting fusion protein to speckles.

19 NA components in the organization of nuclear speckles.

20 e speckle-type POZ protein (SPOP) to nuclear speckles.

21 es by utilising the remarkable properties of speckles.

22 Here, we report that the PML-NB protein Speckled 110 kDa (Sp110) is SUMO1-modified and undergoes

23 ocytic leukemia nuclear bodies (38), nuclear speckles (27), paraspeckles (24), Cajal bodies (17), Sam

24 teristic subnuclear KSHV microdomains ("LANA speckles"), a hallmark of KSHV latency.

25 protein 39 (RBM39) and localizes to nuclear speckles adjacent to spliceosomes.

26 association of HSP70 transgenes with nuclear speckles after heat shock.

27 activation in transgenes not associated with speckles, although robust transcriptional activation was

28 retinal nerve fiber layer (RNFL) reflectance speckle and tested the hypothesis that temporal change o

29 Patients with speckled and focal patterns showed limited or no changes

30 SMAR1 is enriched in nuclear splicing speckles and associates with the snRNAs that are involve

31 Accumulation of HIPK2 in nuclear speckles and association with promyelocytic leukemia pro

32 e association of splicing factors to nuclear speckles and influences the levels and activity of other

33 fluorescent protein-labeled cortical dynein speckles and motile microtubules.

34 SR proteins mediate the assembly of nuclear speckles and regulate gene expression by influencing bot

35 is based on correlation of X-ray near-field speckles and represents a significant broadening of the

36 on with Pi04089, its localization to nuclear speckles, and its increased accumulation when co-express

37 PCBP1 to colocalize in SC35-positive nuclear speckles, and the two proteins interact in the variable

38 yed close localization in and around nuclear speckles, and their physical association in protein comp

39 Although the image sharpness and speckle are related to both coherence parameters, our re

40 ical substrate Gli3, suggesting that nuclear speckles are hotspots of ubiquitination.

41 Given that nuclear speckles are storage sites for splicing factors, which l

42 Since nuclear speckles are storage sites for splicing factors, which l

43 Nuclear speckles are subnuclear domains that contain pre-mRNA pr

44 Moreover, blocking new HSP70 transgene/speckle association by actin depolymerization prevented

45 o transcriptional activation; moreover, this speckle association enhances the heat shock activation o

46 p150glued) form spatially resolved, dynamic speckles at the cell cortex, which are preferentially as

47 Recently, an X-ray speckle-based technique has shown great potential for X-

48 ocalizations can be also excited by extended speckled beams.

49 f stimulated emission and do not suffer from speckle, but are rather broadband and have a relatively

50 ted the translocation of M1 to SC35-positive speckles, but did not interfere with PB2 localization to

51 surement of the optical properties where the speckle can severely distort the information.

52 ding nucleoli, the nuclear envelope, nuclear speckles, centrosomes, mitochondria, the endoplasmic ret

53 SmD1b resides in nucleoli and nucleoplasmic speckles, colocalizing with the splicing-related factor

54 Many of the nuclear speckle constituents work in concert to coordinate multi

55 aments in rng8(+) cells, whereas Myo51 forms speckles containing only one dimer and does not move eff

56 r with SUMO1 and SUMO2 into enlarged nuclear speckles containing polyadenylated RNA.

57 in which synchronized dual wavelength laser speckle contrast imaging (DWLS) was used as a guiding to

58 Here, we present Laser Speckle Contrast Imaging (LSCI) for real-time assessment

59 Functional performance of laser speckle contrast imaging (LSCI) systems is compromised b

60 wound cutaneous blood flow measured by laser speckle contrast imaging (p=0.0002), corroborated by inc

61 o a ministroke that was verified using laser speckle contrast imaging.

62 tometer, and microvascular function by laser speckle contrast imaging.

63 oducing inverse variance in conjunction with speckle contrast in Matlab-based program code.

64 inside a dynamic scattering medium having a speckle correlation time as short as 5.6 ms, typical of

65 ads to sequestration of PABP1 in the nuclear speckles, creating a state within the cell that favors v

66 tt103Q accumulates in unassembled states and speckled cytosolic foci.

67 In contrast, RV longitudinal systolic speckle-derived strain measures were significantly diffe

68 Speckle-derived strain of the right ventricle (RV) was u

69 Speckle-derived strain reveals a heterogenous pattern of

70 RV longitudinal systolic speckle-derived strain was assessed in the basal, mid, a

71 o large spliceosome assembly factor-positive speckle domains within the nuclei.

72 alization of proteins to sites peripheral to speckled domains.

73 Although heavy females laid paler, less speckled eggs, these eggs did not produce chicks that gr

74 tionary competition among optical modes, the speckle field develops a single, high intensity focus si

75 ain optical coherence tomography and a laser speckle flowgraphy device (LSFG), respectively.

76 ced cerebral oligemia, we used in vivo laser speckle flowmetry and multimodal imaging.

77 aging and larger perfusion deficits on laser speckle flowmetry.

78 times (tens of seconds) approaching those of speckle fluorescence methods.

79 sing process degrades the image quality with speckle formation.

80 The two Rbm20 speckles found in nuclei from muscle tissues were identi

81 t source with unprecedented brightness for a speckle-free and narrowband light source.

82 Speckle-free full-field imaging is demonstrated using th

83 pulsed random laser for fiber-optic sensing, speckle-free imaging, and laser-material processing, but

84 including random lasers, light storage, and speckle-free imaging.

85 que will provide a unique solution for a low-speckle, full-field, and coherent imaging in optically s

86 high-speed camera acquires the time-varying speckle images.

87 This inducible speckle imaging (ISI) technique allows 3D speckle micros

88 d choroidal blood flow was measured by laser speckle imaging and laser Doppler flowmetry, respectivel

89 e used in vivo multiphoton microscopy, laser speckle imaging of CBF, and electrophysiological recordi

90 ase modulation was implemented for the lower speckle imaging with over a 50% speckle reduction withou

91 oes not preclude conventional imaging before speckle imaging.

92 translates into a 40% remaining signal after speckle imprinting and provides a rule of thumb in selec

93 We predict theoretically that speckle imprinting using photobleaching is optimal when

94 ss induces the release of SF3B1 from nuclear speckles in a manner that depends on FANCI and on the ac

95 associated foci and SC35-containing splicing speckles in a transcription-dependent manner, whereas in

96 lasmic staining in neurons and labeled large speckles in cerebellar Purkinje cells.

97 ys revealed the emergence of H3K9me2 nuclear speckles in committed HSPCs, consistent with progressive

98 rect path over long distances toward nuclear speckles in response to transcriptional activation; more

99 tes the formation and maintenance of nuclear speckles in the interphase nucleus is poorly understood.

100 1 RNA, can nucleate the assembly of nuclear speckles in the interphase nucleus.

101 nlikely explanation for the evolution of egg speckling in great tits.

102 identical arrangement of the characteristic speckles inside the particles.

103 s-correlation analysis of frames returns the speckle intensity autocorrelation function, g2(t), from

104 he scleral surface were measured using laser speckle interferometry.

105 the inhibitors resulted in dispersal of the speckles into smaller foci with subsequent apoptosis ind

106 ique in which the displacement of near field speckle is tracked using a digital image correlation alg

107 p TNNT3 pre-mRNA, driving it outside nuclear speckles, leading to an altered SC35-mediated splicing.

108 ave shown a broad distribution of EGFP-actin speckle lifetimes and indicated actin polymerization and

109 V 3'UTR redistributes DDX3X and IKK-alpha to speckle-like cytoplasmic structures shown to be SGs.

110 h DDX3X and IKK-alpha, which redistribute to speckle-like cytoplasmic structures shown to be stress g

111 e exclusive protein nuclear localization and speckle-like distribution.

112 siRNA resulted in a decrease in the nuclear speckle localization of WTAP, whereas the nuclear speckl

113 Assessment of RNFL reflectance speckle may offer a new means of evaluating axonal funct

114 of active genes at their periphery suggests speckles may play a role in gene expression [3, 4].

115 ay that targets the viral M1 mRNA to nuclear speckles, mediates splicing at these nuclear bodies and

116 ay that targets the viral M1 mRNA to nuclear speckles, mediates splicing at these nuclear bodies, and

117 Using fluorescent speckle microscopy (FSM), differential interference cont

118 Methods such as fluorescent speckle microscopy and spatial temporal image correlatio

119 Furthermore, fluorescent speckle microscopy revealed that detached kinetochores c

120 Fluorescent speckle microscopy revealed that rates of actin assembly

121 le speckle imaging (ISI) technique allows 3D speckle microscopy to be performed in readily available

122 We used speckle microscopy to demonstrate that MTs experience re

123 e describe the basic concepts of fluorescent speckle microscopy, total internal reflection fluorescen

124 l vorticity or net polymerization rates from speckle microscopy.

125 results in two dimensions using fluorescent speckle microscopy.

126 ast relative to classic (random) fluorescent speckle microscopy.

127 urbulent quantum gas and a traveling optical speckle might burgeon into an exciting research field in

128 values were computed by using the Lagrangian speckle model estimator.

129 Here we show speckle-modulating OCT (SM-OCT), a method based purely o

130 tions such as Gaussian noise, Poisson noise, speckle noise and pupil location error, which would larg

131 light manipulation that virtually eliminates speckle noise originating from a sample.

132 match the corresponding Cirrus data format, speckle noise reduction and amplitude normalization were

133 wever, it also causes unavoidable background speckle noise thus degrades the image quality in traditi

134 ncoherent, resulting in negligible amount of speckle noise upon decryption.

135 skin-features that are otherwise obscured by speckle noise when using conventional OCT or OCT with cu

136 uence, OCT is susceptible to coherent noise (speckle noise), which imposes significant limitations on

137 RNFL reflectance speckle of isolated rat retinas was studied with monochr

138 inetics at the cell cortex reveal that these speckles often contain multiple labeled dynein heavy-cha

139 In elongating spermatids, CnnT forms speckles on the giant mitochondria that are required to

140 Nuclear speckles, or interchromatin granule clusters, are enrich

141 ansgenes moving curvilinearly toward nuclear speckles over approximately 0.5-6 mum distances at veloc

142 ed by two to four times, indicating that the speckle pattern changed more slowly.

143 n, the magnetic domains in [Co/Pd] produce a speckle pattern, a unique fingerprint of their nanoscale

144 instein condensate and a propagating optical speckle pattern.

145 urse was used to evaluate temporal change of speckle pattern.

146 Our straightforward analysis of laser speckle patterns across the first order phase transition

147 By analysing small-angle X-ray scattering speckle patterns from colloidal dispersions we found a d

148 ated wavefronts, and the resulting intensity speckle patterns in the transmitted light are acquired o

149 Speckle patterns resulting from the interference of mult

150 We measure MDM by cross-correlating speckle patterns throughout magnetization processes.

151 unlimited number of scans with uncorrelated speckle patterns without compromising spatial resolution

152 ting sphere to generate wavelength-dependent speckle patterns, in combination with algorithms based o

153 Moreover, this "speckle periphery-targeting signal" contributes to the r

154 rine birds lay white eggs with reddish brown speckles produced by protoporphyrin pigment.

155 nal OCT or OCT with current state of the art speckle reduction methods.

156 or the lower speckle imaging with over a 50% speckle reduction without a significant degradation in t

157 C5 and co-localization with MEF2s in nuclear speckles requiring serine residues 259 and 498, whose ph

158 vide evidence for the involvement of nuclear speckle resident proteins and RNA components in the orga

159 ocation to the nucleoplasm and SC35-positive speckles, respectively, even though CLUH is usually cyto

160 the hypothesis that temporal change of RNFL speckle reveals axonal dynamic activity.

161 s study suggest that temporal change of RNFL speckle reveals structural change due to axonal activity

162 Laser Speckle Rheology (LSR) offers a novel, non-contact optic

163 Here, we show that the nuclear speckle RNA-binding protein (NSR) and the AS competitor

164 e-rich yeast prion [RNQ+] while reorganizing speckled Rnq1-monomeric red fluorescent protein into dis

165 pecies, English sole (Parophrys vetulus) and speckled sanddab (Citharichthys stigmaeus).

166 imaging with diffuse light at unprecedented, speckle-scale lateral resolution of ~ 5 mum.

167 e wild-type SPOP localizes to liquid nuclear speckles, self-association-deficient SPOP mutants have a

168 fluorescent speckles significantly improves speckle signal and contrast relative to classic (random)

169 inting of three-dimensional (3D) fluorescent speckles significantly improves speckle signal and contr

170 ng edge of motile cells with single-molecule speckle (SiMS) microscopy have shown a broad distributio

171 Combining a microscopic analysis of speckle-speckle correlations with an effective coarse-gr

172 positive; 96% of ANA positives had a nuclear speckled staining pattern.

173 We used speckle statistics obtained by SiMS to model the steady-

174 In addition to standard echocardiography, speckle strain was measured to assess GLS.

175 on, is influenced by association with dynein speckles, suggesting a direct physical and functional in

176 onomeric actin probes concentrate in nuclear speckles, suggesting an interaction of monomers with RNA

177 luding U2AF65B, U2A', and U2AF35A in nuclear speckles, suggesting SFPS might be involved in the 3' sp

178 uclear noncanonical poly(A) polymerase (PAP) speckle targeted PIPKIalpha regulated PAP (Star-PAP) con

179 The speckled texture in fixed retina was stationary.

180 ot uniform; rather nerve fiber bundles had a speckled texture that changed with time.

181 n of Nrd1 and the formation of novel nuclear speckles that contain Nrd1 and Nab3.

182 To relate temporal change of speckle to axonal activity, in vitro living retina perfu

183 e show that the influenza virus uses nuclear speckles to promote post-transcriptional splicing of its

184 e show that influenza virus utilizes nuclear speckles to promote post-transcriptional splicing of its

185 we reveal a functional subversion of nuclear speckles to promote viral gene expression.

186 we reveal a functional subversion of nuclear speckles to promote viral gene expression.

187 -arginine (SR) proteins from nuclear storage speckles to the nucleoplasm for splicing function, depho

188 on indices were obtained using 2-dimensional speckle tracking (2DCPA; TomTec, Germany).

189 sis, validation data of two-dimensional (2D) speckle tracking (2DST) echocardiography myocardial stra

190 mine if parameters obtained by 2-dimensional speckle tracking (2DST) were affected by acute changes i

191 Three-dimensional speckle tracking (3D-ST) has been used extensively to qu

192 work is hardware vendor independent and uses speckle tracking (endocardial border detection) on ultra

193 Speckle tracking accurately measures myocardial deformat

194 Using two-dimensional echocardiography and speckle tracking analysis, this study compared LV mechan

195 ean age, 47.4+/-9.9 years) were eligible for speckle tracking analysis.

196 We compared traditional echo, 2-dimensional speckle tracking and catheterization-derived parameters

197 Subjects underwent echocardiography with speckle tracking and contrast-enhanced cardiac MRI with

198 Together, these data support speckle tracking as a postprocessing echocardiographic t

199 The Speckle Tracking Assisted Resynchronization Therapy for

200 2-dimensional strain parameters measured by speckle tracking at rest and during dobutamine stress ec

201 diography with myocardial strain measured by speckle tracking during the Year-25 examination (age, 43

202 cardial changes during therapy, whereas with speckle tracking echocardiography (STE), peak systolic g

203 advanced imaging modalities, including both speckle tracking echocardiography and tissue tracking by

204 d dogs we measured UTR by sonomicrometry and speckle tracking echocardiography at varying LV preloads

205 chocardiography including tissue Doppler and speckle tracking echocardiography before and after LTx.

206 and recalling multidimensional attributes of speckle tracking echocardiography data sets derived from

207 The speckle tracking echocardiography data were normalized i

208 Using only speckle tracking echocardiography variables, associative

209 ent standard echocardiography, 3-dimensional speckle tracking echocardiography, and cardiac magnetic

210 site of latest time to peak radial strain by speckle tracking echocardiography.

211 , longitudinal septal strain was assessed by speckle tracking echocardiography.

212 Techniques of 2-dimensional speckle tracking enable the measurement of myocardial de

213 in the septum was assessed by 2-dimensional speckle tracking imaging.

214 unction (LA total strain) were measured from speckle tracking in 2 groups.

215 al mechanics were evaluated by 2-dimensional speckle tracking in 52 consecutive patients with CP who

216 (RA late LS rate) phases were assessed by 2D speckle tracking in 65 patients with PAH, 6-minute walk

217 We measured GLS by 2-dimensional speckle tracking in the apical 4-chamber view in 791 par

218 Low GLS measured by 2-dimensional speckle tracking predicts future cardiovascular events i

219 hod is based on the recently developed X-ray speckle tracking technique in which the displacement of

220 Phase-sensitive speckle tracking was applied to reconstruct TS maps core

221 tolic global longitudinal strain by means of speckle tracking was assessed with same-day transthoraci

222 Rotational strain measured by speckle tracking was compared in 32 children after OHT,

223 action (EF) by planimetry and peak GLS by 2D speckle tracking were available at admission in 115 of 1

224 onventional ultrasonography, two-dimensional speckle tracking, and cardiac magnetic resonance (CMR) T

225 ography including tissue-Doppler imaging and speckle tracking, and cardiovascular magnetic resonance.

226 chocardiography with tissue Doppler imaging, speckle tracking, and three-dimensional echocardiography

227 The speckle tracking, border detection and model fitting met

228 Speckle tracking-based deformation as a feasible and sen

229 and time-based dyssynchrony were assessed by speckle tracking.

230 diography with myocardial strain measured by speckle tracking.

231 train, peak twisting, untwisting velocity by speckle tracking; and (4) interleukin-1beta, nitrotyrosi

232 for CRT underwent baseline echocardiographic speckle-tracking 2-dimensional radial strain imaging and

233 We performed speckle-tracking analysis of echocardiograms from partic

234 We performed speckle-tracking analysis on HyperGEN (Hypertension Gene

235 lobal longitudinal strain was measured using speckle-tracking analysis.

236 After adjusting for speckle-tracking analyst, image quality, study site, age

237 nction were assessed by echocardiography and speckle-tracking based strain imaging.

238 rial-Cardiac Resynchronization Therapy) with speckle-tracking data available.

239 We performed speckle-tracking echocardiographic analysis to quantify

240 machine-learning framework that incorporates speckle-tracking echocardiographic data for automated di

241 Expert-annotated speckle-tracking echocardiographic datasets obtained fro

242 e hypothesis that contractile function using speckle-tracking echocardiographic global circumferentia

243 s; 14 men) and 20 control subjects underwent speckle-tracking echocardiographic measurement of longit

244 LS was assessed by 2-dimensional speckle-tracking echocardiography at baseline in 447 pat

245 All patients underwent speckle-tracking echocardiography for measurement of lef

246 Strain measurements using speckle-tracking echocardiography have been used to sens

247 We assessed LA function measured by speckle-tracking echocardiography in 357 patients with H

248 F and GLS were assessed by 2-dimensional and speckle-tracking echocardiography in 439 participants fr

249 This review appraised speckle-tracking echocardiography in a clinical context

250 Using speckle-tracking echocardiography in two rat models of u

251 lity and sensitivity of strain imaging using speckle-tracking echocardiography in women with preeclam

252 We investigated whether speckle-tracking echocardiography is superior to routine

253 ures of regional longitudinal deformation by speckle-tracking echocardiography predict ventricular ta

254 We hypothesized that RV strain measured by speckle-tracking echocardiography predicts outcome in PH

255 Speckle-tracking echocardiography revealed significant r

256 ared with standard CRT treatment, the use of speckle-tracking echocardiography to the target LV lead

257 +/- 0.6 cm, P = 0.163), and two-dimensional speckle-tracking echocardiography was used to assess LV

258 easures study design using 2-dimensional and speckle-tracking echocardiography was used to examine ac

259 Speckle-tracking echocardiography was used to measure LV

260 2-dimensional, Doppler, tissue Doppler, and speckle-tracking echocardiography will be performed unif

261 n-based imaging techniques (and specifically speckle-tracking echocardiography) have been shown to ha

262 ing at mitral valve opening (%untwMVO) using speckle-tracking echocardiography, (2) coronary flow res

263 y foster the implementation of 2-dimensional speckle-tracking echocardiography-derived RV analysis in

264 ardiac deformation was assessed in detail by speckle-tracking echocardiography.

265 deformation was assessed by two-dimensional speckle-tracking echocardiography.

266 seline LVGLS was measured with 2-dimensional speckle-tracking echocardiography.

267 ons from all LV segments using 2-dimensional speckle-tracking echocardiography.

268 udinal direction, which can be assessed with speckle-tracking echocardiography.

269 l strain were calculated using 2-dimensional speckle-tracking echocardiography.

270 e reference values for RVLS by 2-dimensional speckle-tracking echocardiography; and (2) their relatio

271 ion was assessed by LV ejection fraction and speckle-tracking GLS.

272 Standard measures of LV function and speckle-tracking imaging worsened as wall thickness incr

273 standard echocardiography and 2-dimensional speckle-tracking imaging-derived left ventricular (LV) l

274 art failure was resolved prospectively using speckle-tracking imaging.

275 e, tricuspid annular plane excursion, and RV speckle-tracking longitudinal strain.

276 sed using a vendor-independent 2-dimensional speckle-tracking software.

277 association with LV filling patterns through speckle-tracking strain echocardiography.

278 In particular, we discuss the use of speckle-tracking strain in selected areas, such as undif

279 tients without AF history were evaluated by (speckle-tracking) echocardiography.

280 We performed speckle-tracking-based echocardiographic measures of lef

281 chocardiographic analytical method, based on speckle-tracking-based strain analyses, and used this to

282 strated that the E3 ubiquitin ligase adaptor speckle-type poxvirus and zinc finger (POZ) domain prote

283 ng cyclin D-CDK4-mediated phosphorylation of speckle-type POZ protein (SPOP) and thereby promoting SP

284 tate cancer-specific somatic mutation in the Speckle-Type POZ protein (SPOP) gene.

285 The E3 ubiquitin ligase adaptor speckle-type POZ protein (SPOP) is frequently dysregulat

286 3 ubiquitin ligase substrate-binding adaptor speckle-type POZ protein (SPOP) is the most frequently m

287 e show that recurrent PC-driver mutations in speckle-type POZ protein (SPOP) stabilize the TRIM24 pro

288 assemblies influences the recruitment of the speckle-type POZ protein (SPOP) to nuclear speckles.

289 Gli/Ci turnover by preventing degradation of speckle-type POZ protein (Spop), a protein that promotes

290 Previous in vitro studies suggested that Speckle-type POZ protein (Spop), part of the Cullin-3 (C

291 tin-dependent movement of HSP70 loci towards speckles upon heat shock, resulting in enhanced transcri

292 vestigate the cilia-driven flow field and 3D speckle variance imaging to investigate size and extent

293 Speckle variance OCT-A allows visualization and quantifi

294 Using this speckle wavemeter as part of a feedback loop, we stabili

295 le localization of WTAP, whereas the nuclear speckles were intact.

296 ect this protein to the periphery of nuclear speckles, where coordinated transcription/RNA processing

297 t T1L, but not T3D, mu2 localizes to nuclear speckles, where it forms a complex with the mRNA splicin

298 a protein variant that localizes to nuclear speckles, where it targets a cell mRNA splicing factor.

299 statin A leads to the reorganization of SC35 speckles, which is closely mirrored by Pat1b, indicating

300 of species' habitat associations, using the speckled wood butterfly, Pararge aegeria, in Britain, as