ライフサイエンスコーパス: spectinomycin

1 yme A carboxylase, cause hypersensitivity to spectinomycin.

2 effective as selection on medium containing spectinomycin.

3 nfers bacterial resistance to the antibiotic spectinomycin.

4 ith some minor variations for ampicillin and spectinomycin.

5 rs that produce resistance to the antibiotic spectinomycin.

6 Exogenous addition of spectinomycin, a bacteriostatic antibiotic, rescued the

7 plastomic clones is ensured by selection for spectinomycin (aadA) or kanamycin (neo) resistance genes

8 nic and encode genes for herbicide (bar) and spectinomycin (aadA) resistance.

9 findings also explain the mode of action of spectinomycin, an antibiotic that blocks translocation b

10 onses of different Arabidopsis accessions on spectinomycin, an inhibitor of chloroplast translation,

11 s without mutagenesis by a short exposure to spectinomycin, an inhibitor of plastid protein synthesis

12 , we generated a new semisynthetic series of spectinomycin analogs with selective ribosomal inhibitio

13 reased mutation rate to these antibiotics or spectinomycin and kasugamycin.

14 promoter-aadA cassette confers resistance to spectinomycin and streptomycin in both B. burgdorferi an

15 ch confers resistance to the aminoglycosides spectinomycin and streptomycin in Escherchia coli, can b

16 nt with FLARE-S vector DNA and selection for spectinomycin and streptomycin resistance, respectively.

17 ing the aadA gene that confers resistance to spectinomycin and streptomycin, has been considered crit

18 B8; and gene aadA1, conferring resistance to spectinomycin and streptomycin, was associated with an O

19 rase domain appears to be highly specific to spectinomycin and streptomycin, while the acetyltransfer

20 and gene aadA1a, which confers resistance to spectinomycin and streptomycin.

21 lity to confer resistance to the antibiotics spectinomycin and streptomycin.

22 which confers resistance to the antibiotics spectinomycin and streptomycin.

23 sferase (FLARE-S) confers resistance to both spectinomycin and streptomycin.

24 The resistance to the selection agent spectinomycin and to 5-methyl-Trp was transmitted matern

25 the effects of the translocation inhibitors spectinomycin and viomycin on the process.

26 of host cells to the antibiotics kanamycin, spectinomycin, and nourseothricin.

27 ies surviving on different concentrations of spectinomycin as well as the levels of transcriptional a

28 dium (MBM), which contains cycloheximide and spectinomycin at final concentrations of 0.5 mg/ml and 1

29 A comparison between the traditional spectinomycin-based aadA selection system and the ipt se

30 After identification of strains having the spectinomycin cassette inserted by a double-crossover ev

31 Spectinamides are new semi-synthetic spectinomycin derivatives with potent anti-tubercular ac

32 oramphenicol, erythromycin, fusidic acid and spectinomycin, do not induce the conformational changes

33 Tetracycline and spectinomycin have specific effects detected by this ass

34 ransformation events per bombarded sample in spectinomycin-hypersensitive Slavice and Columbia acc2 k

35 Aminoglycoside-3''-adenylytransferase, the spectinomycin inactivating enzyme, is translationally fu

36 Although the classical antibiotic spectinomycin is a potent bacterial protein synthesis in

37 cloacae (conferring resistance to kanamycin, spectinomycin, lincomycin, and gentamycin/sisomycin, res

38 mbinase action at the loxP sites excised the spectinomycin marker, leaving a single loxP site within

39 were identified as green cell clusters on a spectinomycin medium.

40 (kanamycin, gentamycin, sisomycin, amikacin, spectinomycin, neomycin), macrolides-lincosamids (erythr

41 after protein synthesis had been blocked by spectinomycin or chloramphenicol.

42 e cytosol or periplasm (e.g., ciprofloxacin, spectinomycin, or penicillin).

43 Spectinomycin reduces the frequency of the cross-link C9

44 to ceftriaxone, cefixime, azithromycin, and spectinomycin remained rare.

45 s leaves with a vector carrying a selectable spectinomycin resistance (aadA) gene and gfp, encoding t

46 e that confers a golden leaf phenotype and a spectinomycin resistance (aadA) gene that is necessary f

47 tid genome with the pCK2 vector in which the spectinomycin resistance (aadA) marker gene is flanked w

48 The pSS24 vector carries a c-Myc tagged spectinomycin resistance (aadA) marker gene whereas in v

49 The transplastomic father lines carried a spectinomycin resistance (aadA) transgene incorporated i

50 Transgenic lines were selected by spectinomycin resistance and distinguished from spontane

51 Regenerated plants are homoplasmic for the spectinomycin resistance and the Pst I markers and heter

52 hat transplastomic clones can be selected by spectinomycin resistance and visually identified by fluo

53 ng attP vectors with kanamycin resistance or spectinomycin resistance as the selective marker.

54 For this purpose, a spectinomycin resistance cassette flanked by bacteriopha

55 new nonpolar mutagenesis method employing a spectinomycin resistance cassette was used to inactivate

56 four clinical isolates were disrupted with a spectinomycin resistance cassette, and the binding of is

57 the oxidase was disrupted by insertion of a spectinomycin resistance cassette.

58 in the N. tabacum nucleus was combined with spectinomycin resistance encoded in N. sylvestris plasti

59 ings with paternal plastids were selected by spectinomycin resistance encoded in the paternal plastid

60 lied on a single selectable marker gene, the spectinomycin resistance gene aadA.

61 milar numbers of transplastomic lines as the spectinomycin resistance gene aadA.

62 The 1.7-kb gene cassette contained spectinomycin resistance gene aadA5 and trimethoprim res

63 tern blot analysis that insertion of a polar spectinomycin resistance gene in cheAY results in loss o

64 at of the GCN4 half-site in vivo, leading to spectinomycin resistance in the transcription interferen

65 and then cotransformed into IL along with a spectinomycin resistance marker (16S rrn).

66 d by direct selection for the transplastomic spectinomycin resistance marker in tissue culture; there

67 ants (>10,000/microgram of DNA) than did the spectinomycin resistance marker.

68 In the 16S rRNA-encoding DNA (rDNA) a spectinomycin resistance mutation is flanked on the 5' s

69 le RLD-Spc1 plant carrying a plastid-encoded spectinomycin resistance mutation.

70 on of PSII, an aadA gene cassette conferring spectinomycin resistance was employed for mutagenesis.

71 nce of the eubacterial aadA gene (conferring spectinomycin resistance) fused to the 5' and 3' untrans

72 ssion of a eubacterial aadA gene, conferring spectinomycin resistance, is transcriptionally suppresse

73 athway and a selectable marker gene encoding spectinomycin resistance, was flanked at the 5' end by t

74 ng gene products despite the presence of the spectinomycin-resistance cassette, which was used to ina

75 and the N-terminal half, which contains the spectinomycin-resistance mutations, directly interacts w

76 We also found that the spectinomycin-resistance phenotype was unstable in about

77 st of natA and all of natB was replaced by a spectinomycin-resistance-gene cassette exhibited phenoty

78 nalysis of co-transformants selected using a spectinomycin-resistant 16S gene (16S(spec)) provided ev

79 veloped a cotransformation approach in which spectinomycin-resistant 16S rRNA-encoding DNA is the sel

80 Spectinomycin-resistant clones were identified as green

81 In vivo spectinomycin-resistant growth rates and in vitro aminog

82 Spectinomycin-resistant transformants isolated by direct

83 '- and 9-hydroxyl groups of streptomycin and spectinomycin, respectively.

84 imized construct into tobacco and subsequent spectinomycin selection of transgenic plants yielded T0

85 When germinated in the absence of spectinomycin selection, leaf extracts from T(2) generat

86 and viomycin inhibit INT formation, whereas spectinomycin selectively inhibits INT disappearance.

87 ss was a nuclear male sterile (ms1-1/ms1-1), spectinomycin-sensitive Ler plant.

88 imparts resistance to kasugamycin (Ksm) and spectinomycin (Spc) and causes loss of one HpaI restrict

89 antibiotic binding, demonstrating a class of spectinomycin-specific functional molecular decoys built

90 ted with four-drug resistance (streptomycin, spectinomycin, sulfisoxazole, and tetracycline [St Spc S

91 acid as well as resistance to tetracycline, spectinomycin, sulfonamides, chloramphenicol, and gentam

92 For spectinomycin, the apparent binding site and the affecte

93 ent of urease activity upon adding Ni(2+) to spectinomycin-treated Escherichia coli cells that expres

94 Spectinomycin-treatment of wild-type plants phenocopies

95 emcomitans SUNY 465 transiently resistant to spectinomycin was used with conjugation to generate an i

96 G-novobiocin, pirlimycin, premafloxacin, and spectinomycin, which are used in veterinary practice.

97 he antibiotics paromomycin, streptomycin and spectinomycin, which interfere with decoding and translo

98 The reported synergism of the precursor spectinomycin with other antibiotics prompted us to exam