1 aberrant Wnt signaling activation have been
speculated.
2 Finally, we will
speculate about anaphylaxis from an evolutionary perspec
3 asthma (EIBwA ) occurring in athletes led to
speculate about different endotypes inducing respiratory
4 timal level leads to low-value screening and
speculate about pressures that encourage overly intensiv
5 Finally, we
speculate about the future of this field.
6 nal data in light of these gating models and
speculate about their mechanistic consequences on ion pe
7 We
speculate an altered lung microbiome in HIV infection ma
8 e allele is fixed or near fixation, which we
speculate are likely to be important for attenuation.
9 rams through modulation of the epigenome and
speculate as to how this may influence context-specific
10 tify trends in model development and use and
speculate as to the future use of models in infectious d
11 o use coherence-exploiting materials, and we
speculate as to the prospects for a coherent energy conv
12 texts in which these giant flagellins occur,
speculate as to their functions, and highlight the poten
13 This observation led us to
speculate as to whether our data may form the basis for
14 Finally, we
speculate as to why retrieval circuits change with time,
15 plex has long remained elusive, but has been
speculated as having infinite chains of iodine.
16 nd differences between kinase functions, and
speculates as to why mammalian germ cells require expres
17 only be to ratchet upward: Newly observed or
speculated attack capabilities can argue a countermeasur
18 The authors
speculate based on these data that sedation with inhalat
19 ory role of lipid interactions could only be
speculated from the snapshot provided by the crystal str
20 Finally, we
speculate how further studies of sequence-specific sensi
21 We
speculate how the activity we observe is consistent with
22 hinery and interferon-regulated GTPases, and
speculate how these pathways engage each other to balanc
23 onents of the oocyte cytoplasmic lattice and
speculate how this interaction could preserve ERV/host c
24 es extractable from bone matrix, it has been
speculated how targeting of BMPs to the extracellular ma
25 not variable antigens as has been so widely
speculated;
however, they do clearly play important role
26 vement between parenchyma and SCS in what we
speculate is a program of immune surveillance that helps
27 PL becomes inhomogeneous below 75K, which we
speculate is caused by the formation and subsequent dyna
28 ith unique viscoelastic properties, which we
speculate may play a key role in generating heterogeneou
29 This gain, we
speculate,
might derive from the ability of the mutant p
30 d from the border of magnetism has long been
speculated,
no experimental confirmation has been made.
31 We also
speculate on future directions in this field.
32 dies within the domain of emotions, and then
speculate on how genomic and epigenetic mechanisms can m
33 Finally, we
speculate on how technological advances will revolutioni
34 ozoal pathogen-microbiome interaction and to
speculate on how that might be leveraged for treatment.
35 ntext of immunity to influenza infection and
speculate on how the simultaneous evolutionary races of
36 -induced intestinal mucositis, and GVHD, and
speculate on possibilities of therapeutically targeting
37 s could be regulated by neuronal signals and
speculate on possible mechanisms for such regulation.
38 Finally, we
speculate on preventive and therapeutic strategies that
39 We also discuss current limitations and
speculate on the developments that are necessary to adva
40 Finally, we
speculate on the functional significance of these divers
41 We
speculate on the neural mechanisms that link sampling of
42 perspectives, highlight new discoveries, and
speculate on the opportunity created by merging the rese
43 We also
speculate on the possibility of a third level, reporting
44 We
speculate on the possible role that FSA may play in the
45 We also
speculate on the potential role of NETs in the pathogene
46 We
speculate on the relationship between the two systems an
47 With reference to the capsid structure, we
speculate on the roles of these residues in capsid stabi
48 We
speculate on the various mechanisms by which this may be
49 erature that illustrate these principles and
speculate on their implications for further study.
50 s distinguishable by regulatory proteins and
speculate on their possible consequences.
51 of electrostatics to CH-pi interactions and
speculate on what our observations imply about the absol
52 Previous work has
speculated on the phenomenological similarities between
53 is unexpected, O-linked ADP-ribosylation are
speculated on.
54 es in stress-related depression behavior and
speculates on how currently understood mechanisms contri
55 thetic chromosome construction in plants and
speculates on how they might be applied to various uses
56 ociated with survivin-targeted therapies and
speculating on the future strategies to surmount these i
57 ered role for AFPs may help explain the long-
speculated role of AFPs in freeze-tolerant species.
58 We
speculate such up-regulations may represent the early st
59 bsequently trigger chemotaxis have long been
speculated,
such a chemoreceptor has not been demonstrat
60 Sjogren syndrome, where it is interesting to
speculate that a disruption in ER redox-signaling (due t
61 We
speculate that a flexible loop linking strands beta4 and
62 Thus, one may
speculate that a GAL3 antagonist could have antidepressa
63 We
speculate that a short circadian period was advantageous
64 We
speculate that a similar cognitive architecture may unde
65 rA polymerization and gradient formation and
speculate that a transient, dynamic network of intersect
66 We
speculate that accumulation of alternatively activated m
67 s of circuit formation in the cerebellum and
speculate that adaptive reprogramming of progenitors in
68 We
speculate that adenosine modulation may provide a mechan
69 Overall, we
speculate that ADH-41 directs Abeta into off-pathway str
70 We
speculate that adhesion/excitability nodes are key sites
71 We
speculate that Al8 may form in natural water systems thr
72 We
speculate that animals that can survive extremes may be
73 Thus, we
speculate that AP2 has evolved as a key regulatory node
74 We
speculate that As adsorption to Fe in periphyton may pla
75 bats in the final stages of prey pursuit and
speculate that beam broadening is a feature characterizi
76 We
speculate that biased nucleosome and hexasome sliding du
77 In particular, we
speculate that body image may be an intervening variable
78 Furthermore, we
speculate that both the alteration in OT delivery and OT
79 Thus, we
speculate that CDKL5 deficiency disrupts activity-depend
80 is of their chromatin occupancy profiles, we
speculate that Cg limits Eya-So activation of select tar
81 muscle proliferation and differentiation, we
speculate that changes in lncRNAs might contribute to th
82 We
speculate that Chd1 senses the sequence-dependent respon
83 We
speculate that chromosomal inter-chain interactions form
84 We
speculate that cilia gene mutations contribute to both s
85 complex disorder is unclear, leading many to
speculate that concurrent delirium, psychiatric disease,
86 a in W1282X cells from one human subject, we
speculate that corrector and potentiator combinations ma
87 tion to sparse neuronal lesions leads one to
speculate that corticobasal degeneration may begin as an
88 We
speculate that cytotoxic dengue-specific CD4(+) T cells
89 We
speculate that differences in microtubule orientation be
90 We
speculate that different scales of diversity could provi
91 Based on our results, we
speculate that discernible wSuz variants may associate w
92 sential for prostate differentiation, and we
speculate that disruption of such a network predisposes
93 We
speculate that distension of the MPA may play a major ro
94 We
speculate that DMDD inhibits cytokine production in the
95 by responding to only the entry side, and we
speculate that dual entry/exit sensitivity is also impor
96 t dUTPases bind the same repressor led us to
speculate that dUTPase activity may be important to the
97 We further
speculate that each SC layer may connect two nonsister c
98 We
speculate that elevated miR-874-3p expression during wea
99 We
speculate that elevator-type antiporters such as NapA, a
100 We
speculate that estrogen replacement might ameliorate dis
101 We
speculate that estrogen replacement might partially rest
102 Based on these considerations, we
speculate that eukaryotic sex likely developed as a cell
103 We
speculate that expression of different molecular weight
104 We
speculate that expression of different molecular weight
105 We
speculate that female adolescents living in high-inequal
106 terol synthesis pathway, it is intriguing to
speculate that gammaherpesviruses have evolved to usurp
107 We thus
speculate that global change will have a larger effect o
108 Rather, we
speculate that H4K20me3 plays a role in heterochromatini
109 We also
speculate that homocysteine, cysteine, or a related liga
110 Thus, we
speculate that if we induce the binding of platelets to
111 We
speculate that in our patient the functional advantage o
112 We
speculate that interbacterial antagonism mediated by LXG
113 We
speculate that intermittent tethering of claudins to act
114 We
speculate that invasions of the House Crow have been fac
115 cause dynamin is a GTPase, it is tempting to
speculate that it has a motor activity that assists the
116 lity and lower individual variances, thus we
speculate that it may indicate a better clinical efficac
117 ortant for the end resection step of HR, and
speculate that its adjacent-localization relative to DSB
118 Based on these data, it is tempting to
speculate that light-induced changes in the protein resu
119 We further
speculate that local competition between acetylation and
120 We therefore
speculate that local sterol-hemagglutinin interactions i
121 We
speculate that locust mortality increased as a result of
122 DBP or the shorter half-life of 25(OH)D3 We
speculate that low 25(OH)D in obesity is due to a greate
123 We further
speculate that marked phase heterogeneity may be a hithe
124 We
speculate that measures to reduce maternal smoking not o
125 We
speculate that microbial derangements, as indicated in o
126 We
speculate that micromolar H2O2 is created both biologica
127 udin-2 forms gated paracellular channels and
speculate that modulation of tight junction channel gati
128 We
speculate that N-terminal acetylation imposes conformati
129 We
speculate that neovascular buds may be a precursor to ne
130 y shown to bind viral adhesion receptors, we
speculate that NKp46/NCR1 may be a novel type of pattern
131 We
speculate that non-clinical factors (e.g. genetics, epig
132 We
speculate that nuclear import of the PIC may proceed con
133 We
speculate that NUSAP1 contributes to accurate chromosome
134 We
speculate that oil drops may provide a hydrophobic inter
135 We
speculate that once the initial test is passed, the mism
136 We
speculate that paracellular permeability may have evolve
137 Thus, we
speculate that Pep2.5 may be able to prevent down-regula
138 We
speculate that phase V may be the precursor to the non-m
139 We
speculate that platelet integrins are mechanosensors tha
140 We
speculate that polymerization reactions may be occurring
141 We
speculate that pools of transfer RNA available for prote
142 We
speculate that proteolytic fragmentation may represent a
143 We
speculate that reduced expression of Fgf13 impairs excit
144 nucleus in the presence of tamoxifen, and we
speculate that remodeler recruitment may be directly med
145 These findings allow us to
speculate that retrograde signaling might involve GUN1-d
146 ein folding is largely unexplored, one might
speculate that reversed native protein sequences should
147 yotic d-ribulokinase remains unclear, but we
speculate that S. cerevisiae Ydr109c and human FGGY coul
148 rs are key players in human reproduction, we
speculate that schistosome estrogen-like molecules may c
149 It is now tempting to
speculate that similar 'many-but-one' lineage repressors
150 We
speculate that similar control of dsRNA movement could m
151 We
speculate that SMG-1 kinase activity could be activated
152 In light of this, one can
speculate that some of the GC-mediated side effects can
153 cells in vitro and DC migration in vivo, we
speculate that SP-D may constitutively stimulate IFN-gam
154 We
speculate that SQRD-1 activity in H2S may coordinate pro
155 We
speculate that SUN1/SUN2 may function redundantly in ear
156 We
speculate that surface-exposed PS directs the protease t
157 I
speculate that sustained up-regulation and/or acute acti
158 We
speculate that telomeric aggregates and ongoing breakage
159 We therefore
speculate that temperature drives Aqy1 from a loosely- t
160 Specifically, we
speculate that the "epigenetic landscapes" that define i
161 tumor suppressor proteins in cancer, and we
speculate that the additional loss of function of MOAP-1
162 We
speculate that the allosteric regulation of FVIIa activi
163 lure in translation has led investigators to
speculate that the animal models being used do not predi
164 We
speculate that the association with non-specific DNA aff
165 We
speculate that the consequent increase in distal arteria
166 We
speculate that the D145E mutation destabilises the nativ
167 We
speculate that the directionality of pI's intermolecular
168 We
speculate that the distinctive structural difference in
169 We
speculate that the early airway microbiome may prime the
170 We
speculate that the energy transported by that undulation
171 We
speculate that the frequency of p-ClPh is traced back to
172 We
speculate that the genotype-specific differences may res
173 We
speculate that the greater plasticity in silicon uptake
174 We
speculate that the interferon-induced Mx proteins might
175 We further
speculate that the intrinsic dynamics of thalamocortical
176 We
speculate that the mechanism of the mutation underlying
177 We
speculate that the minimal kinetochore configuration, wh
178 We
speculate that the negative habenula responses we observ
179 We
speculate that the newly identified CatSperzeta subunit
180 We
speculate that the observed impact of salt bridges on th
181 We
speculate that the observed maximum in the lac expressio
182 We
speculate that the potential for severe group disruption
183 We
speculate that the preferential spatial localization of
184 We
speculate that the pressures that drive the acquisition
185 We
speculate that the Rcf1/Hig1 proteins play a role in the
186 We
speculate that the repeated evolution of testis specific
187 We
speculate that the resulting farnesyl protrusion toward
188 We
speculate that the right-sided predominance reflects asy
189 We
speculate that the selective pressure imposed by competi
190 We
speculate that the specialized nature of germline chroma
191 We
speculate that the striking difference in compulsive-lik
192 We
speculate that the strong tendency to high-angle grain b
193 We
speculate that the structural change in subunit a upon r
194 We
speculate that the superfamily active-site architecture
195 We
speculate that the unusual sensitivity of skeletal muscl
196 We
speculate that the weak motifs enable processivity throu
197 hly achieving young vocal artists, one might
speculate that there is a relationship between the abili
198 Thus, we
speculate that there might be two peaks of microglial ac
199 We
speculate that these changes may be explained by an incr
200 We
speculate that these declines indicate a priming effect,
201 We
speculate that these foraminifera were transported inlan
202 We
speculate that these functional classes map onto canonic
203 We
speculate that these incumbent cells are conditioned or
204 We
speculate that these mechanisms may play a maladaptive r
205 We
speculate that these properties are optimized to meet th
206 We
speculate that they serve as channels for the genome rel
207 We
speculate that this "non-selective" form of mitophagy ma
208 trate that GPVI is a receptor for fibrin and
speculate that this contributes to development of an occ
209 We
speculate that this differential property reflects islan
210 r the first time in S. aureus, leading us to
speculate that this dinucleotide may have a regulatory r
211 We
speculate that this heterogeneity may reflect a relaxati
212 atively regulate EB1:MT interactions, and we
speculate that this interaction may assist cells in diff
213 We
speculate that this interplay between peptide structure
214 We
speculate that this interruption is due to a predominanc
215 iously assigned to OsMAS/SDR110C-MS1, and we
speculate that this latter SDR may have an alternative f
216 We also
speculate that this mechanism helps segregate tubular an
217 We
speculate that this might relate to the introduction of
218 pts normally repressed in Treg cells, and we
speculate that this network-level bias may account for N
219 Therefore, we
speculate that this new family of Ras/Rap1-specific endo
220 We
speculate that this plasticity could be maintained beyon
221 We
speculate that this protein splicing activity arose to p
222 nger pediatric intensive care unit stays, we
speculate that this SNP results in hyperinflammation in
223 We
speculate that this stiffening reflects the development
224 We
speculate that UV sensitivity conferred by these isoform
225 We
speculate that, as in sensory processing, optimization o
226 Finally, we
speculate that, if repurposed for the problem of neural
227 We
speculate that, in the shark, the differential activatio
228 Thus, it can be
speculated that a failure of dopamine receptor and trans
229 For ADEM, it is
speculated that a preceding infection is the trigger of
230 se C1q is produced by monocytes, it has been
speculated that allogeneic hematopoietic stem cell trans
231 activation) is typically observed in IRI, we
speculated that aPC ameliorates IRI by inhibiting inflam
232 We
speculated that binding of lymphoma BCRs to self-antigen
233 On this background, we
speculated that blockade of Na/K-ATPase-induced ROS ampl
234 is identical to miR-16-2; thus, it could be
speculated that both clusters control a similar set of t
235 Researchers have
speculated that clonidine limits the amount of mental se
236 We
speculated that CN(-) and the CO precursor (-):CO2H may
237 ch depends on transcription, and it has been
speculated that cohesin movements along DNA could create
238 g the Last Glacial Maximum (LGM) it has been
speculated that endemic species of soil invertebrates co
239 It is
speculated that Fe3O4 nanoparticles accumulated in the c
240 nctional horizontal gene transfer (fHGT) and
speculated that fHGT was likely formative in the evoluti
241 It is
speculated that genetic variants are associated with dif
242 sk factor for the development of BM, thus we
speculated that higher circulating estrogens in young, p
243 We
speculated that hyperglycemia inhibits skin DC migration
244 It is
speculated that immunoglobulin G (IgG) plays a regulator
245 We
speculated that low-frequency oscillations observed in t
246 It has been
speculated that LVAD support itself may cause angiodyspl
247 derlying this process remain unknown, it was
speculated that mediators released from platelet granule
248 Only very recently it was
speculated that metal cations could also play an importa
249 It has been
speculated that microtubules can serve as tracks to deli
250 Plant biologists have long
speculated that outcrossing mating systems are more comm
251 It has been
speculated that PAI-1 may regulate cardiac fibrosis by i
252 Although it has been
speculated that proteasome dysfunction may contribute to
253 Therefore, it has been
speculated that pyruvate oxidation through PDH is decrea
254 plex OM is often a polymicrobial disease, we
speculated that reduction of complex OM by PCVs would be
255 thors reporting this methodical breakthrough
speculated that SCNT would allow the creation of patient
256 We
speculated that serum pantetheinase might contribute to
257 It had been
speculated that sIL-6R was generated at the site of infl
258 Although it has been
speculated that stem cell depletion plays a role in the
259 From this, it can be
speculated that tetrapyrroles attached to phycobiliprote
260 Many researchers have
speculated that the clinical progression from monoclonal
261 While it has long been
speculated that the cyclohexene moiety found in many sec
262 We therefore
speculated that the dissociation requires a conformation
263 rns relative to full-term infants, and it is
speculated that the hospital room environment may contri
264 Thus, it can be
speculated that the latter pathway might be beneficial t
265 It has been
speculated that the mechanism by which thick filament le
266 lasticity in other hippocampal subfields, we
speculated that the metabotropic glutamate receptor mGlu
267 -(1-->3)-alpha-d-GlcNAc-(1-->OPO3-->]n ), we
speculated that the two predicted CPs (CslA and CslB) wo
268 reports in some scientific and public media
speculated that the virus had evolved to more effectivel
269 It has been
speculated that these early enzymes had low specificitie
270 nes during dedifferentiation of PHHs, and we
speculated that these modulations could drive the hepati
271 rent gross structural chromosomal damage, we
speculated that they may arise from chromothripsis, a re
272 Furthermore, it may be
speculated that this pair of side chains could promote o
273 We
speculated that this plays important roles in the struct
274 r stage development of malaria parasites and
speculated that TMP-SMX prophylaxis during repeated mala
275 On the basis of in vitro studies, it was
speculated that transferrin can bind Ti(IV) assisted by
276 It has long been
speculated that Varroa via immunosuppression of the bees
277 We
speculated that: (i) young children could respond random
278 t-term effect on HPV-associated disease; and
speculates that even a single dose of these vaccines, wh
279 We can only
speculate the reasons for many of these results at this
280 We can only
speculate the reasons for many of these results at this
281 We
speculate these are potential mechanisms by which nAChR
282 tal variability are ubiquitous in nature, we
speculate this evolutionary mode to be of general releva
283 ve disorders to muscular dystrophy, which we
speculate to be consistent with oligogenic mechanisms re
284 Cellular lipids are
speculated to act as key intermediates in Hedgehog signa
285 c disorders is unknown, although it has been
speculated to be a combination of environmental, stress
286 Collagen was
speculated to be an allergen in this study.
287 reviously studied by electron microscopy and
speculated to be for cuticle formation.
288 on mechanism of these submesoscale eddies is
speculated to be related to the horizontal velocity shea
289 on by the photoactive layer itself, has been
speculated to contribute to the high open-circuit voltag
290 This phenomenon is
speculated to correlate with the rotational effects of p
291 tissues and organs over time, and have been
speculated to have a role in ageing.
292 Although calcium-enriched diets have been
speculated to increase prostate cancer risk, their impac
293 in which an increased lipid signal has been
speculated to indicate neoatherosclerosis, and NIRS find
294 The mechanism for this process is
speculated to involve dynamics of solvent cluster format
295 scopal effect, but historically, it has been
speculated to reflect the generation of a host immunothe
296 Although they are
speculated to regulate gene expression in developmental
297 nitiation of explosions, which has long been
speculated to result from 'hot spot' generation at local
298 Although infections are
speculated to trigger the syndrome, a specific infectiou
299 tant case is molybdenum, which has long been
speculated to undergo an exceptionally steep increase in
300 We therefore
speculated whether increased expression of EBI2 would le