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1 is unexpected, O-linked ADP-ribosylation are speculated on.
2 landscape for neuronal calcium sensor-1 and speculate on a direct link between protein misfolding an
5 background in certain mtDNA-based diseases, speculates on a pathogenic role for a subset of LHON sec
14 eed to have narrow ion-selective filters, we speculate on how an exchanger might evolve to show chann
17 ies that go beyond cognitive subtraction and speculate on how functional imaging can be used to addre
18 of ongoing trials and their limitations, and speculate on how future trials could be made more effici
19 dies within the domain of emotions, and then speculate on how genomic and epigenetic mechanisms can m
21 etic retinopathy, its relative safety and we speculate on how it could be developed for intraocular d
24 ntal features of these two approaches and to speculate on how proteomics will be useful in nephrology
25 and draw on various experimental findings to speculate on how remyelinating therapies are likely to d
27 system, a paradigm for efflux machinery, and speculate on how RND pumps assemble to fight diverse ant
28 g the affinity of weak interactions and also speculate on how SIRPalpha polymorphisms may have been s
30 ozoal pathogen-microbiome interaction and to speculate on how that might be leveraged for treatment.
32 transmitter may drive synapse formation, and speculate on how the environment of the developing brain
33 ntext of immunity to influenza infection and speculate on how the simultaneous evolutionary races of
34 n about the function of calcium channels, we speculate on how this missense mutation leads to the com
35 also consider the data on Ang1 receptors and speculate on how to maximize therapeutic benefit by targ
36 es in stress-related depression behavior and speculates on how currently understood mechanisms contri
37 thetic chromosome construction in plants and speculates on how they might be applied to various uses
41 istate model of transcription regulation and speculate on its role in the dynamic repression of the e
42 reatment, and outcome of this condition, and speculating on its nosological status vis-a-vis the syst
43 d to block AA and DHA oxidation, we close by speculating on likely areas of future research directed
44 present in maize provides an opportunity to speculate on mechanisms that might lead to heterosis.
47 have been shown to impinge on mTOR, we also speculate on other signal-transduction pathways that may
48 -induced intestinal mucositis, and GVHD, and speculate on possibilities of therapeutically targeting
52 s could be regulated by neuronal signals and speculate on possible mechanisms for such regulation.
54 ase apoprotein binds numerous metal ions, we speculate on possible roles for the UreD, UreF, and UreG
57 n the idiopathic inflammatory myopathies and speculates on possibly useful novel approaches for the f
58 the combined imaging/penetration results, we speculate on potential sites of cholinergic action in th
61 to their notable achievement and reflect and speculate on some of the scientific and personal nuances
62 To that end, a final section of the article speculates on specific ways that these trends are likely
63 s within a general plant biology context and speculate on the answers to some remaining questions.
64 atient with class III-IV lupus nephritis and speculate on the association between invasive Moraxella
66 n and pathogenesis of autoimmune disease and speculate on the benefit for probiotic therapies against
67 asticity in target gene selection by MYC and speculate on the biochemical and genomic contexts in whi
68 xistence of channels in transporters, and we speculate on the biological significance of this newly u
69 seased human tissues were used previously to speculate on the causes of periodontitis and to describe
70 ship of structure to biological function and speculate on the complex origin of these crucial regulat
71 r two longer wavelength cone systems, and we speculate on the consequences for color processing in th
75 zation between metalated As(CSL9C)(3) and to speculate on the differential basis of Hg(II) binding in
78 herapeutics, summarize progress to date, and speculate on the eventual utility of such agents in the
79 tion of resistance mutations, leaving one to speculate on the fate of these mutants once the antibiot
86 the predetermined mode is the release and we speculate on the importance of these two processes in te
89 utophagy in innate and adaptive immunity and speculate on the intriguing interplay between these two
94 perspectives, highlight new discoveries, and speculate on the opportunity created by merging the rese
101 venues for improving prediction accuracy and speculate on the possible use of WGP to prospectively id
102 by pathogens for their own transmission and speculate on the potential of ERM proteins for regulatin
103 perception on carpel development lead us to speculate on the potential role of light-regulated mecha
105 perfusion injury and preconditioning, and to speculate on the potential role of preconditioning in th
107 idence for NsrR as a global regulator and to speculate on the recent controversy over its NO sensing
108 stence and function of the interactions, and speculate on the regulatory roles that such long-distanc
114 s and the mechanisms of redox signaling, and speculate on the role that mitochondrial anisotropies mi
116 up to the final product formation step, and speculate on the roles of the enzymes in the lifecycle o
117 With reference to the capsid structure, we speculate on the roles of these residues in capsid stabi
118 the associated conceptual advancements, and speculate on the shape novel theories of the cortex may
124 body perception from birth [13], others have speculated on the importance of postnatal experience [14
125 civic centre of Knossos, archaeologists have speculated on the origin of the founders of the civiliza
127 st the 16th century, many investigators have speculated on the presence of a specialized muscle in th
129 henotyping" of electronic health records and speculates on the impact such computational capabilities
130 technologies are highlighted and the author speculates on the importance of biosensors as a ubiquito
131 motifs that have been identified so far and speculates on the importance of their role in determinin
132 link between circadian clock and cancer, and speculates on the possible connections at the epigenetic
133 he animal and early clinical experience, and speculates on the potential of genetic manipulation of b
136 he different methods and their findings, and speculates on the value of combining these techniques to
137 ociated with survivin-targeted therapies and speculating on the future strategies to surmount these i
142 review viral mechanisms to regulate the APC, speculate on their roles during infection, and identify
143 l and ecological features of charophytes, we speculated on their possible use as biomonitors and bior
144 al roles of small RNAs in immune biology and speculates on their potential participation in lymphogen
147 uclear localization signal (NLSI) in p53 and speculated on two additional sites termed NLSII and NLSI
149 of electrostatics to CH-pi interactions and speculate on what our observations imply about the absol
150 studied eukaryotic Pif1 family helicases and speculate on what roles such enzymes may play in bacteri
151 perimental evolution have told us so far and speculate on where progress might be made in the future.
155 d discuss their functional significance, and speculate on why this situation might have evolved.
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