ライフサイエンスコーパス: speculation

1 mportant aspects of ancient exchange open to speculation.

2 ERK signal transduction is still a matter of speculation.

3 y bowel disease (IBD) is the subject of much speculation.

4 s in most species, has long been a matter of speculation.

5 arbon on Mars have been a subject of intense speculation.

6 oducing enzyme system(s) remains a matter of speculation.

7 tient care and hospital costs is a matter of speculation.

8 to be put to rest with solid science and not speculation.

9 eta to memory remains the subject of intense speculation.

10 ringia has long been subject to research and speculation.

11 rons have been the subject of much study and speculation.

12 lls in these species has remained a topic of speculation.

13 effect has remained elusive and a subject of speculation.

14 g areas of current interest, contention, and speculation.

15 al decay in aging humans remains a matter of speculation.

16 ecificity in malarial ADAs is the subject of speculation.

17 ein molecular docking studies supported this speculation.

18 biotic biosynthesis has been subject to much speculation.

19 understood, despite much experimentation and speculation.

20 eptions has been the subject of considerable speculation.

21 rning RuBisCO evolution have been limited to speculation.

22 le data, not good intention, assumptions, or speculation.

23 insulin receptor has long been a subject of speculation.

24 cific cellular source of iNOS is a matter of speculation.

25 of their goals has been the subject of much speculation.

26 ry bypass grafting (CABG) are the subject of speculation.

27 e 6-hydroxyl groups, has been the subject of speculation.

28 has therefore been the subject of particular speculation.

29 nd behavior has been the subject of numerous speculations.

30 elated stimuli are seeking to validate these speculations.

31 Although speculation abounds regarding ongoing decay and looming

32 ent in all three domains of life, leading to speculation about a common viral ancestor that predates

33 at little is known has prompted much hopeful speculation about a generalized mechanistic thread that

34 male sex in humans and other mammals led to speculation about a possible equivalent for female sex.

35 Decades of speculation about a warmer, wetter Mars climate in the p

36 Speculation about an Iraq war syndrome has already start

37 osperms forms the mechanistic foundation for speculation about how angiosperms drove sweeping ecologi

38 We end our commentary by offering some speculation about how Pessoa's arguments naturally exten

39 Speculation about how to successfully resolve these issu

40 is highest in lung, and there has long been speculation about its precise role, due to the dual requ

41 and form the main thrust of this paper, with speculation about other disciplines and emphasis that al

42 regulated cell death in bacteria have led to speculation about possible benefits that apoptosis-like

43 Hence, our data help to resolve speculation about the "apparent" loss of this fraction f

44 image the human brain have provoked excited speculation about the application of neuroscience to oth

45 the location of functional receptors, allows speculation about the circuits that make use of these re

46 t following TCD transplantations and invites speculation about the function of DPB1 within the immune

47 There has been considerable speculation about the function of interstitial cells of

48 There has been much speculation about the functional role of Src in colorect

49 These data and recent speculation about the importance of arginine in biofilm

50 lying ssRNA-capsid co-assembly, and inspires speculation about the links between nucleoprotein comple

51 only fragments of these complexes, inspiring speculation about the overall protein assembly and confo

52 within heteroplasmic individuals has led to speculation about the potential for independent evolutio

53 changes associated with its binding, provoke speculation about the regulatory role of the auxiliary s

54 cture of these modular proteins has fostered speculation about the roles of these novel molecules in

55 Speculation about the source of contamination has been w

56 Increasing speculation about the use of histone deacetylase (HDAC)

57 There has been much speculation about their age, but progress in dating cact

58 ession of most targeted proteins, leading to speculation about their role in the variability, or nois

59 976 as periodic recertification emerged, and speculation about what certification might look like in

60 poral requirements for SMN in mice, renewing speculation about when and where repletion of SMN is nec

61 from Hungary in 1242 CE, has generated much speculation and an array of controversial theories.

62 th its size and duration, and there has been speculation and concern regarding the potential for EBOV

63 These findings culminate 50 years of speculation and debate concerning the chlamydial anomaly

64 ession changes--has long been the subject of speculation and debate.

65 inant causes of price increases are investor speculation and ethanol conversion.

66 onary and developmental biologists, yielding speculation and hypotheses concerning their putative hom

67 follow a similar pattern of experimentation, speculation and marginalization.

68 re of eukaryotic cells, was long shrouded in speculation and mystery.

69 sorting out reliably established facts from speculations and unsubstantiated claims.

70 croRNA clusters has been the subject of much speculation, and a selective advantage of clusters of fu

71 as been the subject of investigative effort, speculation, and controversy.

72 implicated this region in dyslexia and some speculations are made in this regard.

73 These intriguing findings provoke speculation as to how a cell decides to undergo either a

74 Although there has been some speculation as to possible links between diabetes and Al

75 wn to have more than 100 CPR genes, inviting speculation as to the functional importance of this larg

76 of its geographical localization and allows speculation as to the worldwide spread of the virus, ver

77 This has generated interest and speculation as to their function during infection.

78 There has been much speculation as to what role balancing selection has play

79 blastoma cell line to facilitate preliminary speculation as to where highly malignant tumours might f

80 riguing observation only adds to the current speculation as to whether or not MOFs may find a role as

81 It remains a matter of speculation as to whether the sense CUG-containing RNA a

82 Though there are many speculations as to its function, based solely on sequenc

83 tudied over the past few decades, leading to speculations as to the mechanism by which stripes, spots

84 he defects caused by aneuploidy and end with speculations as to whether and how aneuploidy, despite i

85 s, which indicates that contrary to previous speculations, ASPM and MCPH1 have not been selected for

86 lculations and corroborate the long-standing speculation based on theoretical calculations in previou

87 Current interpretation of indirect data and speculations based on theoretical considerations are inc

88 value of STEM education involve substantial speculation because they ignore the impacts of economic

89 nsal rodents are the subject of interest and speculation but accurate data are rarely available.

90 , which is a subject that has attracted much speculation but little scholarship.

91 ism of its biosynthesis invited much initial speculation but was finally clarified by the discovery o

92 on zoonotic disease risk are the subject of speculation, but lack a coherent framework for understan

93 bre axons have made them the subject of much speculation, but little experimental progress for the pa

94 imprinting changes, there has been extensive speculation, but no robust evidence, that imprinted gene

95 Fitness landscapes are the subject of much speculation, but their structure is essentially unknown.

96 ions have long been a source of interest and speculation, but there is very little structural informa

97 ith global warming has long been a topic for speculation, but was never addressed using a climate mod

98 Thus, contrary to earlier speculation, C5l2 is a functional receptor rather than m

99 Speculation can produce many plausible scenarios, but ou

100 amate transporter, VGLUT3, has brought about speculation concerning its role and function based on it

101 Speculation concerning the influence of metabolic rate o

102 Speculation concerning the neurobiobehavioral substrates

103 There is considerable speculation concerning the role of the ubiquitous antiph

104 sks and systems has prompted an expansion of speculations concerning the function of the cerebellum.

105 ng with phenomena such as rhetorical intent, speculations, contradictions and negations.

106 haracterizes a process known as neoteny, and speculation exists over whether it has contributed to th

107 spite an obvious link to a petroleum source, speculation exists that biogenic sources also contribute

108 otent progestin in the horse ends decades of speculation, explaining how equine pregnancies survive w

109 ted in these mammals has been the subject of speculation for decades.

110 dot (QDs) alloys has been an area of active speculation for over a decade.

111 e stability after cervical hemisection raise speculation for potentially diverse roles in modulating

112 Here, we examine such speculation from the perspective of the functional prope

113 This speculation has been based on observations of similar ac

114 Speculation has long revolved around whether more primit

115 Speculations have been made that the wrack accumulating

116 a systematic investigation of such enticing speculations impossible.

117 ntly a subject of much research interest and speculation in terms of host health.

118 There has been some speculation in the literature that formation may occur f

119 val of 3mA from DNA is currently a matter of speculation, in part owing to the lack of a structure of

120 If this speculation is correct, then one should see more O(2)(*)

121 ce on the brain are largely unknown, and any speculation is inferred from heroin and methadone studie

122 Speculation is offered on potential strategies and solut

123 One speculation is that neurons in motor cortex reflect this

124 and DNA synthesis is not known, but a simple speculation is that phi base pairs with the 5' half of e

125 One speculation is that the mutant Atp13a2(Isoform-1) protei

126 e of FET3 repression by Izh2p is a matter of speculation, it provides a reporter with which to probe

127 well established; and although an appealing speculation, its role in fostering the evolution of MGUS

128 of which are current targets of considerable speculation, may be nothing more than indirect by-produc

129 Despite much speculation, no direct evidence has been presented to re

130 here (SH) field morphology and has motivated speculation of an impending reversal.

131 rs orbit showed localized patches, prompting speculation of sources from subsurface bacteria or nonbi

132 pinosyn biosynthetic gene cluster led to the speculation of spnJ as the possible oxidase gene.

133 This has prompted speculation of what their influence would be on habitabi

134 al ice reductions in the future, have fueled speculations of potential new trans-Arctic shipping rout

135 o ethanol in the United States, and investor speculation on commodity markets lead to widely differin

136 pleiotropy of the Notch pathway can confound speculation on possible segmentation mechanisms in the l

137 We also review recent speculation on the evolution and adaptive value of white

138 This finding invites speculation on the future role of metabolic imaging for

139 improve discussion sections by shifting from speculation on the impact of sources of error to quantif

140 s in the immune response and provide further speculation on the putative mechanisms by which LAP may

141 presented based on these findings, allowing speculation on the putative role of Nin88 in muro.

142 artemisinin tolerance/resistance has led to speculation on their continued long-term effectiveness.

143 iable between individual synapses, prompting speculation on their specific relationship, and on the p

144 derstanding of how anti-VEGF agents work and speculation on when to implement them clinically for neo

145 We provide some speculation on why detecting GxE in a genome-wide associ

146 I conclude with speculations on further developments and a comment on th

147 This finding confirms previous speculations on the 'ventral pathway of somatosensory pe

148 These data prompted intriguing speculations on the IP/G alpha s coupling which mediates

149 okine signaling will be summarized, and some speculations on the significance and implications of the

150 Speculation over the role of screening will continue unt

151 close association with egg clutches leads to speculation over the type and extent of care exhibited b

152 There has been speculation over whether borderland cultures such as Gre

153 Much speculation persists regarding bat evolution; however, l

154 The speculation pictures calsequestrin polymers as 'wires' t

155 Speculation prompted a reisolation of spiroleucettadine

156 mmetry have been the subject of considerable speculation; proposals for the advantages associated wit

157 eir existence was initially pure theoretical speculation, recent years have seen several experimental

158 However, there has been active speculation regarding the cause of behavioural changes e

159 involved in apoptosis, leading to extensive speculation regarding the evolution of apoptosis.

160 on a double logarithmic plot has led to much speculation regarding the number and nature of the criti

161 There has been much speculation regarding the origin of this aberration in s

162 The results invite speculation regarding the potential exploitation of this

163 H(4+) 4 Cl(-) provides a starting point for speculation regarding transition-state assemblies.

164 he assumed function of these genes and offer speculation regarding which components of the arthropod

165 thways, although the subject of considerable speculation, remain unclear.

166 Optimism and speculation require a counterweight.

167 uth magnetic poles--have been the subject of speculation since the first detailed observations of mag

168 Observed speculation slows convergence by impeding the process wh

169 Despite much speculation, strong evidence of the mechanisms by which

170 h these findings are in contrast to previous speculations suggesting redox mediation of electron tran

171 Speculation that a universal varicella vaccination progr

172 This has led to speculation that A30P forms aggregates that are distinct

173 There has been speculation that adolescents with anxiety are at risk fo

174 function in cultured cell models, prompting speculation that Aire-PHD:H3-tail interactions underlie

175 These findings have resulted in speculation that alterations in the gut microbiome may p

176 ined cone structure and function support the speculation that alternative pathways are critical for c

177 rupting from Saturn's moon Enceladus fuelled speculation that an internal ocean was the source.

178 ly in the mammalian liver and brain, fueling speculation that aneuploidy provides a selective advanta

179 This has led to speculation that another subset of T cells may significa

180 This has led to speculation that antioxidants like selenium (Se) may pla

181 ndoplasmic reticulum Ca(2+) stores, fuelling speculation that archetypal intracellular Ca(2+) channel

182 udies comparing several endemic sites led to speculation that as transmission decreases morbidity and

183 ved WxxxE signature sequence, leading to the speculation that bacterial G protein mimicry may result

184 There has long been speculation that barley was domesticated more than once.

185 These two points have led to speculation that BipA may be a novel regulatory protein

186 There has been growing speculation that cephalopod populations are proliferatin

187 al variation in eczema prevalence has fueled speculation that climate may modulate disease activity.

188 Combined data lead to the speculation that CRP acts on the effector cells of the i

189 It is the authors' speculation that diabetes induces blood-vitreous barrier

190 th the endoplasmic reticulum (ER) has led to speculation that distribution of these two organelles is

191 These results also allow for the speculation that DNA damage to genes coding for electron

192 form-specific homophilic binding, leading to speculation that Dscam proteins mediate cell recognition

193 ion called 'listless.' These findings led to speculation that E(2) deprivation, under these condition

194 between heart rate and lifespan, leading to speculation that elevated heart rate could significantly

195 n vegetative tissues and confirm the earlier speculation that elevating fatty acid biosynthesis in th

196 Consequently, there has been speculation that end-of-life care in the ICU represents

197 ent vasodilatation in humans, leading to the speculation that endothelial dysfunction contributes to

198 verity and remission rates in IBD has led to speculation that eosinophils may contribute to the antim

199 that of 2OH-4MeO-BP, our results invite the speculation that exposure to elevated 2,4OH-BP levels ma

200 ates in Martian soil samples has fueled much speculation that flows of perchlorate brines might be th

201 These findings validate Gelei's speculation that full-length pairing of homologous chrom

202 umulation of GHB in ssadh mutants led to the speculation that GHB is the cause of aberrant phenotypes

203 form both homo- and heterodimers, has led to speculation that GPCR dimers may be required for efficie

204 There has also been speculation that H7N9 will have few CD4 T-cell epitopes.

205 f alpha(2) and a substrate (CDP), leading to speculation that HU might intercept a transient ET pathw

206 ction with ICU end-of-life care has prompted speculation that ICU palliative care has improved over t

207 n in brains of stimulant users have prompted speculation that increasing dopamine signaling might hel

208 of evidence for chromosome breaks has led to speculation that infecting Mu might use a cut-and-paste

209 Despite decades of speculation that inhibiting endogenous insulin degradati

210 ) dendritic cells (DCs) in vitro have led to speculation that inhibition of AXL would promote antivir

211 nd possesses a papain-like domain, prompting speculation that it functions as a proteolytic enzyme.

212 ral product found in potato tubers, there is speculation that it inhibits sprout growth by prolonging

213 than in the reduced state, which has led to speculation that it is the dynamics of the protein that

214 aternal zinc supplementation, supporting the speculation that it results from an inherited genetic co

215 I secretion system (T6SS) was met with early speculation that it too acts as a 'needle' that pathogen

216 xposed to UV light has been observed raising speculation that lens cells themselves could act as phag

217 eral experimental studies do not support the speculation that low intracranial pressure and the resul

218 The novel addition offered here is the speculation that low-abundance, gain-of-function somatic

219 brain monoamine oxidase A (MAO A) leading to speculation that MAO A inhibition by tobacco smoke may u

220 aque-substrate interface have often prompted speculation that Mefp-5 plays a key role in adhesion.

221 This model is fully consistent with our speculation that monovalent counterions play an importan

222 ts and Crohn's disease in humans have led to speculation that Mycobacterium avium paratuberculosis (M

223 s derived from infected animals prompted our speculation that neutrophils modulate the proinflammator

224 wth cone collapse, have led to a widely held speculation that NG2 cells themselves also repel and inh

225 e itself a piece of crowd wisdom, leading to speculation that online voting may soon put credentialed

226 tor involvement has been reported, prompting speculation that other mosquitoes such as Culex quinquef

227 This result allowed speculation that oxidation of Cys436 and phosphorylation

228 releasing hormone processing, leading to the speculation that PC1 subserves different functions betwe

229 erved during the Black Death has even caused speculation that plague was not the cause of this mediev

230 of buffering is qualitatively explained by a speculation that puts together ideas first proposed by o

231 induced liver injury and fibrosis, prompting speculation that Rac may be a therapeutic target in pati

232 are proposed to be highly mobile, prompting speculation that resistomes may not correlate with phylo

233 ns, providing evidence for the long-standing speculation that retrotransposable elements in mRNAs are

234 at Sgt1p interacts with Hsp90 has led to the speculation that Sgt1p and Hsp90 form a co-chaperone com

235 s, including Alzheimer's disease, leading to speculation that sIBM pathogenesis has similarities to n

236 The review ends with speculation that sigma-bond-forming reactions may also b

237 cell and hepatocellular carcinoma has led to speculation that silencing of SOCS1 and SOCS3 genes migh

238 e controversial, which has led to widespread speculation that Smo signals through a variety of novel

239 There is speculation that the additional BchH homologs may regula

240 ll the experimental observations lead to the speculation that the CBPQT((2+)(*+)) ring of the bisradi

241 elial phenotype of primary tumors has led to speculation that the disseminated tumor cells recruited

242 This has led to speculation that the domains of native VAR2CSA need to c

243 The cognitive impairments lead to speculation that the dystrophin protein family may play

244 ECC) than the general population, leading to speculation that the etiology and characteristics of the

245 rta in various vertebrate species has led to speculation that the floor of the dorsal aorta may play

246 ts have been reported, has generated further speculation that the fungus is an opportunistic pathogen

247 ed primarily by malignant B cells, prompting speculation that the genes might be induced by host-deri

248 ular signal transduction networks has led to speculation that the high degree of interconnectivity th

249 ic infiltrates of multiple organs, provoking speculation that the lymphotoxin pathway may play a role

250 cells from the ciliary epithelium has led to speculation that the mammalian retina and/or surrounding

251 located in the N terminus, which has led to speculation that the protein may be autoproteolytically

252 These observations have engendered speculation that the seemingly flexible gamma(4) residue

253 of the energy is unaccounted for, leading to speculation that the unmeasured pickup ions or energetic

254 These observations have inspired speculation that the use of common skin washing techniqu

255 xamined, ysrT is a separate gene, leading to speculation that there is a functional advantage to YsrT

256 iver, pancreas, and other tissues led to the speculation that these cells might be the source of adul

257 ion of another animal's behavior, leading to speculation that these circuits participate in sensory l

258 has yielded conflicting findings, fostering speculation that these conditions associate only in cert

259 mbrian acorn worm lived in tubes, leading to speculation that these fossils may have been pterobranch

260 These results raise speculation that these genetic factors may contribute to

261 is currently a matter of intense study amid speculation that these ncRNAs have key regulatory roles.

262 n in HepG2 cells which understandably led to speculation that these same vectors would be immediately

263 f found in numerous effectors leading to the speculation that they all function by a similar molecula

264 than 3d-block compounds, and this has led to speculation that they could be used in molecular spintro

265 been successfully cultured, which has led to speculation that they may be obligately dependent on the

266 This has led to speculation that they may dispense with the daily clock.

267 ns that tRNAs are trimmed in both, prompting speculation that they may have developed novel alternati

268 these genes in serotonergic neurons invites speculation that they may mediate an underlying disease

269 n and frequency of conical cells have led to speculation that they play a role in attracting animal p

270 irect evidence for ocean cooling has lead to speculation that this abrupt event was purely local to G

271 There is evidence and speculation that this cultural transmission of behavior

272 orm colloidal aggregates, and there has been speculation that this may affect the absorption and dist

273 oimmunity and infectious disease, as well as speculation that this mechanism may be responsible for t

274 ion factors encoded in its genome has led to speculation that this organism may be unusually reliant

275 condary vector, Aedes albopictus, leading to speculation that this was a major factor in expansion.

276 , and psychophysical experiments, has led to speculation that V1 activity has a special or direct rol

277 Indeed, there has been speculation that viral membranes form de novo in cytopla

278 e and non-Hodgkin lymphoma (NHL) have led to speculation that vitamin D may protect against lymphomag

279 rminal sterile alpha-motif (SAM), leading to speculation that Yan/TEL1 polymers may spread along chro

280 Some population genetics studies have led to speculation that, until recently, this species constitut

281 These findings have led to speculations that cohesin ring-like structures normally

282 The findings support speculations that music and language share mechanisms th

283 f PRM-S, provide an explanation for previous speculations that PRM-A may contain a second mannose bin

284 vidence of heterozygosity, supporting recent speculations that this organism is sexual.

285 Contrary to speculation, the divergent carboxyl-terminal tail domain

286 Despite considerable speculation, the evolutionary origins of this species' r

287 Despite 80 y of speculation, the origins of these developmental patterns

288 Despite decades of speculation, the proton pumping mechanism of complex I (

289 also expressed in parietal cells, leading to speculation they form a native channel complex there.

290 n the past 50 years, this idea has gone from speculation to a prevailing idea.

291 Despite early speculation to the contrary, all tropical forests studie

292 er evolutionary potential remains an area of speculation: various keys to success have been proposed

293 Prior speculation was that local composition controlled which

294 Finally, in contrast to previous speculation, we confirmed that acidification of the cult

295 ow available, rounding off the analysis with speculation where necessary.

296 d 2010/2011 are specifically due to investor speculation, whereas an underlying upward trend is due t

297 tic-resistant bacteria is a fertile area for speculation with few defined mechanisms.

298 of either cell type has long been an area of speculation with no definitive head-to-head trial.

299 There is much speculation with regard to the potential cardioprotectiv

300 Hologenomic speciation remains testable speculation without experimental support.