ライフサイエンスコーパス: spin labeling

1 ually activated region (measured by arterial spin labeling).

2 nsory cortex activity (quantitative arterial spin labeling).

3 images and to perfusion images from arterial spin labeling.

4 e thiosulfonate spin label for site-directed spin labeling.

5 erfusion decrement using continuous arterial spin labeling.

6 cosahedral protein cages using site-directed spin labeling.

7 nanosecond backbone motions by site-directed spin labeling.

8 es into calmodulin by means of site-directed spin labeling.

9 n overexpression of holo-protein followed by spin labeling.

10 ssion imaging both with and without arterial spin labeling.

11 and C2B) were determined using site-directed spin labeling.

12 hia coli, were investigated by site-directed spin labeling.

13 the Ton box was examined with site-directed spin labeling.

14 s on T4 lysozyme introduced by site-directed spin labeling.

15 seudo-continuous magnetic resonance-arterial spin labeling 20 +/- 6 hours before and after TMS treatm

16 In site-directed spin labeling, a covalently attached nitroxide probe con

17 In site-directed spin labeling, a nitroxide-containing side chain is intr

18 h the undocking of this region proposed from spin-labeling analyses.

19 Here, we use site-directed spin labeling and a novel total internal reflection fluo

20 ealthy volunteers were scanned with arterial spin labeling and a separate 15 with BOLD.

21 Arterial spin labeling and asymmetric spin echo sequences measure

22 Site-directed spin labeling and both continuous wave (CW) and pulsed E

23 We have quantified both site-directed spin labeling and dehydroalanine formation.

24 Here we report a systematic spin labeling and double electron electron resonance (DE

25 In this study, site-directed spin labeling and double electron-electron resonance spe

26 structures in a mechanistic context, we use spin labeling and double electron-electron resonance spe

27 the cytoplasmic surface using site-directed spin labeling and double electron-electron resonance spe

28 hyl-based labels, approach for site-directed spin labeling and efficient immobilization procedure tha

29 Here we used site-directed spin labeling and electron paramagnetic resonance (EPR)

30 a prokaryotic homologue, using site-directed spin labeling and electron paramagnetic resonance (EPR)

31 Here we use site-directed spin labeling and electron paramagnetic resonance (EPR)

32 previously been identified by site-directed spin labeling and electron paramagnetic resonance (EPR)

33 ding cleft of myosin, based on site-directed spin labeling and electron paramagnetic resonance (EPR)

34 the substituted domains using thiol-specific spin labeling and electron paramagnetic resonance (EPR)

35 ious compositions, and initial site-directed spin labeling and electron paramagnetic resonance (EPR)

36 In this study, site-directed spin labeling and electron paramagnetic resonance (SDSL-

37 stance restraints derived from site-directed spin labeling and electron paramagnetic resonance (SDSL-

38 Here, we used spin labeling and electron paramagnetic resonance spectr

39 Here, we use site-directed spin labeling and electron paramagnetic resonance spectr

40 We have previously used site-directed spin labeling and electron paramagnetic resonance spectr

41 Site-directed spin labeling and electron paramagnetic resonance spectr

42 (KvAP) at 0 millivolts, using site-directed spin labeling and electron paramagnetic resonance spectr

43 In this study, we used site-directed spin labeling and electron paramagnetic resonance spectr

44 We used site-directed spin labeling and electron paramagnetic resonance to ana

45 sly established the utility of site-directed spin labeling and electron paramagnetic resonance to det

46 Site-directed spin labeling and electron paramagnetic resonance were u

47 onal changes were investigated by systematic spin labeling and EPR analysis.

48 Using site-directed spin labeling and EPR distance measurement we show that

49 We have used site-directed spin labeling and EPR spectroscopy to detect structural

50 e-mediated misfolding, we used site-directed spin labeling and EPR spectroscopy to generate a three-d

51 Here we have used site-directed spin labeling and EPR spectroscopy to probe the molecula

52 Site-directed spin labeling and EPR spectroscopy were used to map two

53 changes in loop C, measured by site-directed spin labeling and EPR spectroscopy, reveal immobilizatio

54 Using site-directed spin labeling and EPR spectroscopy, we show that the ove

55 yeast, was investigated using site-directed spin labeling and EPR spectroscopy.

56 Here we developed a site-directed spin labeling and EPR-based approach for determining the

57 e assessed using voxel-based pulsed arterial spin labeling and morphometric analyses and tested for a

58 in has been characterized using paramagnetic spin labeling and NMR.

59 consistent with the results of site-directed spin labeling and places the peptide backbone in the bil

60 Site-specific spin labeling and pulsed dipolar ESR spectroscopy (PDS)

61 We have used site-directed spin labeling and pulsed electron paramagnetic resonance

62 Using site-directed spin labeling and pulsed electron-electron double resona

63 Site-directed spin labeling and pulsed electron-electron double resona

64 SH2 and iSH2 of p85alpha using site-directed spin labeling and pulsed EPR.

65 The present study employs EPR site-directed spin labeling and relaxation methods to generate a mediu

66 Arterial spin labeling and seed-based resting state functional co

67 Here, site-directed spin labeling and simulated annealing were used to locat

68 ng two biophysical techniques: site-directed spin labeling and surface plasmon resonance.

69 Participants underwent two arterial spin labeling and two blood oxygen level-dependent scans

70 terized using a combination of site-directed spin labeling and vesicle sedimentation.

71 Site-directed spin-labeling and electron paramagnetic resonance are po

72 We used site-directed spin-labeling and electron paramagnetic resonance spectr

73 We have used site-directed spin-labeling and electron paramagnetic resonance spectr

74 Site-directed spin-labeling and EPR spectroscopy were carried out for

75 Site-directed spin-labeling and Forster resonance energy transfer expe

76 Spin-labeling and multifrequency EPR spectroscopy were u

77 en; mean age, 72.9 years) underwent arterial spin-labeling and volumetric T1-weighted structural MR i

78 re prepared by overexpression of apoprotein, spin labeling, and reconstitution with hemin.

79 netic resonance imaging methods for Arterial Spin Labeling (ASL) and Blood Oxygenation Level Dependen

80 Purpose To compare arterial spin labeling (ASL) data between low- and high-grade bra

81 Arterial spin labeling (ASL) is a magnetic resonance (MR) imaging

82 collateral vessels identified using arterial spin labeling (ASL) magnetic resonance imaging, a techni

83 the emergence and potential role of arterial spin labeling (ASL) MRI, which measures cerebral blood f

84 Here, we investigated arterial spin labeling (ASL) perfusion CMR as a novel approach to

85 ate pattern recognition analysis of arterial spin labeling (ASL) perfusion maps can be used for class

86 Arterial spin labeling (ASL) provides an endogenous and completel

87 diffusion tensor imaging (DTI) and arterial spin labeling (ASL) to discriminate patients with early

88 ical magnetic resonance scans using arterial spin labeling (ASL) were performed to study the haemodyn

89 plementary neuroimaging techniques: arterial spin labeling (ASL), blood oxygen level-dependent (BOLD)

90 nges, as assessed using whole-brain arterial spin labeling (ASL), during tDCS applied to the left DLP

91 nsor imaging (DTI) acquisitions and arterial spin labeling (ASL).

92 ents obtained with different pulsed arterial spin-labeling (ASL) magnetic resonance (MR) imaging meth

93 anges after enzyme activation, site-directed spin labeling at amino acids 101, 105-109, 111, 112 and

94 of brain activity using continuous arterial spin labeling based functional magnetic resonance imagin

95 ful tool in the development of site-directed spin labeling by resolving rotamers of the nitroxide spi

96 e that restraints derived from site-directed spin labeling can contribute significantly to defining t

97 ructure determination, but EPR site-directed spin-labeling can provide a detailed medium-resolution v

98 the novel application of continuous arterial spin-labeling (CASL) magnetic resonance imaging (MRI) fo

99 l blood flow (CBF) using continuous arterial spin-labeling (CASL) MRI.

100 Site-directed spin labeling combined with electron paramagnetic resona

101 omer, called globulomer, using site-directed spin labeling complemented by other techniques.

102 pin resonance spectroscopy and site-specific spin-labeling confirm that the Tsr HAMP maintains a four

103 We used circular dichroism and site-directed spin labeling coupled with electron paramagnetic resonan

104 relating crystallographic and site-directed spin labeling data, and hence comparing crystal and solu

105 NMR studies in combination with paramagnetic spin labeling demonstrate that this interaction is media

106 , MDR769, are characterized by site-directed spin labeling double electron-electron resonance spectro

107 Here, we combine spin-labeling double electron-electron resonance (DEER)

108 S I) complex was studied using site-specific spin labeling electron paramagnetic resonance (EPR) spec

109 l activity assays coupled with site-directed spin labeling electron paramagnetic resonance (EPR) spec

110 Site-directed spin labeling electron paramagnetic resonance methods ha

111 Using site-directed spin labeling electron paramagnetic resonance spectrosco

112 Site-directed spin labeling electron paramagnetic resonance spectrosco

113 Here we report site-directed spin labeling electron paramagnetic resonance studies ex

114 terface were investigated with site-specific spin labeling electron paramagnetic resonance.

115 In this study, we use site-directed spin-labeling electron paramagnetic resonance spectrosco

116 these studies, we carried out site-directed spin-labeling electron paramagnetic resonance spectrosco

117 We here use double site-directed spin-labeling electron paramagnetic resonance spectrosco

118 Site-directed spin-labeling electron paramagnetic resonance spectrosco

119 Here, we combine site-directed spin labeling, electron paramagnetic resonance spectrosc

120 Site-directed spin labeling EPR (SDSL-EPR) was used to determine the s

121 A hybrid approach combining spin labeling EPR and cryoelectron microscopy imaging at

122 tide by using a combination of site directed spin labeling EPR and homology modeling and molecular dy

123 Site-directed spin labeling EPR spectroscopy was used to study the ope

124 Using spin labeling EPR spectroscopy, we studied a 38-residue

125 ructural biology studies using site-directed spin labeling EPR techniques.

126 ing fluorescence quenching and site-directed spin labeling EPR.

127 omplex were investigated using site-directed spin labeling EPR.

128 High-pressure site-directed spin-labeling EPR (SDSL-EPR) was developed recently to m

129 Using spin-labeling EPR, trans-SNARE complex formation was mon

130 tigated by solid-state NMR and site-directed spin labeling/EPR with a synthetic peptide, hCB(1)(T377-

131 These findings, in combination with spin-labeling/EPR spectroscopic measurements in reconsti

132 amate (Glu) and glutamine (Gln) and arterial spin labeling evaluation for rCBF.

133 -binding domain of apo-MntR, a site-directed spin labeling experiment was performed on a mutant of Mn

134 re then directly compared with site-directed spin labeling experimental results obtained by preparing

135 y a series of tetraalkylammonium ions and 2) spin labeling experiments.

136 which was further validated by site-directed spin labeling experiments.

137 Spin-labeling experiments show that the complex of the f

138 NMR and spin-labeling experiments showed that GH5_pMut bound to

139 of W14A determined by NMR and site-directed spin labeling features a flexible kink that points out o

140 dient-recalled echo to assess CMBs, arterial spin labeling for CBF, and T1- and T2-weighted imaging f

141 n healthy individuals (n=23) during arterial spin labeling functional magnetic resonance imaging (fMR

142 Pseudocontinuous arterial spin labeling functional magnetic resonance imaging and

143 ces the sensory experience, we used arterial spin labeling functional magnetic resonance imaging to a

144 Using arterial spin labeling functional magnetic resonance imaging, we

145 tivity, which was assessed by using arterial spin-labeling functional magnetic resonance imaging 4 h

146 and disease parameters, we used an arterial-spin-labeling functional MRI stress paradigm in 36 MS pa

147 Site-directed spin labeling has been employed in this work to address

148 resonance in conjunction with site-directed spin labeling has been used to probe natural conformatio

149 Site-directed spin labeling has previously been employed to detect con

150 Site-directed spin labeling has qualitatively shown that a key event d

151 ce (DEER), in conjunction with site-directed spin-labeling, has emerged in the past decade as a power

152 Pseudo-continuous arterial spin labeling imaging was used to measure resting region

153 clear magnetic resonance, combining arterial spin-labeling imaging of perfusion, and (31)P-spectrosco

154 Here we use site-directed spin labeling in combination with circular dichroism and

155 eutral pH was investigated via site-directed spin labeling in combination with conventional electron

156 Site-directed spin labeling in combination with double electron-electr

157 Site-directed spin labeling in combination with EPR is a powerful meth

158 A goal in the development of site-directed spin labeling in proteins is to correlate the motion of

159 are similar to the WT protein, site-directed spin labeling in solution reveals additional conformatio

160 pin resonance spectroscopy and site-directed spin labeling in what to our knowledge is a new approach

161 We have therefore used site-specific spin-labeling in conjunction with EPR distance measureme

162 In the current studies, site-directed spin labeling, in combination with electron paramagnetic

163 Crosslinking to TonB and site-directed spin labeling indicated that the Ton box of BtuB undergo

164 copy (EPR) in combination with site-directed spin labeling is a very powerful tool to monitor the str

165 copy (PDS) in combination with site-directed spin labeling is unique in providing nanometer-range dis

166 Site-directed spin labeling is used to determine the orientation and d

167 Here, site-directed spin labeling is used to examine a conformational equili

168 Continuous arterial spin-labeling is a noninvasive MRI method capable of mea

169 uble resonance (PELDOR), using site-directed spin labeling, is most commonly employed to accurately d

170 total blood flow to the retina with Arterial Spin Labeling Magnetic Resonance Imaging (ASL-MRI) has b

171 r for two imaging modalities-pulsed arterial spin labeling magnetic resonance imaging (PASL-MRI) and

172 Arterial spin labeling magnetic resonance imaging was used to col

173 c flow velocity was quantified by performing spin labeling measurements as a function of postlabeling

174 RE is confirmed in solution by site-directed spin labeling measurements.

175 We applied the site-directed spin labeling method of electron paramagnetic resonance

176 Using the site-directed spin labeling method of electron paramagnetic resonance

177 rane insertion by applying the site-directed spin labeling method of EPR to 13 different amino acid l

178 n by using NMR residual dipolar coupling and spin labeling methods and is based on available crystal

179 multisection continuous and pulsed arterial spin-labeling methods at 3.0 T showed a 33% improvement

180 We used cysteine-scanning and spin-labeling methods to prepare singly spin labeled rec

181 ion-recovery electron paramagnetic resonance spin-labeling methods, in which bimolecular collisions o

182 Guided by these parameters, an arterial spin labeling MR imaging approach was adapted to measure

183 Arterial spin-labeling MR imaging showed regional hypoperfusion w

184 etinas were imaged using continuous arterial spin labeling MRI at 90 x 90 x 1500 microm.

185 but no agonists, we acquired pulsed arterial spin labeling MRI at the end of each treatment period.

186 absolute myocardial blood flow (MBF) using a spin-labeling MRI (SL-MRI) method after transplantation

187 We then used arterial spin-labeling MRI to noninvasively measure CBF and asses

188 Spin labeling nucleic acids at specific sites requires t

189 Site-directed spin labeling of Cys-299 reveals a flexible hinge-like d

190 ce tools that rely on site-specific electron spin labeling of Deltatau187.

191 We used site-directed spin labeling of N-WASP peptides in conjunction with met

192 s and distance restraints from site-specific spin labeling of Pdx has been applied.

193 Here, we used site-directed spin labeling of recombinant tau in conjunction with ele

194 Using site-directed spin labeling of Ser(155)Cys with a nitroxide side chain

195 ed experimental data involving site-directed spin labeling of the intact RLC bound to the two-headed

196 f monocysteine variants and by site-specific spin labeling of the Q-helix followed by EPR-based inter

197 Site-specific spin labeling of the recombinant protein allowed the mea

198 Site-directed spin labeling of the SCAMP-E peptide indicates that the

199 Site-directed spin labeling of this peptide shows that the position an

200 Site-directed spin-labeling of proteins whereby the spin-label methyl

201 We have used site-specific spin-labeling of single cysteine mutations within a wate

202 We used pulsed continuous arterial spin labeling (pCASL), a perfusion magnetic resonance im

203 Here, we combined arterial spin labeling perfusion and blood oxygen level-dependent

204 Arterial spin labeling perfusion and blood-oxygen level-dependent

205 ndividuals with schizophrenia using arterial spin labeling perfusion MRI.

206 ood-oxygenation-level-dependent and arterial-spin-labeling perfusion contrasts to investigate the rel

207 (CBF) was measured with continuous arterial spin-labeling perfusion magnetic resonance (MR) imaging

208 noninvasive neuroimaging technique, arterial spin-labeling perfusion MRI, to measure cerebral blood f

209 and derivatives thereof using site-directed spin labeling, pressure-resolved double electron-electro

210 three-dimensional pulsed-continuous arterial spin labeling provided measurements of regional cerebral

211 We exploited arterial spin-labeling quantitative perfusion imaging and a newly

212 Moreover, NMR and spin-labeling results from the study of the nucleosome i

213 Recent site-directed spin labeling (SDSL) and double electron-electron resona

214 context of the ribozyme using site-directed spin labeling (SDSL) and electron paramagnetic resonance

215 We have used site-directed spin labeling (SDSL) and electron paramagnetic resonance

216 Here, site-directed spin labeling (SDSL) and electron paramagnetic resonance

217 ombine ESEEM spectroscopy with site-directed spin labeling (SDSL) and X-ray crystallography in order

218 using circular dichroism (CD), Site-Directed Spin Labeling (SDSL) coupled to EPR spectroscopy, and en

219 Site-directed spin labeling (SDSL) electron paramagnetic resonance (EP

220 Site-directed spin labeling (SDSL) electron paramagnetic resonance (EP

221 Here, using site-directed spin labeling (SDSL) electron paramagnetic resonance (EP

222 For this study, we used a site-directed spin labeling (SDSL) experimental approach to investigat

223 Site-directed spin labeling (SDSL) has potential for mapping protein f

224 osecond backbone dynamics with site-directed spin labeling (SDSL) in soluble proteins has been well e

225 Spectroscopic studies using site-directed spin labeling (SDSL) indicate that the N-terminus of Btu

226 Here, site-directed spin labeling (SDSL) is used to show that a range of sol

227 The traditional site-directed spin labeling (SDSL) method, which utilizes cysteine res

228 en carried out using site directed nitroxide spin labeling (SDSL) of cysteine residues.

229 Site-directed spin labeling (SDSL) studies revealed that C265 lies clo

230 In the present study, site-directed spin labeling (SDSL) together with double electron-elect

231 The method of site-directed spin labeling (SDSL) utilizes a stable nitroxide radical

232 Here, site-directed spin labeling (SDSL) was used to determine the position

233 Site-directed spin labeling (SDSL) was used to examine and compare tra

234 Site-directed spin labeling (SDSL) was used to explore the structural

235 etic resonance (EPR) method of site-directed spin labeling (SDSL) with double electron-electron reson

236 In site-directed spin labeling (SDSL), a nitroxide moiety containing a st

237 he hemolytic anemia phenotype, site-directed spin labeling (SDSL), in combination with continuous wav

238 In site-directed spin labeling (SDSL), local structural and dynamic infor

239 Site-directed spin labeling (SDSL), the site-specific incorporation of

240 two mutant cycle analysis with site-directed spin labeling (SDSL).

241 With an arterial spin labeling sequence, three networks were first identi

242 e-chain interactions, and that site-directed spin labeling should be a powerful means of monitoring c

243 photoconversions monitored by site-directed spin labeling show that opposite structural changes in h

244 or resonances more than 20 residues from the spin-labeling site.

245 ctive insights into these processes, but new spin-labeling strategies are needed.

246 ng the phenomena which they measure, but our spin labeling strategy has reported common kinetic theme

247 binding interface in MHV with site-directed spin labeling studies consistent with a model in which t

248 Remarkably, site-directed spin labeling studies reveal that these fibrils possess

249 ng environments encountered in site-directed spin labeling studies.

250 the use of this technique for site-directed spin-labeling studies of biologically relevant samples,

251 The results of these site-directed spin-labeling studies reveal that phosphorylation at a d

252 Spin-labeling studies show that residue A62 of MMOB is l

253 Site-directed spin-labeling studies showed that the N-terminus of the

254 Here we describe site-directed spin-labeling studies that identify interactions of LF w

255 A spin-labeling study of interactions of a fusion peptide

256 The method relies on sparse spin-labeling, supplemented by deuteration of protein an

257 d with echo-planar imaging using an arterial spin labeling technique and a custom-made eye coil at 7

258 s in DNA are studied using the site-directed spin labeling technique.

259 tem to explore and enhance the site-directed spin labeling technique.

260 A continuous arterial spin-labeling technique with an amplitude-modulated cont

261 easured using the pseudo-continuous arterial-spin-labeling technique with background suppression and

262 Site directed spin-labeling technology has enabled the insertion of ni

263 In site-directed spin labeling, the relative solvent accessibility of spi

264 simulations were combined with site-directed spin labeling to define its structure and dynamics.

265 Here, we use site-specific spin labeling to demonstrate that relaxation enhancement

266 We generated seven mutants suitable for spin labeling to enable application of pulsed EPR techni

267 iol-specific cross-linking and site-directed spin labeling to identify specific protein-protein assoc

268 Here, we used site-directed spin labeling to map the conformation of a pRNA three-wa

269 e imaging based on pseudocontinuous arterial spin labeling to measure CBF at normocapnia (ie, breathi

270 a placebo-controlled study, we used arterial spin labeling to measure IN-OT-induced changes in restin

271 e validity of this model using site-directed spin labeling to obtain long-range distance information

272 n resonance spectroscopy using site-directed spin labeling to understand the structure and interfacia

273 This work points the way for spin-labeling to investigate oligonucleotide-protein com

274 tudy utilizes site-directed fluorescence and spin-labeling to map out the membrane docking surface of

275 ce spectroscopy, together with site-directed spin labeling, to investigate the structural features of

276 We used site-directed spin-labeling together with electron spin-resonance line

277 Site-directed spin labeling utilizes site-specific attachment of a sta

278 performed using velocity-selective arterial spin labeling (VSASL) and 3D image acquisition with whol

279 Site-directed spin labeling was carried out on the C2 domain of cytoso

280 thod based on the technique of site-directed spin labeling was developed to experimentally map shapes

281 Continuous arterial spin labeling was interleaved with TMS to directly asses

282 Site-directed spin labeling was used to determine the membrane orienta

283 Here, site-directed spin labeling was used to examine the complex formed bet

284 Here, site-directed spin labeling was used to examine the structural basis f

285 Here, site-directed spin labeling was used to generate models for the soluti

286 emic clamp sessions in which pulsed arterial spin labeling was used to measure regional cerebral bloo

287 lectron paramagnetic resonance site-directed spin labeling was used to monitor loss of tertiary struc

288 Site-directed spin labeling was used to obtain bilayer depth restraint

289 Here, site-directed spin labeling was used to probe the solution structures

290 gnetic resonance imaging technique (arterial spin labeling) was used to quantify spatial pulmonary bl

291 Using site-directed spin labeling, we demonstrated that the pressure- and te

292 Using site-directed spin labeling, we found that the local structure around

293 Using arterial spin labeling, we measured resting-state cerebral blood

294 ectroscopy in combination with site-directed spin labeling, we show that familial PD-associated varia

295 mages and perfusion images by using arterial spin labeling were obtained for comparison.

296 The cysteine mutations used for spin-labeling were distributed throughout the cytosolic

297 MRI arterial spin labeling, white matter hyperintensities (WMHs) and

298 oped an approach that combines site-directed spin labeling with continuous wave and pulsed EPR to inv

299 Here, we used site-directed spin labeling with power saturation electron paramagneti

300 el system, we introduce a method of parallel spin-labeling with paramagnetic and diamagnetic labels a