ライフサイエンスコーパス: spinal motoneuron

1 , which recognizes the surfaces of zebrafish spinal motoneurons.

2 ssed in both cerebellar Purkinje neurons and spinal motoneurons.

3 CNTFRalpha protein is androgen-regulated in spinal motoneurons.

4 highly enriched cultures of embryonic chick spinal motoneurons.

5 s onto (1) CRNs, (2) neurons in PnC, and (3) spinal motoneurons.

6 cleus reticularis pontis caudalis (PnC), and spinal motoneurons.

7 rossed projection transmits more reliably to spinal motoneurons.

8 conductance and induces irregular firing in spinal motoneurons.

9 cal characteristics as ESCMNs and endogenous spinal motoneurons.

10 maging, we found that Bk strongly sensitizes spinal motoneurons.

11 y more drive to progressively less excitable spinal motoneurons.

12 by AADC cells increases the excitability of spinal motoneurons.

13 a (VMM) and spinal cord that in turn inhibit spinal motoneurons.

14 increased expression of the p75 receptor by spinal motoneurons.

15 ce changes, through selective recruitment of spinal motoneurons.

16 GABA and AMPA quantal amplitude in embryonic spinal motoneurons.

17 lopment of the mammalian pituitary gland and spinal motoneurons.

18 tical neurons the role normally performed by spinal motoneurons.

19 as corticospinal tract (CTS) projections to spinal motoneurons.

20 the control of cortical neurons rather than spinal motoneurons.

21 This plasticity optimizes the control of spinal motoneurons.

22 directly cause muscle contraction just like spinal motoneurons.

23 nicotine delays the development of secondary spinal motoneurons.

24 depolarizing- hyperpolarizing potentials in spinal motoneurons; (2) the depolarizing potentials decr

25 ated the synaptology of retrogradely labeled spinal motoneurons after injection of horseradish peroxi

26 The dendrites of spinal motoneurons amplify synaptic inputs to a marked d

27 sent data using VSC 4.1 cell line, a ventral spinal motoneuron and neuroblastoma hybrid cell line.

28 re characterized by similarities to those of spinal motoneurons and by their relatively large numbers

29 Spinal motoneurons and dorsal horn neurons were isolated

30 ession are seen in certain cranial nerve and spinal motoneurons and in small populations of neurons i

31 Using whole-cell patch-clamp recordings from spinal motoneurons and interneurons, we describe a long-

32 tone depends on the level of excitability of spinal motoneurons and interneurons.

33 n is essential for the normal development of spinal motoneurons and is required for the development o

34 in vivo paired recordings between identified spinal motoneurons and skeletal muscle cells in larval z

35 related to both the descending inhibition of spinal motoneurons and suppression of activity in supras

36 y imagery-related subthreshold activation of spinal motoneurons and/or interneurons, rather than by l

37 ker currents can act as leak conductances in spinal motoneurons, and also control long-term modulatio

38 (approximately 40%; [21]) and cultured P7-P8 spinal motoneurons (approximately 70%).

39 The dendrites of spinal motoneurones are highly active, generating a stro

40 Although spinal motoneurons are a major target of spinal interneu

41 Mammalian spinal motoneurons are considered to be output elements

42 Spinal motoneurons are highly vulnerable in amyotrophic

43 uscle cell ablation revealed that almost all spinal motoneurons are lost by E18.5, providing strong e

44 Spinal motoneurons are more susceptible to AMPA receptor

45 In larval zebrafish, spinal motoneurons are recruited in a topographic gradie

46 kinase in these pathways, have twice as many spinal motoneurons as do their wild-type littermates.

47 In contrast to spinal motoneurons, axonal L-type channels enhance firin

48 Spinal motoneurons become hyperexcitable after SCI, but

49 tinuous communication between the cortex and spinal motoneurons, but the neurophysiological basis of

50 We elicited repetitive discharges in cat spinal motoneurones by injecting noisy current waveforms

51 upscaling could be triggered in chick embryo spinal motoneurons by complete blockade of spiking or GA

52 gene (Adv.EFalpha-NT3) was delivered to the spinal motoneurons by retrograde transport through the s

53 ynaptic inhibition (I) and excitation (E) to spinal motoneurons can provide an important insight into

54 stem (hiPS) cells into midbrain dopamine and spinal motoneurons confirms the robustness and general a

55 rojects to cortical neurons, and projects to spinal motoneurons controlling hand muscles.

56 In spinal motoneurones cultured from presymptomatic mice ex

57 In spinal motoneurons, dendrites have voltage-activated per

58 vealed that the excitatory synaptic input to spinal motoneurones during fictive swimming in Xenopus t

59 itation to EPSPs measured in Xenopus tadpole spinal motoneurones during swimming.

60 , providing strong evidence that survival of spinal motoneurons during embryogenesis is dependent on

61 e compare conductance and firing patterns in spinal motoneurons during network activity for scratchin

62 control the gain of motor cortical inputs to spinal motoneurons during precision grip of a small obje

63 High-conductance states were observed in spinal motoneurons during rhythmic motor behavior.

64 regular firing, and increased conductance in spinal motoneurons during scratch and swim network activ

65 This was previously shown for spinal motoneurons during scratching.

66 hibition decreased during precision grip and spinal motoneuron excitability remained unchanged in all

67 e findings indicate that (1) embryonic avian spinal motoneurons express functional PAR-1 and (2) acti

68 ppression of voluntary electromyography) and spinal motoneurons (F-waves) in an intrinsic hand muscle

69 ppression of voluntary electromyography) and spinal motoneurons (F-waves) in intrinsic hand muscles w

70 We generated spinal motoneurons from embryonic stem (ES) cells to det

71 glycine receptor (GlyR)-mediated currents in spinal motoneurons from these transgenic mice.

72 Previous work in spinal motoneurons had shown that reducing spontaneous n

73 Degeneration of spinal motoneurons has been well documented in amyotroph

74 docaine in vivo triggers synaptic scaling in spinal motoneurons; here we show that AMPAergic scaling

75 escending synaptic inputs to multifunctional spinal motoneurons (i.e., involved in respiration and lo

76 n of tau in hippocampal CA3 Mossy fibers and spinal motoneurons in a hypothermia-induced tau hyperpho

77 We find deficits in retrograde labeling of spinal motoneurons in both a knock-in (KI) and a myogeni

78 In contrast to spinal motoneurons in both cats and rats, the larger DRG

79 and cholinergic immunoreactive terminals on spinal motoneurons in mice expressing a mutant form of h

80 lopment alters the dendritic arborization of spinal motoneurons in ovo.

81 stence of commissural neurons with access to spinal motoneurons in primate cervical spinal cord that

82 rt survival of no more than 10% of embryonic spinal motoneurons in the absence of muscle-derived sign

83 use of intracellular recording techniques in spinal motoneurons in the adult cat.

84 ding techniques, we examined the response of spinal motoneurons in the cat to electrical stimulation

85 gotes showed an approximate 60% reduction of spinal motoneurons in the lumbar region and a more than

86 801 had no effect on non-androgen-responsive spinal motoneurons in the neighboring retrodorsolateral

87 Primary motoneurons, the earliest developing spinal motoneurons in zebrafish, have highly stereotyped

88 ntage of a topographic map of recruitment of spinal motoneurons in zebrafish.

89 postsynaptic potentials (IPSPs), E(IPSP), in spinal motoneurons, increases the cell membrane expressi

90 Second, spinal motoneurons innervating one of these muscles, the

91 mpensatory increases in synaptic strength of spinal motoneuron inputs.

92 ty may modulate descending synaptic drive to spinal motoneurons involved in both respiration and loco

93 The rhythmic firing behavior of spinal motoneurons is a function of their electrical pro

94 s that inhibitory interneuron innervation of spinal motoneurons is abnormal in an amyotrophic lateral

95 study showed that glycinergic innervation of spinal motoneurons is deficient in an ALS mouse model ex

96 ergic (5-HT) and noradrenergic (NA) input to spinal motoneurons is essential for generating plateau p

97 postnatal period, dendritic growth in other spinal motoneurons is regulated by N-methyl-D-aspartate

98 nificance of neurotrophin mRNA expression in spinal motoneurons is supported by immunohistochemical l

99 Spinal motoneurons, like many neurons, respond with repe

100 These results clarify new aspects of spinal motoneurons malfunction in ALS.

101 the greater AMPA receptor current density of spinal motoneurons may be sufficient to account for thei

102 les of the chick embryo during the period of spinal motoneuron (MN) programmed cell death, and its re

103 Embryonic lumbar spinal motoneurons (MNs) are characterized by a period o

104 ipulate the enlargement of EPSPs produced in spinal motoneurons (MNs) by IA afferents 3 d after nerve

105 ge-dependent morphological changes of lumbar spinal motoneurons (MNs) in neonatal Swiss-Webster mice

106 Spinal motoneurons (MNs) in the chick embryo undergo pro

107 The death of cranial and spinal motoneurons (MNs) is believed to be an essential

108 and physiological properties of adult turtle spinal motoneurons (MNs) vs. interneurons (INs).

109 cution relies on precise input processing by spinal motoneurons (MNs).

110 mediation of the postsynaptic inhibition of spinal motoneurons necessary for the motor atonia of rap

111 Regular firing in spinal motoneurons of red-eared turtles (Trachemys scrip

112 mRNA for each of these neurotrophins within spinal motoneurons of the adult and in early postnatal d

113 It is well documented that the lumbar spinal motoneurons of the chick embryo undergo a period

114 e show that, of the two classes of zebrafish spinal motoneurons, only the later growing secondary mot

115 iPSCMNs and how they compare with endogenous spinal motoneurons or embryonic stem cell-derived motone

116 ation of PSCs into specialized cells such as spinal motoneurons or midbrain dopamine (DA) neurons has

117 Since the majority of inputs to spinal motoneurones originate from intrinsic spinal prem

118 de-afferented red nucleus and the denervated spinal motoneurons (p<0.05).

119 areas appear to have direct connections with spinal motoneurons, particularly those innervating muscl

120 ts that alterations in ionic conductances in spinal motoneurones, specifically the manifestation of p

121 The dependence of developing spinal motoneuron survival on a soluble factor(s) from t

122 Patch clamp recordings from spinal motoneurons tested whether gap junction blockers

123 ese areas produce appropriate control of the spinal motoneurons that activate muscles.

124 recruitment pattern and output properties of spinal motoneurons that can together generate appropriat

125 vide a significant, direct synaptic input to spinal motoneurons that innervate hindlimb muscles.

126 cal and morphological properties of neonatal spinal motoneurons that occur by 10 d after birth, long

127 is also required at much earlier stages for spinal motoneurons to accurately execute their first maj

128 the outcome of CNS activity from control of spinal motoneurons to, instead, control of the cortical

129 and distribution of the whole population of spinal motoneurons, to define the extent of their centra

130 tions between corticospinal tract fibres and spinal motoneurones undergo activity-dependent reorganiz

131 tions between corticospinal tract fibres and spinal motoneurones undergo activity-dependent reorganiz

132 atal mouse that mediates synaptic effects on spinal motoneurons via parallel uncrossed and crossed pa

133 BSA on the retrograde response of adult rat spinal motoneurones were quantified at 7 days.

134 escending synaptic inputs to multifunctional spinal motoneurons were frequency-dependent and heterosy

135 Spinal motoneurons which innervate muscles associated wi

136 Humans have direct cortical connections to spinal motoneurons, which bypass spinal interneurons and

137 of synapses between corticospinal axons and spinal motoneurons, which can be modulated by the precis

138 which degenerate in Parkinson's disease, for spinal motoneurons, which die in Lou Gehrig's disease (A

139 Transduction of spinal motoneurons with Adv.EFalpha-NT3 resulted in a si