ライフサイエンスコーパス: spinally

1 had an opposite effect similar to that seen spinally.

2 sence of spinal TNF-alpha, IL-6 was released spinally.

3 ord dorsal horn and activates GABA receptors spinally.

4 eralgesia by activation of GABA(A) receptors spinally.

5 cyclase or PKA inhibitors were administered spinally 24 hr, but not 1 week, after injection of capsa

6 ctivity supraspinally (3.4 nmol, i.c.v.) and spinally (4.3 nmol, i.t.).

7 Spinally administered 8-bromo-cAMP resulted in a similar

8 We spinally administered DOR and mu opioid receptor (MOR) s

9 Remote cortical effects of spinally administered growth factors could "prime" the n

10 ve demonstrated that the analgesic effect of spinally administered lipid-soluble opioids is due in pa

11 In addition, the potency of spinally administered morphine was decreased in this tes

12 so contribute to the potency and efficacy of spinally administered morphine.

13 Spinally administered muscarinic receptor agonists or ac

14 Spinally administered muscarinic receptor agonists or ac

15 a suggest that the nociceptive properties of spinally administered nAChR agents are not mediated by e

16 We investigated the effects of spinally administered ondansetron (10, 50 and 100 microg

17 decreases the spinal cord bioavailability of spinally administered opioids.

18 Both spinally and peripherally induced priming is prevented b

19 Cardiac arrest was induced in 11 spinally anesthetized dogs and 8 sham-control animals; c

20 In stark contrast, animals with a spinally applied dopaminergic lesion showed intact IL-6-

21 z EA-produced anti-hyperalgesia were blocked spinally by mu- and delta- but not kappa-receptor antago

22 hat gabapentin administered systemically and spinally can effectively relieve tactile allodynia in th

23 o organs involve the participation of shared spinally derived pathways, allowing mechanisms of commun

24 We find that a spinally directed lesion of dopaminergic neurons reverse

25 ular mechanisms of late LTP and suggest that spinally directed PKMzeta inhibitors may offer therapeut

26 Here we show that spinally expressed Kalirin-7 is required for persistent

27 ylate cyclase or protein kinase A inhibitors spinally follows a similar pattern with reversal at 24 h

28 Our results show that spinally formed S1P signals at least in part by (1) modu

29 For spinally hemisected animals, we electrically stimulated

30 of 30 day old male Sprague-Dawley rats were spinally hemisected at T13 and 28 days later received ei

31 otomized, and pump-ventilated control and C2 spinally hemisected rats at 2, 4, and 8 weeks after inju

32 Spinally induced priming is detected not only when prost

33 zed, vagotomized, paralyzed, ventilated, and spinally injured (C2 hemisection) rats that were exposed

34 hether the unique anatomical presentation in spinally injured rats and mice is associated with a spec

35 papilla at the lesion site improves gait in spinally injured rats and reduces glial reactivity.

36 renic pathways contribute to tidal volume in spinally injured rats, spontaneous breathing was measure

37 In chloralose-anesthetized, spinally intact and spinally transected rats, we recorde

38 most T(10) interneurons, but stimulation in spinally intact rats increased RSNA while still reducing

39 in the regulation of sympathetic activity in spinally intact rats.

40 ce of correlated neurons was much smaller in spinally intact than in spinally transected rats.

41 hat endogenously released dopamine acts upon spinally located D2-like receptors, leading to a rapid i

42 mming in spinalised preparations, suggesting spinally located dopamine receptors.

43 As cortical and spinally mediated activity is developmentally regulated,

44 To establish the cellular sites for the spinally mediated analgesic effects of MOR activation an

45 The induction of a spinally mediated antinociception was accompanied by an

46 emonstrate the importance of NK receptors in spinally mediated behavioral plasticity.

47 lyol pathway activity in the pathogenesis of spinally mediated hyperalgesia.

48 whether microglial activation is governed by spinally mediated increases in the microglial activator

49 ct of stimulus exposure was assessed using a spinally mediated instrumental response, wherein spinall

50 to modulation of inhibitory circuits within spinally mediated pain pathways and suggest that extrasy

51 icits in RDD may help identify patients with spinally mediated painful diabetic neuropathy who may re

52 jury results in a lasting reduction in adult spinally mediated plasticity resembling the deficit seen

53 of a specific spinal interneuronal circuit: spinally mediated reciprocal Ia inhibition.

54 Moreover, the involvement of glutamate in spinally mediated tolerance to morphine suggests that gl

55 ic effects might be supra- rather than intra-spinally mediated, and that phosphorylation of the NR2B

56 ed anesthetics; for immobilization, which is spinally mediated, these data implicate motoneurons as t

57 tiple opioids that are commonly administered spinally produce analgesia by uptake into the systemic c

58 Our results show that the spinally projected cathecholaminergic C1 and non-C1 resp

59 nce for a direct pathway from PAG neurons to spinally projecting A7 neurons requires ultrastructural

60 se RVL vasomotor neurones were identified as spinally projecting by antidromically activating their a

61 ns in the PAG must project to, and activate, spinally projecting catecholamine neurons located in the

62 ynapses with noradrenergic A7 neurons, these spinally projecting catecholamine neurons may mediate pa

63 Moreover, ablating spinally projecting dopaminergic neurons after the resol

64 2 evokes complex activation of predominantly spinally projecting extrinsic intestinal afferent nerves

65 cro-opioid receptors excites a population of spinally projecting LC neurons by preferential inhibitio

66 (muOR) in regulation of the excitability of spinally projecting LC neurons has not been investigated

67 mu-opioid receptors excites a population of spinally projecting LC neurons through attenuation of ga

68 Spinally projecting LC neurons were retrogradely labeled

69 rts, suggest that neurons in the LH activate spinally projecting methionine enkephalin neurons, as we

70 tigate whether hypothalamic vasopressinergic spinally projecting neurones are activated during increa

71 he activation of c-fos protein expression in spinally projecting neurons during intravenous LPS fever

72 Nearly 30% of spinally projecting neurons in the VMM were immunoreacti

73 A similar percentage of spinally projecting neurons in the VMM were immunoreacti

74 Spinally projecting neurons of the ventromedial medulla

75 Finally, spinally projecting neurons were found predominantly on

76 We also found KOR immunoreactivity in many spinally projecting neurons within the RVM of female rat

77 RVM produces the antinociception mediated by spinally projecting neurons.

78 olumbar junction of the spinal cord to label spinally projecting neurons.

79 two markers was even higher (89%) for VGLUT3 spinally projecting neurons.

80 All anesthetics tested induced Fos in the spinally projecting noradrenergic A5-7 groups.

81 lamine cell groups that are known to contain spinally projecting noradrenergic neurons.

82 NO potentiates GABAergic synaptic inputs to spinally projecting PVN neurones through a cGMP-protein

83 ing effect of NO on synaptic GABA release to spinally projecting PVN neurones.

84 hyl-d-aspartate receptor (NMDAR) activity in spinally projecting PVN neurons and sympathetic vasomoto

85 substantial new evidence that Ang II excites spinally projecting PVN neurons by attenuation of GABAer

86 tic currents (EPSCs) of retrogradely labeled spinally projecting PVN neurons displayed a larger ampli

87 EPSCs (AMPAR-EPSCs) of retrogradely labeled spinally projecting PVN neurons exhibited a linear curre

88 puff NMDA-elicited currents were recorded in spinally projecting PVN neurons in SHRs and male Wistar-

89 icantly reduced the basal firing activity of spinally projecting PVN neurons in spontaneously hyperte

90 puff NMDA-elicited currents were recorded in spinally projecting PVN neurons in spontaneously hyperte

91 The spinally projecting PVN neurons were retrogradely labell

92 t also eliminated DHPG-induced excitation of spinally projecting PVN neurons.

93 excitatory and inhibitory synaptic inputs to spinally projecting PVN neurons.

94 medullary reticular formation as well as the spinally projecting raphe nuclei increased their project

95 to have both direct and indirect effects on spinally projecting RVM cells in general, and on seroton

96 ely the expression of MOR1 and DOR1 mRNAs in spinally projecting RVM neurons including serotonergic (

97 In addition, spinally projecting RVM neurons were significantly large

98 results suggest that significant numbers of spinally projecting serotonergic and nonserotonergic neu

99 acological and behavioral data suggests that spinally projecting serotonergic cells mediate opioid an

100 A small percentage of spinally projecting serotonergic neurons was immunoreact

101 oinjection of morphine into the RVM and that spinally projecting serotonergic RVM neurons express mu-

102 how acetylcholine influences the activity of spinally projecting SLD (SLDsp) neurons.

103 The dendritic arbors of spinally projecting TH neurons from sedentary rats were

104 s project to rostral ventrolateral medullary spinally projecting vasomotor neurones.

105 r activity by increasing the excitability of spinally-projecting neurons and identifies NK1 receptors

106 The paraventricular nucleus (PVN) contains spinally-projecting neurons implicated in fine-tuning th

107 ated in part by the subsequent activation of spinally-projecting neurons in the RVM.

108 ated in part by the subsequent activation of spinally-projecting noradrenergic neurons in the A7 cell

109 ted near the A7 cell group to inactivate the spinally-projecting noradrenergic neurons.

110 7 cell group to block synaptic activation of spinally-projecting noradrenergic neurons.

111 antinociception that is mediated in part by spinally-projecting noradrenergic neurons.

112 rophic effects of GABA on a subpopulation of spinally-projecting noradrenergic neurons.

113 d in the RVM to block synaptic activation of spinally-projecting RVM neurons.

114 Spinally-projecting serotonergic neurons in the LH have

115 COX-1 inhibitor given systemically, but not spinally, reduced carrageenan-evoked thermal hyperalgesi

116 Increased facilitation by spinally released serotonin has been suggested by demons

117 eal that many of the ligands are more potent spinally than supraspinally and devoid of tolerance.

118 We find that a mixed D1/D5 agonist given spinally to primed mice activates a subset of neurons in

119 mbar spinal cord in postnatal day 5 neonatal spinally transected (ST) rats corrected errors in hindli

120 includes neurogenesis, larval lampreys were spinally transected and injected with 5-bromo-2&prime-de

121 Steroid implants were made in normal or spinally transected fish.

122 Hindlimb steps of spinally transected pups that received L-DOPA or quipazi

123 the level of hindlimb loading provided to a spinally transected rat strongly influences the quantity

124 ally mediated instrumental response, wherein spinally transected rats are given legshock whenever one

125 Previous research has demonstrated that spinally transected rats can acquire a prolonged flexion

126 For example, spinally transected rats given a legshock each time the

127 ng of the lumbar spinal circuitry in Trained spinally transected rats involved adaptations in the glu

128 Dorsolateral cervical stimulation in spinally transected rats reduced both RSNA and the activ

129 Spinally transected rats were administered 900 fixed spa

130 In acutely spinally transected rats, we have described a population

131 chloralose-anesthetized, spinally intact and spinally transected rats, we recorded ongoing RSNA and t

132 was much smaller in spinally intact than in spinally transected rats.

133 ex because a similar response is observed in spinally transected rats.

134 ate and glycine in the lumbar spinal cord of spinally transected rats.