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1 ituated in proximity to one of the two SPBs (spindle pole bodies).
2 this function involves association with the spindle pole body.
3 ub2p/Bfa1p are located on the daughter-bound spindle pole body.
4 e gammaTuRC and anchors the gammaTuRC to the spindle pole body.
5 s to interact with Bbp1p, a component of the spindle pole body.
6 l early mitosis when they co-localize at the spindle pole body.
7 STU2 encodes a component of the spindle pole body.
8 r3p-GFP was found at the nuclear side of the spindle pole body.
9 DNA replication but unable to duplicate the spindle pole body.
10 identify a unique link between NuA4 and the spindle pole body.
11 hat tethers the gamma-tubulin complex to the spindle pole body.
12 this domain alone is able to localize to the spindle pole body.
13 uch as nuclear pore complexes (NPCs) and the spindle pole body.
14 nship between nuclear pore complexes and the spindle pole body.
15 se, FgCdc14-GFP localized to the nucleus and spindle-pole-body.
16 Most components of the MEN localize to spindle pole bodies.
17 the speed and acceleration of two separating spindle pole bodies.
18 bundles of cytoplasmic microtubules from the spindle pole bodies.
19 recent birth scar, not with asymmetry in the spindle pole bodies.
20 ble microtubules were observed unattached to spindle pole bodies.
21 induce lethality in mutants defective in the spindle pole bodies.
22 quently localizes to the mitotic spindle and spindle pole bodies.
23 P), to intranuclear spindle microtubules and spindle pole bodies.
24 tation of sister centromeres toward opposite spindle pole bodies.
25 clb4 mad2 cells accumulated with unseparated spindle pole bodies.
26 tach to spindles emanating from the opposite spindle pole bodies.
27 f the nucleus or coalescence of the parental spindle pole bodies.
28 ulation in diploid Saccharomyces cerevisiae, spindle pole bodies acquire the so-called meiotic plaque
29 ughout the cell, becomes concentrated at the spindle pole bodies after the meiosis I division, and at
30 h Cdc2 protein kinase activity and separated spindle pole bodies, an arrest state similar to that obs
31 antibodies shows that CaCse4p localizes near spindle pole bodies, analogous to the localization patte
32 have reduced amounts of gamma-tubulin at the spindle pole bodies and nucleation of spindle microtubul
33 rt of anaphase, GFP-Glc7p accumulated at the spindle pole bodies and remained there until cytokinesis
34 the nucleus in G2 and is mobilized onto the spindle pole bodies and spindle midzone at anaphase onse
36 ired for self-association and for binding to spindle pole bodies and that this domain is essential fo
37 ation is required for proper localization at spindle pole bodies and the cell division site, E3 ligas
39 ase transition and a fraction remains at the spindle pole bodies and the spindle midzone in anaphase
41 stent with aggregation of centromeres at the spindle pole body and compartmentalization of individual
42 nase that is required for duplication of the spindle pole body and for the spindle assembly checkpoin
43 f19-HAp localizes to the nuclear face of the spindle pole body and genetically interacts with a spind
44 enesis, the temporal appearance of different spindle pole body and spindle structures, the cell cycle
46 hree of these locations, the hyphal tip, the spindle pole body and the nucleus, correlate with previo
47 usion protein to the cytoplasmic side of the spindle pole body and used a kar9 mutant to show that ce
48 tion of the mitochondria was tethered to the spindle-pole bodies and moved to the cellular ends durin
49 a forespore membrane (FSM) initiates at each spindle-pole body and extends to form the spore envelope
51 ins Mpc70p localizes to only two of the four spindle pole bodies, and these are always nonsisters.
52 ulation of Nuf1p/Spc110p, a component of the spindle pole body, and in bud growth, by binding Myo2p,
53 tein markers to examine the dynamics of MTs, spindle pole body, and the nuclear envelope in living ce
54 perhaps by altering its localization to the spindle pole body, and, thus, that gamma-tubulin plays a
55 iae, vesicles transported to the vicinity of spindle pole bodies are fused to each other to generate
56 The paper also focuses attention on the two spindle pole bodies as potential sites for regulation of
57 the first evidence that the nuclear envelope spindle pole body assembly component Mps3p performs a fu
58 times in contractile rings and 7500 times in spindle pole bodies at certain times in the cell cycle.
59 ecause TINA is modified and localizes to the spindle pole bodies at mitosis, and lack of TINA causes
60 d chromatin was observed to segregate to the spindle pole bodies at rates greater than centromere to
61 re, we show that Sid2p is a component of the spindle pole body at all stages of the cell cycle and lo
63 C-terminal coiled-coil domains localized to spindle pole bodies but not along spindle microtubules.
64 e An-Nup84-120 complex locates to the NE and spindle pole bodies but, unlike vertebrate cells, does n
66 mplicated three of these genes in centrosome/spindle pole body, centromere, and cohesion function.
67 yces cerevisiae, the cytoplasmic face of the spindle pole body changes from a site of microtubule ini
68 w that the localization of Spc72p within the spindle pole body changes throughout the cell cycle and
72 novel insights into the mechanism by which a spindle pole body component, when mutated, contributes t
73 The yeast Xgrip109 homologue, Spc98, is a spindle-pole body component that interacts with gamma tu
74 sickened by the mutation of genes coding for spindle pole body components and that spo7Delta was synt
75 leading to changes in nuclear shape, loss of spindle pole body components from the nuclear envelope,
78 Our data can be explained by conservative spindle pole body distribution in which the two newly sy
79 ding of the recombinant Tub4p complex to the spindle pole body docking protein Spc110p affects its nu
80 f microtubule-organizing activity to the the spindle pole body, driven by the novel coiled-coil prote
82 lope SUN domain protein that is required for spindle pole body duplication and for sister chromatid c
83 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint reg
86 nsertion into the nuclear membrane or affect spindle pole body duplication by altering the nuclear en
87 ly, suggesting that under certain conditions spindle pole body duplication can occur via an Mps3p-ind
88 report that overexpression of NDC1 leads to spindle pole body duplication defects indistinguishable
90 o shown that germ tubes can evaginate before spindle pole body duplication, chitin ring formation, an
92 Although kic1 mutants were not defective for spindle pole body duplication, they exhibited a variety
94 stress response; (2) ESCRT factors regulate spindle-pole-body duplication; and (3) a membrane-protei
96 and found that Mob1p first localized to the spindle pole bodies during mid-anaphase and then localiz
97 observed that the asymmetric behavior of the spindle pole bodies during spindle assembly was lost in
100 e strengths of microtubule attachment to the spindle pole body during these stages of the cell cycle.
101 calization and roles for Hei10 in centrosome/spindle pole body dynamics and associated nuclear traffi
102 in sealing the nuclear envelope in mammals, spindle pole body dynamics in fission yeast, and surveil
103 visiae, entry into S phase and separation of spindle pole bodies each require CDC4 and CDC34, which e
104 clear pore complexes either compete with the spindle pole body for insertion into the nuclear membran
105 a diffusion based mechanism, centred on the spindle pole body, for the coordination of DNA replicati
108 MEN genes CDC5, CDC14, CDC15, and DBF2, and spindle pole body gene NUD1 but was independent of MYO1.
109 ue to lack of nimQMCM2 continue to replicate spindle pole bodies in the absence of DNA replication an
113 anized in the nuclear envelope, known as the spindle pole body in yeast (analogous to the centrosome
116 ontrast to its important role at the central spindle pole body, in none of these cases is it clear th
119 absence of Taz1, telomere clustering at the spindle pole bodies is disrupted, meiotic recombination
120 plasmid with Kip1p in close proximity to the spindle pole body is reminiscent of that of a CEN report
121 that the relocalization of Spc72p within the spindle pole body is the 'landmark' event in the pheromo
126 ulum excluded from the region containing the spindle-pole body, mitotic Golgi appeared to be disperse
127 mponents of the gamma-tubulin complex to non-spindle pole body MTOCs and physically interacts with th
132 n which the two newly synthesized meiosis II spindle pole bodies of MPC70/mpc70 strains lack Mpc70p.
134 wo new papers report the localisation at the spindle pole body of the Cdc14 released in early anaphas
135 e that TINA is specifically localized to the spindle pole bodies only during mitosis in a microtubule
136 by inactivating centromere attachment to the spindle pole body or changing the position of ribosomal
139 spindle assembly and elongation, interphase spindle pole body positioning, and epithelial cell reorg
140 minal region with similarity to the S. pombe spindle pole body protein Sad1 and to two predicted mamm
144 yces cerevisiae, the cytoplasmic face of the spindle pole body, referred to as the meiosis II outer p
148 netic nodes around the equator 10 min before spindle pole body separation (cell-cycle time, -10 min)
149 ng the earliest stages of mitosis to mediate spindle pole body separation and formation of a bipolar
150 More than 90 min prior to separation of the spindle pole bodies (SPB), the anillin-like protein (Mid
151 ast, spindle orientation begins with the old spindle pole body (SPB) (from the preceding cell cycle)
152 function is required for duplication of the spindle pole body (SPB) [12], the centrosome-equivalent
154 The asymmetric localization of Kar9p to one spindle pole body (SPB) and microtubule (MT) plus ends r
156 uter plaques (MOPs), form on each meiosis II spindle pole body (SPB) and serve as sites of membrane n
157 ing yeast polo kinase Cdc5p localizes to the spindle pole body (SPB) and to the bud-neck and plays mu
159 , while cytoplasmic microtubules vanish, the spindle pole body (SPB) assembles a long and stable mono
160 ein or tubulin revealed that the nucleus and spindle pole body (SPB) became oriented and tethered to
161 equired for linking telomeres to the meiotic spindle pole body (SPB) but not for attachment of telome
162 ecular architecture of the core of the yeast spindle pole body (SPB) by Bayesian integrative structur
164 11 mutation in the Schizosaccharomyces pombe spindle pole body (SPB) component Cut12 both suppresses
170 ual-specificity protein kinase essential for spindle pole body (SPB) duplication and required for the
171 he Mps1p protein kinase is critical for both spindle pole body (SPB) duplication and the mitotic spin
172 n essential protein kinase that has roles in spindle pole body (SPB) duplication and the spindle chec
173 ast MPS2 or the NDC1 gene leads to identical spindle pole body (SPB) duplication defects: The newly f
181 en for mutations that increase stress on the spindle pole body (SPB) in Saccharomyces cerevisiae.
184 (Saccharomyces cerevisiae) the multilayered spindle pole body (SPB) is embedded in the nuclear envel
185 duplication of the Saccharomyces cerevisiae spindle pole body (SPB) is required for formation of a b
192 isiae, nuclear pore complexes (NPCs) and the spindle pole body (SPB) must assemble into an intact nuc
196 Duplication of the Saccharomyces cerevisiae spindle pole body (SPB) once per cell cycle is essential
198 pecific component of the outer plaque of the spindle pole body (SPB) that is required for prospore me
199 triggers exit from mitosis, localize to the spindle pole body (SPB) that migrates into the daughter
200 ike Pcp1 regulates multiple functions of the spindle pole body (SPB) through recruiting two critical
203 Saccharomyces cerevisiae, Kar9p directs one spindle pole body (SPB) toward the incipient daughter ce
205 om poorly characterized interphase MTOCs and spindle pole body (SPB), and during late anaphase from t
206 e yeast centrosome-equivalent organelle, the spindle pole body (SPB), and it is involved in multiple
207 in spindle orientation, the migration of the spindle pole body (SPB), became actin-independent if it
208 ation of Sad1, a protein associated with the spindle pole body (SPB), in dot mutants showed an elevat
209 on of the budding yeast centrosome, called a spindle pole body (SPB), in late S-phase and G2/M, but t
210 normally localizes to only the bud-directed spindle pole body (SPB), Kar9p-L304P-3GFP was mislocaliz
211 ubule organizing centre (MTOC), known as the spindle pole body (SPB), organizes the nuclear and cytop
212 t on a component of the yeast centrosome, or spindle pole body (SPB), that is required for SPB duplic
213 c29p, which are three core components of the spindle pole body (SPB), the nuclear envelope-associated
214 , Sfi1p, localizes to the half-bridge of the spindle pole body (SPB), where Cdc31p is also localized.
215 the MEN-activating zone in the bud, and the spindle pole body (SPB), where the components of the MEN
216 ing yeast, microtubules are organized by the spindle pole body (SPB), which is embedded in the nuclea
217 le, the correct localization of Cdc7p to the spindle pole body (SPB), which is normally lost in spg1
218 y of nuclear-associated MTOCs, including the spindle pole body (SPB)--the centrosomal equivalent.
219 ation initiation network (SIN), an essential spindle pole body (SPB)-associated kinase cascade, which
220 late anaphase when spindle elongation brings spindle pole body (SPB)-localized Spg1 into proximity wi
229 anchors the septum initiation network to the spindle pole body (SPB, centrosome equivalent) to contro
230 The spindle position checkpoint (SPOC) is a spindle pole body (SPB, equivalent of mammalian centroso
231 or EAP30, Dot2, negatively regulates meiotic spindle pole body (SPB, the yeast equivalent of centroso
232 kinase Mps1 has well-characterized roles in spindle pole body (SPB, yeast centrosome equivalent) dup
233 is thought to be controlled by the daughter spindle-pole body (SPB) through a regulatory pathway nam
235 nters (MTOCs; mammalian centrosome and yeast spindle pole body [SPB]) nucleate more astral microtubul
237 lication of the yeast centrosome (called the spindle pole body, SPB) is thought to occur through a se
238 MEN is a signaling cascade that localizes to spindle pole bodies (SPBs) and activates the phosphatase
239 targeting the catalytic activity of Cdc5p to spindle pole bodies (SPBs) and cytokinetic neck-filament
240 ke proteins present in centrosomes and yeast spindle pole bodies (SPBs) and have essential functions
241 yces cerevisiae depends on a modification of spindle pole bodies (SPBs) at the onset of meiosis II th
242 spindles and found that only one of the two spindle pole bodies (SPBs) contains gamma-tubulin, altho
247 ning and electron microscopy showed that the spindle pole bodies (SPBs) either failed to complete nor
250 he outer and inner nuclear membranes and the spindle pole bodies (SPBs) fuse simultaneously and a thr
251 nt activation, S. pombe Dma1 concentrates at spindle pole bodies (SPBs) in an FHA-dependent manner an
252 (MTOCs), known as centrosomes in animals and spindle pole bodies (SPBs) in fungi, are important for t
257 lizes to the mother cell and associates with spindle pole bodies (SPBs) located in the mother cell to
258 e two nuclei, whereas dynein accumulating at spindle pole bodies (SPBs) may pull MTs nucleated from t
259 During fission yeast mitosis, the duplicated spindle pole bodies (SPBs) nucleate microtubule arrays t
260 on between nuclear pore complexes (NPCs) and spindle pole bodies (SPBs) revealed by our studies of th
261 enable nucleocytoplasmic transport, and the spindle pole bodies (SPBs) that mediate chromosome segre
262 elated proteins also bind to centrosomes and spindle pole bodies (SPBs) through proteins like the mam
264 ideally situated to inhibit MEN signaling at spindle pole bodies (SPBs) when anaphase spindle elongat
265 ation network) and measured their binding to spindle pole bodies (SPBs), the centrosome equivalent of
266 l unexpected structural modifications of the spindle pole bodies (SPBs), the yeast microtubule organi
269 Polo-like kinase and SIN activator, Plo1, to spindle pole bodies (SPBs), while at the same time prolo
275 ganisms such as fungi, centrosomes [known as spindle pole bodies (SPBs)] are essential for cell divis
276 Spg1, a Ras family GTPase that localizes to spindle-pole bodies (SPBs) throughout the cell cycle.
280 nucleus with centromeres clustering near the spindle pole body, telomeres clustering into foci at the
281 ras-related GTPase, Tem1, is located on the spindle pole body that enters the daughter cell and acti
282 ct intracellular pools: a stable pool at the spindle pole body that is depleted during cell cycle pro
283 gs, Mud is found associated with the central spindle pole body that lies between the two spindles of
284 regulator of mitotic exit, is present on the spindle pole body that migrates into the bud during S ph
285 ell fluorescence microscopy demonstrated the spindle pole body that segregated into the daughter cell
287 ona fide aggresome that colocalizes with the spindle pole body (the yeast centrosome) in a microtubul
292 alize Duo1p to intranuclear microtubules and spindle pole bodies to provide a previously unrecognized
293 s extending from centromeres adjacent to the spindle pole body to telomeres that abut the nuclear env
294 ype region, from its natural location at the spindle-pole body to the immediate vicinity of the nucle
295 Schizosaccharomyces pombe harbors MTOCs at spindle pole bodies, transient MTOCs in the division pla
296 1 normally accumulates (bud neck, nucleolus, spindle pole body) were not occupied by one PP1 variant.
297 ex to the half bridge, a substructure of the spindle pole body, where it organizes microtubules.
298 d-type strains, Mpc70p localizes to all four spindle pole bodies, whereas in MPC70/mpc70 strains Mpc7
299 required to recruit the MEN kinase Cdc15 to spindle pole bodies, which is both necessary and suffici
300 tion of Nak1 causes removal of Nak1 from the spindle pole bodies, which may both relieve Nak1 inhibit
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