ライフサイエンスコーパス: splay

1 , the fingers were placed in three levels of splay.

2 es formed around the ATPases BRAHMA (BRM) or SPLAYED.

3 s in both orientations when the fingers were splayed.

4 us faecalis Cas1-Cas2 selectively binds to a splayed 30-base-pair prespacer bearing 4-nucleotide 3' o

5 allel coiled coil whereas the other contains splayed alpha-helices.

6 aging in bipolar swimming in regions of pure splay and bend but switching to unipolar swimming in mix

7 es place on the area above electrodes due to splay and bend deformations of nematic liquid crystal al

8 defects provide large pinning energy, while splay and nanoparticles inhibit flux creep.

9 We calculated the energy of splay and tilt deformations necessary to avoid such hydr

10 o liquid crystalline deformations with bend, splay and twist; an analogy to cis/trans isomerism in or

11 rameters that supported both between-cluster splay and within-cluster synchrony.

12 he distal tyrosinated microtubules were less splayed and were closer to the leading edges of the grow

13 gene defect responsible for heterochromatic splaying and developmental abnormalities maps to chromos

14 Moreover, 85% of the N-termini are splayed, and the splayed N-terminus can capture transpor

15 of the molecule, but here the alpha-helices splay apart and are stabilized by the formation of a tai

16 At the C terminus, the helices splay apart and interact with a symmetry-related dimer i

17 uses the VERL molecules to lose cohesion and splay apart creating the hole.

18 cause the integrin alpha and beta chains to splay apart in the cytoplasm.

19 The N and C domains of DraTopIB are splayed apart in an "open" conformation, in which the su

20 T-loop and D-loop are splayed apart showing how A58, normally buried in tRNA,

21 next to the cleavage site on the 3' side is splayed apart.

22 ating that occurs by bundle crossing and the splaying apart of pore-lining helices commanding ion pas

23 their hand in two postures, with the fingers splayed (Apart posture) or pressed together (Together po

24 The U-A cleavage site adopts a splayed-apart conformation with the modelled 2'-O of U p

25 The U7-U8-U9OH 3' end, in a splayed-apart orientation, is sequestered within a basic

26 e C62-A63 step at the cleavage site adopts a splayed-apart orientation, with flexible C62 directed ou

27 antly in the alignment at the cleavage step (splayed-apart vs. base-stacked) and surrounding residues

28 c DNA binding protein with high affinity for splayed arm and 3'-flap DNAs.

29 ke HsGEN1, efficiently cleaves HJs, 5 flaps, splayed arms, and replication fork structures.

30 Lamellae splay as a consequence of space constraints related to s

31 ipid interface, to calculate lipid tilts and splays, as well as to fit the corresponding distribution

32 in an unusual conformation in which they are splayed at an oblique angle to each other, suggesting th

33 atin regulators: the well-studied BRAHMA and SPLAYED ATPases, as well as two closely related non-cano

34 but switching to unipolar swimming in mixed splay-bend regions.

35 Crystallographic analysis shows that splaying between the heteroaryl rings decreases while tw

36 he resultant strong suppression of twist and splay but not bend deformation in the columnar phase, ca

37 The peri-acridyl rings are slightly splayed but remain perfectly planar in all cases.

38 best results are obtained with a mixture of splayed columnar defects and random nanoparticles.

39 e on Fe and valency of S, and both exhibit a splayed configuration with respect to their three mu2S a

40 The contributions of splay conformation and internal dynamics of pyrenyl chai

41 l C-terminal extension of TetM with a unique splayed conformation of nucleotides A1492 and A1493 at t

42 ormations, can be rationalized by the saddle-splay contribution to the free energy.

43 tween the last stacked base and its adjacent splayed counterpart, and positioned within the groove of

44 The enhancement of saddle-splay curvature generation and relaxation of lipid compo

45 w that the requirement for generating saddle-splay curvature implies that a decrease in arginine cont

46 the range of lipid compositions where saddle-splay curvature was induced.

47 Hence, the splay deformation that scales linearly with the aggregat

48 marginally stable against spontaneous saddle splay deformation, which is incompatible with long-range

49 small twist elastic moduli relieve bend and splay deformations by introducing twist deformations.

50 ositional features, such as a sandy crevasse-splay deposit are found further away from the breach.

51 dimentary structures, and prevalent crevasse splay deposits.

52 al spatial relationships such as short ribs, splayed digits, and absent bones.

53 Unfolding of the linker begins with a splay distortion of proximal loops away from hydrophobic

54 unit distance (away from the inclusion), the splay-distortion component dominates close to the bilaye

55 nts: a compression-expansion component and a splay-distortion component, which includes the consequen

56 he compression-expansion energy but also the splay-distortion energy.

57 kness, the bilayer compression-expansion and splay-distortion moduli, and the inclusion radius (this

58 three contributions: compression-expansion, splay-distortion, and surface tension.

59 substrate was cleaved 90-fold faster than a splayed duplex substrate containing a single to double s

60 double strands to unpaired single strands ("splayed duplexes"), and DNA bulges in vitro.

61 sible for cleavage on Holliday junctions and splayed duplexes.

62 and render the intracellular vestibule less splayed during channel opening in the presence of ATP.

63 We conclude that the splayed dynamic distal ends of microtubules play a key r

64 e spontaneous twist, we determine the saddle-splay elastic constant for chromonic liquid crystals for

65 asuring M, the ratio of the Gaussian (saddle splay) elastic modulus to the bending elastic modulus of

66 Other fibers showed splayed ends or a lacy meshwork of surrounding protofibr

67 r toroidal droplets, we find that the saddle-splay energy screens the twisting energy, resulting in a

68 nclude narrow extensional troughs or graben, splay faults, and multiple low-relief terraces.

69 disordered, non-magnetic, ground state to a splayed ferromagnetic ground state.

70 eir engorgement with microtubules (MTs) that splay from the axon shaft.

71 her than that of the L(d) phase and a saddle-splay (Gauss) modulus difference with the Gauss modulus

72 ilayers is sensitive to kappa(m), the saddle splay (Gaussian curvature) elastic modulus of the lipid

73 his is the first determination of the saddle splay (Gaussian) modulus in a lipid system consisting on

74 niform, i.e., to be locally bouquet-like or "splayed." However, it is impossible to achieve splay of

75 ucing phospholipid protrusion and acyl-chain splay in the cholesterol-enriched rigid envelope.

76 de supporting evidence for the presence of a splay in the G(4)-C(9) base pair of the EcoRI binding si

77 ngth of the wild type, suggesting that it is splayed in its N-terminal half.

78 of cochlear hair cells are disorganized and splayed in mutant mice, with subsequent degeneration of

79 The significant decrease in splaying indicates enhanced pi-pi-attraction between the

80 s develop abnormally and remain immature and splayed into adulthood, corresponding with the early ons

81 , 12-13-nm-wide filaments and filaments that splayed into two 20-25-nm-wide components at one or both

82 The site of splaying involves a small group of destabilizing core re

83 a single sign requires defects and in the B7 splay is accommodated in the form of periodic splay stri

84 ying of the wHTH domains when Ile was bound; splaying is likely to account for the increased affinity

85 polarization to be locally bouquet-like or "splayed" is expressed.

86 rkably well-preserved specimen in an unusual splayed-limb and raised-head posture.

87 ng integrative soft-lithography on a backing splayed liquid-crystal elastomer (LCE).

88 ymers increased the amount of induced saddle-splay membrane curvature and broadened the range of lipi

89 A mechanism of action based on saddle-splay membrane curvature generation is broadly enabling,

90 Importantly, saddle-splay membrane curvature generation places constraints o

91 inity eribulin binding sites, most likely at splayed microtubule ends.

92 tion occurs, wherein it conforms to a unique splay-minimizing configuration.

93 structure uniquely presented by the RPo: the splayed minor groove at the double-stranded/single-stran

94 Surprisingly, the splay mode between clusters could enforce synchrony on s

95 teria were also developed and tested for the splay mode in which neurons fire sequentially.

96 otorious in this regard are the polarization splay modulated (B7) phases, in which the symmetry-requi

97 c field which originates in the periodically splay-modulated bulk of the LC rather than by surface st

98 extended to account for nonvanishing saddle splay modulus within lipid monolayers and perturbations

99 elative increase of the material's bend over splay modulus.

100 cusp (prolapse, restriction) and commissure (splaying) morphology; root pathology was less important.

101 r, 85% of the N-termini are splayed, and the splayed N-terminus can capture transport vesicles in vit

102 ranes: defensins selectively generate saddle-splay ("negative Gaussian") membrane curvature in model

103 es by generating topologically active saddle-splay ("negative Gaussian") membrane curvature through m

104 layed." However, it is impossible to achieve splay of a preferred sign everywhere in space unless app

105 Filling space with splay of a single sign requires defects and in the B7 sp

106 ithin the optic tract region, meandering and splaying of axons in the optic tectum, and the induction

107 addition to drc-mutant axonemes resulted in splaying of doublets in the distal region, followed by o

108 ( approximately 1.3 degrees ) but systematic splaying of individual lamellae in the film.

109 ated to passing of the hydration barrier and splaying of lipids to eventually enter either the fully

110 In growth cones and at axon branch points, splaying of looped or bundled microtubules is accompanie

111 is proposed based on the structure, whereby splaying of the bottom of the pore is possible without r

112 type channels, the R165A mutation results in splaying of the cytoplasmic domains away from the centra

113 N-terminal fraying and C-terminal splaying of the helices, as well as the asymmetry and he

114 ffer in their packing interface, causing the splaying of the two sheets in CarG.

115 CodY-Ile derived from the tetramers showed a splaying of the wHTH domains when Ile was bound; splayin

116 m the distributions of microscopic tilts and splays of the lipid components.

117 in after considering the influence of saddle splay on the elastic free energy.

118 In a bent configuration the inner helices splay open creating a wide (12 A) entryway.

119 Bundles abandon a compact form and splay open just as they reach a major blood vessel.

120 ferating Cell Nuclear Antigen (PCNA) must be splayed open at one of the subunit-subunit interfaces by

121 The small size and splayed open configuration of the E-F hairpin facilitate

122 clusion for ions in the closed state and are splayed open on activation.

123 extracellular-half of the pore-lining M2 is splayed open, reminiscent of the open conformation, whil

124 dimeric HIP1 crystal structure is partially splayed open.

125 o DNA-binding domains of LacI are capable of splaying open about the tetramerization domain into an e

126 mpact bundle over hypothalamus, dramatically splay out over thalamus, and circumvent epithalamus as t

127 ch is equivalent to beta-strand 1 in LC8, is splayed out and binds to a crystallographic dimer as an

128 The heads are splayed out and there is even more heterogeneity in the

129 n the current structure, which is has an NTD splayed out with respect to previous structures, and oth

130 Fibrillin-1 filaments splayed out, extending beyond the width of the periodic

131 For this to occur, the highly dynamic, splayed-out microtubule (MT) arrays characteristic of th

132 enylvinyl moiety in the TT isomer of 2Q gets splayed over the helical scaffold such that it is fraugh

133 ion as a replacement of energetically costly splay packing of the aggregates within the curved bipola

134 ive extrapolated-motion protocol to pack the splayed peripheral TM1 and TM2 transmembrane helices alo

135 lly elongated, are frequently bent, and have splayed poles by prometaphase.

136 ring, low posture and clonus and potentiated splayed postural effects.

137 chattering, tremor/trembling, head weaving, splayed posture, clonus and wet dog shakes.

138 polar smectic liquid crystals in which local splay prevails in the form of periodic supermolecular-sc

139 Depleted of nucleotide, NSF converts to a "splayed" protease-sensitive conformation that reveals it

140 that Tctp deficiency results in stunted and splayed retinotectal projections that fail to innervate

141 membrane leafs to display a heterogeneity in splay rigidities.

142 namic assembly and disassembly, bundling and splaying, severing, and rapid transport as well as integ

143 on of both Kid and NuMA in stark contrast to splayed spindle poles observed after perturbation of NuM

144 ons for the nine Usher-associated genes have splayed stereocilia, and some show delayed maturation of

145 play is accommodated in the form of periodic splay stripes spaced by defects and coupled to smectic l

146 t the SWI2/SNF2 chromatin-remodeling ATPases SPLAYED (SYD) and BRAHMA (BRM) are redundantly required

147 The SPLAYED (SYD) gene product acts with LFY to regulate sho

148 ly important target of the SNF2-class ATPase SPLAYED (SYD) in the shoot apical meristem of Arabidopsi

149 The SNF2-like chromatin-remodeling ATPase SPLAYED (SYD) was identified as a co-activator of floral

150 s thaliana SWI/SNF ATPases, BRAHMA (BRM) and SPLAYED (SYD), are viable, facilitating investigation of

151 By contrast, a null allele of SPLAYED (SYD), the closest homolog of AtBRM in Arabidops

152 ncluding thickness compression, tension, and splay terms to describe the membrane deformation.

153 g surface spanning the length of the DNA and splays the ends of the protospacer to allow each termina

154 s a hinge motion at a conserved glycine that splays the inner-pore helices wide open.

155 duced in number and were frequently bulbous, splayed, tightly clustered and enlarged.

156 their poles failed to converge, as MTs were splayed to discrete positions rendering deformed arrays.

157 the external milieu by means of gaps between splayed transmembrane helices.

158 l formation occurs when cracked or partially splayed trimers bind and penetrate the bilayer.

159 helixes within each S100beta subunit form a splayed-type four-helix bundle (four perpendicular helix

160 ngence arising from crystallite twisting and splaying under confinement.

161 28-(127-588) comprises two RecA-like domains splayed widely apart.

162 bic fissure in bilayers for stalk formation, splay within the expanding hemifusion diaphragm, and fis

163 The splayed Y junction defines a class III substrate having