ライフサイエンスコーパス: spontaneous activity

1 ic penumbra (i.e. isoelectric cortex with no spontaneous activity).

2 rmal neuritogenesis and void of synchronized spontaneous activity.

3 used a dramatic loss of spatial coherence of spontaneous activity.

4 role of calcium signaling in regulating GoC spontaneous activity.

5 twork inhibition, followed by an increase in spontaneous activity.

6 rons (CINs) based on statistical measures of spontaneous activity.

7 esentation and by controlling the pattern of spontaneous activity.

8 anthanum alone was a potent inhibitor of the spontaneous activity.

9 cid, and carbenoxolone significantly blocked spontaneous activity.

10 rrelation index to investigate the nature of spontaneous activity.

11 rd 'window current' at rest, contributing to spontaneous activity.

12 cortex neurons displayed a 26% reduction in spontaneous activity.

13 of awake mice during visual stimulation and spontaneous activity.

14 This phenomenon was modulated by daily spontaneous activity.

15 tracking system in near-darkness to monitor spontaneous activity.

16 ained across the cortex by locally-generated spontaneous activity.

17 ortex displays rich, coordinated patterns of spontaneous activity.

18 e to these interregional interactions during spontaneous activity.

19 eased anterior piriform cortical single-unit spontaneous activity.

20 nectivity was estimated from correlations of spontaneous activity.

21 erience on the systems-level organization of spontaneous activity.

22 ar membrane potential and thus reduces their spontaneous activity.

23 creased expression of Nav1.7 associated with spontaneous activity.

24 ty or to inhibit odour-evoked suppression of spontaneous activity.

25 omote survival of young neurons by promoting spontaneous activity.

26 Both ZD7288 and DK-AH 269 reduced spontaneous activity.

27 ists and theorists in analyzing and modeling spontaneous activity.

28 ponsiveness, consistently exhibited elevated spontaneous activity.

29 the generation, maintenance, and richness of spontaneous activity.

30 local cortical microcircuits to decorrelate spontaneous activity.

31 help to enlighten the mechanisms underlying spontaneous activity.

32 vascular regulation for both stimulation and spontaneous activity.

33 46 prolongs evoked release, without altering spontaneous activity.

34 ity generated by BCs rather than to initiate spontaneous activity.

35 detection of signals despite the presence of spontaneous activity?

36 Dabigatran-treated PVs had slower spontaneous activity (1.1+/-0.1 Hz; n=10; P=0.0001 versu

37 ntly increased visually evoked responses and spontaneous activity, a decreased signal-to-noise ratio

38 ow that copper is an endogenous modulator of spontaneous activity, a property of functional neural ci

39 represent the current state and change their spontaneous activity accordingly.

40 ell activity elevates the synchronization of spontaneous activity across a broad frequency range and

41 t auditory cortical areas, and then recorded spontaneous activity across this defined network.

42 mechanisms could interact extensively, with spontaneous activity affecting the expression and functi

43 raises the possibility that training ongoing spontaneous activity alone might be sufficient for enhan

44 h early electrophysiological signs of muscle spontaneous activities and histological signs of muscle

45 mined by field potential recordings revealed spontaneous activities and pathological high-frequency o

46 orm discharges; (ii) prolonged depression of spontaneous activity and (iii) occurrence in temporal cl

47 We find that SynII(-) neurons have increased spontaneous activity and a reduced threshold for the ind

48 efore, elucidating conductances that mediate spontaneous activity and changes of firing pattern in th

49 We show that elevated and noisy spontaneous activity and contrast-dependent noisy spikin

50 alized calcium signals, yet reduces afferent spontaneous activity and disrupts the timing of stimulus

51 Spontaneous activity and energy expenditure did not diff

52 physiological consequences are a decrease in spontaneous activity and excessive excitation, likely to

53 These results indicate an increased spontaneous activity and faster deactivation of PDE6C co

54 g signal detection, norepinephrine decreased spontaneous activity and firing during stimuli, yet it s

55 -not inhibited by HNCS-and characterized for spontaneous activity and for neuronal discharges evoked

56 nificantly elevated firing rates both during spontaneous activity and in response to whisker deflecti

57 Tg(sm/p22phox) mice displayed impaired spontaneous activity and increased mitochondrial ROS pro

58 factory sensory neurons have greatly reduced spontaneous activity and lack odour-evoked responses.

59 ervations indicate that there are changes in spontaneous activity and light-evoked responses in RGCs

60 ing in the brainstem inhibit inner hair cell spontaneous activity and may further refine maturation.

61 osensory inputs to the DCN that can modulate spontaneous activity and might mediate the somatic-audit

62 n as the network state) that include ongoing spontaneous activity and neuromodulation.

63 and blunted the impact of D2R activation on spontaneous activity and neuronal excitability.

64 ator norepinephrine modulates olfactory bulb spontaneous activity and odor responses so as to generat

65 spreading depolarizations with depression of spontaneous activity and only 26% of patients (6/23) who

66 time course that matches the development of spontaneous activity and pain hypersensitivity in animal

67 AIS and resulted in loss of Purkinje neuron spontaneous activity and pinceau disorganization.

68 y, OFF-transient RGCs displayed decreases in spontaneous activity and receptive field size.

69 stibular nuclear complex and comparing their spontaneous activity and sensory responses during defaul

70 MUA) from macaque V1, S1, and A1 during both spontaneous activity and sensory stimulation.

71 neural responses are highly variable during spontaneous activity and sensory stimulation.

72 synaptic activity and hence are sensitive to spontaneous activity and spurious correlations.

73 rception depends on the interplay of ongoing spontaneous activity and stimulus-evoked activity in sen

74 ient to maintain the intrinsically generated spontaneous activity and that patterned spontaneous acti

75 nhibition ratio impacts the structure of the spontaneous activity and the information transmission at

76 excitability of NPY neurons to modulate the spontaneous activity and the integration of synaptic inp

77 rams to identify groups of CINs with similar spontaneous activity and then asked how these groups map

78 Finally, alcohol failed to enhance RMTg spontaneous activity and to prolong RMTg-induced silenci

79 ns are highly irregular both during ongoing, spontaneous activity and when driven at high firing rate

80 lenged skin exhibited a greater incidence of spontaneous activity and/or abnormal after-discharges in

81 rols (n=20) on offspring energy expenditure, spontaneous activity, and body composition at 3, 6, and

82 ry responsiveness yet had minimal impacts on spontaneous activity, and cck expression induced the opp

83 obutyric acid (GABA) signaling, limits early spontaneous activity, and constrains dendritic growth.

84 atively unusual approach: the observation of spontaneous activity, and correlated patterns in spontan

85 ocomotion had two main effects: it increased spontaneous activity, and it weakened the suppressive si

86 e injury influenced the functional rewiring, spontaneous activity, and network plasticity following i

87 , we tracked receptive field reorganization, spontaneous activity, and response gain from individual

88 r maximal diastolic potentials, exhibited no spontaneous activity, and showed a gradual decrease in a

89 In the auditory system, rhythmic bursts of spontaneous activity are generated in cochlear hair cell

90 ation shows that these changes in evoked and spontaneous activity are important for sound perception.

91 ay are understanding how patterns of ongoing spontaneous activity are modified by task performance an

92 has revealed that infraslow fluctuations in spontaneous activity are organized into stereotyped spat

93 and the spatial extent and frequency of the spontaneous activity are tightly regulated by stage.

94 s are electrophysiologically mature, display spontaneous activity, are surrounded by nonreactive astr

95 t common physiologic mechanisms may underlie spontaneous activity as imaged with fMRI in humans and s

96 2-electrode array (60 mum spacing) to record spontaneous activity at 20 kHz from up to 500 neurons si

97 nd the induced events propagate similarly to spontaneous activity at earlier stages, though without i

98 Spiral ganglion neurons exhibit spontaneous activity at least by E14 and are able to dri

99 In separate sessions, we then observed that spontaneous activity at the same sites exhibited spatial

100 vidence that the precise temporal pattern of spontaneous activity before hearing onset is crucial for

101 In sensory systems, patterned spontaneous activity before the onset of sensation is th

102 ound rhythmic patterns of global synchronous spontaneous activity between neurons, which depends on v

103 By contrast, synchronous spontaneous activity between non-neuronal cells is media

104 hotoactivation of VALopA not only suppresses spontaneous activity but also alters the maturation of t

105 play a significant role in the generation of spontaneous activity but are critical for the transition

106 play a significant role in the generation of spontaneous activity but are critical for the transition

107 e clustering, on the other hand, facilitated spontaneous activity but led to degenerating patterns of

108 cortex is characterized in vivo by irregular spontaneous activity, but how this ongoing dynamics affe

109 Many developing circuits exhibit spontaneous activity, but its role in the synaptic organ

110 re the onset of experience must be driven by spontaneous activity, but the origin and nature of activ

111 Traveling waves are present also during spontaneous activity, but they can be greatly reduced by

112 or nuclei involves a novel interplay between spontaneous activity, cadherin expression and gap juncti

113 During sequences of spontaneous activity, calcium signals recorded at each l

114 terspike intervals (ISIs) of cat ANFs during spontaneous activity can be modeled as resulting from re

115 ule cell layer, it is not known whether this spontaneous activity can be modulated in a long-term man

116 Studies of patterned spontaneous activity can elucidate how the organization

117 These apparent connections revealed during spontaneous activity coactivation by GCaMP3 were confirm

118 This regulation has marked effects on spontaneous activity, converting the predominant mode of

119 that co-time-tuned neurons exhibit enhanced spontaneous activity correlations that increase just pri

120 ler temperatures, coupled with a decrease in spontaneous activity, could also allow individuals to in

121 ecular guidance cues expressed in gradients; spontaneous activity-dependent axonal and dendritic remo

122 c effects contributed 3% and 8% of the SD of spontaneous activity-dependent GCaMP3 fluorescence when

123 antial evidence that altering the pattern of spontaneous activity disrupts refinement, but the mechan

124 Spontaneous activity driven by "pacemaker" neurons, defi

125 Spontaneous activity drives early mammalian circuit deve

126 mice engineered to have very little afferent spontaneous activity due to the overexpression of the in

127 By correlating spontaneous activity during "resting states" [1], studie

128 neural circuits are established by patterned spontaneous activity during development.

129 In the human brain, spontaneous activity during resting state consists of ra

130 animate target significantly correlated with spontaneous activity during the resting state indexed by

131 mesoscale architectures in the regulation of spontaneous activity dynamics.SIGNIFICANCE STATEMENT Com

132 els in the RTN are essential determinants of spontaneous activity ex vivo, and downstream effectors f

133 Results show (1) a sequential increase in spontaneous activities, first in the injured TG neurons

134 They often served as broker of spontaneous activity flow, confirming that hub nodes and

135 rbachol had a transient excitatory effect on spontaneous activity followed by a rapid weakening of ac

136 activity, converting the predominant mode of spontaneous activity from bursts to regular spiking.

137 stic startle to assess tinnitus, we recorded spontaneous activity from fusiform cells, the principle

138 ur experiments argue for the dissociation of spontaneous activity from hard-wired developmental progr

139 ssociable: neuropeptide expression uncoupled spontaneous activity from sensory responsiveness, and un

140 We record spontaneous activity from up to 150 neurons in the hippo

141 ergic agonist carbachol normally decorrelate spontaneous activity generated by deep layer prefrontal

142 neurons simultaneously to study patterns of spontaneous activity generated by these circuits under n

143 actions between cadherins, gap junctions and spontaneous activity governs neuron assembly, presaging

144 r by comparing peak/trough firing rates with spontaneous activity (half-cycle thresholds).

145 While spontaneous activity has been shown to instruct map form

146 In human resting-state fMRI, spontaneous activity has been understood predominantly i

147 ce are effective mechanisms to desynchronize spontaneous activity in a spatiotemporal manner, while a

148 um imaging indicates that serotonin inhibits spontaneous activity in abdominal LK neurons.

149 ekplexia mutations, Q226E and V280M, induced spontaneous activity in alpha1 glycine receptors.

150 rained human participants to control ongoing spontaneous activity in circumscribed regions of retinot

151 Ongoing spontaneous activity in cortical circuits defines cortic

152 nnel alters the spatiotemporal properties of spontaneous activity in developing hippocampal and retin

153 Such spontaneous activity in developing spinal cord contribut

154 ly knocking down Nav1.8 after SCI suppressed spontaneous activity in dissociated dorsal root ganglion

155 poral resolution, BOLD signal and LFP during spontaneous activity in early visual cortices of anesthe

156 vestigate how the mesoscale structure shapes spontaneous activity in generic networks of rat cortical

157 rk reveals an instructive role for patterned spontaneous activity in guiding the functional developme

158 ls were used to quantify total body area and spontaneous activity in live embryos.

159 er and persisting spatiotemporal patterns of spontaneous activity in neuronal networks with neuron cl

160 velopmental maturation of normal patterns of spontaneous activity in olfactory sensory neurons, and w

161 interactions in the antennal lobe, and that spontaneous activity in ORNs tonically depolarizes the r

162 l excitation in ZIv and caused inhibition of spontaneous activity in POm.

163 hesis by using two-photon calcium imaging of spontaneous activity in populations of retinal neurons a

164 in R-fMRI signals consistent with a role of spontaneous activity in representing task-relevant infor

165 n-As, activity-dependent processes driven by spontaneous activity in RGCs, and different forms of axo

166 Here we demonstrate a different role for spontaneous activity in sensory cortex: gating of sensor

167 Spontaneous activity in the absence of external input, i

168 n benzoate-both potent avermectins-abolished spontaneous activity in the absence of gross malformatio

169 indings provide new insight into the ongoing spontaneous activity in the awake and anesthetized state

170 In the absence of sensory stimuli, spontaneous activity in the brain has been shown to exhi

171 First, elevated spontaneous activity in the DCN is correlated with perip

172 Spontaneous activity in the developing brain contributes

173 extraretinal opsins early on, at a time when spontaneous activity in the developing CNS plays a role

174 Correlated spontaneous activity in the developing nervous system is

175 test this hypothesis, we recorded multiunit spontaneous activity in the fusiform soma layer (FSL) of

176 sts, which reduce, but do not eliminate, the spontaneous activity in the IO.

177 Trial self-initiation decreases the rate of spontaneous activity in the majority of recorded cells.

178 ging, we studied spatio-temporal patterns of spontaneous activity in the optic tectum of Xenopus tadp

179 nges in spiking around an elevated baseline, spontaneous activity in the piriform cortex extends the

180 al both in vivo and in vitro, revealing that spontaneous activity in the prehearing cochlea promotes

181 onsmokers, only a few studies assessed brain spontaneous activity in the resting state in chronic smo

182 t origins - local intracortical circuits and spontaneous activity in the retina.

183 Spontaneous activity in the sensory periphery drives inf

184 mework, based on predictive coding, in which spontaneous activity in the subcortical auditory pathway

185 Temporary circuits amplify spontaneous activity in the visual system of neonatal ra

186 GABAA receptors, whereas gabazine suppressed spontaneous activity in these receptors.

187 hat shape daily patterns of light-evoked and spontaneous activity in this network of hypothalamic cel

188 morphology and architecture with respect to spontaneous activity in this population, we visualized t

189 demonstrate that cell-intrinsic blockade of spontaneous activity in vivo does not affect neuronal id

190 d to affect HR responses to isoproterenol or spontaneous activity in vivo or in SANC.

191 citatory postsynaptic currents and increased spontaneous activity in vivo.

192 critical contributor to that process is the spontaneous activity - in the form of limb twitches - th

193 taneous activity, and correlated patterns in spontaneous activity, in the "resting" brain.

194 eases whole-body oxygen consumption, reduces spontaneous activity, increases adiposity and glucose in

195 To understand the source of the neuronal spontaneous activity, input to the tectum was systematic

196 Patterned spontaneous activity is a hallmark of developing sensory

197 One intriguing aspect of spontaneous activity is an apparent nonstationarity, or

198 easingly, functional connectivity mapping of spontaneous activity is being used to reveal the organiz

199 Noisy or spontaneous activity is common in neural systems and pos

200 fers from the mammalian visual system, whose spontaneous activity is controlled by retinal waves.

201 maging (fMRI) in the resting state (R-fMRI), spontaneous activity is correlated between brain regions

202 However, intrinsic spontaneous activity is critical for axon branching and

203 Thus, spontaneous activity is driven primarily by activation o

204 Spontaneous activity is found in many regions of the dev

205 EphA3/+) mice, demonstrating that correlated spontaneous activity is required for map heterogeneity.

206 However, this spontaneous activity is suppressed by coupling to an ove

207 A prominent type of such spontaneous activity is the alpha rhythm, which influenc

208 Spontaneous activity is thought to regulate synaptogenes

209 ergic antagonists are known to abolish early spontaneous activity, it has long been assumed that spin

210 Thus, whether spontaneous activity itself promotes synaptogenesis or p

211 erties of conductances that underlie regular spontaneous activity, less is known about those that und

212 We found that spontaneous activity long observed in the secondary proj

213 nges in this activity, two key components of spontaneous activity maturation were revealed: (1) spind

214 a-fiber neurons (maximally by 19%) and basal spontaneous activity (maximally by 33%) in the rat trige

215 In both areas, spontaneous activity (measured during fixation while vie

216 in AIA mice exhibited a greater incidence of spontaneous activity, mechanically evoked after-discharg

217 depolarizations occurred with depression of spontaneous activity (median 2 min 10 s; P<0.001).

218 We conclude by describing spontaneous activity models in other systems and suggest

219 As a result of depression during high spontaneous activity, more cartwheel interneurons were r

220 Spontaneous activity observed with resting-state fMRI is

221 te the retinal outputs--the light-evoked and spontaneous activities of individual ganglion cells--is

222 neural encoding of temporal sequences in the spontaneous activity of brain tissue and suggest a local

223 nicotinic receptors, (2) independent on the spontaneous activity of cholinergic interneurons, and (3

224 ere is, in fact, a natural clustering of the spontaneous activity of CINs into six groups but that th

225 In the auditory system, spontaneous activity of cochlear inner hair cells (IHCs)

226 The spontaneous activity of excitatory-inhibitory neuron pai

227 The extent of inhibition depends on both spontaneous activity of GoCs and the excitatory synaptic

228 tic deletion of TMEM16A markedly reduces the spontaneous activity of IHCs and spiral ganglion neurons

229 ty to respond, latency, and preference), and spontaneous activity of individual L2/3 pyramidal neuron

230 C, we have visualized Ca(2+) dynamics during spontaneous activity of neuronal cultures as confirmed b

231 ed ZIP, induced a dose-dependent increase in spontaneous activity of neurons in dissociated cultures

232 ed ZIP, induced a dose-dependent increase in spontaneous activity of neurons in dissociated cultures

233 Circuit-specific recordings reveal that spontaneous activity of nucleus accumbens-projecting VTA

234 We also find that anxiety suppresses spontaneous activity of PFC neurons, and weakens encodin

235 The ionic mechanisms that support spontaneous activity of RTN neurons are unknown.

236 The spontaneous activity of serotonergic neurons correlates

237 of presynaptic GABAb receptors gated by the spontaneous activity of somatostatin-expressing (Sst) in

238 In addition, the spontaneous activity of STN neurons in R6/2 mice was red

239 nction inhibitor carbenoxolone increases the spontaneous activity of suprachiasmatic nucleus neurones

240 role for the autonomic nervous system to the spontaneous activity of the brain during "rest."

241 The spontaneous activity of the brain shows different featur

242 ing (afferent) auditory system by inhibiting spontaneous activity of the IHCs.

243 we found that the strength of correlation in spontaneous activity of the individual cells varied as a

244 KEY POINTS: Spontaneous activity of the sensory inner hair cells sha

245 " (sensory evoked response) and the "noise" (spontaneous activity) of cortical responses.

246 nted on nogo trials, permitting us to assess spontaneous activity on trials in which a signal could h

247 evelop without requiring precise patterns of spontaneous activity or molecular guidance.

248 ely small changes in key parameters, such as spontaneous activity or strength of the light manipulati

249 o any self-organising process facilitated by spontaneous activity or training.

250 rtical network recurrent circuitry generates spontaneous activity organized into Up (active) and Down

251 ut noise in the olfactory system: Where does spontaneous activity originate?

252 Interestingly, phase shifts observed during spontaneous activity paralleled latency differences for

253 ons contribute to retinal waves, we compared spontaneous activity patterns using calcium imaging, who

254 -dependent correlation in sensory-driven and spontaneous activity patterns.

255 hich tune weak network connectivity based on spontaneous activity patterns: a Hebbian model, where co

256 oposed that genetically encoded programs and spontaneous activity play complementary but independent

257 Our data suggest that spontaneous activity plays a critical role not only in t

258 In the developing mouse hindbrain, spontaneous activity propagates widely and the waves can

259 tion, mutations, and drugs on ATP-driven and spontaneous activity, providing insights for understandi

260 system alone had little effect on patterned spontaneous activity, removing input from both systems d

261 During sleep, spontaneous activity renormalizes net synaptic strength

262 sts measuring traits, such as body position, spontaneous activity, respiration, tremors, body tone, a

263 ated spontaneous activity and that patterned spontaneous activity results from input from multisensor

264 Persistent spontaneous activity (SA) generated in the cell bodies o

265 st in part by long-lasting sensitization and spontaneous activity (SA) in peripheral branches of prim

266 mM) significantly decreased the amplitude of spontaneous activity (SA) in SCI bladder muscle strips.

267 Using live imaging, we discover that spontaneous activity selectively regulates the rate of s

268 is also enhanced by the occurrence of random spontaneous activity, such as is normally observed in th

269 nships can be modulated by the properties of spontaneous activity, suggesting its instructive role fo

270 Abstract Spontaneous activity supports developmental processes in

271 or, and another approximately 15% have their spontaneous activity suppressed.

272 acute tests, whereas 5g was active only in a spontaneous activity test.

273 The human brain shows spontaneous activity that is strongly correlated across

274 In all stimulus conditions and during spontaneous activity, the average LFP power at frequenci

275 ccuracy is observed when, in the presence of spontaneous activity, the levels of potassium conductanc

276 During spontaneous activity, the reduction of correlation accom

277 This suggests that specific patterns of spontaneous activity throughout the developing brain are

278 We used magnetoencephalography recordings of spontaneous activity to characterize whole-brain functio

279 le is known about the capacity for patterned spontaneous activity to drive the maturation of receptiv

280 g active (or REM) sleep, brainstem-generated spontaneous activity triggers hundreds of thousands of s

281 ons showed both stimulus-evoked activity and spontaneous activity under physiological parameters.

282 in vivo and in vitro population measures of spontaneous activity, using the LFP, EEG, MEG or fMRI su

283 -sensitive potassium (KATP) channels exhibit spontaneous activity via a phosphatidylinositol-4,5-bisp

284 Spontaneous activity was detected in 31% of silent nocic

285 reased stepwise to suprathreshold levels and spontaneous activity was enhanced.

286 Electromyographically, spontaneous activity was found in 10 of 14 patients and

287 At the network level, spontaneous activity was less synchronized over cortical

288 A concurrent increase in spontaneous activity was observed.

289 The spike count, CV(2), and m-FF of spontaneous activity were also elevated in amblyopic neu

290 The beat rate time series of the spontaneous activity were examined in terms of their pow

291 howed temporally simple responses and little spontaneous activity, whereas MT cells were spontaneousl

292 Relative to spontaneous activity (which increased with engagement),

293 ycles may provide insight into mechanisms of spontaneous activity, which recently has been shown to c

294 Retinal waves are correlated bursts of spontaneous activity whose spatiotemporal patterns are c

295 mammalian cerebellum express high-frequency spontaneous activity with average spike rates between 30

296 d a 384-well-based HCS assay that quantifies spontaneous activity within single zebrafish embryos aft

297 ared mice suggesting a differential role for spontaneous activity within thalamocortical and intracor

298 d signals, but also completely shut down the spontaneous activity within the IO, which affects the re

299 patterns were also present in recordings of spontaneous activity without any sensory stimulation and

300 mice) altered the temporal fine structure of spontaneous activity without changing activity levels.