ライフサイエンスコーパス: spontaneous firing

1 shed from background inhibition arising from spontaneous firing.

2 trains of synaptic inhibition that interrupt spontaneous firing.

3 that SNr neurons lacking NALCN have impaired spontaneous firing.

4 enlarged mGluR1/5 responses and accelerated spontaneous firing.

5 s were suprathreshold, generating repetitive spontaneous firing.

6 l, which increased RS and the probability of spontaneous firing.

7 rmining the ionic conductances that underlie spontaneous firing.

8 (135/171 or 79%) of these MRF neurons lacked spontaneous firing.

9 mV, and this current is sufficient to drive spontaneous firing.

10 s with an intrinsic propensity for rhythmic, spontaneous firing.

11 y 18 spikes/sec, compared with 16 spikes/sec spontaneous firing.

12 zing afterpotential is sufficient to trigger spontaneous firing.

13 but had a scarce effect on the frequency of spontaneous firing.

14 fane eliminated evoked firing and suppressed spontaneous firing.

15 timulus-evoked firing was affected more than spontaneous firing.

16 nt-threshold, increased firing-frequency and spontaneous firing.

17 tion, induces a long-lasting increase in GoC spontaneous firing.

18 ted by dopamine to a greater extent than was spontaneous firing.

19 to suprathreshold stimulation and increased spontaneous firing.

20 id not drive spike responses, but suppressed spontaneous firings.

21 ectively, resulted in significant changes in spontaneous firings.

22 During spontaneous firing, a rise in free cytoplasmic calcium w

23 nhibited LTSIs, reducing or abolishing their spontaneous firing activity and causing membrane hyperpo

24 esponsiveness to peripheral stimuli, reduced spontaneous firing activity from WDR neurons, and improv

25 e the growth factor positively regulates the spontaneous firing activity of both NAc- and PFC-project

26 The overall spontaneous firing activity of Purkinje cells was increa

27 Reducing spontaneous firing activity with 10 nM tetrodotoxin (TTX

28 in animals with tinnitus exhibited enhanced spontaneous firing, altered burst properties and increas

29 onist, WIN 55,212-2, significantly increased spontaneous firing and bursting rates of VTA DA neurons,

30 NE iontophoresis inhibited spontaneous firing and decreased the responsiveness of B

31 Both spontaneous firing and evoked bursts of spikes were dimi

32 M) cells, noradrenergic activation decreases spontaneous firing and focuses receptive fields.

33 in adult Fgf14(-/-) Purkinje neurons rescues spontaneous firing and improves motor performance.

34 These results held both for spontaneous firing and in the presence of independent vi

35 Ephedrine (100-1000 microM) slowed spontaneous firing and produced a modest concentration-d

36 Arousal suppressed spontaneous firing and strongly altered the temporal pat

37 and proximal dendrites of STN neurons during spontaneous firing and their accumulation during driven

38 ivates the superior colliculus by increasing spontaneous firing and, in some cells, whisker-evoked re

39 Hyperpolarization to -85 mV prevented spontaneous firing, and brief depolarization then induce

40 ial of dorsal root ganglion neurons, enhance spontaneous firing, and increase evoked firing of these

41 tured on MEAs displayed a rich repertoire of spontaneous firing, and Shank3 deletion led to reduced f

42 but the ionic mechanisms responsible for the spontaneous firing are apparently different.

43 zing shift in resting potential and enhanced spontaneous firing are due to persistent activity of var

44 ls, in the absence of glucose, sustained SNr spontaneous firing at basal rates, but glycolysis may st

45 e of applied odors, piriform neurons exhibit spontaneous firing at mean rates that vary systematicall

46 aneous VP neuronal activity; DAMGO inhibited spontaneous firing but potentiated AMG-evoked glutamater

47 cific PDE3 inhibitor, milrinone, accelerated spontaneous firing by approximately 47% (effects of othe

48 ity and trigger action potentials or inhibit spontaneous firing by depolarization block.

49 nin effect on resting membrane potential and spontaneous firing; co-activation of GABA(B) receptors i

50 n the PFC caused a simultaneous reduction in spontaneous firing (consistent with extracellular in viv

51 Both evoked and spontaneous firing could be inhibited by iontophoresis o

52 ld while profoundly suppressing 4-AP-induced spontaneous firing, demonstrating a functional synergy b

53 During quiet wakefulness, the brain produces spontaneous firing events that can spread over large are

54 onductance, may contribute to the changes in spontaneous firings exhibited by retinal ganglion cells

55 Similarly, isoprenaline increased the spontaneous firing frequency by an effect exclusively on

56 Circadian changes in membrane potential and spontaneous firing frequency have been observed in micro

57 The spontaneous firing frequency lay in the middle of the dy

58 luster of differentiation 4 (CD4)), enhanced spontaneous firing frequency.

59 We find that spontaneous firing generates tonic Ca signals in both so

60 During spontaneous firing, glycine release was decreased due to

61 Such spontaneous firing has a structure that reflects the coo

62 d sensory neuron excitability, manifested as spontaneous firing, hyper-responsiveness to stimulation,

63 Increased spontaneous firing (hyperactivity) is induced in fusifor

64 roduced a small depolarization and increased spontaneous firing in 10 of 30 retrogradely labelled gas

65 y and indiscriminately increased the rate of spontaneous firing in all MS/DB neurons.

66 citatory postsynaptic potentials (EPSPs) and spontaneous firing in both types of PGN.

67 strate that SDF-1 alpha dramatically reduces spontaneous firing in Cajal-Retzius cells via hyerpolari

68 of NGF to individual MS/DB neurons increased spontaneous firing in cholinergic, but not in the noncho

69 activation to produce hyperexcitability and spontaneous firing in DRG neurons.

70 n was mainly attributable to the increase of spontaneous firing in DTX.

71 of Ih in the excitability and generation of spontaneous firing in hippocampal stratum oriens-alveus

72 To determine whether SFL is caused by spontaneous firing in nociceptive neurons, we studied th

73 Here, we study spontaneous firing in pyramidal neurons (PNs) from rat s

74 of WDR neurons in OA rats but did not alter spontaneous firing in sham rats.

75 potentials during inspiration, but also have spontaneous firing in the absence of synaptic input.

76 esting membrane potential and suppressed the spontaneous firing in the Arc neurons in slice preparati

77 a role of persistent sodium channels in the spontaneous firing in these cardiorespiratory GABAergic

78 The spontaneous firing in these GABAergic neurons was not al

79 Spontaneous firing in TM cells was suppressed by glutama

80 induction of sensitization (i.e., increased spontaneous firing; increased neuronal sensitivity to in

81 rent-clamp recordings demonstrated increased spontaneous firing, lower current threshold, and enhance

82 e found that hCSF increased the frequency of spontaneous firing more than twofold in the two groups o

83 During spontaneous firing, net ionic current flowing between sp

84 Whereas cholinergic activation increases the spontaneous firing (noise) and enlarges the receptive fi

85 serotonergic neuroarchitecture and increased spontaneous firing of 5-HT neurons.

86 Spontaneous firing of a modified Hodgkin-Huxley model ax

87 ndogenous acetylcholine (ACh) release to the spontaneous firing of both regular (probably fusiform ce

88 c neurons in brain slice, including rhythmic spontaneous firing of broad action potentials and, in so

89 tro, with human CSF (hCSF) powerfully boosts spontaneous firing of CA1, CA3 and layer 5 pyramidal neu

90 ill describe the chemokinergic modulation of spontaneous firing of Cajal-Retzius cells, mediated by t

91 Spontaneous firing of cartwheel cells led to activity-de

92 Here we show that changes in spontaneous firing of cartwheel interneurons in the mous

93 The effects of different EEG brain states on spontaneous firing of cortical populations are not well

94 lular amphetamine and methamphetamine on the spontaneous firing of cultured midbrain dopaminergic neu

95 rficial DCN, and support the hypothesis that spontaneous firing of DCN neurons is sustained in part b

96 was shown to induce a transient pause in the spontaneous firing of dopamine neurons.

97 evented the dopamine-induced increase in the spontaneous firing of dopaminergic neurons and the corre

98 ry neurons resulted in hyperexcitability and spontaneous firing of dorsal root ganglia (DRG) neurons,

99 Na(V)1.7 that increase firing frequency and spontaneous firing of dorsal root ganglion (DRG) neurons

100 r beta-hydroxybutyrate, while monitoring the spontaneous firing of GABAergic neurons in mouse substan

101 Local CGP55845 application increased the spontaneous firing of GPe and GPi neurons, suggesting th

102 iquely required for determining the inherent spontaneous firing of hippocampal CA1 pyramids, independ

103 Spontaneous firing of injured nerves is believed to play

104 tion produced a compensatory increase in the spontaneous firing of layer 2/3 pyramidal neurons in acu

105 alamocortical synapse, caused by significant spontaneous firing of LGNd cells (approximately 8 Hz).

106 Electrotonic coupling synchronizes the spontaneous firing of locus ceruleus (LC) neurons in the

107 same slices, naloxone increased the average spontaneous firing of locus coeruleus cells to 0.96 Hz (

108 ide channel in skeletal muscle, which causes spontaneous firing of muscle action potentials (myotonia

109 r goal was to identify currents that trigger spontaneous firing of muscle in the setting of reduced C

110 rimary striatal cultures, caffeine increased spontaneous firing of neurons between 12 and 80 min afte

111 activation, to produce hyperexcitability and spontaneous firing of nociceptive neurons that underlie

112 ion of DRN 5-HT neurons rapidly inhibits the spontaneous firing of olfactory cortical neurons, acting

113 mulation of astrocytes in vivo increases the spontaneous firing of parvalbumin-positive (PV(+)) inhib

114 sibility, we measured the effects of 5-HT on spontaneous firing of projection neurons in the premotor

115 maintaining the frequency and regularity of spontaneous firing of Purkinje cells.

116 We conclude that the spontaneous firing of Purkinje neuron cell bodies depend

117 We tested for modulation of spontaneous firing of Purkinje neurons in cerebellar sli

118 We have examined the spontaneous firing of Purkinje neurons in isolation from

119 y of interneurons, but did suppress aberrant spontaneous firing of pyramidal neurons and was associat

120 Spontaneous firing of SL-S (20.6 +/- 2.2 impulses s(-1))

121 n grip force behavior, and on the evoked and spontaneous firing of spinal wide dynamic range (WDR) an

122 They are believed to be initiated by the spontaneous firing of Starburst Amacrine Cells (SACs), w

123 After DA-depletion, the spontaneous firing of Str-GPe neurons increases, and MC

124 s to quantify the ionic currents driving the spontaneous firing of substantia nigra pars compacta neu

125 rast, WIN55,212,2 hyperpolarized and reduced spontaneous firing of the neighboring hypocretin cells,

126 elatively larger diameter and higher rate of spontaneous firing of the off-centre cells were maintain

127 Excitability and spontaneous firing of the presynaptic VIP+ neurons were

128 onous EPSCs were observed that resulted from spontaneous firing of the same presynaptic fiber.

129 Although superfused 5HT inhibits the spontaneous firing of these cells, the persistence of au

130 Spontaneous firing of ventral tegmental area (VTA) dopam

131 echanical stimulation of the knee and on the spontaneous firing of WDR neurons adds to the growing ap

132 inistration of A-889425 reduced the elevated spontaneous firing of WDR neurons in OA rats but did not

133 Spontaneous firing of WDR neurons was elevated in the OA

134 Spontaneous firings of ectopic foci, coupled with sinus

135 nhibitory postsynaptic currents (sIPSCs) and spontaneous firings of rat ventrolateral periaqueductal

136 s and subsequent recovery and enhancement of spontaneous firings of somatosensory cortical pyramidal

137 e other receptive field led to a decrease of spontaneous firings of the same neuron.

138 When basal intracellular Ca is raised by spontaneous firing or reduced by voltage clamping at sub

139 tanding still to running, without changes in spontaneous firing or stimulus selectivity.

140 ith p.Asn1768Asp channels revealed increased spontaneous firing, paroxysmal-depolarizing-shift-like c

141 Golgi cells were identified by both spontaneous firing pattern and response properties, and

142 Current clamp studies reveal complex spontaneous firing patterns in a subset of neurons, incl

143 The spontaneous firing patterns of striatal cholinergic inte

144 ereby creating mechanisms for control of the spontaneous firing patterns of these neurons.

145 variable interspike intervals, and different spontaneous firing patterns than did type II ventral pal

146 xtrasynaptic GABA(A) receptors may influence spontaneous firing patterns that are critical for the es

147 Spontaneous firing patterns with bursts of action potent

148 ed by glutamatergic antagonists, even though spontaneous firing persists in many "autonomously active

149 AS mice as shown by synaptic plasticity and spontaneous firing properties that resembled those of co

150 During the dark period, the mean spontaneous firing rate (5.00 +/- 0.88 spikes s-1; mean

151 ion than on GSNs and only a 200% increase in spontaneous firing rate (P < 0.05 vs. GSN).

152 The SCN exhibits a daily oscillation in spontaneous firing rate (SFR), but the ionic conductance

153 Synchrony and bursting, as well as spontaneous firing rate (SFR), correlated with behaviora

154 al single action potentials, but the average spontaneous firing rate (spikes/s) was almost 10-fold gr

155 d ocular pressure resulted in differences in spontaneous firing rate and action potential threshold c

156 Furthermore, we show that spontaneous firing rate and burst activity are modulated

157 plasticity depended on the baseline level of spontaneous firing rate and cell excitability.

158 R agonists were all inhibitory, reducing the spontaneous firing rate and hyperpolarizing vGluT2 neuro

159 erse other aspects of central sensitization: spontaneous firing rate and neuronal response magnitude

160 l, a beta-receptor antagonist, decreased the spontaneous firing rate and potentiated the NE-evoked in

161 omol/l) caused a 500% increase (P < 0.01) in spontaneous firing rate and rapid and lasting depolariza

162 bility of cultured neurons by increasing the spontaneous firing rate and reducing the threshold for r

163 wed significant circadian variation in their spontaneous firing rate and resting membrane potential.

164 e arcopallium (RA), show increased intrinsic spontaneous firing rate and soma size when birds are in

165 An increase in whole cell I(Na) changes the spontaneous firing rate and this may be the underlying c

166 dor stimulation, ORNs and PNs display a high spontaneous firing rate but KCs are nearly silent.

167 n 55212-2 (WIN2) and CP 55940 increased SNpr spontaneous firing rate by 13-46%, similar to the effect

168 ow that sustained (>40 min) increases in the spontaneous firing rate can be triggered by activation o

169 ation and skin stimulation did not decrease; spontaneous firing rate did not increase.

170 ed mouse SCN expressed a circadian rhythm in spontaneous firing rate for weeks in culture.

171 The spontaneous firing rate in CA3 neurons transiently decre

172 nduced tinnitus is associated with increased spontaneous firing rate in dorsal cochlear nucleus princ

173 nnel blocker (XE991)-induced increase in the spontaneous firing rate in LHb neurons was smaller.

174 or stromatoxin-1 significantly increased the spontaneous firing rate in NPY neurons from lean mice.

175 ) significantly and reversibly increased the spontaneous firing rate of 37/45 cholinergic interneuron

176 e enzyme, in the patch pipette increased the spontaneous firing rate of all dopamine neurons tested i

177 ns of bicuculline or picrotoxin enhanced the spontaneous firing rate of cortical neurons, indicating

178 Here we report that histamine reduced the spontaneous firing rate of GABAergic preoptic neurons by

179 m of long-term plasticity that regulates the spontaneous firing rate of GoCs in the rat cerebellar co

180 tonic inhibition significantly increases the spontaneous firing rate of granule cells while only mode

181 th agents produced significant reductions in spontaneous firing rate of hippocampal pyramidal neurons

182 However, the spontaneous firing rate of individual retinal ganglion c

183 Ang II (0.3 to 1 mumol/L) increased the spontaneous firing rate of most bulbospinal neurons (+25

184 hydroxybutyrate or acetoacetate) reduced the spontaneous firing rate of neurons in slices from rat or

185 many painful conditions, an increase in the spontaneous firing rate of neurons is often observed in

186 e reveal a tinnitus-specific increase in the spontaneous firing rate of principal neurons (hyperactiv

187 IPSCs evoked at the mean spontaneous firing rate of Purkinje cells (50 Hz) depres

188 onto cerebellar nuclear somata and the high spontaneous firing rate of Purkinje neurons.

189 The rhythmic spontaneous firing rate of RMTg neurons was decreased an

190 Activation of M5 also increased the spontaneous firing rate of SNc neurons, suggesting that

191 of ion channels that is crucial for the high spontaneous firing rate of SNr neurons.

192 athing nigral slices caused increases in the spontaneous firing rate of some dopamine neurons.

193 Spontaneous firing rate of the basket cells is unaltered

194 We show that high salt intake increases the spontaneous firing rate of VP neurons in vivo and that c

195 Hb neurons in brain slices and increased the spontaneous firing rate of VTA dopaminergic neurons in v

196 cadian pacemaker, show a circadian rhythm in spontaneous firing rate that can be recorded in vitro.

197 In dopaminergic neurons the spontaneous firing rate was enhanced by extracellular ap

198 er high spinal transaction demonstrated that spontaneous firing rate was intrinsic to the EMNs and wa

199 afterhyperpolarization, which increases the spontaneous firing rate without affecting the resting me

200 In sensitized rats LC neurons had a higher spontaneous firing rate, and clonidine-an alpha2A-adrene

201 esponse probability correlated strongly with spontaneous firing rate, but weakly with tuning properti

202 the cells underlying these events have a low spontaneous firing rate, unlike the cells giving rise to

203 ptin neurons, which also exhibited increased spontaneous firing rate.

204 n electrophysiological properties other than spontaneous firing rate.

205 size, shape, input resistance, I(h) size, or spontaneous firing rate.

206 nsmitter release, and, consequently, reduced spontaneous firing rate.

207 nd that endogenous 5-HT could roughly double spontaneous firing rate.

208 itory nerve fibers (ANFs) exhibit a range of spontaneous firing rates (SRs) that are inversely correl

209 e sole partner of 10-30 ANFs with a range of spontaneous firing rates (SRs).

210 t stress significantly increased the in vivo spontaneous firing rates and bursting events in suscepti

211 s were identified: silent neurones having no spontaneous firing rates and EPSP-driven neurones having

212 rization triggered long-lasting increases in spontaneous firing rates and firing responses to intrace

213 rats with SCI show significant increases in spontaneous firing rates and in the magnitude and durati

214 Spontaneous firing rates and patterns of cell discharge

215 Densely innervated FTNs had high spontaneous firing rates and pronounced postinhibitory r

216 itory thalamus, however, engagement enhanced spontaneous firing rates but did not affect evoked respo

217 Mean spontaneous firing rates decreased by 58% in the CM/CL n

218 Some neurons increased their spontaneous firing rates during flight, though their inc

219 y prevented the morphine-induced increase in spontaneous firing rates of LC neurons in brain slices.

220 These results show that spontaneous firing rates of midlayer spiny populations a

221 Spontaneous firing rates of TC neurons were higher, and

222 Thresholds and spontaneous firing rates of VCN and MNTB neurons were no

223 and tended to have smaller somata and lower spontaneous firing rates than did type II ventral pallid

224 e time constant, capacitance, and evoked and spontaneous firing rates were all increased in the breed

225 Finally, we found that spontaneous firing rates were shifted up or down by dnCa

226 lative CO activity correlate with changes in spontaneous firing rates within RA and that patterns of

227 s, slower Purkinje-mediated IPSCs, and lower spontaneous firing rates, but rotarod performances were

228 Substantia innominata neurons had lower spontaneous firing rates, more variable interspike inter

229 They have lower spontaneous firing rates, narrower dynamic ranges, and m

230 reliable affinity for palatable tastes, low spontaneous firing rates, phasic responses, and relative

231 trongest modulation to aversive tastes, high spontaneous firing rates, protracted responses, and broa

232 oca neurons while having no direct effect on spontaneous firing rates.

233 orthodromic activation latencies and higher spontaneous firing rates.

234 se two subtypes upregulated or downregulated spontaneous firing, respectively.

235 ous pain behavior is associated with ongoing/spontaneous firing (SF) in adult DRG C-fiber nociceptors

236 ty of the neuronal firing decreases from the spontaneous firing state value when the attractor networ

237 tials in SCN neurons during a period of slow spontaneous firing such as occurs during nighttime.

238 perpolarization current (IAHP) and increased spontaneous firing through SK channel suppression, indic

239 ma, and control the frequency and pattern of spontaneous firing through their close association with

240 ing somatic hyperpolarizations that silenced spontaneous firing to approximately 150 Hz during sponta

241 amus, a cell type where BK currents regulate spontaneous firing under distinct day and night conditio

242 In slice preparations, spontaneous firing was detected in CA1 pyramidal neurons

243 urons and voltage-gated Ca(2+) currents, but spontaneous firing was diminished by riluzole, demonstra

244 Spontaneous firing was driven by the combined action of

245 Spontaneous firing was observed in subsets of neurons in

246 Spontaneous firing was significantly reduced by blockers

247 By simulating synaptic release during spontaneous firing, we found that recruitment of low-Pr

248 ased synchrony and bursting of fusiform cell spontaneous firing, which correlate with frequency-speci

249 suggest that strong somatic stimuli decrease spontaneous firing while increasing depolarization-evoke

250 rea by comparing voltage trajectories during spontaneous firing with ramp-evoked currents in voltage