ライフサイエンスコーパス: sporulate

1 selection for one phenotype: the decision to sporulate.

2 species-specific and within which the cells sporulate.

3 ow a replication initiation mutant (dnaA) to sporulate.

4 sses this checkpoint, allowing zip1 cells to sporulate.

5 onstructed with this mutation were unable to sporulate.

6 or to the first meiotic division and fail to sporulate.

7 fluoride, but homozygous diploids failed to sporulate.

8 ic dyads predominate when some glc7 diploids sporulate.

9 2/HTA2-HTB2) grow vegetatively, but will not sporulate.

10 rebs cycle, had a greatly reduced ability to sporulate.

11 s, and homozygous ssp1 diploid cells fail to sporulate.

12 ed, cells aggregate into fruiting bodies and sporulate.

13 the ability of cells at low cell density to sporulate.

14 henotypic characteristics and the ability to sporulate.

15 in a threshold level of phosphorylated Spo0A sporulate.

16 ls of M. truncatula, P. pachyrhizi failed to sporulate.

17 east, strains expressing human PP1 failed to sporulate.

18 res called fruiting bodies, where they later sporulate.

19 g H2A S122 are defective in their ability to sporulate.

20 ch that antibiotics are produced as a colony sporulates.

21 ve aconitase that was still able to bind RNA sporulated 40x more efficiently than did an aconitase nu

22 gression of multicellular differentiation in sporulating actinomycete bacteria.

23 suggesting the role of BldD is conserved in sporulating actinomycetes.

24 l SALP that is functionally conserved in all sporulating actinomycetes.

25 Hp2 transcription is spatially restricted to sporulating aerial hyphae in wild-type S. coelicolor.

26 ygous for the mre11-H125N mutation failed to sporulate and accumulated unresected double-strand break

27 tripeptide but still retained the ability to sporulate and/or become competent.

28 e deficient in rippling and aggregation, but sporulated and produced C-factor at wild-type levels.

29 However, the rad51-K191R/rad51-K191R diploid sporulated and the haploid spores showed high viability,

30 The diploid was sporulated and the top3 :: kan (R)spores went through fo

31 is genes encoding SASPs can be found in many sporulating and nonsporulating bacteria, but they are no

32 cerevisiae formed sharply divided layers of sporulating and nonsporulating cells.

33 The family contains both sporulating and nonsporulating genera.

34 act cooperatively to block sister cells from sporulating and to cause them to lyse.

35 gK deletion (DeltasigK) mutant was unable to sporulate, and solventogenesis, the characteristic stati

36 ifferences in morphology, the mutant did not sporulate, and the strain lost the ability to synthesize

37 in with a high phosphoglycerate mutase level sporulated, and the spores germinated and went through o

38 ectron cryotomographic images of vegetative, sporulating, and germinating A. longum cells showing tha

39 he roles of Kar3p in meiosis I. vik1 mutants sporulate at wild-type levels, but have reduced spore vi

40 that normally arrest in meiotic prophase to sporulate at wild-type levels, though sporulation is del

41 The ccpA mutant strain sporulated at a 60-fold lower efficiency than the wild-t

42 l mutant formed abnormal fruiting bodies and sporulated at about 10% the level of wild type.

43 ited defective developmental aggregation and sporulated at only 0.02-15% of the wild-type level.

44 tter accumulation of the chimeric protein in sporulating B. subtilis and more efficient processing by

45 ulation of sigmaH-dependent transcription in sporulating B. subtilis cells.

46 luorescent protein (GFP) or hexahistidine in sporulating B. subtilis or in Escherichia coli engineere

47 quired for RIP of pro-sigmaK-GFP chimeras in sporulating B. subtilis.

48 to the asymmetrical location of septation in sporulating Bacilli.

49 polypeptide to the envelope of predivisional sporulating bacilli.

50 geting both polypeptides to the cell wall of sporulating bacilli.

51 Sporulating Bacillus subtilis cells assemble a multimeri

52 Sporulating Bacillus subtilis cells assemble a transenve

53 In sporulating Bacillus subtilis cells, SpoIIIE translocate

54 expression in the mother cell compartment of sporulating Bacillus subtilis involves sequential activa

55 o-sigma(K) in the mother cell compartment of sporulating Bacillus subtilis involves SpoIVFB and is go

56 mother cell-specific transcription factor of sporulating Bacillus subtilis that is derived from an in

57 In the mother cell of sporulating Bacillus subtilis, a regulatory network func

58 mother cell-specific transcription factor of sporulating Bacillus subtilis, is derived from an inacti

59 r produced in the mother cell compartment of sporulating Bacillus subtilis.

60 logical changes exhibited by the Z ring in a sporulating Bacillus subtilis; is used to calculate the

61 Current models of aerial development by sporulating bacteria and fungi postulate a role for surf

62 Sporulating bacteria need to temporally coordinate DNA r

63 known about the mechanism by which these non-sporulating bacteria reactivate.

64 sporulation genes have close homologs in non-sporulating bacteria, including cyanobacteria, proteobac

65 In sporulating bacteria, which undergo asymmetric cell divi

66 yotomography, we show that the Gram-negative sporulating bacterium Acetonema longum synthesizes high-

67 Here we show that the Gram-negative sporulating bacterium Acetonema longum synthesizes propa

68 Inhalational anthrax is caused by the sporulating bacterium Bacillus anthracis.

69 ation in Bacillus subtilis, a gram-positive, sporulating bacterium.

70 nically on nutrient agar, and vegetative and sporulated biomasses were analyzed by Curie-point pyroly

71 lopmental phenotype: both aggregate, neither sporulates, both prolong rippling.

72 were compared in a rabbit ileal loop model, sporulating (but not vegetative) culture lysates of the

73 cells that activate the tagA promoter do not sporulate, but instead form part of the outer basal disc

74 During the recovery phase, cells efficiently sporulated, but this required the proteolysis of Sda.

75 kA+ cells; however, they could be induced to sporulate by addition of antibodies specific to the MYC

76 hen cells of the citB mutant were induced to sporulate by resuspension in a poor medium.

77 CPE is produced by sporulating C. perfringens cells in the small intestinal

78 DPA synthase was purified from extracts of sporulating C. perfringens cells.

79 lation in the mother cell compartment of the sporulating cell and that its transcription is sigma(E)

80 SpoIVFB-GFP localizes to a region of the sporulating cell known as the outer forespore membrane,

81 d which is missing from TasA isolated from a sporulating cell lysate.

82 n Gram-negative bacteria and reveal that the sporulating cell must overcome similar challenges in ass

83 f asymmetric septation near each pole of the sporulating cell.

84 a factor, delta K, in the mother cell of the sporulating cell.

85 cell and spore peripheries in vegetative and sporulating cells and colocalized with actin structures.

86 ion of sigmaH, but the activity of sigmaH in sporulating cells and in cultures at neutral pH is stimu

87 high levels of these enzymes are present in sporulating cells and in dormant spores.

88 lr gene, which encodes Alr, is restricted to sporulating cells and that the bulk of alr transcription

89 form the asymmetric septum characteristic of sporulating cells and were defective in transcription of

90 which are present in the soluble fraction of sporulating cells appear to function independently of en

91 We find that sporulating cells are heterogeneous in their expression

92 s in a switch-like increase in the number of sporulating cells at a threshold of KinA.

93 cZ fusion made it possible to identify early sporulating cells by immunofluorescence microscopy.

94 Sporulating cells contain two sister chromosomes that ar

95 Sporulating cells divide asymmetrically, generating a la

96 growing cells dividing symmetrically and in sporulating cells dividing asymmetrically.

97 oring pASspo was significantly delayed, with sporulating cells exhibiting altered morphology.

98 The sporulating cells feed on the nutrients thereby released

99 f filaments that were generated by depleting sporulating cells for the cell division protein.

100 sence of BofC, the amount of SpoIVB found in sporulating cells is substantially reduced, although Spo

101 We show that motile, matrix-producing, and sporulating cells localize to distinct regions within th

102 acillus subtilis cannibalism system in which sporulating cells lyse nonsporulating siblings.

103 sults suggest that a rising level of GerE in sporulating cells may first activate cotD transcription

104 Sporulating cells of a ybaN ytrI double mutant and of a

105 re found to be expressed at the same time in sporulating cells of B. anthracis and immediately coloca

106 In sporulating cells of B. subtilis FtsZ is recruited to po

107 accumulation in the forespore compartment of sporulating cells of Bacillus subtilis showed that the p

108 Sporulating cells of Bacillus subtilis undergo a highly

109 Sporulating cells of Bacillus subtilis undergo an unusua

110 be active in the mother cell compartment of sporulating cells of Bacillus subtilis, the same compart

111 In sporulating cells of Bacillus subtilis, the serine pepti

112 DivIVA has a second, quite separate role in sporulating cells of Bacillus subtilis.

113 Sporulating cells of the mutant reach the stage of asymm

114 augmented transcription of the cotG gene in sporulating cells of the sodA mutant.

115 In sporulating cells of these strains, we frequently observ

116 pressed only in the forespore compartment of sporulating cells of this organism.

117 One mutant resembles the null mutant, as sporulating cells of this strain lack the cortex and the

118 Overproduction of pro-sigmaK in sporulating cells resulted in more pro-sigmaK in the mem

119 In sporulating cells Spo14 is phosphorylated and relocalize

120 a membrane SNARE subunits, Ssop and Sncp, in sporulating cells suggests that these proteins act in co

121 specifically eliminates, through cell lysis, sporulating cells that assemble the envelope incorrectly

122 number of minicells during growth and caused sporulating cells to complete asymmetric septation more

123 ed us to discover that up to 8% of wild-type sporulating cells trigger premature germination during d

124 Tocheva et al. examined sporulating cells using ECT and fluorescence microscopy

125 complex, the level of SpoIVFA in extracts of sporulating cells was examined by Western blot analysis.

126 ar pattern of localization observed in early-sporulating cells was superimposable with the bipolar pa

127 ells, thin sections of late-log-phase cells, sporulating cells, and free spores were reacted first wi

128 nt transiently in the asymmetrical septum of sporulating cells, and its availability may play a role

129 In the mother cell compartment of sporulating cells, expression of the sigE gene, encoding

130 the protein accumulates at the replisome in sporulating cells, likely through a direct interaction w

131 he mother cell and forespore compartments of sporulating cells, though expression is expected to be r

132 are present in the GpA context in mRNA from sporulating cells, which is consistent with the preferre

133 ted to division sites in both vegetative and sporulating cells.

134 vor the assembly of complexes with Spo20p in sporulating cells.

135 tative cells and at the asymmetric septum in sporulating cells.

136 he SNARE complex, which is necessary only in sporulating cells.

137 o construct three-dimensional projections of sporulating cells.

138 were localized to an internal compartment in sporulating cells.

139 n as the DNA template for extracts made from sporulating cells.

140 ns are also present at substantial levels in sporulating cells.

141 er that initiates peptidoglycan synthesis in sporulating cells.

142 rulation and resulting in lysis of defective sporulating cells.

143 t in phenotypic variation between individual sporulating cells.

144 th medium and had greatly reduced ability to sporulate compared to the wild type due to a block at st

145 nic Bacilli and Clostridia, whose ability to sporulate contributes to their environmental persistence

146 beta2 toxin during vegetative growth and in sporulating culture, providing the first evidence that,

147 Hopene was produced by fully sporulated cultures of S. scabies on solid ISP4 (Interna

148 NA libraries constructed from vegetative and sporulating cultures of C. zeae-maydis.

149 ualize penicillin-binding proteins (PBPs) in sporulating cultures of Streptomyces griseus.

150 and that this message was detectable only in sporulating cultures of the transformants or NCTC 8239.

151 in meiotic gene repression in precommitment sporulating cultures returning to vegetative growth.

152 However, visualization of mitochondria in sporulating cultures reveals morphological defects assoc

153 We find that exposure of sporulating cultures with >40 Gy (4-krad) X-rays stalls

154 ing of both types of markers was examined in sporulating cultures, the vacuolar protease activity was

155 ified in membranes prepared from growing and sporulating cultures.

156 logical inhibition of Hsp90 with macbecin in sporulating diploid cells also blocked spore formation,

157 Furthermore, a larger fraction of the sporulating diploids arrest after the first meiotic divi

158 llus subtilis in that cells lacking 6S-1 RNA sporulate earlier than wild-type cells.

159 redC to redF mutants developed and sporulated early, resulting in small, numerous, and diso

160 In addition, the ssfR null mutant sporulated ectopically in phosphate starvation medium.

161 growth in minimal medium, and was unable to sporulate efficiently in nutrient broth sporulation medi

162 tic in that only a portion of the population sporulates even under optimal conditions.

163 Furthermore, crtf-nulls also fail to sporulate, even under conditions that bypass the depende

164 However, such aerial hyphae fail to sporulate, exemplifying the need to co-ordinate the timi

165 These sporulating filamentous bacteria are remarkably synchron

166 l pathogen Histoplasma capsulatum grows in a sporulating filamentous form in the soil and, after inha

167 e of interest for Streptomyces coelicolor, a sporulating, filamentous bacterium with a large, linear

168 testinal epithelium, grow filamentously, and sporulate from their distal ends.

169 Aspergillus fumigatus is a sporulating fungus found ubiquitously in the environment

170 Aspergillus fumigatus is a sporulating fungus found ubiquitously in the environment

171 the orders Bacillales and Clostridiales can sporulate, generating dormant and resistant spores that

172 Bacillus anthracis is a sporulating Gram-positive bacterium that is the causativ

173 te its complex karyotype, this diploid, when sporulated, had a high frequency of viable spores.

174 generate a mature spore once the decision to sporulate has been made is unaffected by 6S-1 RNA, and,

175 y laurel (Umbellularia californica), the key sporulating host for this pathogen, and negatively corre

176 B. subtilis dacC insertional mutant grew and sporulated identically to wild-type cells, and dacC and

177 Most strains were also able to sporulate in chimerae with each other, but 2 pairs faile

178 Myxococcus xanthus can sporulate in either of two ways: at the end of the progr

179 d or water-spread conidia infect ash and may sporulate in planta, as well as in forest debris.

180 controls the commitment of this organism to sporulate in response to nutrient deprivation and severa

181 ecovered in a mutant screen for strains that sporulate in the absence of signals from prestalk cells.

182 fringens type A isolates when these bacteria sporulate in the gastrointestinal tract.

183 Ingested C. perfringens vegetative cells sporulate in the intestinal tract and produce an enterot

184 ing sporulation and since C. perfringens can sporulate in the intestines.

185 odel species, Streptomyces venezuelae, which sporulates in liquid culture.

186 ticated and undomesticated wild-type strains sporulating in liquid and on solid media.

187 he master control element in the decision to sporulate is the response regulator, Spo0A, which compri

188 The ultimate decision to sporulate is, however, stochastic in that only a portion

189 Moreover, homozygous lig4 mutant diploids sporulate less efficiently than isogenic wild-type cells

190 arly on, whereas the RapA/PhrA subpopulation sporulates less synchronously throughout later stationar

191 genome architecture and may be key to their sporulating lifestyle.

192 on appears normal in the mutant, it fails to sporulate (<10(-6) the wild-type number of viable spores

193 he bacterium, designated strain MLFW-2, is a sporulating member of a deeply branching lineage within

194 pA-phrA operon is heterogeneously induced in sporulating microcolonies.

195 ression observed in in vitro cultures of non-sporulating mycelium.

196 a spo0A knockout strain (SKO1) that neither sporulates nor produces solvents.

197 stinal histopathological damage, but neither sporulating nor vegetative culture lysates of the cpe kn

198 motility, but they fail to aggregate and to sporulate normally.

199 strains lacking SpoVAF or SpoVAEa and SpoVAF sporulated normally, and the spores had normal DPA level

200 itution at the native chromosomal bldM locus sporulated normally.

201 phage vector and gave smaller colonies that sporulated normally.

202 A yhcN mutant sporulates normally and yhcN spores have identical resis

203 They include the ability of bacteria to sporulate, of pathogens to survive antibiotic treatment,

204 e with a slight brownish tint that failed to sporulate on standard media.

205 Infecting BFTE cells with sporulated oocysts provided a reproducible and quantitat

206 ed with GLC7 mutations, such as inability to sporulate or, in cells bearing the glc7Y-170 allele, lac

207 Many mutant cells sporulate outside the fruiting bodies.

208 cient in Mg2+ they overproduce actinorhodin, sporulate poorly and form crenellated colonies.

209 mum3 mutants sporulate poorly and the spores produced are inviable.

210 In addition, mms4 diploids were observed to sporulate poorly.

211 The endocytosis-deficient mutant, end3Delta, sporulated poorly and the spores produced lost resistanc

212 atps1 mutant failed to synthesize trehalose, sporulated poorly and was greatly attenuated in pathogen

213 Multiple fungal isolates sporulated poorly or not at all, displaying unusual colo

214 The sgs1 null mutant sporulates poorly and displays reduced spore viability.

215 orulated powders of CytA in a 1:3 ratio with sporulated powders of a CryIVA, CryIVB, and CryIVD strai

216 tion, was completely suppressed by combining sporulated powders of CytA in a 1:3 ratio with sporulate

217 that cells that have entered the pathway to sporulate produce and export a killing factor and a sign

218 ulent isolate Taiwan 80-2 grows extensively, sporulates profusely, and produces a compatible reaction

219 Uninduced cells sporulate rather synchronously early on, whereas the Rap

220 orulation, Streptomyces griseus is unable to sporulate, retaining the sonication sensitivity of nonsp

221 Mycobacterium genus have been considered non-sporulating, rod-like shaped.

222 IR exposure of sporulating S. pombe cells induced misrepair and irrepar

223 d media, strains in which tylP was disrupted sporulated significantly earlier than wild type and, in

224 Mutant SJ175 sporulates sooner and more abundantly than the wild type

225 When sporulated, spo12 mutants undergo a single meiotic nucle

226 d be produced during both the vegetative and sporulating stages of growth.

227 A cac0437 mutant hyper-sporulated, suggesting that Cac0437 is a modulator that

228 Its genome indicates a motile, sporulating, sulfate-reducing, chemoautotrophic thermoph

229 When slk19 mutants were induced to sporulate they completed events characteristic of meioti

230 d-type level, whereas the pdhD mutant strain sporulated to 55% of the wild-type level.

231 The pdhB and pdhC mutants sporulated to only 5% of the wild-type level, whereas th

232 Because a codY-null mutant was able to sporulate under conditions of nutrient excess, CodY also

233 Cells of B. subtilis enter the pathway to sporulate under conditions of nutrient limitation but de

234 Cells of Bacillus subtilis triggered to sporulate under conditions of rapid growth undergo a mar

235 tilize HK proteins to adapt to stress, grow, sporulate, undergo morphogenesis, mate, sense anti-funga

236 Bacteria of Bacillus species sporulate upon starvation, and the resultant dormant spo

237 l to develop spores in a pure population but sporulate well in chimerae with wild type cells.

238 Mutants lacking AcbA sporulate well only when developed in chimeras with WT c

239 ree, L66A, I90A and H101A, gave strains that sporulated well in the absence of both KinA and KinB.

240 urround the mother cell and the forespore in sporulating wild-type cells and mutant cells that do not

241 in (i.e. pro-sigmaK and sigmaK) was lower in sporulating wild-type cells than in a gerE mutant.

242 In the current study, after confirming that sporulating wild-type SM101 cultures produce SigF (from

243 cells expressing the haploid mating type to sporulate with kinetics that are indistinguishable from

244 le mutant lacking all six genes was found to sporulate with slightly higher efficiency than the wild

245 ned with the pch2 checkpoint mutation, cells sporulate with wild-type efficiency and crossing over oc

246 at a gastrointestinal isolate of B. subtilis sporulates with high efficiency during growth, bypassing

247 -a potential defense against cheaters, which sporulate without contributing to the stalk.

248 me in which the extra chromosome is circular sporulates without a delay, indicating that telomeres ar

249 In addition, the mutant can sporulate, without aggregation into raised mounds, under

250 ty is required for full induction of MCK1 in sporulating yeast cells.

251 iosis II to sequester the dividing nuclei in sporulating yeast.