ライフサイエンスコーパス: spreading

1 key role in driving macrophage lamellipodial spreading.

2 er formation and impaired cell migration and spreading.

3 1 (PSGL-1) inhibited integrin-dependent cell spreading.

4 actions between ParB dimers is necessary for spreading.

5 in-rich mature fibrillar adhesions, and cell spreading.

6 rsistent infection and enhanced host-to-host spreading.

7 t not as a direct barrier to heterochromatin spreading.

8 lysine 20 marks, and is subject to chromatin spreading.

9 used for their intercellular propagation and spreading.

10 tion at promoters and led to heterochromatin spreading.

11 changes in cell size lead to medial-lateral spreading.

12 for SINE elements, predicted to impair XIST spreading.

13 with pathological conditions, such as tumor spreading.

14 integrin activation, cell adhesion, and cell spreading.

15 er multiple kilobases in a phenomenon called spreading.

16 sional lattice, we observe ballistic quantum spreading.

17 hoA leads to stress fiber formation and cell spreading.

18 eclude assessment of the role of LBR in Xist spreading.

19 on rate that markedly suppresses the disease spreading.

20 1 slowed cell migration and accelerated cell spreading.

21 le for this process of seeding and pathology spreading.

22 A damage response and limits heterochromatin spreading.

23 g whereas FlnB inhibited cells show enhanced spreading.

24 beta3-mediated outside-in signaling and cell spreading.

25 ive years ago in the Southeast, and is still spreading.

26 p2/3 impairs lamellipodia formation and cell spreading.

27 sion on networks, such as rumour or epidemic spreading.

28 tism might suggest an early phase of crustal spreading.

29 als may utilize preemptive measures to avoid spreading a disease.

30 ors introduced by noise from multiplying and spreading, a fault-tolerant computational architecture i

31 ion defect is correlated with decreased cell spreading, abnormal focal adhesions, changes in the orga

32 um falciparum malaria, but ACT resistance is spreading across Southeast Asia.

33 polysaccharide substrates by preferentially spreading across the surface perpendicular to the axis o

34 reotypic pattern consistent with progressive spreading along anatomical pathways.

35 in fact involve only few intermediate steps, spreading along the many weak links.

36 rated that wrinkled surfaces can guide water spreading along wrinkle orientation, and hence switchabl

37 p1a(G12V) or Radil cause an increase in cell spreading and adhesion to fibronectin, which are both re

38 ust be tightly controlled to prevent it from spreading and causing irreparable damage.

39 CF-conditioned media distinctly enhanced CM spreading and contractile activity, which was shown by p

40 Addition of EGF at that point increases spreading and contractions, but this can be blocked by m

41 ived factor 1/CXCR4 inhibition impaired cell spreading and delayed the resolution of permeability aft

42 Using DNA fiber spreading and direct visualization of replication interm

43 We show that S1P promotes cell spreading and endothelial barrier function through S1PR1

44 ted histone deacetylation in heterochromatin spreading and gene silencing.

45 used for studying mechanisms of initiation, spreading and inheritance of DNA methylation, and for th

46 cordingly, PTN promoted Mac-1-dependent cell spreading and initiated intracellular signaling manifest

47 ffect the risk of MP pollution prior to land spreading and may have implications for legislation gove

48 scous behavior on the same timescale as cell spreading and migration and thus enables efficient cell

49 and robustness, but critically inhibits cell spreading and migration, hampering tissue regeneration.

50 jury, restoring epithelial integrity through spreading and migration.

51 d proliferation, as well as endothelial cell spreading and monolayer formation.

52 (EGFR) interacts with integrins during cell spreading and motility, but little is known about the ro

53 We observe the spreading and partial refocusing of the excitation in th

54 nd elastic modulus) that enhanced viability, spreading and proliferation of encapsulated odontoblast-

55 and stiffness enhanced OD21 cell viability, spreading and proliferation, as well as endothelial cell

56 The spreading and regulation of epigenetic marks on chromoso

57 unveil the molecular mechanism by which cell spreading and RhoA GTPase activity control FA formation

58 e conditions, EGFR or HER2 activity increase spreading and rigidity-sensing contractions on rigid, bu

59 re desirable due to the ease of application, spreading and that they cause little to no discomfort to

60 resulting from impeded actin dynamics, cell spreading, and cell cycle arrest.

61 alpha- and delta-granule secretion, platelet spreading, and clot retraction were not markedly affecte

62 yoblasts, as well as triggered lamellipodia, spreading, and fusion of myoblasts through the signaling

63 bition negated ICAM-1 mediated lamellipodia, spreading, and fusion of myoblasts.

64 nt for strategies of immunization in disease spreading, and influence maximization in opinion dynamic

65 oted integrin alphaMbeta2-mediated adhesion, spreading, and migration of cells on iC3b and fibrinogen

66 on events, including adhesion strengthening, spreading, and migration under flow conditions.

67 Delta20-induced inhibition of adhesion, cell spreading, and neurite outgrowth, as well as for RhoA ac

68 s in determining the degree of their spatial spreading, and thereby the degree of the spine specifici

69 ve plasmid transfer is an important means of spreading antibiotic resistance .

70 nisms underlying ATII cell proliferation and spreading are not well understood.

71 be the major vector source for the species' spreading around the globe.

72 axis geometry reinforces axial bias in skin spreading around the mouse embryo body.

73 etrospective study identified PLA2R1 epitope spreading as a potential indicator of poor prognosis.

74 In silico modeling, mouse fibroblasts spreading assays, and in vivo overexpression assays usin

75 n (58.8%) of the 17 patients who had epitope spreading at baseline and were treated with rituximab sh

76 We propose that epitope spreading at baseline be considered in the decision for

77 In adjusted analysis, epitope spreading at baseline was associated with a decreased re

78 ed with rituximab showed reversal of epitope spreading at month 6.

79 This model can inform decisions about spreading basin operation policies and the development o

80 illustrate how delivering recycled water to spreading basins could be optimally implemented.

81 ater to augment groundwater recharge through spreading basins represent cost-effective opportunities

82 r recycled water to underutilized stormwater spreading basins.

83 he oil-surfactant concentration controls the spreading behavior of oil on water, as well as the peak

84 ext of their cellular environments and their spreading between cells and organs.

85 ted to promote cell migration, adhesion, and spreading, but its mechanisms of action remain uncertain

86 ypothesised that PGI2 could reverse platelet spreading by actin cytoskeletal modulation, leading to r

87 tf gene family can increase their chances of spreading by using poisons to kill other alleles, and an

88 nitiation of twitching was associated with a spreading calcium wave in a dorsal muscle bundle.

89 Rumor spreading can have a significant impact on people's live

90 lta-deficient mice, but also aberrant T-cell spreading, cell-cell interaction, and migration.

91 of hot mantle rock upwelling beneath oceanic spreading centers causes it to exceed the melting point

92 recipitation occurs at mid-ocean ridge (MOR) spreading centers, both in the form of plume particles a

93 We find that spreading condensation from a specific binding site can

94 acellular environment and suggested that its spreading contributes to toxicity, but the mechanism of

95 terized two distinct Cdc8 cables loading and spreading cooperatively on individual actin filaments.

96 teractions frequently led to the most severe spreading defects when mutated, and that a network of bo

97 Spreading depolarization (SD) is a slow propagating wave

98 role of glutamate uptake in the dynamics of spreading depolarization (SD)-the electrophysiological e

99 e of excitatory neurotransmitters to sustain spreading depolarization and activate neuroinflammation.

100 Spreading depolarization clusters were associated with f

101 old for spreading depolarization, and reduce spreading depolarization frequency and amplitude.

102 sion of the P2X7-PANX1 pore complex inhibits spreading depolarization in mice carrying the human fami

103 Spreading depolarization is a wave of neuronal and glial

104 ors also suppress downstream consequences of spreading depolarization such as upregulation of interle

105 X1 pore complex is a critical determinant of spreading depolarization susceptibility and its downstre

106 X1 pore complex is a critical determinant of spreading depolarization susceptibility with important c

107 ibitors elevate the electrical threshold for spreading depolarization, and reduce spreading depolariz

108 Within minutes after spreading depolarization, the neuronal hemichannel panne

109 nction or ablation of the P2x7 gene inhibits spreading depolarization.

110 ase and cyclooxygenase-2 in the cortex after spreading depolarization.

111 were both significantly more likely to have spreading depolarizations (6/7 and 10/12, respectively)

112 l/min over cortical sulci caused clusters of spreading depolarizations (count range: 12-34) in 7/17 a

113 s in sulci/fissures are sufficient to induce spreading depolarizations and acute infarction in adjace

114 chanisms are unknown, although mass cortical spreading depolarizations are hypothesized as a requisit

115 Results further validate spreading depolarizations as a clinical marker of early

116 f 1 ml of clotted blood into a sulcus caused spreading depolarizations in 5/6 animals (count range: 4

117 The association of spreading depolarizations with early brain injury was th

118 Cortical spreading depression (CSD) is likely the underlying phen

119 mice, we show that a single wave of cortical spreading depression (CSD), an animal model of migraine

120 us and evoked activity in naive and cortical spreading depression (CSD)-sensitized trigeminovascular

121 range trigeminovascular neurons by cortical spreading depression (CSD).

122 receded by an aura likely caused by cortical spreading depression (SD).

123 ection analysis) and in vivo (i.e., during a spreading depression event in an anesthetized rat).

124 ntral) trigeminovascular neurons by cortical spreading depression, but not their activation from the

125 This paper shows that cortical spreading depression, the neural correlate of migraine a

126 d the effect of fremanezumab on the cortical spreading depression-evoked activation of mechanosensiti

127 f neurons that showed activation by cortical spreading depression.

128 ts and animals, agriculture, infrastructure, spreading diseases.

129 r lung injury and promotes proliferation and spreading during repair.

130 r (LBR) is necessary and sufficient for Xist spreading during X-chromosome inactivation.

131 aneously disperse within the oil, due to the spreading dynamics of oil on water.

132 om an interplay between network topology and spreading dynamics.

133 ow that the most recent eruption at the fast-spreading East Pacific Rise just North of the Equator in

134 te of these elements would be different when spreading either digestates or raw waste on cropland.

135 n fibers to the cell periphery, and promoted spreading/enlargement of transfected cells.

136 ndamentally change the predicted impact of a spreading epidemic.

137 Salmonella infectious diseases spreading every day through food have become a life-thre

138 Instead, we find that, for a given spreading factor, the small fraction of heat transferred

139 rk, and adhesions coordinate the dynamics of spreading fibroblasts.

140 Systemic sclerosis (SSc) is a spreading fibrotic disease affecting the skin and intern

141 as attained the status of a global pandemic, spreading from affluent industrialized nations to the em

142 rth America during the last interglaciation, spreading from Alaska through continental North America;

143 reasingly coarse temporal features of speech spreading from posterior superior temporal cortex toward

144 ggregated protein rather than to longer-term spreading from seed regions.

145 esting that ROS1 may prevent DNA methylation spreading from TEs to nearby genes.

146 nfection, it invades epithelial cells before spreading from the intestine to the cells of the liver a

147 es when serum is present while migration and spreading generally increase as well.

148 ld deliver more recycled water to the Hansen Spreading Grounds, this system incurs approximately twic

149 -regulated, the mechanism is associated with spreading H3K27me3 modifications at the BdODDSOC2 chroma

150 Epidemic spreading has been studied for a long time and most of t

151 Research into rumor spreading has primarily been based on either model of so

152 In the scratch wound assay of cell spreading, HIF stabilization accelerated, whereas HIF1al

153 ficantly less likely to have the superficial spreading histologic subtype (P = 0.01), occurred in old

154 kely to have BRAF mutations or a superficial spreading histologic subtype (P = 0.05) compared with vo

155 of the disease that initially motivated the spreading hypothesis by Braak and colleagues.

156 A2R1 antibody (PLA2R1-Ab) titers and epitope spreading in a prospective cohort of 58 patients positiv

157 yo to study the principles underlying tissue spreading in a simple cellular environment, devoid of pa

158 Zika virus outbreak is spreading in America.

159 Information spreading in complex networks is often modeled as diffus

160 rocesses mediating tau prion replication and spreading in different brain regions.

161 es often cocirculate and Zika virus has been spreading in geographical regions where DENV is endemic

162 role of MT nucleation from the NE on nuclear spreading in myotubes.

163 Nogo-A, inhibits neurite outgrowth and cell spreading in neurons and Nogo-A-responsive cell lines vi

164 zation events, such as the onset of seafloor spreading in the Labrador Sea.

165 rface, thereby dynamically blocking membrane spreading in the whole-GMPV mode.

166 reat of antimalarial resistance emerging and spreading in treated populations.

167 ring with PD-1 signaling potentiates epitope spreading in tumor-specific responses, a finding with cl

168 lantation in vivo, mouse embryo adhesion and spreading in vitro, as well as N-fucosylation level of t

169 stochemistry and determine its role in viral spreading in vitro.

170 gation and was a prerequisite for prion-like spreading in vivo Remarkably, membranes could catalyze a

171 Also, US28 facilitates HCMV spreading in VSMCs in vitro.

172 tic proliferation of HIV as well as in acute spreading infection of HIV in primary CD4 T cells.

173 and Culex mosquitoes are the main culprits, spreading infection when they bite.

174 osed herein points to optimal strategies for spreading information in social networks and provides a

175 ds deposit precursors and prevents them from spreading into daughter cells during division by subject

176 DP-43 restricted to the amygdala; and TDP-43 spreading into the hippocampus.

177 of scaffold interaction increases, follicle spreading is limited and survival increases.

178 s indeed dramatically reduce cell-free virus spreading, it has little to no effect on direct cell-to-

179 indlin-2 has a dual role during initial cell spreading: it binds paxillin via the pleckstrin homology

180 The role of the medical congress in spreading knowledge in the face of this changing environ

181 nterplay between network growth and epidemic spreading leads to exponential networks for any finite r

182 ssile or flat colorectal polyps or laterally spreading lesions (>/=20 mm) at academic hospitals in Au

183 large colorectal sessile polyps or laterally spreading lesions, it is important to identify those at

184 ssile or flat colorectal polyps or laterally spreading lesions, we associated rectosigmoid location,

185 ontribute to accelerate tumor progression by spreading malignant properties that affect both the tumo

186 Understanding the spreading mechanisms of social contagions in complex net

187 alization radii, estimated through spherical spreading models, fluctuated dramatically during the thr

188 s, but during recent decades, they have been spreading more widely and affecting larger populations.

189 ZIKV is a rapidly spreading mosquito-borne pathogen that has been linked t

190 IKV infection.IMPORTANCE CHIKV is a globally spreading, mosquito-transmitted virus that causes debili

191 erical simulations of models for information spreading, neural dynamics, and behavior adoption and we

192 B cell response, contextualizing the epitope spreading observed in autoimmune disease.

193 ulent diffusivity inferred from the vertical spreading of a tracer to be an order of magnitude larger

194 s to identify those that modulate prion-like spreading of alpha-syn in order to target novel strategi

195 wePSEN1dE9 mice failed to induce seeding and spreading of amyloid-beta pathology in ASC-deficient APP

196 asome activation is connected to seeding and spreading of amyloid-beta pathology in patients with Alz

197 pocampal injection of ASC specks resulted in spreading of amyloid-beta pathology in transgenic double

198 actor (HIF)1alpha promotes proliferation and spreading of ATII cells during repair after lung injury.

199 are interpreted as resulting from localized spreading of boron-rich fertilizers, thus indicating a s

200 Finally, defective spreading of C. muridarum mutants was due to their inabi

201 zymatically cross-linked, which promotes the spreading of cells and the stiffening of nuclei as both

202 o not affect integrin alphaIIbbeta3-mediated spreading of CHO cells on fibrinogen.

203 t reoxidation of small Co NPs is followed by spreading of Co oxide that leads to the formation of Cox

204 o the embryo, directs cell migration and the spreading of embryonic tissue during early development.

205 Rather, they only facilitate the growth and spreading of existing transitional-turbulent spots.

206 via shRNA dramatically altered adhesion and spreading of freshly isolated CD8(+)/CD103(+) lung tumor

207 In this "pushed wave" regime, the spatial spreading of gene drives will be initiated only when the

208 Moreover, our results demonstrate that spreading of H3K4me3 from promoter to gene body regions,

209 phosphorylatable H3.3S10A results in ectopic spreading of H3K9me2 into adjacent euchromatic regions,

210 Strikingly, spreading of H3S10ph at RT transition regions (TTRs) is

211 nit of the 26S proteasome also regulates the spreading of inactive chromatin referred to as heterochr

212 1 -HopAI transformants were defective in the spreading of invasive hyphae and elicited strong defense

213 nvironmental contamination by and subsequent spreading of MDRPa, including a newly designed shower dr

214 The spreading of mesenchymal-like cell layers is critical fo

215 G sites methylated in both cytosines promote spreading of methylation in the CpHpG context in genes p

216 The notion that prion-like spreading of misfolded alpha-synuclein (alpha-SYN) cause

217 Cell-to-cell spreading of misfolded alpha-synuclein (alpha-syn) is su

218 In particular, spreading of neuronal dysfunction within the EC-Hippocam

219 Land spreading of OMW with RP altered the relative proportion

220 The spreading of pathology within and between brain areas is

221 Acquired molecular changes can promote the spreading of primary tumor cells to distant tissues.

222 unneling nanotubes play in the formation and spreading of prion-like assemblies.

223 ocess that may be mediated by the productive spreading of prion-like protein aggregates from a "donor

224 The intercellular spreading of protein assemblies is a major factor in the

225 h may play a general role in restricting the spreading of repressive chromatin in interphase mammalia

226 omosomal synapsis and prevents the efficient spreading of silencing factors into the XY chromatin.

227 important, 6C5 also blocked neuron-to-neuron spreading of tau in a unique three-chamber microfluidic

228 eting extracellular tau species may slow the spreading of tau pathology and possibly cognitive declin

229 nt and implementation of strategies to limit spreading of TB.

230 d in preclinical models in vivo and prevents spreading of the disease to distant sites.

231 lar alterations leading to the onset and the spreading of these diseases are still unknown.

232 A top priority to minimize further spreading of this disease and its potential impact on en

233 e of curvature on the collective crowding or spreading of tissue-synthesizing cells induced by change

234 an model, it is shown that the fast vertical spreading of tracer occurs when it comes in contact with

235 therapeutic concept for reducing metastatic spreading of tumor cells.

236 The viral spreading of US28-deficient HCMV, via culture medium or

237 S1P deficiency impaired aggregation and spreading of washed platelets and profoundly reduced the

238 e acute platelet functions, causing enhanced spreading on Fg and fibronectin and faster clot retracti

239 gnaling dependent functions such as platelet spreading on fibrinogen and thrombin-mediated fibrin clo

240 g GAP-deficient Rasa3 (H794L) show increased spreading on fibrinogen, which in contrast to wild-type

241 er flow, and accelerated clot retraction and spreading on fibrinogen.

242 activity and integrin alphaIIbbeta3-mediated spreading on fibrinogen.

243 e report molecular kinetic analyses of water spreading on hydrophobic surfaces via molecular dynamics

244 mediated through immobilization and cellular spreading on the transwell membrane.

245 These cells complete the processes of spreading onto surfaces, and phagocytosis within 100 s o

246 ayers, CF-conditioned media did not alter CM spreading or MEK-ERK activation.

247 This spreading, or exfoliation, of graphite at an oil/water i

248 Infectious crop diseases spreading over large agricultural areas pose a threat to

249 determined by characterizing hydrophobicity, spreading patterns, and flow behavior on various sized f

250 nical picture resembled meningococcemia with spreading petechiae on legs and arms raising concern for

251 major trade routes played a dominant role in spreading plague in pre-industrial Europe.

252 tachys edulis) represents one of the fastest-spreading plants in the world, due in part to its well-d

253 We assessed the disease spreading potential of the direct and indirect network s

254 Chronic wasting disease (CWD) is a rapidly spreading prion disorder affecting captive and free-rang

255 ive use of limited resources for controlling spreading processes on networks is of prime significance

256 elucidate the effects of social dynamics on spreading processes.

257 in networks' evolution and influence ongoing spreading processes: the strategies individuals adopt wh

258 This ceased as seafloor spreading propagated northwards, opening an equatorial g

259 h dieback fungus Hymenoscyphus fraxineus, is spreading rapidly across Europe.

260 Zika virus (ZIKV) is spreading rapidly into regions around the world where ot

261 orks will provide more accurate estimates of spreading rates.

262 dicts diffusion through social networks when spreading relies on contact with seed nodes while centra

263 However, the cellular mechanisms behind the spreading remain elusive.

264 computational studies have argued that ParB spreading requires cooperative interactions between ParB

265 Cell spreading requires the coupling of actin-driven membrane

266 At ocean spreading ridges, circulation of seawater through rock a

267 e invasion front can produce fluctuations in spreading speed.

268 l invasions, which often exhibit nonconstant spreading speeds, even in simple, controlled settings.

269 , proteinuria, or serum albumin, but epitope spreading strongly correlated with PLA2R1-Ab titer (P<0.

270 ns, with branching included as a directional spreading term.

271 al. describe a mechanism for antiviral RNAi spreading that parallels mammalian adaptive immunity thr

272 is incompletely lifted in the valence band, spreading the hole population among several states at ro

273 leic acid quantification technique, works by spreading the target material across a large number of p

274 ral network in relation to potential disease spreading (the Prostitution network), the strategy of se

275 driving essential platelet processes such as spreading, thrombus consolidation, and clot retraction.

276 Using a laboratory model system (beetles spreading through artificial landscapes), we quantified

277 light-induced contractile signal apparently spreading through gap junctions into neighboring muscle

278 Chinook salmon native to North America are spreading through South America's Patagonia and have bec

279 athogenic coronaviruses, even as MERS-CoV is spreading throughout the Middle East.

280 ositive, highly proliferative, and diffusely spreading, thus recapitulating hallmark molecular and hi

281 r many dynamical processes, from information spreading to accessibility, by disrupting network paths.

282 s SASP through prevention of heterochromatin spreading to allow for exclusion of SASP gene loci from

283 d assembly of monomeric Tau, followed by its spreading to distant brain regions.

284 infections are increasing in number and are spreading to new regions at an unprecedented rate.

285 nt tau protein was restricted in MEC without spreading to other brain regions at one month after tran

286 utbreaks in certain regions (e.g., ST36), or spreading to other regions where they are nonendemic (e.

287 hal effects of HSV infection, with the virus spreading to the brain causing encephalitis.

288 initiated first in the endosperm, only later spreading to the embryo.

289 his response occurs in cortical cells before spreading to the epidermis in L. japonicus While mutant

290 nfirmed the correlation between C. muridarum spreading to the gastrointestinal tract and its pathogen

291 genes tc0237 and/or tc0668 was defective in spreading to the mouse gastrointestinal tract, which cor

292 d, through the equatorial rainforest, before spreading toward eastern and southern Africa.

293 omestic waste, wich is sometimes then burned spreading toxic contaminants.

294 d excitotoxic insult, we replicate secondary spreading toxicity and demonstrate that this process is

295 K-depleted fibroblasts impedes enhanced cell spreading, traction stress, and fibronectin fiber format

296 (BsSpo0J) and characterized their effect on spreading using both in vivo and in vitro assays.

297 Shigella mediates intracellular motility and spreading via actin comet tail formation.

298 ly increased probability of establishing and spreading when entering novel ecosystems.

299 mulation in null FlnA cells impairs enhanced spreading whereas FlnB inhibited cells show enhanced spr

300 tion in adherent platelets, reduced platelet spreading, whilst simultaneously promoting actin nodule