ライフサイエンスコーパス: sprout

1 x cells, which are quiescent and support the sprout.

2 ely to form stable connections with incoming sprouts.

3 and antioxidant capacity of stored mung bean sprouts.

4 the antioxidant capacity of young buckwheat sprouts.

5 o increase the nutritional value of broccoli sprouts.

6 movements of endothelial cells (ECs) within sprouts.

7 ls that form multicellular structures called sprouts.

8 on the phytochemical composition of broccoli sprouts.

9 tions increased the antioxidant potential of sprouts.

10 a useful tool for designing some features of sprouts.

11 hat is critical for navigation of new vessel sprouts.

12 improving the antioxidant capacity of lentil sprouts.

13 d glycitein were not detected in the soybean sprouts.

14 ments may improve consumer quality of stored sprouts.

15 sition and antioxidant activity of rice bean sprouts.

16 ytoskeletal machinery necessary for neuronal sprouting.

17 sm underlying laminar flow-induced lymphatic sprouting.

18 gulate NOTCH1 activity and enhance lymphatic sprouting.

19 lock repolarization and reduce migration and sprouting.

20 were dispensable for IL-31-induced neuronal sprouting.

21 , whereas siRNA-mediated knockdown increased sprouting.

22 oteins that promote ex vivo choroidal vessel sprouting.

23 in the induction of angiogenic genes during sprouting.

24 sis regulates EC rearrangement during vessel sprouting.

25 w growth with little contribution from local sprouting.

26 -8-mediated lymphatic endothelial cell (LEC) sprouting.

27 lutamine and asparagine metabolism in vessel sprouting.

28 ecessary for EC proliferation and angiogenic sprouting.

29 ils both galectin-8- and VEGF-C-mediated LEC sprouting.

30 i1 and Klf2 also markedly impaired lymphatic sprouting.

31 trunk endothelial cells can limit their over-sprouting.

32 th factor-beta, indicating less atrial nerve sprouting.

33 jected into the PNG, indicative of augmented sprouting.

34 sm may even override signals inducing vessel sprouting.

35 uced shear stress to activation of lymphatic sprouting.

36 e deficient in migration, cord formation and sprouting.

37 nctional excitatory synapses, despite robust sprouting.

38 , and aortic ring endothelial cell outgrowth/sprouting.

39 ciated with abnormal hippocampal mossy fiber sprouting.

40 l cell proliferation and ex vivo aortic ring sprouting.

41 tro endothelial tube formation, and spheroid sprouting.

42 unctional blockade of p75(NTR) decreased rMF sprouting.

43 s are maintained, likely due to preferential sprouting.

44 rothermal processing to remove the husk) and sprouts (7-day-old seedlings) affected Fe speciation (Fe

45 ocampus and co-localization with mossy fibre sprouting, a feature of temporal lobe epilepsy.

46 vely the total glucosinolates content in the sprouts, achieving the most significant increases from 3

47 neurons and pyramidal cells in CA1 appear to sprout across the hippocampal fissure to preferentially

48 motor skills, the corticospinal tract (CST), sprout after brain or spinal cord injury.

49 poradic MCI/AD, display impaired cholinergic sprouting after EC lesion.

50 i and from 45% to 118% of increase in radish sprouts after MeJA priming and treatments.

51 e basal parts of the skull and spinal canal, sprouting along the blood vessels and cranial and spinal

52 mary ECs with excess centrosomes in vascular sprouts also had elevated Ser33 p53 phosphorylation and

53 Thus, sprout anastomosis parameters are regulated by VEGFA sig

54 eta1 scaffolds promoted endothelial cells to sprout and branch, forming organized extensive networks

55 hbouring Erbb2-activated cardiomyocytes that sprout and form nascent trabeculae.

56 Alfalfa sprout and lagoon water samples served as model food and

57 r g of E. coli and E. faecium, respectively) sprout and water samples tested positive within 4 and 12

58 us, which raises questions about the role of sprouting and adult neurogenesis in sustaining seizure-l

59 rfering RNAs or GapmeRs inhibited angiogenic sprouting and alignment of endothelial cells in response

60 The effect of soaking, sprouting and cooking on the stability and bioavailabili

61 tion, the potential role of both cholinergic sprouting and dentate hyperactivity in AD symptomatogene

62 autonomous ERK activation rescued lymphatic sprouting and differentiation in flt4 mutants.

63 , and ERK inhibition blocked trunk lymphatic sprouting and differentiation.

64 aam1 cooperatively regulate initiation of EC sprouting and directional migration via MT reorganizatio

65 studies, we found that GDF10 produced axonal sprouting and enhanced functional recovery after stroke;

66 o study chemokine gradient-driven angiogenic sprouting and find that matrix degradability modulates t

67 Endothelial alpha-pv is essential for vessel sprouting and for vessel stability.

68 mber A (CLEC14A) display enhanced angiogenic sprouting and hemorrhage as well as enlarged jugular lym

69 sed its stability, and elevated blood vessel sprouting and in vivo angiogenesis.

70 , the compensatory nature of the cholinergic sprouting and its putative mechanisms remain elusive.

71 A mechanism based on axonal sprouting and occupancy of the vacant synaptic space due

72 sion of GAP43 (P < 0.01), a marker of axonal sprouting and plasticity, in the peri-infarct cortex.

73 ) post-SE infusion of bumetanide reduced rMF sprouting and recurrent seizures in the chronic epilepti

74 r stroke; knocking down GDF10 blocked axonal sprouting and reduced recovery.

75 inating NGF signaling to regulate collateral sprouting and structural plasticity of intact adult axon

76 work reveals that FOS stimulates endothelial sprouting and that perturbation of normal FOS degradatio

77 Erbb2 signalling and prevents cardiomyocyte sprouting and trabeculation.

78 required for VEGFA-induced HRMVEC migration, sprouting and tube formation in vitro and hypoxia-induce

79 ssion in the modulation of HRMVEC migration, sprouting and tube formation.

80 ascular endothelial cell (HRMVEC) migration, sprouting and tube formation.

81 ic flux, and endothelial cell proliferation, sprouting and tubule formation.

82 are found at high concentrations in soybean sprouts and could easily provide the recommended anticar

83 fail to develop front-rear polarized vessel sprouts and exhibit severe angiogenesis defects in the p

84 ve been identified with shape changes in the sprouts and the associated rearrangements of collagen fi

85 omechanical interaction between the invading sprouts and the extracellular matrix.

86 digestibility was determined for the control sprouts and those obtained after tyrosine feeding.

87 or cells-they undergo senescence in vascular sprouts and vessels, which suggests that pathologic outc

88 ance of epithelial placodes that invaginate, sprout, and branch to form small arborized trees by birt

89 effects of hapto- and mechanotaxis on vessel sprouting, and mechano-sensitive dynamic vascular remode

90 migration, tracheal branching, blood vessel sprouting, and the migration of the lateral line primord

91 ociated with adult sensory axonal collateral sprouting, and this association may offer new insights f

92 VEGFR3 also regulates sprouting angiogenesis and blood vessel growth, but to w

93 ls, and to identify novel genes that control sprouting angiogenesis and lineage specification of bloo

94 in tumor endothelial cells, and it promotes sprouting angiogenesis and modulates endothelial functio

95 how that the ectodomain of CLEC14A regulates sprouting angiogenesis and suggests a role for RHBDL2 in

96 anscription factors as crucial regulators of sprouting angiogenesis directly downstream from VEGFA.

97 Sprouting angiogenesis drives blood vessel growth in hea

98 and many other key genes up-regulated during sprouting angiogenesis in both physiological and tumor v

99 Here we show that CLEC14A is a regulator of sprouting angiogenesis in vitro and in vivo.

100 Sprouting angiogenesis is a key process driving blood ve

101 Sprouting angiogenesis is regulated by shedding of the C

102 Blood vessel expansion is driven by sprouting angiogenesis of endothelial cells, and is esse

103 encodes a transcription factor implicated in sprouting angiogenesis) is required for its VEGF-mediate

104 es decreased Dll4/Notch signaling, excessive sprouting angiogenesis, and defects in developmental vas

105 find that ECs dynamically repolarize during sprouting angiogenesis, and excess centrosomes block rep

106 During sprouting angiogenesis, the specification of endothelial

107 While this occurs predominately through sprouting angiogenesis, tumor cells have also been shown

108 on of p56/Lck in murine aortic rings blocked sprouting angiogenesis.

109 overrepresented around genes associated with sprouting angiogenesis.

110 endothelial cell front-rear polarity during sprouting angiogenesis.

111 ic cancer cells (CCs) stimulate blood vessel sprouting (angiogenesis), aimed at restoring O2 delivery

112 a molecular hierarchy that induces vascular sprouting, APC vessel niche affinity and APC vessel occu

113 disease, associated with distal motor axonal sprouting as part of the reinnervation response that dev

114 t of the MDM2/p53-IGF1R axis enhances axonal sprouting as well as functional recovery after spinal co

115 CC2, and ectopic recurrent mossy fiber (rMF) sprouting as well as telemetric electroencephalographic

116 Nerve fiber density and sprouting, as well as expression of NGF and NTRK1, are s

117 tly suppressed angiogenesis in the choroidal sprouting assay ex vivo and inhibited ocular development

118 ght angiogenic activities in a microvascular sprouting assay using choroid explants.

119 man umbilical vein endothelial cell spheroid-sprouting assay, we found CLEC14A to be a regulator of s

120 rings from VimKO mice and in endothelial 3D sprouting assays can be rescued by reactivating Notch si

121 ovement in mouse embryonic stem cell-derived sprouting assays.

122 opic granule cells, mossy cells, mossy fiber sprouting, astrogliosis, and GABAergic interneurons.

123 These results suggest that newly sprouted axon collaterals do not preferentially innervat

124 d, raising the question of whether the newly sprouted axons are able to form functional synapses.

125 nd optimize functional reconnection by newly sprouted axons in the injured CNS.

126 carpan phytoalexins forms were identified in sprouts, being malonylated formononetin glycoside, formo

127 e an initial signal orchestrating pulp nerve sprouting beneath carious injury, a critical step in den

128 ls (GTPs) and sulforaphane (SFN) in broccoli sprouts (BSp) on neutralizing epigenetic aberrations in

129 were increased in neurons during collateral sprouting but decreased following injury, suggesting tha

130 mous inhibition of ERK prevented endothelial sprouting, but did not prevent initial artery differenti

131 s also contributed to functional mossy fiber sprouting, but exhibited less synaptic depression.

132 mechanistic insight in the control of vessel sprouting by glycolysis, and suggesting anti-glycolytic

133 ectopic expression of miR-200 inhibited this sprouting by indirectly reducing the protein levels of P

134 or the glycolytic activator PFKFB3 in vessel sprouting by regulating cytoskeleton remodelling, migrat

135 Red clover sprouts can be considered as a source of phytoestrogens

136 display reduced Notch activity and increased sprouting capacity.

137 Here we show that newly sprouted CF collaterals innervate multiple Purkinje cell

138 vbeta3 integrin binding promoted endothelial sprout clumping in vitro and leaky vessels in vivo.

139 After transgene suppression, resistant MNs sprout collaterals to reinnervate previously denervated

140 el of phytonutrients in mungbean and soybean sprouts compared to mature mungbean grain and vegetable

141 al composition changes promoted by different sprouting conditions of four varieties of Brassica olera

142 noninjured neurons, often termed collateral sprouting, contributes to both adaptive and pathological

143 Results suggest that Se-enriched chickpea sprouts could represent a good source of dietary Se and

144 of isoflavones, especially formononetin were sprouts cultivated for 10 days under continuous white li

145 as well as the antioxidant capacity of bean sprouts (cv Dalia).

146 r length as well as the morphology of axonal sprouting, deep within the tissue.

147 nhibiting glutaminase 1 (GLS1) caused vessel sprouting defects due to impaired proliferation and migr

148 Impaired sprouting during the MCI stage may contribute to the fas

149 R2 signalling pathway as well as ablation of sprouting ECs diminished tumour vascularization and grow

150 for dynamic repolarization and migration of sprouting ECs that contribute to blood vessel formation.

151 Generally, except for 3-day-old sprouts, elicitation increased phenolic content (in resp

152 We also find that sprout elongation and branching associates with a highly

153 nally, we show that cleaved CLEC14A binds to sprouting endothelial tip cells.

154 During vessel sprouting, endothelial cells (ECs) dynamically rearrange

155 application of elicitors in bean seed during sprouting enhances their nutraceutical properties.

156 gen and aspartate to asparagine) impaired EC sprouting even in the presence of glutamine and asparagi

157 These results suggest that the peanut sprout exerts high anti-inflammatory effects that may be

158 d the data collected in-situ from angiogenic sprouting experiments and identified the differentiated

159 terations of endothelial-tip-cell selection, sprout extension and anastomosis are the basis for vascu

160 ll selection determines the length of linear sprout extension at the expense of branching, dictating

161 ut must develop front-rear polarity to allow sprout extension.

162 activator) and its natural source, broccoli sprout extract (BSE) by gavage every other day for 3 mon

163 itive performance through a fast cholinergic sprouting followed by a slower glutamatergic reinnervati

164 han those from C57BL/6 mice and show greater sprouting following ischemic stroke.

165 Vessel networks expand when sprouts form new connections, a process whose regulation

166 docytic-defective mutant was able to prevent sprout formation in a fibrin bead assay, suggesting that

167 axonal bundle formation, collateral branches sprout from primary axons of the LOT.

168 f ERK and AKT/eNOS, and promoted microvessel sprouting from an angiogenesis animal model.

169 asculature is thought to form exclusively by sprouting from embryonic veins (lymphangiogenesis).

170 Ex vivo VEGF-induced vascular sprouting from Matrigel-embedded aortic rings isolated f

171 achieved by angiogenesis - endothelial cell sprouting from pre-existing vessels.

172 lymphatic vasculature forms independently of sprouting from veins.

173 ic reducing antioxidant power, especially in sprouts from citric acid-treated seeds.

174 artery, vein, capillaries and the primitive sprouting front.

175 o allow for their function as guideposts for sprout fusion and anastomosis.

176 e evaluated in chickpea (Cicer arietinum L.) sprouts germinated after soaking with different sodium s

177 Grains and sprouts had comparable Fe concentrations (78.2 +/- 2.65

178 Formononetin and the above sprouts has been shown to have a high affinity for ERbet

179 in vivo spared dermatome model of collateral sprouting identified the adaptor protein CD2-associated

180 l axons from the less affected hemisphere to sprout in the spinal cord.

181 ese mice as a tool to manipulate cholinergic sprouting in a disease-relevant way, we showed that this

182 Furthermore, despite induction of MF sprouting in a temporal lobe epilepsy model, KARs were n

183 sistent with an increase in lymphatic vessel sprouting in a three-dimensional lymphatic ring assay.

184 tubule formation in HMEC-1 cells, angiogenic sprouting in aortic ring explants, and retinal revascula

185 hile Dtx3l gain of function rescued impaired sprouting in Orai1 KO embryos.

186 ealing of skin wounds and reduced angiogenic sprouting in subcutaneous matrigel plugs.

187 CA1 pyramidal layer and robust morphological sprouting in the dentate gyrus.

188 making it unlikely that blocking sympathetic sprouting in the local DRGs or hindpaw was the sole mech

189 e we show that pericytes promote endothelial sprouting in the postnatal retinal vasculature.

190 nd had enhanced capacity to induce lymphatic sprouting in vivo This mutant may be useful for developi

191 etable soybean stage was superior to soybean sprouts in terms of content of protein (14% increase), Z

192 , riboflavin, and niacin) content of steamed sprouts increased with increasing germination time (p0.0

193 assay, we found CLEC14A to be a regulator of sprout initiation.

194 system drives significant spontaneous axonal sprouting instead of axon regeneration.

195 ons controlling hand muscles and extensively sprout into gray matter structures after SCI; therefore,

196 ar whether axons from other types of neurons sprout into the inner molecular layer and synapse with g

197 em in experimental epilepsy, involving fiber sprouting into the dentate molecular layer and a paralle

198 Here, we show that angiogenic sprouting into the injured area starts as early as 15 h

199 tain conditions (e.g., when the heading of a sprout is switched approximately between the long-axis d

200 The cholinergic sprouting is gender dependent and highly sensitive to th

201 ing the circuit-level determinants of axonal sprouting is important for repairing motor circuits afte

202 is a key regulator of angiogenesis, in which sprouting is regulated by an equilibrium between inhibit

203 born granule cells to functional mossy fiber sprouting is unknown, primarily due to technical barrier

204 nto the tip cells that lead new blood vessel sprouts is coordinated by vascular endothelial growth fa

205 wheat, the potential of eliminating severely sprouted kernels based on density differences in NaCl so

206 trol of dentate hyperactivity by cholinergic sprouting may be involved in functional compensation aft

207 Assembly of these vascular networks involves sprouting, migration and proliferation of endothelial ce

208 , miR-424 and miR-503 reduced LPS induced EC sprouting, migration and tube formation.

209 arily due to technical barriers in isolating sprouted mossy fiber synapses for analysis.

210 r profound frequency-dependent facilitation, sprouted mossy fiber synapses from adult-born cells exhi

211 We directly activated sprouted mossy fiber synapses from adult-born granule ce

212 Our results suggest that, although sprouted mossy fibers form recurrent excitatory circuits

213 Sprouting mungbean enhanced vitamin C content 2.7-fold c

214 Endothelial cells forming the sprout must develop front-rear polarity to allow sprout

215 The molecular systems that underlie axonal sprouting, neurogenesis, and gliogenesis after stroke ha

216 nnectivity and contribute to aberrant axonal sprouting observed in AD patients.

217 ant neurite outgrowth and hippocampal axonal sprouting observed in knock-in mice expressing FAD-linke

218 sFlt1: sflt1 mutants exhibit the venous over-sprouting observed in radial glia-ablated larvae, and sF

219 mic index by 38% was determined for elicited sprouts obtained after phenylalanine feeding.

220 starch digestibility was found for elicited sprouts obtained from seeds fed with tyrosine (a decreas

221 when either bulbs lost marketable quality or sprouting occurred.

222 Local axonal sprouting occurs, producing an increase in unmyelinated

223 nary vessels form in zebrafish by angiogenic sprouting of arterial cells derived from the endocardium

224 ds in the adult brain, we imaged post-lesion sprouting of cerebellar climbing fibres (CFs) in mice us

225 The concomitant sprouting of cholinergic terminals in the hippocampus ha

226 stered 28 d after stroke induced significant sprouting of corticospinal axons originating in the peri

227 eafferented hindlimb cortex, associated with sprouting of corticospinal axons.

228 ecruit activated stromal cells and guide the sprouting of endothelial cells in a spatially resolved m

229 pal dentate gyrus, seizures drive retrograde sprouting of granule cell mossy fiber axons.

230 of recombinant cleaved CLEC14A inhibited the sprouting of human and murine endothelial cells 3-fold i

231 aneous recovery was accompanied by extensive sprouting of intact rubrofugal and rubrospinal projectio

232 ells contribute to the pathologic retrograde sprouting of mossy fiber axons, both hallmarks of tempor

233 ion in assays of endothelial tube formation, sprouting of neovessels from murine aorta, and angiogene

234 Neurodegenerative lesions induce sprouting of new collaterals from surviving axons, but t

235 d human endothelial cells and stimulated the sprouting of rat aortic rings in culture.

236 c islet grafts was devoid of lesions because sprouting of recipient capillaries reestablished blood f

237 hances NG2 cell responses, axon sparing, and sprouting of serotonergic axons.

238 Sprouting of spared corticospinal tract axons in the con

239 in the pulp and to the healing mechanism by sprouting of the nerve fiber's terminal branches beneath

240 spinal cord promote axonal regeneration and sprouting of the optic nerve after crush and of supraspi

241 tion in zebrafish embryos leads to excessive sprouting of the trunk vessels around the spinal cord, a

242 eta signaling, promoted significant vascular sprouting of TNBC cells, in part, by direct repression o

243 As preharvest sprouting of wheat impairs its use in food applications,

244 Moreover, MSA effectively inhibited the sprouts of mouse aortic rings and neoangiogenesis in chi

245 n-filled dynamic subcellular structures that sprout on neuronal dendrites during neurogenesis.

246 yos bearing this deletion failed to initiate sprouting or differentiation of trunk lymphatic vessels

247 he results showed that turned green and also sprouting or rotting potato flesh contain high amounts o

248 q in axon growth and guidance to include the sprouting patterns of descending corticospinal tract axo

249 rter GCaMP3 unexpectedly inhibited lymphatic sprouting, presumably by disturbing calcium signaling.

250 To understand how collateral sprouting proceeds in the adult brain, we imaged post-le

251 pecification and intersegmental vessel (ISV) sprouting, processes regulated by Notch and Wnt.

252 6.7% and 17.1% in both untreated and treated sprouts, respectively.

253 of 40%, 31% and 23% in 3-, 4- and 5-day-old sprouts, respectively.

254 d while water samples did not test positive, sprout samples did test positive within 4 h of pre-enric

255 ntration and myrosinase activity in Brussels sprouts seedlings.

256 receded by transient contacts from extending sprouts, suggesting sampling of potential target sites,

257 We reveal that sprouted synapses from adult-born granule cells have a d

258 terminals, the functional characteristics of sprouted synapses would limit the contribution of adult-

259 The characteristics of these sprouted synapses, however, have been largely unexplored

260 UVECs to form significantly shorter and less sprouts than D551 fibroblast controls, suggesting that F

261 stimulation produced proprioceptive afferent sprouting that was accompanied by significant corticospi

262 83%, 56%, and 33%, respectively in chickpea sprouts that were treated with a high sodium selenite co

263 er of mossy cells, the extent of mossy fiber sprouting, the extent of astrogliosis, or the number of

264 oliferation that interferes with coordinated sprouting, thereby causing hyperplasia and vessel enlarg

265 on regulates barrier function and angiogenic sprouting through different mechanisms.

266 ocess, linking pulp fibroblasts to the nerve sprouting through the complement system activation.

267 (ECs) dynamically rearrange positions in the sprout to compete for the tip position.

268 specifically regulating the transition from sprouting to stabilization of nascent vessels.

269 e, we demonstrated that corticospinal fibers sprouting to the denervated side of the cord following p

270 increase the phytochemical profile of these sprouts to enhance their consumption in the diet.

271 Compared to untreated sprouts, total isoflavonoid, PAL activity and antioxidan

272 henolic content was determined for 2-day-old sprouts treated with 15 mM H2O2 (0.71 mg/gf.m.).

273 The sprouts treated with 20mM ascorbic acid had 22% and 23%

274 The sprouts treated with 2mM and 20mM ascorbic acid had a lo

275 Sprouts treated with CH, SA and H2O2 (7muM; 1 and 2mM, a

276 e of several nutraceutical compounds in bean sprouts treated with SA such as coumaric (8.5-fold), sal

277 uates in individual endothelial cells within sprouting vessels in the mouse retina in vivo and in cor

278 TGFBIp-induced lymphatic vessel sprouting was inhibited by addition of anti-integrin bet

279 a disease-relevant way, we showed that this sprouting was necessary and sufficient for the acute com

280 The yield of soybean sprouts was 632.4%.

281 ally bioaccessible fraction of stored lentil sprouts was elevated of 40%, 31% and 23% in 3-, 4- and 5

282 he reducing potential was determined for the sprouts washed with 20mM ascorbic acid.

283 Red clover sprouts were cultivated under different conditions (whit

284 Sprouts were grown under light/darkness cycles and compl

285 Seedlings of Brussels sprouts were used as a model, which constitutes a well-d

286 lower density kernels of mildly and severely sprouted wheat batches (11% and 16%, respectively), dens

287 flour in the bread formula was replaced with sprouted wheat flour (SF) characterized by enhanced nutr

288 Bread enriched with sprouted wheat flour had more resistant starch, but less

289 variability in enzyme activity in a batch of sprouted wheat, the potential of eliminating severely sp

290 hnique to increase the quality of a batch of sprouted wheat.

291 by inhibiting proliferation, migration, and sprouting, whereas siRNA-mediated knockdown increased sp

292 establish that pericytes promote endothelial sprouting, which results in the loss of side branches an

293 Phytate was less abundant in sprouts, which did not correlate with greater Fe bioacce

294 loss of function led to defective lymphatic sprouting, while Dtx3l gain of function rescued impaired

295 ble treatment to produce broccoli and radish sprouts with enhanced levels of health-promoting glucosi

296 loped significantly fewer and thinner aortic sprouts with fewer branch points than controls because o

297 y formed monolayers and underwent angiogenic sprouting within 7 days in culture.

298 significantly reduced the glutamatergic rMF sprouting within the dentate gyrus.

299 ary study integrates EC metabolism in vessel sprouting, yielding mechanistic insight in the control o

300 ous spinach, leek, lettuce, radish, Brussels sprouts, zucchini and chard samples were determined.