ライフサイエンスコーパス: stabilization

1 itical mechanism supporting long-term memory stabilization.

2 de novo transcription and PKC-dependent mRNA stabilization.

3 cytic sites, facilitates site initiation and stabilization.

4 enesis, inflammatory responses, and vascular stabilization.

5 antly affect nutrient cycling and carbon (de)stabilization.

6 points towards common mechanisms of plasmid stabilization.

7 mately 10-fold increase in IRF3 from protein stabilization.

8 ere genetically separable from effects on MT stabilization.

9 yrases to promote their deubiquitination and stabilization.

10 hich induced marked HIF-1alpha intracellular stabilization.

11 KT-mTORC1 signaling as a consequence of BRD4 stabilization.

12 h-tension mode, paralleling effects of actin stabilization.

13 used, with periodic breath holding for image stabilization.

14 rily depends on the electrochemical detector stabilization.

15 c core of ISD11, explaining the basis of ACP stabilization.

16 ay (HBP), increased O-GlcNAcylation, and p53 stabilization.

17 ate destabilization rather than ground-state stabilization.

18 e of allylic rather than oxocarbenium cation stabilization.

19 oning to the beta-phase leading to temporary stabilization.

20 al for the hyponitrite complex formation and stabilization.

21 ng core through osmolality-dependent helical stabilization.

22 ptide dosing in cells manifests KDM4A target stabilization.

23 tubulin has little impact on the observed MT stabilization.

24 nose-up sensations without compromising gaze stabilization.

25 m3 binding to tDNAs is increased upon R-loop stabilization.

26 ffected by vemurafenib treatment through RNA stabilization.

27 articipates in both upward and downward gaze stabilization.

28 ing energy that appears to drive nanocluster stabilization.

29 include signalling, compartmentalization and stabilization.

30 d inclusion ubiquitination and reduced Mcl-1 stabilization.

31 e the beneficial effects of statin on plaque stabilization.

32 in endothelial differentiation and vascular stabilization.

33 e favorable environment for transition-state stabilization.

34 l maturation and decreases at the time of OR stabilization; (2) colocalizes with the repressor CoREST

35 e scratch wound assay of cell spreading, HIF stabilization accelerated, whereas HIF1alpha shRNA delay

36 essiveness through sequential beta1 integrin stabilization, activation of an ILK/EGFR/Ras/NF-kappaB s

37 1 and show that THOR contributes to the mRNA stabilization activities of IGF2BP1.

38 llenge posed by the competition of nonnative stabilization against native-centric forces is conceptua

39 Second, upon stabilization, all of these binary superlattices could b

40 the BM niche, resulting in Wnt (co)receptor stabilization and a dramatically increased sensitivity t

41 Here we show a mechanism for NALP7 protein stabilization and activation of the inflammasome by Toll

42 sm in distal dendrites required for dendrite stabilization and arbor outgrowth.

43 ual and vestibular reflexes supporting image-stabilization and balance.

44 development, but only when locomotor-driven stabilization and control of movement initiation are bot

45 tors in atrial monolayers could lead to both stabilization and destabilization of reentrant activity.

46 g scientific understanding of processes of C stabilization and destabilization over various timescale

47 n DNA end resection by coordinating both the stabilization and exclusion of Rad9 from DNA lesions.

48 nd that this system is critical for thrombus stabilization and growth have identified factor XII (FXI

49 r, this study uncovering Skp2-mediated Twist stabilization and oncogenic functions in CRPC offers new

50 gh genetic and chemical methods reverses p53 stabilization and rescues the Mpi-deficient phenotype.

51 , Dia1 and Dia2 facilitated HIV-1-induced MT stabilization and the intracellular motility of virus pa

52 et of HdeA, is important in controlling HdeA stabilization and thus the acid activation of this chape

53 ependent signaling cascade, resulting in the stabilization and transcriptional activation of phosphor

54 sphorylation of Sox2 at T118, leading to its stabilization and transcriptional activation.

55 ion of HIF-1alpha acetylation, enhancing the stabilization and transcriptional activity of HIF-1alpha

56 taining to their extraction, solubilization, stabilization, and crystallization, as well as reconstit

57 t residues K280/K281 impairs tau-mediated MT stabilization, and enhances the formation of fibrillar t

58 t thermophilic anaerobic digestion, alkaline stabilization, and pasteurization led to the most extens

59 e MK2, thereby promoting transcription, mRNA stabilization, and translation of target genes.

60 Thus, D292V-induced blocked-state stabilization appears to disrupt the delicately poised e

61 nduced and relaxation-induced voltage-sensor stabilization are separable.

62 r, the molecular-level mechanisms of kinetic stabilization are unclear, and the fundamental thermodyn

63 es, of which early detection and therapeutic stabilization are urgently needed.

64 allographic structures, ligand-dependent LBD stabilization assays, and cell-based transactivation mea

65 e on tankyrase 1 in late S/G2 to promote its stabilization, association with telomeres, and resolutio

66 ility due to physical isolation and chemical stabilization at the organic-mineral interface.

67 f let-7a and let-7b, thus promoting MYC mRNA stabilization at the post-transcriptional level.

68 s with septic shock, 2) a "resuscitation and stabilization bundle" to help adherence to best practice

69 lation is a method of choice for sialic acid stabilization, but the harsh conditions during permethyl

70 ements when dispersion forces, which mediate stabilization by confinement in host-guest systems, are

71 catalytic mechanism involving leaving group stabilization by H155 in motif 2 and water coordination

72 The pseudoknot stabilization by magnesium, in combination with P1 stabi

73 ization by magnesium, in combination with P1 stabilization by SAM, explains the requirement of both S

74 G4 stabilization by small-molecule compounds called G4 liga

75 e kinetic and thermodynamic basis of kinetic stabilization by the MTAs paclitaxel, an assembly promot

76 longer than aqueous W(*) due to significant stabilization by the protein.

77 represents the sum of 11.8 and 10.6 kcal/mol stabilization by the substrate phosphodianion and the ri

78 energies can then be understood in terms of stabilization caused by spin-coupling augmented by dispe

79 inblastine, and the other a "pseudo" kinetic stabilization, characteristic of paclitaxel, that nearly

80 ration, suggesting acetylation-induced HIPK2 stabilization contributed to the enhanced activation of

81 r using an individualized visual acuity (VA) stabilization criteria in patients with visual impairmen

82 ugh reduced hypoxia-inducible factor 1 alpha stabilization) decrease the expression of the most abund

83 n NT-proBNP reduction of >30% after clinical stabilization did not improve 6-month outcomes.

84 l complex, and that loss of AnkG after nodal stabilization does not lead to rapid nodal disassembly b

85 MoS2 to metallic 1T phase, high porosity and stabilization effect of nickel-cobalt complexes on 1T ph

86 kcal/mol is comparable with calculations of stabilization effects in other systems, demonstrating ho

87 Computed singlet-triplet gaps and biradical stabilization energies indicated weak interaction betwee

88 with the reaction energies and the resonance stabilization energies provided by the various substitue

89 M/GBSA calculations converge in indicating a stabilization energy at pH 5.0, 2-fold higher than that

90 erred configurations are driven by the large stabilization energy of overlapping SOMOs.

91 ation irreversible due to favorable aromatic stabilization energy, while extended linear benzannelati

92 Y14Cav1 regulation of focal adhesion protein stabilization, focal adhesion tension, and cancer cell m

93 ical CRE trend among adult inpatients showed stabilization following a rapid rise since introduction

94 t cycloarenes gain little, if any, energetic stabilization from global delocalization, obviating the

95 osyl ring, respectively, and an 8.6 kcal/mol stabilization from the orotate ring.

96 regulating their maturation, activation, and stabilization have a remarkably distinct biological impa

97 Despite successfully achieving substantial stabilization, however, almost all mutations decreased p

98 ORs) are the dominating contributors to gaze stabilization in all vertebrates.

99 sceptible to light and heat and thus require stabilization in aqueous medium.

100 on of the UPR is linked to decreased ATG16L1 stabilization in Ikkalpha(AA/AA) mice.

101 We identify two distinct modes of kinetic stabilization in live cells, one that truly suppresses o

102 markers thus providing evidences for plaque stabilization in mice with advanced atherosclerosis.

103 ic materials and soil minerals may promote C stabilization in Oxisols.

104 ptic properties and its involvement in color stabilization in red wine are well established.

105 ng and remarkably frequent mechanism of fork stabilization in response to genotoxic insults.

106 In contrast, colloidal stabilization in solvents with low polarity, such as hex

107 MMP-9 decreased in parallel to clinical stabilization in the 12 patients involved in the open la

108 o-lysosomal compartments and that additional stabilization in the 5'-regions of both siRNA strands si

109 inst that in bis(diamantane), and dispersion stabilization in the latter is quantified.

110 Dub3 and inhibits the Dub3-mediating Snail1 stabilization in vitro and in vivo.

111 al-specific genes with key roles in vascular stabilization including claudin-5, vascular endothelial-

112 PATs of heterologous mRNAs with concomitant stabilization, including ribosomal protein (RP) mRNAs.

113 nal-regulated kinase activation, while spine stabilization involved transcription-independent protein

114 act for simultaneous object pursuit and gaze stabilization is not understood.

115 For Li(+) and Na(+), the stabilization is such that hydrogenated dimers are obser

116 biquitin ligase for ERG and propose that ERG stabilization is the oncogenic effector of SPOP mutation

117 tency, the mechanism of intercellular bridge stabilization is unclear.

118 ng of the driving forces for their colloidal stabilization is very limited.

119 of RNA molecules are essential in, e.g., RNA stabilization, localization, and protein interaction, an

120 digestion (AD), thermal drying (TD), or lime stabilization (LS) treatment processes.

121 Assuming that colonization opportunities and stabilization mechanisms would allow peat to persist in

122 he emergence of nanoshells and some of their stabilization mechanisms.

123 This stabilization mode is equivalent to a sigma(2), pi-coord

124 Following stabilization, myelin sheaths grow along axons, and we f

125 i-As content which is also suitable for its stabilization namely, cooking bran in percolating arseni

126 The data suggest that this stabilization occurs as a result of reconfiguration of t

127 subsequent new learning until after passive stabilization occurs hours later.

128 the intermediary redox state and additional stabilization of 2 from structural reorganization, leadi

129 n fully dense, nanostructured metals via the stabilization of a mechanically unstable, negative stiff

130 7 pyrochlore iridate, that it results in the stabilization of a monopole crystal, which exhibits magn

131 eus to the cytoplasm, specifically promoting stabilization of a new target, poly (ADP-ribose) glycohy

132 omputational studies indicate that increased stabilization of a partial positive charge on the nitro-

133 gment, PdMe2, allows the rapid formation and stabilization of a Pd(IV) tris-alkyl moiety after oxidat

134 ting properties were observed, revealing the stabilization of a weak-coupling type-II-like supercondu

135 Furthermore, the stabilization of actin network with jasplakinolide had n

136 ehavior in hERG channels, which results from stabilization of activated channel states.

137 her showed that fine-sized residues promoted stabilization of aliphatic C-H and carboxylic C=O compou

138 ependent on their positioning, the resulting stabilization of anionic transition states on fullerenes

139 n signalling, and modulate the autocatalytic stabilization of auxin signalling output.

140 the degradation of tankyrases and consequent stabilization of Axin to antagonize Wnt signaling.

141 in developmental synapse maturation and the stabilization of axonal inputs and reveal a potential ro

142 motes the proteolysis of Axin and consequent stabilization of beta-catenin.

143 ymerization experiments demonstrated a hyper-stabilization of both mitotic and interphase MTs.

144 With the stabilization of breast cancer incidence and substantial

145 We propose SPOP(MT)-induced stabilization of c-MYC protein as a novel mechanism that

146 sly undetected by AFM and then measuring the stabilization of calmodulin by myosin light chain kinase

147 Electrostatic stabilization of charged solutes works well in solvents

148 applications in memory or logic devices, the stabilization of chiral spin textures in in-plane magnet

149 In correlation with EYA1-mediated stabilization of cMyc and reduced levels of pT58, EYA1 g

150 at is optimal for Abeta phagocytosis and the stabilization of cognitive decline.

151 presentation of multiple events and promotes stabilization of complex memory networks.

152 fluctuations on mitosis or on ATP-depletion/stabilization of cortex correlate with increased tension

153 nterference, whereas sleep engaged a lasting stabilization of cortical traces and consequent trace do

154 e role of KO(t)Bu is traced, in part, to the stabilization of crucial intermediates through cation-pi

155 Furthermore, ADAR2-mediated stabilization of Ctn RNA occurred in an editing-independ

156 Complexation with beta-CD showed a thermal stabilization of cy3glc, resulting on a decrease of the

157 ify amino acid mutations that would increase stabilization of Dbh bound to DNA.

158 tion of the FBXW7-DISC1 complex results in a stabilization of DISC1.

159 receptor regions that are important for the stabilization of distinct conformations underlying funct

160 ms for functional specialization: structural stabilization of each loop conformation and substrate-sp

161 tates of the Pol I cleft, in addition to the stabilization of either Rrn7 N-terminal domain near Pol

162 kthroughs have stimulated further design and stabilization of Env trimers as well as other platforms

163 kely coupled with enhanced sequestration and stabilization of ER- associated miRNPs observed in infec

164 n occurs downstream of the hypoxia-dependent stabilization of ERF-VII proteins and independently of t

165 study, we evaluated the effects of improved stabilization of F in the pre-F conformation and of codo

166 e solid support by reductive amination; (ii) stabilization of fragile sialic acids by carbodiimide co

167 eding replication by small-molecule-mediated stabilization of G-quadruplex nucleic acid secondary str

168 Chemical stabilization of G4 DNA in PARP3(-/-) cells leads to wid

169 s carbonyl and amide groups in hydrogen-bond stabilization of helical structures is a major factor, w

170 participants who received a high dose, with stabilization of hemostasis and a profound reduction in

171 the important hepcidin residues involved in stabilization of hepcidin-GDP complex.

172 Chemical stabilization of HIF-1alpha by Dimethyloxalylglycine (DM

173 ansformed cell lines suggested that normoxic stabilization of HIF-1alpha explains the persistent expr

174 Moreover, pharmacologic stabilization of HIF-1alpha in the liver stimulated HMGC

175 Hypoxic incubation (3 kPa) caused (i) stabilization of HIF-2alpha and up-regulation of hypoxia

176 Cancer cells undergoing pharmacological stabilization of HIFs retained their constitutive abilit

177 hase engineering using a strategy of entropy stabilization of high-symmetry alloys.

178 GNs counteract linker histone (H1)-dependent stabilization of higher order 'tertiary' chromatin struc

179 IMP2 stabilization of HMGA1 mRNA plus IMP2 stimulated IGF2 pr

180 ng activity exerting a function in selective stabilization of host proteins and protection from host

181 We also demonstrate that MUC1-regulated stabilization of hypoxia inducible factor-1alpha (HIF-1a

182 Hypoxia and stabilization of hypoxia-inducible factors (HIFs) are ha

183 Moreover, our results demonstrate that stabilization of iChS by chemical modifications favors a

184 Genetic stabilization of IFNAR1 improved CTL survival and increa

185 Likewise, pharmacologic stabilization of IFNAR1 suppressed tumor growth providin

186 osin levels is a conserved mechanism for the stabilization of intercellular bridges that can occur by

187 Stabilization of ITGA4-mRNA with SSB proteins resulted i

188 ein involved in translational regulation and stabilization of its mRNA targets in heart muscle.

189 e that Ndc80-tail dephosphorylation promotes stabilization of kinetochore-microtubule attachments via

190 -binding protein (TRBP) promotes binding and stabilization of Lin28a, but not Lin28b, with an accompa

191 production of hydrogen sulfide which favors stabilization of metals in aquifer solids.

192 borated by impaired compartmentalization and stabilization of miRNP components in Mfn2-depleted mamma

193 Stabilization of MLL provides us with a paradigm in the

194 The editing-dependent stabilization of mRNAs in turn alters the observed editi

195 AP2 to drive both nucleation and subsequent stabilization of nascent CCPs.

196 lcium-dependent feedback for the homeostatic stabilization of neurotransmission.

197 Energetic stabilization of one of the CDN constituents leads to a

198 ture expression of Cdkn2a and the consequent stabilization of p53, an effector of the pre-Ag receptor

199 chromosomes together and is required for the stabilization of pairing interactions and the completion

200 pot formulation for treatment initiation and stabilization of patients with OUD, with the further ben

201 eviously introduced coarse-grained model for stabilization of proteins by sugars.

202 n of nfGNPs salt-induced aggregation and the stabilization of purified VLPs.

203 nd 40microg/g of lycopene, for the oxidative stabilization of ROO and RSO, respectively.

204 Stabilization of specific domain-domain interactions via

205 Through stabilization of such bundles, plastins contribute, in a

206 underpin three crucial factors dictating the stabilization of super-swelled lipid bicontinuous cubic

207 The stabilization of surfactant-assisted synthesized colloid

208 signalling is an essential platform for the stabilization of synaptic transmission throughout the de

209 Likewise, stabilization of tetrameric PKM2 by a chemical approach

210 strate that phosphorylation-dependent excess stabilization of the actin cytoskeleton is a key phospho

211 We interpret this to indicate that stabilization of the activated voltage sensor limits the

212 o functions have been assigned to properdin; stabilization of the alternative convertase, C3bBb, is w

213 t on the synthesis of [2]rotaxanes driven by stabilization of the axle-forming transition state.

214 ia and flagella, where it is involved in the stabilization of the axoneme.

215 Stabilization of the bent conformation by integrin trans

216 MBOA-Glc is produced by D. virgifera through stabilization of the benzoxazinoid breakdown product MBO

217 This allows the stabilization of the bijel far from the demixing point o

218 Importantly, pharmacological stabilization of the binding of calstabin2 to RyR2 chann

219 omplement alternative pathway (AP) providing stabilization of the C3 and C5 convertases, but its olig

220 t induce the incorporation of O as necessary stabilization of the crystal structure.

221 rcellular bridges are proposed to arise from stabilization of the cytokinetic ring during incomplete

222 ivity of tumor necrosis factor alpha through stabilization of the distorted trimer with small molecul

223 The crystal field stabilization of the dxy orbital due to c-axis contracti

224 The ASC-mediated stabilization of the ECs clearly reduced vascular permea

225 the amyloidogenic peptide contributes to the stabilization of the experimentally observed antiparalle

226 y, dissociation constant measurements show a stabilization of the HdeA dimer upon exposure to mildly

227 Here we describe the stabilization of the heaviest 4+ ion of the periodic tab

228 a role in target-cell surface recognition or stabilization of the heptameric pore complex.

229 opologues can be prepared, indicating strong stabilization of the higher-energy cis conformer by a ni

230 With heteroatom stabilization of the intermediate allylic free radical t

231 3O4, Mn2O3, and MnO2), consistent with added stabilization of the layer and tunnel structures at the

232 es on phenothiazines 3-7 exhibit substantial stabilization of the LUMO with the increase in acceptor

233 ensable role in the maturation and long-term stabilization of the newly assembled nodal complex, and

234 the bacterial tubulin homolog FtsZ, and the stabilization of the newly formed Z-rings is crucial for

235 ), a protein required for the activation and stabilization of the NLRP3 inflammasome.

236 gh a "non-CO" pathway for MOR because of the stabilization of the OH* intermediate by Zn atoms, while

237 equently, it was proposed that an open-state stabilization of the PD imposes a mechanical load on the

238 reover failed to promote the HSP90-dependent stabilization of the PDE6alpha subunit in the cytosol.

239 the role of the trifluoromethyl group in the stabilization of the peptide bond geometry.

240 However, despite the resonance stabilization of the pi system of triplet O2, the weakne

241 selection thymocyte survival in part through stabilization of the pro-survival protein Bcl-2.

242 functional theory study of the halogen bond-stabilization of the pyrazine (Pz) anion, an unstable an

243 However the stabilization of the raw material after pruning remains

244 hain functional groups, and transition-state stabilization of the S(VI) exchange reaction all seem to

245 ry under hyperosmotic stress, partly through stabilization of the sigma factor RpoS.

246 ers were then employed as excipients for the stabilization of the therapeutic protein granulocyte col

247 ubstitution of semibullvalene results in the stabilization of the transition state and a further lowe

248 inetic parameters shows that the 31 kcal/mol stabilization of the transition state for decarboxylatio

249 e contributes the most to the electric field stabilization of the transition state of the LDE variant

250 ite to be remodeled to enable more efficient stabilization of the transition state of the reaction.

251 G4 calculations both find that the resonance stabilization of the two unpaired electrons in triplet O

252 replication was elevated, probably due to a stabilization of the viral replication factor E2.

253 relative contribution of either mechanism of stabilization of the voltage sensor.

254 rs increased dramatically corresponding with stabilization of their circadian periods.

255 cible Factors, whose activity depends on the stabilization of their labile alpha subunit.

256 ar solvents such as toluene enable increased stabilization of these iron species and further enabled

257 Overnight stabilization of this detector is advised, and, after th

258 AF65, which promotes mRNA processing and the stabilization of transcripts involved in homologous reco

259 telomeres from damage through Nek7-dependent stabilization of TRF1.

260 e, we provide the first structural basis for stabilization of triple helical collagen peptides contai

261 The lack of stabilization of TS by these solutes indicates that O ph

262 These observations demonstrate that the stabilization of widespread gain signals affecting alrea

263 Stabilization or reversibility of PoPH seems to be an at

264 to the 3' terminus, thus leading to pre-mRNA stabilization, or decay depending on the occurrence and

265 uring nose-up postures while preserving gaze stabilization performance.

266 This premature stabilization requires the conserved microtubule-binding

267 Finally, pharmacological cardiolipin stabilization reverted the energetic impairment, confirm

268 ts may reflect a protein scaffold or complex stabilization role of NUWA between E(+)-type PPR and DYW

269 man Timeless is involved in replication fork stabilization, S-phase checkpoint activation and establi

270 ing RNA (piRNA)-independent manner, and MIWI stabilization sequesters RNF8 in the cytoplasm of late s

271 s with varying dihedral angles that the hole stabilization shows two different regimes where the mech

272 methods (no additive, 95% ethanol, RNAlater Stabilization Solution, fecal occult blood test cards, a

273 ting the open-label period, subjects meeting stabilization/stable-responder criteria were randomized

274 e-dependent arch motions to transition-state stabilization suppresses inappropriate or premature clea

275 tional palmitoylation of mVEGFR1 is a binary stabilization switch, and ligand engagement leads to dep

276 rent regimes where the mechanism of the hole stabilization switches over from (static) delocalization

277 The Pound-Drever-Hall laser stabilization technique is widely used to stabilize diff

278 d in an early, Rho family-independent, actin stabilization that is integral to the formation of one R

279 The time to hemodynamic stabilization, the risk of catecholamine therapy and the

280 -tert-butylphenyl, R = NC(t)Bu2) for kinetic stabilization, the synthesis of a rare terminal Fe(IV) n

281 e "preferential exclusion" theory of protein stabilization), this study indicates that each co-solute

282 his analysis indicates that hyperconjugative stabilization through sigmaCC -->sigma*CF interactions a

283 ing vascular quiescence and long-term vessel stabilization through their interactions with endothelia

284 olling actin nucleation and microtubule (MT) stabilization to facilitate processes such as cell polar

285 sequence of events leading to voltage sensor stabilization upon membrane depolarization.

286 dicating distinct requirements of functional stabilization versus antibody recognition.

287 erization domain stimulation promote ATG16L1 stabilization via IKKalpha-dependent phosphorylation of

288 Stabilization was independent of tyrosine kinase signali

289 Interestingly, stabilization was manifested through the same acceptor m

290 The best stabilization was observed using the trehalose- and zwit

291 tential impact of these Tau activities on MT stabilization, we incorporated them into our previously

292 gmentation for anthocyanin encapsulation and stabilization were fabricated.

293 well as soil textural effects on soil carbon stabilization were larger than direct temperature uncert

294 ide and occur at the time of transcriptional stabilization, whereas ICM cells still retain the abilit

295 oduces and validates an approach for protein stabilization which should be applicable to a variety of

296 is enhanced upon Taxol-mediated microtubule stabilization, which, together with the signaling data,

297 tide and provide a structural basis for this stabilization with an atomic resolution crystal structur

298 the synergism between HIF overexpression and stabilization within the hypoxic BM microenvironment pro

299 , impeded the faster phase of voltage sensor stabilization without attenuating the slower phase, sugg

300 f ECM genes during WL and a period of weight stabilization (WS) and the risk of weight regain.In this